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Parma Summer School 2018 15-17 May 18, Parma Emerging Risks Ana Afonso Scientific Committee and Emerging Risks Unit

Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Page 1: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

Parma Summer School 201815-17 May 18, Parma

Emerging Risks

Ana AfonsoScientific Committee and Emerging Risks Unit

Page 2: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Expectations

Communication

Effectiveness

EFSA, mission and tasks

Objectives

Emerging risks definition

Drivers

Examples

ERI procedure

What works

What is important

Page 3: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Experience has shownthat it is necessary toadopt measures aimed atguaranteeing that unsafefood is not placed on themarket

FOOD LAW

Page 4: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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EFSA 2020 STRATEGY

Prioritise public engagement in the process ofscientific assessment

Widen EFSA’s evidence base and maximise accessto its data

Build the EU’s scientific assessment capacity andknowledge community

Prepare for future risk assessment challenges

Create an environment and culture that reflectsEFSA’s values

Page 5: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Anticipation of future risk assessment needs

Data / Knowledge

Risk assessment methods

Help risk manager anticipate and even preventfuture safety challenges

EMERGING RISKS – WHY ARE WE INTERESTED?

Page 6: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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A function of theprobability of an adversehealth effect and theseverity of that effect,consequential to a hazard;

RISK

Page 7: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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an emerging risk to human, animaland/or plant health is understood as arisk resulting from a newly identifiedhazard to which significant exposuremay occur or from an unexpectednew or increased significantexposure and/or susceptibility to aknown hazard” (EFSA 2007).

EMERGING RISK

Page 8: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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NEW CHALLENGES AND THREATS

Environmental risks e.gmultiple stressors and bees

Evaluation of the safety ofnew products

•e.g. novel foods

Development of newassessment methods:

•nanotechnology, active andintelligent packaging

•‘-omics’, less animal testing

Chemical mixtures/ combinedtoxicity of substances in food

Antimicrobial resistance

Hazards linked toglobalisation: plant pests,animal diseases, vector-borne diseases

Page 9: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Drivers

Pathways

Sources

Outcome

WHY DO THINGS CHANGE?

Page 10: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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DRIVERS OF INFECTIOUS DISEASE THREAT EVENTS

Foodborne and waterborne IDTEs (Semenza et al 2016)

Page 11: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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EMERGING RISK DRIVERS

How do we recognise changes?

How can we anticipate changes? Is predictionpossible?

What are the implications of changes formanaging risk?

Can we learn from the past?

Page 12: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Micro-organisms, pests, parasitesand prions having a direct or indirectimpact on the safety of the food and feedsupply chains, animal health and welfare,and plant health

EMERGING BIOLOGICAL RISKS

Page 13: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Q FEVER

Page 14: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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CULTURAL AND METHODOLOGICAL CHALLENGES

Emerging disease risk is a local issue with aglobal dimension.

The emergence of a pathogen involves acombination of changes in key drivers.

Most drivers for emerging issues are common tohuman, veterinary, plant and ecosystem health

Pathogen discovery - Pathway discovery

Page 15: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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ERI PROCEDURE

Identificationof priorityemerging

issues

Informationsources and

data collection

Evaluation toidentify

emerging risks

Page 16: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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ACCESSIBLE DATA

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TEXT MINING: “EMERGING RISK FOOD”

false negatives

noise avoided noise

Flagged Overlooked

spot on

Page 18: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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PRIORITIZATION

Novelty

Soundness

Severity

Imminence

Scale

UNCERTAINTY

AMBIGUITY

RISKPERCEPTION

Page 19: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Where is the life we have lost in living?

Where is the wisdom we have lost inknowledge?

Where is the knowledge we have lostin information?

T. S. Eliot

Page 20: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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EFSA SCIENTIFIC PANELS

Plant protection

GMO

Plant health

Animal health & welfare

Nutrition

Food Packaging

Animal feed

Biological hazards

Chemical contaminants

Food additives

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WITHIN EUROPE...

National food safety agencies

from 28 EU Member States

400 research institutes

EU Agencies

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OUTSIDE EUROPE...

Partners

Establishedcooperation

IPA/ENP countries

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NETWORKS OF KNOWLEDGE

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Identification of relevant issues

Expertise and networking are a vital part ofthe process, particularly for filtering signals

Sharing information without creatingunnecessary scares

Focused monitoring and follow-up activities

WHAT HAS WORKED

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IDENTIFICATION OF EMERGING ISSUES

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Evaluation of the collected information andidentification of emerging risks

Avoided risks are often “invisible”

EVALUATION

Page 28: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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Aim (and defining success)

How to handle uncertainty

It is not only risk assessment

IMPORTANT

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Page 30: Emerging Risks - Europa · EFSA 2020 STRATEGY Prioritise public ... intelligent packaging •‘-omics’, less animal testing Chemical mixtures/ combined toxicity of substances in

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SCER- ER Team

Caroline Merten, RaquelGarcia Mata, AngeloMaggiore, Agnes Rortais,Tilemachos Goumperi,Tobin Robinson

EFSA Staff

EFSA experts

Emerging Risks Exchange Network

Stakeholders discussion group

JRC

DG SANTE

ECDC

FAO……..

ACKNOWLEDGEMENTS

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THANK YOU