EFFECTS OF POTASSIUM DIFORMATE ON PIGLETS

Dr XIA DONGInstitute of animal husbandry & veterinary science, Shanghai Academy of Agricultural Sciences (SAAS)xiadong@saas.sh.cn

Agricultural Biological Ggene Center

Horticulture Institute

Institute for Agri-food standards and testing technology

Scientific andTechnological Information Institute in agriculture

Eco-Environmental Protection Institute

Crop and Forest & Fruit Tree Institute

Edible Fungi Institute

Institute of animal husbandry and veterinary ScienceThe Biotechnology Institute

Shanghai Academy of Agricultural Sciences (SAAS)

Zhuanghang Agricultural Science and Technology Experimental Station

Animal husbandryPoultryPig scienceSmall ruminantAnimal environment & welfare

Institute of animal husbandry and veterinary Science

Shanghai white PigLitter size 13.

Pudong white PigLitter size: 15.

Meishan pigLitter size: 16

Local breeds in Shanghai

Hu sheep mature early, tender meat.

Chongming Goats

Agricultural endocrine disruptors on the reproductive function

Reproductive performance

Hormones variation

Mating behavior

Secondary organ development

Animal Environment & Welfare

Dong Xia, Nahid Parvizi, Yuchuan Zhou, Kesi Xu, Hui Jiang, Rongjie Li, Yiqiong Hang, Yang Lu. Paternal fenvalerate exposure influences reproductive functions in the offspring. Reproductive Science . 2013, 20 (11): 1308-1315

Nutrition, environment & Welfare• Sow: Diet fiber, gut microflora, fertility & healthy• Weaning piglet: non antibiotic feeding

N=6, 15 male piglets in each replication

EFFECTS OF POSTASSIUM DIFORMATE (KDF) ON WEANING PIGLETS

HCOOH·HCOOK

KDF: Control diet + 1% KDF

Item Control

KDF

Plasm IGF-1 (ng/mL)

11.69±1.90

8.92±0.54

Hepatic IGF-1 (ng/mg protein)

0.37±0.01

1.06*±0.03

Mean ±SEM, N=6, P≤0.05Internal control: 18S rRNA

Abbreviations: G6PC=glucose-6-phosphatasePCK=phosphoenolpyruate carboxykinaseFBP=fructose-1,6-bisphosphatase

Mean ±SEM, N=6, P≤0.05Internal control: 18S rRNA

Yali Zhou, Xihui Wei, Zhenggao Zi, Bingjie Zou, Shuangshuang Xia, Naisheng Lu, Hulong Lei, Yang Lu, Nahid Parvizi, Dong Xia. Potassium diformate influences gene expression of GH/IGF-I axis and glucose homeostasis in weaning piglets. Livestock Science. 2015, 172 (1): 85-90

ConclusionAddition of 1% KDF to the diet have positive effect on the growteh performance in the weaning piglets, and this improvement may associate with the regulation of GH axis and hepatic glucose homeostasis

Question?

Dietary KDF ?

KDF: Control diet + 1% KDFN=6, 15 male piglets in each replication

At the 2nd week

The Effects of Potassium Diformate on the Early Stage of Weaning Piglets

Additon of 1% KDF can decrese the level of LPS in the serum.

Additon of 1% KDF to diet do not change the digesta pH of GI, it decrease the diversity of the microflora and the ratio of Enterobacteria copies in the digesta, but this influence effect are differ in different part of GI. ?

Lipopolysaccharides ， LPS

04/21/23

KDF ? ?