外部評価報告書 2019

神戸大学大学院科学技術イノベーション研究科

外部評価委員会概要・・・・・・・・・・・・・・・・・・・・・・・・・・・・ 1

外部評価委員会資料　科学技術イノベーション研究科外部評価書（教育）・・・・・・・・・・・・・ 5　科学技術イノベーション研究科外部評価書（研究）・・・・・・・・・・・・・ 37　科学技術イノベーション研究科研究業績説明書・・・・・・・・・・・・・・・ 77 　科学技術イノベーション研究科の概要説明・・・・・・・・・・・・・・・・・101

外部評価委員会委員 意見書 ・・・・・・・・・・・・・・・・・・・・・・・・159

あとがき・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・161

神戸大学大学院科学技術イノベーション研究科外部評価検討WG委員名簿・・・・163

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Christopher J. Vavricka, Takanobu Yoshida, Yuki Kuriya, Shunsuke Takahashi, Teppei Ogawa, Fumie Ono, Kazuko Agari, Hiromasa Kiyota, Jianyong Li, Jun Ishii, Kenji Tsuge, Hiromichi Minami, Michihiro Araki, Tomohisa Hasunuma, Akihiko Kondo. "Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids" Nature Communications, 10, 2015, May 2019. DOI: 10.1038/s41467-019-09610-2 Satomi Banno, Keiji Nishida, Takayuki Arazoe, Hitoshi Mitsunobu, Akihiko Kondo. "Deaminase-mediated multiplex genome editing in Escherichia coli" Nature Microbiology, 3(4), 423-429, Apr. 2018. DOI: 10.1038/s41564-017-0102-6 Megumi Miyano, Kosei Tanaka, Shu Ishikawa, Shinji Takenaka, Andrés Miguel-Arribas, Wilfried J. J. Meijer, Ken-ichi Yoshida. "Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer" Microbial Cell Factories, 17(1), 13, Jan. 2018. DOI: 10.1186/s12934-017-0855-x Daisuke Sasaki, Kengo Sasaki, Naoko Ikuta, Takahiro Yasuda, Itsuko Fukuda, Akihiko Kondo, Ro Osawa. "Low amounts of dietary fibre increase in vitro production of short-chain fatty acids without changing human colonic microbiota structure" Scientific Reports, 8(1), 435, Jan. 2018. DOI: 10.1038/s41598-017-18877-8

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Zenpei Shimatani, Sachiko Kashojiya, Mariko Takayama, Rie Terada, Takayuki Arazoe, Hisaki Ishii, Hiroshi Teramura, Tsuyoshi Yamamoto, Hiroki Komatsu, Kenji Miura, Hiroshi Ezura, Keiji Nishida, Tohru Ariizumi, Akihiko Kondo. "Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion" Nature Biotechnology, 35(5), 441-443, May 2017. DOI: 10.1038/nbt.3833 Shih-Hsin Ho, Akihito Nakanishi, Yuichi Kato, Hiroaki Yamasaki, Jo-Shu Chang, Naomi Misawa, Yuu Hirose, Jun Minagawa, Tomohisa Hasunuma, Akihiko Kondo. "Dynamic metabolic profiling together with transcription analysis reveals salinity-induced starch-to-lipid biosynthesis in alga Chlamydomonas sp. JSC4" Scientific Reports, 4, 45471, Apr. 2017. DOI: 10.1038/srep45471 Keiji Nishida, Takayuki Arazoe, Nozomu Yachie, Satomi Banno, Mika Kakimoto, Mayura Tabata, Masao Mochizuki, Aya Miyabe, Michihiro Araki, Kiyotaka Y. Hara, Zenpei Shimatani, Akihiko Kondo. "Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems" Science, aaf9729, Sep. 2016. DOI: 10.1126/science.aaf8729

Norihiro Togo, Keizo Nakagawa, Takuji Shintani, Tomohisa Yoshioka, Tomoki Takahashi, Eiji Kamio, Hideto Matsuyama. "Osmotically assisted reverse osmosis utilizing hollow fiber membrane module for concentration process" Industrial & Engineering Chemistry Research, 58(16), 6721-6729, Mar. 2019. DOI:10.1021/acs.iecr.9b00630 Hao-Chen Wu, Tomohisa Yoshioka, Keizo Nakagawa, Takuji Shintani, Toshinori Tsuru, Daisuke Saeki, Abdul Rajjak Shaikh, Hideto Matsuyama. "Preparation of Amphotericin B-Ergosterol structures and molecular simulation of water adsorption and diffusion" Journal of Membrane Science, 545, 229-239, Jan. 2018. DOI:10.1016/j.memsci.2017.09.032 Hao-Chen Wu, Tomohisa Yoshioka, Keizo Nakagawa, Takuji Shintani, Toshinori Tsuru, Daisuke. Saeki, Yi-Rui Chen, Kuo-Lun Tung, Hideto Matsuyama. "Water transport and ion rejection investigation for application of cyclic peptide nanotubes to forward osmosis process: A simulation study" Desalination, 424, 85-94, Dec. 2017. DOI:10.1016/j.desal.2017.09.008 Hao-Chen Wu, Tomohisa Yoshioka, Hiroki. Nagasawa, Masakoto Kanezashi, Toshinori Tsuru, Daisuke Saeki, Hideto Matsuyama. "Preparation of cyclic peptide nanotube structures and molecular simulation of water adsorption and diffusion" Journal of Membrane Science, 537, 101-110, Sep. 2017. DOI:10.1016/j.memsci.2017.04.060

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Keizo Nakagawa, Hiroharu Yamashita, Daisuke Saeki, Tomohisa Yoshioka, Takuji Shintani, Eiji Kamio, Hannah Theresa Kreissl, Shik Chi Edman Tsang, Shigeru Sugiyama, Hideto Matsuyama. "Niobate nanosheet membranes with enhanced stability for nanofiltration" Chemical Communications, 53(56), 7929-7932, Jun. 2017. DOI:10.1039/C7CC03911E

Enhua Xu, Motoyuki Uejima, Seiichiro Lenka Ten-no. "Full coupled-cluster reduction for accurate description of strong electron correlation" Physical Review Letters, (121), 113001, Sep. 2018. DOI: 10.1103/PhysRevLett.121.113001 Ayumi Yamashita, Takenao Ohkawa, Kenji Oyama, Chikara Ohta, Ryo Nishide, and Takeshi Honda. "Calf Weight Estimation with Stereo Camera Using Three-Dimensional Successive Cylindrical Model" Journal of the Institute of Industrial Applications Engineers, Vol. 6, No. 1, pp. 39-46, Jan. 2018. DOI: 10.12792/JIIAE.6.39 Go Matsukawa, Taisuke Kodama, Yuri Nishizumi, Koichi Kajihara, Chikako Nakanishi, Shintaro Izumi, Hiroshi Kawaguchi, Toshio Goto, Takeo Kato, Masahiko Yoshimoto. "A Low Power, VLSI Object Recognition Processor using Sparse FIND Feature for 60fps HDTV Resolution Video" IEICE Electronics Express, 14(15), 1-12, July 2017. (ELEX Best Paper Award 2017) DOI: 10.1587/elex.14.20170668 Makoto Nagata, Daisuke Fujimoto, Noriyuki Miura, Naofumi Homma, Yu-ichi Hayashi, Kazuo Sakiyama. "(Review paper) Protecting Cryptographic Integrated Circuits with Side-Channel Information" IEICE Electronics Express, 14(2), 1-13, Feb. 2017. DOI: 10.1587/elex.14.20162005

. " VLSI" C , J100-C(2), 82-

90, Feb. 2017.

Daisuke Watanabe, Michiyo Koyanagi-Aoi, Mariko Taniguchi-Ikeda, Yukiko Yoshida, Takeshi Azuma, Takashi Aoi. " cell-derived induced pluripotent stem cells from whole peripheral blood mononuclear cell culture" Stem Cells Translational Medicine, 7(1), 34-44, Jan. 2018. DOI: 10.1002/sctm.17-0021 Koichi Kitagawa, Reina Gonoi, Maho Tatsumi, Masahide Kadowaki, Takane Katayama, Yoshiko Hashii, Masato Fujisawa, Toshiro Shirakawa. "Preclinical development of a WT1 oral cancer vaccine using a bacterial vector to treat castration-resistant prostate cancer" Molecular Cancer Therapeutics, 18(5), 980-990, May. 2019. DOI: 10.1158/1535-7163.MCT-18-1105

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Koichi Kitagawa, Tsugumi Oda, Hiroki Saito, Ayame Araki, Reina Gonoi, Katsumi Shigemura, Yoshiko Hashii, Takane Katayama, Masato Fujisawa, Toshiro Shirakawa. "Development of oral cancer vaccine using recombinant Bifidobacterium displaying Wilms' tumor 1 protein" Cancer Immunology, Immunotherapy, 66(6), 787-798, Jun. 2017. DOI: 10.1007/s00262-017-1984-0 Ryo Ishida, Michiyo Koyanagi-Aoi, Nobu Oshima, Yoshihiro Kakeji, Takashi Aoi. "The tissue-reconstructing ability of colon CSCs is enhanced by FK506 and suppressed by GSK3 inhibition" Molecular Cancer Research, 15(10), 1455-1466, Oct. 2017. DOI: 10.1158/1541-7786.MCR-17-0071 Hiroyuki Ogawa, Michiyo Koyanagi-Aoi, Kyoko Otani, Yoh Zen, Yoshimasa Maniwa, Takashi Aoi. "Interleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells" Scientific Reports, 7(1), 12317, Sep. 2017. DOI: 10.1038/s41598-017-12017-y

Kenji Kutsuna, Janet Kiholm Smith, Richard L. Smith, Kazuo Yamada. "The Supply-Chain Spillover Effects of IPOs" Journal of Banking and Finance, 64, 150-168, 2016. DOI: 10.1016/j.jbankfin.2015.12.003 Xiaolu Bao, Sofia Johan, Kenji Kutsuna. "Do Political Connections Matter in Accessing Capital Markets? Evidence from China" Emerging Markets Review, 29, 24-41, 2016. DOI: 10.1016/j.ememar.2016.08.009 Yawen Jiao, Kenji Kutsuna, Richard L. Smith. "Why Do IPO Issuers Grant Overallotment Options to Underwriters? " Journal of Corporate Finance, 44, 34-47, 2017. DOI: 10.1016/j.jcorpfin.2017.02.011

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