Editorial Latest Treatment Option and Technology ...downloads.hindawi.com/journals/bmri/2014/203868.pdfEditorial Latest Treatment Option and Technology Advancement in Corneal and Ocular

EditorialLatest Treatment Option and Technology Advancement inCorneal and Ocular Surface Disease

Ciro Costagliola,1 Mark Batterbury,2 Harminder Singh Dua,3 and Leonardo Mastropasqua4

1Department of Medicine and Health Sciences, University of Molise, Via F. De Sanctis 1, 86100 Campobasso, Italy2Ophthalmology Department, St. Paul’s Eye Unit, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UK3Academic Ophthalmology, Division of Clinical Neuroscience, B Floor, Eye ENT Centre,Queens Medical Centre, University of Nottingham, Nottingham, UK4Eye Clinic, University “G. D’Annunzio” Chieti-Pescara, Chieti, Italy

Correspondence should be addressed to Ciro Costagliola; [email protected]

Received 21 October 2014; Accepted 21 October 2014; Published 28 December 2014

Copyright © 2014 Ciro Costagliola et al.This is an open access article distributed under theCreativeCommonsAttribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This special issue was focused on the current approaches inthe medical and surgical treatment of the most diffuse andimportant corneal and ocular surface diseases. In addition,the role of current available technologies in the diagnosisand follow-up of patients with ocular surface diseases wasalso included. We have invited many experts on this topic tohighlight the understanding of corneal diseases.

Different topics were exhaustively treated. This allowsimproving the readers’ knowledge on each theme, which isnowadays essential in the correct management of patients.

In detail, M. De Bernardo and coworkers described anddiscussed the different formulas to overcome the problemof calculating the intraocular lens power in patients thatunderwent corneal refractive surgery.

L. Mastropasqua and coworkers, focusing on glaucomasurgery, summarized the applications of time and spectraldomain anterior segment-OCT in the conjunctival blebassessment after filtrating surgery. The authors showed theutility of this technology in guiding the clinicians’ decisionsin the bleb management.

F. Semeraro and coworkers analyzed the potential et-iopathogenetic mechanisms involved in the epithelial ingrowth after Descemet’s stripping automated endothelialkeratoplasty, reviewing the literature, and discussing themostappropriate therapeutic approaches.

T. Liu and coworkers proposed a relatively safe designedstromal bed thickness to avoid the endothelial damage fol-lowing lamellar keratoplasty using an AllegrettoWaveLight 3FS200 femtosecond laser.

L. Ambrosone and coworkers evaluated the efficacy oftopical verbascoside-based liposomal eye drops in the healingof alkali corneal wound. The authors reported that thisapproach reduced significantly the first stage of the processof wound healing of the corneal epithelium.

P. Vinciguerra and coworkers compared the biomechan-ical effect, the riboflavin penetration and distribution in2 transepithelial corneal collagen cross-linking with ion-tophoresis (I-CXL), with standard cross-linking (S-CXL) andcurrent transepithelial protocol (TE-CXL), in rabbits. Theauthors found that I-CXL induced a significant increase incorneal stiffness as well as better riboflavin penetration whencompared to controls and TE-CXL, but not to S-CXL.

M. Lanza and coworkers evaluated the correlationbetween corneal biomechanical and morphological data inhealthy eyes, eyes that underwent myopic photorefractivekeratectomy (PRK), keratoconus affected eyes, and kerato-conus affected eyes that underwent corneal collagen cross-linking (CCC). The authors suggested suggest that cornealcurvature would have a greater influence on corneal defor-mation than corneal thickness.

L. Mastropasqua and coworkers quantified the effect ofsmall incision lenticule extraction (SMILE) on the cornealbiomechanics using Scheimpflug noncontact tonometer(CORVIS ST). The authors did not find significant modifi-cations in biomechanical properties after SMILE, suggestingthat this procedure could induce only minimal transientalterations of corneal biomechanics.

Hindawi Publishing CorporationBioMed Research InternationalVolume 2014, Article ID 203868, 2 pageshttp://dx.doi.org/10.1155/2014/203868

2 BioMed Research International

F. Semeraro and coworkers evaluated the efficacy of50% autologous serum eye drops in ocular surface diseasesnot improved by conventional therapy reporting that thistreatment effectively stabilized and improved signs and symp-toms in patients’ affected chemical burns, recurrent cornealerosion, neurotropic keratitis, and keratoconjunctivitis sicca.

A. Hill-Bator and coworkers reported a high cytopro-tective ability of trehalose-based eye drops both in viableepithelial corneal cell number after the desiccation and inpreservation of cellular functions.

Finally, D. Viswanathan and coworkers evaluated theefficacy of corneal collagen cross-linking for progressivekeratoconus in pediatric patients, reporting the treatment asan effective option in stabilizing the condition and reducingthe need for corneal grafting.

In summary, the papers published in this special issueconfirm the progress in both research and treatment ofcorneal and ocular surface disease.

The guest editors wish to thank all the authors of thisspecial issue for contributing the high quality papers. Wewould also like to thank the referees who have criticallyevaluated the papers.

Ciro CostagliolaMark Batterbury

Harminder Singh DuaLeonardo Mastropasqua

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Editorial Latest Treatment Option and Technology ...downloads.hindawi.com/journals/bmri/2014/203868.pdfEditorial Latest Treatment Option and Technology Advancement in Corneal and Ocular