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The ECG in healthy people 1 1 The normal cardiac rhythm 3 The heart rate 3 Extrasystoles 7 The P wave 7 The PR interval 11 The QRS complex 13 The ST segment 29 The T wave 33 The QT interval 42 The ECG in athletes 43 The ECG in pregnancy 47 The ECG in children 47 Frequency of ECG abnormalities in healthy people 49 What to do 49 For the purposes of this chapter, we shall assume that the subject from whom the ECG was recorded is asymptomatic, and that physical examination has revealed no abnormalities. We need to consider the range of normality of the ECG, but of course we cannot escape from the fact that not all disease causes symptoms or abnormal signs, and a subject who appears healthy may not be so and may therefore have an abnormal ECG. In particular, individuals who present for ‘screening’ may well have symptoms about which they have not consulted a doctor, so it cannot be assumed that an ECG obtained through a screening programme has come from a healthy subject. The range of normality in the ECG is therefore debatable. We first have to consider the variations in the ECG that we can expect to find in completely healthy people, and then we can think about the significance of ECGs that are undoubtedly ‘abnormal’.

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How to read an ECG

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  • The ECG in healthypeople

    1

    1The normal cardiac rhythm 3

    The heart rate 3

    Extrasystoles 7

    The P wave 7

    The PR interval 11

    The QRS complex 13

    The ST segment 29

    The T wave 33

    The QT interval 42

    The ECG in athletes 43

    The ECG in pregnancy 47

    The ECG in children 47

    Frequency of ECG abnormalities in healthypeople 49

    What to do 49

    For the purposes of this chapter, we shall assumethat the subject from whom the ECG was recordedis asymptomatic, and that physical examination hasrevealed no abnormalities. We need to consider therange of normality of the ECG, but of course wecannot escape from the fact that not all diseasecauses symptoms or abnormal signs, and a subjectwho appears healthy may not be so and maytherefore have an abnormal ECG. In particular,individuals who present for screening may wellhave symptoms about which they have not consulteda doctor, so it cannot be assumed that an ECGobtained through a screening programme has comefrom a healthy subject.

    The range of normality in the ECG is thereforedebatable. We first have to consider the variations inthe ECG that we can expect to find in completelyhealthy people, and then we can think about thesignificance of ECGs that are undoubtedlyabnormal.

  • 2The ECG in healthy people

    Sinus arrhythmia becomes less marked withincreasing age of the subject, and is lost inconditions such as diabetic autonomic neuropathydue to impairment of the vagus nerve function.

    THE HEART RATE

    There is no such thing as a normal heart, and theterms tachycardia and bradycardia should be usedwith care. There is no point at which a high heart

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    II

    Fig. 1.1

    THE NORMAL CARDIAC RHYTHM

    Sinus rhythm is the only normal sustained rhythm.In young people the RR interval is reduced (that is,the heart rate is increased) during inspiration, andthis is called sinus arrhythmia (Fig. 1.1). When sinusarrhythmia is marked, it may mimic an atrialarrhythmia. However, in sinus arrhythmia eachPQRST complex is normal, and it is only theinterval between them that changes.

  • other abnormalities on examination, and her bloodcount and thyroid function tests were normal.

    Box 1.1 shows possible causes of sinus rhythmwith a fast heart rate.

    1The normal cardiac rhythm / The heart rate

    3

    rate in sinus rhythm has to be called sinustachycardia and there is no upper limit for sinusbradycardia. Nevertheless, unexpectedly fast orslow rates do need an explanation.

    SINUS TACHYCARDIA

    The ECG in Figure 1.2 was recorded from a youngwoman who complained of a fast heart rate. She hadno other symptoms but was anxious. There were no

    Sinus arrhythmia

    Note Marked variation in RR interval Constant PR interval Constant shape of P wave and QRS complex

    Pain, fright, exercise Hypovolaemia Myocardial infarction Heart failure Pulmonary embolism Obesity Lack of physical fitness Pregnancy Thyrotoxicosis Anaemia Beri-beri CO2 retention Autonomic neuropathy Drugs:

    sympathomimetics salbutamol (including by inhalation) caffeine atropine

    Box 1.1 Possible causes of sinus rhythm with a fastheart rate

  • 4The ECG in healthy people

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.2

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    II

    Fig. 1.3

  • SINUS BRADYCARDIA

    The ECG in Figure 1.3 was recorded from a youngprofessional footballer. His heart rate was 44/min,and at one point the sinus rate became so slow thata junctional escape beat appeared.

    The possible causes of sinus rhythm with a slowheart rate are summarized in Box 1.2.

    1The heart rate

    5

    Sinus tachycardia

    Note Normal PQRST waves RR interval 500 ms Heart rate 120/min

    Sinus bradycardia

    Note Sinus rhythm Rate 44/min One junctional escape beat

    Physical fitness Vasovagal attacks Sick sinus syndrome Acute myocardial infarction, especially inferior Hypothyroidism Hypothermia Obstructive jaundice Raised intracranial pressure Drugs:

    beta-blockers (including eye drops for glaucoma) verapamil digoxin

    Box 1.2 Possible causes of sinus rhythm with a slowheart rate

    Junctional escape beat

  • 6The ECG in healthy people

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    II

    Fig. 1.4

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    II

    Fig. 1.5

  • EXTRASYSTOLES

    Supraventricular extrasystoles, either atrial orjunctional (AV nodal), occur commonly in normalpeople and are of no significance (Fig. 1.4). Atrialextrasystoles have an abnormal P wave; in junctionalextrasystoles, either there is no P wave or the P wavemay follow the QRS complex.

    Ventricular extrasystoles are also commonly seenin normal ECGs (Fig. 1.5).

    THE P WAVE

    In sinus rhythm, the P wave is normally upright inall leads except VR. When the QRS complex ispredominantly downward in lead VL, the P wavemay also be inverted (Fig. 1.6).

    A notched or bifid P wave is the hallmark of leftatrial hypertrophy, and peaked P waves indicateright atrial hypertrophy but bifid or peaked Pwaves can also be seen with normal hearts.

    In patients with dextrocardia the P wave isinverted in lead I (Fig. 1.7). In practice this is moreoften seen if the limb leads have been wronglyattached, but dextrocardia can be recognized if leadsV5 and V6, which normally look at the leftventricle, show a predominantly downward QRScomplex.

    If the ECG of a patient with dextrocardia isrepeated with the limb leads reversed, and the chestleads are placed on the right side of the chest insteadof the left, in corresponding positions, the ECGbecomes like that of a normal patient (Fig. 1.8).

    1Extrasystoles / The P wave

    7

    Supraventricular extrasystole

    Note In supraventricular extrasystoles the QRS complex and

    the T wave are the same as in the sinus beat The fourth beat has an abnormal P wave and therefore

    an atrial origin

    Early abnormal P wave

    Ventricular extrasystole

    Note Sinus rhythm, with one ventricular extrasystole Extrasystole has a wide and abnormal QRS complex

    and an abnormal T wave

    Ventricular extrasystole

  • 8The ECG in healthy people

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.6

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.7

  • 1The P wave

    9

    Normal ECG

    Note In both leads VR and VL the P wave is

    inverted, and the QRS complex ispredominantly downward

    Inverted P wave in lead VL

    Dextrocardia

    Note Inverted P wave in lead I No left ventricular complexes

    seen in leads V5V6

    Inverted P wave anddominant S wave inlead I

    Persistent S wave inlead V6

  • 10

    The ECG in healthy people

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.8

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.9

  • THE PR INTERVAL

    In sinus rhythm, the PR interval is constant and thenormal range is 120200 ms (35 small squares ofECG paper) (Fig. 1.9).

    A PR interval of less than 120 ms suggests pre-excitation, and a PR interval of longer than 200 msis due to first degree block. Both of theseabnormalities are seen in normal people, and willbe discussed further in Chapter 2.

    1The P wave / The PR interval

    11

    Dextrocardia, leads reversed

    Note P wave in lead I upright QRS complex upright in lead I Typical left ventricular complex in lead V6

    Upright P wave andQRS complex in lead I

    Normal ECG

    Note PR interval 170 ms PR interval constant in all leads Notched P wave in lead V5 is often normal

    PR interval 170 ms

    Normal QRScomplex in lead V6

  • 12

    The ECG in healthy people

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.10

    I VR V1 V4

    II VL V2 V5

    III VF V3 V6

    Fig. 1.11

  • THE QRS COMPLEX

    THE CARDIAC AXIS

    There is a fairly wide range of normality in thedirection of the cardiac axis. In most people theQRS complex is tallest in lead II, but in leads I andIII the QRS complex is also predominantly upright(i.e. the R wave is greater than the S wave)(Fig. 1.10).

    The cardiac axis is still perfectly normal when theR wave and S wave are equal in lead I: this iscommon in tall people (Fig. 1.11).

    When the S wave is greater than the R wave inlead I, right axis deviation is present. However, thisis very common in perfectly normal people. TheECG in Figure 1.12 is from a professional footballer.

    It is common for the S wave to be greater thanthe R wave in lead III, and the cardiac axis can stillbe considered normal when the S wave equals the Rwave in lead II. These patterns are common in fatpeople and during pregnancy (Fig. 1.13).

    When the depth of the S wave exceeds the heightof the R wave in lead II, left axis deviation is present(see Fig 2.26).

    1The QRS complex

    13

    Normal ECG

    Note QRS complex upright in leads IIII R wave tallest in lead II

    Normal ECG

    Note This record shows the rightward limit of normality of

    the cardiac axis R and S waves equal in lead I