Early metabolisms

Kate AdamalaAssistant ProfessorUniversity of Minnesota

Translationribosomes, cofactors, acyltrans-ferases

Membrane channels provide communication with the external environment.

Communication

Genes

tRNAs

Cholesterolmodulates membrane fluidity.

Phospholipids

Lipid bilayer membrane

Energy source and substrates

Small molecule substrates and energy components

Weiss, M.C., et.al.., 2016. Nature Microbiology, 1(9), p.16116.

Glansdorff, N., Xu, Y. and Labedan, B., 2008.. Biology direct, 3(1), p.29.

Lombard, J., López-García, P. and Moreira, D., 2012. Nature Reviews Microbiology, 10(7), p.507.

Suggested ReadingBar-Even, A., Noor, E. and Milo, R., 2011. A survey of

carbon fixation pathways through a quantitative lens. Journal of experimental botany, 63(6), pp.2325-2342.

Fuchs, G., 2011. Alternative pathways of carbon dioxide fixation: insights into the early evolution of life?. Annual review of microbiology, 65, pp.631-658.

Weiss, M.C., Sousa, F.L., Mrnjavac, N., Neukirchen, S., Roettger, M., Nelson-Sathi, S. and Martin, W.F., 2016. The physiology and habitat of the last universal common ancestor. Nature Microbiology, 1(9), p.16116.