8/16/2019 Drug Amlo,Diaze

1/2

Drug Indication: MOA Adverse reaction Nx Responsibility

Generic Name:Amlodipine

Brand Name:

Norvasc

Classicatrins:Calciu

m C!annel bloc"er

 #reatment o$ mildto moderate

%ypertension and

Angina

Amlodipine is a calciumc!annel bloc"ing agent

t!at selectively bloc"s

calcium ion re&ux across

cell membranes o$ cardiac

and vascular smoot!

muscle 'it!out c!anging

serum calcium

concentrations(

 It predomininantly act ont!e perip!eral circulation)

decreasing perip!eral

vascular resistance and

increases cardiac output

:*alpitation) +ig!t!eadedness)

!ypotension)nausea

Responsibility:Monitor B* $or t!erapeutic

e,ectiveness( B*

reduction is greatest

a$ter pea" levels o$

amlodipine are

ac!ieved $ollo'ing

oral doses(Monitor

$or -.- o$ dose/

related perip!eral or$acial edema t!at

may not be

accompanied by

'eig!t gain0 rarely)

severe edema may

cause

discontinuation o$

drug

8/16/2019 Drug Amlo,Diaze

2/2

Drug Indication: MOA Adverse reaction Nx Responsibility

Generic name:Dia1epam

Brand Name:

2allium

Classication:

Ben1odia1epin

Mgt o$ Anxiety and-tress

Binds to a specic subuniton t!e GABA receptor at a

site distinct $rom t!e

binding site o$ t!e

endogenos GABA molecule

"no' as allosteric site( #!e

GABA receptor is an

in!ibitory c!annel '!ic!)

'!en activated) decreased

neuronal activity(

Con$usion)amnesia)!angover)Nausea

• Monitor 2-especially t!e

respiration i$

I2

administration

• 3valuate

t!erapeutic

response)

mental state

and p!ysicaldependency

a$ter long

term use(