-
U. 5 DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE
Dr. Woodside Is NICHD Deputy Director; Known For Embryology
Studies
Dr. Gilbert L. Woodside has been named deputy director of the
National Institute of Child Health and Human Development. Since
last September, he has se1·ved as acting deputy director. Befol'e
that, he was NICIID Acting Di-rector, and from 1967 to 1!>74, he
was associate director for Extrn• mural Programs.
Dr. Woodside will be responsible for the analysis and
development of recommendations concerning ex-tramural programs, and
he will also coordinate activities with other Federal agencies and
scien-ti fie ;·ocieties.
Dr. Woodside oversees the Jn-stitutc's ~cientific review
activities, working with the NICHD Advisory Council, the NICHD
Board of Sci-entific Counselors, and the I nsti-tutc's Contract
Review Committee.
He joined XlCHD in 1964 as as~istant to the directo1· for
Scien-tific Program Planning and De-velopment, and as acting
p1·ogram director of the Reproduction Pro-gram. In 1965 he became
assistant Fcien ti fie di ,·er tor of extra mu ra I programs, and
in 1967 was ap-pointed associate dire
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December 16, 1975
nim~Record Published biweekly at Bethesda, Md .. by the
Editorial Operations Branch, Division of Public Information, for
the information of employees of the National Jnst it_utcs of
Health, Department of Health, Education, and Welfare, and
circulated by request to interested writers and to investi-gators
in t he field of biomedical and related research. The content is
reprintable without permission. Pictures are available on request.
The NIH Record reserves the right to make corrections, changes or
dele-gations in submitted copy in confonnity with the policies of
the paper and the Department of Health, Education, and
\.Velfare.
NIH Record Office . .. . ......... . Bldg. 31 , Rm. 28-03. Phone
49-62 125
Editor . . . . . . . . . . . . . . . . . • . . . . . . . . . . .
. . . . . . . . . . . Fronces W. Davis Associate Editor . ... , , .
, . , . .. , ... , , , ....... .... .. .. , . Fay Leviero Associate
Editor ... , . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . Heathe r Bonks
Staff Corresponde nts ADA, J udy Sternberg; CC, Susan Gerhold;
DCRT, Ruth Ketler; DRG, Sue Meadows; DRR, Jerry Gordon; DRS, Cora
M. Sult; F IC, George Presson; NCI, Ca1·olann Hooton; NEI, Bonnie
Friedman Spellane· NHL! Bill Sanders; NIAID, Krin Kolsky; NIAMDD,
Pat Gorman· NlClm' Daniel Taylor ; N IDR, Sue Hannon; NIEHS,
Elizabeth Y. James: NIGMS, Wanda Warddell; NIMH, Betty 7,ubovic;
NIKCDS Carolyn Holstein ; NLM, Frann Patrick. '
SPANISH HERITAGE DAYS ot NIH were celebrate d Dec. 3 and 4 withl
a program-La Fiesta-f ethnic dancing, singing ond music, includ-ing
flame nco. Dr. Isobel Caserta, executive secretory, lnte rarnerican
Commission on Women, OAS, dis-cussed the role of Latin-Arncricon
women. The court scene from Aida was performed by the Morionette
Theatre Company of Bogoto . The olmo,t life-si:i:e marionettes al,o
"did" dances from vorious ports of Co-lombio. The NIH Minority
Cultural Committee presented the program to commemorote
Sponish-Speoking Cul-tural Weck at NIH.-Photos by Ed Hubbard.
Dr. Steinfeld Named Dean, Medical College of Virginia
Dr. Jesse L. Steinfeld has been nsmed dean, Medical College of
Virginia. Dr. Steinfol
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THE NIH RECORO
Eckart Wipf, at NINCDS For 20 Years, Retires
Mr. Wipf reecived a DHEW Super-ior Service Aword for his
managerial abilities in support af his lnstitute's program.
Eckart Wipf, executive officer of the National Institute of
Neurological and Communicative Disot·ders and Stroke, is retiring
after 20 years with that Institute. He came the,·e in 1955-5 years
after it was established.
Mr. Wipf has been involved with the growth of 'the Institute,
working closely with the four Di-rectors who have served there
during his tenure.
One of Mr. Wipf's major tasks was the a(·quiring, planning, and
assigning space in Bldg. 36 when that facility was ready for
occu-pancy in 1968-69. He also helped obtain facilities for primate
col-onies in Puerto Rico, Patuxent, and Fort Detrick in Md., and a
t Gulf South, L3.
Trained Other Employees
Mr. Wipf also assisted in train-ing NIH employees in
administra-t ive jobs. He was on the Admin-istrative Training
Program for 3 terms where he served as chair-man for 1 term.
He also helped the Iranian gov-ernment to establish a personnel
train ing program in its central personnel agency.
In 1971, Mr. Wipf was awan.le:I a DHEW Superior Service Awanl.
He was cited for his ·• . . . man-agerial contributions in support
of NINOS medical programs, am! for participation in the
develop-ment and imprnvement of NIH administration, practices and
pro-cedures."
Mr. W ipf received his under-graduate degree at the University
of South Dakota, and his M.A. in public administration from the
University of Minnesota. He was aim awarded a Rockefeller
Schol-arship to the National Instilute of Public Affairs in
Washington, D.C.
He came to NIH-in the Per-sonnel Management Branch- in 1948,
after serving as adminis-
December 16, 1975
AU Offers Courses Here For Graduate Credits
The American University Col-lege of Continuing Education will
otr"er courses at NIH for graduate ereoit m public relations and
gov-ernment public information.
This coming semester, beginning the week of Jan. 19, two courses
will be offered: .Principles of Pub-lic Relations and Public
Relations and Government. Each cou,·se wiJI meet one night a week
for 2½ hours.
Credits may be applied towa.-cl a master of science in public
rela-tions or a graduate certificate in public relations or in
government public information.
The courses are open to all NIH employees who meet the
Universi-ty's entrance requirements. Regis-tration will be held on
Wednesday, Jan. 7, from 10 to 11:30 a.m., Bldg. 31, Room 6A-23.
For additional information about the p1·ogram and courses call
the College of Continuing Education, 686-2500. Further information
on the role of NIH in this program can be obtained from R. Anne
Ballard, Ext. 67526.
Italian Quartet Plays Jan. 11 The Quartetto Beethoven di
Roma, an Italian group that has won wide acclaim in Europe and
the U.S., consists of three well-known string players from the
Virtuosi di Roma who were joined by pianist Carlo Bruno in
1973.
They will appear Jan. 11 at 4 p.m. at the National Academy of
Sciences, 2101 Constitution Ave-nue, N.W., \.Vashington, D.C.
This is the third concert in the 1975-76 Chamber Music Series
sponsored by the F oundation for Advanced Education in t he
Sci-ences.
Admission is by ticket only.
Women Golfers Meet Jan. 13 The NIH Women's Golf Associa-
tion will hold an organizational meeting for the 1976 season
from noon to 1 p.m. on Tuesday, Jan. 13, in Bldg. 31, Conference
Room 4.
Individuals at all levels may join. R&W membership is
required.
The new season starts in April and runs through September. Those
who are interested in join-ing but cannot attend the meeting may
contact Roberta Seward, Bldg. 10, Room 10S-224, Ext. 63101.
trative assistant at the Veterans Administration in St. Paul.
Mr. Wipf was a PMB position classi-fier and personnel assistant; 2
yea1·s later, he became a classifi-cation officer. He remained
there until his NINCDS appointment.
At a farewell party given to him by co-workers and colleagues,
Mr. Wipf said his retirement plans include traveling and vis-iting
the fam ily's beach house on Chesapeake Bay.
For Happy Holidays-Be Careful, Lock Up!
It's holiday time- time for em-ployees to take special
precautions to protect their p ,·operty from the time they an-ive
on the reservation until they leave for the day. The Security
Management Brnnch sug-gests:
• After parking yom· car, roll up the windows and lock it.
Re-r,,orn attractive items that might encourage thieves to break
into the car.
Good Advice!
• Keep valuables out o.f sight or locked in the trunk, and make
sure your car is locked before you leave it.
• Can-y key~, wallets, and other small valuables with you,
rather than leaving them in a coat on a 1·ack. Women should carr~,
their purses with them at all times or place them in a locked
cabinet.
• Do not leave coffee f unds or other money in locked or
unlocked desk drawers. Lock money in a safe.
• Transistor radios, TV's, port-able tape recorders, portable
cal-culators, and ~ameras should be kept under lock and key.
• Do not leave the office or laboratory unattended and un-locked
at any time during working hours, lunch, or coffee breaks.
• Don't be gullible. Check up on strangers and don't leave them
alone in an office or l aboratory area. Every day several reports
arc received of suspicious stran-gers in hallways, offices, labs,
and other areas.
Sometimes they arc carrying papers, envelopes, fluorescent light
fixtures, or air vent covers, giving the appearance of messengers
or repairmen. Others pretend to be looking for a person in the bui
ld-ing.
Often these incidents are re-ported too late or the descriptions
are vague. Observe any strangers carefully in order to furnish a
good description, and report the matter to the guard offiee without
delay. It Only Takes Seconds
• When leaving the work area during business hours or at the end
of the day, see that everything is properly ~ecured.
A purse, radio, or other attrac-tive, moveable item could easily
be snatched in a matter of a few seconds, as often happens when
people leave their desks intending to return within a few minutes,
believing that nothing can be stolen in the inter im.
SMB hopes your holidays will be happy, but if a theft occurs,
fol-low the procedures in item 40, page 247 in the yellow pages of
the NIH T elephone and Service Directory.
Page 3
New Health Plan Rates To Be Effective Jan. 4
The "Open Season'' for the Federal Employees Health Bene-fits
Program will end on Dec. 31.
Enrollments or changes in en-1 ol lment made during this "open"
period, effective Jan. 4, will be reflected in checks on J 2 11.
27.
The Civil Service Commission has notified the Employee
Rela-tions and Recognition Branch, D:F M, that the 1976 biweekly
rates employees will pay for enrollment in the four major health
plans are:
1975 1976
GROUP HEAL TH ASSOCIATION OF WASHINGTON, D.C.
Selj High option Low option
Family High option Low option
$7.00 3.16
18.14 8.89
$9.63 3.93
24.97 11.38
INDEMNITY BENEFIT PLAN (Aetna)
Self High option Low option
Family High option Low option
3.88 1.59
9.77 3.93
SERVICE BENEFIT PLAN (Blue Crass-Blue Shield)
Selj H igh option Low option
Family High option Low option
5.40 1.02
12.88 2.50
6.71 2.14
15.33 5.31
8.77 1.02
20.01 2.95
UNIVERSITY AFFILIATED HEALTH PLANS, INC. OF WASHINGTON,
D.C. (plan has only one option)
Self 4.61 Family 17 .82
4.98 17.37
As soon as the leaflets entitled 1 .976 Biweekly 1-leu.lth
Benefits Rates becomes available, they ,viii be distributed to all
employees. Until then, employees should clip and attach this chart
to t heir 1976 plan brochure.
To obtain rates on other health plans, employees may conte.ct
their per,onnel office.
NIH Symphony to Play in CC The NIH Symphony will start
its seventh season here with a conce1·t on J an. 21, at 8 p.m.,
in the Clir.ica l Center's 14th floor •. uditorium. Rog·er Oliver
is the t ymphony's conductor.
The orchestra will play l\Ioz,11·t's Overture to Don Giovanni:
Men-delssohn's Scotch Symphony; the Gavotte and Musette from Bach's
Third English Suite, and The Fruhlingsstimmen Waltz by Strauss.
Musicians interested in joining the symphony may contact Charles
Shaw, manager, Ext. 63085.
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Page 4
FREDRICKSON'S NIH (Continuecl froni Page 1)
gressional directives.
As NIH approaches the 1980's with periods of predictably slow
program growth, Dr. Fredrickson felt there should be cettain steps
taken to imp1·ove the processes of priority-setting in biomedical
re-bearch-establishment of a mean-ingful advisory apparatus to
sup-port the NIH Director and speci-fic, though limited,
authorization for the Director to rep,·ogram funds between
appropriations.
Exploins Influence
When asked his reaction to the position taken by certain
econo-mists that increasing funds fo1· biomedical research is not
par-ticularly cost effective, Dr. Fred-rickson pointed out that
while it is unlikely that biomedical re-search per se will produce
further dramatic effects on infant mortal-ity 01· on mean survival
rates, it will have considerable further in-fluence on dec1·easing
premature death and on improving the quality of life of all
ages.
He stated, however, that medical care alone will not take care
of all premature mortality or guar-antee the quality of life.
Pollution, poor housing, crowding of popula-tions, and other
socio-economic causes of disease must be dealt with as well.
Extroordinary Advonces
The chronic diseases having cul-tural as well as molecular bases
are difficult to eradicate with the profound success that has
marked the conquest of some infectious diseases.
Nevertheless, the advances in biomedical knowledge in two
dec-ades of expanded research have been truly extraordinar)•. The
en-lightenment is cer tain to be con-tinued and will have effects
on man's remaining disease problems.
In time, most of the big prob-lems of chronic disease will be
eliminated. The objective should be JJot so much to extend greatly
the current life span as to im-pl'Ove its quality du1·ing the
pro-cess of aging.
Effective Me thods Esse ntial
Biomedical advances, he said, seem essential to the survival of
the species. If we arc to regulate ou1· numbers in a rational way
we will have to contl'Ol fertility by morn effective methods than
we now have.
In the endless seHrch for new sources of energy, food, and
eco-nomic growth we will continue to tamper with our ecology. Our
ability to keep those environmental changes within the limits of
hu-man tolerance will mean forever pushing forward the edge of
knowledge.
becember 16, 1975 TH E NIH RECORD
VIEWS EXPLAINED Dr. Fredrickson aim noted that
biomedical research is the main source for continuing reform of
medical care. H is, therefore, still a major determinant of the
ulti-mate cost of health care.
Statistics Quoted
Funds fo1· biomedical research have fallen from 4.8 to 4.2
percent of the health dollar. He said so-ciety would resist a
further de-cline below this figure because there appea1·s to be no
other way to change the substance of medical care.
In response to a question as Lo his views on Congressional
man-dHtes which appear to have ex-tended the traditional role of
NIH, O,·. Fredrickson likened NIH to a cell with a bilayer- an
inner and outer membrane. The inner mem-brane defines functions to
be sup-ported out of funds for research, and the outer layer is the
limit of NIH responsibilities.
Gap Widened
The gap between these two boundaries has shifted back and forth
considerably in the history of the NIH, he noted, and at the
present time there are great dif-ferences in this gap among the
different Institutes. As an ex-ample he stated that the control and
demonstration programs of NCI and N HLI reach to the outer
boundary.
NIH will continue to have some role in certain activities that
are not strictly research, such as con-trol and demonstration, but
to protect the pl'imai·y mission of NIH, he emphasized that it is
essential that the,e be conducted under separate funding and
ex-plicit limitations.
Involve me nt Ne cessary
NIH's involvement in the dis-semination of new knowledge or
techniques becomes necessary when there is no other agency for this
purpose, and when there is expert agreement that extension or
dissemination is worthwhile and is to be undertaken in a
sci-entific manner, he said.
Dr. Fredrickson suggested that a strong commitment to clinical
testing must be maintained, but that we must know when not to
engage in these activities since they represent a great dilution of
resources.
When asked what he would pro-pose as a new disseminating body,
Dr. Fredrickson said he felt that some way must be found to re-
In making theories always keep a window open so that you can
throw one out if nece-,sary -Bela Schick.
Dr. Fredrickson Comments On Clinical Center Role
During questioning of Dr. Fredrickson by the P1·esident's
Biomedical Research Panel about the role of the Clinical Center, he
said that the Clin-ical Center is in serious need of
modernization.
The Clinical Center has run out of space for clinics; the
operating rooms and intensive care unit are inadequate; di-agnostic
X-ray is g1·owing "out of its skin,'' and the clinical laboratory
is greatly overcrowded.
While the budget has gone up, the staff is going down. There has
been a decrease in support of positions, particu-larly in nurf3es
and in train-ing positions. Professional salary levels am too low
and (ar out of line with the mar-ket place.
The Clinical Center, Dr. Fredrickson said, serves as a constant
reminder to investi-gators at NIH of the practical problems in
health and med-icine.
organize the medical system, per-haps to involve the
universities and the medical schools in this effort.
I n reply to a question as to whether opening peer review to the
public would impair the effec-tiveness of t he process, Dr.
Fred-rickson commented that no one know~ what would happen but he
is concerned that the viabil ity of the peer review process be
pro-tected.
He can only speak of the peer review system in "superlatives,"
he added, but continued vigilance is essential.
SYNTHESIS (Continued from Page 1)
actively-labeled compounds in lab-oratories equipped with
radioac-tive-counting facilities.
The investigators have also shown that the new compound, which
is an analogue of the ac-cumulating sphingomyelin, is use-ful for
prenatal diagnosis of Nie-mann-Pick disease.
It has also been used success-fully to identify an unaffected
car-rier of the defective gene in i,tero. They reported their
findings in the Sept. 25 issue of the New England Jowrnal of
Medicine.
Since t he middle 1960's Dr. Brady and his colleagues have made
many important discoveries concerning the chemical nature of these
lipid storage diseases.
Their findings have led not only to diagnostic tests for these
dis-eases but also to an experimental enzyme replacement therapy
which has shown promise in early tests on patients with two of
these dis-orders.
Also associated with Dr. Brady in this study were Sue R. Hibbert
and Dr. Peter G. Pentchev.
He alth Statistics Center Gives Decennial Life To bie Data
A 20-year-old American can ex-pect to live another 53 years, and
a 62-year-old white male can ex-pect just unde1· 17 years of life,
according to U.S. Life Tables re-cently published by the National
Cente1· for Health Statistics.
The figure~ for the period 1969-71 are the results of a
decennial study calculated from 1970 Cen-sus data.
Black persons have shorter life expectancy than do whites; black
males have the shortest expec-tancies of all.
Dr. Carl Kupfer, NEI Director ond Combine d Federol Campaign
vice-choirmon for NIH (left), congrotulotes Dr. Wilford Nusser, N
EI Scientific Progroms Bronch chief and CFC coordinator, on the
progress of the CFC drive as Fron Cryon updotes the CFC progress
chart. As of Dec. 11 , NIH had reoched more thon 90 perce nt of its
quoto with contributions totaling $179, 319, on overa ge of $34
.76. The drive hos been extended until Dec:. 18--officials hope NIH
will reoch the CFC goal by thot time ond increase ih present 53
percent porticipotion rote.
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THE NIB RECORD December 16, 1975 Page 5
Exhibit on Retinopathy Wins Prize; Designed by NEI, DRS
The National Eye lnstitute's exhibit at the recent American
Academy of Ophthalmology and Otolaryngology meeting in Dallas won
the second award in ophthal-mology-a silver medal-among 60
scientific exhibits.
N EI's "Diabetic Retinopathy Study-A Nationwide Clinical Trial"
was planned and designed t.y the Institute's Office of Pro-gr~m
Planning and Scientific Re-pol'ting and the Medical Arts and
Photography Branch, Division of Re~earch Services.
The exhibit included photo-graphs, graphics, a sound color
movie, and a narrated slide pre-sentation to explain the
NEI-supported nationwide Diabetic Retinopathy Study.
The movie follows a typical pa-tient from initial examination to
8 months of posttreatment. It will soon be available to medical and
public health schools, volunta1·y health agencies, and other
01·gan-izations.
It will also be used as an orien-tation for those participating
in futul'e NEI-supported clinical trials.
FAES Schedule Available The schedule for spring courses
of the Graduate Progrnm at NIH is now available. The evening
courses, sponsored by the Founda-tion for Advanced Education in the
Sciences, Inc., are given on the campus.
Medical subspecialty review courses that are being offered
in-clude MEDI 604-medical oncology; MEDI Gl0-internal medicine (a
continuation of the .fall course); MEDI 612-infectious disease, and
MEDI 614-clinical hematology.
Tuition is $22 per semester hour; courses may be taken for
c1·edit· or audit. Students now en-rolled in courses that continue
through the spring semester must reregister. Students whose courses
will be financed by the Govern-ment should apply immediately to
their administrative offices for this assistance.
Classes will begin Feb. 9. Regis-ter by mail now through Jan.
16-or register in person from Jan. 29 through Feb. 4. Schedules may
be picked up in the school office, Bldg. 10, Room Bl-L-101, or call
Ext. 65272 to have one sent.
Normal Male Baboon Infant Is the Result Of Successful Embryo
Transfer in Texas
The first step toward application of embryo transfer techniques
to the production of nonhuman primates for biomedical research was
made with the successful transfer of an embryo (fertilized egg)
from one female baboon to another.
The "foster mother" carried the fetus from the fifth day after
its conception until the baboon infant was delivered by Caesa1·ean
section following the normal gestation period.
The transfer was made March 20, 1975, at Southwest Foundation
for Research and Education in San Antonio, Tex. The male infant-the
first nonhuman pri-mate infant known to be produced by embryo
transfer-was delivered Sept. 5, weig·hed 875 grams (30.6 ounces),
and appears entirely normal.
The study was supported by the Division of Research Resources
through its Animal Resources Dr. Kraeme r holds the perfectly
nar-Program. The principal investi- mat 8-week-old baboon produced
by gator on this project was Dr. successful e mbryo transfe r
techniques Duane C. Kraemer, associate pro- at the Southwest
Foundat ion for Re-fessot· in the College of Veterin- search and
Education in Son An-ary Medicine, Texas A & M Uni- tonio, Te
x., under o grant by ORR. versity. Dt·s. Gary T. Moore and Martin
A. Kramen were co-in-vestigators.
The embryo was removed from the donor animal using a surgical
flushing technique, and the trans-fer was made to the recipient
uterus following surgical exposure of the uterus.
Dr. Kraemer, the first to apply embryo transfer techniques to t
he commerical production of purebred cattle in August 1971, reports
that procedures used in the baboon
are very similar to t hose now used by companies around the
world to increase the number of offspring from outstanding
cattle.
This research has potential for improving human health by
in-creasing the productivity of indi-vidual nonhuman primates which
possess special genetic character-istics that make them
particularly valuable as models for t he study of human
disease.
One example of possible future
Dr. Storrs Given Award for Developing Armadillo As Leprosy Study
Model; Research Supported by ORR
Dr. Eleanor E. Storrs, director of comparative biochemistry and
mammalogy at the Gulf South Re~earch Tnstitute, in New Iberia, La.,
was presented with the Grif-fin Award b)• the American Asso-ciation
for Laboratory Animal Science at their 2Gth annual meet-ing held a
month ago in Boston. Receives Plaque, Honorarium
That award, the oldest of the &wards presented by AALAS, is
given annually for the most sig-nificant contributions to the
ad-vancement of laboratory animal science and medicine. The winne1·
receives a bronze plaque and an honoral'ium of $500.
Dr. Storrs developed the arma-dillo as the first unaltered
animal model for the study of lepromatous leprosy-an achievement
consid-ered by many researchers to be the most important
development in leprosy research in the past 100 years.
Dr. Storrs' studies and colony development of the armadillo have
been supported by the Division of Research Resources since
1969.
In developing the armadillo as a model for the study of human
diseases, Dr. Storrs has investi-gated their cell-mediated immune
system, hematology, enzyme and amino acid levels, and reproductive
system. She has also demonstrated that the armadillo is a valuable
animal for monitoring the envir-onment for insecticides.
ORR-Supported Group Cite d
Another ORR-supported g 1·oup from Kansas State University was
presented with the 1975 AALAS Research Award for the best pa-per
published in Labomlory Ani-mal Science. Drs. James E. Woods and
Emerson L. Besch are the co-authors of the paper-Influence of Group
Size on Ileat Dissipation from Dogs in a Controlled E
n-vironment.
Their study suggested that group size may affect the meta-
application of this embryo trans-fer technique is to produce
specific strains of nonhuman primate~ for biomedical research on
such human diseaees as atherosclerosi~, d ia-betes, and cancer.
Thesaurus on Medical, Health Sciences Avoilable from DRG
The 1975 Medical and Health Related Science Thesnurns is now
available in limited supply.
The The.rnurus is the subject heading list of the Research
Grants Index, a classified index of research projects supported by
PHS. It is also an integral com-ponent of CRISP-Computer Re-trieval
of Information on Scien-tific Projects-this data pertains to
research grants and contracts.
Many scientists consider Or. Storrs' och ieveme nt to be the
mast impor-tont development in le prosy research in the past 100
years.
bolic rate of dogs caged individu-ally in a thermally neutral
envir-onment, independent of the effects of cage size and
ventilation rate.
NIH Visiting Scientists I Program Participants
11/ 24- D1·. Ann Tei-Sen Ma Cheng, China, Laboratory of
Pa-thology. Sponsor: Dr. Elizabeth W. Chu, NCI, Bg. 10, Rm.
2Al5.
11/ 24-Dr. Rafael Martin, Spain, Laboratory of Biochemis-try.
Sponsor: Dr. T. C. Stadt-man, NHLI, Bg. 3, Rm. 103.
11/ 25-Dr. Kohji Nomura, Ja-pan, Laboratory of Cerebral
Me-tabolism. Sponsor: Dr. Marian W. Kies, NIMH, Bg. 36, Rm.
1A27.
11/ 26-Dr. Pran Krishna Chak-rabartty, India, Laboratory of
Pathophysiology. Sponsor: Dr. Pradman Qasba, Bg. 10, Rm. 5B45.
3 Countries Represented
11/ 30-Dr. Surenclra Bhatnagar, India, Laboratory of Chemical
Physics. Sponso1·: D1·. Ulrich Weiss, N IAMDD, Bg. 2, Rm.
Bl-22.
12/ 1- Dr. Luigi Paolo Ruco, Italy, Tumo1· Antigen Section.
Sponso1·: Dr. Monte Meltzer, NCI, Bg. 37, Rm. 2C26.
12/1-Dr. Ajit Kumar Thakur, India, Laborntory of Theoretical
Biology. Sponsor: Dr. Charles DeLisi, NCI, Bg. 10, Rm. 4B58.
12/1-Dr. Sung Jin Uhm, Korea, Analytical Chemistry Unit.
Spon-sor: Dr. Larry K. Keefer, NCI, Bg. 37, Rm. 1E22.
In the near future, intramural programs will be included.
Data for CRISP, and copies of the 'l'hesaurus and l nde:x:, may
be requested from the Research Docu-mentation Section, SAB, DRG,
Westwood Bldg., Room 3A-03, Ext. 67543.
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Page 6
Am. Heart Assoc. Meets In Anaheim; 10 Reports Given by NHLI
Staff
More than 10,000 physicians, scientists, and allied health
pro-fessionals participated in the 48th Scientific Sessions of the
Ameri-can Heart Association in Anaheim, Calif., Nov. 17-20.
The sessions, characterized by AHA President, Dr. Elliot
Rapa-port as "the most comprehensive forum available in the world
for the exchange of cardiovascular in-formation," featured 576
reports of original research investigations presented during as
many as e ight simultaneous sessions on basic, ex-perimental, and
clinical research.
The various sessions covered such diverse cal'diovascular fields
as myocardial isotope imaging, echocardiography,
electrocardJog-raphy, angiography, cardiovascu-lar surgery, cardiac
pacing, exer-cise and exel'cise testing.
Other topics included high blood pressure research,
cardiovascular drugs, cholesterol metabolism, lip-oproteins,
arteriosclerosis, myo-cardial infarction, electrophysiol-ogy,
ventricular function and he-modynamics, myocardial contract-ility,
peripheral circulation, card-iovascular nursing, stroke, shock,
epidemiology, community pro-grams, thrombosis, and hemosta-sis,
among others. NIH'ers Present
The scientific reports-selected from among 2191 abstracts
sub-mitted-included 10 presented by National Heart and Lung
Insti-tute scientists and program staff members, aud many more by
NHLI grantees and research contractors.
Dr. Eugene M. Bl'aunwald, ller-sey Professor and head,
depart-ment of medicine, Harvard Med-ical School, at the Peter Dent
Brigham Hospital, Boston, de-
livered the Lewis A. Conner Me-morial Lecture.
Speak ing on Function and Pro-tection of the l s-chemic
Myoca1·d-ium, Dr. Bi·aun-wald described en-couraging results of
experimental ef-
Dr. Brounwold forts to limit the extent o.f heart-muscle injury
and death following a heart attack.
Head of the N lILI Cardiology Branch from 1958 to 1968, Dr.
Braunwald also served as the In-stitute's clinical director and i~
currently a member of the Na-tional Heart and Lung· Advisory
Council.
Reviews of various cardiovascu-lar specialties were pl'esented
in clinical sessions concurrent with the research reports, and
during the evening postgraduate semina rs and "how to" sessions
were given by invited lecturers and panelists.
December 16, 1975
VIEWS OF BLOG. 6 EAST- from inside ond out- now include
construction of o basement level and two floors designed to add
2,000 square feet of laboratory space. The construction, started
May S ond scheduled for com-pletion in April 197 6, has been
delayed by strikes and s hortages of materiols.
Patients at CC Enjoy Wide Variety Of Activities During Holiday
Month
For Clinical Centei; patients and their guests, the month of
December is filled with an endless variety of activities to
celebrate the holiday season.
This year, the younger children met on Dec. 4 with Santa and his
helpers at the "North Pole" in .iVIontgomery Mall to pose for
pic-tures and whisper long lists of fa-vorite toys fo1· Christmas.
In the evening, a variety show was pre-sented by the Scottish Rite
Ma-sons.
Shopping sprees, Christmas bin-go, and arts and crafts pursuits
enabled many patients to make last minute purchases or add
fin-ishing touches to a special gift.
Traditional and seasonal songs were presented by the U.S. Air
Force Singing Sergeant.~ in a holi-day concert Dec. 11.
A real treat for everyone was the visit to the Poinsettia Show
at the U.S. Botanical Gardens on Dec. 13.
On the same day, t he children also enjoyed a Christmas party
sponsored by the Clifton Park Cit-izens Association, and this past
Sunday, Dec. 14, a Pl'Otestant
-
THE NIH RE CORD
Lois P. Me ng, public information specialist in the Office of
Communcat ions, O D, received an EEO Specia l Achievement Award on
Nov. 26 from Raymond Jackson (I), NIH EEO Director, and Storm
Wholey, NIH Associate Director for Communications. Mrs. Meng wa s
cited for "esta blishing the format for the EEO Report" a nd
communicat ing " the concerns ond needs of minorit ies ond wome n
.•. to the NIH workforce . . . contributing immeasurably toward
better understanding ond occeptonce of equal opportunity."
NCI Sponsors Seminar on Anticancer Nitrosoureas NCI's Division
of Cancer T1·eat-
ment sponsored a seminar this week on the nitrosQureas, a new
chemical class of anticancer drugs. Two of these drugs-BCNU and
CCNU-may soon be commercially available. They were developed in an
NCI-sponsored program at the Southern Research Institute in
Birmingham, Ala.
Designed for Physicians The seminar, held at the Wash-
ington Hilton Hotel, was the seventh in a series designed to
acquaint practicing physicians with the uses and side effects of
anticancer drugs as they become candidates for use in standard
medical practice.
Dr. Vincent T. DeVita, Jr., di-rector, and Dr. Stephen K.
Carter, deputy director of the Division of Cancer Treatment,
moderated the 2 days of scientific sessions.
BCNU and CCNU wi.11 be mar-keted under the trade names of BiCNU
and CeeNU, respectively, by Bristol Laboratories, Syracuse, K.Y.
BCNU is given intraven-ously; CCNU is taken orally. Brain Tumors
Treated
I n NCI-supported clinical studies, the drugs have been found
useful for treating brain tumo,·s-both primary and metastatic-and
for treating Hodgkin's disease and other brmphomas. BCNU in
com-bination with P1·ednisor.e, an estab-lished anticancer drug, is
active against multiple myeloma.
The activity against brain tu-mors is unique for anticancer
drugs. The brain has long been considered a hideaway for cancer
cells because drugs were unable to penetrate the so-called
''blood-brain barrier" layers of lipid-rich protective m:mbt·~nes
surrounding
the brain. The nitrosoureas are lipid soluble and thus slide
through the barrier.
An afternoon session of the seminar was devoted to a work-shop
on malignant gliomas, a par-ticularly virulent form of brain
cancer. Dr. Michael Walker, di-rector of NCI's Baltimore Cancer
Research Center, discussed a study b~, the Brain Tumor Study Group.
Glioma patients treated with BCNU and/ or radiation therapy
following su rgery lived longer than patienls who had surgery
alone.
Effective in Bowel Cancer
Another workshop focused on advanced large bowel cancer.
Methyl-CCNU, a chemical relative of CCNU, has been found active
against colon canter. Dr. Charles Moertel, who conducted an
NCI-supported clinical study at the ~lbyo Clinic, reported that
Methyl-CCNU, in combination with 5-fluorouracil-the standard drug
used in treating advanced large bowel cancer-and vincristine, is
superio1· to any drug regimen tested ~o far.
The total dose or BCl\'U or CCNU that a cancer patient can
receive is limited by a suppres-sion of white blood cell and
plate-let precursors in the bone mar-rnw-the major sid
-
Page 8 December 16, 1975 THE Nill RECORD
There Are a Number of Reasons Why NIH'ers Should Donate to
PEF-and They're All Good
During surgery or other critical periods of hospitalization for
Clinical Center patients, NIH physicians often request a relative
to remain nearby. For the patient's family, the expense of staying
in Bethesda overnight may be prohibitive.
The Federal Government pro-vides medical and hospital care at
NIH without charge, but funds appropriated for this care may not be
used for other expenditures.
To assist patients in financial difficultie~, the Social Work
De-partment-headed by Barbara A. Murphy-adminisLers the NIH Patient
Emergency Fund- that fund is supported by voluntary
contributions.
Last year, $45,000 was needed to help CC patients in non-medical
financial emergencies. This year, $55,000 has already been
spent.
Because of the serious shortage of emergency funds, CC social
workers are forced to limit several forms of a id-such as weeklv
al-lowances to some patients. ·
Ms. Murphy has asked N IH em-ployees to donate to the Patient
Emergency Fund. Contributions may be sent to the CC Social Work
Dept., Bldg. 10, Room lN-254.
A visitor from home reads a favorite book. That in itself is
consideerd therapy, a nd is often recommende d by NIH
physicians.
Also, instead of exchanging greeting cards with other
employ-ees, NlH'ers may contribute to the fund through the Davis
Plan by sending donations to Bldg. 31. Room lA-17.
Children at the CC (like the one above) eagerly await visits by
their fam-ilies. Many such visits are possible anly with Patient
Emergency Fund anistance.
Often a physician will ask parents of CC patients to attend
discussions regarding the patient's illness. Without PEF fu nds,
same families may nat be able to afford the trip ta Bethl!sdo ,
Labor-HEW Appropriation Bill Goes to White House
As the R ecord went to press, the Senate and House ap-proved the
conference report on the Labor-HEW appropria-tion bill for i;,36.1
billion and sent it to the White House for the Pi·esident's
signature.
The appropriation for NJ H is $2.178 billion.
Blood Bonk, Red Cross Join Forces, Seek Donors At Westwood on
Jan. 9
The Clinical Center Blood Bank r.nd the Montgomery County
Chap-ter of the American Red Cross will hold a joint blood drive at
the Westwood Bldg. to recruit as many new donors as possible, and
to m,1ke it convenient for 1·egular NIH donol"S there to clonat.e
during the ho! iday season. NIH Receives Cre dit
The NIH Blood Bank will re-ceive full credit for all units of
blood collected. New donors re-cruited during this drive will be
integrated in the reg4lar donor system at the CC.
To become a volunteer blood donor at the \Vestwood Bldg.,
Con-ference Room D, between 9 :30 a.rn. and 3:15 p.m. on Friday,
Jan. 9, please contact Jimmie L. Driscoll, Bldg. JOA, Room lE-33,
Ext. (;1048, or Ki,·k Weaver, Westwood Bldg., Room 509, Ext.
67085.
DH EW Management Intern Applications Now Being Accepted
Applications are now being ac-cepted from qualified employees of
the Department for the DHEW Management Intern Program.
Deadline for applications is Feb. 14, 1976.
This 3-year internship consists of four 9-month rotational
assign-ments in different management areas within at least three
HEW agencies.
Interns enter the program at the GS-5 or GS-7 levels, and upon
successful completion can qualify for positions at the GS-11 or
GS-12 levels.
Employees are eligible to apply if:
• By Feb. 14 they have served continuously for 1 year in a
career or career-conditional appointment.
• They are a GS-4 or highe1·. • They will be eligible for
GS-5
or GS-7 when the program begins in July 1976.
Other requirements considere
