Dr. Hani's Alhadrami CV - MEMBS. Hani's Alhadra… · -Anwarul Hasan, Amir Sanati-Nezhad, ... Hani A. Alhadrami, Ali Khademhosseini ... and Gel Electrophoresis by using both polyacralmyied

D R . H A N I A L H A D R A M I

Name: Dr. Hani Abdullah Anber Alhadrami

Work Address: Faculty of Applied Medical Sciences, Centre

of Excellence In Genomic Medicine Research &

Centre of Innovation In Personalised Medicine

King Abdulaziz University,

P.O. Box. 80402, Jeddah 21589, Saudi Arabia.

Email address: [email protected]

Tel: +966(012) 6952000 Ext. 25586

Mobile: +966(0)505545275

Education and Qualifications 2008-2011 PhD in Biotechnology, College of Life Sciences and Medicine,

University of Aberdeen, United Kingdom. Project Title:

Development and Applications of Mutagenicity and Carcinogenicity

Bioassays for Human Health Risk Assessment.

2006-2007 MSc in Microbiology & Biotechnology (with Commendation),

College of Life Sciences and Medicine, University of Aberdeen,

United Kingdom. Project Title: Assessing the Potential of Flow

Bioreactors to Minimise Human Health Impacts of mutagenic

chemicals.

1999- 2004 BSc (Honours) in Medical Technology, Faculty of Applied

Medical Sciences, King Abdulaziz University, KSA. Project Title:

Platelet Aggregation and Adhesion in Patients Suffering from

Ischemic Heart Disease Using Flow Cytometer.

Work Experience June-Sep 2014 Visiting Professor at Harvard Medical School and

Harvard-MIT Division of Health Sciences and

Technology, Massachusetts Institute of Technology,

Cambridge, Massachusetts 02139, USA.

Faculty of Applied Medical Sciences, King Abdulaziz University, P.O.Box 80402, Jeddah 21589, Saudi Arabia. Email: [email protected]

mailto:[email protected]



Nov 2013-May 2016 Chairman of Health Information

Technology Department, Community College

Jeddah, King Abdulaziz University, Saudi Arabia.

July 2011-present Assistant Professor in Biotechnology and Molecular

Genetics, Department of Medical Technology, Faculty of

Applied Medical Sciences, King Abdulaziz University, KSA. The

work involves teaching and lecturing for postgraduates and

undergraduate students, preparing and teaching practical

sessions, conducting tutorial sessions, setting-up theoretical

and practical exams, and marking students exams. The work

also involves the academic and research supervision for

honour and master students. Taught Courses are: Biotechnology,

Genetics, Molecular Biology, Cell Biology and Biochemistry.

Aug 2013-present Researcher & Assistant Professor in

Molecular Genetics and

Nanobiotechnology, Centre of Innovation

in Personalised Medicine, King Fahad Medical

Research Centre, King Abdulaziz University, KSA.

Jan 2012- present Honorary Research Fellow in the College of Life Sciences

and Medicine, University of Aberdeen, UK.

May-Aug 2009 Co- supervisor for MSc candidate. University of Aberdeen,

UK. Project Title: Development of Biosensors for Carcinogenicity

and Mutagenicity detection.

May-Aug 2008 Co- supervisor for MSc candidate. University of Aberdeen, UK.

Project Title: Bioaccessibility of Carcinogenic Chemicals; Relating

Empirical Data to Human Health Risk Assessment Models.

2008-2011 Graduate Research Associate and Demonstrator, College of

Life Sciences and Medicine, University of Aberdeen, UK. The

work involved demonstrating in practical classes for

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undergraduate students and marking practical reports. Course

Title: The Cell.

2004-2006 Demonstrator, College of Applied Medical Sciences.

The work involved preparing practical sessions, demonstrating

and teaching in practical classes, conducting tutorial sessions,

setting-up practical exams, and marking practical reports and

exams. Course Title: Molecular Biology.

June-Aug 2005 Research Assistant, King Fahad Medical Research Center, King

Abdulaziz University, KSA. Project Title: Seroepidemiological

study of RVF virus among abattoir worker in Saudi Arabia.

April-July 2004 Medical Technologist, Diagnostic Virology including class-III

molecular Virology Unit, King Fahad Medical Research Centre,

King Abdulaziz University, KSA. I was involved in different

techniques such as applications of PCR, restriction enzyme

and gel electrophoresis, performing of different extraction

tests for DNA and RNA for viruses, isolation of different

viruses, CPE detection, inoculation of viruses into culture,

further investigation for detection of different types of viruses

such as: Haem-agglutination test, ELISA and Haem-adsorption

test. I was also involved in a research project entitled:

Detection of the most dominant strains of influenza virus in Saudi

populations in affiliation with WHO.

Jan-March 2004 Medical Technologist, Genomic Medicine Unit, King Fahad

Medical Research Centre, King Abdulaziz University, KSA. The

work involved cryptogenetic and chromosomal analysis

including: taking patient history, assessing the need for

chromosomal analysis, cell culture and harvesting, spreading

and staining chromosomes followed by automated and manual

karyotyping.

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July-Dec 2003 Medical Technologist, Diagnostic Immunohematology

Laboratory, King Khaled National Guard Hospital, KSA. The

job involved carrying out routine tests involved in Blood Bank

laboratory including: preparation of different blood

components, cryoprecipitate, in-house leuko-depletion, ABO/

Rh grouping, extended antigen typing, antibody screen, direct

anti-globulin testing, immediate-spin and antiglobulin-phase

cross matches and quality control studies.

Aug-Dec 2003 Research Assistant, King Khaled National Guard Hospital,

KSA. Project Title: The dominant and recessing antibody in sickle

cell anemia patient in Saudi populations.

Publications -Hani A. Alhadrami, Lenka Mbadugha and Graeme I. Paton (2016)

Hazard and risk assessment of human exposure to toxic metals using in vitro

digestion assay. Chemical Speciation & Bioavailability. Vol. 28, No. 1-4, 78-87. doi:

10.1080/09542299.2016.1180961

-Hani A. Alhadrami, Faten Al-Hazmi, Jun Yang and Fahrettien (2016).

Microwave Assisted Synthesis and characterization of TiO2 Nanoroads for

Antibacterial Applications (Submitted).

-Hani A. Alhadrami, Musab Aldhahri, M. Asif Hussain, Mohammed

Shaban, Ali Khademhosseini and Adnan Memic (2016). Nanocoating on

nanofibers for strain specific antibacterial activity (Submitted).

-Hani A. Alhadrami and Graeme I. Paton (2013) The Potential

Applications of SOS-lux Biosensors for Rapid Screening of Mutagenic

Chemicals. FEMS Microbiology Letters, 344 (2013) 69-76

-Hani A. Alhadrami and Graeme I. Paton (2013) Validation of SOS-lux Microbial

Biosensors for Mutagenicity Assessment: Mitomycin-C as a model compound.

Biosensors and Bioelectronics, 4:142 doi: 10.4172/2155-6210.1000142.

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-Hani A. Alhadrami, Ken S. Killham and Saad A. Alamri (2008). Assessing the

Potential of Flow Bioreactors to Minimise Impacts on Human Health. Biotechnology

7 (3): 448-455.

-Hani A. Alhadrami, Julian J.C Dawson, Graeme I. Paton and Ken Killham

(2008). Flow Bioreactors and Minimisation of Human Health Impacts. Paper

presented in Saudi International Innovation Conference, University of Leeds, UK,

09-10 June 2008. ISBN: 978-0-9559241-2-5.

-Adnan Memic, Hani A. Alhadrami, M. Asif Hussain, Musab Aldhahri,

Fozia Al Nowasiser, Faten Al-Hazmi, Rahim Oklu and Ali Khademhosseini

(2016). Hydorgels 2.0: Improved Properties with Nanomaterial Composites

for Biomedical Applications. Biomedical Materials. 11 (2016) 014104. doi:

10.1088/1748-6041/11/1/014104

-Ashraf Dallol, Abdelbaset Buhmeida, Mahmoud S. Al-Ahwal, Jaudah Al-

Maghrabi, Osama Bajouh, Shadi Al-Khayyat, Rania Alam, Atlal Abusanad, Rola

Turki, Aisha Elaimi, Hani A. Alhadrami, Mohammed Abuzenadah, Huda

Banni, Mohammed Al-Qahtani, Adel M. Abuzenadah (2016). Clinical

significance of frequent somatic mutations detected by high-throughput

targeted sequencing in archived colorectal cancer samples. Journal of

Translational Medicine. 4;14(1):118. doi: 10.1186/s12967-016-0878-9.

-Su Ryon Shin, Yu Shrike Zhang, Duck-Jin Kim, Ahmad Manbohi, Tugba Kilic,

Antonia Silvestri, Solange Massa, Julio Aleman, Hani A. Alhadrami, Reza

Rahi, Adel Pourmand, Mehmet R. Dokmeci, Ali Khademhosseini (2016).

Aptamer-based microfluidic electrochemical biosensor for monitoring cell-

secreted trace cardiac biomarkers. Analytical Chemistry (Accepted and in press).

-Usman Jamil Rajput, Hani A. Alhadrami, Faten Al-Hazmi, Jun Yang

(2016). Two-chamber Integrated Photocatalytic and Solar-thermal System

For Water Heating and Cleaning. Applied Energy (in press).

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-Gaston Contreras Jimenez, Shimaa Eissa, Andy Ng, Hani A. Alhadrami,

Mohammed Zourob, Mohamed Siaj (2015). Aptamer-Based Label-Free

Impedimetric Biosensors for the Detection of Progesterone. Analytical

Chemistry, (87), 1075-1082

-Anwarul Hasan, Amir Sanati-Nezhad, Mohammad Ariful Islam, John Saliba,

Hani A. Alhadrami, Adnan Memic, Ayad Jaffa (2015). Engineering Cell

Surface Interface in Tissue Engineering and Cell Based Biosensors. Chapter in:

Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and

Imaging Technologies. CRC press, ISBN 9781482256123 - CAT No. K24047.

November 18, 2015 Series: Devices, Circuits, and Systems.

-Hussain, M.A., Memic, A., Al-Othmani, N.S., Al-Dhahiri, R.W., Al-Hazmi, F.,

Hani A. Alhadrami, Ali Khademhosseini (2015). Characterisation of

Fibrous Scaffold Using Quantitative Nano-Mechanical Mapping Mode of

Atomic Force Microscope. International Journal of Basic and Applied Biology,

Volume 2, pp. 364-367.

-Aftab Ahmad, Asif Husain, Mohd Mujeeb, Shah Alam Khan, Hani A.

Alhadrami, Anil Bhandari (2015) Quantification of Total Phenol, Flavonoid

Content and Pharmacognostical Evaluation Including HPTLC Fingerprinting

for the Standardisation of Piper Nigrum Linn Fruits. Asian Pacific Journal of

Tropical Biomedicine, 2015; 5(2): 101-107.

-E.E. Diplock, H.A. Alhadrami, and G.I. Paton (2010) Application of Microbial

Bioreporters in Microbiology and Bioremediation. Chapter on Whole Cell Sensing

System II, Series: Advances in Biochemical Engineering Biotechnology, Vol. 118, ISBN:

978-3-642-12852-3. Springer Berlin Heidelberg.

-E.E. Diplock, H.A. Alhadrami, and G.I. Paton (2009) Commercial Application of

Bioluminescence Full Cell Bioreporters. Chapter on Handbook of Hydrocarbon and

Lipid Microbiology, pages 4445-4458, part 36. ISBN 978-3-540-77584-3. Springer Berlin

Heidelberg.

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Research Skills Lab-on-a chip and microfluidics technology.

Tissue Engineering and fabrication of electrochemical sensors.

Fabrication of DNA-Aptamer based biosensors.

Characterisation and optimisation of Ames assay (Salmonella Mutagenicity Assay)

for mutagenicity and carcinogenicity assessment of medical samples.

Use and operation of different analytical chemistry instruments such as flame

atomic absorption spectrophotometer, HPLC and UV/Vis spectrophotometer.

Characterisation, development and optimisation of several bioluminescence SOS-

lux based microbial biosensors for mutagenicity and carcinogenicity assessment

of human health risk assessment.

Development and optimisation of in vitro gastrointestinal bioassay for organic and

inorganic carcinogens to simulate the different oral exposure scenarios for

children, based on human physiology.

Good experience in tissue culture, isolation of different viruses, CPE detection,

inoculation of viruses into culture, further investigation for detection of different

types of viruses such as: Haem-agglutination test, Haem-agglutination inhibition,

IFT, ELISA, and Haem-adsorption test.

Sufficient experience in the use and the operation of Polymerase Chain

Reaction (PCR), Gene Cloning, Restriction Enzyme, DNA and RNA extractions

and Gel Electrophoresis by using both polyacralmyied and Agarose gel.

Awards Awarded the Prize for the Best Oral Presentation in the annual conference of

the Society for Applied Microbiology, Brighton, UK, 2010.

Awarded Honorary Certificate from the Vice-Principal of King Faisal University

for the Excellent academic performance during the course of my PhD studies,

2010.

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Awarded Honorary Certificate and a Prize for the Excellent academic

performance during the third year of my PhD, Saudi Cultural Bureau in London,

UK, 2010.


performance during the second year of my PhD, Saudi Cultural Bureau in

London, UK, 2009.


performance during the first year of my PhD, Saudi Cultural Bureau in London,

UK, 2008.


performance during my Master degree, Saudi Cultural Bureau in London, UK,

2007.


performance during my BSc (Honour) degree, King Abdulaziz University,

Jeddah KSA, 2004.

Computing Skills • Ability to work with scientific research databases such as Scopus, Web of

Knowledge, ScienceDirect and PubMed.

• Use of statistical software such as Sigma Plot and Minitab, Microsoft Office

(Word, Excel, Power Point), and iWork (Pages, Numbers and Keynote).

Memberships Society for General Microbiology (2008-present).

Society for Applied Microbiology (2008-present).

American Society for Microbiology (2010-present).

Institute of Nanotechnology (2010-present).

Reviewer in the Journal of Biosensors and Bioelectronics, Elsevier.

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Conferences August 2016 The Global Biotechnology and Drug Delivery

Congress, Boston, MA, United Sates of America. Oral Presentation: Nanocoating on Nanofibers for Strain Specific Antibacterial Activity.

Dec 2015 Third International Genomic Medicine Conference: King Abdulaziz University, Jeddah, KSA. Poster Presentation: Simultaneous genetic screening of the coagulation pathway genes using the Thromboscan targeted sequencing panel.

July 2014 Workshop on: Micro and Nanotechnologies for Medicine: Emerging Frontiers and Applications. Harvard Medical School and Harvard-MIT Health Science and Technology, Cambridge, MA (USA).

June 2014 Biotech and Nanotech Conference and Expo 2014, Washington, DC. Poster Presentation: Microbial Biosensors for screening of mutagenic chemicals.

May 2013 Biotech and Nanotech Conference and Expo 2013, Washington, DC. Poster Presentation: The potential applications of SOS-lux biosensors for rapid screening of mutagenic chemicals.

May 2012 Biosensors World Congress 2012, Cancun, Mexico. Poster Presentation: Microbial Biosensors for Mutagenicity Assessment: Development, Applications and Verification.

July 2010 Society for Applied Microbiology Summer Conference, Brighton, UK. Oral presentation: Bioaccessibility of Carcinogens: Use of Microbial Biosensors for Human Health Hazard Assessment.

Awarded the Prize for the Best Oral Presentation.

May 2010 20th Anniversary World Congress on Biosensors, Glasgow, UK.

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April 2010 Society for General Microbiology Winter Meeting Edinburgh International Conference Centre, UK. Poster Presentation: Bioaccessibility of Mutagens: Assessment of Microbial Biosensors for Human Health Risk Assessment and Validation.

June 2008 Saudi International Innovation Conference,

University of Leeds, UK. Oral Presentation: Flow Bioreactors and Minimisation of Human Health Impacts.

April 2008 Knowledge Transfer Scotland: Policy and Practice, University of St Andrews, UK.

December 2002 The international conference and exhibition on molecular Applications, Jeddah, Saudi Arabia.

Social Activities

President of Saudi Society, University of Aberdeen, UK (Academic year

2009-2010).

President of Saudi Students Club, Aberdeen, UK (2008-2009).

Referees 1. Dr. Essam H. Jiffri. Associated Professor in Clinical Chemistry,

Head of Medical Laboratory Technology Department, Faculty of Applied Medical Sciences, King Abduaziz University, Jeddah, P. O. Box 80324, Jeddah 21589 Kingdom of Saudi Arabia. Tel: +966(0)505613915. Email: [email protected]

2. Prof. Mohammed Zourob, Professor in Bio-Medicine/Bio-Engineering, Translational Medicine, Department of Chemistry, Alfaisal University, Al Zahrawi Street, Al Maather, Al Takhassusi Rd, Riyadh 11533, Saudi Arabia. Tel: +966(0)555017547 Email: [email protected]

3. Prof. Ali Khademhosseini. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Whys Institute for Biologically Inspired Engineering, Harvard Medical School, Harvard University, Boston, MA 02115, USA. Office: (617)768-8395, Mobile: (617)388-9271. Email: [email protected]

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Dr. Hani's Alhadrami CV - MEMBS. Hani's Alhadra… · -Anwarul Hasan, Amir Sanati-Nezhad, ... Hani A. Alhadrami, Ali Khademhosseini ... and Gel Electrophoresis by using both polyacralmyied