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DISLIPIDEMIAS
Funciones de los lípidos
• Función de reserva. • Función estructural. • Función biocatalizadora. • Función transportadora.
Estructura de la membrana celular
CLASIFICACIÓN Y COMPOSICIÓN DE LAS LIPOPROTEÍNAS
Estructura de VLDL
Las vias metabólicas exógenas y endógenas de las lipoproteínas
Metabolismo de las HDL y transporte inverso de colesterol
fenotipo 1 IIa II b III IV V
Lipoproteína
Quilo-micrones
LDL LDL y VLDL
Restos de quilomicrones y VLDL
VLD quilomicrones y VLDL
Triglicéridos ++++ -- ++ ++ a +++ ++ ++++
Colesterol + a++ +++ ++ a +++ ++a+++ --a + ++ a +++
C-LDL ↓ ↑ ↑ ↓ ↓ ↓↓
C- HDL +++ + ++ ++ ++ +++
Aspecto del plasma
Lechoso Claro Claro Turbio Turbio Lechoso
Xantomas Eruptivos Tendones, tuberoso
Ninguna Palmares, tuberoeruptivos
Ninguna Eruptivo
Pancreatitis +++ 0 0 0 0 +++
Aterosclerosis coronaria
0 +++ +++ +++ +/- + / -
Aterosclerosis periférica
0 + ++ + + + / - + / -
Nomenclatura genética
FCS FH, FDB, ADH, ARH,
FCHL FDBL FHTG FHTG
Criterios Med-Ped de Hipocolesterolemia Familiar
Criterios diagnósticos de Hiperlipemia Familiar Combinada
GUIAS CLÍNICAS DE LA SOCIEDAD GALLEGA DE MEDICINA INTERNA
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
(Zocor)
(Mevacor)(Pravacol)
(Lescol)(Lipitor)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
( LOPID )( CONTROLIP ) ( HIPERLIPEN )
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)