Diet for Chronic Renal Failure

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    Diet for Chronic Renal Failure

    Ezekiel T. Arteta

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    Kidney Function

    Detoxify blood

    Increase calcium absorption

    Calcitriol

    Stimulate RBC production

    Erythropoietin

    Regulate blood pressure and electrolyte

    balance Renin

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    Determinants of GFR

    Other factors:

    Rate of Plasma flow

    Total Surface area of the glomerular capillaries

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    Chronic Renal Failure

    150200 cases per million people = new cases

    each year

    Chronic renal failure and ESRD affect morethan 2 out of 1,000 people in the U.S

    Mortality = 20%

    Progressive, irreversible damage to

    the nephrons and glomeruli

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    Acute Versus Chronic

    Acute

    sudden onset

    rapid reduction in urine output

    Usually reversible

    Tubular cell death and regeneration

    Chronic

    Progressive

    Not reversible

    Nephron loss

    75% of function can be lost before its noticeable

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    Stages of CRF

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    Chronic Renal Failure Causes

    Diabetic Nephropathy

    Hypertension

    Glomerulonephritis

    HIV nephropathy

    Reflux nephropathy in children

    Polycystic kidney disease Kidney infections & obstructions

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    CRF Symptoms

    Malaise

    Weakness

    Fatigue

    Neuropathy

    CHF

    Anorexia

    Nausea

    Vomiting

    Seizure

    Constipation

    Peptic ulceration

    Diverticulosis

    Anemia

    Pruritus

    Jaundice Abnormal hemostasis

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    CRF Effects

    Decreased: GFR, tubular function & tubularreabsorption capabilities.

    Dysfunction of fluids & electrolytes,

    Acid base disturbances, &

    Systemic problems

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    Protein Restriction

    Protein = Malnutrition; Protein = urea

    Protein Diet

    Protein Metabolism

    Product: AMMONIA

    Urea Cycle Product: UREA

    GFR Urea accumulates in the blood SUN

    Uremia

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    Protein Restriction

    Other effects of High Protein diet

    Severe acidosis (serum bicarbonate 7mg/dl)

    severe azotaemia (blood urea nitrogen values

    >120mg/dl)

    Hyperuricaemia

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    Protein Restriction

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    Protein Restriction

    BEFORE DIALYSIS: Low-protein diet

    AFTER DIALYSIS: Increased-Protein diet

    compared to the diet before dialysis. Recommended amount: 2 grams/kg weight

    Good quality Proteins

    eggs, milk, meat, fish and poultry.

    Proteins of lower biological value

    pulses, cereals, nuts, oilseeds and in some

    vegetables like greenpeas and dried beans.

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    Treatment Modalities

    Decrease fluid 1000ml/day

    Decrease protein (.5-1kg body weight)

    Decrease sodium (1-4gm variable)

    Decrease potassium

    Decrease phosphorous (

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    Fluid and Sodium Control

    Impaired renal mechanisms for conservingsodium and water.

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    Fluid and Sodium Control

    GFR

    Aldosterone

    Na+

    and water reabsorption

    Intravascular fluid

    Edema Hypertension

    Further damageCadiovascular and

    Respiratory effects

    Renin,angiotensin

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    Fluid and Sodium Control

    Rise in body weight and Pressure

    Retention of sodium and fluid

    Decline in body weight and Pressure

    Fluid loss

    Water intake must not exceed the capacity for

    free water clearance

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    FOODSTUFFS HIGH IN SODIUM

    Baking soda

    Salt

    Ajinomoto

    Salted wafers, popcorns, salted biscuits.Papads all varieties.

    Salted pickles, chutneys, curry powder commercial.

    Commercial salad dressings and sauces.

    Soup cubes.

    Soft drinks containing sodium benzoate.

    Bakery products, bread , biscuits.

    Nuts such as salted cashewnuts, pistachio, walnuts, peanuts.

    Commercial cheese.

    Preservative containing foods.

    Canned and tinned foods.

    Sea food, chicken, dry fish, bacon, ham .

    Meat and yeast extracts like marmite.

    Proprietary drinks Bournvita , chocolate drinks , Horlicks.

    Milk and curds.

    Pulses and legumes all varieties.

    Vegetables such as cauliflower , snakegourd , beetroot , carrot , coriander leaves,fenugreek(methi) leaves, lettuce ,spinach(palak) ,amaranth, radish

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    Rich in Sodium

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    Rich in Fluid

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    Treatment Modalities

    Decrease fluid 1000ml/day

    Decrease protein (.5-1kg body weight)

    Decrease sodium (1-4gm variable)

    Decrease potassium

    Decrease phosphorous (

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    Potassium Control

    GFR renal K+ excretion GI K+

    excretion

    Certain drugs inhibitK+

    entry into cells orK+

    secretion in the distal nephron.

    Beta blockers,ACE inhibitors and angiotensin

    receptor blockers, K-sparing diuretics (amiloride,

    triamterene, spironolactone), and NSAIDs

    HYPERKALEMIA

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    Potassium Control

    Leaching

    Method 1: Wash, peel and cut vegetables into

    small pieces. Soak in warm water for 2-3 hours.

    Discard water. Add large volume of fresh water

    and cook vegetables. Discard water.

    Method 2:Peel vegetables and cut into small

    pieces. Bring to a boil in a large quantity of water.Discard water and cook in a large volume of fresh

    water. Discard excess water.

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    Treatment Modalities

    Decrease fluid 1000ml/day

    Decrease protein (.5-1kg body weight)

    Decrease sodium (1-4gm variable)

    Decrease potassium

    Decrease phosphorous (

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    Phosphorus, Vitamin D and Calcium

    Phosphorus and calcium

    Slows down renal failure and prevent bone disease

    renal function active Vit. D

    phosphorus in the body

    renal function active Vit. D calciumin the body

    phosphorus + calcium = BONE RESORPTION

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    Phosphorus, Vitamin D and Calcium

    List Of Foods High In Phosphorus

    All-bran Cereal

    Almonds

    Beef

    Brazil Nuts

    Cashew Nuts

    Cheese

    Chicken

    Dried Fruit

    Egg Garlic

    Halibut Fish

    Hard Potatoes

    Legumes

    Lentils

    Liver

    Meat

    Milk

    Peanuts

    Poultry

    Roe

    Salmon

    Sesame Seeds

    Sunflower Seeds

    Turkey Wheat Bran

    Wheat Germ

    Whole Wheat

    Bread Yogurt

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    Phosphorus, Vitamin D and Calcium

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    Phosphorus, Vitamin D and Calcium

    BALANCED INTAKE OF CALCIUM AND VIT. D

    Too much calcium: HYPERCALCEMIA

    Too much Vitamin D: VITAMIN D TOXICITY

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    Caloric Intake

    Patients with CHF needs enough energy

    Prevent protein catabolism and to maintain a

    desirable weight.

    As renal failure progresses, consuming

    adequate energy becomes difficult.

    Energy needs are slightly lower once dialysis

    begins.

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    Other Considerations

    Thiamin (B1)

    Folate

    Vitamin B6

    Vitamin B12

    Water-soluble vitamins

    Fat-soluble vitamins

    Iron

    Erythropoietin

    Zinc

    AVOID

    Aluminum

    Magnesium