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School of Cybernetics, School of Systems Engineering, University of Reading Presentation Skills Workshop March 22, ‘11 Diagnosis of Breast Diagnosis of Breast Cancer by Modular Cancer by Modular Evolutionary Neural Evolutionary Neural Networks Networks Rahul Kala, School of Cybernetics, School of Systems Engineering University of Reading http://rkala.99k.org/ [email protected], [email protected] Publication of paper: R. Kala, R. R. Janghel, R. Tiwari, A. Shukla (2011) Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks, International Journal of Biomedical Engineering and Technology, 7(2): 194 – 211.

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Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks. Rahul Kala, School of Cybernetics, School of Systems Engineering University of Reading http://rkala.99k.org/ [email protected], [email protected]. - PowerPoint PPT Presentation

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Page 1: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Diagnosis of Breast Diagnosis of Breast Cancer by Modular Cancer by Modular Evolutionary Neural Evolutionary Neural NetworksNetworks

Rahul Kala,

School of Cybernetics, School of Systems Engineering

University of Reading

http://rkala.99k.org/

[email protected], [email protected] of paper: R. Kala, R. R. Janghel, R. Tiwari, A. Shukla (2011) Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks, International Journal of Biomedical Engineering and Technology, 7(2): 194 – 211. 

Page 2: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Presentation to the paperPresentation to the paper

R. Kala et al. (2011) Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks, International Journal of Biomedical Engineering and Technology [Accepted, In Press]

Research Sponsored by:

Indian Institute of Information Technology and Management Gwalior, INDIA

Page 3: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Biomedical EngineeringBiomedical Engineering

Page 4: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

The ProblemThe Problem

Page 5: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Data SetData Set

Data Set Available At: W. H. Wolberg, O. L. Mangasarian, D. W. Aha. UCI Machine Learning Repository [http://www.ics.uci.edu/~mlearn/MLRepository.html], University of Wisconsin Hospitals, 1992.

Page 6: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Machine Learning Machine Learning PerspectivePerspective

Data Set

Page 7: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Not in agendaNot in agenda

Page 8: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Concept – 1: Evolutionary Concept – 1: Evolutionary Neural NetworkNeural Network

Generate random individuals

While Stopping Criterion not met

Selection

Fitness Evaluation

Return best individual

Yes

No

Create Neural Network as per individual specifications

Training Algorithm as local search strategy

Performance/Connection Penalty Evaluation

Crossover

Mutation

Elite

Sys

tem

2

System 1

Page 9: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Concept – 2: Attribute Concept – 2: Attribute DivisionDivision

Attribute Division

Inputs

Attribute Set 1

Attribute Set 2

Evolutionary Neural Net 1

Evolutionary Neural Net 2

Result Integration Output

Page 10: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Concept – 3: Input Space Concept – 3: Input Space DivisionDivision

Input Space Clustering

Inputs

Cluster 1

Cluster 2

Attribute Division 1

Attribute Division 2

Result Integration Output

Cluster 3 Attribute Division 3

Page 11: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Concept – 3: Input Space Concept – 3: Input Space DivisionDivision

Input Space Clustering

Inputs

Attribute Set 1

Attribute Set 2

Evolutionary Neural Net 1

Evolutionary Neural Net 2

Result Integration

Output

Cluster 1 Cluster 2 Cluster 3

Attribute Set 1

Attribute Set 2

Attribute Set 1

Attribute Set 2

Evolutionary Neural Net 2

Evolutionary Neural Net 2

Evolutionary Neural Net 2

Evolutionary Neural Net 2

Result Integration

Result Integration

Cluster Result Integration

Page 12: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Concept 4: Mixture of Concept 4: Mixture of ExpertsExperts

Same input to all Experts

InputsInputs

Expert 1: Multi Layer Perceptron-1

Result Integration

OutputOutput

Expert 3: Multi Layer Perceptron-2

Expert 2: Radial Basis Function

Network

Page 13: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

ResultsResultsS. No. Method Training

AccuracyTesting Accuracy

1. Proposed Algorithm 98.5075% 95.8084%

2. Modular Neural Network

94.4020% 91.4773%

3. Ensembles 98.2188% 94.8864%

4. Evolutionary Neural Network

96.2779% 95.7831%

Page 14: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Component ResultsComponent ResultsCode Expert Number Cluster Number Module

NumberTraining Accuracy

Testing Accuracy

A Entire System (all experts combined) 98.5075% 95.8084%E1 Expert 1: Multi-Layer Perceptron (all clusters combined) 98.0100% 95.8084%E1.C1 Multi-Layer Perceptron-1 1 (all modules combined) 98.9362% 98.4848%E1.C1.M1 Multi-Layer Perceptron-1 1 1 98.9362% 95.4545%E1.C1.M2 Multi-Layer Perceptron-1 1 2 99.4681% 98.4848%E1.C2 Multi-Layer Perceptron-1 2 (all modules combined) 97.5000% 92.0635%E1.C2.M1 Multi-Layer Perceptron-1 2 1 93.3333% 84.1270%E1.C2.M2 Multi-Layer Perceptron-1 2 2 97.5000% 93.6508%E1.C3 Multi-Layer Perceptron-1 3 (all modules combined) 96.8085% 97.3684%E1.C1.M1 Multi-Layer Perceptron-1 3 1 96.8085% 97.3684%E1.C1.M2 Multi-Layer Perceptron-1 3 2 100% 96.8085% E2 Expert 2: Radial Basis Function Network 98.0100% 95.8084%E2.C1 Radial Basis Function 1 (all modules combined) 98.9362% 98.4848%E2.C1.M1 Radial Basis Function 1 1 97.8723% 93.9394%E2.C1.M2 Radial Basis Function 1 2 99.4681% 96.9697%E2.C2 Radial Basis Function 2 (all modules combined) 96.6667% 93.6508%E2.C2.M1 Radial Basis Function 2 1 94.1667% 88.8889%E2.C2.M2 Radial Basis Function 2 2 96.6667% 88.8889%E2.C3 Radial Basis Function 3 (all modules combined) 100% 97.3684%E2.C1.M1 Radial Basis Function 3 1 98.9362 97.3684%E2.C1.M2 Radial Basis Function 3 2 100% 97.3684%E3 Expert 1: Multi-Layer Perceptron (all clusters combined) 98.7562% 95.8084%E3.C1 Multi-Layer Perceptron-2 1 (all modules combined) 98.9362% 98.4848%E3.C1.M1 Multi-Layer Perceptron-2 1 1 98.9362% 95.4545%E3.C1.M2 Multi-Layer Perceptron-2 1 2 98.9362% 98.4848%E3.C2 Multi-Layer Perceptron-2 2 (all modules combined) 98.3333% 90.4762%E3.C2.M1 Multi-Layer Perceptron-2 2 1 95.0000% 85.7143%E3.C2.M2 Multi-Layer Perceptron-2 2 2 99.1667% 87.3016%E3.C3 Multi-Layer Perceptron-2 3 (all modules combined) 98.9362% 94.7368%E3.C1.M1 Multi-Layer Perceptron-2 3 1 100.0000% 97.3684%E3.C1.M2 Multi-Layer Perceptron-2 3 2 98.9362% 97.3684%

Page 15: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Related Publications - Related Publications - JournalsJournals Kala, Rahul, Tiwari, Ritu, & Shukla, Anupam (2011) Breast Cancer

Diagnosis using Optimized Attribute Division in Modular Neural Networks, Journal of Information Technology Research, Vol. 4, No 1, pp 34-47

Kala, Rahul, Janghel, Rekh Ram, Tiwari, Ritu, & Shukla, Anupam, (2011) Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks, International Journal of Biomedical Engineering and Technology, Inderscience [In Press]

Kala, Rahul, Vazirani, Harsh, Khawalkar, Nishant, & Bhattacharya, Mahua (2010) Evolutionary Radial Basis Function Network for Classificatory Problems, International Journal of Computer Science Applications, TMRF India, Vol. 7, No. 4, pp 34-49

Kala, Rahul, Vazirani, Harsh, Shukla, Anupam, & Tiwari, Ritu (2010) Medical Diagnosis using Incremental Evolution of Neural Network, Journal of Hybrid Computing Research, TMRF India , Vol. 3, No. 1, pp 9-17

Kala, Rahul, Vazirani, Harsh, Shukla, Anupam, & Tiwari, Ritu (2010) Evolution of Modular Neural Network in Medical Diagnosis, International Journal of Applied Artificial Intelligence in Engineering System, Vol. 2, No. 1, pp 49 -58

Page 16: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Related Publications - Related Publications - ConferencesConferences Meena, Yogesh Kumar, Arya, Karam Veer, Kala, Rahul (2010) Classification using

Redundant Mapping in Modular Neural Networks, Proceedings of the 2010 World Congress on Nature and Biologically Inspired Computing, Kitakyushu, Japan [In Press]

Janghel, R. R., Shukla, Anupam, Tiwari, Ritu, Kala, Rahul (2010) Breast Cancer Diagnostic System using Symbiotic Adaptive Neuro-evolution (SANE). Proceedings of the 2010 International Conference of Soft Computing and Pattern Recognition, Cercy Pontoise/Paris, France, pp 326-329.

Janghel, R. R., Shukla, Anupam, Tiwari, Ritu, Kala, Rahul (2010) Breast Cancer Diagnosis using Artificial Neural Network Models. Proceedings of the IEEE 3rd International Conference on Information Sciences and Interaction Sciences, pp 89-94, Chengdu, China.

Vazirani, Harsh, Kala, Rahul, Shukla, Anupam, Tiwari, Ritu (2010) Diagnosis of Breast Cancer by Modular Neural Network. Proceedings of the Third IEEE International Conference on Computer Science and Information Technology, pp 115-119, Chengdu, China

Kala, Rahul, Shukla, Anupam, & Tiwari, Ritu (2009) Comparative analysis of intelligent hybrid systems for detection of PIMA indian diabetes, Proceedings of the IEEE 2009 World Congress on Nature & Biologically Inspired Computing, NABIC '09, pp 947 - 952, Coimbatote, India

Kala, Rahul, Shukla, Anupam, Tiwari, Ritu (2009) Fuzzy Neuro Systems for Machine Learning for Large Data Sets, Proceedings of the IEEE International Advance Computing Conference, IACC '09, pp 541-545, Patiala, India

Page 17: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

More from the authorsMore from the authors

Page 18: Diagnosis of Breast Cancer by Modular Evolutionary Neural Networks

School of Cybernetics, School of Systems Engineering,

University of ReadingPresentation Skills WorkshopMarch 22, ‘11

Thank You Thank You Rahul Kala

Call Centre Lab, Room No 188,

School of Cybernetics,

School of Systems Engineering,

University of Reading, Whiteknights

http://rkala.99k.org/

[email protected]

[email protected]

Ph: +44 (0) 7424752843

Acknowledgements

Prof. Anupam Shukla,

Professor, IIITM Gwalior

Dr. Ritu Tiwari,

Assistant Professor, IIITM Gwalior

Mr. R. R. Janghel,

Research Scholar, IIITM Gwalior