Detection and visualization of conserved cis · 2012-05-02 · NesPlacZ/3 and E/nestin:EGFP mice showed reporter gene expression in stem cell-containing regions of brain and spinal

Feb-8-05 Biomedical Informatics - CCHMC 1

Detection and visualization of conserved cis-element structures and their annotation using NLP-based extraction and GFF-formatting of biomedical

literature-derived SO features

Anil Jegga & Jing ChenBiomedical Informatics

Cincinnati Children’s Hospital Research Foundation


Objectives• Extracting sequence regulatory features from

GenBank and MedLine• Representation of the known regulatory regions

in the context of computationally identifiedputative regulatory regions (GenomeTrafac).

• Export of GenomeTrafac tracks in GFF - Displayin UCSC genome browser.


Regulatory Region

→Attenuator

→Enhancer

→PolyA signal

→Promoter

→Silencer

→Splice enhancer

→Terminator

→TF binding site

A sequence segment located between the promoter and a structural gene that causespartial termination of transcription.

A cis-acting sequence that increases the utilization of (some) eukaryotic promoters,and can function in either orientation and in any location (upstream or downstream)relative to the promoter. (Enhancer: ≥1 TFBS?) (Intragenic OR Intergenic)The recognition sequence necessary for endonuclease cleavage of an RNA transcriptthat is followed by polyadenylation; consensus=AATAAA.

The region on a DNA molecule involved in RNA polymerase binding to initiatetranscription.

Combination of short DNA sequence elements which suppress the transcription of anadjacent gene or genes. (Silencer = One or more TFBS?)

Region of a transcript that regulates splicing.

The sequence of DNA located either at the end of the transcript that causes RNApolymerase to terminate transcription.

A region of a molecule that binds to a transcription factor.

A DNA sequence that controls the expression of a gene.

Located Sequence FeaturesSequence Ontology

GeneRegion

http://song.sourceforge.net/so.shtml


Missing Terms in SOFA?MeSH Definitions

• Locus Control Region: “A regulatory region firstidentified in the human beta-globin locus butsubsequently found in other loci. The region is believedto regulate TRANSCRIPTION by opening andremodeling CHROMATIN structure. It may also haveENHANCER activity”.

• Insulator: “Nucleic acid regulatory sequences that limitor oppose the action of ENHANCER ELEMENTS anddefine the boundary between differentially regulatedgene loci”.

• Operator: “The regulatory elements of an OPERON towhich activators or repressors bind thereby effecting thetranscription of GENES in the operon”.


Enhancer: 64636 entries (GenBank Nucleotide Sequences)!

Enhancer [Limited to “Feature Key”]: 1045LOCUS AF187727 315 bp DNA linear PRI 23-AUG-2000DEFINITION Homo sapiens APOB intestinal enhancer, complete sequence.ACCESSION AF187727VERSION AF187727.1 GI:9885269KEYWORDS .SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.REFERENCE 1 (bases 1 to 315) AUTHORS Antes,T.J., Goodart,S.A., Huynh,C., Sullivan,M., Young,S.G. and Levy-Wilson,B. TITLE Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine JOURNAL J. Biol. Chem. 275 (34), 26637-26648 (2000) MEDLINE 20409023 PUBMED 10859308FEATURES Location/Qualifiers source 1..315 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" /chromosome="2" enhancer 1..315 /note="APOB intestinal enhancer"ORIGIN 1 aattcaattc tcctgccctt gctacctcta tggattagag agagggagat agacatgcac

GenBank Search


Regulatory Region

→Attenuator

→Enhancer

→PolyA signal

→Promoter

→Silencer

→Splice enhancer

→Terminator

→TF binding site

Located Sequence FeaturesSequence Ontology

GeneRegion

4107161930

00

0677

0629

11334400552

5443018187

104564636

108327

With Feature keyWithout Feature key

GenBank Search


29816349splice enhancer

554646intronic splice enhancer

13137575exonic splice enhancer

27227210921092enhancer by bound factor

42542511531153silencer

674473872151923861enhancer

quoted +Genes

plain +GenesquotedplainTerm

E.g. Enhancer AND “Genes”[MeSH];“Enhancer” AND “Genes”[MeSH] MedLine Search


2163: Brickner AG, Gossage DL, Dusing MR, Wiginton DA.

Identification of a murine homolog of the human adenosine deaminase thymic enhancer.Gene.1995 Dec 29;167(1-2):261-6.

1: U72392 Mus musculus adenosine deaminase (Ada) gene, thymicenhancer region, partial first introngi|1613865|gb|U72392.1|MMU72392[1613865]

2: NM_007398 Mus musculus adenosine deaminase (Ada), mRNAgi|31982514|ref|NM_007398.2|[31982514]

No. of nucleotide sequences related to first 500 abstracts: 5776

(= a total of ~46208 sequences)!

Enhancer: 21519 Abstracts

Enhancer [MeSH]: 10429

"Enhancer Elements (Genetics)"[MeSH]: 10429

"Genes"[MeSH] AND "Enhancer Elements (Genetics)"[MeSH]: 4042

MedLine Search


1: J Orthop Res. 2004 Jul;22(4):751-8.A silencer element in the cartilage oligomeric matrix protein gene regulates chondrocyte-

specific expression.Issack PS, Liu CJ, Prazak L, Di Cesare PE. Department of Orthopaedic Surgery,

Musculoskeletal Research Center, Hospital for Joint Diseases, NYU, 301 East 17thStreet, New York, NY, USA.

The molecular mechanisms by which mesenchymal cells differentiate into chondrocytes arepoorly understood. The cartilage oligomeric matrix protein gene (COMP) encodes anoncollagenous extracellular matrix protein whose expression pattern correlates withchondrocyte differentiation and arthritis. We have used the COMP promoter as a modelto identify regulatory sequences necessary for chondrocyte-specific expression and toidentify cell type-specific proteins that bind these sequences. We have previouslycloned 1.9 kilobases of the 5(') flanking promoter sequence of the murine COMP geneand by deletion analysis have identified two spatially distant chondrocyte-specificregulatory regions. One element is situated proximally (-125 to -75), and a secondregion is located distally (-1925 to -592) relative to the transcription start site. In thepresent study, we performed a finer deletion analysis of the region of the COMPpromoter from -1925 to -592 and identified a silencer region situated between -1775and -1725. This silencer binds sequence-specific protein complexes; the intensity ofthese complexes is greater in two different fibroblast cell lines (NIH3T3 and 10T1/2)than in chondrocytic RCS cells. Competition experiments localized the binding siteof these protein complexes from -1775 to -1746; deletion of this 30-bp site results ina selective increase in COMP promoter activity in fibroblasts. Four tandem repeatsof this 30-bp site are sufficient to confer negative transcriptional regulation on aheterologous promoter (SV40) in NIH3T3 fibroblasts. These results suggest thatnegative regulation of transcription is an important mechanism for chondrocyte-specificexpression of the COMP gene. PMID: 15183430 [PubMed - indexed for MEDLINE]


J Neurosci Res. 2002 Sep 15;69(6):784-94.Nestin enhancer requirements for expression in normal and injured adult CNS. Johansson

CB, Lothian C, Molin M, Okano H, Lendahl U. Department of Cell and MolecularBiology, Medical Nobel Institute, Karolinska Institute, Stockholm, Sweden.

The nestin gene is expressed in many CNS stem/progenitor cells, both in the embryo andthe adult, and nestin is used commonly as a marker for these cells. In this report weanalyze nestin enhancer requirements in the adult CNS, using transgenic mice carryingreporter genes linked to three different nestin enhancer constructs: the genomic ratnestin gene and 5 kb of upstream nestin sequence (NesPlacZ/3), 636 bp of the ratnestin second intron (E/nestin:EGFP), and a corresponding 714 bp region from thehuman second intron (Nes714tk/lacZ). NesPlacZ/3 and E/nestin:EGFP mice showedreporter gene expression in stem cell-containing regions of brain and spinal cord duringnormal conditions. NesPlacZ/3 and E/nestin:EGFP mice showed increased expression inspinal cord after injury and NesPlacZ/3 mice displayed elevated expression in theperiventricular area of the brain after injury, which was not the case for theE/nestin:EGFP mice. In contrast, no expression in adult CNS in vivo was seen in theNes714tk/lacZ mice carrying the human enhancer, neither during normal conditions norafter injury. The Nes714 tk/lacZ mice, however, expressed the reporter gene in reactiveastrocytes and CNS stem cells cultured ex vivo. Collectively, this suggests a speciesdifference for the nestin enhancer function in adult CNS and that elements outsidethe second intron enhancer are required for the full injury response in vivo.Copyright 2002 Wiley-Liss, Inc. PMID: 12205672 [PubMed - indexed for MEDLINE]

Identify relevant keywords


• Gene

• Exon

• Intron

• Repeat Elements

• TFBS (Hs, Mm,Conserved)

• Hs-Mm Alignment

• Regulatory:

• Promoter

• Enhancer

• Silencer

• Non-coding SNPsSequence Ontology: GenomeTrafac


LOCUS HSU57613 10975 bp DNA linear PRI 10-OCT-2001

DEFINITION Human interleukin-2 receptor alpha chain (IL2RA) gene, promoter

region and exon 1.

ACCESSION U57613 AF243502

FEATURES Location/Qualifiers

source 1..10975

/organism="Homo sapiens"

/mol_type="genomic DNA"

/db_xref="taxon:9606"

/chromosome="10"

/map="10p15-14"

gene 324..>10975

/gene="IL2RA"

enhancer 324..401

/gene="IL2RA"

/note="Positive regulatory region III.

enhancer 3828..3860

/gene="IL2RA"

/note="Positive regulatory region 1.

enhancer 3967..4040

/gene="IL2RA"

/note="Positive regulatory region II.Exon-7Splicing SNP

Exon-8nsSNP

Intron-7


enhancer:324..401 (GenomeTrafac: 36208-36285)

/note="Positive regulatory region III. A composite site with one consensus and one non-consensusgamma interferon activated sequence (GAS motif). Together these motifs mediate the bindingof Stat5A and Stat5B. An Ets binding site overlaps the consensus motif, whereas a GATAmotif overlaps the non-consensus GAS motif. PRRIII also contains an Ets binding sitedownstream of both GAS motifs; this Ets binding site can bind Elf-1. PRRIII is essentialfor IL-2 induced IL-2Ralpha promoter activity YT cells."

ConservedElements inHs-Mm


enhancer: 3967..4040 (GenomeTrafac: 39862-39882)

(GenomeTrafac 39904-39937)

/note="Positive regulatory region II, contains an essential binding site for Elf-1 and multiplesites for HMG-I(Y). The Elf-1 site is essential for PMA-induced IL-2Ralpha promoteractivity in Jurkat T cells and IL-2 induced IL-2Ralpha promoter activity in YT naturalkiller like cells."

AAAAAAAAAAAAAAAAAAA


enhancer: 3828..3860 (GenomeTrafac: 39723-39755)

/note="Positive regulatory region 1. This spans an NF-kB

site (GGGGAATCTCCC) and a CArG motif (CCTTTTATGG). An Sp1

site begins within PRRI and extends 3' of PRRI."

Conserved Element

AGGGGAATCTCCCTC

CCCTCTCCTTTTATG

Elementsspecific tohuman IL2RA


browser position chr10:6053512-6184278

browser pix 680

browser hide all

#browser dense ruler refGene ensGene tigrGeneIndex sanger22 uniGene genscan

# exon 1 data NM_000417

track name="Human Exons" description="Human IL2RA exons" color=0,128,128 visibility=2priority=1 useScore=0

chr10 GenomeTrafac exon 6093511 6094865 . - . NM_000417








# exon 2 data NM_008367

track name="Mouse Exons" description="Mouse Il2ra exons" color=128,0,128 visibility=2priority=2 useScore=0









# repeat 1 data NM_000417

track name="Human RepeatMask" description="Human Repeat Elements by RepeatMask" color=0,60,120visibility=2priority=3 useScore=1

chr10 GenomeTrafac repeat 6077386 6077435 87.66827762323152 . . DNA;DNA

































chr10 GenomeTrafac repeat 6183656 6183830 69.09600309953973 . .LINE;LINE

































































chr10 GenomeTrafac repeat 6126144 6126635 182.773097248537 . . LTR;LTR





























chr10 GenomeTrafac repeat 6171400 6171433 49.836912521265596 . .Low_complexity;Low_complexity













chr10 GenomeTrafac repeat 6137417 6137873 221.94684953407997 . .Other;Other

chr10 GenomeTrafac repeat 6181745 6182038 168.9643655878456 . .SINE;SINE








































































































chr10 GenomeTrafac repeat 6182535 6182562 52.26939481778517 . .Simple_repeat;Simple_repeat




























# local alignment NM_000417:NM_008367

track name="Local Alignments" description="Local Alignments Human vs. Mouse" color=0,0,255 visibility=1priority=4 useScore=0

chr10 GenomeTrafac similarity 6170430 6171380 . . .alignment;chr2:11735813-11736635




























chr10 GenomeTrafac similarity 6137242 6137383 . . .alignment;chr2:11690999-11691146chr10 GenomeTrafac similarity 6136968 6137199 . . .alignment;chr2:11690529-11690754chr10 GenomeTrafac similarity 6136642 6136832 . . .alignment;chr2:11690333-11690539chr10 GenomeTrafac similarity 6136086 6136463 . . .alignment;chr2:11689395-11689753chr10 GenomeTrafac similarity 6133853 6134960 . . .alignment;chr2:11686878-11688001chr10 GenomeTrafac similarity 6132765 6133504 . . .alignment;chr2:11685564-11686227chr10 GenomeTrafac similarity 6127131 6127780 . . .alignment;chr2:11683676-11684341chr10 GenomeTrafac similarity 6124052 6124295 . . .alignment;chr2:11683181-11683403chr10 GenomeTrafac similarity 6121740 6121971 . . .alignment;chr2:11677388-11677587chr10 GenomeTrafac similarity 6120139 6120669 . . .alignment;chr2:11676359-11676873chr10 GenomeTrafac similarity 6118382 6119574 . . .alignment;chr2:11674943-11675899chr10 GenomeTrafac similarity 6115848 6116693 . . .alignment;chr2:11673650-11674421chr10 GenomeTrafac similarity 6115306 6115860 . . .alignment;chr2:11672551-11673195chr10 GenomeTrafac similarity 6114667 6114903 . . .alignment;chr2:11668864-11669100chr10 GenomeTrafac similarity 6112781 6114330 . . .alignment;chr2:11667301-11668659chr10 GenomeTrafac similarity 6112218 6112770 . . .alignment;chr2:11666533-11667088chr10 GenomeTrafac similarity 6108622 6108796 . . .alignment;chr2:11665813-11665979chr10 GenomeTrafac similarity 6107638 6108119 . . .alignment;chr2:11664874-11665318chr10 GenomeTrafac similarity 6105606 6106468 . . .alignment;chr2:11662077-11662814chr10 GenomeTrafac similarity 6104776 6105269 . . .alignment;chr2:11661567-11662058chr10 GenomeTrafac similarity 6103859 6104781 . . .alignment;chr2:11659910-11660763chr10 GenomeTrafac similarity 6102814 6103856 . . .alignment;chr2:11658541-11659497chr10 GenomeTrafac similarity 6102349 6102494 . . .alignment;chr2:11658388-11658535chr10 GenomeTrafac similarity 6101806 6102231 . . .alignment;chr2:11657460-11657892chr10 GenomeTrafac similarity 6101329 6101536 . . .alignment;chr2:11656315-11656522chr10 GenomeTrafac similarity 6100015 6100609 . . .alignment;chr2:11655058-11655643chr10 GenomeTrafac similarity 6097028 6097079 . . .alignment;chr2:11653055-11653106chr10 GenomeTrafac similarity 6096268 6096344 . . .alignment;chr2:11651785-11651863chr10 GenomeTrafac similarity 6094413 6094943 . . .alignment;chr2:11649323-11649830chr10 GenomeTrafac similarity 6093859 6094368 . . .alignment;chr2:11648644-11649166chr10 GenomeTrafac similarity 6092879 6093362 . . .alignment;chr2:11647864-11648323chr10 GenomeTrafac similarity 6092552 6092838 . . .alignment;chr2:11647213-11647485chr10 GenomeTrafac similarity 6086767 6086806 . . .alignment;chr2:11645758-11645797chr10 GenomeTrafac similarity 6083203 6083339 . . .alignment;chr2:11645205-11645332chr10 GenomeTrafac similarity 6083204 6083323 . . .alignment;chr2:11645218-11645318chr10 GenomeTrafac similarity 6083100 6083238 . . .alignment;chr2:11645207-11645319chr10 GenomeTrafac similarity 6083015 6083141 . . .alignment;chr2:11645214-11645325chr10 GenomeTrafac similarity 6082928 6083047 . . .alignment;chr2:11645220-11645317chr10 GenomeTrafac similarity 6082840 6082952 . . .alignment;chr2:11645206-11645307chr10 GenomeTrafac similarity 6081586 6082590 . . .alignment;chr2:11643434-11644305chr10 GenomeTrafac similarity 6081058 6081414 . . .alignment;chr2:11643054-11643388chr10 GenomeTrafac similarity 6080429 6080490 . . .alignment;chr2:11643038-11643099chr10 GenomeTrafac similarity 6077284 6077384 . . .alignment;chr2:11638560-11638650chr10 GenomeTrafac similarity 6072688 6072815 . . .alignment;chr2:11638506-11638650chr10 GenomeTrafac similarity 6070860 6070982 . . .alignment;chr2:11636731-11636835chr10 GenomeTrafac similarity 6066626 6066804 . . .alignment;chr2:11636316-11636474chr10 GenomeTrafac similarity 6066610 6066697 . . .alignment;chr2:11635399-11635483chr10 GenomeTrafac similarity 6060184 6060222 . . .alignment;chr2:11634481-11634519chr10 GenomeTrafac similarity 6058019 6060221 . . .alignment;chr2:11632286-11634395chr10 GenomeTrafac similarity 6057199 6057554 . . .alignment;chr2:11631871-11632228chr10 GenomeTrafac similarity 6056544 6056681 . . .alignment;chr2:11618421-11618579chr10 GenomeTrafac similarity 6056612 6056672 . . .alignment;chr2:11622241-11622294chr10 GenomeTrafac similarity 6056135 6056267 . . .alignment;chr2:11616476-11616602chr10 GenomeTrafac similarity 6056069 6056145 . . .alignment;chr2:11613809-11613880track type=wiggle_0 name="Concise Alignments" description="Alignment Curve" color=200,100,0visibility=1 priority=5 maxHeightPixels=64:64:10 smoothingWindow=2 viewLimits=0.0:1.0 yLineMark=0.5yLineMark=onchr10 6056069 6056131 0.71chr10 6056135 6056163 0.55chr10 6056165 6056194 0.6chr10 6056201 6056204 1.0chr10 6056206 6056216 0.73chr10 6056219 6056222 1.0chr10 6056223 6056267 0.71chr10 6056544 6056599 0.64chr10 6056601 6056626 0.58chr10 6056627 6056636 0.8chr10 6056637 6056681 0.69chr10 6057199 6057245 0.55chr10 6057247 6057262 0.88chr10 6057269 6057281 0.69chr10 6057284 6057309 0.85chr10 6057310 6057369 0.67chr10 6057370 6057416 0.6chr10 6057420 6057468 0.59chr10 6057472 6057554 0.65chr10 6058019 6058046 0.64chr10 6058048 6058062 0.67chr10 6058064 6058090 0.63chr10 6058094 6058095 1.0chr10 6058098 6058120 0.48chr10 6058121 6058142 0.68chr10 6058150 6058164 0.73chr10 6058165 6058181 0.76chr10 6058182 6058195 0.71chr10 6058209 6058230 0.55chr10 6058231 6058237 0.86chr10 6058275 6058285 0.82chr10 6058290 6058338 0.59chr10 6058343 6058360 0.44chr10 6058361 6058385 0.8chr10 6058386 6058404 0.58chr10 6058406 6058423 0.83chr10 6058425 6058432 0.63chr10 6058435 6058462 0.75chr10 6058464 6058494 0.68chr10 6058497 6058510 0.71chr10 6058511 6058526 0.69chr10 6058528 6058585 0.59chr10 6058589 6058597 0.89chr10 6058598 6058606 0.89chr10 6058607 6058610 0.75chr10 6058611 6058625 0.73chr10 6058629 6058636 0.88chr10 6058639 6058653 0.67chr10 6058657 6058679 0.7chr10 6058685 6058696 0.67chr10 6058705 6058709 0.8chr10 6058719 6058744 0.58chr10 6058752 6058767 0.63chr10 6058770 6058779 0.8chr10 6058791 6058854 0.61chr10 6058855 6058859 0.8chr10 6058860 6058869 0.8chr10 6058870 6058883 0.5chr10 6058891 6058907 0.53chr10 6058909 6058949 0.76chr10 6058950 6058972 0.57chr10 6058974 6058988 0.6chr10 6058989 6058993 0.8chr10 6058996 6059003 0.75chr10 6059004 6059034 0.74chr10 6059059 6059096 0.58chr10 6059099 6059131 0.55chr10 6059132 6059157 0.69chr10 6059158 6059172 0.67chr10 6059173 6059179 0.71chr10 6059180 6059210 0.81chr10 6059213 6059233 0.57chr10 6059238 6059263 0.54chr10 6059266 6059282 0.41chr10 6059283 6059302 0.65chr10 6059303 6059335 0.55chr10 6059349 6059363 0.73chr10 6059364 6059400 0.81chr10 6059401 6059476 0.61chr10 6059477 6059489 0.69chr10 6059497 6059501 0.8chr10 6059506 6059592 0.72chr10 6059594 6059672 0.82chr10 6059673 6059687 0.53chr10 6059688 6059707 0.7chr10 6059716 6059725 0.7chr10 6059735 6059775 0.59chr10 6059781 6059788 0.63chr10 6059819 6059834 0.69chr10 6059858 6059885 0.68chr10 6059891 6059903 0.69chr10 6059904 6059909 0.67chr10 6059910 6059921 0.67chr10 6059922 6059929 0.75chr10 6059930 6059958 0.66chr10 6059959 6060026 0.62chr10 6060027 6060031 0.8chr10 6060032 6060035 1.0chr10 6060036 6060057 0.82chr10 6060058 6060079 0.5chr10 6060080 6060085 0.83chr10 6060086 6060091 1.0chr10 6060092 6060186 0.61chr10 6060187 6060221 0.69chr10 6066610 6066649 0.63chr10 6066650 6066659 1.0chr10 6066661 6066684 0.63chr10 6066687 6066697 0.82chr10 6066718 6066723 0.83chr10 6066731 6066746 0.75chr10 6066750 6066782 0.76chr10 6066784 6066804 0.71chr10 6070860 6070903 0.68chr10 6070906 6070917 0.67chr10 6070928 6070952 0.72chr10 6070963 6070970 0.75chr10 6070971 6070982 0.83chr10 6072688 6072740 0.68chr10 6072741 6072750 0.8chr10 6072751 6072777 0.52chr10 6072779 6072792 0.86chr10 6072794 6072815 0.68chr10 6077284 6077311 0.86chr10 6077321 6077347 0.56chr10 6077349 6077384 0.81chr10 6080429 6080490 0.66chr10 6081058 6081083 0.65chr10 6081087 6081105 0.58chr10 6081112 6081153 0.67chr10 6081156 6081199 0.68chr10 6081201 6081241 0.51chr10 6081244 6081309 0.53chr10 6081319 6081350 0.5chr10 6081351 6081414 0.75chr10 6081586 6081596 0.73chr10 6081597 6081607 0.64chr10 6081608 6081634 0.67chr10 6081640 6081643 1.0chr10 6081646 6081676 0.58chr10 6081685 6081707 0.52chr10 6081716 6081827 0.66chr10 6081829 6081853 0.68chr10 6081855 6081941 0.6chr10 6081942 6081949 0.88chr10 6081951 6081959 0.78chr10 6081961 6082028 0.59chr10 6082036 6082056 0.76chr10 6082058 6082066 0.67chr10 6082072 6082094 0.96chr10 6082099 6082152 0.57chr10 6082154 6082205 0.52chr10 6082206 6082216 0.82chr10 6082219 6082269 0.53chr10 6082274 6082302 0.69chr10 6082304 6082323 0.7chr10 6082400 6082464 0.57chr10 6082466 6082474 0.89chr10 6082477 6082528 0.65chr10 6082540 6082550 0.73chr10 6082553 6082568 0.75chr10 6082569 6082590 0.77chr10 6082840 6082876 1.0chr10 6082888 6082952 0.62chr10 6082953 6082965 0.54chr10 6082985 6083000 0.5chr10 6083005 6083047 0.88chr10 6083057 6083064 0.63chr10 6083071 6083141 0.77chr10 6083164 6083189 0.42chr10 6083194 6083238 0.89chr10 6083241 6083263 0.48chr10 6083280 6083323 0.86chr10 6086767 6086806 0.83chr10 6092552 6092601 0.56chr10 6092604 6092615 0.75chr10 6092616 6092635 0.75chr10 6092637 6092676 0.68chr10 6092677 6092691 0.93chr10 6092696 6092736 0.8chr10 6092743 6092798 0.68chr10 6092805 6092838 0.79chr10 6092879 6092902 0.75chr10 6092903 6092940 0.74chr10 6092941 6092956 0.69chr10 6092961 6092973 0.77chr10 6092976 6092985 0.7chr10 6092986 6092992 0.86chr10 6092996 6093030 0.69chr10 6093034 6093039 0.83chr10 6093049 6093058 0.6chr10 6093068 6093105 0.79chr10 6093110 6093119 1.0chr10 6093120 6093153 0.5chr10 6093169 6093173 1.0chr10 6093175 6093189 0.8chr10 6093192 6093251 0.67chr10 6093252 6093262 0.73chr10 6093263 6093278 0.69chr10 6093289 6093333 0.6chr10 6093334 6093362 0.55chr10 6093859 6093877 0.68chr10 6093879 6093901 0.83chr10 6093903 6093932 0.67chr10 6093944 6093960 0.59chr10 6093961 6094076 0.74chr10 6094090 6094094 1.0chr10 6094100 6094145 0.7chr10 6094146 6094153 0.63chr10 6094154 6094163 0.8chr10 6094164 6094266 0.75chr10 6094267 6094282 0.63chr10 6094287 6094299 0.85chr10 6094301 6094340 0.6chr10 6094341 6094348 0.63chr10 6094349 6094368 0.8chr10 6094413 6094431 0.89chr10 6094433 6094490 0.69chr10 6094492 6094519 0.61chr10 6094521 6094569 0.65chr10 6094570 6094651 0.52chr10 6094653 6094674 0.59chr10 6094685 6094712 0.71chr10 6094713 6094785 0.53chr10 6094799 6094818 0.6chr10 6094821 6094868 0.75chr10 6094869 6094915 0.51chr10 6094916 6094943 0.68chr10 6096268 6096300 0.61chr10 6096301 6096344 0.8chr10 6097028 6097079 0.71chr10 6100015 6100103 0.84chr10 6100104 6100166 0.57chr10 6100168 6100183 0.56chr10 6100184 6100191 0.88chr10 6100192 6100219 0.61chr10 6100231 6100267 0.62chr10 6100268 6100282 0.73chr10 6100292 6100305 0.64chr10 6100306 6100336 0.45chr10 6100337 6100365 0.76chr10 6100367 6100377 0.55chr10 6100382 6100411 0.63chr10 6100412 6100503 0.55chr10 6100513 6100520 0.63chr10 6100524 6100549 0.81chr10 6100551 6100575 0.56chr10 6100576 6100609 0.59chr10 6101329 6101364 0.64chr10 6101366 6101390 0.56chr10 6101391 6101536 0.64chr10 6101806 6101831 0.62chr10 6101832 6101945 0.65chr10 6101946 6101968 0.52chr10 6101969 6101979 0.64chr10 6101984 6102016 0.55chr10 6102017 6102045 0.52chr10 6102057 6102068 0.67chr10 6102070 6102084 0.73chr10 6102086 6102231 0.66chr10 6102349 6102366 0.67chr10 6102368 6102394 0.67chr10 6102395 6102463 0.65chr10 6102464 6102494 0.71chr10 6102814 6102824 0.82chr10 6102828 6102845 0.72chr10 6102847 6102880 0.62chr10 6102889 6102895 1.0chr10 6102900 6102928 0.55chr10 6102932 6102944 0.54chr10 6102948 6102958 0.64chr10 6102959 6102967 0.56chr10 6102969 6102983 0.67chr10 6102986 6102992 0.71chr10 6102995 6103007 0.62chr10 6103012 6103044 0.61chr10 6103057 6103072 0.63chr10 6103074 6103101 0.71chr10 6103102 6103140 0.67chr10 6103141 6103147 0.71chr10 6103148 6103181 0.62chr10 6103182 6103197 0.5chr10 6103199 6103210 0.75chr10 6103214 6103228 0.47chr10 6103230 6103241 0.67chr10 6103251 6103262 0.75chr10 6103285 6103300 0.63chr10 6103312 6103349 0.58chr10 6103361 6103373 0.62chr10 6103390 6103394 1.0chr10 6103398 6103410 0.62chr10 6103413 6103441 0.59chr10 6103443 6103679 0.73chr10 6103682 6103733 0.75chr10 6103734 6103764 0.68chr10 6103774 6103823 0.58chr10 6103827 6103828 1.0chr10 6103830 6103856 0.78chr10 6103859 6103902 0.75chr10 6103907 6103919 0.62chr10 6103922 6103934 0.77chr10 6103959 6103969 0.82chr10 6103977 6103982 0.67chr10 6103993 6104007 0.6chr10 6104012 6104017 1.0chr10 6104018 6104044 0.44chr10 6104045 6104063 0.84chr10 6104074 6104094 0.57chr10 6104100 6104143 0.61chr10 6104144 6104153 0.6chr10 6104154 6104176 0.52chr10 6104185 6104219 0.63chr10 6104220 6104244 0.84chr10 6104251 6104324 0.69chr10 6104325 6104347 0.61chr10 6104349 6104373 0.76chr10 6104374 6104470 0.59chr10 6104472 6104493 0.55chr10 6104494 6104544 0.59chr10 6104545 6104654 0.66chr10 6104658 6104711 0.61chr10 6104714 6104721 0.88chr10 6104724 6104730 0.86chr10 6104732 6104764 0.76chr10 6104767 6104781 0.67chr10 6104791 6104809 0.58chr10 6104810 6104846 0.62chr10 6104847 6104864 0.72chr10 6104865 6104878 0.79chr10 6104879 6104910 0.75chr10 6104911 6104953 0.7chr10 6104954 6105021 0.59chr10 6105039 6105100 0.5chr10 6105102 6105123 0.77chr10 6105126 6105134 0.78chr10 6105135 6105145 0.73chr10 6105146 6105155 0.7chr10 6105159 6105162 0.75chr10 6105163 6105176 0.64chr10 6105177 6105231 0.65chr10 6105232 6105245 0.64chr10 6105247 6105269 0.65chr10 6105606 6105632 0.67chr10 6105633 6105640 0.75chr10 6105642 6105655 0.64chr10 6105668 6105726 0.54chr10 6105751 6105775 0.72chr10 6105776 6105782 0.57chr10 6105786 6105834 0.63chr10 6105837 6105845 0.67chr10 6105847 6105867 0.71chr10 6105869 6105874 0.5chr10 6105876 6105901 0.58chr10 6105902 6105943 0.71chr10 6105944 6105958 0.8chr10 6105965 6105974 0.7chr10 6105980 6105988 0.67chr10 6106030 6106039 0.7chr10 6106044 6106053 0.8chr10 6106063 6106080 0.67chr10 6106082 6106090 0.78chr10 6106091 6106135 0.49chr10 6106173 6106196 0.67chr10 6106197 6106260 0.73chr10 6106261 6106367 0.68chr10 6106368 6106404 0.59chr10 6106408 6106425 0.78chr10 6106426 6106436 0.64chr10 6106449 6106468 0.65chr10 6107638 6107662 0.64chr10 6107663 6107687 0.72chr10 6107694 6107706 0.54chr10 6107707 6107750 0.61chr10 6107752 6107771 0.65chr10 6107773 6107793 0.57chr10 6107794 6107835 0.71chr10 6107848 6107877 0.67chr10 6107881 6108001 0.8chr10 6108003 6108029 0.56chr10 6108052 6108101 0.68chr10 6108102 6108108 0.86chr10 6108109 6108119 0.64chr10 6108622 6108655 0.62chr10 6108658 6108673 0.88chr10 6108683 6108693 0.82chr10 6108694 6108722 0.59chr10 6108724 6108730 0.86chr10 6108731 6108743 0.62chr10 6108746 6108796 0.73chr10 6112218 6112257 0.78chr10 6112258 6112286 0.66chr10 6112293 6112315 0.65chr10 6112316 6112333 0.72chr10 6112339 6112358 0.8chr10 6112360 6112461 0.7chr10 6112464 6112503 0.48chr10 6112504 6112574 0.69chr10 6112576 6112596 0.52chr10 6112597 6112672 0.67chr10 6112673 6112705 0.7chr10 6112717 6112729 0.77chr10 6112732 6112741 0.8chr10 6112742 6112770 0.72chr10 6112781 6112795 0.8chr10 6112798 6112938 0.62chr10 6112939 6112975 0.62chr10 6112990 6113012 0.57chr10 6113017 6113029 0.69chr10 6113030 6113042 0.69chr10 6113045 6113074 0.73chr10 6113075 6113081 0.86chr10 6113082 6113113 0.78chr10 6113121 6113149 0.76chr10 6113157 6113160 0.75chr10 6113168 6113197 0.63chr10 6113199 6113230 0.66chr10 6113232 6113247 0.94chr10 6113253 6113281 0.83chr10 6113282 6113305 0.83chr10 6113307 6113335 0.52chr10 6113336 6113380 0.71chr10 6113462 6113489 0.61chr10 6113497 6113508 0.83chr10 6113518 6113527 0.8chr10 6113531 6113572 0.64chr10 6113577 6113581 1.0chr10 6113583 6113614 0.63chr10 6113616 6113631 0.56chr10 6113634 6113653 0.6chr10 6113654 6113675 0.73chr10 6113678 6113732 0.65chr10 6113733 6113749 0.76chr10 6113754 6113772 0.47chr10 6113798 6113803 1.0chr10 6113805 6113821 0.76chr10 6113823 6113837 0.73chr10 6113854 6113872 0.79chr10 6113873 6113883 0.64chr10 6113887 6113906 0.75chr10 6113917 6113930 0.86chr10 6113933 6113966 0.59chr10 6113970 6113997 0.61chr10 6114007 6114040 0.44chr10 6114047 6114063 0.76chr10 6114065 6114118 0.67chr10 6114119 6114139 0.62chr10 6114140 6114165 0.58chr10 6114167 6114188 0.45chr10 6114189 6114220 0.59chr10 6114222 6114294 0.68chr10 6114295 6114303 0.78chr10 6114310 6114330 0.9chr10 6114667 6114690 0.63chr10 6114692 6114713 0.68chr10 6114714 6114730 0.82chr10 6114736 6114842 0.68chr10 6114843 6114852 0.5chr10 6114853 6114862 0.7chr10 6114863 6114879 0.59chr10 6114882 6114903 0.73chr10 6115306 6115345 0.7chr10 6115354 6115420 0.67chr10 6115421 6115444 0.63chr10 6115445 6115451 0.71chr10 6115452 6115468 0.59chr10 6115470 6115490 0.52chr10 6115492 6115533 0.71chr10 6115547 6115552 0.67chr10 6115557 6115602 0.57chr10 6115605 6115624 0.8chr10 6115637 6115654 0.78chr10 6115657 6115663 0.71chr10 6115665 6115669 1.0chr10 6115670 6115673 1.0chr10 6115674 6115690 0.76chr10 6115693 6115697 1.0chr10 6115698 6115715 0.5chr10 6115716 6115734 0.63chr10 6115735 6115755 0.9chr10 6115757 6115787 0.52chr10 6115788 6115793 0.67chr10 6115794 6115832 0.74chr10 6115837 6115849 0.85chr10 6115850 6115860 0.82chr10 6115894 6115938 0.73chr10 6115939 6115969 0.61chr10 6115971 6116063 0.56chr10 6116064 6116074 0.73chr10 6116080 6116097 0.78chr10 6116098 6116131 0.74chr10 6116133 6116165 0.79chr10 6116166 6116198 0.79chr10 6116199 6116224 0.77chr10 6116275 6116288 0.64chr10 6116289 6116311 0.78chr10 6116312 6116337 0.58chr10 6116340 6116357 0.72chr10 6116358 6116364 0.86chr10 6116365 6116417 0.68chr10 6116421 6116467 0.7chr10 6116469 6116478 0.8chr10 6116480 6116502 0.83chr10 6116503 6116515 0.54chr10 6116517 6116545 0.72chr10 6116549 6116555 0.71chr10 6116575 6116590 0.69chr10 6116591 6116604 0.57chr10 6116605 6116639 0.66chr10 6116641 6116652 0.75chr10 6116653 6116668 0.75chr10 6116672 6116693 0.68chr10 6118382 6118441 0.67chr10 6118462 6118471 0.5chr10 6118475 6118508 0.59chr10 6118546 6118564 0.58chr10 6118572 6118588 0.65chr10 6118594 6118642 0.63chr10 6118643 6118695 0.62chr10 6118697 6118754 0.62chr10 6118755 6118786 0.56chr10 6118789 6118801 0.62chr10 6118814 6118818 1.0chr10 6118843 6118874 0.5chr10 6118877 6118889 0.77chr10 6118896 6118904 0.67chr10 6118929 6118951 0.57chr10 6118952 6118969 0.5chr10 6118974 6118986 0.54chr10 6118991 6119011 0.67chr10 6119012 6119036 0.52chr10 6119037 6119043 0.57chr10 6119053 6119062 0.6chr10 6119064 6119079 0.88chr10 6119080 6119111 0.63chr10 6119122 6119138 0.65chr10 6119157 6119178 0.68chr10 6119182 6119192 0.73chr10 6119205 6119215 0.64chr10 6119226 6119250 0.72chr10 6119251 6119255 0.6chr10 6119262 6119294 0.55chr10 6119307 6119315 0.67chr10 6119316 6119352 0.7chr10 6119372 6119435 0.67chr10 6119436 6119449 0.71chr10 6119452 6119456 0.6chr10 6119471 6119486 0.69chr10 6119487 6119501 0.67chr10 6119506 6119517 0.67chr10 6119518 6119574 0.67chr10 6120139 6120144 1.0chr10 6120145 6120169 0.68chr10 6120170 6120204 0.54chr10 6120206 6120246 0.54chr10 6120247 6120282 0.75chr10 6120284 6120316 0.91chr10 6120320 6120337 0.83chr10 6120338 6120353 0.69chr10 6120354 6120388 0.6chr10 6120403 6120457 0.67chr10 6120459 6120497 0.64chr10 6120502 6120520 0.58chr10 6120522 6120537 0.69chr10 6120538 6120548 0.45chr10 6120553 6120558 1.0chr10 6120561 6120579 0.68chr10 6120580 6120631 0.75chr10 6120633 6120669 0.59chr10 6121740 6121813 0.64chr10 6121815 6121823 0.89chr10 6121824 6121846 0.74chr10 6121847 6121867 0.76chr10 6121875 6121887 0.62chr10 6121907 6121922 0.63chr10 6121930 6121971 0.62chr10 6124052 6124083 0.56chr10 6124084 6124111 0.75chr10 6124123 6124202 0.71chr10 6124210 6124214 0.8chr10 6124219 6124234 0.81chr10 6124236 6124256 0.52chr10 6124259 6124295 0.73chr10 6127131 6127141 0.64chr10 6127142 6127157 0.88chr10 6127159 6127175 0.88chr10 6127176 6127187 0.75chr10 6127190 6127225 0.69chr10 6127227 6127251 0.8chr10 6127252 6127259 1.0chr10 6127261 6127279 0.68chr10 6127280 6127286 0.86chr10 6127296 6127328 0.55chr10 6127334 6127372 0.56chr10 6127373 6127438 0.58chr10 6127439 6127460 0.59chr10 6127462 6127472 0.73chr10 6127476 6127548 0.85chr10 6127549 6127564 0.88chr10 6127565 6127577 0.62chr10 6127578 6127618 0.78chr10 6127619 6127700 0.8chr10 6127703 6127736 0.74chr10 6127737 6127748 0.58chr10 6127756 6127761 1.0chr10 6127762 6127780 0.74chr10 6132765 6132777 0.77chr10 6132778 6132807 0.57chr10 6132808 6132840 0.52chr10 6132841 6132874 0.59chr10 6132886 6132901 0.63chr10 6132907 6132915 0.67chr10 6132928 6132930 1.0chr10 6132938 6132948 0.91chr10 6132960 6132995 0.53chr10 6132997 6133024 0.71chr10 6133046 6133061 0.81chr10 6133063 6133067 1.0chr10 6133069 6133083 1.0chr10 6133085 6133102 0.89chr10 6133103 6133130 0.79chr10 6133131 6133179 0.78chr10 6133182 6133192 0.64chr10 6133202 6133216 0.8chr10 6133217 6133237 0.76chr10 6133239 6133262 0.75chr10 6133263 6133295 0.79chr10 6133297 6133376 0.8chr10 6133379 6133397 0.63chr10 6133398 6133431 0.65chr10 6133433 6133444 0.67chr10 6133454 6133465 0.67chr10 6133466 6133504 0.62chr10 6133853 6133891 0.69chr10 6133892 6133938 0.68chr10 6133939 6133950 0.58chr10 6133953 6133960 0.88chr10 6133973 6134000 0.57chr10 6134002 6134008 0.71chr10 6134017 6134047 0.71chr10 6134048 6134067 0.7chr10 6134078 6134156 0.56chr10 6134160 6134171 0.58chr10 6134172 6134184 0.92chr10 6134188 6134212 0.6chr10 6134213 6134224 0.75chr10 6134229 6134250 0.64chr10 6134252 6134288 0.68chr10 6134290 6134335 0.67chr10 6134340 6134351 0.75chr10 6134352 6134399 0.77chr10 6134410 6134425 0.75chr10 6134430 6134492 0.6chr10 6134493 6134499 0.86chr10 6134508 6134533 0.54chr10 6134534 6134540 0.86chr10 6134553 6134558 1.0chr10 6134569 6134579 0.55chr10 6134586 6134594 0.67chr10 6134624 6134670 0.72chr10 6134671 6134681 0.64chr10 6134682 6134763 0.89chr10 6134764 6134766 1.0chr10 6134767 6134813 0.89chr10 6134814 6134827 0.64chr10 6134833 6134844 0.83chr10 6134845 6134852 0.75chr10 6134853 6134858 1.0chr10 6134859 6134872 0.93chr10 6134889 6134960 0.6chr10 6136086 6136101 0.69chr10 6136102 6136107 1.0chr10 6136108 6136135 0.61chr10 6136148 6136162 0.73chr10 6136167 6136186 0.7chr10 6136197 6136245 0.65chr10 6136247 6136265 0.53chr10 6136266 6136286 0.71chr10 6136290 6136315 0.65chr10 6136317 6136324 0.88chr10 6136325 6136342 0.83chr10 6136344 6136442 0.56chr10 6136444 6136463 0.8chr10 6136642 6136706 0.68chr10 6136709 6136728 0.7chr10 6136731 6136780 0.7chr10 6136781 6136832 0.71chr10 6136968 6137002 0.74chr10 6137005 6137024 0.6chr10 6137025 6137036 0.92chr10 6137038 6137081 0.68chr10 6137082 6137094 0.92chr10 6137096 6137113 0.61chr10 6137114 6137120 0.86chr10 6137124 6137130 0.71chr10 6137133 6137137 1.0chr10 6137140 6137168 0.62chr10 6137178 6137199 0.82chr10 6137242 6137259 0.72chr10 6137260 6137355 0.58chr10 6137356 6137371 0.63chr10 6137372 6137383 0.83chr10 6137918 6138011 0.67chr10 6138012 6138021 0.8chr10 6138022 6138085 0.67chr10 6138086 6138131 0.61chr10 6138132 6138147 0.56chr10 6138148 6138191 0.68chr10 6138193 6138199 0.71chr10 6138214 6138266 0.77chr10 6138267 6138284 0.83chr10 6138285 6138311 0.67chr10 6138390 6138437 0.77chr10 6139202 6139218 0.76chr10 6139220 6139239 0.75chr10 6139241 6139253 0.77chr10 6139255 6139262 1.0chr10 6139263 6139277 0.47chr10 6139278 6139291 0.64chr10 6139292 6139306 0.67chr10 6139307 6139358 0.6chr10 6139359 6139391 0.61chr10 6139392 6139426 0.71chr10 6139427 6139500 0.68chr10 6139501 6139541 0.66chr10 6139542 6139563 0.5chr10 6139564 6139627 0.58chr10 6139628 6139645 0.56chr10 6139648 6139727 0.63chr10 6139736 6139802 0.58chr10 6139803 6139810 0.88chr10 6140186 6140215 0.63chr10 6140216 6140261 0.57chr10 6140286 6140301 0.69chr10 6140303 6140324 0.77chr10 6140326 6140352 0.63chr10 6140357 6140369 0.69chr10 6140376 6140386 0.64chr10 6140387 6140431 0.62chr10 6140433 6140455 0.52chr10 6140456 6140488 0.76chr10 6140496 6140513 0.56chr10 6140515 6140524 0.7chr10 6140545 6140646 0.69chr10 6140658 6140671 0.86chr10 6140672 6140707 0.92chr10 6140712 6140725 0.86chr10 6140733 6140779 0.81chr10 6140780 6140795 0.75chr10 6140796 6140807 1.0chr10 6140809 6140870 0.84chr10 6140871 6140929 0.81chr10 6140931 6140968 0.97chr10 6140969 6140988 0.85chr10 6140989 6141017 0.72chr10 6141020 6141038 0.74chr10 6141039 6141083 0.6chr10 6141085 6141105 0.52chr10 6141114 6141130 0.65chr10 6141132 6141152 0.76chr10 6141178 6141231 0.74chr10 6141242 6141260 0.63chr10 6141264 6141275 0.67chr10 6141288 6141310 0.52chr10 6141321 6141340 0.75chr10 6141347 6141383 0.76chr10 6141386 6141406 0.52chr10 6141407 6141446 0.58chr10 6141447 6141486 0.68chr10 6141487 6141495 0.67chr10 6141496 6141501 1.0chr10 6141502 6141513 0.5chr10 6141514 6141529 0.56chr10 6141530 6141552 0.61chr10 6141553 6141566 0.64chr10 6141571 6141586 0.69chr10 6141587 6141606 0.65chr10 6141609 6141620 0.83chr10 6141628 6141636 0.67chr10 6141641 6141647 0.71chr10 6141656 6141692 0.57chr10 6141695 6141716 0.5chr10 6141717 6141740 0.71chr10 6141742 6141787 0.76chr10 6141807 6141814 0.88chr10 6141827 6141845 0.58chr10 6141859 6141869 0.64chr10 6141872 6141875 1.0chr10 6141881 6141884 1.0chr10 6141894 6141910 0.53chr10 6141929 6141940 0.67chr10 6141941 6141952 0.92chr10 6142000 6142014 0.6chr10 6142015 6142041 0.67chr10 6142045 6142114 0.69chr10 6142116 6142145 0.63chr10 6142146 6142149 1.0chr10 6142150 6142184 0.77chr10 6142929 6142946 0.67chr10 6142947 6142954 0.75chr10 6142958 6142982 0.68chr10 6142984 6143048 0.74chr10 6143049 6143064 0.94chr10 6143832 6143842 0.82chr10 6143843 6143849 0.86chr10 6143850 6144017 0.65chr10 6144018 6144050 0.61chr10 6144051 6144140 0.73chr10 6144141 6144183 0.58chr10 6144190 6144214 0.64chr10 6144215 6144261 0.51chr10 6144264 6144326 0.7chr10 6144328 6144336 0.78chr10 6144337 6144340 1.0chr10 6144344 6144361 0.83chr10 6144364 6144389 1.0chr10 6144397 6144430 0.97chr10 6144432 6144456 0.96chr10 6144457 6144543 0.76chr10 6144545 6144619 0.83chr10 6147549 6147568 0.7chr10 6147569 6147593 0.72chr10 6147594 6147610 0.88chr10 6147612 6147624 0.62chr10 6147627 6147651 0.68chr10 6147659 6147705 0.74chr10 6147708 6147726 0.74chr10 6147727 6147739 0.69chr10 6147740 6147762 0.83chr10 6147764 6147852 0.78chr10 6147872 6147884 0.77chr10 6147885 6147913 0.66chr10 6147936 6147962 0.78chr10 6147963 6147973 0.82chr10 6147974 6147994 0.62chr10 6147995 6148008 0.93chr10 6148010 6148118 0.81chr10 6148119 6148157 0.54chr10 6148158 6148171 0.71chr10 6148172 6148236 0.57chr10 6148237 6148330 0.65chr10 6148331 6148386 0.68chr10 6148400 6148434 0.57chr10 6149776 6149836 0.64chr10 6149849 6149868 0.55chr10 6149869 6149884 0.69chr10 6149889 6149906 0.61chr10 6149907 6149918 0.75chr10 6149922 6149931 0.8chr10 6149933 6149966 0.74chr10 6149967 6150014 0.6chr10 6150016 6150027 0.67chr10 6150029 6150047 0.58chr10 6150048 6150081 0.53chr10 6150320 6150387 0.69chr10 6150388 6150420 0.61chr10 6150427 6150451 0.52chr10 6150462 6150524 0.71chr10 6150532 6150556 0.64chr10 6150558 6150571 0.64chr10 6150572 6150607 0.78chr10 6150610 6150621 0.75chr10 6150625 6150671 0.7chr10 6150717 6150723 0.57chr10 6150725 6150760 0.53chr10 6150763 6150784 0.73chr10 6150788 6150801 0.64chr10 6150806 6150810 0.8chr10 6150818 6150843 0.58chr10 6150845 6150895 0.57chr10 6150910 6150928 0.74chr10 6150929 6150963 0.63chr10 6150965 6150973 0.67chr10 6150977 6151013 0.68chr10 6151032 6151043 0.67chr10 6151046 6151050 0.8chr10 6151051 6151073 0.65chr10 6151075 6151082 0.63chr10 6151085 6151115 0.55chr10 6151123 6151142 0.65chr10 6151143 6151151 0.56chr10 6151152 6151184 0.55chr10 6151186 6151229 0.48chr10 6151230 6151363 0.8chr10 6151365 6151397 0.88chr10 6151407 6151477 0.69chr10 6151478 6151481 0.75chr10 6151484 6151522 0.69chr10 6151523 6151527 0.8chr10 6151532 6151556 0.72chr10 6151559 6151593 0.57chr10 6151595 6151616 0.64chr10 6151696 6151751 0.71chr10 6151752 6151777 0.81chr10 6151779 6151812 0.44chr10 6151816 6151823 0.75chr10 6151826 6151842 0.71chr10 6151843 6151887 0.87chr10 6151888 6151922 0.69chr10 6151926 6151944 0.63chr10 6152599 6152631 0.58chr10 6152634 6152653 0.85chr10 6152657 6152677 0.57chr10 6152679 6152740 0.66chr10 6152741 6152799 0.61chr10 6152801 6152852 0.67chr10 6152861 6152896 0.53chr10 6152899 6152954 0.75chr10 6152955 6152969 0.6chr10 6152972 6153020 0.61chr10 6153021 6153030 0.7chr10 6153031 6153082 0.62chr10 6153098 6153132 0.74chr10 6154358 6154383 0.77chr10 6154384 6154405 0.5chr10 6154406 6154459 0.52chr10 6154460 6154506 0.6chr10 6154508 6154522 0.67chr10 6154527 6154542 0.56chr10 6154551 6154569 0.84chr10 6154602 6154613 0.67chr10 6154614 6154627 0.64chr10 6154633 6154660 0.68chr10 6154661 6154690 0.63chr10 6154692 6154753 0.66chr10 6154755 6154781 0.89chr10 6154782 6154798 0.76chr10 6154801 6154834 0.68chr10 6154837 6154849 0.62chr10 6154851 6154864 0.57chr10 6154876 6154897 0.64chr10 6154901 6154925 0.6chr10 6154926 6154953 0.61chr10 6156249 6156257 1.0chr10 6156263 6156322 0.72chr10 6156323 6156346 0.63chr10 6156348 6156363 0.69chr10 6156364 6156413 0.64chr10 6156418 6156446 0.59chr10 6156449 6156458 0.8chr10 6156459 6156463 1.0chr10 6156465 6156527 0.65chr10 6156538 6156549 0.67chr10 6156555 6156595 0.56chr10 6157071 6157092 0.55chr10 6157093 6157126 0.74chr10 6157134 6157158 0.56chr10 6157159 6157163 1.0chr10 6157165 6157186 0.73chr10 6157187 6157207 0.57chr10 6158173 6158223 0.71chr10 6158225 6158250 0.73chr10 6158251 6158260 0.7chr10 6158261 6158339 0.65chr10 6160358 6160399 0.55chr10 6160400 6160421 0.64chr10 6160422 6160523 0.71chr10 6160524 6160539 0.69chr10 6160540 6160544 0.8chr10 6160548 6160573 0.69chr10 6160577 6160588 0.67chr10 6160594 6160601 0.75chr10 6160614 6160631 0.72chr10 6160632 6160700 0.71chr10 6165209 6165251 0.63chr10 6165253 6165258 1.0chr10 6165259 6165266 0.75chr10 6165267 6165281 0.53chr10 6165294 6165316 0.61chr10 6165322 6165423 0.64chr10 6165424 6165462 0.59chr10 6165463 6165487 0.68chr10 6165489 6165501 0.77chr10 6165505 6165527 0.65chr10 6165528 6165577 0.72chr10 6165579 6165618 0.7chr10 6165646 6165650 1.0chr10 6165677 6165717 0.56chr10 6165729 6165765 0.49chr10 6165770 6165821 0.62chr10 6165822 6165830 0.67chr10 6165832 6165890 0.97chr10 6165891 6165905 0.53chr10 6165908 6165929 0.91chr10 6165930 6165978 0.78chr10 6165991 6165999 0.78chr10 6166002 6166024 0.65chr10 6166026 6166076 0.69chr10 6166079 6166106 0.5chr10 6166108 6166129 0.68chr10 6166132 6166144 0.85chr10 6166146 6166155 0.9chr10 6166163 6166171 0.89chr10 6166173 6166197 0.72chr10 6166200 6166213 0.86chr10 6166348 6166386 0.82chr10 6166388 6166412 0.76chr10 6166420 6166449 0.53chr10 6166452 6166527 0.63chr10 6167355 6167390 0.64chr10 6167393 6167437 0.78chr10 6167439 6167464 0.77chr10 6167465 6167474 0.8chr10 6167475 6167556 0.52chr10 6167557 6167570 0.71chr10 6167572 6167590 0.84chr10 6167600 6167623 0.5chr10 6167630 6167644 0.47chr10 6167646 6167653 0.63chr10 6167654 6167666 0.69chr10 6167668 6167722 0.58chr10 6167723 6167763 0.59chr10 6167764 6167772 0.89chr10 6167859 6167880 0.91chr10 6167882 6167907 0.77chr10 6167917 6167944 0.82chr10 6167945 6167957 0.92chr10 6167958 6167989 0.66chr10 6167999 6168011 0.77chr10 6168013 6168041 0.76chr10 6168051 6168076 0.42chr10 6168081 6168107 0.59chr10 6168109 6168157 0.78chr10 6169661 6169725 0.72chr10 6169726 6169744 0.74chr10 6169757 6169773 0.71chr10 6169775 6169781 1.0chr10 6169792 6169804 1.0chr10 6169817 6169829 0.62chr10 6169838 6169846 0.78chr10 6169851 6169861 0.45chr10 6169863 6169880 0.78chr10 6169881 6169903 0.57chr10 6169905 6169930 0.77chr10 6169931 6169937 1.0chr10 6170430 6170457 0.68chr10 6170460 6170509 0.66chr10 6170514 6170536 0.61chr10 6170537 6170546 0.6chr10 6170548 6170568 0.86chr10 6170569 6170581 0.69chr10 6170583 6170599 0.59chr10 6170619 6170629 0.55chr10 6170635 6170652 0.83chr10 6170655 6170705 0.67chr10 6170717 6170723 1.0chr10 6170741 6170758 0.56chr10 6170769 6170777 0.78chr10 6170780 6170796 0.47chr10 6170818 6170839 0.73chr10 6170840 6170853 0.86chr10 6170867 6170881 0.87chr10 6170883 6170919 0.78chr10 6170938 6170948 0.73chr10 6170954 6170957 1.0chr10 6170958 6171184 0.73chr10 6171186 6171199 0.64chr10 6171200 6171205 0.83chr10 6171206 6171226 0.76chr10 6171228 6171261 0.85chr10 6171262 6171272 0.82chr10 6171273 6171304 0.63chr10 6171305 6171318 0.71chr10 6171319 6171331 0.69chr10 6171348 6171371 0.63chr10 6171374 6171380 0.86#conserved TF binding sites NM_000417:NM_008367track name="TF Binding Sites" description="Conserved TF binding sites on this gene." color=30,144,255visibility=1 priority=6 useScore=0# 128147:128209# 128133:128141# 128115:128143# 128084:128113# 128074:128077# 128062:128072# 128056:128059# 128011:128055# 127679:127734chr10 GenomeTrafac regulation 6056574 6056598 . . . V$TBX5.01:0# 127652:127677# 127651:127666# 127642:127651# 127606:127643# 127597:127641# 127033:127079chr10 GenomeTrafac regulation 6057218 6057238 . . . V$ISL1.01:1chr10 GenomeTrafac regulation 6057220 6057236 . . . V$GSH1.01:2# 127016:127031# 126997:127009# 126969:126994# 126909:126968# 126862:126908# 126810:126858chr10 GenomeTrafac regulation 6057422 6057434 . . . V$MYT1L.01:3# 126724:126806# 126232:126259# 126216:126230# 126188:126214# 126183:126184# 126158:126180# 126136:126157# 126114:126128# 126097:126113# 126083:126096# 126048:126069# 126041:126047# 125993:126003# 125940:125988# 125918:125935# 125893:125917# 125874:125892# 125855:125872# 125846:125853# 125816:125843# 125784:125814# 125768:125781# 125752:125767# 125693:125750chr10 GenomeTrafac regulation 6058534 6058556 . . . V$MEF2.05:4chr10 GenomeTrafac regulation 6058538 6058554 . . . V$XFD2.01:5chr10 GenomeTrafac regulation 6058539 6058555 . . . V$TATA.01:6# 125681:125689# 125672:125680# 125668:125671# 125653:125667# 125642:125649# 125625:125639# 125599:125621# 125582:125593# 125569:125573# 125534:125559# 125511:125526# 125499:125508# 125424:125487# 125419:125423# 125409:125418# 125395:125408# 125371:125387# 125329:125369# 125306:125328# 125290:125304# 125285:125289# 125275:125282# 125244:125274# 125182:125219# 125147:125179# 125121:125146chr10 GenomeTrafac regulation 6059133 6059147 . . . V$HIF1.02:7# 125106:125120# 125099:125105# 125068:125098chr10 GenomeTrafac regulation 6059188 6059202 . . . V$CLOCK_BMAL1.01:8chr10 GenomeTrafac regulation 6059188 6059202 . . . V$USF.01:9chr10 GenomeTrafac regulation 6059189 6059203 . . . V$USF.01:10chr10 GenomeTrafac regulation 6059189 6059203 . . . V$ARNT.01:11# 125045:125065# 125015:125040# 124996:125012# 124976:124995# 124943:124975# 124915:124929# 124878:124914chr10 GenomeTrafac regulation 6059372 6059382 . . . V$WHN.01:12# 124802:124877# 124789:124801# 124777:124781# 124686:124772chr10 GenomeTrafac regulation 6059557 6059575 . . . V$IRF7.01:13chr10 GenomeTrafac regulation 6059563 6059581 . . . V$IRF1.01:14# 124606:124684chr10 GenomeTrafac regulation 6059616 6059624 . . . V$MEIS1.01:15chr10 GenomeTrafac regulation 6059619 6059643 . . . V$BACH2.01:16chr10 GenomeTrafac regulation 6059619 6059643 . . . V$NFE2.01:17chr10 GenomeTrafac regulation 6059622 6059642 . . . V$TAXCREB.02:18chr10 GenomeTrafac regulation 6059626 6059636 . . . V$AP1.01:19chr10 GenomeTrafac regulation 6059626 6059636 . . . V$AP1.01:20chr10 GenomeTrafac regulation 6059634 6059656 . . . V$ZF9.01:21chr10 GenomeTrafac regulation 6059636 6059650 . . . V$GC.01:22chr10 GenomeTrafac regulation 6059636 6059648 . . . V$MAZR.01:23chr10 GenomeTrafac regulation 6059636 6059648 . . . V$BKLF.01:24chr10 GenomeTrafac regulation 6059638 6059644 . . . V$MZF1.01:25# 124591:124605# 124571:124590# 124553:124562# 124503:124543# 124490:124497# 124444:124459# 124393:124420# 124375:124387# 124369:124374# 124357:124368# 124349:124356# 124320:124348# 124252:124319# 124247:124251# 124243:124246# 124221:124242# 124199:124220# 124193:124198# 124187:124192# 124092:124186# 124057:124091chr10 GenomeTrafac regulation 6060195 6060207 . . . V$MAZ.01:26chr10 GenomeTrafac regulation 6060201 6060207 . . . V$MZF1.01:27# 124056:124094chr10 GenomeTrafac regulation 6060184 6060206 . . . V$ZBP89.01:28chr10 GenomeTrafac regulation 6060194 6060216 . . . V$ZBP89.01:29chr10 GenomeTrafac regulation 6060195 6060207 . . . V$MAZ.01:30chr10 GenomeTrafac regulation 6060201 6060207 . . . V$MZF1.01:31# 117629:117668# 117620:117652# 117619:117628# 117595:117617# 117594:117617# 117581:117591# 117561:117583# 117555:117560# 117532:117547# 117496:117528# 117474:117494# 113375:113418# 113361:113372# 113326:113350# 113308:113315# 113296:113307# 111538:111590# 111528:111537# 111501:111527# 111486:111499# 111463:111484# 106967:106994# 106931:106957# 106894:106929# 103788:103849# 103195:103220# 103173:103191# 103125:103166# 103079:103122# 103037:103077# 102969:103034# 102928:102959# 102864:102927chr10 GenomeTrafac regulation 6081378 6081394 . . . V$HNF1.02:32chr10 GenomeTrafac regulation 6081383 6081399 . . . V$HOX1-3.01:33chr10 GenomeTrafac regulation 6081383 6081397 . . . V$LMX1B.01:34chr10 GenomeTrafac regulation 6081386 6081398 . . . V$BRIGHT.01:35# 102682:102692# 102671:102681# 102644:102670# 102635:102638# 102602:102632# 102571:102593# 102451:102562# 102425:102449# 102337:102423# 102329:102336# 102319:102327# 102250:102317# 102222:102242# 102212:102220# 102184:102206# 102126:102179# 102073:102124# 102062:102072# 102009:102059# 101976:102004# 101955:101974# 101814:101878# 101804:101812# 101750:101801chr10 GenomeTrafac regulation 6082510 6082524 . . . V$OCT1.02:36# 101728:101738# 101710:101725# 101688:101709# 101402:101438# 101326:101390# 101326:101350# 101313:101325# 101278:101293# 101231:101273# 101231:101263# 101214:101221# 101137:101207# 101137:101178# 101089:101114# 101041:101074# 101040:101084# 101040:101075# 101015:101037# 100955:100998# 100939:101030# 97472:97511chr10 GenomeTrafac regulation 6086769 6086793 . . . V$GAGA.01:37chr10 GenomeTrafac regulation 6086771 6086795 . . . V$GAGA.01:38chr10 GenomeTrafac regulation 6086777 6086801 . . . V$GAGA.01:39chr10 GenomeTrafac regulation 6086779 6086803 . . . V$GAGA.01:40chr10 GenomeTrafac regulation 6086781 6086805 . . . V$GAGA.01:41# 91677:91726# 91663:91674# 91643:91662# 91602:91641# 91587:91601# 91542:91582chr10 GenomeTrafac regulation 6092696 6092712 . . . V$BRN3.01:42chr10 GenomeTrafac regulation 6092706 6092722 . . . V$XFD3.01:43chr10 GenomeTrafac regulation 6092707 6092723 . . . V$XFD3.01:44# 91480:91535chr10 GenomeTrafac regulation 6092755 6092765 . . . V$HSF1.01:45chr10 GenomeTrafac regulation 6092756 6092766 . . . V$HSF1.01:46chr10 GenomeTrafac regulation 6092758 6092766 . . . V$MTBF.01:47# 91440:91473# 91376:91399# 91338:91375# 91322:91337# 91305:91317# 91293:91302# 91286:91292# 91248:91282# 91239:91244# 91220:91229# 91173:91210# 91159:91168# 91125:91158# 91105:91109# 91089:91103# 91027:91086# 91016:91026# 91000:91015# 90945:90989# 90916:90944# 90401:90419# 90377:90399# 90346:90375# 90318:90334# 90202:90317chr10 GenomeTrafac regulation 6093985 6094001 . . . V$XVENT2.01:48# 90184:90188# 90133:90178# 90125:90132# 90115:90124# 90012:90114chr10 GenomeTrafac regulation 6094180 6094190 . . . V$HSF1.01:49# 89996:90011# 89979:89991# 89938:89977chr10 GenomeTrafac regulation 6094311 6094325 . . . V$CEBPB.01:50# 89930:89937# 89910:89929# 89847:89865chr10 GenomeTrafac regulation 6094415 6094425 . . . V$VBP.01:51# 89788:89845# 89759:89786# 89709:89757# 89627:89708chr10 GenomeTrafac regulation 6094574 6094588 . . . V$AML3.01:52# 89604:89625# 89566:89593# 89493:89565chr10 GenomeTrafac regulation 6094727 6094737 . . . V$VMYB.02:53chr10 GenomeTrafac regulation 6094757 6094771 . . . V$GFI1.01:54# 89460:89479# 89410:89457chr10 GenomeTrafac regulation 6094852 6094868 . . . V$ELF2.01:55# 89363:89409# 89335:89362# 87978:88010# 87934:87977# 87199:87250# 84175:84263chr10 GenomeTrafac regulation 6100086 6100094 . . . V$MEIS1.01:56# 84112:84174# 84095:84110# 84087:84094# 84059:84086# 84011:84047# 83996:84010# 83973:83986# 83942:83972# 83913:83941chr10 GenomeTrafac regulation 6100340 6100360 . . . V$MOK2.02:57# 83901:83911# 83867:83896# 83775:83866# 83758:83765# 83729:83754# 83703:83727# 83669:83702# 82914:82949# 82888:82912# 82742:82887# 82447:82472# 82333:82446chr10 GenomeTrafac regulation 6101851 6101867 . . . V$ETS1.01:58# 82310:82332# 82299:82309# 82262:82294# 82233:82261# 82210:82221# 82194:82208# 82047:82192chr10 GenomeTrafac regulation 6102131 6102143 . . . V$EKLF.01:59# 81912:81929# 81884:81910# 81815:81883chr10 GenomeTrafac regulation 6102416 6102438 . . . V$OLF1.01:60chr10 GenomeTrafac regulation 6102417 6102439 . . . V$OLF1.01:61# 81784:81814# 81454:81464# 81433:81450# 81398:81431# 81383:81389# 81350:81378# 81334:81346# 81320:81330# 81311:81319# 81295:81309# 81286:81292# 81271:81283# 81234:81266# 81206:81221# 81177:81204# 81138:81176# 81131:81137# 81097:81130# 81081:81096# 81068:81079# 81050:81064# 81037:81048# 81016:81027# 80978:80993# 80929:80966# 80905:80917# 80884:80888# 80868:80880# 80837:80865# 80599:80835chr10 GenomeTrafac regulation 6103582 6103598 . . . V$TAL1ALPHAE47.01:62chr10 GenomeTrafac regulation 6103597 6103613 . . . V$EVI1.05:63chr10 GenomeTrafac regulation 6103628 6103642 . . . V$RBPJK.02:64chr10 GenomeTrafac regulation 6103653 6103669 . . . V$RORA1.01:65# 80545:80596# 80514:80544# 80455:80504# 80450:80451# 80422:80448# 80376:80419# 80359:80371# 80344:80356# 80309:80319# 80296:80301# 80271:80285# 80261:80266# 80234:80260# 80215:80233# 80184:80204# 80135:80178# 80125:80134# 80102:80124# 80059:80093# 80034:80058# 79954:80027# 79931:79953# 79905:79929# 79808:79904chr10 GenomeTrafac regulation 6104403 6104415 . . . V$IK3.01:66# 79785:79806# 79734:79784chr10 GenomeTrafac regulation 6104505 6104519 . . . V$RREB1.01:67# 79624:79733chr10 GenomeTrafac regulation 6104560 6104576 . . . V$CETS1P54.01:68chr10 GenomeTrafac regulation 6104567 6104581 . . . V$ATF6.01:69chr10 GenomeTrafac regulation 6104568 6104582 . . . V$GLI1.01:70# 79567:79620chr10 GenomeTrafac regulation 6104695 6104707 . . . V$CHR.01:71# 79557:79564# 79548:79554# 79514:79546# 79497:79511# 79491:79502# 79469:79487# 79432:79468chr10 GenomeTrafac regulation 6104820 6104830 . . . V$VMYB.01:72# 79414:79431# 79400:79413# 79368:79399chr10 GenomeTrafac regulation 6104879 6104897 . . . V$STAT1.01:73# 79325:79367# 79257:79324chr10 GenomeTrafac regulation 6104977 6104989 . . . V$NKX31.01:74chr10 GenomeTrafac regulation 6105002 6105014 . . . V$NKX31.01:75# 79178:79239# 79155:79176# 79144:79152# 79133:79143# 79123:79132# 79116:79119# 79102:79115# 79047:79101chr10 GenomeTrafac regulation 6105200 6105218 . . . V$CDX2.01:76# 79033:79046# 79009:79031# 78646:78672# 78638:78645# 78623:78636# 78552:78610# 78503:78527# 78496:78502# 78444:78492# 78433:78441# 78411:78431# 78404:78409# 78377:78402# 78335:78376# 78320:78334# 78304:78313# 78290:78298# 78239:78248# 78225:78234# 78198:78215# 78188:78196# 78143:78187# 78082:78105# 78018:78081# 77911:78017# 77874:77910# 77853:77870# 77842:77852# 77810:77829# 76616:76640# 76591:76615# 76572:76584# 76528:76571chr10 GenomeTrafac regulation 6107721 6107737 . . . V$XFD3.01:77# 76507:76526# 76485:76505# 76443:76484# 76401:76430# 76277:76397chr10 GenomeTrafac regulation 6107897 6107911 . . . V$OCT1.02:78chr10 GenomeTrafac regulation 6107941 6107957 . . . V$LEF1.02:79chr10 GenomeTrafac regulation 6107944 6107956 . . . V$CHR.01:80# 76249:76275# 76177:76226# 76170:76176# 76159:76169# 75623:75656# 75605:75620# 75585:75595# 75556:75584# 75548:75554# 75535:75547# 75482:75532# 72021:72060# 71992:72020# 71963:71985# 71945:71962# 71920:71939# 71817:71918chr10 GenomeTrafac regulation 6112437 6112453 . . . V$GSH1.01:81# 71775:71814# 71704:71774chr10 GenomeTrafac regulation 6112557 6112569 . . . V$MYT1L.01:82# 71682:71702# 71606:71681chr10 GenomeTrafac regulation 6112615 6112633 . . . V$IRF1.01:83chr10 GenomeTrafac regulation 6112618 6112638 . . . V$ISL1.01:84chr10 GenomeTrafac regulation 6112620 6112632 . . . V$DLX3.01:85chr10 GenomeTrafac regulation 6112621 6112635 . . . V$TST1.01:86chr10 GenomeTrafac regulation 6112653 6112669 . . . V$HOX1-3.01:87# 71573:71605# 71549:71561# 71537:71546# 71508:71536# 71483:71497# 71340:71480chr10 GenomeTrafac regulation 6112839 6112861 . . . V$MEF2.05:88chr10 GenomeTrafac regulation 6112869 6112881 . . . V$NKX25.02:89# 71303:71339# 71266:71288# 71249:71261# 71236:71248# 71204:71233# 71197:71203# 71165:71196chr10 GenomeTrafac regulation 6113083 6113103 . . . V$PDX1.01:90# 71129:71157chr10 GenomeTrafac regulation 6113128 6113146 . . . V$ISRE.01:91chr10 GenomeTrafac regulation 6113133 6113145 . . . V$MYT1L.01:92# 71118:71121# 71081:71110# 71048:71079chr10 GenomeTrafac regulation 6113205 6113221 . . . V$CDPCR3.01:93# 71031:71046# 70997:71025chr10 GenomeTrafac regulation 6113255 6113267 . . . V$GATA1.02:94chr10 GenomeTrafac regulation 6113256 6113270 . . . V$OCT1.01:95# 70973:70996# 70943:70971# 70898:70942# 70789:70816# 70770:70781# 70751:70760# 70706:70747chr10 GenomeTrafac regulation 6113532 6113540 . . . V$S8.01:96chr10 GenomeTrafac regulation 6113533 6113549 . . . V$XVENT2.01:97chr10 GenomeTrafac regulation 6113539 6113553 . . . V$LHX3.01:98chr10 GenomeTrafac regulation 6113539 6113551 . . . V$BRIGHT.01:99# 70697:70701# 70664:70695# 70647:70662# 70625:70644# 70603:70624# 70546:70600chr10 GenomeTrafac regulation 6113695 6113717 . . . V$MEF2.05:100chr10 GenomeTrafac regulation 6113696 6113712 . . . V$TATA.01:101chr10 GenomeTrafac regulation 6113697 6113713 . . . V$XFD2.01:102# 70529:70545# 70506:70524# 70475:70480# 70457:70473# 70441:70455# 70406:70424# 70395:70405# 70372:70391# 70348:70361# 70312:70345# 70281:70308# 70238:70271# 70215:70231# 70160:70213chr10 GenomeTrafac regulation 6114106 6114116 . . . V$PIT1.01:103# 70139:70159# 70113:70138# 70090:70111# 70058:70089# 69984:70056chr10 GenomeTrafac regulation 6114276 6114292 . . . V$EVI1.04:104# 69975:69983# 69948:69968# 69588:69611# 69565:69586# 69548:69564# 69436:69542# 69426:69435# 69416:69425# 69399:69415# 69375:69396# 68933:68972# 68858:68924# 68834:68857# 68827:68833# 68810:68826# 68788:68808# 68745:68786# 68726:68731# 68676:68721chr10 GenomeTrafac regulation 6115566 6115578 . . . V$CHR.01:105# 68654:68673# 68624:68641# 68615:68621# 68609:68613# 68605:68608# 68588:68604# 68581:68585# 68563:68580# 68544:68562# 68523:68543# 68491:68521# 68485:68490# 68446:68484chr10 GenomeTrafac regulation 6115810 6115816 . . . V$TGIF.01:106# 68429:68441# 68418:68428# 68392:68430# 68340:68384chr10 GenomeTrafac regulation 6115899 6115919 . . . V$HLF.01:107# 68309:68339chr10 GenomeTrafac regulation 6115957 6115965 . . . V$MTBF.01:108# 68215:68307chr10 GenomeTrafac regulation 6115988 6116002 . . . V$CEBPB.01:109# 68204:68214# 68181:68198# 68147:68180# 68113:68145# 68080:68112# 68054:68079# 67990:68003# 67967:67989# 67941:67966# 67921:67938# 67914:67920# 67861:67913# 67811:67857# 67800:67809# 67776:67798# 67763:67775# 67733:67761# 67723:67729# 67688:67703# 67674:67687# 67639:67673# 67626:67637# 67610:67625# 67585:67606# 65837:65896# 65807:65816# 65770:65803# 65714:65732# 65690:65706# 65636:65684# 65583:65635chr10 GenomeTrafac regulation 6118671 6118687 . . . V$GSH1.01:110chr10 GenomeTrafac regulation 6118671 6118683 . . . V$MSX.01:111chr10 GenomeTrafac regulation 6118672 6118688 . . . V$GSH1.01:112chr10 GenomeTrafac regulation 6118672 6118686 . . . V$LHX3.01:113chr10 GenomeTrafac regulation 6118672 6118684 . . . V$BRIGHT.01:114chr10 GenomeTrafac regulation 6118673 6118687 . . . V$LHX3.01:115chr10 GenomeTrafac regulation 6118675 6118687 . . . V$BRIGHT.01:116chr10 GenomeTrafac regulation 6118676 6118688 . . . V$MSX.01:117# 65524:65581# 65492:65523# 65477:65489# 65460:65464# 65404:65435# 65389:65401# 65374:65382# 65327:65349# 65309:65326# 65292:65304# 65267:65287# 65242:65266# 65235:65241# 65216:65225# 65199:65214# 65167:65198# 65140:65156# 65100:65121# 65086:65096# 65063:65073# 65028:65052# 65023:65027# 64984:65016# 64963:64971# 64926:64962# 64843:64906# 64829:64842# 64822:64826# 64792:64807# 64777:64791# 64761:64772# 64704:64760# 64134:64139# 64109:64133# 64074:64108# 64032:64072# 63996:64031# 63962:63994chr10 GenomeTrafac regulation 6120286 6120308 . . . V$TAACC.01:118chr10 GenomeTrafac regulation 6120287 6120301 . . . V$AML3.01:119chr10 GenomeTrafac regulation 6120298 6120314 . . . V$HNF1.02:120# 63941:63958# 63925:63940# 63890:63924# 63821:63875# 63781:63819# 63758:63776# 63741:63756# 63730:63740# 63720:63725# 63699:63717# 63647:63698chr10 GenomeTrafac regulation 6120620 6120628 . . . V$MTBF.01:121# 63609:63645# 62465:62538# 62455:62463# 62432:62454# 62411:62431# 62391:62403# 62356:62371# 62307:62348# 60195:60226# 60167:60194# 60076:60155# 60064:60068# 60044:60059# 60022:60042# 59983:60019# 57137:57147# 57121:57136# 57103:57119# 57091:57102# 57053:57088# 57027:57051# 57019:57026# 56999:57017# 56992:56998# 56950:56982# 56906:56944# 56840:56905# 56818:56839# 56806:56816# 56730:56802chr10 GenomeTrafac regulation 6127491 6127507 . . . V$HNF1.01:122chr10 GenomeTrafac regulation 6127492 6127514 . . . V$TAACC.01:123chr10 GenomeTrafac regulation 6127499 6127513 . . . V$AML1.01:124chr10 GenomeTrafac regulation 6127510 6127524 . . . V$AML1.01:125chr10 GenomeTrafac regulation 6127521 6127535 . . . V$OCT1.05:126# 56714:56729# 56701:56713# 56660:56700chr10 GenomeTrafac regulation 6127586 6127604 . . . V$STAT5.01:127# 56578:56659chr10 GenomeTrafac regulation 6127648 6127670 . . . V$HMEF2.01:128chr10 GenomeTrafac regulation 6127657 6127673 . . . V$BCL6.02:129# 56542:56575chr10 GenomeTrafac regulation 6127718 6127736 . . . V$STAT5.01:130chr10 GenomeTrafac regulation 6127718 6127736 . . . V$STAT5.01:131# 56530:56541# 56517:56522# 56498:56516chr10 GenomeTrafac regulation 6127765 6127779 . . . V$CREL.01:132# 51501:51513# 51471:51500# 51438:51470# 51404:51437# 51377:51392# 51363:51371# 51348:51350# 51330:51340# 51283:51318# 51254:51281# 51217:51232# 51211:51215# 51195:51209# 51176:51193# 51148:51175# 51099:51147# 51086:51096# 51062:51076# 51041:51061# 51016:51039# 50983:51015chr10 GenomeTrafac regulation 6133264 6133278 . . . V$RREB1.01:133chr10 GenomeTrafac regulation 6133268 6133286 . . . V$STAT3.01:134chr10 GenomeTrafac regulation 6133276 6133288 . . . V$MYT1L.01:135# 50902:50981chr10 GenomeTrafac regulation 6133304 6133324 . . . V$CREBP1CJUN.01:136chr10 GenomeTrafac regulation 6133305 6133325 . . . V$CREBP1CJUN.01:137chr10 GenomeTrafac regulation 6133307 6133319 . . . V$E4F.01:138chr10 GenomeTrafac regulation 6133310 6133322 . . . V$E4F.01:139chr10 GenomeTrafac regulation 6133313 6133325 . . . V$MYT1.02:140chr10 GenomeTrafac regulation 6133331 6133349 . . . V$STAT6.01:141chr10 GenomeTrafac regulation 6133335 6133353 . . . V$ISRE.01:142chr10 GenomeTrafac regulation 6133340 6133352 . . . V$MYT1.02:143# 50881:50899# 50847:50880# 50834:50845# 50813:50824# 50774:50812# 50387:50425# 50340:50386# 50328:50339# 50318:50325# 50278:50305# 50270:50276# 50231:50261# 50211:50230# 50122:50200chr10 GenomeTrafac regulation 6134139 6134153 . . . V$NFY.03:144# 50107:50118# 50094:50106# 50066:50090# 50054:50065# 50028:50049# 49990:50026# 49943:49988# 49927:49938# 49879:49926chr10 GenomeTrafac regulation 6134368 6134378 . . . V$PIT1.01:145# 49853:49868# 49786:49848chr10 GenomeTrafac regulation 6134442 6134458 . . . V$LEF1.01:146# 49779:49785# 49745:49770# 49738:49744# 49720:49725# 49699:49709# 49684:49692# 49608:49654# 49597:49607# 49515:49596chr10 GenomeTrafac regulation 6134696 6134704 . . . V$MTBF.01:147chr10 GenomeTrafac regulation 6134748 6134762 . . . V$CREL.01:148# 49512:49514# 49465:49511chr10 GenomeTrafac regulation 6134768 6134788 . . . V$TAXCREB.02:149chr10 GenomeTrafac regulation 6134772 6134782 . . . V$AP1.02:150chr10 GenomeTrafac regulation 6134772 6134782 . . . V$AP1.01:151chr10 GenomeTrafac regulation 6134797 6134807 . . . V$NFAT.01:152# 49451:49464# 49434:49445# 49426:49433# 49420:49425# 49406:49419# 49318:49389# 48177:48192# 48171:48176# 48143:48170# 48116:48130# 48092:48111# 48033:48081# 48013:48031# 47992:48012# 47963:47988# 47954:47961# 47936:47953# 47836:47934# 47815:47834# 47572:47636# 47550:47569# 47498:47547# 47446:47497chr10 GenomeTrafac regulation 6136789 6136805 . . . V$CLOX.01:153chr10 GenomeTrafac regulation 6136789 6136801 . . . V$GATA3.02:154chr10 GenomeTrafac regulation 6136790 6136806 . . . V$CDPCR3HD.01:155chr10 GenomeTrafac regulation 6136796 6136812 . . . V$CDP.01:156chr10 GenomeTrafac regulation 6136800 6136812 . . . V$GATA3.02:157# 47276:47310# 47254:47273# 47242:47253# 47197:47240# 47184:47196# 47165:47182# 47158:47164# 47148:47154# 47141:47145# 47110:47138# 47079:47100# 47019:47036# 46923:47018# 46907:46922# 46895:46906# 46267:46360# 46257:46266# 46193:46256# 46147:46192# 46131:46146# 46087:46130# 46079:46085# 46012:46064chr10 GenomeTrafac regulation 6138253 6138265 . . . V$PAX8.01:158chr10 GenomeTrafac regulation 6138254 6138264 . . . V$PIT1.01:159# 45994:46011# 45967:45993# 45841:45888chr10 GenomeTrafac regulation 6138393 6138405 . . . V$MYT1.02:160# 45060:45076# 45039:45058# 45025:45037# 45016:45023# 45001:45015# 44987:45000# 44972:44986# 44920:44971# 44887:44919chr10 GenomeTrafac regulation 6139372 6139386 . . . V$RBPJK.02:161chr10 GenomeTrafac regulation 6139373 6139385 . . . V$IK2.01:162chr10 GenomeTrafac regulation 6139376 6139388 . . . V$MYT1.02:163# 44852:44886# 44778:44851# 44737:44777# 44715:44736# 44651:44714# 44633:44650# 44551:44630# 44476:44542# 44468:44475# 44063:44092# 44017:44062# 43977:43992# 43954:43975# 43926:43952# 43909:43921# 43892:43902# 43847:43891# 43823:43845# 43790:43822# 43765:43782# 43754:43763# 43632:43733chr10 GenomeTrafac regulation 6140612 6140624 . . . V$GATA1.02:164# 43607:43620# 43571:43606chr10 GenomeTrafac regulation 6140687 6140705 . . . V$STAT.01:165chr10 GenomeTrafac regulation 6140687 6140705 . . . V$STAT5.01:166chr10 GenomeTrafac regulation 6140688 6140700 . . . V$IK3.01:167chr10 GenomeTrafac regulation 6140689 6140705 . . . V$BCL6.01:168# 43553:43566# 43499:43545chr10 GenomeTrafac regulation 6140744 6140762 . . . V$STAT5.01:169chr10 GenomeTrafac regulation 6140744 6140762 . . . V$STAT5.01:170# 43483:43498# 43471:43482# 43408:43469chr10 GenomeTrafac regulation 6140834 6140856 . . . V$MMEF2.01:171chr10 GenomeTrafac regulation 6140855 6140865 . . . V$AP1.02:172# 43349:43407chr10 GenomeTrafac regulation 6140883 6140899 . . . V$BRN2.01:173chr10 GenomeTrafac regulation 6140897 6140911 . . . V$CEBPB.01:174chr10 GenomeTrafac regulation 6140899 6140913 . . . V$OCT1.06:175chr10 GenomeTrafac regulation 6140900 6140916 . . . V$HMGIY.01:176chr10 GenomeTrafac regulation 6140901 6140917 . . . V$HMGIY.01:177chr10 GenomeTrafac regulation 6140904 6140918 . . . V$OCT1.06:178chr10 GenomeTrafac regulation 6140914 6140928 . . . V$OCT1.05:179# 43310:43347chr10 GenomeTrafac regulation 6140932 6140942 . . . V$AP1.01:180chr10 GenomeTrafac regulation 6140951 6140967 . . . V$XFD3.01:181chr10 GenomeTrafac regulation 6140958 6140966 . . . V$MEIS1.01:182# 43290:43309# 43261:43289# 43240:43258# 43195:43239# 43173:43193# 43148:43164# 43126:43146# 43047:43100# 43018:43036# 43003:43014# 42968:42990# 42938:42957# 42895:42931# 42872:42892# 42832:42871chr10 GenomeTrafac regulation 6141418 6141434 . . . V$TATA.01:183chr10 GenomeTrafac regulation 6141425 6141441 . . . V$TATA.01:184# 42792:42831# 42783:42791# 42777:42782# 42765:42776# 42749:42764# 42726:42748# 42712:42725# 42692:42707# 42672:42691# 42658:42669# 42642:42650# 42631:42637# 42586:42622# 42562:42583# 42538:42561chr10 GenomeTrafac regulation 6141718 6141732 . . . V$OCT1.06:185chr10 GenomeTrafac regulation 6141719 6141735 . . . V$HMGIY.01:186chr10 GenomeTrafac regulation 6141720 6141736 . . . V$HMGIY.01:187# 42491:42536# 42464:42471# 42433:42451# 42409:42419# 42403:42406# 42394:42397# 42368:42384# 42338:42349# 42326:42337# 42264:42278# 42237:42263# 42164:42233chr10 GenomeTrafac regulation 6142049 6142065 . . . V$EN1.01:188# 42133:42162# 42129:42132# 42094:42128chr10 GenomeTrafac regulation 6142152 6142166 . . . V$GFI1B.01:189# 41332:41349# 41324:41331# 41296:41320# 41230:41294chr10 GenomeTrafac regulation 6143010 6143018 . . . V$S8.01:190# 41214:41229# 40436:40446# 40429:40435# 40261:40428chr10 GenomeTrafac regulation 6143855 6143863 . . . V$MTBF.01:191chr10 GenomeTrafac regulation 6143933 6143955 . . . V$STAF.01:192chr10 GenomeTrafac regulation 6143943 6143957 . . . V$BTEB3.01:193# 40228:40260# 40138:40227chr10 GenomeTrafac regulation 6144114 6144130 . . . V$ELF2.01:194# 40095:40137# 40064:40088# 40017:40063# 39952:40014chr10 GenomeTrafac regulation 6144295 6144311 . . . V$ATATA.01:195# 39942:39950# 39938:39941# 39917:39934# 39889:39914chr10 GenomeTrafac regulation 6144368 6144384 . . . V$HNF3B.01:196# 39848:39881chr10 GenomeTrafac regulation 6144400 6144416 . . . V$CDPCR3.01:197chr10 GenomeTrafac regulation 6144410 6144426 . . . V$HMGIY.01:198chr10 GenomeTrafac regulation 6144414 6144424 . . . V$PAX4.01:199chr10 GenomeTrafac regulation 6144418 6144430 . . . V$CHR.01:200# 39822:39846chr10 GenomeTrafac regulation 6144441 6144453 . . . V$MYT1.01:201chr10 GenomeTrafac regulation 6144442 6144452 . . . V$PXRCAR.01:202# 39735:39821chr10 GenomeTrafac regulation 6144525 6144539 . . . V$GKLF.01:203# 39659:39733chr10 GenomeTrafac regulation 6144555 6144567 . . . V$EKLF.01:204chr10 GenomeTrafac regulation 6144556 6144570 . . . V$SREBP.02:205chr10 GenomeTrafac regulation 6144577 6144595 . . . V$NF1.01:206# 36710:36729# 36685:36709# 36668:36684# 36654:36666# 36627:36651# 36573:36619chr10 GenomeTrafac regulation 6147664 6147678 . . . V$DBP.01:207# 36552:36570# 36539:36551# 36516:36538# 36426:36514chr10 GenomeTrafac regulation 6147770 6147782 . . . V$CHR.01:208chr10 GenomeTrafac regulation 6147775 6147787 . . . V$MYT1.02:209chr10 GenomeTrafac regulation 6147783 6147795 . . . V$CHR.01:210chr10 GenomeTrafac regulation 6147807 6147825 . . . V$STAT.01:211chr10 GenomeTrafac regulation 6147823 6147835 . . . V$CHR.01:212# 36394:36406# 36365:36393# 36316:36342# 36305:36315# 36284:36304# 36270:36283# 36160:36268chr10 GenomeTrafac regulation 6148016 6148030 . . . V$CEBPB.01:213chr10 GenomeTrafac regulation 6148027 6148045 . . . V$STAT5.01:214chr10 GenomeTrafac regulation 6148028 6148040 . . . V$GATA1.03:215chr10 GenomeTrafac regulation 6148047 6148065 . . . V$STAT5.01:216chr10 GenomeTrafac regulation 6148047 6148065 . . . V$STAT5.01:217# 36121:36159# 36107:36120# 36042:36106# 35948:36041chr10 GenomeTrafac regulation 6148239 6148251 . . . V$SF1.01:218# 35892:35947# 35844:35878# 34442:34502# 34410:34429# 34394:34409# 34390:34445# 34372:34389# 34360:34371# 34355:34379chr10 GenomeTrafac regulation 6149913 6149921 . . . V$MTBF.01:219# 34347:34356# 34312:34345# 34264:34311# 34251:34262# 34231:34249# 34197:34230# 33891:33958chr10 GenomeTrafac regulation 6150337 6150353 . . . V$LEF1.02:220# 33858:33890# 33827:33851# 33754:33816# 33722:33746# 33707:33720# 33671:33706# 33657:33668# 33607:33653# 33575:33630chr10 GenomeTrafac regulation 6150676 6150692 . . . V$LEF1.01:221# 33555:33561# 33518:33553# 33494:33515# 33477:33490# 33468:33472# 33435:33460# 33383:33433# 33350:33368# 33315:33349# 33305:33313# 33265:33301# 33235:33246# 33228:33232# 33205:33227# 33196:33203# 33163:33193# 33136:33155# 33127:33135# 33094:33126# 33049:33092# 32915:33048chr10 GenomeTrafac regulation 6151248 6151266 . . . V$NF1.01:222chr10 GenomeTrafac regulation 6151305 6151317 . . . V$MSX2.01:223chr10 GenomeTrafac regulation 6151306 6151324 . . . V$STAT5.01:224chr10 GenomeTrafac regulation 6151306 6151324 . . . V$STAT5.01:225chr10 GenomeTrafac regulation 6151315 6151329 . . . V$FAST1.01:226chr10 GenomeTrafac regulation 6151320 6151334 . . . V$PLZF.01:227chr10 GenomeTrafac regulation 6151322 6151334 . . . V$AREB6.03:228chr10 GenomeTrafac regulation 6151325 6151343 . . . V$ARE.01:229chr10 GenomeTrafac regulation 6151325 6151341 . . . V$CETS1P54.01:230# 32881:32913# 32801:32871chr10 GenomeTrafac regulation 6151413 6151423 . . . V$NFAT.01:231# 32797:32800# 32756:32794# 32751:32755# 32722:32746# 32685:32719# 32662:32683# 32527:32582# 32501:32526# 32466:32499# 32455:32462# 32436:32452# 32391:32435chr10 GenomeTrafac regulation 6151874 6151882 . . . V$SMAD4.01:232chr10 GenomeTrafac regulation 6151875 6151883 . . . V$SMAD4.01:233# 32356:32390# 32334:32352# 31647:31679# 31625:31644# 31601:31621# 31538:31599# 31479:31537# 31426:31477# 31382:31417# 31324:31379# 31309:31323# 31258:31306# 31248:31257# 31196:31247# 31146:31180# 29895:29920# 29873:29894# 29819:29872# 29772:29818# 29756:29770# 29736:29751# 29709:29727# 29665:29676# 29651:29664# 29618:29645# 29588:29617chr10 GenomeTrafac regulation 6154672 6154690 . . . V$STAT5.01:234# 29525:29586chr10 GenomeTrafac regulation 6154700 6154712 . . . V$PBX1.01:235# 29497:29523chr10 GenomeTrafac regulation 6154755 6154773 . . . V$STAT5.01:236chr10 GenomeTrafac regulation 6154755 6154773 . . . V$STAT5.01:237# 29480:29496# 29444:29477# 29429:29441# 29414:29427# 29381:29402# 29353:29377# 29325:29352# 29308:29362# 28021:28029# 27956:28015# 27932:27955# 27915:27930# 27865:27914# 27832:27860# 27820:27829# 27815:27819# 27751:27813chr10 GenomeTrafac regulation 6156506 6156522 . . . V$ELK1.01:238# 27729:27740# 27683:27723# 27186:27207# 27152:27185# 27120:27144# 27115:27119# 27092:27113# 27071:27091# 26055:26105# 26028:26053# 26018:26027# 25987:26017# 25964:25986# 25939:26017# 23879:23920# 23857:23878# 23755:23856# 23739:23754# 23734:23738# 23705:23730# 23690:23701# 23677:23684# 23647:23664# 23578:23646# 19027:19069# 19020:19025# 19012:19019# 18997:19011# 18962:18984# 18855:18956chr10 GenomeTrafac regulation 6165322 6165332 . . . V$VBP.01:239chr10 GenomeTrafac regulation 6165323 6165337 . . . V$OCT1.04:240# 18816:18854# 18791:18815# 18777:18789# 18751:18773# 18701:18750# 18660:18699# 18628:18632# 18561:18601# 18513:18549# 18457:18508# 18448:18456# 18388:18446chr10 GenomeTrafac regulation 6165835 6165851 . . . V$PTX1.01:241chr10 GenomeTrafac regulation 6165836 6165852 . . . V$HNF1.03:242chr10 GenomeTrafac regulation 6165864 6165876 . . . V$GATA1.03:243# 18373:18387# 18349:18370# 18300:18348# 18279:18287# 18254:18276# 18202:18252# 18172:18199# 18149:18170# 18134:18146# 18123:18132# 18107:18115# 18081:18105# 18065:18078# 17892:17930# 17866:17890# 17829:17858# 17751:17826# 16888:16923chr10 GenomeTrafac regulation 6167373 6167385 . . . V$MYT1.02:244# 16841:16885# 16814:16839# 16804:16813# 16722:16803# 16708:16721# 16688:16706# 16655:16678# 16634:16648# 16625:16632# 16612:16624# 16556:16610# 16515:16555# 16506:16514# 16398:16419# 16371:16396# 16334:16361# 16321:16333# 16289:16320# 16267:16279# 16267:16341# 16237:16265# 16237:16265# 16202:16227# 16198:16221# 16184:16194# 16171:16183# 16171:16197# 16138:16169# 16121:16169# 14553:14617chr10 GenomeTrafac regulation 6169663 6169675 . . . V$DLX3.01:245chr10 GenomeTrafac regulation 6169674 6169688 . . . V$FAST1.01:246chr10 GenomeTrafac regulation 6169707 6169717 . . . V$PIT1.01:247# 14534:14552# 14505:14521# 14497:14503# 14474:14486# 14449:14461# 14432:14440# 14417:14427# 14398:14415# 14375:14397# 14348:14373# 14341:14347# 13821:13848# 13769:13818# 13742:13764# 13732:13741# 13710:13730# 13697:13709# 13679:13695# 13649:13659# 13626:13643chr10 GenomeTrafac regulation 6170639 6170651 . . . V$RP58.01:248# 13573:13623chr10 GenomeTrafac regulation 6170672 6170688 . . . V$TATA.01:249# 13555:13561# 13520:13537# 13501:13509# 13482:13498# 13439:13460# 13425:13438# 13397:13411# 13359:13395# 13330:13340# 13321:13324# 13094:13320chr10 GenomeTrafac regulation 6170968 6170982 . . . V$HES1.01:250chr10 GenomeTrafac regulation 6170984 6170996 . . . V$CDE.01:251chr10 GenomeTrafac regulation 6171001 6171013 . . . V$CDE.01:252chr10 GenomeTrafac regulation 6171016 6171028 . . . V$CDE.01:253chr10 GenomeTrafac regulation 6171078 6171090 . . . V$AP2.01:254chr10 GenomeTrafac regulation 6171090 6171108 . . . V$MUSCLE_INI.01:255chr10 GenomeTrafac regulation 6171092 6171106 . . . V$HES1.01:256chr10 GenomeTrafac regulation 6171147 6171161 . . . V$SP1.01:257chr10 GenomeTrafac regulation 6171160 6171172 . . . V$NKX32.01:258# 13079:13092# 13073:13078# 13052:13072chr10 GenomeTrafac regulation 6171211 6171221 . . . V$ZF5.01:259chr10 GenomeTrafac regulation 6171213 6171223 . . . V$ZF5.01:260# 13017:13050# 13006:13016# 12974:13005# 12960:12973# 12947:12959# 12907:12930# 12898:12904track name="Enhancers" description="Enhancers on this gene" color=255,20,147 visibility=4 priority=7useScore=0chr10 GenomeTrafac enhancer 6144341 6144416 . . . "Positive RegulatoryRegion II"chr10 GenomeTrafac enhancer 6144523 6144555 . . . "Positive RegulatoryRegion I"chr10 GenomeTrafac enhancer 6147993 6148070 . . . "Positive RegulatoryRegion III"


AAAAAAAAAAAAAAAAAAA (simple repeat)

Hs-MmConservedBinding Sites

Gen

omeT

rafa

c: IL2RA

GFF

Gen

omeT

rafa

c: IL2RA

GFF

Known enhancers

BlastZ Alignment


Tasks• Parsing all GenBank files that have regulatory

information explicitly stated (as in the “Features” E.g.enhancer – 1045 sequences). Extract the sequences andmap them to GenomeTrafac and UCSC.

• Text-parsing “regulatory-rich” abstracts – Identify set ofkeywords.

• Associating nucleotide sequences to the “regulatory-rich” abstracts.

• Incorporating the noncoding SNPs and knownregulatory region info into the GenomeTrafac GFFexport files.

Documents

Detection and visualization of conserved cis · 2012-05-02 · NesPlacZ/3 and E/nestin:EGFP mice showed reporter gene expression in stem cell-containing regions of brain and spinal