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Dermatopathology Slide Review Part 152 Paul K. Shitabata, M.D. Dermatopathology Institute Torrance, CA Wednesday, November 23, 11

Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

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Page 1: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Dermatopathology Slide Review Part 152

Paul K. Shitabata, M.D.Dermatopathology Institute

Torrance, CA

Wednesday, November 23, 11

Page 2: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 3: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 4: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 5: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 6: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

CK 20

Wednesday, November 23, 11

Page 7: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Synaptophysin

Wednesday, November 23, 11

Page 8: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Merkel Cell Carcinoma

Wednesday, November 23, 11

Page 9: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Hyperchromatic cells with nuclear molding and

stippled nuclear chromatin

Paranuclear Dot-like positivity

with Cytokeratin stains

Wednesday, November 23, 11

Page 10: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 11: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 12: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 13: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 14: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Dermatofibroma with Sclerosing

Hemangioma Features

Wednesday, November 23, 11

Page 15: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Spindle cells with Touton-type Giant Cells

Hemorrhage and hemosiderin macrophages

Spindle Cells Entrapping Collagen

Wednesday, November 23, 11

Page 16: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 17: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 18: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 19: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 20: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Verruca Plana

Wednesday, November 23, 11

Page 21: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Superficial Koilocytes

Minimal Cytologic Atypia

Minimal to absent Papillomatosis

Wednesday, November 23, 11

Page 22: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 23: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 24: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 25: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 26: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Leukocytoclastic Vasculitis

Wednesday, November 23, 11

Page 27: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Must have Fibrinoid Necrosis

Extravasated rbcs

Nuclear Dust

Wednesday, November 23, 11

Page 28: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 29: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 30: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 31: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Wednesday, November 23, 11

Page 32: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Sebaceous Adenoma

Wednesday, November 23, 11

Page 33: Dermatopathology Slide Review Part 152 - DermpathMD.com · Hyperchromatic cells with nuclear molding and stippled nuclear chromatin Paranuclear Dot-like positivity with Cytokeratin

Circumscribed lobules of mature sebaceous lobules

Basal layer surrounding sebocytes

Minimal Atypia

Wednesday, November 23, 11

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