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Colleagues, As Evans Days approaches, I hope each of you find pride in the extraordinary accomplishments of our faculty, many of which are highlighted in this edion of the electronic newsleer. I would parcularly like to congratulate Maureen Debreuil, M.D. and Melissa Farb, Ph.D. on their selecon as the AY 2018/19 Evans Junior Faculty Research Merit Awardees. The compeon for this honor was the sffest in recent memory. Later this week at our Evans Days dinner, we will also be celebrang the selecon of Evans Clinicians and a number of research, cizenship, and mentoring awards for our faculty and trainees. Over the next few months, we will be interviewing intern candidates for our residency program and preparing with BMC for Medicaid payment reform through the Boston Accountable Care Organizaon. Our success in these endeavors will posion our department for a very bright future! I hope you enjoy this edion of the newsleer and look forward to seeing you at Evans Days! David Coleman, M.D. Message from the Chairman Boston Medical Center/ Boston University School of Medicine Department of Medicine Newsletter Fall 2017 Department of Medicine Newsletter

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Page 1: Department of Medicine Newsletter · Department of Medicine Newsletter Page 4 We are delighted and proud to announce that the following students from the oston University School of

Colleagues, As Evans Days approaches, I hope each of you find pride in the extraordinary accomplishments of our faculty, many of which are highlighted in this edition of the electronic newsletter. I would particularly like to congratulate Maureen Debreuil, M.D. and Melissa Farb, Ph.D. on their selection as the AY 2018/19 Evans Junior Faculty Research Merit Awardees. The competition for this honor was the stiffest in recent memory. Later this week at our Evans Days dinner, we will also be celebrating the selection of Evans Clinicians and a number of research, citizenship, and mentoring awards for our faculty and trainees. Over the next few months, we will be interviewing intern candidates for our residency program and preparing with BMC for Medicaid payment reform through the Boston Accountable Care Organization. Our success in these endeavors will position our department for a very bright future! I hope you enjoy this edition of the newsletter and look forward to seeing you at Evans Days! David Coleman, M.D.

Message from the Chairman

Boston Medical Center/ Boston University School of Medicine

Department of Medicine

Newsletter

Fall 2017 Department of Medicine Newsletter

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Congratulations To All Award Recipients!

Page 2

The Women’s Health Group in GIM was awarded a UO1 grant to address cancer health disparities in Boston.

A collaborative grant from NCATs that will be led by Tracy Battaglia, MD, MPH at BMC, in collaboration with the 4 MA

CTSA programs (BU, TUFTs, Harvard and UMass)

Dr. Ian Rifkin has been awarded a $2.5 million grant from NIH over 5 years to study the pathogenesis of systemic

lupus erythematosus

Dr. Vipul Chitalia promoted to Associate Professor of Medicine

Dr. Weining Lu's collaboration with Pfizer CTI on the

development of Robo2-Fc for the treatment of proteinuric kidney diseases has entered phase 1 clinical trials

Dr. Laurence Beck and post-doctoral fellow Claire Avillach, in collaboration with a national group of investigators, have

discovered that megalin is the target antigen in a previously poorly recognized form of autoimmune kidney

disease. This work has been accepted for publication in the Journal of the American Society of Nephrology

Department of Medicine Newsletter

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Congratulations To All Award Recipients!

Page 3

Dr. James Hudspeth to receive the 2017 Excellence in Care Award

The Excellence in Care Award recognizes FPF members who have demonstrated clinical excellence and who are

exceptional role models for core FPF values in their clinical work. James were selected from a truly outstanding group

of nominees representing the best clinicians and clinical leaders from across the institution

James will also be inducted into the FPF Clinical Excellence Society. The Society was formed to recognize the highest

level of clinical excellence. This year 15 inaugural members were chosen to be a part of the society

The first Annual FPF Recognition Ceremony will take place on Wednesday, October 18, 2017 from 5:00 – 7:30 pm in

Hiebert Lounge on the 14th floor of BUSM

Dr. Jeffrey Samet received the American College of Physicians’ First Richard and Hinda Rosenthal Award from

The Rosenthal Family Foundation in recognition of his notable contributions to improve clinical care in the field of

internal medicine

Department of Medicine Newsletter

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Department of Medicine Newsletter

Page 4

We are delighted and proud to announce that the following students from the Boston University School of Medicine Class of 2018 have been elected to membership in Alpha Omega Alpha.

Alpha Omega Alpha (AOA) is the only national honor medical society, and it is organized exclusively for educational purposes. Its aims are the promotion of scholarship and research in medical schools, the encouragement of high standards of character and conduct among medical students and graduates, and the recognition of high attainment in medical sciences, practice, and related fields. Its motto is: "Be worthy to serve the suffering."

Kevin Arndt

Katelin Blackburn

Nishant

Dwivedi

Karina Esquenazi

Yi Feng

Joseph Hodgkin

Terry Hsieh

Pamela Huang

Aaron Kaufman

Orly Leiva

Gareth Marshall

Ryan Morgan

Tara Neary

Angela Nolin

Nicholas Pagani

Matthew Peacock

Michal Plocienniczak

Ariel Porto

Antoine Ribieras

Sean Schowalter

Aditya Sengupta

Nishant Shah

James Trussler

Natalie Tukan

Brian Williams

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CReM Honored for Sharing Stem Cell Lines

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Darrell Kotton, Gustavo Mostoslavsky, and George Murphy began the Center for Regenerative Medicine (CReM) in 2008 with a mission. It was not to win a Nobel Prize, launch more spin-offs than their peers, or make megabucks and retire at 35. Rather, their mantra was both humbler and grander: “decrease the burden of human suffering on the planet, help patients, and advance new knowledge.”

Since then, the lab has made a name for itself not only through its top-notch research on stem cells and lung disease but also because of its willingness to share the resources they create—for free, to anyone.

CReM’s philosophy of openness challenges the cutthroat, hypersecret culture that dominates many other life science labs. And now the lab’s commitment to open-source biology, as it is known, has earned it the 2017 Sharing Research Resources Award from the Association of American Medical Colleges (AAMC), established “to recognize successful models for sharing biomedical research resources.”

CReM’s sharing of unpublished stem cell lines has broadly impacted the lung research community, resulting in collaborations and publications with groups formerly considered CReM competitors, and CReM recently became sole iPSC repository for the 7,000 participants of the long-running Framingham Heart Study, the nation’s longest running epidemiological study, which began in 1948 and has been run by BU since 1971, with support from the National Heart, Lung, and Blood Institute.

Kotton says that the award acknowledges not only the work of CReM, but of all the other labs and institutions that have joined in this venture into scientific sharing. “Just the fact that an award like this exists,” he says, “shows that this way of doing research has value.”

Department of Medicine Newsletter

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Name: Nellie Ferrara Job title: Senior Administrative Coordinator Location: Evans 113 How many years have you been at BMC? 6 years What do you like best about your job? The people! I’ve had the privilege of working with some pretty amazing people throughout the department. I’ve made some incredible friends both on a personal level and professional level. What do you like least about your job? Between the heavy foot traffic through our suite literally all day long and the phone calls both from colleagues within our department and outside our department, it is very easy to get distracted and forget what you’re doing. What do you wish more people knew about your job? That I do a lot more than what meets the eye. I kind of get introduced to new people as “The Girl Who Knows Everything”, so I get a lot of people asking me to help them with things whether it be an IT question (that’s why I changed my last name so my initials wouldn’t be I.T anymore), a reporting question, a general DOM question, or a question about what’s going on with one of our Boston sports teams. Favorite lunch spot? El Centro. I usually have a little extra pep in my step and sing a little tune if I know I’m having lunch there. Favorite thing to do outside of work? My friends will hate me if I don’t say “Spend time with friends” but everybody knows me well enough when I say that I absolutely love to play and watch sports. I’ve been playing ice hockey since I was about 10 years old and just recently had to stop playing in a co-ed league due to my concussion history. I’m also in a bowling league. I’m not that great but I can beat the sweet 80 year old lady that’s in my league so that’s all that matters. Fun Fact: I coach 4 & 5 year olds in ice hockey. Before the start of each practice season, I have each of them tell me who their favorite hockey player is and that’s what I call them every practice. It’s so much fun to see their huge smiles when you call them “Patrice Bergeron” or “Bobby Orr” while they try to skate with a puck. We’re still working on that hand/eye coordination thing though.

DOM Unsung Hero: Nellie Ferrara

Department of Medicine Newsletter

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The Department of Medicine Education Evaluation

Core: Brief Overview The purpose of the Education Evaluation Core (EEC) is to provide

research support to clinician educators within the Department of

Medicine (DOM). The EEC provides consultation on a wide range

of research tasks:

Articulating hypotheses and research questions

Developing logic models and theories of change

Designing studies

Creating original data collection instruments

Analyzing data

Identifying appropriate outlets for scholarship

Preparing manuscripts for submission

Identifying opportunities and applying for external

funding

If you are a clinician educator in the DOM and would like support

with any anticipated or ongoing research activities, please email

the director of the Core, Dr. Lindsay Demers at

[email protected] to schedule an appointment.

Did You Know?

Department of Medicine Newsletter

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Fall Spotlight: Evans Center for Implementation and Improvement Sciences (CIIS)

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Translating evidence-based practices from research into clinical practice takes on average 17 years, and many of these practices are never adopted for routine use. Failure to bring evidence-based practices such as routine risk screenings for substance use or Hepatitis C, and guidelines on medication prescribing into clinical usage promotes gaps in care quality and access. These gaps can disproportionately affect the health of vulnerable populations including the uninsured, underinsured and Medicaid beneficiaries that seek care from Boston Medical Center (BMC).

In 2015, the Department of Medicine established the Evans Center for Implementation and Improvement Sciences (CIIS) to investigate strategies that increase the evidence uptake into clinical practice for safety net populations. CIIS serves as Boston University’s methodological hub for the scientific evaluation of efforts to improve healthcare delivery by focusing on two critical scientific approaches: implementation and improvement. Dr. Mari-Lynn Drainoni and Dr. Allan Walkey co-direct the Center. Erika Crable serves as Research Fellow and Dea Biancarelli is a Research Assistant at CIIS.

CIIS Research and Objectives

As a locus of implementation

science, CIIS systematically studies

the processes and factors that

influence a health system’s ability to

adopt and sustain evidence-based

practices in real world settings. Our

implementation research focuses on

identifying optimal strategies that

enable stakeholders to carry out

delivery systems changes within the confines of daily workflow. For example, CIIS is currently

funding research led by Boston University School of Medicine faculty to analyze a Best

Practice Alert prompting BMC providers to conduct smoking cessation consultations for all

admitted smokers. Some of the key outcomes will include provider satisfaction with the Best

Practice Alert and consult order, the time and cost associated with providing this service,

including any barriers or enabling workflow factors that affect providers’ compliance.

Department of Medicine Newsletter

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Through our improvement science research, CIIS is focusing on designing methods that rigorously measure outcomes associated with efforts to improve healthcare delivery. The improvement science approach enables researchers to identify which of their studied efforts resulted in positive health outcomes for a local setting like BMC, and allows that knowledge to be transferred to other settings using the same rigorous methods. For example, CIIS is currently researching how to use regression discontinuity design as an evaluation strategy to evaluate efforts to reduce hospital readmission rates at BMC. The methodology is being applied to leverage interventions performed at different levels of readmissions risk as predicted by risk scores that model patients’ probability of experiencing a 3-month readmission.

Spreading Knowledge Throughout the BU Community Supporting and training the Boston University community in implementation and

improvement sciences is a significant part of CIIS’s mission. CIIS annually funds pilot studies that use implementation science strategies to increase use of evidence based- or compelling evidence-informed practices into routine clinical use. We are in our second year of pilot funding and look forward to sharing updates from our year one and two studies soon!

CIIS is also available to provide direct technical assistance to investigators conceptualizing,

designing and conducting implementation studies. Beyond the core CIIS team, we have developed a network of CIIS affiliates including researchers from Boston University School of Medicine and School of Public Health, as well as the Veterans Administration. CIIS affiliates expand our technical assistance reach, offering additional expertise in diverse disciplines including anthropology, econometrics, emergency medicine, and quality improvement, amongst others. CIIS affiliates regularly join us for seminars open to the Boston University community.

Fall Spotlight: Evans Center for Implementation and Improvement Sciences (CIIS)

Department of Medicine Newsletter

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CIIS is also beginning a new monthly skill-based educational series open to the Boston University Medical Campus community. This new initiative, Transforming Implementation and Improvement Into Science: A Skills Building Series, will focus on developing skills for writing successful implementation and improvement sciences grant applications for submission to CIIS for pilot funding, or to other grant makers. The first Transforming Implementation and Improvement Into Science session will be on October 25, 2017.

You can follow CIIS’s work and upcoming events by:

Visiting our website: http://sites.bu.edu/ciis/ Following us on Twitter: @EvansCIIS Emailing us: [email protected]

Fall Spotlight: Evans Center for Implementation and Improvement Sciences (CIIS)

Department of Medicine Newsletter

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EVANS DEPARTMENT OF MEDICINE RESEARCH DAYS

October 12 – 13, 2017

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We are pleased to announce the 2017 Wilkins and

Ingelfinger Visiting Professors

Wilkins Visiting Professor Ingelfinger Visiting Professor

Dr. Nancy J. Cox, PhD Dr. Katrina Armstrong, MD

Mary Phillips Edmonds Gray Chair Physician-in-Chief

Professor of Medicine Massachusetts General Hospital

Vanderbilt University Medical Center Harvard Medical School

Department of Medicine Newsletter

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Schedule of Events: Thursday, October 12, 2017 Research Poster Session 9:00 – 12 noon, Hiebert Lounge Wilkins Visiting Professor Lecture 3:30 pm, Keefer Auditorium Evans Days Gala - 2017 Awards Dinner 6:00 pm, Colonnade Hotel Friday, October 13, 2017 Ingelfinger Visiting Professor – GRAND Rounds 12:00 noon, Keefer Auditorium

EVANS DEPARTMENT OF MEDICINE RESEARCH DAYS

October 12 – 13, 2017

Department of Medicine Newsletter

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Faculty Development Seminars

How to Design a Curriculum

Priya Garg

October 3rd from 12-1pm in Wilkins

Negotiation Skills for Women

Kelly Gushue

October 11th from 3-5pm in Wilkins

ICU Federation: How To Gain Institutional Control of Critical Care Quality

Part of the BMC Patient Quality and Safety Week Series: James Murphy

October 19th from 12-1 PM

Responding to Microagressions as a Bystander

Kermit Crawford

November 7th from 12-1pm in Wilkins

What to Think about When You are Thinking of Retiring

BU & BMC HR

November 15th from 3-5pm in Wilkins

CV Boot Camp

Emelia Benjamin & David Salant

December 5th from 12-1pm in Wilkins

Announcements

Department of Medicine Newsletter

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Quarterly Application Deadlines for Faculty Development Grants

ALL faculty members in the Department of Medicine are invited to apply for Faculty

Development Grants

October 9, 2017

January 15, 2018

April 15, 2018

July 15, 2018

Announcements

Department of Medicine Newsletter

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Faculty Dinner Dates

The 2017-2018 dinners are:

•Women Faculty & Trainees: November 28th, 2017

•Under-Represented Minorities & Allies Faculty & Trainees:

November 9th, 2017

•Educators: January 10th, 2018

•Women: May 2nd, 2018

•Under-Represented Minorities & Allies: May 15th, 2018

•Investigators: June 19th, 2018

Announcements

Department of Medicine Newsletter