Degree Charter - Hogeschool van Arnhem en Nijmegen · 2017-12-06 · Degree Charter For the Bachelor of Life Sciences Degree Programme ... Graphs and trendlines ... MAC-value, LD50-value,

Degree Charter

For the Bachelor of Life Sciences Degree Programme at the HAN University of Applied Sciences

2017-2018 Academic year

Chapter 2: Course Units and Integral Assessments of the Foundation Year

Institute of Applied BioSciences and Chemistry Degree Charter Part 3: Biology and Medical Laboratory Research; Life Sciences Description of the education 2017-2018 Chapter 2: Course Units and Integral Assessments of the Foundation Year

2

Contents

Course unit 1: Basic knowledge for Life Sciences ............................................................................................................... 3

Assessment programme course unit 1: Basic knowledge for Life Sciences (LS1) ............................................................ 6

Course unit 2a: Basic practical skills Chemistry, Biology & Medical ................................................................................ 13

Assessment programme course unit 2a: Basic practical skills Chemistry, Biology & Medical (LS2a) ............................ 15

Course unit 2b: Basic theory Biology and Medical ........................................................................................................... 25

Assessment programme course unit 2b: Basic theory Biology and Medical (LS2b) ...................................................... 27

Course unit 2c: Basic Theory Chemistry............................................................................................................................ 31

Assessment programme course unit 2c: Basic theory Chemistry (LS2c) ........................................................................ 33

Course unit LS3K: Knowledge of molecular biology and biochemical research of DNA and protein ........................... 37

Assessment programme course unit LS3K: Knowledge of molecular biology and biochemical research of DNA and protein (LS3K) ..................................................................................................................................................................... 39

Course unit LS3P: Practical molecular biology and biochemical research on DNA and protein ................................... 42

Assessment programme course unit LS3P: Practical molecular biology and biochemical research on DNA and protein (LS3P) ..................................................................................................................................................................... 44

Course unit LS3T: Molecular biology and biochemical research of DNA and protein ................................................... 48

Assessment programme course unit LS3T: Molecular biology and biochemical research of DNA and protein (LS3T) ............................................................................................................................................................................................. 50

Course unit LS4K: Knowledge about medical diagnostics ............................................................................................... 54

Assessment programme course unit LS4K: Knowledge about medical diagnostics (LS4K) ........................................... 56

Course unit LS4P: Practical medical Diagnostics .............................................................................................................. 57

Assessment programme course unit LS4P: Practical medical Diagnostics (LS4P) .......................................................... 59

Course unit LS4T: Medical diagnostics .............................................................................................................................. 67

Assessment programme course unit LS4T: Medical diagnostics (LS4T) ......................................................................... 69

Course unit AB4: Introduction to cutting edge techniques in the Life Sciences ............................................................. 83

Assessment programme course unit AB4: Introduction to cutting edge techniques in the Life Sciences (AB4) ......... 86

Integral Assessment Foundation Year ............................................................................................................................106


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Course unit title Course unit 1: Basic knowledge for Life Sciences ECU 1: Basic knowledge for Life Sciences

Code LS1

1. Degree Biology and Medical Laboratory Research, Life Science/Chemistry

2. Target group

Full-time students common foundation year - Biology and Medical Laboratory

Research, Life Sciences, Chemistry

3. Professional task/

professional tasks

Carrying out life science research

4. Central

professional task

Not applicable.

5. (Professional)

Products

Not applicable.

6. Study credits,

study load

7.5 stp

210 SBU

7. Cohesion with

other course units

Course 1 is the first course of the degree programme. In this course is basic

knowledge learned or brought to the required level.

8. Entry

requirements

regarding

(interim) exams

HAVO (higher general continued education)/VWO (pre-university) diploma with

the profile Nature and Technology or Nature and Health,

MBO diploma level 4

Participation in the Workshop Interview techniques and feedback is compulsory.

9. General

description

In Course unit 1, subjects introduced are essential to the degree programme. The

basic knowledge on lab calculations, mathematics and safety is the central focus

of this course unit. Additionally, students are introduced to the Biobased

Economy and the role that chemistry and life sciences can play in it.

10. Competences - Quality control

- Teamwork

- Guiding professional development

11. Assessment

criteria

See assessment programme for description of exams, assessment criteria and

indicators.

12. Assessment Modular examinations LS1-Kvei Theory exam Safety

LS1-Klab Theory exam lab calculations

(Klab1 and Klab2)

LS1-Kwis Theoretical exam mathematics

(Kwis1 and Kwis2)

LS1-Gsp LPO SCV Interview Techniques (Gsp)

LS1-Fdb LPO SCV Feedback (Fdb)

LS1-Exc Excel Assignment (Exc)

LS1-FG1 Performance review 1 (FG1)

LS1-BEpos Poster Biobased economy

LSC1-BElec1 Guest lectures 1 Biobased economy

LSC1-BElec2 Guest lectures 2 Biobased economy

Weighting (Klab + Kwis) / 2

Compensation

possibilities

Klab = Klab2, except if Klab1 ≥ 5.5 then Klab = Klab2 +

1

Kwis = Kwis2, except if Kwis1 ≥ 5.5 then Kwis = Kwis2

+ 1

Klab1 and Kwis1 are valid for 1 year

Entrance conditions for

examination

Klab and Kwis must be ≥ 5.5 Kvei must be ≥5.5 prior to starting the practical of 2nd year Performance review 1, Guest lectures 1 and 2


4

Biobased economy, Biobased economy poster, Excel assignment, Interview techniques and Feedback must be Satisfactory

Frequency (modular)

examinations

LS1-Klab1 and LS1-Kwis1: period 1, period 3

LS1-Klab1 and LS1-Kwis1: period 2, resits during

period 3, period 4, resit end period 4

LS1-Kvei: period 1, resit periode 1, during period 3,

resit end period 3

LS1-BElec1: Term 1 and/or 2 (8 lectures given

over the course of Terms 1 and 2) LSC1-BElec2: Term 1 and/or 2 (8 lectures given

over the course of Terms 1 and 2) LS1-BEpos: Term 1 or 2, resit in consultation

with lecturer (SLB) For the Biobased economy guest lectures, at least 2 of the 8 lectures in period 1 and 2 must be attended. In Term 3 and 4 there are no opportunities.

For participation in the workshops and modular

examinations Klab1 and Kwis1 there is one chance

per academic year (OS art. 7.3). Participation in Klab1 and Kwis1 is only possible in the first year of enrolment.

13. Compulsory

literature

See #OnderwijsOnline

14. Recommended

literature

-

15. Software

16. Other material In this course unit, multimedia tools are used to support the teaching, such as

PECUr Point, video en social media.

17. Activities See work forms

18. Work forms Supporting subject

Lab calculations

Density

Percentages and fractions

Atom mass, molecular mass and formula mass

Molar and molecular mass

Molecular- and mixture formulas

Mixing and dilution

Concentration and dilution

Reaction calculations

Teaching methods: combined lectures/response

classes

Supporting subject

Mathematics

Basic calculation rules

Logarithms

PECUrs

pH calculations

Trigonometry

Solving equations

Quadratic functions

Differentiation


classes


5

Supporting subject

Safety

Laboratory Rules

Safe handling of materials

Waste categories

Practical rules/accident or incident

Working methods: Response lectures and work

discussion in the lab

Supporting subject

Workshop Excel

Data entry

Formatting

Formulas and function

Graphs and trendlines

Teaching methods: workshop in computer room

Supporting subject:

Communication

LPO SCV Interview Techniques

This workshop focuses on interview techniques.

Participation is compulsory and is checked off in

Alluris.

LPO SCV Feedback

This workshop focuses on giving and receiving

feedback and cooperation. Participation is

compulsory and is checked off in Alluris.

Procedure : workshop

Supporting subject

Biobased economy

Introduction: Biobased economy

Working methods: Response lectures and guest

lectures

19. Lesson / contact

hours

Planned lesson/contact hours

approximately 9 lesson periods per week, approx. 63 lesson periods per term 1 =

approx. 47 hours

approximately 8 lesson periods per week, approx. 56 lesson periods per term 2 =

approx. 41 hours

Planned time for self-study:

Term 1 = 58 hours

Term 2 = 64 hours

Total: 210 hours

20. Teaching period Term 1 and 2

21. Maximum

number of

participants

not applicable.


6

Assessment programme course unit 1: Basic knowledge for Life Sciences (LS1) Carrying out scientific research: Basic knowledge for Life Sciences

COURSE UNIT

Modular examinations

Indicators Assessment criteria Weighting and pass mark

Code:

LS1-Klab

LS1-Klab1

LS1-Klab2

Name:

LS1-Klab: Theory exam lab

calculations

LS1-Klab1:Theoretical exam

1 lab calculations

LS1-Klab2: Theoretical exam

2 lab calculations

Form:

LS1-Klab:

Administrative

LS1-Klab1 and LS1-Klab2:

Individual

In writing

Open Questions

Weighting:

LS1-Klab: 1

LS1-Klab1: 0

LS1-Klab2: 0

Assessment:

Grade

Lower limit:

LS1-Klab: 5.5

LS1-Klab1: 0

LS1-Klab2: 4.5

Knowledge of lab calculations

knows the elementary calculation rules and the relevant laboratory core relationships.

has insight into the relations between several key relations

The student is able to:

systematically work out problems in lab work using elementary calculation rules and the several core relationships.

systematically work out problems with chemical reactions using several core relationships.

conversion of units

calculate volume and mass using density of a solution;

perform calculations with percentages and fractions;

calculate atomic mass, molecular mass and formula mass of a substance;

perform calculations with mol and molecular mass;

calculate molecular and empirical formulas of a a substance;

calculate the concentration of a substance after mixing and dilution;

calculations with reactions.

Exam matrix

Conversion of units approx. 10%

Isolation of units approx. 10%

Density, percentage and fractions

approx. 10%

Mol and molecular mass approx. 20%

Mixing and dilution approx. 20%

Molecular and mixture formulas

approx. 10%

Calculations with reactions approx.

20%.

Klab:

Klab = Klab2, but if Klab15.5; then Klab

= Klab2 + 1.

Klab1 and Klab2:

- 55% for Satisfactory (5.5)

Participation in Klab1 is only possible in

the first year of enrolment.

Code:

LS1-Kwis

LS1-Kwis1

Knowledge of mathematics Commands sufficient basic maths skills:

calculation: estimating calculations, working with fractions;

pECUrs, positive and negative whole exponents and fractional

Exam matrix

~50% algebra

~30% analysis


7

LS1-Kwis2

Name:

LS1-Kwis: Theoretical exam

Mathematics

LS1-Kwis1: Theoretical exam

Mathematics 1

LS1-Kwis2 Theoretical exam

Mathematics 2

Form:

LS1-Kwis:

Administrative

LS1-Kwis1 and LS1-Kwis2:

Individual

In writing

Open Questions

Weighting:

LS1-Kwis: 1

LS1-Kwis1: 0

LS1-Kwis2: 0

Assessment:

Grade

Lower limit:

LS1-Kwis: 5.5

LS1-Kwis1: 0

LS1-Kwis2: 4.5

exponents;

factor analysis and removing brackets;

Trigonometry in a triangle, degrees and radians Additionally, the student:

can draw graphs of trigonometric functions and determine with given parameters, the amplitude, period, frequency and equilibrium of the function;

understands that a letter in a formula represents a variable and can perform calculations with this.

can draw a graph of a function, including a 1st degree, 2nd degree, rational function or pECUr function and can calculate specific points (like intersections with the X-axis and Y-axis);

can write the equation of a line;

can work with the abc formula.

recognises exponential and logarithmic functions and can work with these;

can determine the derivative of pECUr functions, trigonometrical functions, exponential and logarithmical functions.

~20% Trigonometry

Kwis = Kwis2, except if Kwis15.5; then

Kwis=Kwis2+1

Kwis1 and Kwis2:

- 55% for Satisfactory (5.5)

Participation in Kwis1is only possible in

the first year of enrolment.

Code:

LS1-Kvei

Name:

Theory exam Safety

Form:

Individual

Written

Multiple choice

Weighting:

Competence 4: Quality control

4.1.1. Is aware of the safety (work) and environment rules and

works accordingly

Knowledge of safety in the lab.

The student:

can apply general and specific laboratory rules;

is familiar with safety equipment available and how they should be used;

recognize the safety symbols, GHS pictograms dangerous substances and knows how to act appropriately;

know the short- and long-term effects of harmful substances on the human body and the environment;

knows the definitions of safety concepts: MAC-value, LD50-value, R and S statements and can apply them;

can estimate fire and explosion risk based on physical fire related concepts;

can look up safety information on substances in MSDS sheets

Exam matrix

- 10% laboratory rules - 50% safe handling of materials - 15% waste categories - 25% Practical rules/accident or

incident

Pass mark: 70% correctly answered is

equivalent to 5.5


8

0

Assessment:

Grade

Lower limit:

5.5

and chemistry charts;

knows and recognises the biological agents

knows the rules on “safe microbiological techniques”;

knows the rules on processing lab waste (chemicals and biological agents);

can indicate how first aid should be applied in lab situations;

Code:

LS1-Gsp

Name:

Discussion Skills:

Form:

Individual

Oral

Weighting:

0

Assessment:

Satisfactory/unsatisfactory

Lower limit:

S.

Competence 8: Teamwork / communication

Functioning in a group

8.1.1. Observes the rules.

8.1.2. Makes a clear contribution to the group.

Communication

Communicates his task to fellow students and lecturer according to

the basic rules of communication; if needed, supervised by the

lecturer.

8.1.3. Maintains eye contact with conversation partner.

8.1.4. Allows others to finish speaking.

8.1.5. Verbalises his/her opinion/messages.

8.1.6. Is open to, and offers feedback.

Participation in the Feedback Workshop is compulsory. Participation in the workshop and

completion of the task are both

required for a satisfactory assessment.

Code:

LS1-Fdb

Name:

Feedback

Form:

Individual

Oral

Weighting:

0

Assessment:


Lower limit:

Competence 8: Teamwork / communication



8.1.2. Makes a clear contribution to the group.

Communication



lecturer.


Participation in the Feedback Workshop is compulsory. Participation in the workshop and

completion of the task are both



9

S.

Code:

LS1-Exc

Name:

Assignment Excel

Form:

Individual

In writing

Weighting:

0

Assessment:


Lower limit:

Satisfactory

Knowledge of Excel The student is able to in Excel:

Enter data;

Formatting cells

Writing formulas and functions and editing

Drawing and using graphs and trendlines

Excel assignment must be submitted for

a satisfactory

Code:

LS1-BEpos

Name:

Poster Biobased economy

Form:

In writing

In duo

Weighting:

0

Assessment:


Lower limit:

Satisfactory

The student:

can use an example to explain problems of the current

economy;

knows the most important principles of the Biobased economy;

can explain in general terms what the importance of a Biobased

economy is and the role that Life Sciences and Chemistry can

have in it.

See assessment form below ‘Biobased economy poster’. See assessment form below ‘Biobased

economy poster’.

Satisfactory: at least 6 Criteria from

‘Content’ and 3 Criteria from ‘Layout’

are Satisfactory.

Code:

LS1-BElec1

LS1-BElec2

The student:

can use an example to explain problems of the current

economy;

knows the most important principles of the Biobased economy;

Registration, attendance and participation at two of the six guest

lectures.

Registration, attendance and

participation at two guest lectures is



10

Name:

Attending Guest lectures 1

and 2

Form:

Individual

Weighting:

0

Assessment:


Lower limit:

Satisfactory

can explain in general terms what the importance of a

Biobased economy is and the role that Life Sciences and

Chemistry can have in it.

Code:

LS1-FG1

Name:

Performance review 1

Form:

Individual

Oral

Weighting:

0

Assessment:


Lower limit:

Satisfactory

Competence 11: Professional development

11.1.3. Takes a critical look back (reflects) on their own actions and

learning process; learns from his mistakes.

11.1.4. Has general higher education study skills; self-motivated,

has determination.

See assessment form below ‘Performance review, level I’

3 performance interviews per year (start of academic year, end of

semester 2, end of foundation year).

See assessment form below

‘Performance review, level I’

All criteria must be Satisfactory for an

overall satisfactory grade.


11

Assessment form Poster Biobased economy Year 1

Name: ……………………………………………………… Class: ………………. Date: ..........……………….

Poster title:

Criteria Unsatisfactory satisfactory

Content:

A correct example of a fossil fuel product is presented. A photograph of this product is present on the poster.

The production process of this product is described.

The advantages and disadvantages of the (production of) this product is described.

A correct example of a biobased product is correctly presented.

A photograph of this product is present on the poster.

The production process of this product is described.

The advantages and disadvantages of the (production of) this product is described.

Layout of the Poster (A3 format):

The text is easy to read.

The poster is visually attractive and well presented

The poster appears interesting and novel

The ratio of images and text is balanced.

Final assessment (Satisfactory: at least 6 Criteria from ‘Contents’ and 3 Criteria from ‘Lay-out’ are Satisfactory)

Feedback

Study coach name and signature:


12

Assessment form: Performance review 1st year

Name:………………………………………………………... Class: ………………. Date:

..........……………….

Competency indicator Assessment criterion Unsatisfactory Satisfactory

8.1.1. Observes the rules. Students meets agreements, is punctual, and

has completed the preparatory assignment

(e.g. DPF is orderly).

11.1.3. Takes a critical look back

(reflects) on their own actions and

learning process; learns from his

mistakes.

The student methodically takes a critical look

at his/her learning process, identifies what

went well, and what didn’t go well, identifies

the causes of these, and links it to his/her

own actions. A plan for improvement in the

future is formulated.

11.1.4. Has general higher

education study skills: self-

motivated, has determination.

The student shows a pro-active attitude and

is motivated.

He/she shows determination in his study.

Final assessment

(for and overall satisfactory assessment, all individual components must be

satisfactory)

Feedback


Institute of Applied BioSciences and Chemistry Degree Charter Biology and Medical Laboratory Research; Life Sciences Description of the education 2017-2018 Chapter 2: Course Units and Integral Assessments of the Foundation Year

13

Course unit title Course unit 2a: Basic practical skills Chemistry, Biology & Medical ECU 2a: Basic practical skills Chemistry, Biology & Medical

Code LS2a


2. Target group Full-time students common foundation year - Biology and Medical Laboratory

Research, Life Sciences, Chemistry


professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

-

6. Study credits,

study load

7.5 stp

210 SBU

7. Cohesion with

other course units

Course 2a is related to Course 2b and 2c. The practical of LS in course unit2a is linked

with the theory LS in course unit2b. The chemistry practical of course unit2a is linked

with the chemistry theory in course unit2c.

8. Prerequisites

in relation to

(modular)

examinations

To participate in LS2a-LS2a-Pb and Pc, attendance at the practical lessons mandatory.

HAVO diploma (higher general continued education) or higher, with the profile Nature

and Technology or Nature and Health.

9. General

description

Practical Biology & Medical

Students work on basic biology

knowledge from different

vantage points. Both

prokaryotic and eukaryotic cells

and tissues are covered.

Practical Chemistry

Students work on the synthesis and analysis of

different food additives. These include vitamins,

minerals, dyes, aromas and preservatives.

10. Competence Designing an experimental plan

Experiment

Results analysis

Quality control

Management and administration

Reporting and presenting

Planning and project-based working

Professional development

11. Assessment

criteria

See assessment program for description of exams, exam form, assessment criteria

and indicators

12. Assessment Modular examinations LS2a-Pb Practical grade Biology and

Medical (Pb)

LS2a-Pc Practical Grade Chemistry (Pc)

Weighting (Pc + Pb)/2

Compensation possibilities -


examination

Pb and Pc both ≥ 5.5

Frequency (modular)

examinations

LS2a-Pb: Term 1 or 2

LS2a-Pc: Term 1 or 2

For the modular examinations Pb and Pc there is

only one chance per academic year (EER art. 7.3).

When the practical test is missed due to illness

and the student has officially reported sick, or

personal circumstances (for review to the course

Institute of Applied BioSciences and Chemistry Degree Charter Biology and Medical Laboratory Research; Life Sciences Description of the education 2017-2018 Chapter 2: Course Units and Integral Assessments of the Foundation Year

14

coordinator and/or Examination Board) then the

student has the right to another chance.

13. Compulsory

literature


14. Recommended

literature

-

15. Software See #OnderwijsOnline

16. Other material Tablet

In this course unit, multimedia tools are used to support the teaching, such as

PowerPoint, video and social media.


18. Work forms Practical Biology & Medical

Histological staining

Cytology

Microbiology

Molecular techniques

Microscopy

Biochemical techniques

Teaching methods: lab practicals

Practical Chemistry

Weighing, pipetting, titration

Dilution, Spectrophotometry

Synthesis: reflux, melting point, refractive

index, IR spectrometry, TLC



hours

Practical Biology and Biomedical

Research


Avg. 8 periods (lesson hours) per

week= 56 periods in term 2 = 42 clock

hours per term

Planned time for self-study: 63 clock

hours per term

Total: 105 hours

Practical Chemistry


Avg. 8 periods (lesson hours) per week= 56

periods in term 2 = 42 clock hours per term

Planned time for self-study: 63 clock hours

per term

Total: 105 hours


21. Maximum

number of

participants

not applicable.

Institute of Applied Biosciences and Chemistry Degree Charter Part 3: Biology and Medical Laboratory Research; Life Sciences Description of the education 2017-2018 Chapter 2: Course Units and Integral Assessments of the Foundation Year

15

Assessment programme course unit 2a: Basic practical skills Chemistry, Biology & Medical (LS2a)

Carrying out life science research COURSE UNIT Modular examinations


Code: LS2a-Pb Name: Practical grade Biology and Medical Form: Individual Practical In writing Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.4. Formulates a corresponding hypothesis based on the given research question. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. 2.1.4. Conducts experiments accurately according to the protocol. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results Competence 4: Quality control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly Competence 5: Management and administration 5.1.1. Labels the chemicals and samples and stores these in prescribed manner. 5.1.2. Leaves the work space cleaned and tidied. 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:

uses correct spelling and grammar;

is aware of scientific style in writing;

applies simple and logical structure;

describes results so that the reader can understand these; uses for this clearly labelled figures and tables.

6.1.3. Is familiar with the international conventions of scientific and academic writing. Competence 7: Planning and project-based working 7.1.3. Executes work according to a plan. Competence 11: Professional development 11.1.4. Has general higher education study skills: self-motivated, has determination. In the context of:

Assessment of “Lab Practical Course 2 Life Science” (see evaluation form below).

Practical exam: The student performs one or more individual experiments carried out during the hours of practical lessons. The student is assessed on the execution of the experiment and the lab journal with the results and discussion sections.

Grade ‘Pb’ is the average of the assessment “Practical Course: 2 Biology & Medical” and practical assessment. Pass mark: 55% is equivalent to 5.5


16

Histology staining Cytology Microbiology Molecular techniques Microscopy Biochemical techniques

Code: LS2a-Pc Name: Practical skills Chemistry Form: Individual Practical In writing Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.4. Formulates a corresponding hypothesis based on the given research question. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. 2.1.4. Conducts experiments accurately according to the protocol. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results Competence 4: Quality control 4.1.1. Is aware of and adheres to the workplace health and safety rules. 4.1.2. Calibrates simple equipment (pH meters, pipettes). Competence 5: Management and administration 5.1.1. Labels the chemicals and samples and stores these in prescribed manner. 5.1.2. Leaves the work space cleaned and tidied. 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:





Competence 7: Planning and project-based working 7.1.3. Executes work according to a plan. Competence 11: Professional development 11.1.4. Has general higher education study skills: self-motivated, has determination. In the context of: Acids and bases

See the assessment form below for Practicals Chemistry with lab journal The final 3 measurement reports are assessed with unsatisfactory, satisfactory or good. See assessment form below for Data report level I

Grade Pc = Grade from the assessment form “Chemistry Practical with lab journal” This grade is completed with the result from “Assessment Form Data Report Level I”. With a ‘Satisfactory’, the final grade is equal to the grade as given in the assessment form; with a ‘Good’, 0.5 points is added to the grade to reach the final grade. Pass mark: 55% is equivalent to 5.5 Additionally, the measurement reports must all be at least satisfactory


17

Electrochemistry Organic Chemistry


18

Assessment form Practical course 2a Biology & Medical

Name: ……………………………………………………………………………………………............. Class: …………………… Date: ……………………

Related to competences

Assessment criterion Unsatisfactory Satisfactory Good Excellent Number points

LAB JOURNAL

5.1.3. The student writes a lab journal with title, aim and materials & method.

1 or more of the components is missing or

incorrect

-0-

All components are present but contain some errors

-2-

All components are present and mostly correct

-3-

All components are present and always correct

-3-

1.1.4. The student formulates a hypothesis relating to the given research question.

Hypothesis missing

-0-

Hypothesis is sometimes incorrect

-2-

Hypothesis is often correct -3-

Hypothesis is always correct

-4-

2.1.2. The student performs calculations prior to beginning lab work.

Preliminary calculations are missing

-0-

Preliminary calculations sometimes contain mistakes

-2-

Preliminary calculations are usually correct

-2-

Preliminary calculations are always correct

-3-

2.1.1. The student can answer questions on the theoretical background of the experiment orally and in writing.

Questions are not answered, or often

incorrectly answered -0-

Questions are sometimes answered incorrectly

-2-

Questions are mostly answered correctly

-2-

Questions are always answered correctly

-2-

3.1.1. The student records results clearly and comprehensively in the lab journal and analyses these in the correct manner.

Results are incomplete and unclear

-0-

Results are complete and clear but the analysis

sometimes contains errors -2-

Results are complete and clear and the analysis is

often correct -3-

Results are complete and clear and the analysis is always

correct -4-

2.1.4. The results agree with the theoretical expectations. Results are incomplete or often do not agree with the

expectations -0-

Results sometimes do not agree with the expectations

-2-

Results often agree with the expectations

-3-

Results are always in agreement with the

expectations

-4-


19

2.1.1. 3.1.4.

In the discussion section of the lab journal, the student explains the results by relating the theoretical background of the experiment to the execution.

Link between theory and execution is often not well

made -0-

Link between theory and execution is sometimes not

well made -6-

Link between theory and execution is usually made

well -8-

Link between theory and execution always made well

-10-

3.1.3. The student draws correct conclusions based on the results. Conclusions are absent or often incorrect

-0-

Conclusions sometimes have errors

-6-

Conclusions are usually correct

-8-

Conclusions are always correct

-10-

5.1.1. 5.1.3.

The student labels and stores chemicals and samples in a prescribed way and notes this in his/her lab journal.

Unsatisfactory

Satisfactory

6.1.1. The lab journal is well-structured.

Lab journal is very disorganised

-0-

Lab journal is well organised

-6-

Lab journal is orderly

-8-

Lab journal is exceptionally orderly

-10-

LAB ACTIVITIES

4.1.1. The student works according to the health and safety regulations.

Unsatisfactory

Satisfactory

5.1.2. The student leaves the workplace tidy and clean. Not Satisfactory

Satisfactory

2.1.4. The student knows on which step of an experiment he/she is working on.

Often does not know what step he/she is working on

-0-

Sometimes does not know what step he/she is working

on -6-

Often knows what step he/she is working on

-8-

Always knows what step he/she is working on

-10-

7.1.3. The student carries out the experiments within the planned time frame and according to the planning.

Often runs over time -0-

Sometimes runs over time -6-

Never runs over time -8-

Is exceptionally efficient -10-

11.1.4. The student is on time, prepared, has the right equipment and adopts an active work attitude.

Often has an unsatisfactory work attitude

-0-

Usually has a satisfactory work attitude

-6-

Always has sufficient work attitude

-8-

Always has a satisfactory work attitude and helps others

-10-

Total number of points

Final assessment (total number of points / 8 AND all are satisfactory)

Lecturer name and initials:


20

Assessment Form Practical Exam Course 2a Biology & Medical

Name: …………………………………………………………….………………. Class: ………………. ………………………………………. Date:....................

Related to competences


LAB JOURNAL


1 or more of the components is missing

or incorrect -0-

All components are present but contain

some errors -2-

All components are present and mostly

correct -3-

All components are present and always

correct -3-


Hypothesis missing

-0-


-2-

Hypothesis is often correct

-3-


-4-



-0-

Results are complete and clear but the

analysis sometimes contains errors

-2-

Results are complete and clear and the

analysis is often correct -3-


always correct

-4-

2.1.1. 3.1.4.

In the discussion section of the lab journal, the student explains the results by relating the theoretical background of the experiment to the execution.

Link between theory and execution is often not

well made -0-

Link between theory and execution is sometimes

not well made -6-

Link between theory and execution is usually

made well -8-

Link between theory and execution always made

well -10-

3.1.3. The student draws correct conclusions based on the results.

Conclusions are absent or often incorrect

-0-


-6-


-8-


-10-

Specific Contents experiment 1

Experiment title: -0- to -9-

Specific Contents experiment 2

Experiment title: -0- to -9-

6.1.1. The lab journal is well-structured.

Lab journal is very disorganised

-0-


-6-

Lab journal is well organised and tidy

-8-


-10-


21

LAB ACTIVITIES

4.1.1. The student works according to the health and safety regulations.

Unsatisfactory -0-

Satisfactory -2-

5.1.2. The student leaves the workplace tidy and clean. Needs to be reminded to clean up and does not

leave workplace clean and tidy.

-0-

Needs to be reminded to clean up and leaves

workplace clean and tidy.

-1-

Takes the initiative to clean up own area

-3-

Takes the initiative to clean up own and general

areas

-4-

The student works independently. Student needs help with a

crucial step in the experiment

-0-

Student asks several

content-related questions

-1-

The student asks a content-related

question

-3-

The student works completely

independently and does not require help.

-5-

7.1.3. The student carries out the experiments within the planned time frame and according to the planning.

One of the experiments is incomplete

-0-

The experiments are almost completed

-6-

The experiments are finished on time

-8-

Is very efficient

-10-


Final assessment (Total number of points / 8)

Lecturer name and initials:


22

Assessment form LS2a: Chemistry Lab Practical

Name: ……………………………………………….………………. Class: ………………. Date:....................

Related to comp./ indicators


LAB JOURNAL



incorrect

-0-

All components are present but contain some

errors -2-

All components are present and mostly

correct -3-


-3-


Hypothesis missing

-0-


-2-


-3-


-4-



-0-

Preliminary calculations sometimes contain

mistakes -2-


-2-


-3-





-2-


-2-


-2-



-0-

Results are complete and clear but the analysis sometimes contains

errors -2-


often correct

-3-


always correct

-4-

2.1.4. The results agree with the theoretical expectations.

Results are incomplete or often do not agree with

the expectations -0-


-2-


-3-


expectations -4-

5.1.1. 5.1.3.


Unsatisfactory Satisfactory

6.1.1. The lab journal is well-structured. Lab journal is very disorganised

-0-


-6-


-8-


-10-


23

LAB ACTIVITIES

4.1.2. The student uses equipment correctly (eg. calibrate pH meters)

Often makes mistakes when calibrating

-0-

Sometimes makes mistakes when calibrating

-8-

Always calibrates equipment correctly

-11-

Always calibrates equipment correctly

-15-

4.1.1. The student works according to the health and safety regulations,

Unsatisfactory

Satisfactory

5.1.2. The student leaves the workplace tidy and clean.

Often does not tidy away the materials used

-0-

Sometimes tidies away the materials used

-5-

Always tidies away the materials used

-7-

Always tidies away the materials used and regularly

contributes to tidying the lab. -10-

2.1.4. The student can explain which step in an experiment he/she is working on.

Usually unable to explain the step he/she is working

on -0-

Sometimes unable to explain which step he/she

is on -10-


-15-

Is always able to explain which step is being done

-20-

2.1.5. 7.1.3.

The student carries out the experiments within the planned time frame and according to the planning.

Often runs over time -0-


Never runs over time -8-

Is exceptionally efficient -10-

11.1.4. The student is on time, prepared, has the right equipment and adopts an active work attitude.

Often has an unsatisfactory work

attitude -0-

Usually has a satisfactory work attitude

-8-

Always has satisfactory work attitude

-11-

Always has a satisfactory work attitude and helps

others -15-


Final assessment (Total number points/10 and all are satisfactory)

Feedback

Assessor name and initials


24

Assessment form Data report Level I

Name:………………………………………………... Class: ………………. Date: ..........……………….

Competence/

indicator

Assessment form Data report Level I I S G

Introduction:

Aim of the research and methods

1.1.4 Hypothesis (if possible)

2.1.1 Reaction equation (if applicable)

2.1.2 Calculation formulas (with explanation of symbols and units correctly expressed)

Materials and methods

2.1.3 Requirements

Chemicals (brand, date, concentration, lot number)

Equipment (brand, HAN serial number)

Setup (if applicable)

2.1.2., 2.1.3 Methods

References to the protocol and changes

Calibration series for standards in a table

Preliminary calculations (if applicable; e.g. pre-weighing)

Results

3.1.1. Mostly in tables and graphs. Tables and graphs are numbered and have a title and are accompanied by text

3.1.1. Uses a table with an overview of the results

3.1.1, 3.1.2 Example calculations, error calculations are correct (including significance and units)

Discussion

3.1.2, 3.1.4 Interprets the usability of the results.

Any abnormalities are reported

Conclusion

3.1.3. Makes conclusion based on the results

A statement is made concerning the hypothesis

There is a clear cohesion between goal, hypothesis and conclusion

Style

referencing literature according to APA guidelines/Communication for laboratory engineers

6.1.1. Uses correct spelling and grammar, writes in formal language

6.1.1. Applies simple and logical structure

Assessment: UNSATISFACTORY/SATISFACTORY/GOOD

The assessment is the average of all criteria and is sufficient with a satisfactory or good.

Feedback



25

Course unit title Course unit 2b: Basic theory Biology and Medical Course unit 2b: Basic theory Biology and Medical

Code LS2b


2. Target group Full-time students common foundation year - Biology and Medical Laboratory Research,

Life Sciences, Chemistry


professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Presentation LS (Prb)

6. Study credits,

study load

7.5 stp

210 SBU

7. Cohesion with

other course units

Course 2b is related to the practical LS Course 2a. The theory offered in Course 2b is

related to the lab practicals in Course 2a

8. Entry

requirements for

(modular)

examinations

Attendance at the tutor groups is a prerequisite for participation in the modular

examination IPS.

HAVO (higher general continued education) diploma with the profile Nature and

Technology or Nature and Health,

MBO diploma level 4

9. General

description

Students work on basic biology knowledge from different vantage points. Both

prokaryotic and eukaryotic cells are covered, plant and animal tissues and several

metabolic routers. The overall theme is energy.


Experiment

Results analysis

Quality control



Teamwork

Managing professional development

11. Assessment

criteria

See assessment program for description of exams, exam form, assessment criteria and

indicators

12. Assessment Modular examinations LS2b-Tb Theme test (T2)

LS2b-Kb Theory exam (Kb, Ktt, Ket)

LS2b-Prb Presentation (Prb)

LS2b-IPV IPS

Weighting (Kb + Tb + Prb)/3 ≥ 5.5

Compensation possibilities Kb = Ket. if Ktt ≥ 5.5 then Kb = Ket + 1 Ktt is valid for 1 year.


examination

Tb ≥ 5.5

Kb ≥ 5.5

Prb ≥ 5.5

IPS passed (week assignments are part of IPS)

Frequency (modular)

examinations

LS2b-Tb: Term 1, resit term 2, term 2, resit during

term 3

LS2b-Ktt: Terms 1 or 2

LS2b-Ket: Term 1, resit Term 2

Period 2, resit period 3

LS2b-Prb: Term 1 or 2, resit in consultation with

lecturer


26

LS2b-IPV: Terms 1 or 2

There is only one opportunity per year for the modular

exams IPS and Ktt (OS art. 7.3) Participation in Ktt is only

possible in the first year of enrolment.

13. Compulsory

literature


14. Recommended

literature





Powerpoint, video en social media.


18. Work forms Supporting subjects Biology Cells

Macromolecules

Tissues

Digestion

Photosynthesis

Cell respiration

Combined lectures/response classes

Supporting subject

Theory of the lab practicals

Theoretical background to lab practice


Tutor Introduction and preparation of weekly

assignments

Methods: Meetings


hours

Lesson/contact hours

8 lesson hours (periods) per week; 56 lesson hours per term= 42 clock hours

Scheduled time for constructing exams:

6 lesson hours (periods) =4.5 clock hours


163.5 clock hours

Total: 210 hours

20. Teaching period Terms 1 or 2

21. Maximum

number of

participants

not applicable.


27

Assessment programme course unit 2b: Basic theory Biology and Medical (LS2b) Carrying out life science research COURSE UNIT

Modular examinations


Code:

LS2b-Kb

LS2b-Ktt

LS2b-Ket

Name:

LS2b-Kb: Theory exam

LS2b-Ktt: Theoretical exam 1

LS2b-Ket: Theoretical exam 2

Form:

LS2b-Kb

Administrative

LS2b-Ktt and

LS2b-Ket

Individual

In writing

Multiple choice

Weighting:

LS2b-Kb: 1

LS2b-Ktt: 0

LS2b-Ket: 0

Assessment:

Grade

Lower limit:

LS2b-Kb:5.5

LS2b-Ktt: 0

LS2b-Ket: 4.5

Knowledge of ‘basic cell and tissue biology’ and ‘background theory

belonging to the processes taking place in the lab experiments’

Introduction Cell Biology and histology (Biology)

The student has:

knowledge eukaryotic cell structure and function;

knowledge of differences between the prokaryotic and eukaryotic cell;

knowledge of the structure and function of macromolecules;

knowledge of the structure and function of plant tissues;

knowledge of the structure and function of animal tissues;

knowledge of food digestion in (enzymatic) breakdown of macromolecules;

knowledge of photosynthesis in plants;

knowledge of cellular respiration in animal cells.

Background theory of experiments (theory for practicals)

The student has:

knowledge of DNA isolation;

knowledge of determination of macromolecules;

knowledge of cell and tissue staining;

knowledge microscope use;

application of prior calculations for experiments;

knowledge of starch digestion and determination;

knowledge urine composition;

knowledge of fermentation

Kb = Ket: If Ktt 5.5 then Kb = Ket + 1

65 (± 5)% basic cell biology and histology

35 (± 5)% Background theory experiments

Ktt and Ket:

70% for Satisfactory (5.5)

Code:

LS2b-Tb

Name:

Theme test

Competence 1: Design

1.1.4. Formulates a corresponding hypothesis based on the given

research question.

1.1.5. Integrates information into a simple research plan.

1.1.6. Understands and applies English literature relevant to the given

Basic cell and tissue biology (Biology) and tutor tasks

The student has:

knowledge eukaryotic cell structure and function;

knowledge of differences between the prokaryotic and eukaryotic cell;

50 (± 5)% basic cell biology and histology

(Biology) and Tutor tasks.

50 (± 5)% Background theory experiments.

Pass mark: 55% for Satisfactory (5.5)


28

Form:

In writing

Open Questions

Individual

Weighting:

1

Assessment:

Grade

Lower limit:

5.5

context.

Competence 2: Experiment

2.1.1. Reads the lab protocols, understands them; understands the

theoretical background of the main steps.

2.1.2. Performs calculations prior to beginning lab work.

Competence 3: Results analysis

3.1.1. Analyses the results appropriately according to the prescribed

methods.

3.1.3. Draws conclusions regarding the research question (if possible).

Competence 4: Quality control

4.1.1. Is aware of and adheres to the workplace health and safety

rules.

In the context of: Histology staining Cytology Microbiology Molecular techniques Microscopy Biochemical techniques

knowledge of the structure and function of macromolecules;

knowledge of the structure and function of plant tissues;

knowledge of the structure and function of animal tissues;

knowledge of food digestion in (enzymatic) breakdown of macromolecules;

knowledge of photosynthesis in plants;

knowledge of cellular respiration in animal cells;

knowledge of transcription and translation in animal cells;

knowledge of Diabetes Mellitus;

knowledge of MET values and can apply them in calculations.

Background theory of experiments (theory for practicals)

The student:

understands the background theory of the experiments;

can perform calculations in preparation;

interprets results and can perform calculations;

can make correct conclusions based on results.

Code:

LS2b-Prb

Name:

Presentation

Form:

Oral

Group (pairs)

Weighting:

1

Assessment:

Grade

Lower limit:

5.5

Competence 1: Design

1.1.1 Independently identifies relevant background information required to answer the research question. 1.1.2 Knows the criteria for reliable sources in life science research

Competence 6: Reporting and presenting

6.1.3. Presents research to audience with a similar background

following the criteria of presentation techniques and answers

questions:


describes results so that the reader can understand these; uses for this purpose clearly labelled figures and tables;

there is structure in the presentation (head-body-tail);

speaks clearly and intelligibly;

stands upright and keeps hands relaxed; makes eye contact with the audience

makes well-structured and clear slides or other visual products Competence 8: Teamwork



lecturer.




See Evaluation form “Presentation course 2” 55% for Satisfactory (5.5)


29

In the context of:

Structure of plant, animal, bacterial, fungal and yeast.

Transcription and translation in animal cells.

Structure and function of animal tissues

Research to diagnose diabetes mellitus

CO2 cycle.

Code:

LS2b-IPV

Name:

IPS

Form:

Oral

Individual

Weighting:

0

Assessment:

Satisfactory/

Unsatisfactory

Lower limit:

Satisfactory

Competence 7: Planning and project-based working

7.1.3. Executes work according to a plan.

Competence 8: Teamwork



8.1.2. Makes a clear contribution to the group

Communication



lecturer.





Competence 11: Professional development

11.1.4. Has general higher education study skills; self-motivated, has

determination.

11.1.6. Is aware of the international market of the profession

The student:

the student adheres to the rules agreed upon (k.o.);

Fulfils his/her roles (Chair, secretary etc.);

the student has prepared for the meeting by completing the assignment to be discussed, and also completed the required reading for the following assignment to be discussed.

the student is able to show weekly assignments to the tutor (according to agreement, in writing or as a presentation); in all assignments all required aspects are complete;

asks questions and shares knowledge regarding the assignment during tutor meetings; verbalises these clearly and audibly, maintains eye contact;

allows others to finish speaking;

the student offers feedback to group and class members and is open to receiving feedback.

Group members evaluate de effort and commitment of the

student (IRIS).

All knock-out criteria and 70% of the other

criteria must be satisfied to get 'Satisfactory'


30

Evaluation form “Presentation course 2b”

Name student: .................................................Class: ………………Date: …………………

Competence Assessment criteria

Max

Number

of points

Points

awarded

1.1.1, 1.1.2 Contents

Three or more of the following subjects are presented:

Structure of plant, animal, bacterial, fungal and yeast cells.

Transcription and translation in animal cells.

determination of DNA

Research to diagnose diabetes mellitus

CO2 cycle.

Makes a clear link between the subjects listed above and the greater research context that the student has chosen.

30

20

6.1.3. Presentation

There is structure in the presentation.

Make well-structured and clear slides or other visual products:

Uses correct spelling and grammar.

Describes results so that the audience can understand them; uses for this clearly labelled pictures and tables.

Speaks clearly and intelligibly.

Stands upright and keeps hands relaxed, or uses them appropriately.

Makes eye contact with the audience.

Makes verbal contact with the public at suitable moments

20

20

8.1.3, 8.1.4, 8.1.5 Discussion

Keeps eye contact with partner and lets others finish speaking.

Supports own opinion clearly with well-justified arguments.

Asks content-related questions at other presentations

10

Total number of points 100

Final assessment (total number of points / 10)

Feedback

Name of the lecturer and initials:


31

Course unit title Course unit 2c: Basic Theory Chemistry ECU 2c: Basis theory Chemistry

Code LS2c


2. Target group Full-time students common foundation year - Biology and Medical Laboratory Research,

Life Sciences, Chemistry


professional tasks Carrying out life science research

4. Central

professional task

Not applicable.

5. (Professional)

Products

Presentation Chemistry (Prc)

6. Study credits,

study load 7.5 stp

210 SBU

7. Cohesion with

other course units

Course 2c is related to the practical Chemistry Course 2a. The theory offered in Course 2c

is related to the lab practicals in Course 2a

8. Entry

requirements in

relation to

(modular)

examinations


Technology or Nature and Health,

MBO diploma level 4

Attendance at the tutor groups is a prerequisite for participation in the modular

examination IPS.

9. General

description

Students work on different aspects in chemistry. Students work on the synthesis and

analysis of different food additives. These include vitamins, minerals, dyes, aromas and

preservatives.


Experiment

Results analysis

Quality control



Teamwork


11. Assessment criteria

See assessment program for description of exams, exam form, assessment criteria and

indicators

12. Assessment Modular examinations LS2c-Tc Theme test (T2)

LS2c-Ktt Theory exam 1 Chemistry (Ktt)

LS2c-Ket Theory exam 2 Chemistry (Ket)

LS2c-Kc Theory exam Chemistry (Kc)

LS2c-Prc Presentation Chemistry (Prc)

LS2c-IPV IPS

Weighting (Kc + Tc + Prc)/3 ≥ 5.5

Compensation possibilities Kc = Ket. if Ktt ≥ 5.5 then Kc = Ket + 1

Ktt is valid for 1 year.


examination

Kc, Tc and Prc ≥ 5.5

IPS passed (week assignments are part of IPS)

Frequency (modular)

examinations

LS2c-Tc Term 1, term 2, resit term 2 or 3

LS2c-Ktt Terms 1 or 2

LS2c-Ket Term 1, term 2, resit term 2 or 3

LS2c-Kc Term 1, term 2, resit term 2 or 3

LS2c-Prc Terms 1 or 2

LS2c-IPV Terms 1 or 2


32

There is only one opportunity per year for the modular

exams Ktt and IPS (OS art. 7.3) Participation in Ktt is only

possible in the first year of enrolment.

13. Compulsory

literature


14. Recommended

literature

-




Powerpoint, video and social media.


18. Work forms Supporting subjects: Chemistry theory Fundamentals: Basic chemistry

Strong acids and bases + titration (also weak

acids)

Spectrophotometry

Redox reactions

Organic chemistry: functional groups and

nomenclature


Supporting subjects: Theory of the lab

practicals

Theoretical background to lab practice



hours


9 lesson hours (periods) per week + 5 assessment hours; 68 lesson hours per term = 51

clock hours


159 hours

Total: 210 hours


21. Maximum

number of

participants

not applicable.


33

Assessment programme course unit 2c: Basic theory Chemistry (LS2c) Carrying out life science research COURSE UNIT Modular examinations


Code: LS2c-Ktt LS2c-Ket LS2c-Kc Name: Theory exam 1 Chemistry (Ktt) Theory exam 2 Chemistry (Ket) Theory exam Chemistry (Kc) Form: LS2c-Ktt Individual In writing Open Questions LS2c-Ket Individual In writing Open Questions LS2c-Kc Administrative Weighting: LS2c-Ktt: 0 LS2c-Ket: 0 LS2c-Kc: 1 Assessment: Grade Lower limit: LS2c-Ktt: 0 LS2c-Ket: 4.5 LS2c-Kc: 5.5

Knowledge of chemistry:

Basic chemistry

Acids and bases

Electrochemistry

Spectrometry

Organic Chemistry:

Basic chemistry The student is able to:

able to describe how an atom or simple ion is structured;

draw ratio formulas of ion and molecule formulas of molecules;

naming cations, anions ion compounds and inorganic compounds or vice versa;

calculate using the formulas c= n/V and m=n*Mm

predict the possible reaction between 2 substances and balance the reaction equation;

calculating and working with precipitation reactions (balancing equations, calculate hvh, predict precipitate)

Acids and bases The student is able to:

balance acid-base reactions and identify acids and bases;

calculates the pH and pOH of a solution of strong acids and bases;

calculate the concentration H3O+ and OH- from the pH and Kw;

calculation of pH at every point in a titration of a strong acid with a strong base or vice versa;

calculate the volume of titrant at the end point of the titration.

Electrochemistry The student is able to:

identifying an oxidizer and a reducing agent of the oxidation and reduction reaction by the determination of the oxidation numbers of the elements in a compound;

make balanced redox reactions on the basis of half-reactions.

Spectrometry The student is able to:

knows the relationship between wavelength and energy;

Calculate using the Lambert-Beer Law;

convert extinction to transmission and vice versa. Organic Chemistry The student is able to:

identify two molecules as structural isomers or stereoisomers;

if Ktt ≥ 5.5 then Kc = Ket+1. Pass mark: 55% correctly answered is equivalent to 5.5 Ktt Basic chemistry: Approx. 70% Electrochemistry: approx. 30% Ket Basic chemistry approx. 20% Acids and bases: approx. 20% Electrochemistry: approx. 20% Spectrometry: approx. 20% Organic Chemistry: approx. 20%


34

draw hydrocarbons with and without functional groups on the basis of the name and determine whether the name is correct;

nomenclature of hydrocarbons with and without functional groups;

recognising and naming functional groups (haloalkane, alcohol, ether, phenol, aldehyde, ketone, carboxylic acid, amine, amide or ester);

predict the influence of hydrogen bridges on the physical properties of organic molecules/describe trends in physical properties of alkanes;

drawing the structure formula of an ester or an amide from the reaction of an alcohol and acid, or an amine and an acid (and vice versa).

Code: LS2c-Tc Name: Theme test Chemistry Form: Individual In writing Open Questions Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.4. Formulates a corresponding hypothesis based on the given research question. 1.1.5. Integrates information into a simple research plan. 1.1.6. Understands and applies English literature relevant to the given context. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.3. Draws conclusions regarding the research question (if possible). Competence 4: Quality control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly Competence 7: Planning and project-based working 7.1.1. Plans and organises his activities resulting in a work plan In the context of:

Basic chemistry

Acids and bases

Spectrometry

Organic Chemistry:

The student:

lists important safety aspects of chemicals;

notes relevant information of chemicals on a safety form;

chemical compounds are correctly named;

explains which particles precipitate in a reaction and which remain in solution;

is able to explain which particle remains in solution;

is able to write an ionic equation;

proposes a correct reaction equation or ion equation for a precipitation reaction;

performs calculations on various types of reactions;

is able to select relevant information from articles and express in for example, molecular and structural formulas, and reaction equations;

correctly writes molecular formulas;

draws a block diagram of a spectrophotometer;

explains the mechanism of the different components of a spectrophotometer;

explains the background of UV/VIS spectrometry;

can draw up a calibration curve from data points;

can calculate the concentration of a substance from a calibration curve using Beer's Law;

draws chemical structures of organic substances in the correct manner;

makes a distinction between different organic compounds based on characteristic groups (e.g. alcohol, acid, ester);

chemical compounds are correctly named;

can write a correct reaction equation with structure formulas for the synthesis of an ester;

performs correct calculations on acid-base titrations.

The subjects listed in the section ‘In the context of’ are represented evenly in the exam. Pass mark: 55% correctly answered is equivalent to 5.5 Safety: ca 5% Nomenclature: ca 5% Calculations on comments/precipitation reactions: ca 15% Spectrophotometry approx. 30% acid-base titrations approx. 25% Organic Chemistry approx. 20%


35

Code: LS2c-Prc Name: Presentation Chemistry Form: Oral Group (pairs) Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in the product criteria for lab journal / report level 1: 6.1.3. Presents research to audience with a similar background following the criteria of presentation techniques and answers questions:





stands upright and keeps hands relaxed;

makes eye contact with the audience

makes well-structured and clear slides or other visual products Competence 8: Teamwork Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking. 8.1.5. Verbalises his/her opinion/messages. In the context of (Body of Knowledge and Skills)

Organic Chemistry:

Acids and bases

Spectrometry

See assessment form “Presentation course 2 Chemistry” See assessment form “Presentation course 2 Chemistry” Pass mark: 55% is equivalent to 5.5

Code: LS2c-IPV Name: IPS Form: Individual Oral Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 7: Planning and project-based working 7.1.3. Executes work according to a plan. Competence 8: Teamwork Functioning in a group 8.1.1. Observes the rules. 8.1.2. Makes a clear contribution to the group Communication Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking. 8.1.5. Verbalises his/her opinion/messages. 8.1.6. Is open to, and offers feedback. Competence 11: Professional development 11.1.4. Has general higher education study skills; self-motivated, has determination. 11.1.6. Is aware of the international market of the profession

The student:

adheres to the rules agreed upon (k.o.);

fulfils his/her roles (Chair, secretary etc.);

the student has prepared for the meeting by completing the assignment to be discussed, and also completed the required reading for the following assignment to be discussed.

is able to show weekly assignments to the tutor (according to agreement, in writing or as a presentation); in all assignments all required aspects are complete;



offers feedback to group and class members and is open to receiving feedback.

Group members evaluate de effort and commitment of the student (IRIS).

All knock-out criteria and 70% of the other criteria must be satisfied to get 'Satisfactory'


36

Evaluation form “Presentation course 2C” Name:………………………………………………... Class: …………. Date:....................

* It is possible that students give a presentation on another subject. The assessment of the content will also be different.

Related to comp./

indicators

Assessment criteria Max Number of points

Points awarded

Content*

The following subjects are presented:

Brief introduction with info from weekly assignments about benzoic acid/4-Hydroxybenzoic acid;

synthesis of benzoic acid/4-Hydroxybenzoic acid with reaction equation;

titration of benzoic acid/4-Hydroxybenzoic acid with results;

spectrophotometric analysis of benzoic acid/4-

Hydroxybenzoic acid with results.

Compares and discusses the results of the titration and spectrophotometric analysis and draws conclusions.

30

20

6.1.3. Presentation

There is structure in the presentation (head-body-tail).



Describes results so that the audience can understand them; uses for this clearly labelled pictures and tables.

Speaks clearly and intelligibly.




20

20

8.1.3, 8.1.4, 8.1.5

Discussion

Keeps eye contact with partner and lets others finish speaking.

Supports own opinion clearly with well-justified arguments.

Asks content-related questions at other presentations

10


Final assessment (total number of points / 10)

Feedback



37

Course unit title Course unit LS3K: Knowledge of molecular biology and biochemical research of DNA and protein ECU LS3K: Knowledge of molecular biology and biochemical research of DNA and protein

Code LS3K

1. Degree Life Sciences, BML

2. Target group Full-time Students Main phase - Biology and Medical Laboratory Research, Life

Science level 1

MLO transfer students


professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Not applicable.

6. Study credits,

study load

5 stp

140 SBU

7. Cohesion with

other course units

LS3 builds on LS2a, b and c and prepares for the main phase of Life Science. LS3 is

divided into three course units, each worth 5 study credits. LS3K (Knowledge), LS3P

(practical), LS3T (theme, project).

8. Entry

requirements

regarding

(interim) exams

HAVO (higher general continued education)/VWO (pre-university) diploma with the

profile Nature and Technology or Nature and Health, and course units LS1, LS2a,

LS2b and LS2c.

Participants MLO-flow-through program or shortened route for secondary school

students or MLO'ers.

9. General

description

In this course unit, students learn about the molecular and biochemical properties of

the biomolecules RNA, DNA and protein, and about the processes that are involved

in the production of these biomolecules. Students learn to use databases and IT tools

to analyse DNA, RNA and proteins. The theory behind important methods are

discussed that are integral to the research of biomolecules.

10. Competence Design

11. Assessment

criteria


indicators.

12. Assessment Modular examinations LS3K-Bi Bioinformatics Assessment en Assignments (Bi)

LS3K-K Theory exam (K)

Weighting Final grade:

(2*K + Bi)/ 3

Compensation

possibilities

-

Entrance conditions

for examination

All grades must be ≥ 5.5

Frequency (modular)

examinations

Term 3, term 4, resit during term 4 or end of term 4

13. Compulsory

literature


14. Recommended

literature



38


16. Other material Laptop or tablet



Cell Biology

Structure of the cell

Properties of DNA, RNA, protein, lipids and carbohydrates.

Genetic code

Replication, transcription, translation:

Comparison of gene expression in prokaryotes and

eukaryotes

Mutations

Working methods: combined lectures/response classes

Supporting subject

Bioinformatics

Biological database

Bioinformatics web portals

CLC Bio

Genetische Code, determination of Open Reading Frames

Restriction enzyme analysis

Primer design and analysis

Protein analyses

Working methods: response classes

Supporting subject

Chemistry

Chemical bonds

Weak acids and bases

Buffers

Properties of proteins

Working methods: combined lectures/response classes

Supporting subject

Physics

Centrifugation

Electrophoresis

Fluorescence

Working methods: lecture

Workgroups

Practical theory /

expert

Theoretical background and designing experiment plan for

protein isolation, protein purification, protein concentration

measurement, SDS PAGE

Using and referencing sources of literature



hours


Avg. 8 lesson hours per week, 6 clock hours per week

total 56 lesson hours (periods) /week= 42 hours per term


Total: 140 hours


21. Maximum

number of

participants

not applicable.


39

Assessment programme course unit LS3K: Knowledge of molecular biology and biochemical research of DNA and protein (LS3K)

Carrying out life science research Modular examinations


Code: LS3K-Bi Name: LS3K-Bi Bioinformatics Assessment

and Assignments Form: Individual In writing Open Questions Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.3. Consults simple but relevant scientific sources. In the context of:

Biological databases and analysis tools for gene and protein sequences

Restriction maps and in silico restriction analysis

PCR primer analysis

Protein analyses

The student:

searches in biological databases e.g. for articles, gene and protein sequences;

identifying gene sequences and perform a nucleotide blast to determine whether a nucleotide sequence comes from a specific organism and/or codes for a (part of) the gene.

Learns to work with analysis software to nucleotide sequences to import and editing;

makes restriction maps and determines sizes of restriction fragments;

Can detect an ORF from nucleotide sequences using CLC bio and translate to the protein encoded; then study the molecular mass, isoelectric point and amino acid composition.

develops primers for PCR;

determine the molecular mass and isoelectric point of proteins;

analyzes known protein sequences and can determine in which organisms that protein is found.

Grade for Final Assessment is as follows: Pass mark final assessment = 55%. The grade is only awarded if all self-study assignments have been satisfactory. All self-study assignments are satisfactory and submitted via email and/or OnderwijsOnline.

Code: LS3K-K Name: LS3K-K Theory exam Form: LS3K-K: Individual In writing Open Questions Multiple choice Weighting: LS3K-K: 2

Knowledge of cell biology:

Biomolecules: DNA, RNA, protein, lipids and carbohydrates

Replication

transcription

RNA processing

translation

the genetic code:

mutations

Biomolecules The student:

names the structure and properties of the biomolecules DNA, RNA, protein, carbohydrates and lipids.

makes statements about the percentage of adenine, cytosine, guanine or thymine in a double-stranded DNA molecule;

predicts, on the basis of the properties of biomolecules their localization and possible function in the cell and vice versa.

Replication, transcription, RNA processing, translation The student:

has knowledge and insight in replication, transcription, RNA processing and translation of prokaryotes and eukaryotes;

Genetic code The student:

applies knowledge of the genetic code and gene expression in

multiple choice: 70% pass mark:, open questions 55% pass mark. 60% of the key consists of multiple choice questions and 40% of the key consists of open questions. Exam matrix 45-55% cell biology (multiple choice); 5-15% physics/theory underlying practical work (multiple choice); 35-45% Chemistry (open questions).


40

Assessment: Grade Lower limit: LS3K-K: 5.5

order to make statements about RNA and protein sequences on the basis of DNA sequences and vice versa; and on the consequences of changes in DNA, RNA or protein in cells;

Names and describes different types of mutations and mutations in different DNA sequences and explains the possible consequences for a cell.

Knowledge of chemistry:

Chemical bonds

Weak acids and buffers

Properties of proteins

Separation techniques

The student:

Has knowledge of atomic composition and types of molecular bonds and can apply this to draw Lewis structures and determine dipolar moments: Describes the composition and properties of molecular bonds, ion bonds, covalent bonds.

can perform pH calculations for weak acids, weak bases and buffers.

has knowledge of amino acids and protein and can calculate the load of proteins as a function of the pH

has knowledge of separation techniques and can apply it to a determine the elution order of a mixture or to determine a strategy to separate a mixture.

Knowledge of Physics / Theory behind practical:

Centrifugation;

Electrophoresis;

Fluorescence

DNA isolation and analysis:

Protein isolation, purification and determination

Centrifugation: The student:

has understanding of the forces that work on a particle in a solution;

knows what influences the sedimentation speed

knows centrifugation methods and understands the relationship between rpm, RCF and r (radius of the centrifuge) and can calculate these.

Electrophoresis: The student:

understands movement of ions in an electrical field;

has knowledge and understanding of agarose and polyacrylamide gel electrophoresis.

understands the aspects regarding heat development,

endosmosis and use of buffers;

has knowledge and insight in the influence of load, size and shape of molecules (DNA, RNA and proteins) on the mobility.

Fluorescence The student:

know the relationship between the wavelengths of light and the resolution;

knows the concept and the differences between excitation, fluorescence emission;

understands the aspects of a light source, RGB, monochromator, splitters, filters, and cross-talk with


41

fluorescence; Isolation and analysis of DNA and protein: The student:

knows methods for the isolation and analysis of DNA and protein, and then apply this knowledge in practical questions.


42

Course unit title Course unit LS3P: Practical molecular biology and biochemical research on DNA and protein ECU LS3P: Practical molecular biology and biochemical research of DNA and protein

Code LS3P

1. Degree Life Sciences


Science level 1



professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Not applicable.

6. Study credits,

study load

5 stp

140 SBU

7. Cohesion with

other course units




8. Entry

requirements

regarding

(interim) exams



LS2b and LS2c.

MLO transfer students, accelerated route for MLO or VWO students

Attendance at the practical lessons is a prerequisite for participation in the modular

examination PL (Practical with lab journal).

9. General

description



in the production of these biomolecules. In the practical, important methods are

performed that are integral to research of biomolecules. The experiments are

planned partially by the students in a research plan.


Experiment

Quality control

Results analysis




Teamwork


11. Assessment

criteria


indicators.

12. Assessment Modular examinations LS3P-PL Practical with lab journal (PL)

Weighting Final grade: LS3P-PL

Compensation

possibilities

-

Entrance conditions All grades must be ≥ 5.5


43

for examination

Frequency (modular)

examinations

Terms 3 or 4

There is only one opportunity per academic year for the

modular exams PL (OS art. 7.3)

13. Compulsory

literature


14. Recommended

literature



16. Other material Laptop or tablet


18. Work forms Practicals DNA isolation

Agarose gel electrophoresis

Restriction digestion

PCR

Protein extraction

Protein purification

Protein concentration determination

SDS-PAGE

Teaching methods: lab practicals and lab journal

Workgroups

Practical theory /

expert







hours


Avg. 11 lesson hours per week, 8.25 clock hours per week

total 140 lesson hours (periods) /week= 58 hours per term


Total: 140 hours


21. Maximum

number of

participants

not applicable.


44

Assessment programme course unit LS3P: Practical molecular biology and biochemical research on DNA and protein (LS3P)

Carrying out life science research Modular examinations Indicators Assessment criteria Weighting and pass mark

Code: LS3P-PL Name: Practical with lab journal Form: Individual Practical In writing Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.4. Formulates a corresponding hypothesis based on the given research question. 1.1.6. Understands and applies English literature relevant to the given context. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. 2.1.4. Conducts experiments accurately according to the protocol. 2.1.5. Carries out the experiments within the stated time Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.2. Assesses the usability of the results based on of accuracy and reliability. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results Competence 4: Quality control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly Competence 5: Management and administration 5.1.1. Labels the chemicals and samples and stores these in prescribed manner. 5.1.2. Leaves the work space cleaned and tidied. 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:





Competence 7: Planning and project-based working 7.1.3. Executes work according to a plan. Competence 11: Professional development

See assessment form below for Practical with lab journal. See Assessment form below: Practical with lab journal, Level I, Term 3 and 4 5.5 points corresponds to a satisfactory (5.5), provided that all the components of the assessment form were evaluated as sufficient.


45

11.1.4. Has general higher education study skills: self-motivated, has determination. In the context of:

chromosomal DNA isolation

Plasmid DNA isolation

Restriction enzyme analysis of chromosomal and plasmid DNA

PCR

agarose gel electrophoresis

protein isolation

protein purification

protein determination

SDS-PAGE


46

Assessment form Practical with lab journal, Level I, Term 3 and 4 Name:………………………………………………... Class: ………………. Date:....................................................



LAB JOURNAL

5.1.3. 1.1.6

The student writes a lab journal with title and aim. 1 or more of the components is missing

or incorrect -0-


some errors -2-


-3-


-4-

1.1.4. 1.1.6

The student formulates a hypothesis relating to the given research question.

Hypothesis missing

-0-


-2-


-3-


-4-

5.1.3. 1.1.6

The student writes the methods and materials in the lab journal before the start of practical work.

Materials and methods are incomplete.

-0-

Materials and methods are clear, some pipetting

schemes are missing or changes are not recorded.

-2-

Materials and methods are often complete and

correct

-4-

Materials and methods are always correct, pipetting schemes are complete.

-6-



-0-


mistakes -1-


-2-


-3-

2.1.1. 1.1.6

The student can answer questions on the theoretical background of the experiment orally and in writing.



Questions are sometimes answered

incorrectly -1-


-2-


-2-



-0-

Results are complete but the analysis sometimes

contains errors -2-


often correct -4-


always correct -6-

3.1.2.

3.1.4.

In the discussion section of the lab journal, the student

explains the results and makes statements about the

accuracy and reliability.

Results are not

explained and there are

no statements made

about accuracy and

reliability

-0-

Results are partly


statements made about

accuracy and reliability

-6-

Results are partly


correct statements about


-8-

Results are completely


clear and correct

statements about accuracy

and reliability

-10-



-0-


-6-


-8-


-10-


47

5.1.1. 5.1.3.



6.1.1. 7.1.1.

The lab journal is well-structured and records the required preparations for the the practical work.

Lab journal is very disorganised and the

preparations are missing.

-0-

Lab journal is well organised and

sometimes records the required preparations.

-6-

Lab journal is well organised and records all

required preparations

-8-

Lab journal is exceptionally orderly and the

preparations are recorded in detail and in a timely

fashion. -10-

LAB ACTIVITIES

4.1.1. The student works according to the health and safety regulations, Unsatisfactory Satisfactory

5.1.2. The student leaves the workplace tidy and clean. Not Satisfactory Satisfactory

2.1.4. The results agree with the theoretical expectations. Results are incomplete or often do not agree with the expectations

-0-

Results are sometimes not in agreement with

the expectations -1-


-3-


expectations -5-


Usually unable to explain the step he/she

is working on -0-

Sometimes unable to explain which step

he/she is on -6-


-8-


-10-

2.1.5. 7.1.3.


Often runs over time

-0-


Never runs over time

-8-

Is exceptionally efficient

-10-

11.1.4 The student is on time, prepared, has the required equipment and adopts an active work attitude.


attitude -0-

Usually has a satisfactory work

attitude -6-


-8-


others -10-


Final assessment (total number points/9 and every component at least satisfactory)

Feedback



48

Course unit title Course unit LS3T: Molecular biology and biochemical research of DNA and protein ECU LS3T: Molecular biology and biochemical research of DNA and protein

Code LS3T



Science level 1



professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Research plan (Op)

6. Study credits,

study load

5 stp

140 SBU

7. Cohesion with

other course units




8. Entry

requirements

regarding

(interim) exams



LS2b and LS2c.

MLO transfer students, accelerated route for MLO or VWO students

Attendance at the tutor meetings is a prerequisite for participation in the modular

examination IPS.

9. General

description



in the production of these biomolecules. Students learn to use databases and IT tools

to analyse DNA, RNA and proteins. In the practical, important methods are

performed that are integral to research of biomolecules. The experiments are

planned partially by the students in a research plan. Students learn to use literature

to search for the theoretical background of the methods and thereby determine

which method is appropriate for their research purpose.


Experiment

Quality control

Results analysis



Teamwork


11. Assessment

criteria


indicators.

12. Assessment Modular examinations LS3T-IPV IPS

LS3T-Op Research plan (Op)

LS3T-T Theme test (T2)

Weighting Final grade:


49

(T + Op)/ 2

Compensation

possibilities

-

Entrance conditions

for examination

All grades must be ≥ 5.5 and IPS satisfactory

Frequency (modular)

examinations

Term 3, term 4, resit during term 4 or end of term 4

There is only one opportunity per academic year for the

modular exams IPV (OS art. 7.3)

13. Compulsory

literature


14. Recommended

literature






18. Work forms Workgroups

Tutor Assignments

Theoretical background DNA isolation

Using sources of literature

Designing experimenten plan for restriction enzyme analysis

PCR theoretical background

Designing experiments for PCR

Safety and lab calculations

Properties of proteins in solution


Results analysis

Methods: tutor meetings, interactive expert meetings, group

work

Workgroups

Research plan





Methods: group work, workshop: Design


hours


Avg. 3.5 lesson hours per week, 2.6 clock hours per week

total 24.5 lesson hours (periods) /term= 18.5 clock hours

Planned time for self-study: 121.5 full hours

Total: 140 hours


21. Maximum

number of

participants

not applicable.


50

Assessment programme course unit LS3T: Molecular biology and biochemical research of DNA and protein (LS3T)


Code: LS3T-Op Name: Research plan Form: Group In writing Weighting: 2 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.1. Independently identifies relevant background information required to answer the research question. 1.1.2. Knows the criteria for reliable sources in life science research. 1.1.3. Consults simple but relevant scientific sources. The sources of literature are presented in the assignment. 1.1.4. Formulates a corresponding hypothesis based on the given research question. 1.1.5. Designing experimental plan 1.1.6. Understands and applies English literature relevant to the given context. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. 2.1.3. Ensures that all requirements are ready before the experiment is started; makes solutions Competence 3: Results analysis 3.1.3. Draws conclusions regarding the research question (if possible). Competence 4: Quality control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly 4.1.3. Uses controls to evaluate the reliability of the results. Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:





6.1.3. Is familiar with the international conventions of scientific and academic writing. Competence 7: Planning and project-based working 7.1.1. Plans and organises his activities resulting in a work plan. Competence 8: Teamwork Functioning in a group 8.1.1. Observes the rules.

See also assessment form below for the Research plan ECU3LS. Exam matrix approx. 20% points theoretical background of methods; ~ 70% plan; ~ 10% structure/layout/writing 55 points corresponds to a satisfactory (5.5). (See assessment form below for the research plan).


51

8.1.2. Makes a clear contribution to the group In the context of:

Protein isolation


Protein determination

SDS-PAGE.

Code: LS3T-IPV Name: IPS Form: Individual Oral In writing Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 7: Planning and project-based working 7.1.2. Plans study activities 7.1.3. Executes work according to a plan. Competence 8: Teamwork Functioning in a group 8.1.1. Observes the rules. 8.1.2. Makes a clear contribution to the group Communication Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking 8.1.5. Verbalises his/her opinion/messages. 8.1.6. Is open to, and offers feedback. Competence 11: Professional development 11.1.4. Has general higher education study skills; self-motivated, has determination. 11.1.5. Is aware of internationally accepted codes of scientific conduct.

Compulsory attendance at tutor lesson (1 absence may be permitted with good reason; more than one absence results in an unsatisfactory (knock-out). The student:

has prepared for the meeting by completing the assignment to be discussed, and also completed the required reading for the following assignment to be discussed;

is able to show weekly assignments to the tutor (according to agreement, in writing or as a presentation); in all assignments all required aspects are complete;

fulfils his role(s) (e.g. chairperson, secretary, etc.; k.o.);





Group members evaluate de effort and commitment of the student as positive.

All knock-out criteria and 70% of the other criteria must be met for a 'Satisfactory' grade.

Code: LS3T-T Name: Theme test Form: Individual In writing Open Questions Weighting: 2 Assessment: Grade

Competence 1: Design 1.1.2. Knows the criteria for reliable sources in life science research. 1.1.3. Consults simple but relevant scientific sources. The sources of literature are presented in the assignment. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results Competence 4: Quality control 4.1.1. Is aware of and adheres to the workplace health and safety

The student:

can explain the basic steps of a protocol for DNA or protein isolation and evaluate whether an unknown protocol is suitable for these purposes;

knows the principles of PCR, restriction enzyme analysis, protein isolation methods, protein purification methods, terms and protein SDS-PAGE and can apply it in practice (e.g. controls, designing, experimenting, analyzing results and plans)

can perform calculations, in the context of practical examples, on DNA extraction and analysis and protein isolation, purification, identification and analysis.

makes a statement about safety measures for substances used in the practical based on the MSDS;

can make statements about properties of DNA, RNA and proteins

Exam matrix 5-10% points for safety and work planning; 10-20% points results analysis; 15-25% points for calculations; Other points for design and background of the methods. Final Grading: 55% of the points needed for a sufficient (5.5).


52

Lower limit: 5.5

rules. Competence 7: Planning and project-based working 7.1.1. Plans and organises his activities resulting in a work plan. In the context of:

isolation of chromosomal and plasmid DNA

determination of DNA concentration and purity

Restriction enzyme analysis

PCR

agarose gel electrophoresis

protein isolation



SDS-PAGE

properties of DNA, RNA, proteins


53

Assessment form Research plan course unit 3LS

Name:………………………………………………... Class:……………. Date:....................

Indicator Assessment criterion Max Number of

points

Number of points

Part 1

1.1.1 The research aim is described. 2

1.1.1, 1.1.3, 1.1.6, 2.1.1

It is justified with what methods the goal can be achieved and the underlying principles of the following methods:

protein isolation



protein analysis

4 2 4 2

Part 2

1.1.1 The research question is formulated. 1

1.1.4 The hypothesis(es) associated with the research questions is/are formulated.

2

1.1.5 The method is described in a flow chart for:

protein isolation



protein analysis

2 2 2 2

4.1.3. The required controls are described. 4

4.1.1. Relevant safety regulations are described and justified. 4

2.1.2, 2.1.3 The amount of reagents required and the sample is calculated for:

protein isolation



protein analysis

2 2 2 2

7.1.1. Time planning: activities are planned for each practical day. The dates of the practical days are listed.

4

3.1.3. It has been described under which circumstances the aim is reached/hypothesis is correct.

4

1.1.2 1.1.6 6.1.3.

The used sources of scientific literature are referenced in the text according to the APA guidelines:

the list is in alphabetical or chronological order;

references according to APA guidelines.

1 4

Structure / Layout / Writing

6.1.1. 6.1.3.

The report is written with correct spelling and grammar. More than 5 errors per page means that the report will not be assessed.

3

6.1.1. 6.1.3.

The plan is clearly structured using the indicated points. Page numbers are present.

3

7.1.1. 8.1.1 8.1.2.

The student has worked independently, has made a clear contribution to the work plan and has met the deadlines.

6


Grade (Total number of points / 6.6)

Feedback

Assessor Name and Signature


54

Course unit title Course unit LS4K: Knowledge about medical diagnostics ECU LS4K: Knowledge about medical diagnostics

Code LS4K


2. Target group

Full-time students Biology and Medical Laboratory Research, Life Sciences



professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Not applicable.

6. Study credits,

study load

5 stp

140 SBU

7. Cohesion with

other course units

LS4 builds on LS2a and 2b and prepares for the main phase.

LS4 is divided into three course units, each worth 5 study credits. LS4K

(Knowledge), LS4P (practical), LS4T (theme, project). LS4K is followed by LS4T and

LS4P.

8. Entry

requirements

regarding

(interim) exams

HAVO (higher general continued education)/VWO (pre-university) diploma

with the profile Nature and Technology or Nature and Health, and course units

LS1, LS2a, LS2b and LS2c.

MBO diploma level 4 and and course unit LS1, LS2a, LS2b and LS2c.


9. General

description

In this course unit, students learn about working in a medical laboratory and

become acquainted with medical diagnostics.

To gain knowledge about cells, their structure and function in the field of

medical microbiology, cytological and histological techniques.

10. Competence

11. Assessment

criteria


indicators.

12. Assessment Modular examinations LS4K-K Theory exam Microbiology /Cytology (K)

Weighting Final grade: K

Compensation

possibilities

-


examination

Theory exam grade must be ≥ 5.5

Frequency (modular)

examinations

Teaching period 3, resit period 4

Teaching period 4, resit period 4

13. Compulsory

literature


14. Recommended

literature




PowerPoint, video and social media.



Cytology

Cytology: The cell: form and function

Cells, tissues and organ systems

Cell cycle and tumor formation

Cellular signaling

The immune system

Heart and blood vessels, form and function


55


Supporting subject

Microbiology

Structure of bacteria cells

Metabolism of the bacteria cell

Microbiological growth

Infections: human and microorganism

contamination, pathogenicity, virulence, antibiotics,

chemotherapy

The role of microbiota



hours


4 lesson hours (periods) per week= 28 lesson hours per term = 21 clock hours

Planned time for self-study: 119 hours

Total: 140 hours


21. Maximum

number of

participants

not applicable.


56

Assessment programme course unit LS4K: Knowledge about medical diagnostics (LS4K)


Code: LS4K-K Name: Theory exam Form: In writing Multiple choice Individual Weighting: 1 Assessment: Grade Lower limit: 5.5

Knowledge of microbiology The student is able to:

name the components of the human cell and function of the various components;

explain various metabolisms of bacteria (including glucose metabolism);

can describe morphology and classification of bacteria;

name and explain the role of microbiota;

identify and explain the environmental factors and survival of bacteria, including extreme conditions (also under laboratory conditions);

interpret a bacterial growth curve and reproduce it;

calculate the generation time, the number of divisions and the number of cells for a given bacterial culture.

explain the different types of antibiotics and the effect on the bacterial cell;

explain how a bacterial cell protects itself from an antibiotic (resistance);

explain how the process of a urinary tract infection progresses with an explanation of the functions of the organs involved and diagnostics.

explain the role of bacteria in case of disease.

50% Cytology 50% Microbiology. Pass mark: 70% correctly answered is equivalent to a satisfactory (5.5).

Knowledge of cytology/histology The student is able to:

name the components of the human cell and function of the various components;

describe the structure of tissues and organ systems;

describe the structure, properties of membranes and transport processes;

explain how the form and function of human cells are necessary for life;

explain how cells communicate with each other and name the mechanisms;

identify the components of the cell cycle;

explain tumour growth, neoplasms and metastases;

name and explain the composition and properties of blood, and blood circulation;

explain how the immune system works;


57

Course unit title Course unit LS4P: Practical medical Diagnostics ECU LS4P: Practical medical diagnostics

Code LS4P


2. Target group




professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Labjournal as part of practical (P)

6. Study credits,

study load

5 stp

140 SBU

7. Cohesion with

other course units



(Knowledge), LS4P (practical), LS4T (theme, project). LS4P is followed by LS4T and

LS4K.

8. Entry

requirements

regarding

(interim) exams


with the profile Nature and Technology or Nature and Health, and course

units LS1, LS2a, LS2b and LS2c.

MBO diploma level 4 and and course unit LS1, LS2a, LS2b and LS2c.


LS4-P: attendance at practicals is compulsory. One missed practice session (with

good reason) can be caught up in the extra lesson provided. More missed

practical lessons results in no assessment carried out for LS4-P.

9. General

description


conducting research in the field of medical microbiology and cyto

histopathology.

To develop necessary competencies to perform the professional task, knowledge

gained about cells, their structure and function and practical skills are taught in

the field of medical microbiology, cytological and histological techniques.

10. Competence Experimenting

Research results analysis

Quality control




Teamwork

Advising


11. Assessment

criteria


indicators.

12. Assessment Modular examinations LS4P-P Practical assessment (P)

Weighting Final grade: P

Compensation

possibilities

-


58


examination

Practical grade must be ≥ 5.5.

Frequency (modular)

examinations

The practical is given in period 3 and in period 4.

There is only one opportunity per academic year for

the modular exams P (OS art. 7.3)

When the practical test is missed due to illness and

the student has officially reported sick, or personal

circumstances (for review to the course coordinator

and/or Examination Board) then the student has

the right to another chance.

13. Compulsory

literature


14. Recommended

literature



16. Other material A tablet or small laptop is used in the practical.



Practical work

Microscopic and macroscopic morphology

Microbiological techniques

Quantitative research

Determination of Gram positive and Gram negative

bacteria.

Bacterial urine test

Antibiotic determination

Cytology and histopathology

Blood: May-Grünwald staining, counting cells, blood

group typing


Supporting subject

Practical theory / expert

Theoretical background of the experiments


classes


hours


10 lesson hours/week, 70 lesson hours/period = 52.5 hours

Planned time for self-study: 87.5 hours

Total: 140 hours


21. Maximum

number of

participants

not applicable.


59

Assessment programme course unit LS4P: Practical medical Diagnostics (LS4P)


Code: LS4P-P Name: Practical Form: Practical Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.4. Formulates a corresponding hypothesis based on the given research question. Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. 2.1.4. Conducts experiments accurately according to the protocol. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results Competence 4: Quality control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly Competence 5: Management and administration 5.1.1. Labels the chemicals and samples and stores these in prescribed manner. 5.1.2. Leaves the work space cleaned and tidied. 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:





Competence 7: Planning and project-based working 7.1.3. Executes work according to a plan. Competence 11: Professional development 11.1.4. Has general higher education study skills: self-motivated, has determination. In the context of:

Products (See assessment forms below).

Conclusion about GMT, SMT experiments

Lab journal determination;

Lab journal staining;

Urinary tract infection form. Assessment Practical Level 1 (See assessment form below). Practical exam: The student individually executes one or more experiments that was also done in lab practical classes. The student is evaluated on the correct performance of the experiments according to the learned protocols and drawing the right conclusions.

P = (Average products + Assessment practical + practical exam)/3. Average products = (GMT, SMT Conclusion + lab journal determination + lab journal staining)/3. Urinary tract infection form must be Satisfactory. Practical exam: 55% is equivalent to 5.5 Practical must be ≥ 5.5. Practical exams and product ≥ 4.0. Exam matrix practical test: ~ 5% GMT, SMT ~ 16% Macroscopic morphology ~ 31% Determination ~ 16% histology ~ 16% urinary tract infection ~ 16% blood


60

safe microbiological techniques

good microbiological techniques

microscopy

microscopic morphology of bacteria

bacterial growth on different media

determination of Gram positive cocci

determination of Gram negative rods

histology techniques

cytological staining

histology staining

microbiological analysis of urinary tract infection

antibiotic sensitivity determination

blood group typing:

making and staining a blood smear

differential counting of leukocytes


61

Assessment form SMT conclusion LS4P Name:………………………………………………... Class:……………. Date:.................... Related to comp./ indicators

Assessment criterion Max Number of points

Points awarded

Contents

3.1.1. The results of the 6 GMT, SMT-experiments are succinctly described, but in such a way that the reader understands how the experiment was performed and what the results were.

10

3.1.3, 3.1.4 The correct conclusions are made form the results regarding the GMT, SMT guidelines:

effect of soap and Sterillium on the transient flora and resident flora (washing hands after work)

5

effect of ethanol on tissue on contaminated work surface (disinfection after work)

5

presence of bacteria on surfaces and the effect of disinfection (disinfection of work surfaces)

5

effect of hot inoculating loop (letting loop cool after heating to glowing point)

5

number of infected students after 2 rounds of shaking hands (wash hands after practical work)

5

mechanism of disinfectants on the tested bacteria (disinfection of surfaces)

5

6.1.1. The terms GMT, SMT, transient flora and resident flora are used in the right manner in the conclusion.

5


6.1.1. The report is written with correct spelling and grammar. More than 5 errors per page means that the report will not be assessed.

5

6.1.1. The conclusion is not longer than 1 A4 (typed). Satisfactory / Not Satisfactory


50

Grade (Number of points / 5)

Feedback



62

Assessment form ‘Urinary tract infection’ LS4P Name:………………………………………………... Class:……………. Date:.................... Related to comp./ indicators


Points awarded

Contents

3.1.1. The sample data (e.g. number, sex, date of birth, date of purchase, date of commencement, equipment, contributor) are correct.

2

5.1.3. The appearance of the urine is properly described (cloudy, clear, bloody, etc.).

3

5.1.3. Under Gram staining, the following is mentioned:

Colour and shape of the bacteria present

absence of bacteria (if applicable):

presence or absence of leukocytes

presence of erythrocytes and epithelial cells (if applicable)

5

3.1.1, 5.1.3 The date of commencement and evaluation of the culture plates are correctly noted: number of colonies and macroscopic morphology.

5

3.1.1. The counting of the culture plates is calculated correctly and precisely specified in count (m.o./ml).

5

2.1.4, 3.1.1 The next step taken in the labwork is chosen correctly, taking into account the count.

5

2.1.4 The identification (coloured row tests, determination of cocci) of the bacteria found is correctly noted.

5

5.1.3. The results of the resistance determination are noted in the correct manner.

5

3.1.3, 5.1.3 The result is correctly stated: date, number of m.o./ml, name, sensitivity and resistance

10


6.1.1. The form clearly and legibly filled in 5


50

Satisfactory ≥ 30 Points

Not Satisfactory (< 30 points)

Satisfactory (≥ 30 Points)

Feedback



63

Assessment form Lab Journal LS4P

Name: ……………………………………………………… Date: ……………………… Class: ………………. ………………………………………



5.1.3. The student writes a lab journal with title and aim. 1 or more of the components is missing or

incorrect -0-


-2-


-3-


-4-


Hypothesis missing

-0-


-2-


-3-


-4-

5.1.3.



-0-

Materials and methods are clear, some pipetting schemes are missing or changes are not

recorded. -3-

Materials and methods are often complete and correct

-4-


-6-


Questions are not answered, or often incorrectly

answered -0-


-2-


-3-


-4-



-0-

Results are complete and clear but the analysis sometimes

contains errors -2-

Results are complete and clear and the analysis is often

correct -3-


always correct -4-


Results are incomplete or often do not agree with the

expectations -0-


-2-


-3-


expectations -4-

2.1.1. 3.1.4.

In the discussion section of the lab journal, the student explains the results and makes statements about the accuracy and reliability.

Results are not explained

and there are no statements

made about accuracy and

reliability

-0-

Results are partly explained

and there are statements


reliability

-5-


and there are correct

statements about accuracy and

reliability

-6-


explained and there are clear

and correct statements about


-8-



-0-


-5-


-6-


-8-

5.1.1. 5.1.3.




64

6.1.1. The lab journal is well-structured and records the required preparations for the the practical work.



-0-

Lab journal is well organised and sometimes records the

required preparations.

-5-

Lab journal is well organised and records all required

preparations

-6-

Lab journal is exceptionally orderly and the preparations

are recorded in detail and in a timely fashion.

-8-


Final assessment (total number of points/5 AND all are satisfactory)

Feedback



65

Assessment form Practical work LS4P

Name: ……………………………………………………… Date: ……………………… Class: ………………. ………………………………………



LAB JOURNAL

5.1.3.

The student writes a lab journal with title and aim. 1 or more of the components is missing

or incorrect -0-


some errors -2-


-3-


-4-

1.1.4.

The student formulates a hypothesis relating to the given research question.

Hypothesis missing

-0-


-2-


-3-


-4-

5.1.3.



-0-

Materials and methods are clear, some pipetting schemes are missing or

changes are not recorded. -2-

Materials and methods are often complete and

correct

-4-


-6-



-0-


mistakes -1-


-2-


-3-

2.1.1.

The student can answer questions on the theoretical background of the experiment orally and in writing.




incorrectly -1-


-2-


-2-



-0-

Results are complete but the analysis sometimes

contains errors -3-


often correct -4-


always correct -6-

3.1.2.

3.1.4.

In the discussion section of the lab journal, the

student explains the results and makes statements

about the accuracy and reliability.

Results are not


no statements made

about accuracy and

reliability

-0-

Results are partly




-6-

Results are partly




-8-



clear and correct

statements about accuracy

and reliability

-10-







66

-0- -6- -8- -10-

5.1.1. 5.1.3.



6.1.1. 7.1.1.

The lab journal is well-structured and records the required preparations for the the practical work.



-0-

Lab journal is well organised and

sometimes records the required preparations.

-6-

Lab journal is well organised and records all

required preparations

-8-

Lab journal is exceptionally orderly and the

preparations are recorded in detail and in a timely

fashion. -10-

LAB ACTIVITIES

4.1.1. The student works according to the health and safety regulations, Unsatisfactory Satisfactory

5.1.2. The student leaves the workplace tidy and clean. Not Satisfactory Satisfactory


Results are incomplete or often do not agree with the expectations

-0-

Results sometimes do not agree with the

expectations -2-


-3-


expectations -5-



is working on -0-


he/she is on -6-


-8-


-10-

2.1.5. 7.1.3.


Often runs over time

-0-


Never runs over time

-8-

Is exceptionally efficient

-10-



attitude -0-


attitude -6-


-8-


others -10-


Final assessment (total number points/9 and every component at least satisfactory)

Feedback



67

Course unit title Course unit LS4T: Medical diagnostics ECU LS4T: Medical Diagnostics Project

Code LS4T


2. Target group




professional tasks


4. Central

professional task

Not applicable.

5. (Professional)

Products

Report (V)

Advice Presentation (AP)

6. Study credits,

study load

5 stp

140 SBU

7. Cohesion with

other course units



(Knowledge), LS4P (practical), LS4T (theme, project). LS4T is followed by LS4K and

LS4P.

8. Entry

requirements

regarding

(interim) exams


with the profile Nature and Technology or Nature and Health, and course units

LS1, LS2a, LS2b and LS2c.

MBO diploma level 4 and course unit LS1, LS2a, LS2b and LS2c.


LS4-IPV: presence in tutor lessons are compulsory.

9. General

description


become acquainted with medical diagnostics.

To develop necessary competencies to perform the professional task, knowledge

gained about cells, their structure and function and practical skills are taught in

the field of medical microbiology, cytological and histological techniques.

Regarding the competence "research analysis", a report is created containing an

analysis of experimental data. Advice is given based on a case study.

10. Competence Experimenting

Research results analysis

Quality control




Teamwork

Advising


11. Assessment

criteria


indicators.

12. Assessment Modular examinations LS4T-T Theme test (T2)

LS4T-V Research report (V).

LS4T-AP Advice Presentation (AP)

LS4T-IPV IPS

LS4T-HBO Competency card LS4T-St Mini-internship (St) LS4T-POP PDP LS4T-FG2 Performance review 2 (FG2)

LS4T-FG3 Funct.Gespr.3 (FG3)

LS4T-LPO SCV Ch Conflict management (Ch)


68

Weighting Final grade: (2V + 2T + AP) / 5

Compensation

possibilities

-


examination

IPS, performance review, workshops, professional

products and competency card must be ticked off

with ‘Satisfactory’ and assessment

grades/professional products ≥ 5.5.

Frequency (modular)

examinations

Term 3 of 4, resit Term 4

There is only one opportunity per academic year for

the workshops and modular exams IPS (EER art. 7.3)

13. Compulsory

literature


14. Recommended

literature






18. Work forms Tutor meetings

Tasks and assignments in the areas of:

Microbiology, histology and medical diagnostics

Methods: tutor meetings

Workshop

Working safely with

biological agents

Risk and safety, risk analysis

Pathogens, physical containment, biological

containment

Risk classes and containment levels

GMT, SMT in practice

Teaching methods: training

Workshops

Results analysis

Interpretation of research results

Drawing the correct conclusions from results

Results analysis


Workshop

Conflict management

Conflict management



~ 5 lessons/week, 35 lessons /period = 26 hours

Planned time for self-study: 114 hours

Total: 140 hours


hours

Terms 3 or 4

20. Teaching period not applicable.

21. Maximum

number of

participants


69

Assessment programme course unit LS4T: Medical diagnostics (LS4T)


Code: LS4T-V Name: Research report Form: In writing Group Weighting: 2 Assessment: Grade Lower limit: 5.5

Competence 1 Designing 1.1.1. Independently identifies relevant background information required to answer the research question. Competence 2: Experimenting 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. Competence 3: Results analysis Data processing 3.1.1. Analyses the results appropriately according to the prescribed methods. Validation 3.1.2. Assesses the usability of the results based on of accuracy and reliability. Conclusions and discussion. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results (if applicable). Competency 5 Management and administration 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6 Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:





In the context of:

Determining colony forming units

OD measurement

Determines specific growth rate and generation time of a bacterial culture

Contents The student:

explains the principle behind the methods (OD measurement and determining colony forming units);

Determines the number of bacteria at various time points;

draw a growth curve;

determines the specific growth rate;

determines the generation time;

takes the accuracy and reliability of all determinations/measurements into careful consideration;

concludes about the generation time and growth rate of the culture based on the reliability and accuracy of the data;

analyses errors and makes suggestions for follow-up experiments.

Text

The report is structured according to the provided points and written with correct spelling and grammar. The description of tables and figures are according to prescribed standards.

See assessment form below ‘Research report:Course 4LS.

80% Content 20% Text See assessment form below ‘Research report:Course 4LS.

Code: LS4T-IPV

Competence 8: Teamwork Functioning in a group 8.1.1. Observes the rules.

The student:

has prepared for the meeting by completing the assignment to be discussed, and also completed the



70

Name: IPS Form: Oral Individual Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

8.1.2. Makes a clear contribution to the group Communication Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner; 8.1.4. Allows others to finish speaking 8.1.5. Verbalises his/her opinion/messages. 8.1.6. Is open to, and offers feedback. Competence 11: Professional development 11.1.4. Has general higher education study skills; self-motivated, has determination. Competence 7: Planning and project-based working 7.1.3. Executes work according to a plan.

required reading for the following assignment to be discussed;

is able to show weekly assignments to the tutor (according to agreement, in writing or as a presentation); all required aspects are complete in all assignments;





offers feedback to group- and class members and is open to receiving feedback.

Group members evaluate de effort and commitment of the student (IRIS).

Code: LS4T-T Name: Theme test Form: In writing Individual Weighting: 2 Assessment: Grade Lower limit: 5.5

Competence 2: Experiment 2.1.1. Reads the lab protocols, understands them; understands the theoretical background of the main steps. 2.1.2. Performs calculations prior to beginning lab work. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.2. Assesses the usability of the results based on of accuracy and reliability. 3.1.3. Draws conclusions regarding the research question (if possible). Competence 4: Quality control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly 4.1.3. Uses controls to evaluate the reliability of the results. In the context of:

safe microbiological techniques

good microbiological techniques

determination of disinfection sensitivity

microscopic morphology of bacteria

Bacterial growth on different media

determination of Gram positive cocci

determination of Gram negative rods

histology techniques

microscopy

cytological staining

histology staining

microbiological analysis of urinary tract infection

The student:

describes and explains the rules and measures regarding safe and good microbiological techniques;

can perform calculations based on tests in the practical (dilution series, colony forming units);

recognizes and describes the microscopic morphology of the bacteria that were introduced in the practical;

knows the definition of and differences between selective, elective and enriched media, and can describe the properties of these.

describes the steps in the identification of Gram positive cocci and Gram negative rods and draws the right conclusion of the results;

describes the different steps in microbiological research of urinary tract infections and draws the right conclusions;

describes the steps and background of the cytological and histological stains and microscopy that have been introduced in the practical;

recognizes and describes the different components of blood and understands how a blood type determination works;

describes the structure and function of intestinal epithelium and the relationship between structure and function;

describes the symptoms, the cause and diagnosis of a patient with coeliacs or urinary tract infection.

Exam matrix 5-10% safety 5-10% Calculations. 50-60% for the context subjects and the microbiology applications. 40-50% for the context subjects and the cytohistology applications. 55% for Satisfactory (5.5)


71

antibiotic sensitivity determination

blood group typing:

making and staining a blood smear

differential counting of leukocytes

Ssructure and function of animal cells

coeliac disease

Code: LS4T-AP Name: Advice Presentation Form: Oral Group Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 6: Reporting and presenting 6.1.3. presents research to an audience with a similar background according to the criteria of presentation techniques and answers questions:







makes well-structured and clear slides or other visual products Competence 8: Cooperation / Functioning in a group 8.1.2. Makes a clear contribution to the group Communication Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking 8.1.5. Verbalises his/her opinion/messages. Competence 10: Advising Advises on the purchase and use of materials, equipment: 10.1.1. Understands the requests and practical requirements. 10.1.2. Advises on purchase of reagents based on product and sales conditions. Competence 11: Professional development Guides own competency development 11.1.3. Takes a critical look back (reflects) on their own actions and learning process; learns from his mistakes. In the context of a suitable case study.

See also assessment form below for the Advice Presentation LS4.

See form: Advice Presentation ± 30% Content (advice and teamwork), ± 40% Presentation; ± 30% Discussion. Pass mark: 55% is equivalent to 5.5

Code: LS4T-HBO Name:

Competence 9: Guiding/Supervising Meetings 9.1.1. Creates an agenda following a standard format, and uses this to lead a meeting independently.

See assessment form below ‘Agenda/Chairperson, level I’

2 signatures (=satisfactory) for ‘Agenda’ and

2 for ‘Leading PBL group’ on Competency card are required.

All criteria must be met to get 'Satisfactory'


72

Competency card Form: Oral In writing Individual Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 6: Reporting and presenting 6.1.2. Takes the minutes of meetings as described in product criteria minutes level 1.

See assessment form below ‘Meeting minutes, level I’

2 signatures (=satisfactory) on the competency card are required

Competence 6: Reporting and presenting 6.1.3. Is familiar with the international conventions of scientific and academic writing. 6.1.4. Presents research to audience with a similar background following the criteria of presentation techniques and answers questions.







makes well-structured and clear slides or other visual products Competence 8: Teamwork / communication 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking 8.1.5. Verbalises his/her opinion/messages.

See assessment form below ‘Theme presentation level I’

2 signatures (=satisfactory) on the competency card are required

Code: LS4T-St Name: Mini-internship Form: Individual Written Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 8: Internationalisation 8.1.7. Is aware of the international character of the profession. Competence 11: Professional development 11.1.2. Works on learning aims according to the PDP and collects evidence of competency. 11.1.4. Has general higher education study skills; self-motivated, has determination. 11.1.6. Is aware of the international market of the profession

Participation in the mini-internship.

Describing the experience in a report.

Participation in the workshop and completion of the task are both required for a satisfactory assessment.

Code: LS4T-FG2 LS4T-FG3 Name: LS4T-FG2: Performance

Competence 11: Professional development 11.1.2. Works on learning aims according to the PDP and collects evidence of competency. 11.1.3. Takes a critical look back (reflects) on their own actions and learning process; learns from his mistakes. 11.1.4. Has general higher education study skills; self-motivated, has

See assessment form below ‘Performance review, level I’ 3 performance interviews per year (start of academic year, end of semester 2, end of foundation year).

See assessment form below ‘Performance review, level I’ All criteria must be Satisfactory for an overall satisfactory grade.


73

review 2 LS4T-FG3: Performance review 3 Form: Oral Individual Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

determination.

Code: LS4T-POP Name: PDP Form: Individual Written Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 11: Professional development 11.1.1. Creates the PDP according to guidelines.

See assessment form below ‘PDP level I’ See assessment form below ‘PDP level I’ All criteria must be Satisfactory for an overall satisfactory grade.

Code: LS4T- LPO SCV Ch Name: Conflict management Form: Individual Written Oral Weighting: 0

Competence 8: Teamwork / communication 8.1.5 Verbalises his/her opinion/messages. 8.1.6 Shows initiative to actively solve conflicts.

Participation in the Conflict Management Workshop is compulsory.

Participation in the workshop and submission of the reflection assignment is required for a satisfactory grade.


74

Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory


75

Assessment Form LS4T-V Research Report Name:………………………………………………... Class: ………………. Date:....................



Number of points

Content

1.1.1. The research aim is described. 4

2.1.1.

Method

The principle of the methods

determining colony forming units 3

optical density measurement. 3

is described.

3.1.1., 3.1.2. Analysing data

The number of bacteria at different time points according to the method described in the workshop used for:



If points are not reliable, this is justified and they are not included in calculating the bacterial count.

3.1.1. A growth curve is drawn on the basis of the calculated number of bacteria that are derived from:


the optical density measurement 3

3.1.1. A logarithmic curve is drawn on the basis of the calculated number of bacteria that are derived from:


the optical density measurement 3

3.1.1., 3.1.2. The specific growth rate is determined base on the:


If measurements are not reliable, this is justified and they are not included in calculating the specific growth rate.


If measurements are not reliable, this is justified and they are not included in calculating the specific growth rate.

3.1.1., 3.1.2. The division time is calculated on the basis of:



If points are not reliable, this is justified and they are not included in calculating the division time.

The accuracy of the calculated division time is justified.

3.1.4. In the error analysis, the reliability and the accuracy of the results for the colony forming units are discussed



Proposals for an improved follow-up experiment are made. 2

3.1.3. A conclusion is drawn about the division time and growth rate of the bacterium. There is a comparison with the theoretical values of the division and growth rate.

5



k.o.

6.1.1. The report is clearly structured using the provided guidelines (page numbers, table of contents, bibliography)

3

6.1.1. The figures and tables are in accordance with the instructions provided in the workshop.

4


Grade (Number of points /6)


76

Feedback Assessor Name and Signature


77

Assessment form Advice Presentation LS4T-AP Name:………………………………………………... Class: ………………. Date:....................


Assessment criteria

Max Number of points

Number of points

8.1.2.

10.1.1, 10.1.2 11.1.3

Contents

States the aim of the research.

Gives a clear explanation of the methods

Discusses the advantages and disadvantages of each method and provides additional information in support of this.

Based on this, gives the client clear advice

Discusses the cooperation and division of tasks in the group

2 2 5

5

2

6.1.3.

Presentation

There is structure in the presentation (head-body-tail)

Makes well-structured and clear slides or other visual products:

applies correct spelling and grammar

Describes results so that the audience can understand them; uses for this clearly labelled pictures and tables

Speaks clearly and intelligibly

Stands upright and keeps hands relaxed

Makes eye contact with the audience


3 3 4

3 2 3 2

8.1.3, 8.1.4, 8.1.5

Discussion

Maintains eye contact with conversation partner

Allows others to finish speaking

Supports advice/own opinion clearly with well-justified arguments.

Is able to convince the client of the quality and reliability of the advice

2 2 5

5



Feedback



78

Assessment form Agenda/Chairperson Year 1 Name: ……………………………………………..……….. Class: ………………. Date: ..........……………….

unsatisfactory satisfactory

Competence 9.1.1: Creates an agenda following a standard format, and uses this to lead a meeting:

Agenda:

Type of meeting, date, time, place, attendees are listed.

Structure of the agenda is clear. (opening, notes, announcements, informative agenda points, open discussion, closing).

The agenda is distributed on time, according to agreements.

Meetings:

Introduces agenda points and works through the points in a structured manner.

Monitors the time.

The student gives structure to the meeting by adhering to to the main themes.

Summarises key points regularly.

Ensures information is clear by, if needed, asking questions

Gives everyone a chance to speak.

Summarize key points regularly and lists action points for the minutes.

Final assessment (for satisfactory, all components must also be satisfactory)

Feedback

Tutor Name and Signature


79

Assessment form Meeting Minutes Year 1

Name: ………………………………………….………….. Class: ………………. Date: ..........……………….

Competence 6.1.2. Takes the minutes of meetings as described in product criteria minutes level 1.


Components present: Attendees, date, place, time, chairperson and secretary.

Information is organised per agenda item.

Information is displayed in clear language.

Action list is added.

The agenda is distributed on time.


Feedback



80

Assessment form Presentation year 1 for Satisfactory / Not Satisfactory (tick off on competency card)

Name:………………………………………………... Class: ………………. Date: ..........……………….

Related to comp. / indicators

Assessment criteria

Unsatisfactory

satisfactory

Contents

not applicable.

The student gives the aim of the presentation.*

The information presented is of sufficient depth and generally correct in content.*

Presentation

The student provides a concise handout of the presentation. *

6.2.3.

There is structure in the presentation (head-body-tail) and the student gives an overview of the presentation at the beginning.*


- Applies correct spelling and grammar (more than 10 errors in the presentation results in an unsatisfactory grade)*;

- Describes results so that the listener can understand these; uses for this clearly labelled figures and tables

Speaks clearly and intelligibly*.



Discussion

6.2.3, There is interaction about the topic with the audience*

8.1.4 Allows others to finish speaking

8.1.5. Supports own opinion clearly.

Final assessment (Overall ‘satisfactory’ grade: All criteria indicated with * are satisfactory, and for the other criteria, at least 3/5 are satisfactory)

Feedback

Assessor Name and Signature


81

Assessment form PDP End Year 1

Name: ………………………………………………….. Class: ………………. Date: ..........……………….


Competence 11.2.1. Describes strengths and weaknesses:

The student describes his own strengths and weaknesses

Competences 11.1.1./11.2.2.: Creates the PDP according to guidelines and the personal strengths and weaknesses:

The student describes personal learning questions or aims.

The student makes a concrete action plan (what, with who, when, which activities) to achieve the aim.

The student describes desired results or products that are demonstrable.

Students mentions any foundation year courses that must be retaken.

The student uses correct spelling and sentence structure in the PDP.

The PDP is clearly structured.

Final assessment (for and overall satisfactory assessment, all individual components must be satisfactory)

Feedback



82


Name:………………………………………………………... Class: ………………. Date: ..........……………….

Competency indicator Assessment criterion Unsatisfactory Satisfactory

8.1.1. Observes the rules. Student meets agreements, is punctual, and prepared (e.g. DPF is in order).

11.1.2. Works on learning aims according to the PDP and collects evidence of competency.

The student can demonstrate that he has actively worked on the learning outcomes that are described in the PDP.

11.1.3. Takes a critical look back (reflects) on their own actions and learning process; learns from his mistakes.

The student methodically takes a critical look at his/her learning process, identifies what went well, and what didn’t go well, identifies the causes of these, and links it to his/her own actions. A plan for improvement in the future is formulated.

11.1.4. Has general higher education study skills: self-motivated, has determination.

The student shows a pro-active attitude and is motivated. He/she shows determination in his study.


Feedback



83

Course unit title Course unit AB4: Introduction to cutting edge techniques in the Life Sciences ECU AB4: Introduction to cutting edge techniques in the Life Sciences

Code AB4

1. Degree Biology and Medical Laboratory Research (joint degree), Life Science

2. Target group Full-time foundation year Life Sciences component Analytical Biosciences


professional tasks

Carrying out scientific research

4. Central

professional task

N/a

5. (Professional)

Products

Report (V)

Advice Presentation (AP)

6. Study credits,

study load

15 stp

420 SBU

7. Cohesion with

other educational

units

Builds on LS2a, LS2b and LS3 and prepares for the main phase, component Analytical

Biosciences.

To be able to continue with the regular main phase containing course 5ABC and 6ABC a

re-cap program is necessary to catch up with the missing theory.

8. Entry

requirements

regarding

(interim) exams


Technology or Nature and Health and participation in course unit 1 and 2abc

MBO diploma level 4 and/or participation in course unit 1, 2abc.

MLO transfer students.

Participation in course units LS3K, LS3T and LS3P

P: attendance at practicals is compulsory. IPV: presence at tutor lessons is compulsory.

9. General

description

In this educational unit, you will be acquainted with the underlying techniques and

technology that has driven 21st century life sciences to its current state. You will become

familiar with the character of physical laws that are exploited to visualize bio molecules

in a range of contemporary technologies.

Taught material through either lecture, workshop or expert class will provide an

overview of the breakthroughs and advances leading to such techniques as next

generation sequencing, fluorescent microscopy and mass spectrometry.

Research in this educational unit is focused on the development of a custom gene

chip/diagnostic macro-array or micro-array, to explore gene expression within an

experimental system. Students will develop an appreciation of the physics, technology

and data generated in such an approach. Regarding the competence "research analysis",

a report is created containing an analysis of experimental data.

This course is taught in English. All assessment is carried out in English.

10. Competences Design of experimental set up

Experimenting

Results analysis

Quality control



Methodology

Teamwork

Advising


11. Assessment

criteria

See assessment Programme for description of exams, assessment criteria and indicators.


84

12. Assessment Modular examinations AB4-V Report

AB4-T Theme test

AB4-K Knowledge test (K)

AB4-P Practical Assessment

AB4-AP Advice Presentation

AB4-IPV IPS

AB4-HBO HBO Competency card AB4-St Mini-placement AB4-PDP PDP AB4-FG2 Performance review 2

AB4-FG3 Performance review 3

AB4-LPO SCV-ch Conflict management

Weighting Final grade: (2*T + 2*K+ 2*P + AP + V)/8

Compensation

possibilities

-


examination

IPS, performance review, workshops, professional products

and competency card must be ticked off with ' Satisfactory '

and assessment grades/professional products ≥ 5.5.

Frequency (modular)

examinations

Teaching period 4, resit end period 4

13. Compulsory

literature

#OnderwijsOnline

14. Recommended

literature

-

15. Software -

16. Other material In this unit, multimedia tools are used to support the teaching, such as Powerpoint,

video and social media.



Modern analytical

techniques and their

detection strategies

Historical perspective of 45 years of modern biological

analytical techniques and their contribution to advancing

knowledge and understanding of life science.

Fundamental physical laws exploited in techniques such as

fluorescent probes (microscopy/microarray/gene-chip);

Mass spectrometry; GC/HLPC chromatography;

voltage/photonic detection. These should include examples

of the kind of raw/processed data produced and how it

relates to experimentation.

Scope/scale of experiment produced leading up to the big

data approach tackled by bioinformatics approaches.

Working methods: lecture/ICT blended learning

Supporting subject

Biomolecule detection

Physical chemistry

Spectroscopy

Material should be taught in an applied sense, or relatable

to technique(s).

Working methods: lecture with demonstrations

Workshop

Working safely with

biological agents

Risk and safety, risk analysis

Pathogens, physical containment, biological containment

Risk classes and containment levels


85

Epidemiology of lab infections

GMT, SMT and in practice

Working with lasers; potential carcinogens/teratogens.

Procedure : workshop

Supporting subject

Practical work

Learning the techniques practical aspects that lead to the

building a custom array gene chip for detecting levels of

gene expression in an experimental system.

Such techniques include but are not limited to; Preparation

of labelled cDNA RT-PCR; labelling with fluorescent dyes;

DNA quantification; Probe (including +ve and –ve control)

production and spotting/blotting to slide/microtitre plate;

UV-crosslinking; Hybridization of target to probe; detection

of fluorescence; transformation and or normalisation of

data.


Workshop

Analysis of results

Interpretation of research results

Drawing the correct conclusions from results

Analysis with appropriate statistics and visualization (R

scripts/plotting)

Placing results in context of data generated from

affymetrix/abi biochip (scale/quality).

Extracting and processing (i.e. normalization) essential

information from results files in a reproducible manner (R

scripting)

Data management, versioning and archiving

Procedure : Workshops (IT suites) potentially scheduled as

Skype meeting with UoD

Workshop

Conflict management

Conflict management

Procedure: workshop


hours


10 practical hours/week, 8 lecture hours/week, excluding 144 lesson hours/period = 108

hours self-study

Planned time for self-study :312 hours

Total: 420

20. Teaching period Term 4

21. Maximum

number of

participants

Maximum number possible in the Analytical Biosciences component in Dundee: 10

students


86

Assessment programme course unit AB4: Introduction to cutting edge techniques in the Life Sciences (AB4)

Carrying out scientific research Modular examinations Indicators / Assessment criteria Weighting/Passing grade Code: AB4-P Name: Practical Form: Practical Weighting: 2 Assessment: Grade Lower limit: 5.5

Competence 1: Design 1.1.4. Formulates a corresponding hypothesis based on a given research question. Competence 2: Experimenting 2.1.1. Reads the lab protocols, understands them and understands the theoretical background of the basic steps. 2.1.2. Performs calculations prior to beginning lab work. 2.1.4. Conducts experiments accurately according to the lab protocol. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.3. Draws conclusions regarding the research question (if possible). 3.1.4. Discusses the execution and experimental results. Competence 4: Quality Control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly Competence 5: Management and administration 5.1.1. Labels the chemicals and samples and stores these in prescribed manner. 5.1.2. Leaves the work space cleaned and tidied. 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6: Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:




Describes results so that the reader understands these; uses for this clearly labelled illustrations and tables;

6.1.3 Is familiar with the international conventions of scientific and academic writing. Competency 7: Working in a planned and project-based manner 7.1.3. Executes work according to a plan. Competence 11: Professional development 11.1.4. Has general higher education study skills: self-motivated, has determination.

Assessment Practical Level 1 (See assessment form Assessment form Practical with lab journal, Level I, Term 4).

Average products = (GMT, SMT Conclusion + 4*assessment practical activities)/5. All individual marks must be ≥ 5.5.


87

In the context of:

Working with DNA

Labelling DNA

Hybridizing DNA

Detecting labelled DNA

Measuring fluorescence.

Crosslinking DNA

Gathering and processing data out of sophisticated lab equipment

Code: AB4-V Name: Research report Form: In writing Group Weighting: 1 Assessment: Grade Lower limit: 5.5

Competence 1 Designing 1.1.1. Independently identifies relevant background information required to answer the research question. Competence 2: Experimenting 2.1.1. Reads the lab protocols, understands them and understands the theoretical background of the basic steps. Competence 3: Results analysis Data processing 3.1.1. Analyses the results appropriately according to the prescribed methods. Validation 3.1.2. Assesses the usability of the results based on of accuracy and reliability. Conclusions and discussion 3.1.3. Draws conclusions regarding the research question (if possible). Competency 5 Management and administration 5.1.3. Manages and archives data in lab journal (aim, experiment description, changes, results, conclusion) and if applicable, in other ways. Competence 6 Reporting and presenting 6.1.1. Reports on own research as defined in a form as described in the criteria for lab journal / lab report level 1:




describes results so that the reader understands these; uses for this clearly labelled illustrations and tables;

Competence 10: Advising Advises on the purchase and use of materials, equipment: 10.1.1. Understands the requests and practical requirements. 10.1.2. Advises on purchase of reagents based on product and sales. In the context of:

Development of a prototype microarray.

Determination of a successful DNA labelling, annealing and

See assessment form below ‘research report` . Text The report is structured according to the provided points and written with correct spelling and grammar. The description of tables and figures are according to prescribed standards.

See assessment form below ‘research report` 80% content. 20% text. 55% of the maximum amount of points is 5.5 .


88

detection.

Identification of putative transcripts in a tissue isolate/extraction.

Code: AB4-IPV Name: IPS Form: Oral Individual Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 7: Working in a planned and project-based manner 7.1.3. Executes work according to a plan. Competence 8: Cooperation Functioning in a group 8.1.1. Observes the rules. 8.1.2. Makes a clear contribution to the group Communication Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking. 8.1.5. Verbalises his/her opinion/messages. 8.1.6. Is open to, and offers feedback. Internationalization 8.1.7. Is aware of the international character of the professional community Competence 11: Professional development 11.1.4. Has general higher education study skills: self-motivated, has determination.

The student:

has prepared for the meeting by completing the assignment to be discussed, and also completed the required reading for the following assignment to be discussed (k.o.).

is able to show assignment products to the tutor (in writing or in presentation); in all assignments all required aspects are complete (k.o.);






Group members evaluate the effort and commitment of the student (IRIS).


Code: AB4-T Name: Theme test Form: In writing Individual Weighting: 2 Assessment: Grade Lower limit: 5.5

Competence 2: Experimenting 2.1.1. Reads the lab protocols, understands them and understands the theoretical background of the basic steps. 2.1.2. Performs calculations prior to beginning lab work. Competence 3: Results analysis 3.1.1. Analyses the results appropriately according to the prescribed methods. 3.1.2. Assesses the usability of the results based on of accuracy and reliability. 3.1.3. Draws conclusions regarding the research question (if possible). Competence 4: Quality Control 4.1.1. Is aware of the safety (work) and environment rules and works accordingly 4.1.3. Uses controls, the results of which are used to assess the reliability of the results. In the context of: Using UV spectroscopy and other detection methods to analyze biomolecules using protoype -omic devices.

Theory The student:

can give an account/summary of the development of modern bio analytical techniques with reference to advances in technology and understanding;

understands the theoretical background of PCR and variants;

understands the hybridization of DNA to DNA as a method for detecting gene transcripts;

understands related crosslinker and immobilization chemistry, and can determine an appropriate reaction for the production of a microarrays;

is able to apply knowledge of different characteristics of fluorophores to develop a simple assay.

Practical Design/Experiment The student:

understands technology, strategies and methods used in the research topic;

knows the physical and chemical underlying principles of the project;

Exam questions are divided on the following subjects: Theory (approx. 30%) Practical (approx. 70%)


89

understands the purpose of positive and negative controls in the experiment.

Results

can determine the reliability or prototype microarray;

can draw correct conclusions from experimental data.

Code: AB4-K Name: Detection of Biomolecules Form: In writing Multiple choice Individual Weighting: 2 Assessment: Grade Lower limit: 5.5

Historical perspective of 45 years of modern biological analytical techniques and their contribution to advancing knowledge and understanding of life science. General introduction in biomolecules and techniques used in genomics, proteomics, metabolomics and transcriptomics; such as NMR, Mass spectrometry, flow cytometry, sequencing, chromatography and microarray. Physical organic chemistry leading to knowledge of functional groups. Biomolecular crosslinking and immobilization techniques. Chemistry leading to photo reactive group (i.e Azides and diazirines). Biomolecular labelling, and conjugation. Use of a label as a proxy for detection; Hybridization, annealing and co-valent bonding. Basic principles of UV Spectrophotometry; Properties of fluorescent molecules, such as their molecular structure; energy absorption and photon emission; Stoke’s shift; molecular excitation; Quenching; Beer’s law; E=hv; FRET; Photoelectric effect, photomultipliers and photodiodes in light detection.

Spectroscopy The student:

knows Beer’s law and is able to calculate with it and apply it in calibration curves;

can explain what makes a component fluorescent;

can explain the difference between excitation and emission;

can convert wavelengths to energy and vice versa;

can explain the principle of measuring using spectroscopy;

can explain the photoelectric effect and how a photodiode functions;

knows the principle of FRET and FLIM;

knows how equipment works;

knows the difference between luminescence and fluorescence;

knows how to interpret Jablonski diagrams;

describe and apply quantum yields.

Physical organic chemistry: The student:

can identify the products of several reactions (for example condensation polymerization reactions) that relate to cross-link and functional group chemistry;

has a basic understanding of molecular orbital theory;

has basic understanding of corresponding organic chemistry.

60% questions about spectroscopy , 40% questions about physical chemistry Pass mark: 70% correctly answered is equivalent to a satisfactory (5.5).

Code: AB4-AP Name: AP: Advice Presentation Form: Oral Group

Competence 6: Reporting and presenting 6.1.3. presents research to an audience with a similar background according to the criteria of presentation techniques and answers questions:


describes results so that the reader can understand these; uses for this clearly labelled pictures and tables;


speaks clearly and coherently;

See form: Advice Presentation See form: Advice Presentation ± 30% (14 points) Content (advice and team work), ± 40% (21 points) Presentation; ± 30% (15 points) discussion . Pass mark: 27.5 points equivalent for a satisfactory assessment (5.5). Participation in all workshops is required


90

Weighting: 1 Assessment: Grade Lower limit: 5.5


makes eye contact with the audience;

makes well-structured and clear slides or other visual products Competence 8: Cooperation / Functioning in a group 8.1.2. Makes a clear contribution to the group Communication Communicates his task to fellow students and lecturer according to the basic rules of communication; if needed, supervised by the lecturer. 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking. 8.1.5. Verbalises his/her opinion/messages. Competence 10: Advising Advises on the purchase and use of materials, equipment: 10.1.1. Understands the requests and practical requirements. 10.1.2. Advises on purchase of reagents based on product and sales. Competence 11: Professional development Shapes their own competence development 11.1.3. Takes a critical look back (reflects) on their own actions and learning process; learns from his mistakes. In the context of: Acquiring microbiological media and cytological reagents

for satisfactory assessment of ‘Participation’.

Code: LS4T-HBO Name: Competency card Form: Oral Written Individual Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 9: Coaching / supervising Meetings 9.1.1. Creates an agenda following a standard format, and uses this to lead a meeting independently.

See assessment form below ‘Agenda/Chairperson, level I’

2 signatures (=satisfactory) for ‘Agenda’ and 2 for ‘Leading PBL group’ on Competency card are required.

Competence 6: Reporting and presenting 6.1.2. Takes the minutes of meetings as described in product criteria minutes level 1.

See assessment form below ‘Meeting minutes, level I’ 2 signatures (=satisfactory) on the competency card are required

Competence 6: Reporting and presenting 6.1.3. Is familiar with the international conventions of scientific and academic writing. 6.1.4. Presents research to audience with a similar background following the criteria of presentation techniques and answers questions.




See assessment form below ‘Theme presentation level I’ 2 signatures (=satisfactory) on the competency card are required


91

speaks clearly and coherently;



makes well-structured and clear slides or other visual products Competence 8: Cooperation / communication 8.1.3. Maintains eye contact with conversation partner. 8.1.4. Allows others to finish speaking. 8.1.5. Verbalises his/her opinion/messages.

Code: LS4T-St Name: Mini-internship Form: Individual Written Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 8: Internationalization 8.1.7. Is aware of the international character of the profession. Competence 11: Professional development 11.1.2. Works on learning aims according to the PDP and collects evidence of competency. 11.1.4. Has general higher education study skills: self-motivated, is determined. 11.1.6. Is aware of the international market of the profession

Participation in the mini-internship. Describing the experience in a report.

Participation in the workshop and completion of the task are both required for a satisfactory assessment.

Code: LS4T-FG2 LS4T-FG3 Name: LS4T-FG2: Performance review 2 LS4T-FG3: Performance review 3 Form: Individual Oral Weighting: 0 Assessment: Satisfactory/unsatisfactory

Competence 11: Professional development 11.1.2. Works on learning aims according to the PDP and collects evidence of competency. 11.1.3. Takes a critical look back (reflects) on their own actions and learning process; learns from his mistakes. 11.1.4. Has general higher education study skills: self-motivated, is determined.

See assessment form below ‘Performance review, level I’ 3 performance reviews per year (start of academic year, end of semester 2, end of foundation year).

See assessment form below ‘Performance review, level I’ All criteria must be Satisfactory for an overall satisfactory grade.


92

Lower limit: Satisfactory

Code: LS4T-POP Name: PDP Form: Individual Written Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 11: Professional development 11.1.1. Creates the PDP according to guidelines.

See assessment form below ‘PDP level I’ See assessment form below ‘PDP level I’ All criteria must be Satisfactory for an overall satisfactory grade.

Code: LS4T- LPO SCV Ch Name: Conflict management Form: Individual Written/Oral Weighting: 0 Assessment: Satisfactory/unsatisfactory Lower limit: Satisfactory

Competence 8: Cooperation / communication 8.1.5 Verbalises his/her opinion/messages. 8.1.6 Shows initiative to actively solve conflicts.

Participation in the Conflict Management Workshop is compulsory.

Participation in the workshop and submission of the reflection assignment is required for a satisfactory grade.


93

Assessment form GMT, SMT conclusion AB4 Name: ………………………………………………… Class: ………………….. Date: ………………………… Related to comp./ indicators


Number of points

Contents

3.1.1. The results of the 6 GMT experiments are concisely described in such a way that it is clear to the reader how the experiment was executed and what the results were.

10

3.1.3, 3.1.4 The correct conclusions are made from the results regarding the GMT, SMT guidelines:

effect of soap and Sterillium on the transient flora and resident flora (washing hands after work)

5

effect of tissue with ethanol on contaminated work surface (disinfection after work)

5

presence of bacteria on surfaces and the effect of disinfection (disinfection of work surfaces)

5

effect of hot inoculating loop (letting loop cool after heating to glowing point)

5

number of infected students after 2 rounds of shaking hands (wash hands after practical work)

5

mechanism of disinfectants on the tested bacteria (disinfection of surfaces)

5

6.1.1. The terms GMT, SMT, transient flora and resident flora are used in the right manner in the conclusion.

5



5

6.1.1. The conclusion is no longer than 1 A4 (typed). Satisfactory / Not Satisfactory


50


Feedback



94

Assessment form Lab Journal AB4P

Name:……………………................................... Date:……………………… Class:…………………….





incorrect -0-


-2-


-3-


-4-


Hypothesis missing

-0-


-2-


-3-


-4-

5.1.3.



-0-

Materials and methods are clear, some pipetting schemes are missing or changes are not

recorded. -3-

Materials and methods are often complete and correct

-4-


-6-


Questions are not answered, or often incorrectly

answered -0-


-2-


-3-


-4-



-0-

Results are complete and clear but the analysis sometimes

contains errors -2-

Results are complete and clear and the analysis is often

correct -3-


always correct -4-


Results are incomplete or often do not agree with the

expectations -0-

Results are sometimes not in agreement with the

expectations -2-


-3-


expectations -4-

2.1.1. 3.1.4.

In the discussion section of the lab journal, the student explains the results and makes statements about the accuracy and reliability.

Results are not explained

and there are no statements


reliability

-0-


and there are statements


reliability

-5-


and there are correct

statements about accuracy and

reliability

-6-


explained and there are clear

and correct statements about


-8-



-0-


-5-


-6-


-8-

5.1.1. 5.1.3.


Not Satisfactory Satisfactory


95

6.1.1. The lab journal is well-structured and records the required preparations for the practical work.



-0-

Lab journal is well organised and sometimes records the

required preparations.

-5-

Lab journal is well organised and records all required

preparations

-6-

Lab journal is exceptionally orderly and the preparations

are recorded in detail and in a timely fashion.

-8-


Final assessment (total number of points/5 AND all are satisfactory)

Feedback

Name signature assessor


96

Assessment form Practical with lab journal, Level I, Term 4

Name: ……………………………………………….………………. Class: ……………………………………………………………………. Date: …………………………………………………………………….


Assessment criteria Unsatisfactory Satisfactory Good Excellent Number points

LAB JOURNAL


1 or more of the components is missing

or incorrect -0-

All components are present yet contain

some errors -2-


-3-

All components are present and always

correct -3-


Hypothesis missing

-0-


-2-


-3-


-4-

2.1.2. The student performs calculations prior to beginning lab work. Preliminary calculations are missing

-0-


mistakes -1-


-2-

Preliminary calculations are always

correct -3-


Questions are not answered, or often incorrectly answered

-0-


incorrectly -1-

Questions are often answered correctly

-2-

Questions are always answered

correctly -2-



-0-

Results are complete and clear but the

analysis sometimes contains errors

-2-


often correct

-3-

Results are complete and clear and the analysis is always

correct -4-

2.1.4. The results agree with the theoretical expectations. Results are incomplete or often do not agree with the expectations

-0-

Results sometimes do not agree with the

expectations -2-


-3-

Results always agree with the expectations

-4-

3.1.2.

3.1.4.

In the discussion section of the lab journal, the student explains the

results and makes statements about the accuracy and reliability.

Results are not


no statements made

about accuracy and

reliability

-0-

Results are partly




-6-

Results are partly




-8-



clear and correct

statements about


-10-


97

3.1.3. The student draws the right conclusion based on the results. Conclusions are absent or often incorrect

-0-


-6-


-8-


-10-

5.1.1. 5.1.3.


Not Satisfactory

6.1.1. The lab journal is well-structured. Lab journal is very disorganised

-0-


-6-


-8-


-10-

LAB ACTIVITIES

4.1.1. The student works according to the health and safety regulations,

Not Satisfactory

5.1.2. The student cleans the work space and leaves it clean for others. Often does not tidy away the materials used

-0-

Sometimes tidies away the materials used

-4-

Always tidies away the materials used

-6-

Always tidies away the materials used and

regularly contributes to tidying the lab.

-10-



is working on -0-


he/she is on -6-


-8-

is always able to explain - which step is

being done -10-

2.1.5. 7.1.3.


Often runs late -0-

Sometimes runs late -6-

Never runs late -8-

Is very efficient -10-



attitude

-0-


attitude

-6-


-8-

Always has a satisfactory

work attitude and helps others

-10-

Total number of points:

Final assessment (Total number points/9 and every component at least satisfactory)

Feedback

Assessor name and signature


98

Assessment form Advice Presentation AB4

Name: ………………………………… Class: ………………….. Date: …………………………



Number of points

8.1.2.

10.1.1, 10.1.2 11.1.3

Content

Describes the request from the client with the related criteria.

Discusses the technologies available to address the biological questions.

Based on this, gives the client clear advice regarding

costs/development time/data quality and type.

Discusses the cooperation and division of tasks in the group.

50

6.1.3.

Presentation

There is structure in the presentation (head-body-tail)


applies correct spelling and grammar

Describes results so that the reader understands these; uses for this clearly labelled illustrations and tables;

Speaks clearly and coherently;

Stands upright and keeps hands relaxed



30

8.1.3, 8.1.4, 8.1.5

Discussion

Maintains eye contact with conversation partner.

Allows others to finish speaking

Supports advice/own opinion clearly with well-justified arguments.

Is able to convince the client of the quality and reliability of the advice

20



Feedback

Name and signature assessor


99

Assessment form ‘Research report AB4’

Name: ………………………………… Class: ………………….. Date: …………………………



Number of points

Content 1.1.1. The research aim is described. 10 2.1.1. Method 10

The principle of the methods are described. 3.1.1., 3.1.2. Analyzing data 20

Data is interpreted in a robust fashion

Analysis is conducted with reference to appropriate controls

Normalization or transformation has been performed if necessary 3.1.1. Data visualization

Student selects an appropriate plot type to visualise the analysis 10 3.1.4. In the error analysis, the reliability and the accuracy of the results are

discussed.

Proposals for an improved follow-up experiment are made. 10 3.1.3. A conclusion is drawn and there is a comparison with the theoretical values.

10

Structure / Layout / Writing 6.1.1. The report is written with correct spelling and grammar.

More than 5 errors per page means that the report will not be assessed. k.o.


100

6.1.1. The report is clearly structured using the provided guidelines (page numbers, table of contents, bibliography)

15

6.1.1. The figures and tables are in accordance with the instructions provided in the workshop.

15

Total number of points:

Grade (Number of points /10) Feedback

Assessor name and signature


101

Assessment form calendar/Chairperson Year 1 Name: Class: …..……….. Date:....................

Not Satisfactory Satisfactory

Competence 9.1.1: Creates an agenda following a standard format, and uses this to lead a meeting independently.

Agenda:

Type of meeting, date, time, place, attendees are listed.

Structure of the agenda is clear. (opening, notes, announcements, informative agenda points, open discussion, closing).

The agenda is distributed on time, according to agreements.

Meetings:

Introduces agenda points and works through the points in a structured manner.

Monitors the time.

The student gives structure to the meeting by adhering to the main themes.

Summarises key points regularly.

Ensures information is clear by, if needed, asking questions

Gives everyone a chance to speak.

Summarize key points regularly and lists action points for the minutes.


Feedback



102

Assessment form Meeting Minutes Year 1

Name: ………………………………………….…………….. Class: ………………. Date: ……………….

Competence 6.1.2. Takes the minutes of meetings as described in product criteria minutes level 1.

not satisfactory satisfactory

Components present: Attendees, date, place, time, chairperson and secretary.

Information is organised per agenda item.

Information is displayed in clear language.

Action list is added.

The agenda is distributed on time.


Feedback


Opleidingsstatuut Instituut Toegepaste BiECUtenschappen en Chemie Deel 3 Opleiding Biologie en Medisch Laboratoriumonderzoek Beschrijving van het onderwijs 2017-2018 Chapter 2: Course Units and Integral Assessments of the Foundation Year

103

Assessment form Presentation year 1 for Satisfactory / Not Satisfactory (tick off on competency card)

Name:………………….……………………………….. Class: ………………. Date: ……………….

Related to comp. / indicators

Assessment criteria

Not Satisfacto

ry

satisfactory

Contents

not applicable.

The student gives the aim of the presentation.*

The information presented is of sufficient depth and generally correct in content.*

Presentation

The student provides a concise handout of the presentation. *

6.2.3.

There is structure in the presentation (head-body-tail) and the student gives an overview of the presentation at the beginning.*


- applies correct spelling and grammar (more than 10 errors in the presentation results in an unsatisfactory grade)*;

- describes results so that the listener can understand these; uses for this clearly labelled figures and tables

Speaks clearly and intelligibly*.



Discussion

6.2.3, There is interaction about the topic with the audience*

8.1.4 Allows others to finish speaking.

8.1.5. Supports own opinion clearly.

Final assessment (Overall ‘satisfactory’ grade: All criteria indicated with * are satisfactory, and for the other criteria, at least 3/5 are satisfactory)

Feedback

Name and Signature Assessor


104

Assessment form PDP End Year 1

Name: ………………………………………….Class: ………………. Date:……………….

not satisfactory satisfactory

Competence 11.2.1. Describes strengths and weaknesses:

The student describes his own strengths and weaknesses

Competences 11.1.1./11.2.2.: Creates the PDP according to guidelines and the personal strengths and weaknesses:

The student describes personal learning questions or aims.

The student makes a concrete action plan (what, with who, when, which activities) to achieve the aim.

The student describes desired results or products that are demonstrable.

Students mentions any foundation year courses that must be retaken.

The student uses correct spelling and sentence structure in the PDP.

The PDP is clearly structured.


Feedback



105


Name: ………………………………………………………... Class: …..……….. Date:....................

Competency indicator Assessment criteria Not Satisfactory Satisfactory

8.1.1. Observes the rules. Student meets agreements, is punctual, and prepared (e.g. DPF is in order).

11.1.2. Works on learning aims according to the PDP and collects evidence of competency.

The student can demonstrate that he has actively worked on the learning outcomes that are described in the PDP.

11.1.3. Takes a critical look back (reflects) on their own actions and learning process; learns from his mistakes.

The student methodically takes a critical look at his/her learning process, identifies what went well, and what didn’t go well, identifies the causes of these, and links it to his/her own actions. A plan for improvement in the future is formulated.

11.1.4. Has general higher education study skills: self-motivated, is determined.

The student shows a pro-active attitude and is motivated. He/she shows determination in his study.


Feedback



106

Integral Assessment Foundation Year

Integral assessment title Integral exam foundation year


2. Target group Full-time foundation year BML, Life Sciences students, also from the

accelerated pre-university pathway (level 1).

3. Professional tasks Carrying out life science research

4. (Professional) products See ECU1, ECU2a, ECU2b, ECU2c, ECU3K, ECU3T, ECU3P, ECU4K,

ECU4T, ECU4P and ECU AB4

5. Study credits and/or

corresponding with regular

examinations

No study credits or examinations are linked to the integral test.

During an examination meeting, the Examination Board determines

whether the student has reached Level 1 after which a positive

study advice is given.

6. Cohesion with other integral

exams and preliminary

examinations

The integral test of the foundation year reviews whether the

student has reached level 1.

7. Prerequisites

All course units from the foundation year have been adequately

completed or there is an exemption granted for one or more course

units.

ECU3K, ECU3T, ECU3P, ECU4K, ECU4T, ECU4P: each 5 stp

ECU1, ECU2a, ECU2b, ECU2c: each 7.5 stp

ECU AB4 15 stp

Total 60 stp

8. General description The integral test consists of an examination to be carried out by the

Examination Board during the foundation year examination

meeting (July, August and on request in January). The Examination

Board investigates whether all course units of the foundation year

(total 60 stp) are adequately completed or exemption has been

granted for one or more course units.

9. Competence

For carrying out the professional task the following competences

are developed at level 1:

1. Designing an experimental plan

2. Experiment

3. Results analysis

4. Quality control

5. Management and administration

6. Reporting and presenting

7. Planning and project-based working

8. Co-operation in a team

9. Guiding/Supervising

10. Advising

11. Professional development

These competences are assessed several times in different

combinations through modular exams within the different course

units.

In part 1 of this Degree Charter, it is specified: For the professional

task “Carrying out scientific research”, all competences are

applicable.

10. Assessment criteria In the examination programme (Appendix to course unit

descriptions in part 3 of this Degree Charter) it is stated per

modular examination, the competences which are assessed and the


107

assessment criteria that apply.

11. Integral test characteristics and

forms

not applicable.

12. Obligatory and recommended

material

not applicable.

13. Teaching period not applicable.

Documents

Degree Charter - Hogeschool van Arnhem en Nijmegen · 2017-12-06 · Degree Charter For the Bachelor of Life Sciences Degree Programme ... Graphs and trendlines ... MAC-value, LD50-value,