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8/2/2019 Definition of Death
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When is dead?
The definition of death and its
implication for organ
transplantation
Cristina Gavrilovici, MD, MA, PhD
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Empirical and conceptual issues
Statutory definition of death: Uniform
determination of death act: an individual
who has sustained either
(1) irreversible cessation of circulation and
respiratory function or
(2) irreversible cessation of all functions ofthe entire brain, including the brain stem
is dead
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Empirical and conceptual issues
Death = natural event or process
the two notions approach:
the patient as person the person as body
there are dead bodies but no dead persons
how do we decide whether a body has ceased to
function ?
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Irreversibility
UPMC protocol: legally dead after 2 minutes of
pulseless apnea, unresponsivenes to verbal
stimulus, EKG
the moral questions:
whether the withdrawal of life support and subsequent
removal of organs are morally permissible
killing vs letting die
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Irreversibility
UPMC protocol: irreversible cesation of
cardiopulmonary function (legally dead after 2minutes of pulseless apnea, unresponsivenes to verbal
stimulus, EKG ()
the moral questions:
whether the withdrawal of life support and subsequent
removal of organs are morally permissible
killing vs letting die
the empirical question:
how much time after cardiopulmonary function is lost one
must wait to ensure that spontaneous recovery will not occur?
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Irreversibility
David Cole: central to UPMC protocol is
irreversible concept, that is dangerously
ambiguous:
irreversible by whom? When? Under what circumstances?
The UPMC protocol involves a totally implausible and weak
construct of what is for a loss of function to be irreversible
central to UPMC protocol is the absence of auto-resuscitation
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Irreversibility
Tom Tomlison: a critique of Cole:
irreversibility is a requirement that arises only at the
level of the criteria for the determination of death rather
than at the level of the concept of death. Why would anyone think that the determination of death
should be a determination of the irreversible?
A significant important translation of irreversible in
the criteria for determining death is the possibility of
reversal is not ethically significant.
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Irreversibility
Lynn and Cranford: four possible times of
death: T1: when critical function is lost
T2: when the critical function is observed to be lost
T3: when the function is irreversible lost
T4: when the function is demonstrated to be irrversible lost
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Public ambivalence and confusion
Acceptance in great part of the brain death
criteria because it was seen by the public
as a defense against the invasiveindignities of technological medicine.
The number of minutes needed to declaredeath might be ignored
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Public ambivalence and confusion
Trust in physicians and health care system
is often a problem in minorities
communities
fear of exploitation of innocent victims by
medical scientists
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Recommendations
1. When stipulating how long one must wait after
the cessation of circulatory function to declare
death, protocols should explicitly explain theempirical and philosophical grounds for their
position
2. If one holds the weakest position of
irreversibility, data will be helpful to reassure
skeptics that autoresuscitation will not occur.
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Recommendations
3. Transplant community should take seriously the
need for data based justifications for pushing the
time of death closer and closer to whencirculatory function is lost.
4. There should be organ procurementorganisations functioning as a regional engine
for opinion and practice change
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Recommendations
5. NHBD policies should be uniform with the
regards to the declaration of death
6. Institutional protocols should be developed with
community involvement and input.
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Recommendations and conclusion
Death is both a biologically based and socially
constructed notion about which there is little
prospect for social consensus