Dangerous Dangerous GrainsGrains

Kevin Logan, MDKevin Logan, MD

September 15, 2012September 15, 2012Groundwork ConferenceGroundwork Conference

8499 Fishers Center Drive Fishers, IN 46038 317-568-8499 Fishers Center Drive Fishers, IN 46038 317-568-43254325

office@loganmd.comoffice@loganmd.com www.loganmd.comwww.loganmd.com

Weston A. PriceWeston A. Price

TimelineTimeline

The birth of agriculture began in the Middle The birth of agriculture began in the Middle East with wheat first being cultivated in SyriaEast with wheat first being cultivated in Syria

Toxic in its raw form thus fermenting, soaking Toxic in its raw form thus fermenting, soaking and cooking increased digestibilityand cooking increased digestibility

Modern Agriculture Changes The Grass For Modern Agriculture Changes The Grass For Increased ProductivityIncreased Productivity

Larger seedsLarger seeds Whole “ears” of kernelsWhole “ears” of kernels

Ease of extraction of seedsEase of extraction of seeds

MonocultureMonoculture Mineral depletionMineral depletion Sterilization of soil based organisms Sterilization of soil based organisms

through the application of pesticides through the application of pesticides & anhydrous ammonia& anhydrous ammonia

Introduction of GMO’sIntroduction of GMO’s

Are Grain Based Diets Are Grain Based Diets Healthy?Healthy?

They are the cause of a host of nutritional They are the cause of a host of nutritional deficienciesdeficiencies

Iron - the most common mineral deficiency Iron - the most common mineral deficiency in the worldin the world

Vitamin A – important for epithelial repair Vitamin A – important for epithelial repair and prevention of night blindnessand prevention of night blindness

Zinc - which is critical for immune function, Zinc - which is critical for immune function, antiviral effects and is anti-inflammatoryantiviral effects and is anti-inflammatory

Magnesium – important for energy Magnesium – important for energy metabolism and cardiovascular healthmetabolism and cardiovascular health

Modern Diseases Associated Modern Diseases Associated with Grain Consumptionwith Grain Consumption

Corn – causes pellagra from depletion of B3 Corn – causes pellagra from depletion of B3 (Niacin) & tryptophan production(Niacin) & tryptophan production

Rice – causes beriberi due to B1 (thiamin) Rice – causes beriberi due to B1 (thiamin) deficiency, which caused thousands of deficiency, which caused thousands of deaths in Japan in the 20’sdeaths in Japan in the 20’s

Processed Wheat – caused deficiency of B1, Processed Wheat – caused deficiency of B1, B2, B3 and iron which are now fortified, but B2, B3 and iron which are now fortified, but still deficient in Ca, Mg, K, Zn, Cu, Fe, Mn, still deficient in Ca, Mg, K, Zn, Cu, Fe, Mn, Cr, MoCr, Mo

Whole Wheat – deficient in vitamin A, Whole Wheat – deficient in vitamin A, vitamin C, beta carotene and B12vitamin C, beta carotene and B12

Millet – cause goiter formation and impairs Millet – cause goiter formation and impairs iodine uptakeiodine uptake

EXORPHINS!EXORPHINS!

Whole Grains: Better for Us Than Whole Grains: Better for Us Than Processed GrainsProcessed Grains

1 cup whole wheat pasta = 37 gm of carbs 1 cup whole wheat pasta = 37 gm of carbs

-5 gm of fiber for a net of 32 carbs-5 gm of fiber for a net of 32 carbs 1 cup processed wheat pasta = 38 gm of 1 cup processed wheat pasta = 38 gm of

carbscarbs All grains contribute to the elevation of All grains contribute to the elevation of

blood sugar, insulin levels and risk of blood sugar, insulin levels and risk of metabolic syndrome/diabetesmetabolic syndrome/diabetes

What is the Truth About Phytic What is the Truth About Phytic Acid?Acid?

Friend or Foe? Friend or Foe? Non - ruminants lack Non - ruminants lack

phytase and cannot phytase and cannot digest this compounddigest this compound

Inhibits digestive Inhibits digestive enzymes including enzymes including amylase and glucosidaseamylase and glucosidase

Inhibits pepsin and Inhibits pepsin and trypsintrypsin

Inhibits nutrient uptake Inhibits nutrient uptake in the small intestinein the small intestine

Chelates Ca, Mg, Fe, Zn, Chelates Ca, Mg, Fe, Zn, NiacinNiacin

Phytic Acid containing Phytic Acid containing foodsfoods

Brazil nuts 1719Brazil nuts 1719Cocoa powder 1684-1796Cocoa powder 1684-1796Brown rice 12509Brown rice 12509Polished Rice 11.5 -66Polished Rice 11.5 -66Oat flakes 1174Oat flakes 1174Almond 1138 – 1400Almond 1138 – 1400Walnut 982Walnut 982Peanut roasted 952Peanut roasted 952Peanut ungerminated 821Peanut ungerminated 821Peanut germinated 610Peanut germinated 610Corn 367Corn 367Lentils 779Lentils 779

Hazel nuts 648 – 1000Hazel nuts 648 – 1000Wild rice flour 634 – Wild rice flour 634 –

752.5752.5Yam meal 637Yam meal 637Refried beans 622Refried beans 622Corn tortillas 448Corn tortillas 448Coconut 357Coconut 357Entire coconut meat 270Entire coconut meat 270Whole wheat 2200 Whole wheat 2200 White flour 258White flour 258White flour tortillas 123White flour tortillas 123Strawberries12Strawberries12

*In milligrams per 100 grams of dry weight

Phytic Acid content can be Phytic Acid content can be reduced by:reduced by:

SoakingSoaking CookingCooking Lactic Acid Fermentation – Lactic Acid Fermentation –

Requires a pH of less than Requires a pH of less than 5.55.5

Lectins: Sticky Protiens Lectins: Sticky Protiens the Other Antinutrient and the Other Antinutrient and

Immune DisruptorImmune Disruptor Present in wheat, corn, rye, barley, oats, rice, legume Present in wheat, corn, rye, barley, oats, rice, legume

& seed oils& seed oils Pass undigested into the blood stream – via endocytosisPass undigested into the blood stream – via endocytosis May be utilized by pathogenic microbes to be May be utilized by pathogenic microbes to be

transported to distant sites & may be utilized to form transported to distant sites & may be utilized to form biofilmsbiofilms

Lectins and Immune Lectins and Immune DisruptionDisruption

Wheat Germ Agglutinin up regulates Wheat Germ Agglutinin up regulates inflammatory cytokines (biochemical inflammatory cytokines (biochemical messengers)messengers)

Involved in acute and chronic Involved in acute and chronic inflammatory disordersinflammatory disorders

Contribute to neurodegenerative Contribute to neurodegenerative disease, inflammatory bowel disease disease, inflammatory bowel disease and a multitude of diseasesand a multitude of diseases

Decrease natural killer cell activity Decrease natural killer cell activity

Rheumatoid Arthritis (RA) is A Rheumatoid Arthritis (RA) is A Classic Example of Lectin-Induced Classic Example of Lectin-Induced

AutoimmunityAutoimmunity RA Antibody contains N Acetyl RA Antibody contains N Acetyl

Glucosamine which is specific for Glucosamine which is specific for WGAWGA

Lectins enter blood stream & bind to Lectins enter blood stream & bind to connective tissue making them stiff connective tissue making them stiff and inflamedand inflamed

Night shade vegetables are very Night shade vegetables are very high in lectins and are know to high in lectins and are know to trigger arthritistrigger arthritis

Lectins May Contribute to Lectins May Contribute to Food AllergiesFood Allergies

Peanut lectins are found in the blood Peanut lectins are found in the blood

stream four hours after consumptionstream four hours after consumption

Many food allergies are an immune Many food allergies are an immune attack on undigested lectinsattack on undigested lectins

Cause inflammation in the GI tract Cause inflammation in the GI tract and contribute to leaky gut and contribute to leaky gut syndromesyndrome

Lectins and Weight GainLectins and Weight Gain

Bind to insulin receptor on adipose Bind to insulin receptor on adipose (fat) cells causing unregulated (fat) cells causing unregulated glucose uptakeglucose uptake

Block effects of CCK which create Block effects of CCK which create satiety and block immune responsesatiety and block immune response

Inhibit digestive enzyme release and Inhibit digestive enzyme release and protein digestionprotein digestion

““What is food to What is food to one may be fierce one may be fierce poison to others.”poison to others.”

Lucretius (c. 99BC – c. 55BC)Lucretius (c. 99BC – c. 55BC) Roman Epicurean poet, Roman Epicurean poet,

philosopher philosopher and scientistand scientist

Celiac Disease (CD) vs. Celiac Disease (CD) vs. Wheat Allergy (WA) vs. Wheat Allergy (WA) vs.

Gluten IntoleranceGluten Intolerance

CD has a prevalence of approximately CD has a prevalence of approximately 1% of the US population1% of the US population

WA has a prevalence of approximately WA has a prevalence of approximately 5% of the US population5% of the US population

Gluten intolerance is estimated to Gluten intolerance is estimated to exist in 30 – 50% of individualsexist in 30 – 50% of individuals

Celiac DiseaseCeliac Disease Autoimmune disease as a result of self Autoimmune disease as a result of self

directed antibodies against the small directed antibodies against the small intestineintestine

Develops over months to yearsDevelops over months to years Causes malabsorption, malnutrition, Causes malabsorption, malnutrition,

skin disease and neurological diseaseskin disease and neurological disease Diagnosed by blood test demonstrating Diagnosed by blood test demonstrating

IgA antibodies against gliadin tissue IgA antibodies against gliadin tissue transglutaminase or by small bowel transglutaminase or by small bowel biopsybiopsy

Genetic markersGenetic markers

Wheat Allergy is an IgE Wheat Allergy is an IgE Mediated AllergyMediated Allergy

Gastrointestinal Gastrointestinal symptomssymptoms

Atopic dermatitisAtopic dermatitis HivesHives AsthmaAsthma AnaphylaxisAnaphylaxis

Gluten IntoleranceGluten Intolerance

Abdominal PainAbdominal Pain FatigueFatigue Skin rashSkin rash HeadacheHeadache Brain fogBrain fog Weight gainWeight gain

Joint PainJoint Pain DiarrheaDiarrhea NumbnessNumbness DepressionDepression AnemiaAnemia

Ill defined immune response to indigestion of gluten and is generally responsive to removal of gluten

Symptoms are often vague and can include:

Microbiota Thrive on Microbiota Thrive on Undigested GrainsUndigested Grains

Undigested polysaccharidys in grain Undigested polysaccharidys in grain serve as fuel source to the serve as fuel source to the

microbiota of the gut.microbiota of the gut.

Elimination of grains may cause an Elimination of grains may cause an imbalance of healthy flora which are imbalance of healthy flora which are critical for healthy immune functioncritical for healthy immune function

Fermented vegetables serve as Fermented vegetables serve as your source for beneficial your source for beneficial

microbiota which also contain the microbiota which also contain the FOS for bacterial growthFOS for bacterial growth

SummarySummary

High prevalence of CD, WA and gluten High prevalence of CD, WA and gluten intolerance in the general populationintolerance in the general population

““Gluten Free” does not necessarily mean Gluten Free” does not necessarily mean healthyhealthy

Phytic acid disrupts digestion and acts as an Phytic acid disrupts digestion and acts as an anti-nutrientanti-nutrient

Lectins are pro-inflammatory cell and Lectins are pro-inflammatory cell and hormone disruptors that should be avoidedhormone disruptors that should be avoided

Include lacto-fermented veggies at every Include lacto-fermented veggies at every mealmeal