1
656 has been confused by the variety of methods used in collecting the data. The problems presented in one of the recent major studies are reviewed. The significance of different types of clinical studies which have been published are evaluated and additional points of special importance are stressed. The aim is to suggest principles which will improve the quality of studies of this nature in the future not only for evaluating the use of anticoagulants but also for other forms of therapy. This work was aided by grants from the Lasker, Fullerton, and Guttman Foundations. DANGER AT WORK INDUSTRIAL accidents cause much misery, and waste men and money besides. Some people, perhaps, believe that every possible preventive measure has already been taken and that those accidents which still occur are the inevitable results of human fallibility. To them, the chief inspector of factories’ report 1 for 1961 will come as a shock. For the third successive year the number of accidents has risen, and the total of 192,517 represents an increase of 1% over 1960’s. True, this rate of increase is lower than that of 9% between 1959 and 1960; moreover, the number of accidents per 1000 persons employed has fallen marginally from 20-7 to 20-4, and the number of fatal accidents has also fallen, from 675 to 669. The conclusion of the chief inspector is that all the extra 1 % is accounted for by the increased number of accidents in the constructional industries; civil engineering was responsible for a third of the increase and building construction for the other two-thirds. There were 10% more accidents in these trades than in 1960. Accidents on building sites have become steadily more frequent over the past ten years; although the expansion of the industry and its labour force, the introduction of new and unfamiliar methods, and the statutory obligation to report accidents more fully may all contribute to these figures, the report concludes that safety standards on the sites have indeed deteriorated. In 1961, for example, 7% more young people were employed on building sites than in the previous year; but 27% more were injured. Already the construction regulations have been extended from building to civil engineering, and more " safety supervisors " are to be appointed; in addition, a British Standard specification for safety nets is to be intro- duced shortly. What effect these measures will have on next year’s figures remains to be seen. In 1961 25% of all accidents occurred during the handling of goods. The report exhorts industry to plan the safe move- ment of materials and welcomes the introduction of mechanical handling. 18% of accidents were due to falls, and 8% to persons being struck by falling objects; 7% involved transport, and 7% the use of hand tools. This pattern, says the report, is repeated year after year; but the accidents are not inevitable. Many could be prevented or at least mitigated by the wearing of protective clothing, especially boots and helmets. In factories the provision of goggles is still inadequate, and 25% of eye injuries were due to particles thrown off from improperly shielded machines. New industrial processes introduce new hazards. Increas- ingly, for example, firms are using radioactive tracers and ionising radiations. The manufacture of plastics, often carried on in old and unsuitable premises, may lead to the production of explosive mixtures of dust and air. A second report,2 on 1. Annual Report of the Chief Inspector of Factories, 1961. Cmnd 1816. H.M. Stationery Office. Pp. 102. 6s. 6d. 2. Annual Report of the Chief Inspector of Factories on Industrial Health, 1961. Cmnd 1815. H.M. Stationery Office. Pp. 63. 4s. industrial health, draws attention to the dangerous potentialities of some of the new metals now finding wide application. For example, the inhalation of cadmium or vanadium oxide as fine dust is followed by pneumonitis; and manganese-dioxide poisoning disturbs the extrapyramidal system. There were more cases of lead poisoning in 1961 than in any other year since the war; this was attributable to the numbers of lead-painted ships being broken up in the idle yards, although the greatest number of cases still stemmed from small factories manufacturing electrical accumulators. The report concedes that there is growing appreciation throughout industry of the need for positive action to render work safe and healthy. But organised industry could still do much more to publicise safety precautions and to inculcate safe habits of working in young employees. Too often young people are left to pick up their ways of work from older men who may themselves be careless of safety measures. Some safety-training centres have already been set up, but the effort has yet to become .nation-wide. The Ministry of Labour has approached several industries individually and has obtained their cooperation in developing safe working conditions. Further, the factory inspectorate has been augmented by 30 to a total of 480. But the heart of the problem lies in the attitude of the men at risk: safety will only be taken seriously on the shop floor if management first shows concern that it should be. Conference SYPHILIS FROM A CORRESPONDENT THE World Forum on Syphilis and other Trepone- matoses was held in Washington, D.C., on Sept. 4-8. Considerable anxiety was expressed concerning the recent rise in incidence of venereal syphilis in the U.S.A. (more than threefold in the past three years) which was believed to be due more than anything to a slackening of effort in earlier years following budgetary reductions. Reduced facilities had resulted in even more cases than formerly being treated by private practitioners, from whom fewer contacts were generally obtained for interview than in the case of patients treated in the clinics. Nevertheless American workers were confident that syphilis could be eradicated from the country by intensifying the existing methods of contact tracing and by " cluster testing " (testing associates of patients with syphilis not necessarily sexually involved), and by improving the liaison between the health departments and private practitioners. Extended legislation in the various States, to require the reporting of positive serum findings by serological laboratories, was also urged. The attitude of health departments for the great pox, it was felt, should resemble those already adopted towards smallpox. Little new was presented concerning treatment which, with penicillin, continues to give satisfactory results in all stages of all of the treponematoses. Treatment reactions, although sometimes serious, are not common enough to prejudice a control programme based on this drug. Simplified methods of diagnosis of syphilis are required, and the rapid plasma reaction (R.P.R.) demonstrated at the meeting will produce a result on specially prepared cards in a few minutes. The fluorescent treponemal antibody (F.T.A.) test holds promise as a much simpler reference test than the cumbersome if specific. treponemal immobilisation (T.P.I.) test. Some overseas participants did not wholly agree with the declared aim of " eradication ", considering that control" " was still a better word: eradication in one country without eradication in all did not seem to be feasible.

DANGER AT WORK

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656

has been confused by the variety of methods used in

collecting the data.The problems presented in one of the recent major

studies are reviewed.

The significance of different types of clinical studieswhich have been published are evaluated and additionalpoints of special importance are stressed. The aim is tosuggest principles which will improve the quality ofstudies of this nature in the future not only for evaluatingthe use of anticoagulants but also for other forms of

therapy.This work was aided by grants from the Lasker, Fullerton, and

Guttman Foundations.

DANGER AT WORK

INDUSTRIAL accidents cause much misery, and wastemen and money besides. Some people, perhaps, believethat every possible preventive measure has already beentaken and that those accidents which still occur are theinevitable results of human fallibility. To them, the chiefinspector of factories’ report 1 for 1961 will come as a shock.For the third successive year the number of accidents has

risen, and the total of 192,517 represents an increase of1% over 1960’s. True, this rate of increase is lower thanthat of 9% between 1959 and 1960; moreover, the numberof accidents per 1000 persons employed has fallen

marginally from 20-7 to 20-4, and the number of fatalaccidents has also fallen, from 675 to 669.

The conclusion of the chief inspector is that all the extra 1 %is accounted for by the increased number of accidents in theconstructional industries; civil engineering was responsible fora third of the increase and building construction for the othertwo-thirds. There were 10% more accidents in these tradesthan in 1960. Accidents on building sites have become steadilymore frequent over the past ten years; although the expansionof the industry and its labour force, the introduction of newand unfamiliar methods, and the statutory obligation to reportaccidents more fully may all contribute to these figures, thereport concludes that safety standards on the sites have indeeddeteriorated. In 1961, for example, 7% more young peoplewere employed on building sites than in the previous year; but27% more were injured. Already the construction regulationshave been extended from building to civil engineering, andmore " safety supervisors " are to be appointed; in addition,a British Standard specification for safety nets is to be intro-duced shortly. What effect these measures will have on nextyear’s figures remains to be seen.

In 1961 25% of all accidents occurred during the handlingof goods. The report exhorts industry to plan the safe move-ment of materials and welcomes the introduction of mechanical

handling. 18% of accidents were due to falls, and 8% to personsbeing struck by falling objects; 7% involved transport, and 7%the use of hand tools. This pattern, says the report, is repeatedyear after year; but the accidents are not inevitable. Manycould be prevented or at least mitigated by the wearing ofprotective clothing, especially boots and helmets. In factoriesthe provision of goggles is still inadequate, and 25% of eyeinjuries were due to particles thrown off from improperlyshielded machines.

New industrial processes introduce new hazards. Increas-

ingly, for example, firms are using radioactive tracers and

ionising radiations. The manufacture of plastics, often carriedon in old and unsuitable premises, may lead to the productionof explosive mixtures of dust and air. A second report,2 on1. Annual Report of the Chief Inspector of Factories, 1961. Cmnd 1816.

H.M. Stationery Office. Pp. 102. 6s. 6d.2. Annual Report of the Chief Inspector of Factories on Industrial Health,

1961. Cmnd 1815. H.M. Stationery Office. Pp. 63. 4s.

industrial health, draws attention to the dangerous potentialitiesof some of the new metals now finding wide application. For

example, the inhalation of cadmium or vanadium oxide as finedust is followed by pneumonitis; and manganese-dioxidepoisoning disturbs the extrapyramidal system. There were morecases of lead poisoning in 1961 than in any other year since thewar; this was attributable to the numbers of lead-painted shipsbeing broken up in the idle yards, although the greatest numberof cases still stemmed from small factories manufacturingelectrical accumulators.

The report concedes that there is growing appreciationthroughout industry of the need for positive action torender work safe and healthy. But organised industrycould still do much more to publicise safety precautionsand to inculcate safe habits of working in young employees.Too often young people are left to pick up their ways ofwork from older men who may themselves be careless of

safety measures. Some safety-training centres have

already been set up, but the effort has yet to become.nation-wide. The Ministry of Labour has approachedseveral industries individually and has obtained their

cooperation in developing safe working conditions.Further, the factory inspectorate has been augmented by30 to a total of 480. But the heart of the problem lies inthe attitude of the men at risk: safety will only be takenseriously on the shop floor if management first showsconcern that it should be.

Conference

SYPHILIS

FROM A CORRESPONDENT

THE World Forum on Syphilis and other Trepone-matoses was held in Washington, D.C., on Sept. 4-8.

Considerable anxiety was expressed concerning the recentrise in incidence of venereal syphilis in the U.S.A. (more thanthreefold in the past three years) which was believed to be duemore than anything to a slackening of effort in earlier yearsfollowing budgetary reductions. Reduced facilities had resultedin even more cases than formerly being treated by privatepractitioners, from whom fewer contacts were generallyobtained for interview than in the case of patients treated in theclinics. Nevertheless American workers were confident that

syphilis could be eradicated from the country by intensifyingthe existing methods of contact tracing and by " cluster

testing " (testing associates of patients with syphilis not

necessarily sexually involved), and by improving the liaisonbetween the health departments and private practitioners.Extended legislation in the various States, to require the

reporting of positive serum findings by serological laboratories,was also urged. The attitude of health departments for thegreat pox, it was felt, should resemble those already adoptedtowards smallpox.

Little new was presented concerning treatment which, withpenicillin, continues to give satisfactory results in all stages ofall of the treponematoses. Treatment reactions, althoughsometimes serious, are not common enough to prejudice a

control programme based on this drug. Simplified methods ofdiagnosis of syphilis are required, and the rapid plasma reaction(R.P.R.) demonstrated at the meeting will produce a result onspecially prepared cards in a few minutes. The fluorescenttreponemal antibody (F.T.A.) test holds promise as a muchsimpler reference test than the cumbersome if specific.treponemal immobilisation (T.P.I.) test.Some overseas participants did not wholly agree with the

declared aim of " eradication ", considering that control" "was still a better word: eradication in one country withouteradication in all did not seem to be feasible.