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D.1.1 Describe the 4 processes needed for the spontaneous origin of life on Earth
3. Formation of polymers that can self
replicate- this allows inheritance of
characteristics.
4. Development of membranes, to form
spherical droplets, with an internal
chemistry different from the surroundings,
including polymers that held genetic
information.
1. Chemical reactions to produce simple organic molecules from inorganic molecules:
Amino acids, Water, CO2, Ammonia.
2. Assembling of these organic molecules into polymers: Polypeptides from amino acids.
D.1.2 Outline the experiments of Miller and Urey into the origin of organic compounds
Reproduction of environment that existed before on Earth :
1. Methane, Hydrogen, Ammonia inserted
2. Water cycle simulation; heat –evaporate-cooled-condensed
3. UV radiation (no ozone layer before)
4. Electrical sparks = lightning
D.1.3 State that comets may have delivered organic compounds
Panspermia- the theory concerned with the arrival of material from outer space.
Hundreds of meteorites and comets hitting the early Earth brought with them organic
molecules formed by abiotic reactions in outer space.
Extraterrestrial organic compounds, including amino acids, have been found in modern
meteorites, and it seems likely that these bodies could have seeded the early Earth with
organic compounds.
D.1.4 Discuss possible locations where conditions would have allowed the synthesis of organic compounds
Tidal pools (clay-catalyst
polymerisation, minerals)
Deep sea thermal vents (heat, minerals in water)
Volcanoes (water vapours, minerals, heat)
In space (amino acids in dust)
D.1.5 Outline two properties of RNA that would have allowed it to play a role in the origin of life
D.1.5 Outline two properties of RNA that would have allowed it to play a role in the origin of life
1. RNA can self-replicate
Short polymers of ribonucleotides can be synthesized abiotically in the laboratory.
If these polymers are added to a solution of ribonucleotide monomers, sequences
up to 10 based long are copied from the template according to the base-pairing
rules.
If zinc is added, the copied sequences may reach 40 nucleotides with less than
1% error.
2. RNA can act as an enzyme – Ribozymes.
D.1.5 Outline two properties of RNA that would have allowed it to play a role in the origin of life
RNA can enzymatically catalyze metabolic reactions:
• RNA can catalyze the formation of more RNA
• RNA can bind amino acids and form peptide linkages
RNA-directed protein synthesis may have begun as weak binding of specific amino acids to
bases along RNA molecules, which functioned as simple templates holding a few amino
acids together long enough for them to be linked.
D.1.6 State that living cells may have been preceded by protobionts, with an internal chemical environment different
from their surroundings
A Protobiont is an aggregate of abiotically produced organic molecules surrounded by a
membrane or a membrane-like structure. Protobionts exhibit some of the properties
associated with life, including simple reproduction, metabolism and excitability, as well as
the maintenance of an internal chemical environment different from that of their
surroundings.
D.1.7 Outline the contribution of prokaryotes to the creation of an oxygen-rich atmosphere
Anaerobic bacteria are believed to be the first forms of life on
Earth. They consumed organic materials and reproduced to
such numbers that competition was high and food was
scarce. It is unclear how it happened but some bacteria
evolved to become photosynthetic.
Photosynthetic prokaryotes began photosynthesis:
• Free oxygen is accumulated in the Earth’s
atmosphere.
• The formation of an ozone layer in the upper
atmosphere started.
• Incidence of UV light reaching the Earth’s surface
reduced thanks top ozone layer.
• Terrestrial existence (rather than life restricted to
below the water surface) became a possibility.
Stromatolites: Earth’s oldest fossil made of rock formed by growth of blue-green bacteria
Modern Cyanobacteria
D.1.8 Discuss the endosymbiontic theory for the origin of eukaryotes
Evidence for endosymbiotic theory:
Mitochondria and Chloroplasts have their own DNA; a naked loop
similar to that of prokaryotes.
They have their own double membrane.
They are able to replicate themselves
They have the ability to perform protein synthesis using ribosomes.