Cystic Fibrosis (SIS- tik fi-BRO-sis)

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Cystic Fibrosis (SIS- tik fi-BRO-sis). By: Eleftheria Ria Karoutis. What is Cystic Fibrosis?. Cystic fibrosis is also known as CF Inherit two faulty genes for the disease Mainly affects lungs , pancreas, liver, intestines, sinuses, and sex organs. Causes of the disorder. - PowerPoint PPT Presentation

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Cystic Fibrosis (SIS-tik fi-BRO-sis)

Cystic Fibrosis (SIS-tik fi-BRO-sis) By: Eleftheria Ria KaroutisWhat is Cystic Fibrosis?Cystic fibrosis is also known as CFInherit two faulty genes for the diseaseMainly affects lungs, pancreas, liver, intestines, sinuses, and sex organs.

Causes of the disorder..CF cannot be "caught" like a cold or the fluCaused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR)Can only get it if his/her parents both are carriers. Boys and girls are equally likely to have CF.Researchers noticed higher levels of some essential fatty acids in people with CF.

What are the symptoms?CF causes the body to produce large amounts of thick mucusAffects the lungs, digestive and reproductive systemsMucus in the airways causes wheezing, coughing, and trouble breathingLarge amounts of mucus blocking the pancreas prevents enzymes from being released98% of men are infertile, women can bear children but can pass down CFCan develop diabetes, or suffer from liver and lung damage

How is it inherited? A double recessive allele is needed for cystic fibrosis to be apparentFound on chromosome 7Chloride channel protein that is critical for normal functioning of multiple organs

Is there a treatment?Back in the 50s patients had a life expectancy of only 5 yearsBefore antibiotics were available approximately 75% of children with CF died before the age of tenTreatments will vary from person to person Vibrations to help loosen the mucus Mucus thinners, antibiotics, anti-inflammatories, and bronchodilators Enzyme supplements

Who does it affect?Like any other defect, Cystic Fibrosis affects the patients, the patients family and society as a whole.

Impact on society..

Recent advances/direction of current researchThe gene responsible for cystic fibrosis was only discovered in 1989Scientists have made steady progress in understanding CF and developing strategies to defeat itFoundations provide the resources and support for studies that are leading to important new therapies and better treatmentDiscoveries are being turned into potential drugs that attack both the symptoms of CF and the cause (faulty gene)

Are there any research foundations/ support groups/ charities?

BibliographyChildren with Exceptionalities in Canadian Classrooms- Margret Winzer (book)