Cystic Fibrosis

Will Fagahan

Ryan Iglodi

2A

Fuck MArc FUCKING JOE

Cystic Fibrosis

Cystic fibrosis is a disease passed down through families that causes thick, sticky mucus to build up in the lungs, digestive tract, and other areas of the body.


General Description and Affected Areas

This mucus builds up in the breathing passages of the lungs and in the pancreas, the organ that helps to break down and absorb food.


Parts of Respiratory System Affected

Cystic fibrosis (CF) is caused by a defective gene which causes the body to produce abnormally thick and sticky fluid, called mucus.


Cause

•Antibiotics •Inhaled medicines to help open the airways•DNAse enzyme therapy to thin mucus and make it easier to cough up•High concentration of salt solutions (hypertonic saline)•Flu vaccine and pneumococcal polysaccharide vaccine


Treatment

Antibiotics (such as ciprofloxacin [Cipro] and tobramycin [TOBI])Bronchodilators (such as albuterol or salmeterol)Anticholinergics (such as Atrovent)DNase (such as Pulmozyme)Mucolytics (such as acetylcysteine)Nonsteroidal anti-inflammatory drugs (NSAIDs) (such as Motrin)Membrane stabilizers (such as cromolyn) Corticosteroids (such as prednisone, Medrol, or Flovent Diskus)


Pharmacology

Inflammation, obstruction and infection cause:

Lung Damage then Lung Scarring thenPoor Lung Function

It progressively gets worse.


Progression of the Disease

- Children with CF are generally healthy until adulthood-Lung disease eventually worsens until the person becomes disabled- Average life expectancy is 37 years


Expected Outcomes for Recovery

Documents

Cystic Fibrosis