CVN - ELENA CERRADA LAMUELA...Dra. Mª Jesús Rodríguez-Yoldi (Departamento de Farmacología y Fisiología, UZ) Dr. Peter Skabara (Strathclyde University, UK) Dr. Paul Dyson (École

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ELENA CERRADA LAMUELAGenerated from: Editor CVN de FECYTDate of document: 10/10/2019v 1.4.0d067b51296e4d6b45c22e0e8ba25b623

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Summary of CV

This section describes briefly a summary of your career in science, academic and research; themain scientific and technological achievements and goals in your line of research in the medium-and long- term. It also includes other important aspects or peculiarities.

Doctor in Chemical Sciences in 1994. Full Professor at the University of Zaragoza since 2008.Habilitación in January 2006.I have supervised 5 Doctoral Thesis at the University of Zaragoza. I'm supervising 2 PhDstudents at this moment.I have supervised the following projects at the University of Zaragoza: 5 TFM (Master's thesis),8 TFG (Final year projects), 5 TAD (Academically Directed Jobs), 2 DEA (Advanced StudiesDiplomas), 5 Postgraduate works, 12 Bachelor Thesis (degree of Chemistry) and 3 Finalyear projects (degree of Chemical Engineering)I have participated in 32 research projects of national and regional competitive nature. I havealso participated in projects financed by companies such as Torrecid S.A., Gres de Aragón,Muel Ceramics Workshop School, among others.I have presented posters or communications in 64 international and national congresses. Ihave enjoyed two stays at Durham University in 1992 and Southampton in 1999. For which Iwas awarded a scholarship funded by CAI and the Royal Society, respectively.My research has always been based on the synthesis of noble metal complexes with aspecific purpose, based on their applicability. With that idea I have focused my research onproperties such as electrical conductivity, catalysis, vapochromic compound sensors, solubilityin aqueous media and biomedical applications mainly in the treatment against cancer andAlzheimer's.Many collaborations both national and international have been stablished during this research,most of them active:Dra. Mª Jesús Rodríguez-Yoldi (Departamento de Farmacología y Fisiología, UZ)Dr. Peter Skabara (Strathclyde University, UK)Dr. Paul Dyson (École Polytechnique Fedérale de Lausanne, Suiza)Dra. Angela Casini (Cardiff University, UK)Dra. Christelle Hureau (Universidad de Toulouse, Francia)Dr. Ignacio Matias (Universidad Pública de Navarra)Dr. Manuel Arruebo Gordo (Instituto de Nanociencia de Aragón)Dr. Ignacio Ochoa Garrido (Instituto de Investigación en Ingeniería de Aragón)Academic positions: I have been Armonizador in Chemistry for EvAU exams at Universityof Zaragoza (from 2014 to September 2018), Member of the Teaching Committee and theTeaching Evaluation Commission of the Polytechnic School of Huesca (from 2008 until 2019),President of the Organizing Committee of the Chemistry Olympiad in Aragon (from 2014to 2018), Member of the Academic Commission of Doctorate of Inorganic Chemistry at theUniversity of Zaragoza (2012-2015), Member of the Commission Quality Assurance Degreein Environmental Sciences at the Polytechnic School (2010-2012), Member of the Committeefor the Preparation of the Degree Report in Agriculture Engineering and Rural Environment(2009–2010) and Member of the University Senate (2002- 2004).I have participated in 6 Projects in Teaching Innovation:

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PIECyT-09-1-152 (2008-09), PIECyT-10-1-303 (2009-10), PIECyT-11-1-170 (210-11),PIECyT-12-1-248, PIIDUZ-17-249 and PIIDUZ-18-331(2017-2019).I’m referee for the following journals: Bioorganic Chemistry, ChemBioChem, ChemicalCommunications, ChemMedChem, Dalton Transactions, Inorganic Chemistry, InorganicChemistry Communications, Inorganics, International Journal of Molecular Sciences, Journalof Inorganic Biochemistry, Journal of the Chemical Education, Journal of Materials Chemistry,Journal of the Organic Chemistry, Organometallics and RSC Advances.

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General quality indicators of scientific research

This section describes briefly the main quality indicators of scientific production (periods ofresearch activity, experience in supervising doctoral theses, total citations, articles in journals ofthe first quartile, H index...). It also includes other important aspects or peculiarities.

Periods of research activity: 4Supervision of Doctoral Thesis in the last 10 years: 4Total cites: 1514.Publications: 73, and 5 book chapter.Publications (Q1): 53. h-Index: 22.

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ELENA CERRADA LAMUELA

Surname(s): CERRADA LAMUELAName: ELENADNI: 25437640PORCID: 0000-0003-2457-3674ResearcherID: K-6790-2014Date of birth: 15/07/1967Gender: FemaleLand line phone: 876553529Email: [email protected] phone: 646665410

Current professional situation

Employing entity: Universidad de ZaragozaDepartment: Química Inorgánica, Facultad de CienciasProfessional category: PROFESOR TITULARStart date: 09/06/2008Type of contract: Civil servant Dedication regime: Full timeSecondary (UNESCO code): 230318 - MetalsIdentify key words: Organometallic chemistry; Antitumors; Ligand design; Biomedicine

Previous positions and activities

Employing entity Professional category Start date1 Universidad de Zaragoza PROFESOR AYUDANTE DOCTOR 20072 Universidad de Zaragoza PROFESOR ASOCIADO 19943 Universidad de Zaragoza Becario Predoctoral 1991

1 Employing entity: Universidad de Zaragoza Type of entity: UniversityProfessional category: PROFESOR AYUDANTE DOCTORStart-End date: 2007 - 2008 Duration: 1 year

2 Employing entity: Universidad de Zaragoza Type of entity: UniversityProfessional category: PROFESOR ASOCIADOStart-End date: 1994 - 2007

3 Employing entity: Universidad de Zaragoza Type of entity: UniversityProfessional category: Becario PredoctoralStart-End date: 1991 - 1994 Duration: 4 years

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Education

University education

1st and 2nd cycle studies and pre-Bologna degrees

University degree: Higher degreeName of qualification: Licenciado en Ciencias QuimicasDegree awarding entity: Universidad de Zaragoza Type of entity: UniversityDate of qualification: 06/1990

Doctorates

Doctorate programme: Ciencias QuimicasDegree awarding entity: Universidad de Zaragoza Type of entity: UniversityDate of degree: 09/06/1994

Language skills

Language Listening skills Reading skills Spoken interaction Speaking skills Writing skillsFrench A1 A1 A1 A1English C1 C1 C1 C1

Teaching experience

Experience supervising doctoral thesis and/or final year projects

1 Project title: Trabajo Fin de Grado en Biotecnología: Estudio de la actividad antitumoral de complejos metálicospor hipertermiaEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Ignacio Balbás VaqueroDate of reading: 21/02/2019

2 Project title: Trabajo Fin de Grado en Quimica: Diseño de potenciales agentes cancerígenos.Entity: Universidad de Zaragoza. Facultad de CienciasStudent: María Lahoz SanchezDate of reading: 27/09/2018

3 Project title: Trabajo Fin de Grado de Químicas: ‘Desarrollo de potenciales agentes cancerigenos.Entity: Universidad de Zaragoza. Facultad de CienciasStudent: Paula Azcárate SedanoDate of reading: 28/09/2017

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4 Project title: Trabajo Fin de Máster Universitario en Quimica Molecular y Catálisis Homogénea : Diseño decomplejos de oro para el tratamiento antitumoral por hipertemiaEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Adrian Alconchel SanchezDate of reading: 28/09/2017

5 Project title: Trabajo fin de Máster Universitario en Biología Molecular y Celular: Evaluación in vitro de la actividadantitumoral de complejos de oro con ligandos ditiocarbamatoCo-director of thesis: Mª Jesús Rodriguez-YoldiEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Javier Quero BellidoDate of reading: 28/09/2017

6 Project title: Trabajo Fin de Grado de Biotecnología: Estudio de las propiedades anticancerígenas de complejosmetálicos de oroEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Raquel Alvarez UrdiolaDate of reading: 11/07/2017

7 Project title: Trabajo Fin de Grado de Biotecnología: Estudio de las propiedades anticancerígenas de complejosmetálicos de oro con ligandos ditiocarbamatoEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Javier Quero BellidoDate of reading: 09/07/2016

8 Project title: Trabajo Fin de Grado de Químicas: Complejos metálicos como potenciales agentes terapéuticosanticancerígenos”Entity: Universidad de Zaragoza. Facultad de CienciasStudent: Pilar Castellnou ArenasDate of reading: 08/07/2016

9 Project title: Trabajo fin de Máster Universitario en Biología Molecular y Celular: Estudios de alquino derivados deoro como potenciales anticancerígenosCo-director of thesis: Mª Jesús Rodriguez-YoldiEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Ines Mármol PegueroDate of reading: 07/07/2016

10 Project title: Trabajo fin de Máster Universitario en Iniciación a la Investigación en Ciencias Veterinarias: Ensayode compuestos de oro en células cancerígenasCo-director of thesis: Mª Jesús Rodriguez-YoldiEntity: Universidad de Zaragoza. Facultad de VeterinariaStudent: Lidia Puértolas SotoDate of reading: 18/12/2015

11 Project title: Tesis Doctoral: 'Síntesis dirigida de compuestos metálicos solubles en agua en función de susaplicaciones biomédicas'Entity: Universidad de ZaragozaStudent: Elena Atrian BlascoDate of reading: 04/12/2015

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12 Project title: Trabajo Fin de Grado de Biotecnología: “Aplicación de un complejo metálico de oro(III) con finesterapéuticos anticancerígenosEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Teresa Fuertes NovellaDate of reading: 10/07/2015

13 Project title: Trabajo Fin de Grado de Biotecnología: “Ensayo de un derivado metálico de oro(I) en células decarcinoma de colon humanoEntity: Universidad de Zaragoza. Facultad de CienciasStudent: Ines Marmol PequeroDate of reading: 09/07/2015

14 Project title: Trabajo Fin de Grado de Biotecnología: “Ensayo de derivados metálicos como agentes terapéuticosanticancerígenos”Entity: Universidad de Zaragoza. Facultad de CienciasStudent: Rocio Pérez RáulDate of reading: 09/07/2014

15 Project title: Trabajo Academicamente Dirigido (TAD): Síntesis de derivados metálicos solubles en agua comopotenciales anticancerígenos””Entity: Universidad Zaragoza. Facultad CienciasStudent: Rebeca MonteagudoDate of reading: 02/07/2014

16 Project title: Posgrado de iniciacion a la investigacion: “Síntesis de complejos de oro (III) con ligandosditiocarbamatos con potencial anticancerígeno”Entity: Universidad de Zaragoza. Facultad de CienciasStudent: Silvia Cabello LlorensDate of reading: 16/12/2013

17 Project title: Trabajo Academicamente Dirigido (TAD): Complejos metálicos solubles en agua con potencialesaplicaciones como anticancerígenos”.Entity: Universidad Zaragoza. Facultad CienciasStudent: Alejandro TomásDate of reading: 19/06/2013

18 Project title: Tesis Doctoral: Diseño de compuestos de oro como agentes terapéuticos anticancerígenosEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Mª Elena García MorenoDate of reading: 23/11/2012

19 Project title: Trabajo Academicamente Dirigido (TAD): Complejos metálicos solubles en agua con potencialesaplicaciones como catalizadores y/o anticancerígenos”Entity: Zaragoza. Facultad / Escuela: Facultad de cienciasStudent: Silvia Cabello LlorensDate of reading: 09/2012

20 Project title: MASTER: Síntesis dirigida de compuestos solubles en agua Master Universitario en InvestigaciónQuímicaEntity: Zaragoza Facultad/Escuela: Facultad de Ciencias

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Student: Elena Atrian BlascoDate of reading: 07/2012

21 Project title: Tesis Doctoral: Síntesis y aplicaciones de complejos de oro(I) solubles en agua y en medioshidroalcoholicosEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Elena Vergara TorralbaDate of reading: 22/10/2009

22 Project title: D.E.A.: Síntesis de fosfinas solubles en agua y estudio de su reactividad frente a complejos de oro(I)Entity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Elena Garcia MorenoDate of reading: 09/2009

23 Project title: Trabajo de Postgrado: Complejos de oro como precursores de superficies metálicas sobrecerámicasEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Mª José Bolsa TellaDate of reading: 12/2008

24 Project title: Trabajo de Postgrado: Estudio de complejos de oro con derivados de 1,3,5-triaza-7-fosfadamantano(PTA) solubles en aguaEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Elena Gracía MorenoDate of reading: 12/2008

25 Project title: Trabajo Academicamente Dirigido (TAD): Derivados de paladio solubles en agua. Estudio de suactividad catalíticaEntity: Zaragoza. Facultad / Escuela: Facultad de cienciasStudent: Rebeca Matute RamírezDate of reading: 09/2008

26 Project title: D.E.A.: Síntesis y aplicaciones de compuestos de oro solubles en agua y en medios hidroalcohólicosEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Elena Vergara TorralbaDate of reading: 09/2005

27 Project title: Trabajo Academicamente Dirigido (TAD): Derivados polinucleares con el ligando “pincer”Bis(2-feniltiol)fenilfosfina. Estudio de su comportamiento frente a compuestos orgánicos volátiles”Entity: Zaragoza Facultad / Escuela: Facultad de cienciasStudent: Patricia Coderque TomásDate of reading: 09/2005

28 Project title: Tesis Doctoral: Alquinotiolato y ditioleno complejos en la síntesis de nuevos materialesEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Nora Lardies MiazzaDate of reading: 25/01/2005

29 Project title: Tesis de Licenciatura: Coordinación intramolecular C,S del benceno ditiol. Preparación decompuestps dinucleares y estudio de su actividad cataliticaEntity: Zaragoza Facultad / Escuela: Ciencias

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Student: Marta Soria PozaDate of reading: 02/2004

30 Project title: Proyecto fin carrera: Compuestos de oro como catalizadores en reacciones de cicloadicion1,3-dipolar a nitronasEntity: Zaragoza Facultad / Escuela: Escuela Politécnica de HuescaStudent: Ana Adé DominguezDate of reading: 04/2003

31 Project title: Tesis Doctoral: Reactividad de ligandos coordinados: nitronas y ditiolatos polifuncionalesEntity: Zaragoza Facultad/Escuela: Facultad de CienciasStudent: Ana Moreno RuizDate of reading: 17/12/2001

32 Project title: Tesis de Licenciatura: Mono-, (2,6), (3,5)-(Trifluorometil)fenil derivados de Ni(II) y Au(I)Entity: Zaragoza Facultad / Escuela: CienciasStudent: Ana Carmen Fernández SoriaDate of reading: 02/2001

33 Project title: Proyecto fin carrera: Dadores funcionalizados derivados del tetratiafulvaleno: Síntesis y reactividadfrente a complejos metálicosEntity: Zaragoza Facultad / Escuela: Escuela Politécnica de HuescaStudent: Cristina Diaz LainDate of reading: 01/2001

34 Project title: Tesis de Licenciatura: Estudio de dos ligandos pincer: P,S,S’: bis(2-feniltiolato)fenil fosfina ybis(2-tioanisol)fenil fosfinaEntity: Zaragoza Facultad / Escuela: CienciasStudent: Asunción Luquín MartinezDate of reading: 06/2000

35 Project title: Proyecto fin carrera: Complejos de coordinación conductores. De compuestos moleculares apolímerosEntity: Zaragoza Facultad / Escuela: Escuela Politécnica de HuescaStudent: Asunción Sabater GraciaDate of reading: 12/1999

36 Project title: Tesis de Licenciatura: Reactividad de tiolatos polifuncionales. Ligandos P-S y C-S dadoresEntity: Zaragoza Facultad / Escuela: CienciasStudent: Marta Cera PuenteDate of reading: 09/1999

37 Project title: Tesis de Licenciatura: Bis(2-feniltiol)fenilfosfina como ligando di-(S,S') o tri-dentado(P,S,S') frente acentros metálicos de Sn(IV), Ni(II) y Pd(II)Entity: Zaragoza Facultad / Escuela: CienciasStudent: Cristina Pozo GonzaloDate of reading: 02/1999

38 Project title: Tesis de Licenciatura: El radical 2,4,6-triisopropilfenil (Trip) en la química del Niquel (II)Entity: Zaragoza Facultad / Escuela: CienciasStudent: José Félix Ba Royo

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Date of reading: 02/1999

39 Project title: Tesis de Licenciatura: 1,2,3-Tiadiazoles como precursores de alquinotiolato y ditioleno complejosEntity: Zaragoza Facultad / Escuela: CienciasStudent: Nora Lardiés MiazzaDate of reading: 09/1998

40 Project title: Tesis de Licenciatura: Fosfinotiolato complejos de estaño como precursores de derivadosheteronuclearesEntity: Zaragoza Facultad / Escuela: cienciasStudent: Jesús AznarDate of reading: 02/1998

41 Project title: Tesis de Licenciatura: Tioderivado complejos de Ag, Cu y Sn. Aplicaciones a las síntesis deditiolatos asimétricosEntity: Zaragoza Facultad / Escuela: CienciasStudent: José Javier LázaroDate of reading: 02/1998

42 Project title: Tesis de Licenciatura: Compuestos de oro(I) y oro(III) con el ligando hetrocíclico1,3-ditiol-2-selona-4,5-dimercapto (dmise)Entity: Zaragoza facultad / Escuela: cienciasStudent: Pedro Antonio SorollaDate of reading: 09/1997

43 Project title: Tesis de Licenciatura: Tiolato frente a ditiolato en la transformación de TTBEO en DDDT.Preparación y estudio de sus complejos metálicosEntity: ZaragozaFacultad / Escuela:cienciasStudent: José Felipe García GascaDate of reading: 06/1997

44 Project title: Tesis de Licenciatura: Síntesis de complejos metálicos con nitronas. Estudio comparativo con losligandos libres.Entity: Zaragoza Facultad / Escuela:CienciasStudent: Ana Moreno RuizDate of reading: 02/1997

Participation in innovative teaching projects

1 Project title: PIIDUZ_17_233: RED EULES, RED INTERDISCIPLINAR DE INVESTIGACIÓN E INNOVACIÓNEDUCATIVA EN ENTORNOS ULEARNING EN EDUCACIÓN SUPERIORType of participation: Team memberTime of working relationship: For a limited timeFunding entity: Universidad de Zaragoza Type of entity: UniversityStart-End date: 01/10/2018 - 01/10/2019 Duration: 1 year

2 Project title: PIIDUZ_17_249: RED EULES, RED INTERDISCIPLINAR DE INVESTIGACIÓN E INNOVACIÓNEDUCATIVA EN ENTORNOS ULEARNING EN EDUCACIÓN SUPERIORType of participation: Team memberTime of working relationship: For a limited timeFunding entity: Universidad de Zaragoza Type of entity: University

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Start-End date: 01/10/2017 - 01/10/2018 Duration: 1 year

3 Project title: PIECYT_12_1_248: Titulo: DÉCIMO ANIVERSARIO DE LA CATÁSTROFE DEL PRESTIGE: UNAOPORTUNIDAD PARA LA SENSIBILIZACIÓN Y EL ANÁLISIS MEDIOAMBIENTAL EN EL ÁMBITO ACADÉMICODEL GRADO DE CCAAType of participation: Team memberTime of working relationship: For a limited timeFunding entity: Universidad de Zaragoza Type of entity: UniversityStart-End date: 2012 - 2013 Duration: 1 year

4 Project title: PIECYT_11_1_170. Titulo: ANÁLISIS INTERDISCIPLINAR DE CASOS BASADOS EN EL USOMETODOLOGÍAS ACTIVAS PARA EL APRENDIZAJE POR COMPETENCIAS. Grado Ciencias AmbientalesType of participation: Team memberTime of working relationship: For a limited timeFunding entity: Universidad de Zaragoza Type of entity: UniversityStart-End date: 2011 - 2012 Duration: 1 year

5 Project title: PIECyT_10_1_303. El planteamiento de actividades interdisciplanares basadas en el usometodologías activas para el aprendizaje por competencias. Grado Ciencias AmbientalesType of participation: Team memberTime of working relationship: For a limited timeFunding entity: Universidad de Zaragoza Type of entity: UniversityStart-End date: 2010 - 2011 Duration: 1 year

6 Project title: PIECyT_09_1_152. Título: La resolución de casos en un ámbito interdisciplinar dentro de lasCiencias Ambientales: uso y aplicación de metodologías activas. Grado Ciencias AmbientalesType of participation: Team memberTime of working relationship: For a limited timeFunding entity: Universidad de Zaragoza Type of entity: UniversityStart-End date: 2009 - 2010 Duration: 1 year

Other activities/achievements not included above

1 Description of the activity: Miembro electo de Comisión de Garantia de Calidad del Grado de CienciasAmbientales desde 2010Organising entity: Escuela Politecnica de Huesca Type of entity: UniversityEnd date: 2012

2 Description of the activity: Miembro de Comisión de elaboración de la Memoria del Grado en IngenieríaAgroalimentaria y del Medio RuralOrganising entity: Escuela Politécnica de Huesca Type of entity: UniversityEnd date: 01/03/2010

3 Description of the activity: Miembro electo del Claustro universitario desde 2002Organising entity: Universidad de Zaragoza Type of entity: UniversityEnd date: 2004

4 Description of the activity: Armonizadora de Química en las Pruebas de acceso a la Universidad desde julio2014 hasta septiembre de 2018Organising entity: Universidad de Zaragoza Type of entity: University

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5 Description of the activity: Miembro Comisión Académica de Doctorado de Química Inorgánica desdeseptiembre de 2012Organising entity: Universidad de Zaragoza Type of entity: University

6 Description of the activity: Miembro electo de Comisión de Docencia desde año 2007Organising entity: Escuela Politecnica de Huesca Type of entity: University

7 Description of the activity: Presidenta del comité organizador de la Olimpiada en Quimica en Aragón desde2015 hasta 2018Organising entity: Colegio Oficial de Quimicos de Aragon y Navarra

Healthcare experience

Other activities/achievements not included above

1 Other relevant activities: COLABORACION con el departamento de TOXICOLOGIA del Hospital CLINICO deZaragoza para la determinación y cuantificación de sustancias volátiles en suero y sangreEntity where project took place: Universidad deZaragoza

Type of entity: University

End date: 1999

2 Other relevant activities: COLABORACION con el departamento de TOXICOLOGIA del Hospital CLINICO deZaragoza para la puesta a punto de un sistema de detección de sustancias tóxicas por cromatografía de gases.Entity where project took place: Universidad deZaragoza


End date: 1996

Scientific and technological experience

Scientific or technological activities

R&D projects funded through competitive calls of public or private entities

1 Name of the project: Grupo Consolidado DGA E07_17R Química de oro y plataEntity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): M Concepción GimenoNº of researchers: 8Funding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain

Start-End date: 01/01/2017 - 29/12/2019Total amount: 41.770 €

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2 Name of the project: Aplicaciones de Compuestos de Oro en Fotofísica, Medicina y Catálisis.CTQ2016-75816-C2-1-P.Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): M Concepción GimenoStart-End date: 30/12/2016 - 29/12/2019Total amount: 180.290 €

3 Name of the project: Alianza tecnológica para completar el ciclo de producción agroindustrial y forestal.ENTIDAD FINANCIADORA: SUDOE (Fondos FEDER), SOE1/P1/E0123Entity where project took place: Universidad de ZaragozaCity of entity: SpainName principal investigator (PI, Co-PI....): M Jesús Rodriguez-YoldiNº of researchers: 8Start-End date: 30/06/2016 - 30/06/2019Total amount: 125.000 €

4 Name of the project: Ayuda económica para la organización de Congresos de carácter científico(Convocatoria 2017)Entity where project took place: Universidad ZaragozaCity of entity: Zaragoza, SpainName principal investigator (PI, Co-PI....): Elena CerradaNº of researchers: 4Start-End date: 01/01/2017 - 31/12/2017Total amount: 1.397,59 €

5 Name of the project: Grupo Emergente de Organocatálisis asimétrica E104Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): Raquel Perez HerreraFunding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain


6 Name of the project: Impacto de las nuevas tecnologías de procesado en la calidad, seguridad y valornutritivo de los alimentos (CI-2014/001-1)Entity where project took place: Campus IberusName principal investigator (PI, Co-PI....): Rafael PaganStart-End date: 01/01/2015 - 31/12/2016Total amount: 12.200 €

7 Name of the project: Nuevas Estrategias para la Síntesis Orientada de Complejos del Grupo 11 conAplicación Óptica, Biológica y Catalítica. (CTQ2013-48635-C2-1-P)Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAStart-End date: 01/01/2014 - 31/12/2016Total amount: 192.390 €

8 Name of the project: Grupo Emergente de Organocatálisis asimétrica E104Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): Raquel Perez-HerreraFunding entity or bodies:

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Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain


9 Name of the project: Grupo Consolidado de Quimica organometalica aplicada (QOA) E101Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): Mariano LagunaNº of researchers: 8Funding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain


10 Name of the project: Grupo Emergente de Quimica organometalica aplicada (QOA) E101Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): Mariano Laguna CastrilloFunding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain


11 Name of the project: Investigación en Tecnologías de Líquidos iónicos para Aplicaciones Industriales(CENIT LIQUION)Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEACity of entity: Zaragoza,Name principal investigator (PI, Co-PI....): Mariano Laguna CastrilloFunding entity or bodies:Ministerio de Educación y Ciencia (CENIT)

Start-End date: 08/2010 - 12/2013Total amount: 120.000 €

12 Name of the project: Grupo Emergente de Quimica organometalica aplicada (QOA) E101Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): 1Funding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain

Start-End date: 2012 - 2012Total amount: 3.121 €

13 Name of the project: Grupo Emergente de Quimica organometalica aplicada (QOA) E101Entity where project took place: INSTITUTO DE SINTESIS QUIMICA Y CATALISIS HOMOGENEAName principal investigator (PI, Co-PI....): 1Funding entity or bodies:Gobierno de Aragón Type of entity: Publica

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City funding entity: Spain


14 Name of the project: Compuestos soluble en agua. Propiedades y aplicacionesEntity where project took place: Instituto de Cienciade Materiales de Aragón

Type of entity: University Research Institute

Name principal investigator (PI, Co-PI....): Mariano Laguna CastrilloFunding entity or bodies:C.I.C.Y.T.

FEDER (CTQ2008-06716-C03-01/BQU)


15 Name of the project: Avances en recubrimientos tecnológicos para aplicaciones decorativas (CENITARTDECO)Entity where project took place: INSTITUTO SINTESIS QUIMICA Y CATALISIS HOMOGENEAStart-End date: 01/01/2007 - 01/01/2010Total amount: 100.000 €

16 Name of the project: Grupo Consolidado de Química Inorgánica y de los Compuestos OrganometálicosEntity where project took place: Instituto de Ciencia de Materiales de AragónName principal investigator (PI, Co-PI....): Mariano Laguna CastrilloFunding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain


17 Name of the project: Avances en recubrimiento tecnológicos para aplicaciones decorativas (ART-DECO)Entity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano Laguna; Torrecid S.A. y AINFunding entity or bodies:Ministerio de Educación y Ciencia (CENIT)


18 Name of the project: Diseño racional y producción por láser de materiales nanoestructurados bajo criteriosmolecularesEntity where project took place: ICMA y CARBOQUIMICAName principal investigator (PI, Co-PI....): Edgar MuñozFunding entity or bodies:Gobierno de Aragón (PM028/2007)


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19 Name of the project: Grupo Consolidado de Química Inorgánica y de los Compuestos OrganometálicosEntity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): 1Funding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain


20 Name of the project: Propiedades y aplicación de compuestos de coordinación de los grupos 10-12Entity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano Laguna CastrilloFunding entity or bodies:C.I.C.Y.T. CTQ2005-08099-C03-01/BQU




Name principal investigator (PI, Co-PI....): Juan Forniés GraciaFunding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain






23 Name of the project: Recubrimientos nanoparticulados para la industria cerámica en condicionesenergéticas suavesEntity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano LagunaFunding entity or bodies:Ministerio de Ciencia y Tecnología (PETRI PTR1995-0768-OP)


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26 Name of the project: Vanguardia, tradición y nuevos desarrollos tecnológicos en la cerámica tradicionalaragonesaEntity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano LagunaFunding entity or bodies:Gobierno de Aragón (02/COOPERA/ES/1368)






28 Name of the project: Complejos con tiolatos polifuncionales, preparacion y estudio de sus aplicacionesEntity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano Laguna CastrilloNº of researchers: 8Funding entity or bodies:C.I.C.Y.T. (nº BQU2002-04090-C02-01).

Start date: 2002 Duration: 3 yearsParticipating entity/entities: Instituto de Ciencia de Materiales de Aragón

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Total amount: 87.450 €

29 Name of the project: Grupo Consolidado de Química Inorgánica y de los Compuestos OrganometálicosEntity where project took place: Instituto de Ciencia de Materiales de AragónName principal investigator (PI, Co-PI....): Juan Forniés GraciaFunding entity or bodies:Gobierno de Aragón Type of entity: PublicaCity funding entity: Spain

Start date: 2002Total amount: 34.770 €

30 Name of the project: Tiolatos polifuncionales como ligandos híbridos para la síntesis de arquitecturasmolecularesEntity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano Laguna CastrilloNº of researchers: 6Funding entity or bodies:C.I.C.Y.T. (nº PB98-0542).

Start date: 1999 Duration: 3 yearsParticipating entity/entities: Instituto de Ciencia de Materiales de AragónTotal amount: 59.880 €

31 Name of the project: Tiolato derivados de oro. Síntesis dirigida y estudio de sus propiedades.Entity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Mariano Laguna CastrilloNº of researchers: 4Funding entity or bodies:C.I.C.Y.T. (nº PB95-0140-A).

Start date: 1996 Duration: 3 yearsParticipating entity/entities: Instituto de Ciencia de Materiales de AragónTotal amount: 38.922 €

32 Name of the project: Síntesis, caracterización y propiedades de sólidos (cristalinos, cristales líquidos yfilms de L-B) conductores basados en aminotetratiafulvalenos y análogos organometálicos..Entity where project took place: Instituto de Cienciade Materiales de Aragón


Name principal investigator (PI, Co-PI....): Javier Garín TerceroNº of researchers: 4Funding entity or bodies:C.I.C.Y.T. (nº PB91-0932)..

Start date: 1991 Duration: 3 yearsParticipating entity/entities: Instituto de Ciencia de Materiales de Aragón

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R&D non-competitive contracts, agreements or projects with public or private entities

1 Name of the project: Preparación de compuestos de coordinación y/o organometálicos para aditivos depinturasDegree of contribution: ResearcherNº of researchers: 6Funding entity or bodies:FACI METALESTCity funding entity: Zaragoza

Start date: 01/10/2010 Duration: 7 monthsTotal amount: 32.450 €

2 Name of the project: Nanopartículas metálicas con aplicaciones industriales 2Degree of contribution: ResearcherNº of researchers: 6Funding entity or bodies:GRUPO SAMCA-COLOR ESMALTEC S.A.

Start date: 01/07/2010 Duration: 19 monthsTotal amount: 25.960 €

3 Name of the project: Nanopartículas metálicas con aplicaciones industrialesDegree of contribution: ResearcherNº of researchers: 6Funding entity or bodies:GRUPO SAMCA- COLORESMALTEC S.A.City funding entity: Zaragoza

Start date: 18/06/2009 Duration: 7 monthsTotal amount: 25,52 €

4 Name of the project: Compuestos de coordinación en procesos de decoraciónOTRI 2008/0213Degree of contribution: investigadorName principal investigator (PI, Co-PI....): Mariano LagunaParticipating entity/entities: Instituto de Ciencia de Materiales de Aragón ; Torrecid S.A.; UZFunding entity or bodies:TORRECID Type of entity: Business

Start date: 17/04/2008 Duration: 7 months - 15 daysTotal amount: 229.000 €

5 Name of the project: Metales preciosos para decoraciónName principal investigator (PI, Co-PI....): Mariano LagunaParticipating entity/entities: Instituto de Ciencia de Materiales de Aragón ; Torrecid S.A.; UZFunding entity or bodies:TORRECID Type of entity: Business

Start date: 2006 Duration: 1 yearTotal amount: 10.000 €

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6 Name of the project: Recubrimientos nanoparticulados para la industria cerámicaName principal investigator (PI, Co-PI....): Mariano LagunaNº of researchers: 5Participating entity/entities: Instituto de Ciencia de Materiales de Aragón ; Torrecid S.A.; UZFunding entity or bodies:TORRECID Type of entity: Business


7 Name of the project: Aplicación de la Síntesis Inorgánica a la industria cerámicaDegree of contribution: OTRIName principal investigator (PI, Co-PI....): Mariano LagunaNº of researchers: 5Participating entity/entities: Instituto de Ciencia de Materiales de Aragón ; Torrecid SA; UZFunding entity or bodies:Torrecid SA Type of entity: Business

Start date: 2002Total amount: 4.640.000 €

8 Name of the project: Vanguardia, tradición y nuevos desarrollos tecnológicos en la cerámica tradicionalaragonesa (02/COOPERA/ES/1368)Degree of contribution: INNOVAARAGONName principal investigator (PI, Co-PI....): Mariano Laguna y Germán de la FuenteParticipating entity/entities: Cañada (Gres de Aragón) S.A.; Instituto de Ciencia de Materiales de Aragón ;Taller Escuela de Cerámica de Muel; UZFunding entity or bodies:Gobierno de Aragón

Start date: 2002 Duration: 2 yearsTotal amount: 14.000 €

9 Name of the project: Preparación y propiedades de esmaltes para chapaDegree of contribution: I3PName principal investigator (PI, Co-PI....): Mariano LagunaParticipating entity/entities: Instituto de Ciencia de Materiales de Aragón ; UZ; Vitrex SAFunding entity or bodies:Vitrex SA Type of entity: Business

Start date: 2001 Duration: 2 yearsTotal amount: 3.800 €

10 Name of the project: Estudio de las características de esmaltes y normas de calidadDegree of contribution: I3PName principal investigator (PI, Co-PI....): Mariano LagunaParticipating entity/entities: Instituto de Ciencia de Materiales de Aragón ; UZ; Vitrex SAFunding entity or bodies:Vitrex SA


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Results

Industrial and intellectual property

Title registered industrial property: Patente. Tionato complejos de platino(II) de estequiometría [PtR(R’)(L)(L’)]n con actividad antitumoralInventors/authors/obtainers: A. Mendía, S. Miranda, E. Vergara, F. Mohr, E. Cerrada y M. LagunaEntity holder of rights: Universidad de ZaragozaNº of application: E-P200602695Country of inscription: SpainDate of register: 23/10/2006

Scientific and technological activities

Scientific production

Publications, scientific and technical documents

1 Ines Marmol; Javier Quero; M Jesus Rodriguez-Yoldi; Elena Cerrada. Gold as a possible alternative toplatinum-based chemotherapy for colon cancer. Cancers. 11, pp. 780 - 816. 2019.Type of production: Scientific paper Format: JournalCorresponding author: Yes

2 Ines Marmol; Pilar Castellnou; Raquel Alvarez; M Concepción Gimeno; M Jesus Rodriguez-Yoldi; Elena Cerrada.Alkynyl Gold(I) Complexes Derived from 3-hydroxyflavones as Multi-Targeted Drugs Against Colon Cancer.European J. Medicinal Chemistry. 176, pp. 123 - 133. Elsevier, 2019.Type of production: Scientific paper Format: JournalCorresponding author: Yes

3 Elena Atrian-Blasco; Elena Cerrada; Peter Faller; Mariano Laguna; Christelle Hureau. Role of PTA in theprevention of Cu(Amyloid-β) induced ROS formation and Amyloid-β oligomerisation in the presence of Zn.Metallomics. 11, pp. 1154 - 1161. 2019.Type of production: Scientific paper Format: JournalCorresponding author: No

4 Javier Quero; Silvia Cabello; Teresa Fuertes; Ines Marmol; Ruben Laplaza; Victor Polo; M Concepcion Gimeno;M Jesus Rodriguez-Yoldi; Elena Cerrada. Proteasome versus Thioredoxin Reductase Competition as PossibleBiological Targets in Antitumor Mixed Thiolate-Dithiocarbamate Gold(III) Complexes. Inorganic Chemistry. 57, pp.10832 - 10845. 2018.Type of production: Scientific paper Format: JournalCorresponding author: Yes

5 Ines Marmol; Javier Quero; Maria Virumbrales-uñoz; Cristina Sanchez-de-Diego; Luis Fernandez; Ignacio Ochoa;Elena Cerrada; M Jesus Rodriguez-Yoldi. Alkynyl gold(I) complex triggers necroptosis via ROS generation incolorectal carcinoma cells. J. Inorganic Biochemistry. 176, pp. 123 - 133. Elsevier, 2017.Type of production: Scientific paper Format: Journal

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Corresponding author: Yes

6 Ines Marmol; Cristina Sanchez-de-Diego; Alberto Pradilla; Elena Cerrada; M Jesus Rodriguez-Yoldi. ColorectalCarcinoma: A General Overview and Future Perspectives in Colorectal Cancer. Int. J. Molecular Sciences. 18, pp.197 - 236. 2017.Type of production: Scientific paper Format: JournalCorresponding author: No

7 Sonia Gascon; Elena Atrian-Blasco; M Jesus Rodriguez-Yoldi; Mariano Laguna; Elena Cerrada. Novel thiolategold(I) derivatives synergistic with 5-fluorouracil as potential selective anticancer agents in colon cancer. InorganicChemistry. 56, pp. 8562 - 8579. 2017.Type of production: Scientific paper Format: JournalCorresponding author: Yes

8 Elena García-Moreno; Alejandro Tomás; Elena Atrián-Blasco; Sonia Gascón; Eduardo Romanos; Mª JesusRodriguez-Yoldi; Elena Cerrada; Mariano Laguna. In vitro and in vivo evaluation of organometallic gold (I)derivatives as anticancer agents. Dalton Transactions. pp. 2462 - 2475. 2016.Type of production: Scientific paper Format: Journal

9 Asunción Luquin; Noelia Castillo; Elena Cerrada; Francisco L. Merchan; Julian Garrido; Mariano Laguna.Palladium(II) Complexes of the Hemilabile Pincer Ligand PPh(o-C6H4SMe)2 as Highly Active andRecyclableMizoroki–Heck Catalysts. European Journal of Organic Chemistry. pp. 789 - 798. 2016.Type of production: Scientific paper Format: Journal

10 Elena Atrian-Blasco; Sonia Gascón; Mª Jesus Rodriguez-Yoldi; Mariano Laguna; Elena Cerrada. Synthesis ofgold(I) derivatives bearing alkylated 1,3,5-triaza-7-phosphaadamantane as selective anticancer metallodrugs.European J. Inorganic Chemistry. DOI:10.1002/ejic.201, 2016.Type of production: Scientific paper Format: JournalCorresponding author: Yes

11 Ines Marmol; Cristina Sanchez-de-Diego; Sonia Gascón; Mª Jesus Rodriguez-Yoldi; Elena Cerrada. Theanticancer effect related to disturbances in redox balance on Caco-2 cells caused by an alkynyl gold(I) complex. J.Inorganic Biochemistry. 166, pp. 108 - 121. Elsevier, 2016.Type of production: Scientific paper Format: JournalCorresponding author: No

12 Ines Marmol; Cristina Sanchez-de-Diego; Sonia Gascón; Mª Jesus Rodriguez-Yoldi; Elena Cerrada. Theanticancer effect related to disturbances in redox balance on Caco-2 cells caused by an alkynyl gold(I) complex. J.Inorganic Biochemistry. 166, pp. 108 - 121. Elsevier, 2016.Type of production: Scientific paper Format: JournalCorresponding author: No

13 Mariano Laguna; Elena Cerrada; Mª Jesus Rodriguez-Yoldi; Eduardo Romanos; José A. García de Jalón; SoniaGascon; Elena García-Moreno. In vivo anticancer activity, toxicology and histopathological studies of the thiolategold(I) complex [Au(Spyrimidine)(PTA-CH2Ph)]Br. Anticancer Agents in Medicinal Chemistry. 15 - (6), pp. 773 -782. 2015.Type of production: Scientific paper Format: Journal

14 Mariano Laguna; Peter Faller; D. Testemale; A. Conte-Daban; Elena Cerrada; Elena Atrian. Copper(I) targeting inthe Alzheimer's disease context: a first example using the biocompatible PTA ligand. Metallomics. 7 (portada), pp.1229 - 1232. 2015.Type of production: Scientific paper Format: Journal

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15 Elena García-Moreno; Sonia Gascon; Elena Atrian; Mª Jesus Rodriguez-Yoldi; Elena Cerrada; MarianoLaguna. Gold(I) complexes with alkylated PTA (1,3,5-triaza-7- phosphaadamantane) phosphanes as anticancermetallodrugs. European Journal of Medicinal Chemistry. 79, pp. 164 - 172. 2014.Type of production: Scientific paper Format: Journal

16 Elena García-Moreno; Sonia Gascon; M.Jesus Rodriguez-Yoldi; Elena Cerrada and Mariano Laguna.S-Propargylthiopyridine Phosphane Derivatives As Anticancer Agents: Characterization and Antitumor Activity.Organometallics. 32, pp. 3710 - 3720. USA2013.Type of production: Scientific paper Format: Journal

17 Elena García-Moreno; Elena Cerrada; M. José Bolsa; Asunción Luquin; and Mariano Laguna. Water-SolublePhosphanes Derived from 1,3,5-Triaza-7-phosphaadamantane and Their Reactivity towards Gold(I) Complexes.European. J. Inorganic Chemistry. pp. 2020 - 2030. Alemania-2013.Type of production: Scientific paper Format: Journal

18 Elena Guerrero; Susana Miranda; Sebastian Lu?ttenberg; Nils Fro?hlich; Jan-Moritz Koenen; Fabian Mohr;Elena Cerrada; Mariano Laguna; and Ara?nzazu Mendía. trans-Thionate Derivatives of Pt(II) and Pd(II) withWater-Soluble Phosphane PTA and DAPTA Ligands: Antiproliferative Activity against Human Ovarian Cancer CellLines. Inorganic Chemistry. 52, pp. 6635 - 6647. USA2013.Type of production: Scientific paper Format: Journal

19 Susana Miranda; Elena Cerrada; Aránzazu Mend´?a; Mariano Laguna. P-C Bond cleavage in dppm derivatives:X-ray structure of [Pd2(?2-P,CPPh2CHPOPh2)(?2-dppm)Cl(PPh2Me)]. Inorg. Chem. Commun. 21, pp. 151 - 154.2012.Type of production: Scientific paper Format: Journal

20 Susana Miranda; Elena Cerrada; Asunción Luquín; Aránzazu Mendía; Mariano Laguna. Palladium and Platinumpyrimidine-2-thionate complexes with diphosphines. Polyhedron. 43, pp. 15 - 21. Suiza2012.Type of production: Scientific paper Format: Journal

21 Elena Vergara; Elena Cerrada; Catherine. Thiolato gold(I) complexes containing water-soluble phosphaneligands: a characterization of their chemical and biological properties. Dalton Transactions. 40, pp. 10927 - 10935.UK2011.Type of production: Scientific paper Format: Journal

22 Elena Vergara; Angela Casini; Francesca Sorrentino; Olivier Zava; Elena Cerrada; Maria Pia Rigobello; AlbertoBindoli; Mariano Laguna and Paul J. Dyson. Anticancer therapeutics that target selenoenzymes: synthesis,characterization, in vitro cytotoxicity and thioredoxin reductase inhibition of a series of gold(I) complexes containinghydrophilic phosphine ligands. ChemMedChem. pp. 96 - 102. UK2010.Type of production: Scientific paper Format: Journal

23 Elena Vergara; Elena Cerrada; Angela Casini; Olivier Zava; Mariano Laguna and Paul J. Dyson. AntiproliferativeActivity of Gold(I) Alkyne Complexes Containing Water-Soluble Phosphane Ligands. Organometallics. 29, pp. 2596- 2603. USA2010.Type of production: Scientific paper Format: Journal

24 N. Lardies; E. Cerrada; M. Laguna. Bis(1,2,3-thiadiazoles) as precursors in the synthesis of Bis(alkynethiolate)Gold(I) Derivatives. European J. Inorganic Chemistry. pp. 137 - 146. Alemania2009.Type of production: Scientific paper Format: Journal

25 E. Cerrada; A. Moreno; M. Laguna. S,C- and S,S-coupling via dithiolate transfer reactions from tin to nickelcomplexes. Dalton Transactions. pp. 6825 - 6835. UK2009.Type of production: Scientific paper Format: Journal

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26 P. J. Skabara; C. Pozo-Gonzalo; N. Lardies; E. Cerrada; M. Laguna; A. Luquin; S. J. Coles; M. B. Hurtshouse;R. W. Harrington; W. Clegg. Novel dithiolene complexes incorporating conjugated electroactive ligands. DaltonTransactions. pp. 3070 - 3079. UK2008.Type of production: Scientific paper Format: Journal

27 S. Miranda; E. Vergara; D. de Vos; E. Cerrada; A. Mendía M. Laguna and F. Mohr. Synthesis, characterization andin vitro cytotoxicity of some gold(I) and trans-platinum(II) thionate complexes containing water-soluble TPA andDAPTA ligands”. Inorganic Chemistry. 47, pp. 5641 - 5648. USA2008.Type of production: Scientific paper Format: Journal

28 E. Cerrada; N. Lardies; M. Laguna; I. Romeo; P. J. Skabara. " Synthesis and Properties of Alkynethiolate Gold(I)Complexes.”. Dalton Transactions. pp. 5329 - 5338. UK2007.Type of production: Scientific paper Format: Journal

29 A. Luquin; C. Elosúa; E. Vergara; J. Estella; E. Cerrada; C. Bariáin; I. R. Matías; J. Garrido; M. Laguna."Application of gold complexes in the development of VOC’s sensors. Gold Bulletin. 40, pp. 225 - 233. 2007.Type of production: Scientific paper Format: Journal

30 E. Vergara; S. Miranda; F. Mohr; E. Cerrada; E. R. T. Tienik; M. P. Romero; A. Mendía; M. Laguna. "Gold(I) andpalladium(II) thiolato complexes containing water-soluble phosphane ligands”. European J. Inorganic Chemistry.pp. 2926 - 2933. Alemania2007.Type of production: Scientific paper Format: Journal

31 N. Lardies; E. Cerrada; M. Laguna. " Synthesis of Heteroleptic Nickel(II) and Palladium(II) Dithiolenes ".Polyhedron. 25, pp. 2785 - 2790. Suiza2006.Type of production: Scientific paper Format: Journal

32 R. Aroz; F. Mohr; E. Cerrada; M. Laguna. "One-pot self assembly of trinuclear silver(I) clusters containingpropargyl alcohols and bis(diphenylphosphino)methane (dppm) ligands.". Polyhedron. 25, pp. 3066 - 3070.Suiza2006.Type of production: Scientific paper Format: Journal

33 F. Mohr; E. Cerrada; M. Laguna. "Organometallic gold(I) and gold(III) complexes containing1,3,5-triaza-7-phosphaadamantane (TPA): examples of water soluble organometallic gold compounds.".Organometallics. 25, pp. 644 - 648. USA2006.Type of production: Scientific paper Format: Journal

34 F. Mohr; E. Cerrada; M. Laguna. "Synthesis and coordination chemistry of an alkyne functionalisedbis(pyrazolyl)methane ligand”. Dalton Transactions. pp. 5567 - 5573. UK2006.Type of production: Scientific paper Format: Journal

35 F. Mohr; S. Sanz; E. Vergara; E. Cerrada; M. Laguna. "Water soluble and water stable gold(I), gold(II) andgold(III).". Gold Bulletin. 39, pp. 212 - 215. 2006.Type of production: Scientific paper Format: Journal

36 A. Mendía; E. Cerrada; M. Laguna; F. J. Arnáiz. Pyridine-2-thionate as Versatile Ligandin Pd(II) and Pt(II) Chemistry: Presence of three Different Coordination Modes in[Pd2(?1-S,-C5H4SN)2??2-S,N??1-S;?1-N),-C5H4SN)(?2-S(?2-S),-C5H4SN)????dppm)]. Dalton Transactions. pp.609 - 616. UK2006.Type of production: Scientific paper Format: Journal

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37 L. A. Mendez; J. Jiménez; E. Cerrada; F. Mohr; M. Laguna. A Family of AlkinylGolg(III) Complexes[Au(?-{CH2}2PPh2)2Au(C?CR)2] (R = Ph, t-Bu, Me3Si). Facile and Reversible Comproportionation ofGold(I)/Gold(III) to Digold(II). J. Americal Chemical Society. 127, pp. 852 - 853. USA2005.Type of production: Scientific paper Format: Journal

38 A. Luquín; C. Bariain; E. Vergara; E. Cerrada; J. Garrido; I. R. Matías; M. Laguna. New preparation of gold-silvercomplexes and optical fibre environmental sensors based on vapochromic [Au2Ag2(C6F5)4(phen)2]n. AppliedOrganometallic Chemistry. 19, pp. 1232 - 1238. University of IllinoisWiley-Interscience, 2005.Type of production: Scientific paper Format: Journal

39 A. Adé; E. Cerrada; M. Contel; M- Laguna; P. Merino; T. Tejero. Organometallic gold(III) and gold(I) complexesas catalyst for the 1,3-dipolar cycloaddition to nitrones: synthesis of novel gold-nitrone derivatives. J. OrganometChem.689, pp. 1788 - 1795. Suiza2004.Type of production: Scientific paper Format: Journal

40 P. Merino; T. Tejero; M; Laguna; E. Cerrada; A. Moreno; J. A: Lopez. An investigation of the Lewis acid mediated1,3-dipolar cycloaddition between N-benzyl-C(2-pyridil)nitrone and allylic alcohol. Direct entry to isoxazolidinylC-nucleosides. Org. Biomol. Chem. 1, pp. 2336 - 2342. 2003.Type of production: Scientific paper Format: Journal

41 C. Pozo-Gonzalo; R. Berridge; P.J. Skabara; E. Cerrada; S.J. Coles; M; Laguna; M. B. Hursthouse. A new familyof conjugated metallopolymers from electroplymerised bis(terthiophene dithiolene complexes. Chem. Commun. pp.2408 - 2409. UK2002.Type of production: Scientific paper Format: Journal

42 D.W. Allen; R. Berridge; N. Bricklebank; E. Cerrada; S.J. Coles; M. B. Hursthouse; M; Laguna; A. Moreno; P.J.Skabara. A new family of sulfur-rich ligands based on the dmit system: synthesis and metal complexation of4-4’-covalently bidged bis(2-thioxo-1,3-dithiol-5-thiolato) units. J. Chem. Soc. Dalton Trans. pp. 2654 - 2659.UK2002.Type of production: Scientific paper Format: Journal

43 A. Mendia; E. Cerrada; E.J. Fernandez; M; Laguna; A. Laguna. Four- Five and sis-coordinatedPentafluorophenylthallium(III) Complexes. Structures of [Tl(C6F5)3(OPPh3)], [Tl(C6F5)2Cl(OPPh3)]2 and[Tl(C6F5)2(OdppmO)2][Tl(C6F5)2Cl2]. J. Organomet Chem.663, pp. 289 - 296. Suiza2002.Type of production: Scientific paper Format: Journal

44 B. Villanueva Anadón; A. Ferrer Dufol; E. Civeira Murillo; I. Gutierrez Cia; M. Laguna Castrillo; E. CerradaLamuela. Intoxicación por metanol. Medicina Intensiva. 26(5), pp. 264 - 266. 2002.Type of production: Scientific paper Format: Journal

45 M. Cera; E. Cerrada; M. Laguna; J. A: Mata; H. Teruel. Orthometalated Phenylthiolate Brigging DinuclearPalladium(II) Complexes. X-ray structures of [Sn2(m-C6H4S)2(tBu)4] and [Pd2(?-C6H4S)(?-dppm)2Cl2].Organometallics. 21, pp. 121 - 126. USA2002.Type of production: Scientific paper Format: Journal

46 E. Cerrada; L. R. Falvello; M. B. Hursthouse; M. Laguna; A. Luquín; and C. Pozo-Gonzalo. PPh(2-C6H4S)2 asa Pincer Ligand in Nickel(II) and Palladium(II) Complexes. X Ray Structure of [Ni{PPh(C6H4S)2}(PPh2Me)],[Pd2(?-dppe){PPh(C6H4S)2}2] and [Ni{PPh(C6H4S)2}]2.European J. Inorganic Chemistry. pp. 826 - 833.Alemania2002.Type of production: Scientific paper Format: Journal

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47 E. Cerrada; C. Diaz; M. C. Diaz; M. B. Hursthouse; M; Laguna; M; E. Light. Tetrathiafulvalene-functionalizedphosphine as a coordinating ligand. X-Ray structures of (PPh2)4TTF and [(AuCl)4{(PPh2)4TTF}]. J. Chem. Soc.Dalton Trans. pp. 1104 - 1111. UK2002.Type of production: Scientific paper Format: Journal

48 P.Merino; S. Anoro; E. Cerrada; M. Laguna; A. Moreno; T. Tejero. Crystal and Molecular Structures ofN-benzyl-C-(2-pyridyl) nitrone and its ZnBr2 Complex. A Study of Their Reactivity. Molecules. 6, pp. 196 - 208.Suiza2001.Type of production: Scientific paper Format: Journal

49 M. Gómez; S. Jansat; G. Muller; G. Noguera; H. Teruel; V. Moliner; E. Cerrada; M.B. Hurtshouse. FirstDioxomolybdenum(VI) Complexes Containing Chiral Oxazoline Ligands: Synthesis, Characterization and CatalitycActivity. European Journal Inorganic Chemistry. pp. 1071 - 1076. Alemania2001.Type of production: Scientific paper Format: Journal

50 I. Rio; R. Terroba; E. Cerrada; M.B. Hurtshouse; M. Laguna; M. E. Light; A. Ruiz M.Heteronuclear ComplexesContaining {Au2R}, {Au2Ir} and {AuRi} Cores with a Dithiolate Ligand Bridging the Metal Centres-X-ray Structuresof [Au2Ir(?-S2C6H4)(cod)(PPh3)]BF4 and [AuIr(?-S2C6H3)(cod)(PPh3)]. European Journal Inorganic Chemistry.Alemania2001.Type of production: Scientific paper Format: Journal

51 J. Aznar; E. Cerrada; M. B. Hurtshouse; M. Laguna; C. Pozo; M.P. Romero. Heteronuclear tin(IV)-silver(I)complexes with phosphinothiolate ligands. X-ray structure of [AgSn(?-SC6H4PPh2)2Me2(PPh2Me)]CF3SO3.CH2Cl2. J. Organometallic Chemistry. 622, pp. 280 - 285. Suiza2001.Type of production: Scientific paper Format: Journal

52 E. Cerrada; C. Diaz; M. C. Diaz; M. Laguna; A. Sabater. New conducting co-ordination polymers containingM(dmit)2 links. Synthetic Metals. 119, pp. 91 - 92. Suiza2001.Type of production: Scientific paper Format: Journal

53 E. Cerrada; M. Laguna; I. Romeo; H. Teruel. Non symmetric dithiolenes and dithiolates. Synthesis andoptoelectronic properties. Synthetic Metals. pp. 817 - 818. Suiza2001.Type of production: Scientific paper Format: Journal

54 E. Cerrada; M. Laguna; M. B. Hursthouse; R. Terroba. Synthesis and characterisation of phosphinothiolate tin(IV)complexes. Crystal structure of [SntBu2(OPPh2C6H4S)(OH2)]ClO4.H2O. Polyhedron. 20, pp. 2863 - 2867.Suiza2001.Type of production: Scientific paper Format: Journal

55 E. Cerrada; M. Contel; T. Gelbrich; M. B. Hursthouse; M. Laguna; A. D. Valencia. A New, Simple Route to NovelGold Clusters; X-ray Crystal Structure of an Au6Ag Wheel with a Gold Rim. Angedwante Chemie. 112, pp. 2443 -2445. Alemania2000.Type of production: Scientific paper Format: Journal

56 A. Ferrer; L. Tomas; M. L. Tomas; E. Cerrada; M. Laguna. Diferencia en la concentración de etanol en suero ysangre total: correlación e implicaciones en el diagnóstico clínico y legal de la intoxicación etílica. Toxicología. 17,pp. 33 - 35. 2000.Type of production: Scientific paper Format: Journal

57 E. Cerrada; S. Elipe; M. Laguna; F. Lahoz and A. Moreno. Dithiolate and diselenolate tin complexes as ligandstransfer reagent towards other metals. Synthetic Metals. 102, pp. 1759 - 1760. Suiza1999.Type of production: Scientific paper Format: Journal

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58 E. Cerrada; J. Garrido; M. Laguna; N. Lardies; I. Romeo. Synthesis of new tertathiafulvalenes with aromaticsubstituents and related metallic ditiolene complexes. Synthetic Metals. 102, pp. 1709 - 1710. Suiza1999.Type of production: Scientific paper Format: Journal

59 E. Cerrada; M. Laguna; J. Bartolomé; J. Campo; V. Orera and P. G. Jones. Cation-radical Salts withOrganometallic Gold Anions. X-ray structure of [TTFPh]2[Au(C6F5)2]. Synthetic Metals. 92, pp. 245 - 251.Suiza1998.Type of production: Scientific paper Format: Journal

60 E. Cerrada; M. Laguna; F. Garcia; R. Terroba and M. D. Villacampa. Formation ofThiolene versus Dithiolene Species from TTBEO. Structures of [Au(ddtCO2Et)PPh3] and[Sn(ddtCO2Et)]. (TTBEO = 2,5,6,7-tetrathiabicicle[4.3.0]non-1(6)-eno-8-one; ddtCO2Et =3-(ethoxicarbonilthio)-5,6-dihidro-1,4-dithiin-3-thiolate. J. Chem. Soc., Dalton Trans. pp. 3511 - 3516. UK1998.Type of production: Scientific paper Format: Journal

61 E. Cerrada; M. Laguna and P. Sorolla. Gold Complexes with 2-selenoxo-1,3-dithiole-4,5-dithiolato. Polyhedron. 17,pp. 295 - 298. Suiza1998.Type of production: Scientific paper Format: Journal

62 E. Cerrada and M. Laguna. Heteroleptic Gold Complexes with 4,5-diselenolate-1,3-dithile-2-thione (C3S3Se22-,dsit). Canad. J. Chemistry. 76, pp. 1033 - 1037. Canada1998.Type of production: Scientific paper Format: Journal

63 E. Cerrada; M. Laguna and M. D. Villacampa. m?(2-thioxo-1,3-dithiole-4,5-dithiolato)-bis{[tris(p-methoxyphenyl)phosphine]-gold(I)}. Acta Cryst., C. C54, pp. 201 - 203. UK1998.Type of production: Scientific paper Format: Journal

64 M. Bardaji; E. Cerrada; P.G. Jones; A. Laguna and M. Laguna.Synthesis of Dinuclear Gold(I) and Gold(II)Complexes by Reaction of [Au2{??-(CH2)2PPh2}2 with protonic acids. J. Chem. Soc., Dalton Trans. pp. 2263 -2266. UK1997.Type of production: Scientific paper Format: Journal

65 E. Cerrada; M.C. Gimeno; A. Laguna; M. Laguna; V. Orera and P.G. Jones.Charge transfer salts with mono- anddi-nuclear Ylide gold(I) complexes. X-ray of [Au(CH2PPh3)2](TCNQ) (TCNQ=7,7',8,8'-tetracyanoquinodimethane).J. Organomet. Chemistry. 506, pp. 203 - 210. Suiza1996.Type of production: Scientific paper Format: Journal

66 E. Cerrada; P.G. Jones; A. Laguna and M. Laguna.Nine- and ten-membered diauracycles with the C3S52- ligand.Crystal structure of NBu4[Au2(?-C3S5)(??2-CH2PPh2CH2)]. Inorg. Chim. Acta. 249, pp. 163 - 168. Suiza1996.Type of production: Scientific paper

67 E. Cerrada; P.G. Jones; A. Laguna and M. Laguna.Synthesis and Reactivity of Heteroleptic Complexes of Goldwith 2-thioxo-1,3-dithiole-4,5-dithiolate (dmit). X-Ray structure of [Au2(?-dmit)(PPh3)2], NBu4[Au(dmit)(PPh3)] andPPN[Au(dmit)(C6F5)2]. Inorganic Chemistry. 35, pp. 2995 - 3000. USA1996.Type of production: Scientific paper Format: Journal

68 E. Cerrada; E. J Fernández; P.G. Jones; A. Laguna; M. Laguna; and R. Terroba.Synthesis and reactivity oftrinuclear dithiolate gold(III) complexes. X-ray structure of [Au(C6F5)(S2C6H4)(SC6H4SPPh3)]. Organometallics.14, pp. 5537 - 5543. USA1995.Type of production: Scientific paper Format: Journal

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69 E. Cerrada; E.J. Fernández; M.C. Gimeno; A. Laguna; M. Laguna; R. Terroba and M.D.. Villacampa.Synthesis ofdithiolate gold(III) complexes by dithiolate transfer reactions. X-Ray structure of [Au(C6F5)(S2C6H4)(PPh3)]. J.Organomet. Chemistry. 492, pp. 105 - 110. Suiza1995.Type of production: Scientific paper Format: Journal

70 E. Cerrada; A. Laguna; M. Laguna and P.G. Jones.New coordination modes of4,5-dimerapto-1,3-dithiole-2-thionate(2-) in polynuclear gold(I) complexes. Crystal structures of[Au3?m3-C3S5)(PPh3)3]ClO4 and [Au4(m-C3S5)2m-PPh2CH2PPh2)2]. J. Chem. Soc., Dalton Trans. pp. 1325 -1326. UK1994.Type of production: Scientific paper Format: Journal

71 E. Cerrada; M.C. Gimeno; J. Jiménez; A. Laguna; M. Laguna and P.G. Jones.Ylide Transfer reactions used forthe synthesis of di- and trinuclear gold complexes. X-Ray structure of [Au3(?2-CH2PPh2CH2)(PPh3)2](TCNQ)(TCNQ= 7,7',8,8'-Tetracyanoquinodimethane).Organometallics. 13, pp. 1470 - 1475. USA1994.Type of production: Scientific paper Format: Journal

72 P.J. Alonso; E. Cerrada; M.C. Gimeno; A. Laguna; M. Laguna and P.G. Jones..Bis(phosphine) gold derivativeswith 7,7',8,8'-Tetracyanoquinodimethane. X-Ray structure of [Au(PPh3)2]TCNQ.Synth. Metals. 55 - 57, pp. 1772 -1776. UK1993.Type of production: Scientific paper Format: Journal

73 E. Cerrada; M. Bryce and A.J. Moore.Highly funtionalised analogues of Tetrathiafulvalene. New9,10-bis(1,3-dithiol-2-ylidene)9,10-dihydrianthraceno donors. J. Chem. Perkin Trans 1. 1, pp. 537 - 538. UK1993.Type of production: Scientific paper Format: Journal

74 Elena Cerrada; Vanesa Fernandez-Moreira; M Concepcion Gimeno. Gold and platinum alkynyl complexes forbiomedical applications. Advances in Organometallic Chemistry. 57, pp. 227 - 258. Elsevier (Edited by Pedro J.Perez), 2019.Type of production: Book chapter Format: BookCorresponding author: No

75 A. Luquin; E. Cerrada; M. Laguna. Pentafluorophenyl gold complexes. Gold Chemistry. Applicactions and Futuredirections in the life Science. Capitulo de Libro. pp. 93 - 163. Wiley-VCH, 2009. ISBN -10: 3-527-32086-5/ISBN-13: 978-3-527-32086-8Type of production: Book chapter Format: Book

76 A. Mendía; E. Cerrada; M. Laguna. Trifluoromethanesulfonatosilver(I) derivatives. Inorganic Synthesis. 1, pp. 85 -91. University of IllinoisWiley-Interscience, 2004.Type of production: Book chapter Format: Book

77 E. Cerrada and M. Laguna. Reactivity of Diauracycles. A Way to Prepare Chains of Gold Atoms. Capitulo de libro.pp. 459 - 476. P. Braunstein,L. Oro and Raithby, 1999.Type of production: Book chapter Format: Book

78 E. Cerrada; J. Garín; M.C. Gimeno; A. Laguna; M. Laguna and P.G. Jones. Charge-tranfer salts fromorganometallic gold(I) and gold(III) complexes. Capitulo libro. 131, pp. 164 - 167. CambridgeA. J. Welch and S. K.Chapman, The Royal Society of Chemistry, 1993.Type of production: Book chapter Format: Book

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Works submitted to national or international conferences

1 Title of the work: Women in STEM by EuLes: A proyect to promote scientific vocations in girlsName of the conference: ICERI2018 (11th annual International Conference of Education, Research andInnovation)Corresponding author: NoCity of event: Sevilla,Date of event: 12/11/2018End date: 14/11/2018Ana Allueva-Pinilla; Jose Luis Alejandre-Marco; Raquel Trillo-Lado; M Teresa Lozano-Albalate; ConcepciónAldea-Chagoyen; I. Álvarez-Lanzarote; S. Bayarri-Fernández; M Jesus Rodriguez-Yoldi; L. Fuentes-Broto;Elena Cerrada; C. Gimeno-Gasca.

2 Title of the work: Combination of gold complexes and plant polyphenols triggers strong apoptotic cell deathon colorectal cancerName of the conference: IThe 2nd European PhD & PostDoc SymposiumCity of event: Copenhagen, DenmarkDate of event: 07/11/2018End date: 07/01/2018City organizing entity: DenmarkMª Jesus Rodriguez-Yoldi; Elena Cerrada; Carmen Anzin-Azpiluicueta; Javier Quero; Ines Marmol.

3 Title of the work: Novel combination of gold complex and polyphenols from r. Canina triggers strongapoptosis on colon cancer cellsName of the conference: IIIQUIMBIOCHIM. Congreso de Jóvenes Bioquímicos y QuimiterapéuticosCity of event: Albacete, SpainDate of event: 03/10/2018End date: 05/10/2018City organizing entity: SpainMª Jesus Rodriguez-Yoldi; Elena Cerrada; Carmen Anzin-Azpiluicueta; Javier Quero; Ines Marmol.

4 Title of the work: Gold(I) complexes derived from flavonoids as anticancer drugsName of the conference: XXXVI GEQO ORGANOMETALLIC Chemistry GroupCity of event: Zaragoza, SpainDate of event: 05/09/2018End date: 07/09/2018Ines Marmol; Pilar Castellnou; Raquel Alvarez; M Concepcion Gimeno; M Jesus Rodriguez-Yoldi; ElenaCerrada. "Presentacion de poster".

5 Title of the work: Gold(I) derivatives with fluorous and hydrocarbon appendages as potential anticanceragents under hyperthermiaName of the conference: XXXVI GEQO ORGANOMETALLIC Chemistry GroupCity of event: Zaragoza, SpainDate of event: 05/09/2018End date: 07/09/2018Adrian Alconchel; Franceso Ruighi; Sara Ortego; Ignacio Balbas; M Concepcion Gimeno; M JesusRodriguez-Yoldi; Elena Cerrada. "Presentacion de poster".

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6 Title of the work: Rational drug design: comparison of the anticancer effect of two gold complexes onCaco-2 cell lineName of the conference: 3II Congreso Nacional de Jovenes investigadores en BiomedicinaCity of event: Valencia, SpainDate of event: 23/11/2017End date: 24/11/2017Ines Marmol; Javier Quero; Sonia Gascon; Cristina Sanchez; M Jesus Rodriguez-Yoldi; Elena Cerrada."Presentacion de poster".

7 Title of the work: Rational Design in gold complexes: induction of apoptosis or necroptosis in colorectalcancer cellsName of the conference: 31st EFFoST International ConferenceCity of event: Sitges, SpainDate of event: 11/11/2017Javier Quero; Sonia Gascon; Cristina Sanchez; M Jesus Rodriguez-Yoldi; Elena Cerrada. "Presentacion deposter".

8 Title of the work: Film-shaped inorganic-organic hybrid polymers with biological propertiesName of the conference: X Reunión Científica de BioinorgánicaCity of event: Bilbao, SpainDate of event: 10/07/2017Elena Cerrada; M. Laguna; H. El Kaouit; L. Medinilla; M. Trigo; S. Vallejos; F. Garcia; J.M. Garcia; AranchaMendia. "Presentacion de poster".

9 Title of the work: Necroptosis-induced by alkynyl gold(I) complexName of the conference: 14th International Symposium on Applied Bioinorganic Chemistry (ISABC)City of event: Toulouse, FranceDate of event: 10/06/2017Cristina Sanchez; Sonia Gascon; Javier Quero; M Jesus Ridriguez-Yoldi; Elena Cerrada. "Flashpresentation".

10 Title of the work: Pro-oxidant activity of alkynyl gold(I) complex with Caco-2 cell lineName of the conference: 5th Symposium on Veterinary Sciences Zaragoza-Toulouse-MünchenCity of event: Zaragoza, SpainDate of event: 13/11/2016End date: 04/09/2014Organising entity: UZaragozaCristina Sanchez; Ines Marmol; Javier Quero; S. Gascon; E. Cerrada; M.J. Rodriguez-Yoldi.

11 Title of the work: Comunicación oral: Apoptotic mechanism of alkynyl gold(I) complexes in colorectalcancer carcinomaName of the conference: XXXVII SECF Congress (Sociedad Española de Ciencias Fisiológicas)City of event: Zaragoza, SpainDate of event: 03/11/2016End date: 04/09/2014Organising entity: UZaragozaCristina Sanchez; Ines Marmol; Jesus Osada; S. Gascon; E. Cerrada; M.J. Rodriguez-Yoldi. "Apoptoticmechanism of alkynyl gold(I) complexes in colorectal cancer carcinoma".

12 Title of the work: Comunicación oral:Targeting Thioredoxine reductase: use of alkynyyl gold complexes incolorectal cancer treatmentName of the conference: XXXVII SECF Congress (Sociedad Española de Ciencias Fisiológicas)

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City of event: Zaragoza, SpainDate of event: 03/11/2016End date: 04/09/2014Organising entity: UZaragozaCristina Sanchez; Ines Marmol; Jesus Osada; S. Gascon; E. Cerrada; M.J. Rodriguez-Yoldi.

13 Title of the work: ALKYNYL GOLD(I) DERIVATIVES AS SELECTIVE ANTICANCER DRUGSName of the conference: XXXIV GEQO CongressCity of event: Gerona, SpainDate of event: 07/09/2016End date: 04/09/2014Organising entity: Uniersidad de GeronaE. Cerrada; Cristina Sanchez; Ines Marmol; Pilar Castellnou; S. Gascon; M Concepción Gimeno; M.J.Rodriguez-Yoldi.

14 Title of the work: Use of water-soluble phosphanes and their metallic complexes for the treatment of cancerand Alzheimer’s diseaseName of the conference: II Simposio de Jóvenes Investigadores de la Sociedad Española de QuímicaTerapéuticaCity of event: Madrid, SpainDate of event: 12/06/2015End date: 04/09/2014Organising entity: CSICE. Atrián-Blasco; E. García-Moreno; S. Gascon; M.J. Rodriguez-Yoldi; P. Faller; C. Hureau; E. Cerrada; M.Laguna.

15 Title of the work: Alternative synthesis of layered semiconducting materialsName of the conference: MRS Fall MeetingCity of event: Boston, United States of AmericaDate of event: 30/11/2014J. Coleman; M. Laguna; E. Cerrada; E. Muñoz; A. Harvey; D. Danlon; A. Pokle; S. Mettel; C. Bakers; H.Petterson; E. McGuire; H. Nerl; A. Seral-Ascaso.

16 Title of the work: Cu(I) removal as a new therapeutic approach against Alzheimer’s diseaseName of the conference: French Group of BioInorganic ChemistryCity of event: Anglet, FranceDate of event: 01/09/2014End date: 04/09/2014E. Atrián-Blasco; A. Conte-Daban; E. Cerrada; M. Laguna; P. Faller; C. Hureau.

17 Title of the work: FUNCIONALIZACIÓN “A DEMANDA” DE TIONATOS PARA NUEVAS PROPIEDADESDE SUS COMPLEJOS CON Pt(II) Y Pd(II)Name of the conference: XXXIV REUNIÓN BIENAL DE LA REAL SOCIEDAD ESPAÑOLA DE QUÍMICA(RSEQ)Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Santander, SpainDate of event: 15/09/2013End date: 18/09/20131; Elena Guerrero; Ambros Almassy; H. Elkaoutit; Elena Cerrada; J. Pablos; F.C. García; J. M. García.

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18 Title of the work: Gold(I) complexes with optimum hydrophilic/lipophilic balance as anticancer drugsName of the conference: XII International Symposium on Inorganic BiochemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Wrockaw, PolandDate of event: 08/2013E. Atrián-Blasco; E. García-Moreno; S. Gascón; E. Cerrada; M.J. Rodríguez-Yoldi; M. Laguna.

19 Title of the work: In vitro antiproliferative activity of thionate platinum(II) and palladium (II)Name of the conference: International Symposia on Metals Complexes-ISMECType of event: ConferenceType of participation: 'Participatory - posterCity of event: Burgos, SpainDate of event: 06/2013Aranzazu Mendía; Elena Guerrero; Susana Miranda; Jan-Moritz Koe; Sebastian Lütternberg; Nils Frölich;Aranzazu Mendía; Fabian Mohr; Elena Cerrada; Mariano Laguna.

20 Title of the work: In vitro and in vivo antiproliferative activity of water-soluble gold(I) complexes with PTAderivativesName of the conference: International Symposia on Metals Complexes-ISMECType of event: ConferenceType of participation: 'Participatory - posterCity of event: Burgos,Date of event: 06/2013Elena Cerrada Elena; Elena García-Moreno; Atrian-Blasco; Sonia Gascón; María Jesús Rodríguez-Yoldi;Eduardo Romoanos; Mariano Laguna. 06/2013.

21 Title of the work: Complejos de oro con balance optimo hidrofilito/lipofilico y su aplicación comoanticancerígenosName of the conference: IX Simposio de Jóvenes InvestigadoresType of event: Conference Geographical area: NationalType of participation: 'Participatory - posterCity of event: Zaragoza, SpainDate of event: 11/2012Elena Atrian-Blasco; Elena Cerrada; Elena García-Moreno; Sonia Gascón; María Jesús Rodríguez-Yoldi;Mariano Laguna. 11/2012.

22 Title of the work: Propiedades anticancerígenas de compuestos de oroName of the conference: XXX GEQOType of event: ConferenceType of participation: 'Participatory - posterCity of event: Castellon,Date of event: 06/2012Mariano Laguna; Elena García-Moreno; Sonia Gascón; Elena Atrian; Elena Cerrada; María JesúsRodríguez-Yoldi. 06/2012.

23 Title of the work: Antiproliferative Activity of Gold (I) Complexes containing Water-Soluble PhosphaneLigandsName of the conference: V Internatinal Conference BIFI 2012. Protein Targert: Discovery of BioactivecompoundsType of event: ConferenceType of participation: 'Participatory - poster

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City of event: Zaragoza,Date of event: 02/2012Elena García-Moreno; Sonia Gascón; Elena Cerrada; María Jesús Rodríguez-Yoldi; Mariano Laguna.02/2012.

24 Title of the work: Water-soluble thiolato gold(I) complexes: A characterization of their chemical andbiological propertiesName of the conference: XIX EuCOMC. 19th EuCheMS International Conference on OrganometallicChemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Toulouse,Date of event: 07/2011Elena Vergara; Elena Cerrada; Elena García; Catherine Clavel; Angela Casini; Paul J. Dyson; MarianoLaguna. 07/2011.

25 Title of the work: Complejos de oro solubles en agua con fosfinas derivadas de1,3,5-triaza-7-phosphaadamantane (PTA)Name of the conference: IV Jornadas de Jóvenes Investigadores de Física y Química de Aragón.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Zaragoza,Date of event: 11/2010Elena García; Elena Cerrada; Mariano Laguna. 11/2010.

26 Title of the work: Síntesis y estudio de la actividad anticancerígena de alquino complejos de oro(I) confosfinas solubles en agua.Name of the conference: XXIII Reunión grupo especializado de Química OrganometálicaType of event: ConferenceType of participation: 'Participatory - posterCity of event: Huelva,Date of event: 09/2010E. Vergara; E. Cerrada; M. Laguna; P. J. Dyson.

27 Title of the work: Síntesis de complejos de oro(I) solubles en agua y estudio de su actividad citotóxicafrente a células cancerígenasName of the conference: XXXII Reunión Bienal de la RSEQType of event: ConferenceType of participation: 'Participatory - posterDate of event: 09/2009E. Vergara; E. Cerrada; M. Laguna; P. J. Dyson. "Oviedo". 09/2009.

28 Title of the work: New strategies in the synthesis of water soluble organometallic complexesName of the conference: Gold2009. New industrial Applications for GoldType of event: ConferenceType of participation: 'Participatory - posterCity of event: Heildelberg, GermanyDate of event: 07/2009E. Garcia; E. Cerrada; S. Schaëfer; M.J. Bolsa; A. Luquin; M. Laguna. 07/2009.

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29 Title of the work: PTA y sus derivados como entrada a la síntesis de complejos de oro y paladio solublesen aguaName of the conference: XXVI GEQOType of event: ConferenceType of participation: 'Participatory - posterCity of event: Santiago de Compostela,Date of event: 09/2008E. Cerrada; E. Garcia; R. Matute; E. Vergara; M. Laguna. 09/2008.

30 Title of the work: Water soluble metallic compounds.Name of the conference: CIAM WORKSHOP CATALYSYS IN AQUEOUS MEDIAType of event: ConferenceType of participation: 'Participatory - posterCity of event: Toulouse, FranceDate of event: 07/2007A. Luquin; S. Schaëfer; E. Cerrada; A. Mendía; M. Laguna. 07/2007.

31 Title of the work: Compuestos metálicos solubles en aguaName of the conference: IV simposium de investigadores jóvenes. RSEQ_Sigma-Aldrich.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Burgos,Date of event: 2007A. Luquin; S. Schaëfer; E. Cerrada; A. Mendía; M. Laguna. 2007.

32 Title of the work: Gold(I) and palladium(II) complexes soluble in water and their role as catalystsName of the conference: FIGIPAS Meeting in Inorganic ChemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Viena,Date of event: 2007E. Vergara; S. Sanz; E. Cerrada; A. Luquin; F. Mohr; A. Mendía; M. Laguna. 2007.

33 Title of the work: Gold(I) and platinum(II) complexes soluble in water and their role as catalyst.Name of the conference: 9th FIGIPAS MeetingType of event: ConferenceType of participation: 'Participatory - posterCity of event: Viena,Date of event: 2007E. Vergara; S. Sanz; E. Cerrada; F. Mohr; A. Mendía; A. Luquin; M. Laguna. 2007.

34 Title of the work: In vitro citotoxicity in human cancer lines of water soluble organometallic gold(I) andplatinum(II) thiolato complexesName of the conference: FIGIPAS Dalton Discussion 10: Application of metals in Medicine and HealthcareType of event: ConferenceType of participation: 'Participatory - posterCity of event: Durham,Date of event: 2007E. Vergara; S. Miranda; E. Cerrada; D. de Vos; F. Mohr; A. Mendía; M. Laguna. 2007.

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35 Title of the work: Application of Gold Complexes in the Development of VOC´s SensorsName of the conference: Gold 2006Type of event: ConferenceType of participation: Participatory - oral communicationCity of event: Limmerik, IrelandDate of event: 2006A. Luquin; C. Elosúa; E. Vergara; J. Estella; E. Cerrada; C. Bariáin; I. R. Matías; J. Garrido; M. Laguna.2006.

36 Title of the work: One-pot self assembly of trinuclear silver(I) alkyne clusters containing dppm or dppa(dppm = bis(diphenylphosphino)methane, dppa = bis(diphenylphosphino)amine) ligandsName of the conference: International Conference on Organometallic Chemistry ICOMC2006Type of event: ConferenceType of participation: 'Participatory - posterDate of event: 2006R. Aroz; E. Cerrada; F. Mohr; M. Laguna.

37 Title of the work: Coexistence of Pd(I) and deprotonated bis(diphenylphosphine)methane monoxidein [Pd2Cl(?2-C,P,-CHPPh2OPPh2)(?2-dppm)(PPh2Me)] as a consequence of the cleavage of dppm in[PdCl2dppm]Name of the conference: 8th FIGIPAS Meeting in Inorganic ChemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Atenas, GreeceDate of event: 2005A. Mendia; S. Miranda; E. Cerrada; F. J. Arnaiz; M. Laguna. 2005.

38 Title of the work: Making organometallic species water soluble: propargyl alcohols as ligands for gold(I)and silver(I) complexesName of the conference: Green Chemistry. A solution for the worldType of event: ConferenceType of participation: 'Participatory - posterCity of event: Almeria,Date of event: 2005R. Aroz; F. Mohr; E. Cerrada; M. Laguna. 2005.

39 Title of the work: Electropolimerización en ditioleno complejos con metales de transiciónName of the conference: XXII Reunión grupo especializado de Química OrganometálicaType of event: ConferenceType of participation: 'Participatory - posterCity of event: Ciudad Real,Date of event: 07/2004N. Lardies; E. Cerrada; M. Laguna; P. Skabara. 07/2004.

40 Title of the work: Novel aspects in Catalytic Activity of 11 Group Metal Complexes. Biphasis CatalysisName of the conference: 21st Century COE Internatinal Symposium on Nano-future Catálisis (ISNC)Type of event: ConferenceType of participation: Participatory - oral communicationCity of event: Tokyo,Date of event: 08/2003M. Laguna; M. Contel; E. Cerrada; R. H. Fish; L. Jones. 08/2003.

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41 Title of the work: Versatilidad de ligandos tiolato polifuncionales en la preparacion de compuestso conpropiedades predeterminadasName of the conference: XXIX Reunion Bienal de la Real Sociedad Española de QuimicaType of event: ConferenceType of participation: 'Participatory - posterCity of event: Madrid,Date of event: 07/2003A. Luquin; N. Lardies; E. Cerrada; M. Laguna. "S2P16". 07/2003.

42 Title of the work: The use of silver or gold derivatives to remove pyridine-2-thiolate from palladium(II) orplatinum(II) co-ordination spheres: a new pathway leading to interesting structural situationsName of the conference: Meeting in Inorganic ChemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Lisboa,Date of event: 06/2003A. Mendía; E. Cerrada; M. Laguna. "P262". 06/2003.

43 Title of the work: 1,3-dipolar cycloaddittions tonitrones catalysed by gold(III) complexesName of the conference: ICSHC 13. International Symposium on homegeneous catalysisType of event: ConferenceType of participation: 'Participatory - posterCity of event: Tarragona,Date of event: 09/2002E. Cerrada; M. Laguna; M. Contel; A.Ade; T. Tejero; P. Merino. 09/2002.

44 Title of the work: Bis(2-tioanisol)fenilfosfina como ligando pincer en complejos de niquel (II) y paladio (II)Name of the conference: XXI Reunión del Grupo Especializado de Química Organometálica.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: San Sebastián,Date of event: 07/2002Mª Asunción Luquin; Elena Cerrada; María Contel; Mariano Laguna. 07/2002.

45 Title of the work: New conducting coordination polymers containing M(dmit)2 linksName of the conference: ICSM’00: International Conference on Science and Technology of SyntheticMetalsType of event: ConferenceType of participation: 'Participatory - posterCity of event: Gastein,Date of event: 2000E. Cerrada; M. Laguna; M.C. Diaz; C. Diaz. 2000.

46 Title of the work: Pyridin 2-tionato complejos mono y polinucleares de paladio y platino Título:1,3,5-tris(isopropil)fenil (Trip) en la quimica de centros de oro(I) y niquel(II) Título: Diseño de ligandos condos unidades dmit interconectadas. Estudio frente a centros metálicosName of the conference: Reunión del Grupo Especilizado de Química OrganometálicaType of event: ConferenceType of participation: 'Participatory - posterCity of event: Valladolid,

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Date of event: 2000F. Ba; E. Cerrada; T. Gelbrich; M.B. Hurthouse; M. Laguna; A.D. Valencia. "PC04/ PC09/ PB29". 2000.

47 Title of the work: [Ag3(O3SCF3)(PPh3)3] en la síntesis de piridin 2-tionato derivados hetronucleares de Pty PdName of the conference: Reunión cinetífica plenaria de Química Inorgánica POSTER: [Ag3(O3SCF3)(PPh3)3] en la síntesis de piridin 2-tionato derivados hetronucleares de Pt y PdType of event: ConferenceType of participation: 'Participatory - posterCity of event: Bilbao AÑO: 2000,Date of event: 2000A. Mendía; M. Gutierrex; O. Quintana; E. Cerrada; M. Laguna. "P66". 2000.

48 Title of the work: Complexes with the potentially tri-dentate phsophinothiol ligand PhP(C6H4S-)2 Título:Carbon-sulfur and sulfur-sulfur coupling reactions in dithiolene nickel complexesName of the conference: XIIth FECHEMType of event: ConferenceType of participation: 'Participatory - posterCity of event: Lisboa, PortugalDate of event: 1999E. Cerrada; A. Moreno; M. Laguna; S. Elipe; F. Lahoz. "P150". 1999.

49 Title of the work: Intoxicación suicida por CloroformoName of the conference: XII CONGRESO ESPAÑOL DE TOXICOLOGIAType of event: Conference Geographical area: NationalType of participation: 'Participatory - posterCity of event: Granada,Date of event: 1999A. Ferrer; M. A. Suarez; C. León; M. Laguna; E. Cerrada. 1999.

50 Title of the work: Polyfuntional Nickel(II) thiolate complexesName of the conference: 5th EGIPS Meeting in Inorganicc ChemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Toulose, FranceDate of event: 1999M. Laguna; E. Cerrada; J. Garrido; A. Moreno; I. Romeo; H. Teruel. "PA60". 1999.

51 Title of the work: Fosfino tiolato complejos de estaño(IV) como precursores de derivados heteronuclearesTítulo: Reacciones de acoplamiento S-C y S-S en la transferencia de ditiolatos coordinados Título:Complejos Metal-Nitrona. Síntesis y reactividad frente a dipolarófilos y reactivos de Grignard Título: Síntesisde ditiolatos y tertatiafulvalenos sustituidos a partir de alquinotiolatos. Estudio de sus compuestos decoordinaciónName of the conference: Reunión del Grupo Especilizado de Química OrganometálicaType of event: ConferenceType of participation: 'Participatory - posterCity of event: Barcelona,Date of event: 1998I. Romeo; E. Cerrada; M. Laguna; J. Garrido; N. Lardies. "PB 60/ PC20/ PC13/ PC12". 1998.

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52 Title of the work: New structures and Properties of Polyfunctional Thiolate Gold ComplexesName of the conference: Organomet-Metals, Metals Complexes and CatalysisType of event: ConferenceType of participation: Participatory - oral communicationCity of event: Harbin, ChinaDate of event: 1998M. Laguna; E. Cerrada; I. Romeo. 1998.

53 Title of the work: Diferencia en la concentración de etanol en suero y sangre total: correlación eimplicaciones en el diagnóstico clínico y legal de la intoxicación etílicaName of the conference: XII Jornadas Toxicológicas EspañolasType of event: Conference Geographical area: NationalType of participation: Participatory - oral communicationCity of event: Zaragoza,Date of event: 1997A. Ferrer; M.L. Tomás; L. Tomás; A. Fernández; E. Cerrada; M. Laguna. 1997.

54 Title of the work: Nitrone Complexes of Silver(I) and Nickel(II)Name of the conference: XIIth FECHEM: Conference on Organometllic ChemistryType of event: ConferenceType of participation: 'Participatory - posterCity of event: Praga, Czech RepublicDate of event: 1997E. Cerrada; M. Laguna; P. Merino; P. Marchán; A. Moreno; T. Tejero. "PA137". 1997.

55 Title of the work: Thio- and selenolate gold complexes via transmetalation reactionsName of the conference: GDCh International Conference: Progress in the Science and Technology of GoldType of event: ConferenceType of participation: 'Participatory - posterCity of event: Hanau, GermanyDate of event: 1996M. Laguna; E. Cerrada; R. Terroba; E.J. Fernández; A. Laguna. "P25". 1996.

56 Title of the work: Diversas estrategias para la síntesis de conductores inorgánicosName of the conference: XV Reunión del Grupo Especializado de Química OrganometálicaType of event: ConferenceType of participation: 'Participatory - posterCity of event: Sevilla,Date of event: 1995presentación de 1 poster. "P127". 1995.

57 Title of the work: Synthesis and reactivity of trinuclear dithiolate gold(III) complexes. X-ray structure of[Au(C6F5)(S2C6H4)(SC6H4SPPh3)]Name of the conference: Third Greek-Italian-Portuguese-Spanish Meeting in Inorganic Chemistry (3rdGIPS)Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Senigalia, ItalyDate of event: 1995R. Terroba; E. Cerrada; E.J. Fernandez; P.G. Jones; A. Laguna; M. Laguna. "P83". 1995.

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58 Title of the work: Eigth- and Nine-Member Diauracycles: Synthesis and ReactivityName of the conference: XVIth International Conference on the Organometallic Chemistry.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Brighton, United KingdomDate of event: 1994M. Bardaji; E. Cerrada; A. Laguna; M. Laguna. 1994.

59 Title of the work: Synthèse de dithiolate complexes d’or(I) a travers de cinc dérivésName of the conference: IV Journee Grand Sud-OuestType of event: ConferenceType of participation: 'Participatory - posterDate of event: 1994R. Terroba; E. Cerrada; E.J. Fernandez; P.G. Jones; A. Laguna; M. Laguna. 1994.

60 Title of the work: Different coordination modes of dmit ligand in gold chemistry.Name of the conference: Latin-American Inorganic Chemistry Meeting.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Santiago de Compostela,Date of event: 1993E. Cerrada; P.G. Jones; A. Laguna; M. Laguna; R. Terroba. 1993.

61 Title of the work: Bis(phsphine)gold(I) derivatives with 7,7’8,8’-tetracyanoquinodimethane. X-Ray structureof [Au(PPh3)2]TCNQName of the conference: International Conference on Science and Technology ofSynthetic MetalsType of event: ConferenceType of participation: 'Participatory - posterCity of event: Göteborg,Date of event: 1992P. Alonso; E. Cerrada; J. Garín; Mc. Gimeno; P.G. Jones; A. Laguna; M. Laguna. "ET/G 25,S". 1992.

62 Title of the work: Charge-Transfer Salts from Organometallic Gold(I) and Gold(III) ComplexesName of the conference: International Conference on the Chemistry of the Copper and Zinc Triads.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Edimburgo, United KingdomDate of event: 1992M. Laguna; A. Laguna; J. Garín; E. Cerrada; M.C. Gimeno. 1992.

63 Title of the work: Dinuclear Dithiolate Gold(I) and Gold(III) Complexes.Name of the conference: XVth International Conference on Organometallic Chemistry.Type of event: ConferenceType of participation: 'Participatory - posterCity of event: Varsobia, PolandDate of event: 1992E. Cerrada; A. Laguna; M. Laguna; R. Terroba. 1992.

64 Title of the work: Ylide Transfer Reactions, a way to new types of Gold ComplexesName of the conference: Second italian-portuguese-spanish Meeting in Inorganic Chemistry.Type of event: Conference

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Type of participation: 'Participatory - posterCity of event: Alfa Mar, PortugalDate of event: 1992M. Bardaji; E. Cerrada; J. Jimenez; A. Laguna; M. LAguna. "MS12-1". 1992.

R&D management and participation in scientific committees

Organization of R&D activities

Title of the activity: XXXVI GEQO ORGANOMETALLIC Chemistry GroupType of activity: Organización de Congreso Geographical area: NationalConvening entity: Universidad de Zaragoza-ISQCHCity convening entity: Zaragoza,Start-End date: 05/09/2018 - 07/09/2018

Other achievements

Stays in public or private R&D centres

1 Entity: University of Southampton. Department ofChemistry


City of entity: Southampton, United KingdomStart-End date: 1999 - 1999 Duration: 1 monthGoals of the stay: Post-doctoralProvable tasks: Determinación de estructuras por difracción de rayos X

2 Entity: Department of Chemistry. University ofDurham. Centre for Molecular Electronics


City of entity: Durham, United KingdomStart-End date: 1992 - 1992 Duration: 3 monthsName of programme: Determinación de estructuras por difracción de rayos XGoals of the stay: DoctorateProvable tasks: Preparación y estudio de tetratiafulvalenos con sustituyentes metálicos

Obtained grants and scholarships

1 Name of the grant: Beca estanciaAims: Post-doctoralAwarding entity: ROYAL SOCIETY Type of entity: FoundationConferral date: 1999 Duration: 1 monthEnd date: 1999

2 Name of the grant: Beca doctoradoAims: Pre-doctoralAwarding entity: Gobierno de Aragón Type of entity: State agencyConferral date: 1991 Duration: 4 yearsEnd date: 1994

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3 Name of the grant: Beca estanciaAims: Pre-doctoralAwarding entity: CAI Type of entity: BusinessConferral date: 1992 Duration: 3 monthsEnd date: 1992

Periods of research activity

1 Nº of recognized periods: 1Geographical area: NationalCertifying entity: Ministerio de Ciencia e Innovación.Investigación

Type of entity: Ministerio

City certifying entity: SpainDate of recognition: 2014










Documents

CVN - ELENA CERRADA LAMUELA...Dra. Mª Jesús Rodríguez-Yoldi (Departamento de Farmacología y Fisiología, UZ) Dr. Peter Skabara (Strathclyde University, UK) Dr. Paul Dyson (École