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CV Module, Page 1 (12/2009)
PROTECTED WHEN COMPLETED
<~~ 13638-786674502 ~~>
CV ModuleThis page is for CIHR use only. It will not be included in the evaluation of your application for funding.
Personal Identification Number (P.I.N.)
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Have you previously applied to CIHR forfunding? Previous family name used
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SULLIVAN Robert
X
33004
Axe RSPSECentre de recherche du CHUQ (CHUL)
CANADA (G1V 4G2)
2705, boul Laurier, Bloc T1-49Québec, Québec
Axe RSPSECentre de recherche du CHUQ (CHUL)2705 boul. Laurier, Bloc T1-49Québec, QuébecCANADA (G1V 4G2)
X
X
X 19/07/1954
YES
YESYES
YESYES
YESYES
YES
Dr. Mr. X Mrs. Prof.Ms.
(418) 525-4444 #46104Office
(418) 654-2765
Office
Start Date End Date Start Date End Date
Start Date
Primary Affilliation NameLaval University
06/2002
Previous given name used
Robert SULLIVAN
CV Module, Page 2 (12/2009)<~~ 13638-786674502 ~~>
Expertise
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
Discipline Sub Discipline
Code Description Code DescriptionRank
gamete biology
spermatozoa
fertility
contraception
male reproductive tract
fertilization
infertility
reproduction
developmental biology
reproductive technology
88
106
REPRODUCTION AND DEVELOPMENT
GENITO-URINARY SYSTEM
Infertility Male
Urology
1202
1332
List up to ten (10) key words that best describe your expertise in research, instruments and technique.
Indicate and rank the disciplines that best correspond to your research interests. No additional pages may be added.
Robert SULLIVAN
CV Module, Page 3a (12/2009)<~~ 13638-786674502 ~~>
Academic Background - One additional page may be added
Degree Type Degree Name and Specialty Institution/Organization andCountry
Start date
(MM/YYYY)
Supervisor name Date receivedor expected
(MM/YYYY)
Indicate all university degrees obtained and those in progress (where applicable) starting with the most recent. If you hold a co-degree from more than one institution (e.g. under the Soutien aux cotutelles de these de doctorat agreement between Quebec andFrance) enter each institution separately. Do not enter honorary degrees here, they should be listed in the Distinctions section.
Also indicate research training, such as postdoctoral or fellowship training. Trainees only: also list undergraduate and graduateresearch training experience.
Postdoctorate
Doctorate(PhD)
Master's
Bachelor's
PostdoctoralReproduction
Doctor of PhilosophyReproduction
Master of ScienceReproduction
Bachelor of ScienceN/A
Ludwig InstituteCANADA
Université de MontréalCANADA
Université de MontréalCANADA
Université de MontréalCANADA
Alan Peterson
Gilles Bleau
Pierre Couillard
not applicable
01/1985
09/1980
05/1977
09/1974
01/1987
05/1984
06/1980
05/1977
Robert SULLIVAN
CV Module, Page 4a (12/2009)<~~ 13638-786674502 ~~>
Position Institution/Organization and Country Department/Division andFaculty/School
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(MM/YYYY)
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Starting with the most recent, indicate your current position, where applicable, and other academic and non-academic position(s)since the beginning of your university studies. For your current positions leave the end date blank. Additional pages will beaccepted.
Work Experience
Director
Full Professor
Director
Assistant Professor
Associate Professor
Assistant Professor
Researcher
Director
Centre Hospitalier Universitaire de QuébecCANADA
Laval UniversityCANADA
Centre Hospitalier Universitaire de QuébecCANADA
Laval UniversityCANADA
Laval UniversityCANADA
Université de MontréalCANADA
Hôpital Maisonneuve-RosemontCANADA
Hôpital Saint-LucCANADA
Reproduction, perinatal health and children'shealth Axe
MedecineObstet-gyneco
Reproduction Unit, CHUL Research Center
MedecineObstet-gyneco
MedecineObstet-gyneco
MedecineObstet-Gyneco
Research Center
IVF-andrology laboratory
06/2008
06/2002
01/2004
06/1998
07/1995
01/1991
01/1987
01/1987
06/2008
06/2002
06/1998
07/1995
01/1991
01/1991
Robert SULLIVAN
CV Module, Page 5a (12/2009)<~~ 13638-786674502 ~~>
Distinctions / Awards / Credentials
Starting with the most recent, indicate any recognitions received, including awards, fellowships, scholarships, licenses,qualifications, professional designation or credentials. Do not include Academic Appointments here, as they are detailed underWork Experience. Maximum 20 entries.
Name/Title and Type Institution/Organization and Country Effective Date
(MM/YYYY)
End Date
(MM/YYYY)
Specialty Total Amount
Robert SULLIVAN
CV Module, Page 6 (12/2009)<~~ 13638-786674502 ~~>
Patents and Intellectual Property Rights
PUBLICATIONS AND PRESENTATIONS
Record the total numbers of patents / copyrights in the following table.
Give the number of publications and presentations in the course of your career. Detailed information should be attached asspecified in the "Contributions - details" section.
OBTAINED APPLICATIONS UNDER PROCESS
Total individual Sub-total Total individual Sub-total
TOTAL PATENTSAND
INTELLECTUALPROPERTY
RIGHTS
0 4 4 0 0 0 4
Publications RefereedArticles
Books andMonographs
Proceedings / BookChapters / Contributions
to a collective work
Abstracts / Notes TOTALS
Already Published 91 1 4 64 160
Accepted or in the Press 1 0 0 0 1
161
Total collectiveTotal collective
64 Invited presentations
IN CIRCULATION IN PROGRESS
Total individual Sub-total Total individual Sub-total
TOTAL LITERARYAND ARTISTIC
WORKS
0 0 0 0 0 0 0
Total collectiveTotal collective
LITERARY AND ARTISTIC WORKS
Provide the number of literary and artistic works created in the course of your career. Detailed information should be attachedas specified in the "Contributions - details" section.
Robert SULLIVAN
CV Module, Page 7a (12/2009)<~~ 13638-786674502 ~~>
Name ofStudent
Supervisory Experience: To be completed by applicants requesting research trainees as part of their budget, salary support candidatesand proposed supervisors of trainees.
Indicate the number of graduate students and postdoctoral fellows that you currently supervise or co-supervise. CIHR defines supervisory experienceas the formal supervision or co-supervision of trainees. Enter zero (0) if not applicable.
Complete this form by listing the trainees that you have supervised/co-supervised (and are currently supervising/co-supervising) within thelast five (5) years. Additional pages may be added if necessary. * Flag those where you were/are the Primary Supervisor.
Master Doctoral Post-Doctoral 222
ProgramType
DatesSupportPeriod
From (MM/YYTo
(MM/YYYY)
Degreereceived orexpected
YearDegreeRec'd
(YYYY)
Research Project (Short title) Currentposition andInstitution
Belleannée,Clémence
Akintayo,Ayodélé
Aragon, JuanPablo
Bergeron, MarieEve
Caballero, Julieta
D'Amours,Olivier
Boudreau, Luc
Girouard, Julie
PostdoctoralFellow, PhD
GraduateStudent
GraduateStudent
GraduateStudent
PostdoctoralFellow, PhD
GraduateStudent
PostdoctoralFellow, HealthProfessional
GraduateStudent
08/2010
09/2009
09/2009
08/2009
08/2009
09/2008
10/2008
01/2004
Postdoctorate
Doctorate (PhD)
Master's
Master's
Postdoctorate
Doctorate (PhD)
Doctorate (PhD)
Sperm proteins acquired during epididymaltransit: targets for contraception and toolsfor infertility diagnostic
Invalidation génique d'une protéinespermatique impliquée dans le processus dela fécondation
Caractérisation des phosphodiestérases dansles liquides séminales et épididymaires
Analyse par micropuce d'ADN des effets dela cryptorchidie sur le testicule humain
Study of cholesterol membrane transporterin the bovine spermatozoa
Proteomic analysis of epididymal in bullswith different fertility scores
Effet de la cryptorchidie sur le profil desgènes sur le testicule humain.
Rôle des rafts dans la maturationépididymaire des spermatozoïdes
Postdoctoral fellow,CHUQ (CHUL)
Postdoctoral traning,UQTR
2009
02/2009
01/2009
*
*
*
*
*
*
*
*
Robert SULLIVAN
CV Module, Page 7b (12/2009)<~~ 13638-786674502 ~~>
Name ofStudent
Supervisory Experience: To be completed by applicants requesting research trainees as part of their budget, salary support candidatesand proposed supervisors of trainees.
Indicate the number of graduate students and postdoctoral fellows that you currently supervise or co-supervise. CIHR defines supervisory experienceas the formal supervision or co-supervision of trainees. Enter zero (0) if not applicable.
Complete this form by listing the trainees that you have supervised/co-supervised (and are currently supervising/co-supervising) within thelast five (5) years. Additional pages may be added if necessary. * Flag those where you were/are the Primary Supervisor.
Master Doctoral Post-Doctoral 222
ProgramType
DatesSupportPeriod
From (MM/YYTo
(MM/YYYY)
Degreereceived orexpected
YearDegreeRec'd
(YYYY)
Research Project (Short title) Currentposition andInstitution
Morin, Guillaume
D'Amours,Olivier
Gaudreault,Christian
Gagnon, Marie-Claude
Thimon,Véronique
Émond Édith
GraduateStudent
GraduateStudent
PostdoctoralFellow, PhD
GraduateStudent
PostdoctoralFellow, PhD
GraduateStudent
09/2002
09/2006
09/2007
09/2005
02/2006
01/2005
Doctorate (PhD)
Master's
Master's
Postdoctorate
Master's
Expression de la protéine PH-20
Proteomic analysis of epididymal proteins inbulls with different fertility scores
P25m knock-out mouse
Étude des Rafts dans les ovocytes demammifères
The effect of vasectomy on gene expressionof the human epididymis
Modulation de l'expression des gènes del'épididyme par les spermatozoïdes.
Foreignpostdoctoral,Monash Institute
Job search
Research assistant,Laval Univ
Professor, Univ.Martinique
Research assistant,Immucon inc.
2008
2008
2008
2007
12/2008
08/2008
04/2008
12/2007
10/2007
09/2007
*
*
*
*
*
Robert SULLIVAN
CV Module, Page 8a (12/2009)<~~ 13638-786674502 ~~>
Funds REQUESTED
List all sources of support applied for (including CIHR) as an applicant or as a co-applicant. Include the principal applicant's name,title of the proposal, funding source, program name, total amount requested (in Canadian dollars) and the period of the support.Indicate your role in the funding (principal applicant/project leader or co-applicant).
To (MM/YYYY)Support PeriodFrom (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
To (MM/YYYY)Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY)
To (MM/YYYY)Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY)
To (MM/YYYY)Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY)
Robert SULLIVAN
CV Module, Page 9a (12/2009)<~~ 13638-786674502 ~~>
Funds CURRENTLY HELD
List all sources of support currently held (including CIHR) as an applicant or as a co-applicant. Include the principal applicant'sname, title of the proposal, funding source, program name, total amount awarded (in Canadian dollars) and the period of thesupport. Indicate your role in the funding (principal applicant/project leader or co-applicant).
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Functions of epidymosomes in sperm maturation
Novel strategy to identify bull fertility markers
Sperm proteins acquired during the epididymal transit: functions and usefulness for diagnostic of man infertility
Beta counter for research in reproduction
Natural Sciences and Engineering Research Council of Canada (NSERC)
Natural Sciences and Engineering Research Council of Canada (NSERC)
Canadian Institutes of Health Research (CIHR)
Natural Sciences and Engineering Research Council of Canada (NSERC)
RGPIN - Discovery, individual
CRD
Operating
EQPEQ - Equipment, cat. 1
Principal Applicant
Principal Applicant
Principal Applicant
Principal Applicant
$250,000
$367,290
$381,551
$45,565
04/2010
05/2009
10/2008
04/2010
03/2015
04/2012
09/2011
03/2011
Robert SULLIVAN
CV Module, Page 10a (12/2009)<~~ 13638-786674502 ~~>
Funds HELD IN THE LAST FIVE YEARS
List all sources of support held in the last five years (including CIHR) as an applicant or as a co-applicant. Include the principalapplicant's name, title of the proposal, funding source, program name, total amount awarded (in Canadian dollars) and the period ofthe support. Indicate your role in the funding (principal applicant/project leader or co-applicant).
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Functions of epidymosomes in sperm maturation
Involvement of epithelial cadherin in the mechanism of protein from bovine epididymosomes to the sperm plasma membrane
Analyseur de fluorescence après blanchiment (FRAP)
Rotor package for Beckman floor model centrifuge
Natural Sciences and Engineering Research Council of Canada (NSERC)
Canadian Institutes of Health Research (CIHR)
Natural Sciences and Engineering Research Council of Canada (NSERC)
Natural Sciences and Engineering Research Council of Canada (NSERC)
Operating
International Scientific Exchange Program - Conicet
Equipment
Equipment
Richard, Francois J.
Tremblay, Jacques
Principal Applicant
Principal Applicant
Co-Applicant
Co-Applicant
$235,400
$4,500
$52,628
$26,658
04/2005
07/2008
03/2008
03/2008
03/2010
03/2009
03/2009
03/2009
Robert SULLIVAN
CV Module, Page 10b (12/2009)<~~ 13638-786674502 ~~>
Funds HELD IN THE LAST FIVE YEARS
List all sources of support held in the last five years (including CIHR) as an applicant or as a co-applicant. Include the principalapplicant's name, title of the proposal, funding source, program name, total amount awarded (in Canadian dollars) and the period ofthe support. Indicate your role in the funding (principal applicant/project leader or co-applicant).
Total Amount (CAN$)
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Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Evaluation of the contribution of prostaglandins in the regulation of male fertility and genital tract functions
A primate animal model for the development of a contraceptive strategy applicable to men.
Specialized strategies for optimizing the fertility of cryopreserved bovine semen.
Sperm proteins acquired during epididymal transit: targets for contraception and tools for infertility diagnosis.
Canadian Institutes of Health Research (CIHR)
Canadian Institutes of Health Research (CIHR)
Natural Sciences and Engineering Research Council of Canada (NSERC)
Canadian Institutes of Health Research (CIHR)
Operating
Operating
Operating-Ideas to innovation
Operating
Fortier, Michel A
Leclerc, Pierre
Co-Applicant
Principal Applicant
Co-Applicant
Principal Applicant
$118,320
$304,740
$294,480
$510,750
04/2007
04/2005
04/2005
04/2002
03/2009
03/2008
03/2007
03/2007
Robert SULLIVAN
CV Module, Page 10c (12/2009)<~~ 13638-786674502 ~~>
Funds HELD IN THE LAST FIVE YEARS
List all sources of support held in the last five years (including CIHR) as an applicant or as a co-applicant. Include the principalapplicant's name, title of the proposal, funding source, program name, total amount awarded (in Canadian dollars) and the period ofthe support. Indicate your role in the funding (principal applicant/project leader or co-applicant).
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
Total Amount (CAN$)
Principal Applicant / Project Leader Your Role
Funding Source Program Name
Title of Proposal
Support PeriodFrom (MM/YYYY) To (MM/YYYY)
2 dimension electrophoresis apparatus and image analyser
Les mécanismes moléculaires de la capacitation des spermatozoïdes de bovin
Natural Sciences and Engineering Research Council of Canada (NSERC)
Fonds Québécois de la Recherche sur la Nature et les Technologies (FQRNT)
Equipment
Team grant
Leclerc, Pierre Co-Applicant
Principal Applicant
$58,421
$180,000
04/2006
06/2003
12/2006
05/2006
Most significant contributions Sullivan, Robert
11 2010-09-15
1) Identification of a family of sperm protein synthesized by the epididymis: these proteins have been shown to be novel targets to develop immunocontraception in human and animal (pests or pets). This concept has been protected by a patent: “Acrosomal sperm protein and uses thereof”.
2) Description of membranous vesicles with unusual biophysical properties which are released in the
epididymal lumen by apocrine secretion. These vesicles that we have named “epididymosomes” interact with sperm surface and transfer selected proteins to the sperm surface. Some of these proteins have been shown to be GPI anchored. This is a novel mechanisms of membrane protein acquisition that is involved in acquisition by mammalian spermatozoa their fertilizing ability.
3) Description of sperm carbonyl reductase which plays different function depending of the status of
differentiation of the male gamete. This protein has been shown to have “moonlighting” properties, including affinity for the egg’s zona pellucida.
4) Description of gene expression modifications of the human epididymis under vasectomy and how
they can affect sperm biochemistry and fertilizing ability following vasovasostomy in men. This can explain the discrepancy between surgical success rate of vasectomy reversal and the recovery of fertility.
Activities and contributions Sullivan, Robert
12 2010-09-15
Committee membership Committee member – FRSQ, FRSQ-INSERM exchange program 2008- Committee member - American Society of Andrology, International affairs 2003- Committee member - CIHR, operating grant, endocrinology peer review panel 2003-2006 Committee member - Society for Study of Reproduction, sponsorship committee 2003-2005 Committee member - Local organizing committee, 38th annual meeting of Society for Study of Reproduction 2003-2005 Committee member - NSERC, discovery grant, integrative animal biology panel A 2002-2005 Committee member - Local organizing committee, International Congress Andrology 2001 Committee member - Local organizing committee, 7th Inter. Symposium Spermatology 1998
Academic responsibilities Director - Reproduction, perinatal health and children’s health Axes 2008- Director - Ontogeny and reproduction research unit, CHUL research center 2004-2008 Committee member - Graduate studies program (physio-endocr), Université Laval 2001- External reviewer for granting agencies (total of 15/year) CFI, CIHR, FQRNT, NSERC, WHO, Conseil de recherche en pêche et alimentation du Québec
External reviewer for peer review journal (number of articles reviewed) Asian Journal of Andrology (8), Biochemica Biophysica Acta (1), Biochemical Pharmacology (1) Biology of Reproduction (15), Fertility and Sterility (6), International Journal of Andrology (1) Journal of Andrology (7), Molecular Human Reproduction (10), Molecular Reproduction and Development (1), Proceedings of the National Academy of Science (1), Reproduction (5)
Editorial board Journal of Andrology Associate editor Human Reproduction
Interruptions and delays Sullivan, Robert
13 2010-09-15
None.
Patents and intellectual property rights Sullivan, Robert
14 2010-09-15
1. Sullivan R and Légaré C (2010)
Provisional application for patent. Detection of human cysteine-rich secretory protein (CRISP-1) in semen and medical application related thereof. Filed February 18, 2010, U.S.A. No. 61/257,639
2. D’Amours O and Sullivan R (2008)
Provisional application for patent. Sperm fertility biomarkers and uses thereof. Filed Sept 3, 2008, U.S.A. No. 273859.9
3. Sullivan R (1998)
Acrosomal sperm proteins and uses thereof. Filed June 2nd, 1998, U.S.A. No. 5,989,549
4. Sullivan R and Boué F (1997)
Marker of male infertility and/or fertility. Filed April 18, 1996, U.S.A., No. 08/634,340. Filed April 14, 1997, Europe No. 97 915 240.2
Publications list Sullivan, Robert
15 2010-09-15
Published refereed papers (student under my supervision are indicated in bold) 1. Frenette G, Girouard J, D’Amours O, Allard N, Tessier L, Sullivan R (2010). Characterization
of two distinct populations of epididymosomes collected in the intraluminal compartment of the bovine cauda epididymidis. Biol Reprod 83(3):473-80. NSERC
2. Legare C, Boudreau L, Thimon V, Thabet M & Sullivan R (2010). Vasectomy affects cysteine-rich secretory protein (CRISP1) expression along the human epididymis and its association with ejaculated spermatozoa following vasectomy surgical reversal. J Androl 2010 Apr 8, Epub ahead of print. CIHR
3. Morin G, Sullivan R, Laflamme I, Robert C & Leclerc P (2010). SPAM1 isoforms from two tissue origins are differentially localized within ejaculated bull sperm membranes and have different roles during fertilization. Biol Reprod, 82:271-281. NSERC
4. D’Amours O, Frenette G, Leclerc P, Sullivan R (2009). Proteomic comparison of detergent-extracted sperm proteins from bulls with different fertility indexes. Reproduction 139 (3): 545-56. NSERC
5. Lachance C, Fortier M, Thimon V, Sullivan R, Bailey JL, Leclerc P (2009). Localization of HSP60 and GRP78 in the human testis, epididymis and mature spermatozoa. Int J Androl 33 (1): 33-44 CIHR
6. Girouard J, Frenette G, Sullivan R (2009). Compartmentalization of proteins in epididymosomes coordinates the association of epididymal proteins with the different functional structures of bovine spermatozoa. Biol Reprod, 80:965-972. NSERC
7. Frenette G, Leclerc P, D'Amours O, Sullivan R (2009). Estrogen sulfotransferase is highly expressed along the bovine epididymis and is secreted in the intraluminal environment. J Androl, 30(5): 580-9. NSERC
8. Sasseville M, Gagnon MC, Guillemette C, Sullivan R, Gilchrist RB, Richard FJ (2009). Regulation of gap junctions in porcine cumulus-oocyte complexes: Contributions of granulosa cell contact, gonadotropins and lipid rafts. Mol Endocrinol 23(5): 700-710
9. Frenette G, Leclerc P, D'Amours O, Sullivan R (2009). Estrogen sulfotransferase is highly expressed along the bovine epididymis and is secreted in the intraluminal compartement. J Androl 30(5): 580-589.
10. Girouard J., Frenette, G., & Sullivan, R. (2009) Compartmentalization of proteins in epididymosomes coordinates the association of epididymal proteins with the different functional structures of bovine spermatozoa. Biol Repro 80: 965-972.
11. Lachance C., Fortier, M., Thimon, V., Sullivan, R., Bailey, J.L., & Leclerc, P.(2009) Localization of HSP60 and GRP78 in the human testis, epididymis and mature spermatozoa. Int J Androl 33(1): 33-44.
12. Thimon V, Calvo E, Koukoui O, Légaré C, & Sullivan R (2008) Effects of vasectomy on gene expression profiling along the human epididymis. Biol Reprod. 79: 262-73.
13. Reyes-Moreno C, Laflamme J, Frenette G, Sirard MA & Sullivan R (2008) Spermatozoa regulate cell proliferation and protein secretion of epidymal cells cultured at two different temperatures. Molec Reprod Dev 75: 512-520.
14. Girouard J, Frenette G & Sullivan R(2008) Seminal plasma proteins regulate the association of lipids and proteins within detergent-resistant membrane domains of bovine spermatozoa. Biol Reprod.78:921-31
15. Thimon V, Frenette G, Saez F, Thabet M, Sullivan R. (2008) Protein composition of human epididymosomes: a proteomic and genomic approach. Hum Reprod. 23:1698-707.
Publications list Sullivan, Robert
16 2010-09-15
16. Sullivan R, Frenette G, Girouard J (2007) Epididymosomes are involved in the acquisition of new sperm proteins during the epididymal transit. Asian J Androl 9: 483-492.
17. Sullivan R, Légaré C, Thimon V (2007) Effects of vasectomy on protein secretion and sperm maturation along the human epididymis. ANHP-ANIR 9: 43-49
18. Thimon V, Koukoui O, Calvo E, Sullivan R (2007) Region specific expression profiling along the human epididymis. Molec Hum Reprod 13: 691-704.
19. Moskovtsev SI, Jarvi K, Légaré C, Sullivan R, Mullen JBM (2007) Epididymal P34H protein detection in men evaluated for infertility. Fertil Steril 88:1455-57.
20. Lefebvre J, Fan J, Chevalier S, Sullivan R, Carmona E & Manjunath P (2007) Genomic structure and tissue-specific expression of human and mouse genes encoding homologs of major bovine seminal plasma proteins. Mol Hum Reprod. 13: 45-53.
21. Frenette G, Girouard J & Sullivan R (2006) Comparison between epididymosomes collected in the intraluminal compartment of the bovine caput and cauda epididymidis. Biol Reprod. 75 : 885-890.
22. Sullivan R, Légaré C, Villeneuve M, Foliguet B & Bissonnette F (2006) Levels of P34H, an epididymal originating sperm protein, as a predictor of conventional in vitro fertilization outcome. Fertil Steril. 85(5):1557-9.
23. Legare C, Thabet M, Gatti JL & Sullivan R (2006) HE1/NPC2 status in human reproductive tract and ejaculated spermatozoa: consequence of vasectomy. Mol Hum Reprod. 12:461-68.
24. Frenette G, Thabet M & Sullivan R (2006) Polyol pathway in human epididymis and semen. J Androl. 27(2):233-239.
25. Desrosiers P, C Legare, P Leclerc & R Sullivan (2006) Membranous and structural damage that occur during cryopreservation of human sperm may be time-related events. Fertil Steril. 85(6):1744-52.
26. Sullivan R, F Saez, J Girouard & G Frenette (2005) Role of exosomes in sperm maturation during the transit along the male reproductive tract. Blood Cells Mol Dis. 35(1):1-10.
27. Sullivan R, G Frenette & C Légaré (2005) Sécrétions apocrines et glandes annexes. Andrologie. 15(1):35-40.
28. Morin G, C Lalancette, R Sullivan & P Leclerc (2005) Identification of the bull sperm p80 protein as a PH-20 ortholog and its modification during the epididymal transit. Mol Reprod Dev. 71(4):523-34.
29. Frenette G, C Legare, F Saez & R Sullivan (2005) Macrophage migration inhibitory factor in the human epididymis and semen. Mol Hum Reprod. 11(8):575-585.
30. Dubé É, C Légaré, C Gaudreault & R Sullivan (2005) Contraceptive responses of female hamsters immunized with recombinant sperm protein P26h. Contraception. 72(6):459-67.
In press refereed article 1. Caballero J, Frenette G, Sullivan R (2010). Post-testicular sperm maturational changes in the
bull: important role of the epididymosomes and prostasomes". Veterinary Medicine International. In press Aug 6, 2010.
Publications list Sullivan, Robert
17 2010-09-15
Presentations as guest speaker 1. Sullivan R (2009). Consequences of vasectomy on gene expression along the human epididymis:
can it affect fertility recovery following surgical reversal? Argentinian Society of Andrology, Buenos Aires, Argentina, March.
2. Sullivan R (2009). The mechanisms of proteins acquisition by spermatozoa during their transit along the mammalian excurrent duct. Instituto de biologia y medicina experimental, Buenos Aires, Argentina, March
3. Sullivan R (2008). Principal cells’ apocrine secretion of epididymosomes and its function in sperm maturation. Mini Symposium: monitoring cell-cell communications in the epididymis. 41st meeting of Society for Study of Reproduction, Kona, Hawaï, May.
4. Sullivan R (2006). How spermatozoa acquire new proteins during the epididymal transit: Roles of apocrine secretion and epididymosomes. Seminar Queen's University, Dept. Anatomy and Cell Biology, Kingston, Ontario, December.
5. Sullivan R (2006). Human epididymal proteins: Regulation and interaction with spermatozoa. IVth
European Congress of Andrology, Toulouse, France, December.6. Sullivan R (2006). Epididymosomes are involved in the acquisition of new sperm proteins during
epididymal transit. 4th International Workshop on Epididymis, Auvergne, France, December.7. Sullivan R (2006). Maturation of spermatozoa in the epididymis: how do they acquire new
proteins? Monash Institute of Health Research, Melbourne, Australia, June. 8. Sullivan R (2006). La maturation épididymaire ou comment le spermatozoïde acquiert de nouvelles
protéines. INRS-Armand-Frappier, Montréal, Canada, March.9. Sullivan R (2005). The role of exosomes in sperm maturation during the transit along the male
reproductive tract. International Workshop on "Exosomes: biological significance. McGill University, Montréal, Canada, May.
10. Sullivan R (2005). La vasectomie: l'opinion d'un épididymologiste. 13e Rencontre Hivernale des Biologistes en Reproduction du Québec, Forêt Montmorency, Québec, March.
11. Sullivan R (2005). Rôle des sécrétions apocrines dans la maturation épididymaire des spermatozoïdes. Centre de recherche Guy Bernier, Université de Montréal, Québec, March.
Communications (student under my supervision are indicated in bold)
1. D’Amours O, Frenette G, Leclerc P, Sullivan R (2009). Sperm bull proteins associated with fertility
indexes. 9th International Congress of Andrology, Barcelona, Spain, March 7-10. 2. Boudreau L, Lebel MH, Imbeault A, Légaré C, Sullivan R, Thabet M (2009). Does the decrease in
sperm P34H correlates with the time elapse between vasectomy and vasovasostomy? 9th International Congress of Andrology, Barcelona, Spain, March 7-10.
3. Légaré C, Thimon V, Thabet M, Sullivan R (2009). Vasectomy influences expression of CRISP1 in human excurrent duct. American Society of Andrology, Philadelphia, USA, April 4-7.
4. Morin G, Laflamme I, Robert C, Sullivan R, Leclerc P (2009). Bull sperm Spam1 is involved in the sperm interaction with the zona pellucida during fertilization. XX North American Testis Workshop, Philadelphia, USA, April 1-4
5. Moskovtsev SI, Jarvi K, Légaré C, Sullivan R, Mullen BM (2007). The frequency of epididymal protein P34H deficiency in men evaluated for infertility. Amer Soc Repro Med, Washington, USA, Oct 13-17.
6. Morin G, Sullivan R, Leclerc P (2007). Localisation of p80, the bovine PH-20, on the sperm plasma and acrosome membrane. Amer Soc Androl, Tampa, USA, April 18-24.
7. Thimon V, Koukoui O, Calvo E, Sullivan R (2007). Effects of vasectomy on the gene expression pattern along the human epididymis. Amer Soc Androl, Tampa, USA, April 18-24.
8. Laflamme J, Chapdelaine P, Fortier MA, Sullivan R (2007). Immortalisation of bovine caput epididymal cells. Amer Soc Androl, Tampa, USA, April 18-24.
Publications list Sullivan, Robert
18 2010-09-15
9. Thimon V, Koukoui O, Calvo E, Sullivan R (2006). DNA microarray analysis of the human epididymis transcriptome. 4th International Workshop on Epididymis, Châtel Guyon, France, Decembre 4-7.
10. Girouard J, Frenette G, Sullivan R (2006). Involvement of lipid raft microdomains in bovine epididymal sperm maturation. 4th International Workshop on Epididymis, Châtel Guyon, France, Decembre 4-7.
11. Caballero J, Veiga MF, Fornes M, Sullivan R, Vazquez-Levin MH. (2006). Development of immunoreactivity towards epithelial cadherin during epididymal sperm maturation. Studies in bovine and murine models. Argentina Society of Biology, Argentina, Novembre.
12. Girouard J, Frenette G, Sullivan R (2006). Involvement of lipid raft microdomains in bovine epididymal sperm maturation. IVth International workshop on epididymis, Chatel-Guyon, France, December 4-7.
13. Thimon V, Koukoui O, Calvo E, Sullivan R (2006). Microarray analysis of the human epididymis transcriptone. IVth International workshop on epididymis, Chatel-Guyon, France, December 4-7.
14. Légaré C, M Thabet, JL Gatti & R Sullivan (2006). HE1 isoforms in human reproductive tract. American Society of Andrology/Annual Meeting, Chicago, IL., USA, April 9-14.
15. Girouard J, G Frenette & R Sullivan (2006). Lipid raft microdomains in bovine epididymal sperm maturation. Keystone Symposia, Steamboat Springs, CO, USA, March 23-27.
16. Emond E, G Frenette, C Légaré, C Reyes-Moreno & R Sullivan (2006). Evidence of differential expression of transcriptome and protein by the caput epididymal cells in the presence of mouse spermatozoa. Society for the Study of Reproduction, Omaha, NE, USA, July 29-Aug 1.
17. Morin G, R Sullivan & P Leclerc (2005). Rôle de la protéine spermatique PH-20 bovine dans les interactions avec l'ovule: caractérisation d'un anticorps polyclonal dirigé spécifiquement contre p80, l'orthologue bovine de PH-20. Regroupement de Recherche en Reproduction/Réunion Annuelle, Trois-Rivières, Quebec, November 21.
18. Morin G, R Sullivan & P Leclerc (2005). Epididymal maturation of the bull sperm PH-20 protein. Society for the Study of Reproduction/Annual Meeting, Québec, Quebec, July 24-27.
19. Morin G, R Sullivan & P Leclerc (2005). Maturation épididymaire de la protéine PH-20 bovine. Journée de la Recherche de la Faculté de Médecine de l'Université Laval, Université Laval, Mai 25.
20. Laflamme J, I Coté, J Lapointe, G Frenette, JF Bilodeau & R Sullivan (2005). The polyol pathway in the bovine oviduct: expression of the aldose reductase and sorbitol dehydrogenase. Society for the Study of Reproduction/Annual Meeting, Québec, Quebec, July 24-27.
21. Girouard J, G Frenette, J Leclerc & R Sullivan (2005). Effet de l'efflux de cholestérol sur l'intégrité des microdomaines rafts et sur la localisation membranaire de la P25b des spermatozoïdes bovins. Regroupement de Recherche en Reproduction/Réunion Annuelle, Trois-Rivières, Quebec, November 21.
22. Girouard J, G Frenette & R Sullivan (2005). Cholesterol depletion alters lipid rafts structure and the membrane localization of the spermatozoa-associated protein P25b. Society for the Study of Reproduction/Annual Meeting, Québec, Quebec, July 24-27.
23. Gagnon MC, J Girouard, R Sullivan & F Richard (2005). Les micros domaines membranaires (lipid rafts) chez les ovocytes porcins et bovins. Regroupement de Recherche en Reproduction/Réunion Annuelle, Trois-Rivières, Canada, November 21.
24. Frenette G, C Légaré, F Saez & R Sullivan (2005). Macrophage migration inhibitory factor in the human epididymis and semen and its potential role in sperm motility. ASA - American Society of Andrology/Annual Meeting, Seattle, WA, USA, March 30 - April 05.
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localised
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Robert C
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● E
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● T
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a horse, Farsh
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● S
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district o
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sustain
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alaka Munasin
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Indra A
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Jou
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