Curriculum Vitae Naohiro Terada, M ... - College of Medicine · Veterinary Medicine, University of Florida License: Japanese Medical License, Registration No. 260174 Professional

Naohiro Terada, M.D., Ph. D. April, 2018

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Curriculum Vitae

Naohiro Terada, M. D., Ph. D.

Education:

1981 Osaka University, Osaka, Japan, M. D. (Ph. D. Degree was awarded in 2001)

1981-1984 Rotating Resident, Osaka University Hospital etc., Osaka, Japan

1984-1985 Resident in Pediatrics, Osaka Children's Medical Center, Osaka, Japan

1985-1987 Staff in Pediatrics, Osaka Police Hospital, Osaka, Japan

1987-1989 Research Fellow in Pediatrics, Osaka University, Osaka, Japan (Mentor: Keisei Kawa-Ha)

1988-1989 Research Fellow in Oncogene Research, Osaka University, Osaka, Japan (Mentor: Takeo Kakunaga)

1989-1992 Research Associate in Pediatrics, National Jewish Medical and Research Center, Denver, Colorado

(Mentor: Erwin W. Gelfand)

Professional Appointments:

1992-1999 Assistant Faculty Member, Division of Basic Sciences, Department of Pediatrics, National Jewish

Center Medical and Research Center, Denver, Colorado

1994-1999 Adjunct Assistant Professor, Department of Pediatrics (Division of Hematology/Oncology),

Department of Immunology, University of Colorado, School of Medicine, Denver, Colorado

2000-2001 Assistant Professor (Tenure Track), Department of Pathology, Immunology and Laboratory

Medicine, University of Florida College of Medicine, Gainesville, Florida

2001-2010 Associate Professor (with Tenure), Department of Pathology, Immunology and Laboratory Medicine,

University of Florida College of Medicine, Gainesville, Florida

2010-date Professor (with Tenure), Department of Pathology, Immunology and Laboratory Medicine,

University of Florida College of Medicine, Gainesville, Florida

2010-date Visiting Professor, Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University

2013-date

2015-date

Adjunct Professor, Department of Molecular Pathology, Tokyo Medical University

Courtesy Affiliate Professor, Department of Small Animal and Clinical Sciences, College of

Veterinary Medicine, University of Florida

License:

Japanese Medical License, Registration No. 260174

Professional Service and Committees:

National Service

Organizer American Society for Cell Biology Summer Meeting, “Signal Transduction Determining the Fate of

Stem Cells” at Montana State University, Bozeman, MT (2003)

Associate Editor Laboratory Investigation (2003-2008)

Ad Hoc Member NIH Study Section, NIDCR, Special Emphasis Panel (ZDE1, RFA DE-05-005) (2004)

Ad Hoc Member NIH Study Section, NIAMS, Special Emphasis Panel (ZAR1) (2004)

Ad Hoc Member NIH Study Section, NINDS, Special Emphasis Panel (RFA NS-05-005) (2005)

Ad Hoc Member NIH Study Section, DEV2, Ad-Hoc (2005)

Member ISSCR 4th Annual Meeting Abstract Review Sub-Committee (2006)

Ad Hoc Member NIH Study Section, BTSS, Ad-Hoc (2007)

Ad Hoc Member NIH Study Section, Special Emphasis Panel (RG1-BDA-A (58)R) (2009)

Moderator Cardiac Regeneration/Cellular Therapy Scientific Session, American Heart Association,

Annual Meeting (2007)

Co-Director Southeast Stem Cell Consortium (2007-date)

Editorial Board Laboratory Investigation (2008-2011)

Vice Chair 1st Southeast Stem Cell Consortium Workshop (2008)


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Ad Hoc Member NIH Study Section, RFA OD09-003 Challenge Grant Panel #10 (ZRG1-BDA-A (58)R)

(2009)

Editorial Board Stem Cells (2009-date)


Chair 2nd Southeast Stem Cell Consortium Workshop (2009)

Ad Hoc Member NIH Study Section, Special Emphasis Panel (ZRG1 BDA-P (90) S) (2010)



Ad Hoc Member NIH Study Section, Special Emphasis Panel (CHHD-C Dev Biol) (2011)

Ad Hoc Member NIH Study Section, Special Emphasis Panel (WNPRC SEP) (2012)

Charter Member NIH Study Section, DEV2 (2013-2017)

Member Pharmacogenomics Research Network (PGRN) Steering Committee (2016-2017)

International Mentor Tokyo Medical University (2016-date)

Institutional Service

Member Admissions Committee, Interdisciplinary Program in Biomedical Sciences, University of

Florida College of Medicine (2000-2003)

Founding Member Program in Stem Cell Biology and Regenerative Medicine, University of Florida (2000-

present)

Reviewer Howard Hughes Medical Institute Research Support Program at University of Florida (2001-

2003)

Member Dean’s Advisory Committee for Future Research Development, University of Florida College

of Medicine (2003-2005)

Member Faculty Search Committee: Epigenetics, University of Florida College of Medicine (2004-

2006)

Member Institutional BIOSAFETY Committee, University of Florida (2009-2013)

Commencement Marshal University of Florida College of Medicine (2009-2011)

Director Center for Cellular Reprogramming, University of Florida (2010-date)

Member Committee for Postdoctoral Fellows, Junior Faculty Career Development, Division of

Experimental Pathology (2010-2011)

Reviewer UF internal selection process for the Searle Scholars Program (2011)

Secondary Mentor Mentoring Committee for Dr. Shin-ichi Someya, Department of Aging and Geriatric Research

(2012-2015)

Co-Primary Mentor Mentoring Committee for Dr. Anna-Maria Joseph, Pepper Scholar (2012-2015)

Member Faculty Search Committee, Pediatrics Hem/Onc, The faculty requisition #0903178 (2013)

Co-Mentor Mentoring Committee for Dr. Guangbin Xia, Department of Neurology (2016-2017)

Director Division of Experimental Pathology, Department of Pathology, Immunology and Laboratory

Medicine, University of Florida College of Medicine (2017-date)

Reviewer University of Florida Opportunity Fund (2018)

Societies/Membership:

American Association for the Advancement of Science (1994~)

American Society for Cell Biology (1999~)

International Society of Stem Cell Research (2002~)

Patents:

Co-Inventor, No. 5504093 "Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for

inhibition of DNA virus replication," issued on April 2, 1996

Co-Inventor, No. 5670520 “Method for inhibiting virus replication in mammalian cells using carbostyil derivatives,” issued

on September 23, 1997

Co-Inventor, No.7601525 “Novel tissue engineered scaffolds from copper capillary alginate gels,” issued on

October 13, 2,009


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Review and Referee Activities:

Associate Editor Laboratory Investigation (2003-2008)

Editorial Board Laboratory Investigation (2008-2011)

Editorial Board Stem Cells (2009-present)

Ad Hoc Reviewers Am J Pathol, Am J Physiol, Blood, Development, Exp Cell Res, EMBO J, EMBO R,

Epigenetics, FASEB J, Genes Dev, Gene Therapy, Hepatology, Hypertension, J Biol Chem,

Mech Dev, Mol Cell Biol, Nat Biotech, Nat Cell Biol, Nat Commun, Oncogene, PNAS, PLoS

Biol, Stem Cells, Trends Biotech, Trends Mol Med, etc.

Invited Presentations:

2018/3 Symposium Speaker, UF Regenerative Medicine Conference, Orlando, FL

2018/1 Session Speaker, World Stem Cell Summit, Miami, FL

2017/10 Invited Seminar, Shands Cancer Center, University of Florida

2017/10 Invited Seminar, Reproductive and Perinatal Biology Research Program, University of Florida

2017/9 Invited Seminar, Tokyo Medical University, Tokyo, Japan

2017/6 Invited Seminar, Tokyo Medical and Dental University, Tokyo, Japan

2017/3 Invited Seminar, Yale University, New Haven, CT

2017/3 Invited Seminar, Santa Fe College, Gainesville, FL

2017/1 Invited Seminar, MD/PhD Monthly Educational Dinner, University of Florida

2016/11 Invited Seminar, Nankai University, Tianjin, China

2016/10 Invited Webinar, PGRN RIPS

2016/9 Invited Seminar, Department of Anatomy & Cell Biology, University of Florida

2016/7 Invited Seminar, Cleveland Clinic, Cleveland, OH

2016/6 Speaker, Biomedical Explorations Bench to Bedside, Gainesville, Florida




2016/2 Invited Plenary Lecture, Kinki Pediatric Hematology/Oncology Society, Osaka, Japan

2015/12 Invited Seminar, Department of Aging, University of Florida

2015/11 Invited Seminar, Otsuka Pharmaceutical Inc, Tokushima, Japan

2015/10 Invited Seminar, Department of Physiology, University of Florida

2015/6 Speaker, Biomedical Explorations Bench to Bedside, Gainesville, Florida


2015/1 Invited Seminar, Osaka City University, Osaka, Japan

2015/1 Invited Seminar, National Research Institute for Child Health and Development, Tokyo, Japan

2014/11 Invited Seminar, Department of Biochemistry, University of Florida

2014/11 Invited Seminar, Medical College of Georgia, Georgia Regents University, Augusta, GA


2014/4 Invited Seminar, University of North Carolina, Chapel Hill, NC

2014/1 Invited Seminar, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan


2013/12 Invited Seminar, Shands Cancer Center, University of Florida


2012/11 Symposium Speaker, U01/U54 Contraception Meeting – Baylor College of Medicine – Houston, TX

2012/10 Invited Seminar, Veterinarian Physiological Sciences Seminar, University of Florida

2012/6 Invited Seminar, Otsuka Pharmaceutical Inc, Tokushima, Japan

2012/3 Invited Seminar, Animal Molecular and Cell Biology, University of Florida

2011/11 Invited Seminar, Ehime University, Matsuyama, Japan

2011/11 Invited Seminar, Hyogo University of Health Sciences, Kobe, Japan

2011/11 Invited Seminar, Nankai University, Tianjin, China

2011/11 Invited Seminar, Cha University, Seoul, Korea

2011/11 Invited Seminar, Gachon University, Incheon, Korea

2011/9 Invited Seminar, Otsuka Maryland Research Institute, Rockville, MD


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2010/10 Keynote Speaker, International Conference on Systems Biology of Stem Cells, Taipei, Taiwan

2010/7 Invited Symposium Speaker, 3rd Southeast Stem Cell Consortium Workshop, Nashville, TN

2010/3 Invited Seminar, National Research Institute for Child Health and Development, Tokyo, Japan



2009/11 Invited Seminar, Hyogo University of Health Sciences, Kobe, Japan

2008/12 Invited Seminar, University of Colorado, Department of Pediatrics, Denver, CO

2008/10 Invited Symposium Speaker, 1st Southeast Stem Cell Consortium Workshop, Athens, GA

2008/4 Invited Seminar, University of Illinois, Urbana-Champaign, IL


2007/3 Invited Seminar, Otsuka Pharmaceuticals, Otsu, Japan


2006/9 Invited Seminar, University of Washington, Seattle, WA

2006/9 Invited Seminar, Animal Molecular and Cell Biology, University of Florida


2006/2 Invited Symposium Speaker, Keystone Symposium, Santa Fe, NM

2005/12 Invited Symposium Speaker, Florida Genetics 2005

2005/6 Invited Symposium Speaker, Teratology Society, St. Pete, FL

2005/5 Invited Symposium Speaker, American Transplantation Congress, Seattle, WA

2005/3 Invited Seminar, Kyushu University, Fukuoka, Japan

2005/1 Invited Symposium Speaker, Forefront in Nephrology “Stem Cell and Regeneration of the Kidney”,

Karuizawa, Japan

2003/10 Invited Plenary Lecture, Annual Meeting, Korean Society of Medical Biochemistry and Molecular

Biology, Seoul, South Korea

2003/8 Invited Symposium Speaker, American Heart Association Summer Conference “Molecular Mechanisms

of Growth, Death, and Regeneration in the Myocardium: Basic Biology and Insights into Ischemic Heart

Disease and Heart Failure” Snowbird, UT

2003/5 Invited Symposium Speaker, 11th International Symposium “Recent Advances in Hematopoietic Stem

Cell Transplantation”, San Diego, CA

2003/4 Invited Symposium Speaker, Annual Meeting, American Society for Physiology, FASEB Experimental

Biology Meeting, San Diego, CA

2003/3 Invited Plenary Lecture, Annual Meeting, Canadian Society for Transplantation, Lake Louise, Alberta,

Canada

2002/11 Invited Symposium Speaker, 35th Annual Meeting, American Society for Nephrology, Philadelphia, PA

2002/10 Invited Symposium Speaker, 25th Annual Meeting, Japanese Society for Hematopoietic Cell

Transplantation, Osaka, Japan

2002/10 Invited Symposium Speaker, 75th Annual Meeting, Japanese Society of Biochemistry, Kyoto, Japan

2002/10 Invited Symposium Speaker, 2nd Annual Stem Cells & Regenerative Medicine, Strategic Research

Institute, San Diego, CA

2002/9 Invited Symposium Speaker, Functional Proteomics: Advanced technologies for the analysis of cell

function, Tokyo, Japan


2002/6 Invited Seminar, University of Colorado, Department of Medicine, Denver, CO

2002/4 Invited Seminar, College of Medicine Research Day “Controversies in Medicine” Seminar, Gainesville, FL

2002/3 Invited Seminar, University of Colorado, Department of Pharmacology, Denver, CO

Research Interests:

Pluripotent Stem Cell Biology: Self-Renewal, Differentiation, Reprogramming and Application

Mitochondrial Adenine Nucleotide Translocase (ANT): Differential Function of ANT paralogs in Development

and Diseases

Teaching Activities:

Class Lectures:

2017-date Lecturer - BME6330 “Cell and Tissue Engineering”


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2015-date Lecturer - GMS 6001 “Fundamentals of Biomedical Science I”

2013-2015 Lecturer - ANS 6751 “Physiology of Reproduction”

2013-date Lecturer - “Introduction to Stem Cells” (Tokyo Medical University)

2012-date Lecturer - GMS 6421 “Advanced Cell Biology”

2009-2013 Lecturer - ZOO 3603 “Evolutionary Developmental Biology”

2008-2010 Lecturer - GMS 6005 “Fundamentals of Developmental Biology”

2005-date Lecturer - BCH 7412 “Epigenetics of Human Diseases and Development”

2002-date Course Director - GMS 6331 “Basic Stem Cell Biology”

2000-2006 Discussion Leader - POPS at General Pathology and Immunology (for Medical Students) at U. Florida

2001-2003 Lecturer at Ground Rounds - GMS 6005 (Section 7) “Developmental Biology”

Discussion Leader - GMS 6005 (Section 7) “Developmental Biology”

Discussion Leader - GMS 6006 (Section 8) “Immunology & Microbiology”

1994-1995 Lecturer - Graduate Student Immunology Courses (IDPT 7662, 7663), "The Cell Biology of the Immune

System," Department of Immunology, University of Colorado Health Sciences Center

1996-1999 Lecturer - Basic Science Course, "Introduction to Cell Biology," Department of Pediatrics, University of

Colorado Health Sciences Center

Awards for Trainees (during their training period or for their studies accomplished in Terada’s lab.):

2017 Natalie Fredette, Experimental Pathology Innovative Grant

2016-2017 Natalie Fredette, CTSI, Non-Patient Pilot Award

2016 Joonseok Cho, Exemplary Graduate Student Award, Department of Pathology

2016 Joonseok Cho, 1st Place (Health Science), Florida Statewide Graduate Student Research Symposium

2016 Natalie Fredette, UF Postdoc Research Symposium, Best Poster Award

2016 Joonseok Cho, Finalist (Silver Award), 41st Annual Medical Guild Graduate Student Research Competition

2016 Di Xia, University of Florida, University Scholars Program Award

2015 Joonseok Cho, 21st Annual Outstanding International Student Award, University of Florida

2015 Joonseok Cho, Graduate Scholarship Award, Korean-American Scientists Engineers Association, GFC

2015 Natalie Fredette, Experimental Pathology Innovative Grant

2015-2017 Natalie Fredette, NIH Training Grant (T32), postdoc, DK074367

2015 Katherine Santostefano, University of Florida Superior Accomplishment Award

2014 Joonseok Cho, Graduate Scholarship Award, Korean-American Scientists Engineers Association, KUSCO

2014 Nikolett Biel, CTSI, Pilot Project Award

2014 Anastasiya Yakovenko, Accepted in Junior Honors Medical Program

2014 Nikolett Biel, UF Postdoc Research Symposium, Best Poster Award

2014 Bayli DiVita, University of Florida, University Scholars Program Award

2013 Crysta Iv, Accepted in Junior Honors Medical Program

2012 Aline Bonilla, Experimental Pathology Innovative Grant

2011 You-Jin Jang, University of Florida, HHMI Science for Life Award

2011 You-Jin Jang, University of Florida, University Scholars Program Award

2010 Aline Bonilla, Experimental Pathology Innovative Grant

2010 Ken-ichi Shinohara, Experimental Pathology Innovative Grant

2010 Paola Esparragoza, University of Florida, University Scholars Program Award

2009-2010 Takashi Hamazaki, P01 GM085354 (Dalton, PI), pilot project grant

2009 Jeff Brower, Lawrence M. Goodman Summer Research Fellowship

2009-2011 Katherine Hankowski, NIH Training Grant (T32), pre-doc, CA009126

2008 Takashi Hamazaki, Experimental Pathology Innovative Grant

2008 Rebecca Kirschner, American Cancer Society, Summer Research Fellowship

2008 Amy Rosenbluth, University of Florida, University Scholars Program Award

2008 Jeff Brower, Finalist (2nd Prize), 33rd Annual Medical Guild Graduate Student Research Competition

2007 Sarah Kehoe, American Society for Cell Biology (ASCB) Predoctoral Travel Award

2007 Katherine Hankowski, Research Incentive Award, UFCOM

2006 Amar Singh, Finalist (3rd prize), 31st Annual Medical Guild Graduate Student Research Competition

2005-2007 Brad Willenberg, NIH Training Grant (T32), post-doc, CA009126

2005 Nemanja Rodic, Keystone Symposium Scholarship

2004-2006 Amar Singh, AHA Predoctoral Fellowship

2004-2005 Jamie Graddy, American Cancer Society R. G. Thompson Memorial Summer Research Fellowship


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2003-2004 Amar Singh, NIH Training Grant (T32), pre-doc, AG00196-15

2003-2005 Jamie Graddy, University of Florida, University Scholars Program Award

2002-2003 Namanja Rodic, Alec Courtelis International Student Academic Award

2001-2002 Pete Piacenti, University of Florida, University Scholars Program Award

2001-2002 Takashi Hamazaki, American Liver Foundation, Postdoctoral Research Fellowship Award

1999 Tetsuo Minamino, American Heart Association, Finalist of Melvin Marcus Young Investigator Awards of

72nd Scientific Sessions (Atlanta)

1998-1999 Tetsuo Minamino, Banyu-Merck, Fellowship Awards in Lipid Metabolism and Atherosclerosis

Postdoctoral Fellows Education:

2018-date Jared Taylor, PhD

2016-2018 Chul Han, PhD currently Postdoc at Dignity Health, Phoenix, AZ

2016-2016 Yohei Tanada, MD/PhD currently Postdoc at King’s College, London

2016-2017 Noriko Watanabe, MD/PhD currently Associate Professor at Tokyo Medical University, Japan

2015-date Natalie C. Fredette, PhD

2014-2015 Nikolett M. Biel, PhD currently Staff Scientist, Otsuka Maryland Research Lab

2013-2014 Chae Ho Lim, PhD currently Postdoc at New York University

2010-2012 Aline Bonilla, PhD currently Senior Andrologist Cell Biologist, Minitube of America, WI

2010-2011 Ken-ichi Shinohara, PhD currently Research Scientist, Chiba University, Tokyo, Japan

2005-2007 Brad Willenberg, PhD currently Assistant Scientist, Internal Medicine, UCF

2005-2005 Young Dong Park, MD/PhD currently Staff Pediatric Oncologist, Osaka Medical Center

2000-2003 Yuka Nakano, MD/PhD currently Staff Psychiatrist, Osaka 2nd Police Hospital

2000-2003 Masahiro Oka, PhD currently Assistant Professor, Osaka University

2000-2003 Takashi Hamazaki, MD/PhD currently Professor, Osaka City University

2000-2003 Masanori Hoki, MD/PhD currently Professor, Osaka Shoin Women’s University

1998-1999 Tetsuo Minamino, MD/PhD currently Professor, Kagawa Medical University

1997-1999 Yasuhiko Iiboshi, MD/PhD currently Director, Surgery, Rinku General Medical Center

1995-1997 Hideki Kawasome, PhD currently Director, 3rd Institute of New Drug Discovery, Otsuka Pharm.

1994-1996 Hirotaka Sugiyama, MD/PhD currently Private Practice

Graduate Students Education:

PhD Thesis Mentor (GMS 7980, 7979)

2012-2016 Joonseok Cho, PhD currently Postdoc at Stanford University (B. Feldman)

2009-2013 Milena Leseva, PhD currently Postdoc at Harvard University (K. Michel)

2008-2013 Chae Ho Lim, PhD currently Postdoc at New York University (M. Ito)

2006-2011 Katherine Hankowski, PhD currently Assistant Scientist at Center for Cellular Reprogramming

2005-2008 Jeff Brower, PhD currently Resident in Radiation Oncology at University of Wisconsin

2004-2007 Sarah Kehoe, PhD currently Genomics Service Manager, Beckman Coulter

2003-2007 Michael Rutenberg, MD/PhD currently Assistant Professor in Radiation Oncology at UF Jacksonville

2003-2006 Amar Singh, PhD currently Assistant Scientist at University of Georgia.

2002-2005 Nemanja Rodic, MD, PhD currently Assistant Professor at University of Florida

2001-2002 Diana Mastalerz, MD currently Anesthesiologist at Lake Cumberland Reg Hp, Kentucky

MS Thesis Mentor (GMS 6905)

2004-2005 Kirk Giesbrandt, MS currently Resident in Radiology in Mayo Clinic, Jacksonville

2003-2005 Amy Meacham, MS currently Sr. Biol. Scientist at U Florida

1995-1997 Philip Papst, MS currently Senior Research Associate, Myogen, Inc

IDP 1st Year Rotation Mentor (GMS 6090)

2016-2017 Leanne Dumeny (Genetics & Genomics), Kevin Yu, Shu Guo

2015-2016 Bayli DiVita, Leanne Dumeny (MD/PhD), Kyle Dyson (summer rotations)

2014-2015 Leah Dannenberg

2013-2014 Ruan Oliveira, Chris Reid

2011-2012 Phil Doerfler, Janneth Oleas, Joon-Seok Cho, Lisa Lawson, Lizzi Butterworth

2010-2011 Leylah Drusbosky, Yun-Jong Park, Daniil Shabashvili


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2009-2010 Thu Le Trinh, Hyun Min Jung

2008-2009 Nikolett Molnar, Milena Leseva

2007-2008 Jen Maier, Deniz Ucar, Chae Ho Lim, Reddy Ranjith Sama

2006-2007 Chul Han

2005-2006 Jonathan Verrier, Katherine Hankowski, Dana Pintilie, Kyung Suk Choi

2004-2005 Matt Murawski, Jeff Brower

2003-2004 Jason O’Rourke, Kyung Hee Chang, Arne Heggestad, Sarah Kehoe, Shangli Lian

2002-2003 Amar Singh, Firas Kobeissy, Bei Wang, Youngme Jung, Kwon-Ho Hong

2001-2002 Barry Flanary, Rafal Witek, Nemanja Rodic

2000-2001 Diana Mastalerz, Hui-Jia Dong

Thesis Advisory Committee (GMS 7980, 7979)

2016-2017 Filipa Botelho Moniz PhD Candidate IDP Immunology & Microbiology, UF (Brusko)

2015-2017 Leah Dannenberg MS IDP Genetics, UF (Seaver)

2015-2017 Gavin Golas PhD IDP Immunology & Microbiology, UF (S. Wallet)

2015-2017 Karessa White PhD Speech, Language & Hearing Sciences, UF (Someya)

2015-date Lucas Armitage PhD Candidate IDP Immunology & Microbiology, UF (Wallet)

2014-2018 Ruan Oliveira PhD IDP Genetics, UF (Swanson)

2014-date Luiz Bolfer PhD Candidate Veterinary Medicine, UF (Estrada)

2014-2017 Nihal El Rouby PhD College of Pharmacy, UF (Johnson)

2013-2014 Adam Frock MS IDP Molecular Cell Biology, UF (Petersen)

2013-2015 David Sullivan PhD Biomedical Engineering, UF (McFetridge/Petersen)

2013-2017 Jared Taylor PhD IDP Immunology & Microbiology, UF (Wallet)

2013-2014 Ivan Sosa MS Veterinary Medicine, UF (Estrada)

2012-2017 Colleen Jeffrey PhD IDP Physiology & Pharmacology, UF (Raizada)

2012-2016 Lisa Lawson PhD IDP Genetics, UF (Harfe)

2011-2014 Yun-Jong Park PhD IDP Immunology & Microbiology, UF (Cha)

2010-2013 Mongjen Chen PhD College of Pharmacy, UF (Song)

2010-2014 Anna Denicol PhD Animal Sciences, UF (Hansen)

2010-2011 Yuan Lu MS Medical Sciences Program, UF (Srivastava)

2010-2016 Michael Lewis PhD IDP Genetics, UF (Resnick)

2010-2014 Yiming Yin PhD IDP Immunology & Microbiology, UF (Morel)

2009-2011 Tegan Lavoie MS Medical Sciences Program, UF (Peck)

2009-2012 Wendy Carcamo PhD IDP Molecular Cell Biology, UF (Chan)

2009-2011 Sonisha Warren PhD IDP Physiology & Pharmacology, UF (Kasahara)

2009-2010 Rushi Patel PhD IDP Molecular Cell Biology, UF (Chan)

2008-2013 Yong Hwan Kim PhD IDP Molecular Cell Biology, UF (Oh)

2008-2012 Jen Maier PhD IDP Genetics, UF (Harfe)

2008-2012 Candace Bichsel PhD IDP Genetics, UF (Jin)

2008-2012 Can Zhang PhD IDP Genetics, UF (Zhou)

2008-2012 Will Donelan PhD IDP Molecular Cell Biology, UF (Yang)

2008-2011 Chul Han PhD IDP Physiology & Pharmacology, UF (Oh)

2007-2012 Bing Yao PhD IDP Molecular Cell Biology, UF (Robertson/Chan)

2007-2012 Star Okada PhD IDP Genetics, UF (Chang)

2007-2008 Eun-Ji Lee MS Medical Sciences Program, UF (Oh)

2006-2010 Qien Yang PhD Animal Sciences, UF (Ealy)

2006-2011 Ekta Patel PhD IDP Genetics, UF (Chang)

2006-2011 Kyung-Suk Choi PhD IDP Genetics, UF (Harfe)

2006-2009 Nicole Steiger PhD IDP Molecular Cell Biology, UF (Petersen)

2006-2010 Meryem Cakiroglu PhD IDP Neuroscience, UF (Laywell)

2006-2009 Dana Pintilie PhD IDP Molecular Cell Biology, UF (Petersen)

2006-2007 Alicia Brown MS Medical Sciences Program, UF (Petersen)

2006-2010 Emily Smith PhD IDP Genetics, UF (Resnick)

2005-2013 Matthew Williams PhD Biomedical Engineering, UF (Batich)

2005-2009 Suhasni Gopalakrishnan PhD IDP Biochemistry, UF (Robertson)

2005-2009 Houda Darwiche PhD IDP Molecular Cell Biology, UF (Petersen)


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2005-2009 Susan Ellor PhD IDP Molecular Cell Biology, UF (Petersen)

2004-2008 Shangli Lian PhD IDP Molecular Cell Biology, UF (Chan)

2004-2008 Amy K. Chen PhD IDP Neuroscience, UF (Steindler)

2004-2009 Amanda DuBose PhD IDP Genetics, UF (Resnick)

2004-2007 Jennifer LaPlante MD/PhD UF (Petersen)

2003-2007 Kwon-Ho Hong PhD IDP Physiology & Pharmacology, UF (Oh)

2003-2006 Noah Walton PhD IDP Neuroscience, UF (Steindler)

2003-2005 Jason Batler PhD IDP Molecular Cell Biology, UF (Scott)

2002-2005 Steve Guthrie PhD IDP Molecular Cell Biology, UF (Scott)

2002-2006 Jeong Hoon Joo PhD IDP Molecular Cell Biology, UF (Sugrue)

2002-2006 Sean Kearns PhD IDP Molecular Cell Biology, UF (Steindler)

2002-2005 Rafal Witek PhD IDP Molecular Cell Biology, UF (Petersen)

2002-2005 Jie Deng PhD IDP Molecular Cell Biology, UF (Petersen)

2001-2005 Liya Pi PhD IDP Molecular Cell Biology, UF (Petersen)

2001-2006 Donghang Zheng PhD IDP Molecular Cell Biology logy, UF (Petersen)

2001-2005 Roman Alpatov PhD IDP Molecular Cell Biology logy, UF (Sugrue)

2001-2005 Chris Bray MD/PhD UF (Scott)

2000-2002 Frances R. Bahjat PhD IDP Immunology & Microbiology, UF (Moldower)

Undergraduate Students Education:

Research Mentor (BMS 4905)

2016-date Eliyah Malik

2015-2017 Greg Schwab

2014-2017 Di Xia Currently at UCSF

2014-2015 Bayli DiVita Currently in PhD program (IDP) at U Florida

2013-2015 Anastasiya Yakovenko Currently in MD program at U Florida

2013-2014 Alicia Lew Currently in MD program at U South Florida

2012-2012 Jennifer Thompson

2012-2014 Crysta Iv Currently in MD program at U Florida

2011-2013 Michala Lee Currently in MD program at Florida International University

2010-2012 You-Jin Jang

2010-2011 Alice Chow

2009-2011 Jessica Gilbert Currently in PhD program (Horticultural Sciences) at U Florida

2008-2012 Wai-Yee Leung PA at Nova Southeastern University, Neonate Clinics at Woodhull Med Ctr

2008-2012 Paola Esparragoza Currently in MD program at Temple University

2007-2010 Amy Rosenbluth MD at Jefferson University, Resident in General Surgery

2007-2009 Rebecca Kirschner MD at Virginia Tech Carilion School of Medicine

2006-2008 Joshua Rogozinski MD at U South Florida, Resident in Orthopedic Surgery

2006-2007 Ben Rogozinski MD at U Florida, Resident in Orthopedic Surgery

2005-2006 Stacey Stevens MD at UF, Resident in OB/GYN Naval Medical Center San Diego’s Balboa Hp

2005-2006 Shelley Stevens PharmD at UF

2005-2006 Laura Templeton

2005-2006 William Vinh Ngo DO program at Kansas City U

2005-2006 Isaac Boss PhD at UFCOM (IDP), Postdoctoral Fellow at Weill Cornell

2003-2004 Marina Scotti Currently PhD program (IDP) at U Florida

2003-2004 Kirk J Giesbrandt MD at U Miami, Resident in Radiology in Mayo Clinic, Jacksonville

2002-2005 Jamie Graddy MD at U Miami, Resident in Radiology in Mayo Clinic, Jacksonville

2002-2003 Peter Piacenti Founder & President, Give Hope Foundation

2001-2002 Ken-ichi Tagoku

2001 Thomas Russell PhD at UC Berkley

Foreign Medical Student Research Mentor

2018 Yui Miyagi, Mikoto Fujihara, Rina Takahashi (Tokyo Medical University, Japan)

2017 Mai Kasai, Kanami Iwama, Tamaki Nakamura, Monami Hayashi, Ko-ichi Dai, Ryotaro Sekimoto (Tokyo

Medical University, Japan), Airi Yokoyama (Hiroshima University, Japan)


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2016 Kohki Ota, Kousuke Nakazawa, Rei Abe, Shota Fukaura, Akiko Kitano (Tokyo Medical University),

Kyoko Matsui (Hiroshima Universiry)

2015 Momo Uchida, Masato Imai, Keiki Oikawa (Tokyo Medical University)

2014 Satoko Tahata (Tohoku University, Japan)

2012 Ryosuke Nakatsubo (Tokyo Medical University)

2012 Ryo Iwase (Tohoku University)

2011 Wakiko Hiranuma (Tohoku University)

2007 Hiroki Kato (Tohoku University)

High School Students Education:

Research Mentor

2005-2006 Raheen Bush

2003-2004 Elizabeth Cook Undergraduate at MIT

Science Fair Judge

2001-2008 Oak Hall High School

Awards:

2017 Term Professorship Award, University of Florida

2014 Doctoral Mentoring Award, University of Florida College of Medicine

2012 Technology Innovator Award, University of Florida

2010-2012 Education Incentive Award, University of Florida

2008-2012 Exemplary Teacher Award, University of Florida College of Medicine

2001 Top 10 Basic Science Teaching Faculty, University of Florida College of Medicine

1996 NIH First Award

Research Grants, Contracts, and Special Grants:

Active:

National Institutes of Health, R24 GM119977-01 (Terada) 20%

“A stem cell tactic to promote personalized medicine"

Principal Investigator, 7/1/16 - 6/30/19

National Institutes of Health, R01 HL064024 (Oh) 10%

“Role of Macrophages in HHT Pathogenesis and Therapy"

Co-Investigator, 7/6/15 - 4/30/19

National Institutes of Health, UC4 DK104194 (Mathews) 10%

“Genetic Regulation of Human Beta Cell Destruction"


National Institutes of Health, R03 HD087528-A1 (Cooke) 4.2%

“Membrane estrogen receptor 1 mediation of epigenetic effects of estrogen"


Department of Defense, RP161205 (Oh) 5%

"Pathogenesis of vascular malformations in hereditary hemorrhagic telangiectasia:

From disease mechanism to new therapies"


American Heart Association, Grant-in-Aid 16GRNT30980002 (Terada) 10%

"A stem cell tactic to promote personalized medicine in hypertension"

Principal Investigator, 7/1/16-6/30/18

American Heart Association, Scientist Development Grant 17SDG33410467 (Pacak) 1%


10

"Mechanisms of cardiac and skeletal muscle dysfunction in Barth syndrome"


Pending:

DoD/ARMI, (Angelini) 10%

“Advanced liver 3-D tissue models for drug development applications to support toxicology, drug metabolism, target ID &

pharmacology"

Co-Investigator, 7/1/18 - 6/30/20 (Stage 1, 1st year approved, not officially activated yet)

National Institutes of Health, R01 GM127898-A1 (Jin) 20%

“High efficiency genome editing tools for pluripotent stem cells"

Co-Principal Investigator, 9/1/18 - 8/31/22 (The original submission score: 24 percentile)

National Institutes of Health, R01 (Maden) 12.5%

“The causes of skin scarring and its resolution"

Co-Principal Investigator, 9/1/18 - 8/31/22

National Institutes of Health, R01 (Yang) 10%

“Functional Elements of the Prader-Willi Syndrome Imprinting Center"


National Institutes of Health, R01 (Wendler) 5%

“Influences of prenatal e-cigarette exposure on cardiovascular development and cardiac function in adult offspring"


Past:

University of Florida, Research Opportunity Fund (Byrne)

"Gene Therapy Correction of Frataxin Deficiency in Friedreich’s Ataxia"

Co-Investigator, 5/1/15-4/30/17

Clinical and Translational Science Institute (CTSI) (Terada)

“Center for Cellular Reprogramming”

Center Director, 4/1/14-3/30/17

Otsuka Pharmaceutical Inc. (Terada)

“ANT2 and Cancer"


National Institutes of Health, U01 GM074492 (Johnson)

“Pharmacogenomic Evaluation of Antihypertensive Responses"

Pilot Project Leader, 10/1/13-7/31/16

Thermo/Life Technologies (Terada)

“Generation of cardiomyocytes from disease-associated iPSC lines”


ReproCell (Terada)

“A novel protein delivery machinery for directed iPS cell differentiation”


Clinical and Translational Science Institute (CTSI) Pilot Project Award (Biel)

“The use of patient derived iPSC to study the PKC-α gene in hypertension”


University of Florida, Research Opportunity Fund (Petersen)

"Developing a functional bio-artificial liver device utilizing a decellularized matrix as a platform"


National Institutes of Food and Agriculture/USDA, 2011-67015-30688 (Hansen)

“Developmental programming during preimplantation programming"



11

National Institutes of Health, U01 HD060474 (Terada)

“Developing Male Contraceptives by Targeting ANT4"


Florida Department of Health, James and Ester King Research Grant 3KB04 (Terada)

"T3SS-Mediated Cardiomyocyte Engineering"


Sanford Burnham Research Institute (Terada)

“Inherited Orphan Muscle Diseases”

Consultant, 3/1/14-10/31/14

Department of Pathology, Experimental and Clinical Collaborative Award (ECCA) (Terada, Liu)

"Generation of iPSCs from Primary Pancreatic Cancer to Recapitulate Early Stages of the Disease"


Clinical and Translational Science Institute (CTSI) Novel Technologies Award (Jin)

“A Novel Protein Delivery Technology for Cellular Reprogramming”


Clinical and Translational Science Institute (CTSI) Novel Technologies Award (Terada)

“Generation of Disease-Affected Cell Types from Patient iPS Cells for Clinical Translational Research”


National Institutes of Health, RC1 GM091238-01 (Terada/Jin/Hamazaki)

“iPSC generation using protein injection and site-selective HDAC inhibition"

Contact Principal Investigator, 9/30/09-8/31/12

University of Florida Faculty Enhancement Opportunity (FEO) Award (Terada)


National Institutes of Health, U01 HD060474-02S1 (Terada)

"Developing Male Contraceptives by Targeting ANT4"


University of Florida IFAS Research Innovation Grant (Hansen)

“Development of Pluripotent Stem Cells in Cattle”


Otsuka Pharmaceutical Inc. (Terada)

"Small compounds inhibiting ADP/ATP exchange through ANT2"


University of Florida, Research Opportunity Fund (Jin)

"Bacteria Mediated Delivery of Reprogramming Factors"


Wyeth Pharmaceuticals Protocol #0648G1-4469 (Terada)

"Inhibition of PI3K/Akt/mTOR Pathway by Rapamycin and Its Effect on Liver Fibrosis"


National Institutes of Health, R01 DK065096 (Petersen)

"Stem Cells in Liver Regeneration: Fusion or Plasticity"


National Institutes of Health, P01 GM085354 (Dalton)

"Understanding mechanisms of hESC self-renewal and cell fate commitment"

Pilot Project "Facilitating cardiac differentiation of hESCs by -catenin modulation"

Pilot Project PI, 12/1/08-7/31/09

McKnight Brain Institute (Terada)

"MicroRNAs in Adult Organ Homeostasis, Regeneration and Aging"



12

UF center for the Cardiovascular Cell Therapy Research Network (Terada)

"Nkx2.5-Positive Cardiac Progenitors in Spleen and Bone Marrow"


Florida Department of Health, Bankhead-Coley Biomedical Research Grant 06BCBG1-22 (Terada)

"Myelodysplastic syndrome, Dnmt3 and Azacytidine"


McKnight Brain Institute (Terada)

"Epigenetic Modifications of Pluripotent Stem Cell-Specific Genes in Human Cancer"


National Institutes of Health, R01 DK059699 (Terada)

"Generation of Hepatocyte Precursors from Mouse Embryonic Stem Cells"


University of Florida Shands Cancer Center, NCI Program Project Development Award (Terada)

"Myelodysplastic Syndrome, DNA Methylation and Azacytidine"


American Heart Association, Grant-in-Aid Florida/Puerto Rico Affiliate, 0455398B (Terada)

"Temporal and lineage-specific modulation of beta-catenin activity to facilitate cardiac differentiation of mouse ES cells"


National Institutes of Health, R13 DK065938 (Terada)

"Signal Transduction Determining the Fate of Stem Cells"

2003 Summer Meeting, The American Society for Cell Biology

Principal Investigator, Conference Chair, 9/20/03-7/31/04

University of Florida, Research Opportunity Fund (Terada)

"Hunting Genes for Somatic Cell Reprogramming"


National Institutes of Health, R21 RR017001 (Terada)

"Generation of Pluripotent Stem Cell Using ES Cell Cytoplast"


National Institutes of Health, R29 CA064685 (Terada)

"p70/85 S6 kinase and selective translational regulation"


VistaGen, Inc. (Terada)

"Development of a Novel Screening System for Expanding Functional Hepatocytes in Differentiating Embryonic Stem

Cells"


Howard Hughes Medical Institute, Biomedical Research Support Program for Medical Schools, UFCM (Terada)

"Role of intracellular signaling molecules in cardiac hypertrophy: Study using embryonic stem cell-derived cardiac

myocytes"


American Heart Association, Grant-in-Aid in Desert/Mountain Affiliate 9951086Z (Terada)

"Cardiomyocyte derived from gene-targeted embryonic stem cells: role of p70 S6 kinase in cardiac hypertrophy"


Cancer League of Colorado (Terada)

"Amino acid dependent control of the mTOR/p70s6k pathway"


Chugai Pharmaceutical Inc. (Terada)

"Effects of nicorandil on vascular remodeling and cardiac hypertrophy through activation of p70 S6 kinase in rabbit with

inhibition of NO synthesis"



13

Otsuka America Pharmaceutical Inc. (Gelfand/Terada)

"Involvement of adenosine in vesnarinone's biological action, Mechanism of adenosine- and/or allergy-related signal

transduction"

Co-Principal Investigator, 10/1/95-9/30/99

Otsuka Pharmaceutical Co. (Gelfand/Terada)

"Nucleoside and nucleobase transport inhibitors"


Otsuka Pharmaceutical Co. (Gelfand/Terada)

"Inhibition of Cell Cycle Progression by Arkin Z"


American Cancer Society/University of Colorado Cancer Center, IRG 5-33 (Terada)

"Differential effects of rapamycin on p70 S6 kinase phosphorylation and cell proliferation"


Publications:

Refereed Original Articles: (Total Citation: 11633, h-index: 48, i-10 index: 112)

No. Google

Scholar

Citations

Authors, Title, Journal, Volume, Pages, Year, PMCID

128.

Bertholet AM, Fedorenko A, Cho J, Terada N, Wallace DC, Kirichok Y:

Proton transport is an integral function of the mitochondrial ADP/ATP carrier.

Nature In submission

127.

Wang Y, Hao L, Santostefano K, Thapa A, Li H, Guo X, Terada N, Ashizawa T, Valenzuela F, Xia G:

Therapeutic genome editing for myotonic dystrophy type 1 using CRISPR/Cas9.

Mol. Ther. In submission

126.

Takeda K, Ning F, Domenico J, Okamoto M, Ashino S, Kim S-H, Jeong YY, Shiraishi Y, Terada N,

Sutherland ER, Gelfand EW:

Mesenchymal stem cell expression of p70S6 Kinase-1 is essential to lung tissue repair.

Stem Cells Transl. Med. In press, 2018

125.

0

White K, Kim MJ, Han C, Park HJ, Ding D, Boyd K, Walker L, Linser P, Meneses Z, Slade C, Hirst J,

Santostefano K, Terada N, Miyakawa T, Tanokura M, Salvi R, Someya S:

Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice.

Sci Rep. 8:5039, Mar, 2018 [PMCID: PMC5864918]

124.

0

Taylor JP, Cash MN, Nakanishi M, Santostefano KE, Terada N, Wallet MA:

The interferon-induced protein USP18 is a negative regulator of type 1 IFN and is required for HIV-1

infection in macrophages.

J Leukoc. Biol. In press, 2018 doi: 10.1002/JLB.3MIA0917-352R [PMID 29437254]

123.

0

Jin Y, Liu Y, Li Z, Simmons C, Santostefano KE, Shi J, Zhang X, Wu D, Cheng Z, Wu W, Terada N, Jin S,

Bai F:

Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacterial injection of

transcription factor cocktail.

PloS One. 13:e0194895, Mar, 2018 [PMCID: PMC5868831]

122.

1

Ferreira RB, Wang M, Law ME, Davis BJ, Bartley AN, Higgins PJ, Kilberg MS, Santostefano KE, Terada N,

Heldermon CD, Castellano RK, Law BK:

Disulfide bond disrupting agents activate the unfolded protein response in EGFR- and HER2-positive

breast tumor cells.

Oncotarget 8:28971-9, Apr, 2017 [PMCID: PMC5438706]

121.

1

Cho J, Zhang Y, Park SY, Joseph AM, Han C, Park HY, Kalavalapalli S, Chun SK, Morgan D, Kim JS,

Someya S, Mathews CE, Lee YJ, Wohlgemuth SE, Sunny NE, Lee HY, Choi CS, Shiratsuchi T, Oh SP, Terada

N:

Mitochondrial ATP transporter depletion protects mice from liver steatosis and insulin resistance.

Nat. Commun. 8:14477, Feb, 2017 [PMID 28205519]


14

120.

24

Deng C, Li Y, Zhou L, Cho J, Patel B, Terada N, Li Y, Bungert J, Qiu Y, Huang S:

HoxBlinc RNA recruits Set1/MLL complexes to activate Hox gene expression patterns and mesoderm

lineage development.

Cell Rep. 14:103-14, Jan, 2016 [PMCID:PMC4706800]

119.

1

Zhang Y, Tian D, Matsuyama H, Hamazaki T, Shiratsuchi T, Terada N, Hook D, Walters MA, Georg GI,

Hawkinson JE:

Human adenine nucleotide translocase (ANT) modulators identified by high-throughput screening of

transgenic yeast.

J. Biomol. Screen. 21:381-90, Apr, 2016 [PMID 26746582]

118.

8

Willenberg BJ, Oca-Cossio J, Cai Y, Brown AR, Clapp WL, Abrahamson DR, Terada N, Ellison GW,

Mathews CE, Batich CD, Ross EA:

Repurposed biological scaffolds: Kidney to pancreas

Organogenesis 11:47-57, Apr, 2015 [PMCID:PMC4594556]

117.

8

Gao Y, Guo X, Santostefano KE, Wang Y. Reid T, Zeng D, Terada N, Ashizawa T, Xia G:

Genome therapy of myotonic dystrophy type 1 iPS cells for development of autologous stem cell therapy.

Mol. Ther. 24:1378-87, Aug, 2016 [PMID 27203440]

116.

Hattori T, Hamazaki T, Kudo S, Santostefano KE, Terada N, Shintaku H:

Patient-specific induced pluripotent stem cells to model MELAS/Leigh overlap syndrome with

mitochondrial DNA T10191C mutation. PLoS One In revision

115.

10

Biel NM*, Santostefano KE, DiVita BB, El Rouby N, Carrasquillas S, Simmons C, Nakanishi M, Cooper-

DeHoff RM, Johnson JA, Terada N*:

Vascular smooth muscle cells from hypertensive patient-derived induced pluripotent stem cells to advance

hypertension pharmacogenomics

Stem Cells Transl. Med. 4:1380-90, Dec, 2015 (*co-corresponding authors) [PMCID:PMC4675511]

114.

16

Bai F, Lim CH, Jia J, Santostefano KE, Simmons C, Kasahara H, Terada N*, Jin S*:

Directed differentiation of embryonic stem cells into cardiomyocytes by bacterial injection of defined

transcriptional factors

Sci. Rep. 5:15014, Oct, 2015 (*co-corresponding authors) [PMCID:PMC4598736]

113.

7

Jia J, Bai F, Santostefano KE, Wu D, Wu W*, Terada N*, Jin S*:

Efficient gene editing in pluripotent stem cells by bacterial injection of TALEN proteins

Stem Cells Transl. Med. 4:913-26, Aug, 2015 (*co-corresponding authors) [PMCID:PMC4511150]

112.

12

Cho J, Seo J, Lim CH, Yang L, Shiratsuchi T, Lee MH, Chowdhury RR, Kasahara H, Kim JS, Oh SP, Lee YJ,

Terada N:

Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis

Cell Death. Differ. 22:1437-50, Sep, 2015 [PMCID:PMC4532771]

111.

26

Xia G, Gao Y, Jin S, Subramony SH, Terada N, Ranum LPW, Swanson MS, Ashizawa T:

Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent

stem cell-derived neural stem cells.

Stem Cells 33:1829-38, Jun, 2015 [PMCID:PMC4441571]

110.

5

Lim CH, Brower JV, Resnick JL, Oh SP, Terada N:

Ant4 is expressed within embryonic ovaries and dispensable during oogenesis

Reprod. Sci. 22:250-7, Feb, 2015 [PMCID:PMC4287603]

109.

17

Neeld D, Jin Y, Bichsel C, Jia J, Guo J, Bai F, Wu W, Ha UH, Terada N, Jin S:

Pseudomonas aeruginosa injects NDK into host cells through type III secretion system

Microbiol. 160:1417-26, Jul, 2014 [PMCID:PMC4076871]

108.

25

Jia J, Jin Y, Ting B, Wu D, Yang LJ, Terada N, Wu W, Jin S:

Bacterial delivery of TALEN proteins for human genome editing

PLoS One 9:e91457, Mar, 2014 [PMCID: PMC3950253]

107.

8

Chen MJ, Lu Y, Hamazaki T, Tsai HY, Erger K, Conlon T, Elshikha AS, Li H, Srivastava A, Yao C, Brantly M,

Chiodo V, Hauswirth W, Terada N, Song S:

Reprogramming adipose tissue derived mesenchymal stem cells into pluripotent stem cells by a mutant

adeno-associated viral vector

Hum. Gene Ther. Methods 25:72-82, Feb, 2014 [PMCID: PMC3904654]

http://www.ncbi.nlm.nih.gov/pubmed?term=Neeld%20D%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Jin%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Bichsel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Jia%20J%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Guo%20J%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Bai%20F%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Wu%20W%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Ha%20UH%5BAuthor%5D&cauthor=true&cauthor_uid=24699069

http://www.ncbi.nlm.nih.gov/pubmed?term=Terada%20N%5BAuthor%5D&cauthor=true&cauthor_uid=24699069


15

106.

33

Xia G, Santostefano K, Hamazaki T, Liu J, Subramony SH, Terada N, Ashizawa T:

Generation of human induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro

J. Mol. Neurosci. 51:237-48, Oct, 2013 [PMCID: PMC3608734]

105.

5

Leung WY, Hamazaki T, Ostrov DA, Terada N:

Identification of adenine nucleotide translocase 4 inhibitors by molecular docking

J. Mol. Graph. Model. 45:173-179, Sep, 2013 [PMCID: PMC3821932]

104.

7

Shan J, Hamazaki T, Tang T, Terada N, Kilberg MS:

Activation of the amino acid response modulates lineage specification during differentiation of murine

embryonic stem cells.

Am. J. Physiol. 305:E325-35, Aug, 2013 [PMID: 23736538]

103.

7

Leseva M, Santostefano KE, Rosenbluth A, Hamazaki T, Terada N:

E2f6-mediated repression of the meiotic Stag3 and Smc1β genes during early embryonic development

requires Ezh2 and not the de novo methyltransferase Dnmt3b

Epigenetics 8:873-84, Aug, 2013 [PMCID: PMC3883790]

102.

7

Wang Q, Wang H, Sun Y, Li S-W, Donelan W, Chang L-J, Jin S, Terada N, Cheng H, Reeves W, Yang L-J:

The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to

pancreatic beta cell differentiation

J. Cell. Sci. 126:3638-48, Aug, 2013 [PMCID: PMC3774026]

101.

25

Xia G, Santostefano K, Goodwin M, Liu J, Subramony SH, Swanson MS, Terada N*, Ashizawa T*:

Generation of Neural Cells from DM1 Induced Pluripotent Stem Cells As Cellular Model for the Study of

Central Nervous System Neuropathogenesis

Cell. Reprogram. 15:166-77, Apr, 2013. [PMCID: PMC3616452] (*co-corresponding authors)

100.

34

Bichsel C, Neeld D, Hamazaki T, Chang LJ, Yang LJ, Terada N, Jin S:

Direct reprogramming of fibroblasts to myocytes via bacterial injection of MyoD protein

Cell. Reprogram. 15: 117-25, Feb, 2013 [PMCID: PMC3616421]

99.

12

Della Rocca DG, Willenberg BJ, Ferreira LF, Wate PS, Petersen JW, Handberg EM, Zheng T, Steindler DA,

Terada N, Batich CD, Byrne BJ, Pepine CJ:

A degradable, bioactive, gelatinized alginate hydrogel to improve stem cell/growth factor delivery and

facilitate healing after myocardial infarction.

Med. Hypotheses 79:673-7, Nov, 2012 [PMCID: PMC3725557]

98.

16

Santostefano KE, Hamazaki T, Pardo CE, Kladde MP, Terada N:

Fibroblast Growth Factor Receptor 2 homodimerization rapidly reduces transcription of the pluripotency

gene Nanog without dissociation of activating transcription factors.

J. Biol. Chem. 287:30507-17, Aug, 2012 [PMCID: PMC3436299]

97.

14

Ozawa M, Sakatani M, Hankowski KE, Terada N, Dobbs K, Hansen PJ:

Importance of culture conditions during the morula-to-blastocyst period on capacity of inner cell mass cells

of bovine blastocysts for establishment of self-renewing pluripotent cells.

Theriogenology 78:1243-51, Aug, 2012 [PMID: 22898023]

96.

77

Ross EA, Abrahamson DR, St. John PL, Clapp WL, Williams MJ, Terada N, Hamazaki T, Ellison GW, Batich

CD:

Mouse stem cells seeded into decellulalized rat kidney scaffolds endothelialize and remodel basement

membranes

Organogenesis 8:49-55, Apr, 2012 [PMCID: PMC3429512]

95.

71

Carcamo WC, Satoh M, Kasahara H, Terada N, Hamazaki T, Chan JYF, Yao B, Tamayo S, Covini G, von

Mühlen CA, Chan EKL:

Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in

mammalian cells

PLoS One 6, e29690, Dec, 2011 [PMCID: PMC3248424]


16

94.

47

Pandian GN, Shinohara K, Ohtsuki A, Nakano Y, Masafumi M, Bando T, Nagase H, Yamada Y, Watanabe A,

Terada N, Sato S, Morinaga H, Sugiyama H:

Synthetic small molecules for epigenetic activation of pluripotent genes in mouse embryonic fibroblasts

Chembiochem. 12:2822-8, Dec, 2011 [PMID:22038863]

93.

10

Lim CH, Hamazaki T, Braun EL, Wade J, Terada N:

Evolutionary genomics implies a specific function of Ant4 in mammalian and anole lizard male germ cells.

PLoS One 6:e23122, Aug, 2011 [PMCID: PMC3155547]

92.

13

Hamazaki T, Leung WY, Cain BD, Ostrov DA, Thorsness PE, Terada N:

Functional expression of human adenine nucleotide translocase 4 in Saccharomyces cerevisiae

PLoS One 6:e19250, Apr, 2011 [PMCID: PMC3080916]

91.

6

Willenberg BJ, Zheng T, Meng FW, Meneses JC, Rossignol C, Batich CD, Terada N, Steindler DA, Weiss MD:

Gelatinized copper-capillary alginate gel functions as an injectable tissue scaffolding system for stem cell

transplants.

J. Biomat. Sci. Polym. Ed. 22:1621-37, Apr, 2011 [PMCID: PMC3753783]

90.

28

Bichsel C, Neeld DK, Hamazaki T, Chang LJ, Yang L, Terada N, Jin S:

Bacterial mediated delivery of nuclear protein into pluripotent and differentiated cells

PLoS One 6:e16465, Jan, 2011 [PMCID: PMC3029358]

89.

87

Ge Y, Wu AL, Warnes C, Liu J, Zhang C, Kawasome H, Terada N, Boppart M, Schoenherr CJ, Chen J:

mTOR regulates skeletal muscle regeneration through kinase-dependent and kinase-independent

mechanisms

Am. J. Physiol. 297:C1434-44, Dec, 2009 [PMCID: PMC2793064]

88.

276

Ross E, Williams M, Hamazaki T, Terada N, Clapp W, Adin C, Ellison G, Jorgensen M, Batich C:

Embryonic stem cells proliferate and differentiate when seeded into kidney scaffolds

J. Am. Soc. Nephrol. 20:2338-47, Nov, 2009 [PMCID: PMC2799178]

87.

64

Gopalakrishnan S, Van Emburgh BO, Shan J, Su Z, Fields CR, Vieweg J, Hamazaki T, Schwartz PH, Terada

N, Robertson KD:

A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA

methylation patterns and displays altered DNA binding

Mol. Cancer Res. 7:1622-34, Oct, 2009 [PMCID: PMC2783805]

86.

45

Brower JV, Lim CH, Jorgensen M, Oh SP, Terada N:

Adenine nucleotide translocase 4 deficiency leads to early meiotic arrest of murine male germ cells.

Reproduction 138:455-62, Sep, 2009 [PMCID: PMC3727218]

85.

14

Brower JV, Lim CH, Han C, Hankowski KE, Hamazaki T, Terada N:

Differential CpG island methylation of murine adenine nucleotide translocase genes

Biochim. Biophys. Acta 1789:198-203, Mar, 2009 [PMCID: PMC2671066]

84.

23

Kehoe SM, Oka M, Hankowski KE, Reichert N, Garcia S, McCarrey JR, Gaubatz S, Terada N:

A conserved E2F6-binding element in murine meiosis-specific gene promoters

Biol. Reprod. 79:921-30, Nov, 2008 [PMCID: PMC2715002]

83.

321

Singh AM, Hamazaki T, Hankowski KE, Terada N:

A heterogeneous expression pattern for Nanog in embryonic stem cells.

Stem Cells 25:2534-42, Oct, 2007

82.

67

Brower JV, Rodic N, Seki T, Jorgensen M, Fliess N, Yachnis AT, McCarrey JR, Oh SP, Terada N:

Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis

J. Biol. Chem. 282:29658-66, Oct, 2007

81.

48

Lian S, Fritzler, MJ, Katz J, Hamazaki T, Terada N, Satoh M, Chan EKL:

Small interfering RNA-mediated silencing induces target-dependent assembly of GW/P bodies.

Mol. Biol. Cell 18:3375-87, Sep, 2007 [PMCID: PMC1951753]


17

80.

50

Li F-Q, Singh AM, Mofunanya A, Love D, Terada N, Moon RT, Takemaru K-I:

Chibby promotes adipocyte differentiation through inhibition of -catenin signaling.

Mol. Cell. Biol. 27:4347-54, Jun, 2007 [PMCID: PMC1900052]

79.

80

Singh AM, Li, F-Q, Hamazaki T, Kasahara H, Takemaru K-I, Terada N:

Chibby, an antagonist of the Wnt/β-catenin pathway, facilitates cardiomyocyte differentiation of murine

embryonic stem cells.

Circulation 115:617-26, Feb, 2007 [PMCID: PMC2565513]

78.

34

Willenberg BJ, Hamazaki T, Meng FM, Terada N, Batich CD:

Self-assembled copper-capillary alginate gel scaffolds with oligochitosan support embryonic stem cell

growth

J. Biomed. Mater. Res. 79A:440-50, Nov, 2006

77.

139

Hamazaki T, Kehoe SM, Nakano T, Terada N:

The Grb2/Mek pathway represses Nanog in murine embryonic stem cells.

Mol. Cell. Biol. 26:7539-49, Oct, 2006 [PMCID: PMC1636849]

76.

60

Oka M, Rodic N, Graddy J, Chang L-J, Terada N:

CpG sites preferentially methylated by Dnmt3a

J. Biol. Chem. 281:9901-8, Apr, 2006

75.

77

Zhou H, Liu H, Porvasnik S, Terada N, Agarwal A, Chen Y, Visner GA:

Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary

hypertension

Lab. Invest. 86:62-71, Jan, 2006

74.

89

Rodic N, Oka M, Hamazaki T, Murawski MR, Jorgensen M, Maatouk DM, Resnick JL, Li E, Terada N:

DNA methylation is required for silencing of Ant4, an adenine nucleotide translocase selectively expressed

in mouse embryonic stem cells and germ cells.

Stem Cells 23:1314-23, Oct, 2005

73.

110

Oka M, Meacham AM, Hamazaki T, Rodic N, Chang L-J, Terada N:

De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-

deoxycytidine.

Oncogene 24:3091-9, Apr, 2005 (Covered Article)

72.

7

Nakano Y, Hirko AC, Smith AD, Oka M, Peris J, Dawson R, Terada N, Meyer EM:

Presynaptic dopaminergic properties of differentiated mouse embryonic stem cells

Neurochem. Int. 45:1067-73, Dec, 2004

71.

64

Zhu H, Shang X, Terada N, Liu C:

STAT3 induces anti-hepatitis C viral RNA activity in liver cells.

Biochem. Biophys. Res. Commun. 324:518-28, Nov, 2004

70.

128

Hamazaki T, Oka M, Yamanaka S, Terada N:

Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.

J. Cell Science 117:5681-6, Nov, 2004

69.

362

Chinzei R, Tanaka Y, Shimizu-Saito K, Hara Y, Kakinuma S, Watanabe M, Teramoto K, Arii S, Takase K, Sato

C, Terada N, Teraoka H:

Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional

hepatocytes.

Hepatology 36:22-9, Jul, 2002

68.

2489

Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, Nakano Y, Meyer EM, Morel L, Petersen BE, Scott

EW:

Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion.

Nature 416:542-5, Apr, 2002 (Covered Article)


18

67.

135

Oka M, Tagoku K, Russell T, Nakano Y, Hamazaki T, Meyer EM, Yokota T, Terada N:

CD9 is associated with leukemia inhibitory factor-mediated maintenance of embryonic stem cells.

Mol. Biol. Cell 13:1274-81, Apr, 2002 [PMCID: PMC102268]

66.

122

Minamino T, Yujiri T, Terada N, Taffet GE, Michael LH, Johnson GL, Schneider MD:

MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.

Proc. Natl. Acad. Sci. USA 99:3866-71, Mar, 2002

65.

99

Sanada S, Kitakaze M, Papst PJ, Asanuma H, Node K, Takashima S, Asakura M, Ogita H,Liao Y, Sakata Y,

Ogai A, Fukushima T, Yamada J, Shinozaki Y, Kuzuya T, Mori H, Terada N, Hori M:

Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors: the role of

protein kinase A and p38 mitogen-activated protein kinase.

Circulation 104:705-10, 2001

64.

537

Harada H, Andersen J, Mann M, Terada N, Korsmeyer SJ:

P70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

Proc. Natl. Acad. Sci. USA 98:9666-70, 2001

63.

702

Wang X, Li W, Williams M, Terada N, Alessi DR, Proud CG:

Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase

EMBO J. 20:4370-9, Aug, 2001

62.

530

Hamazaki T, Iiboshi Y, Oka M, Papst PJ, Meacham AM, Zon LI, Terada N:

Hepatic maturation in differentiating embryonic stem cells in vitro.

FEBS Letters 497:15-9, Mar, 2001

61.

131

Sanada S, Kitakaze M, Papst PJ, Hatanaka K, Asanuma H, Aki T, Shinozaki Y, Ogita H, Node K, Takashima S,

Asakura M, Yamada J, Fukushima T, Ogai A, Kuzuya T, Mori H, Terada N, Yoshida K, Hori M:

Role of phasic dynamism of P38 mitogen-activated protein kinase activation in ischemic preconditioning of

the canine heart.

Circulation Res. 2:175-80, 2001

60.

24

Minamino T, Kitakaze M, Papst PJ, Ueda Y, Sakata Y, Asanuma H, Ogai A, Kuzuya T, Terada N, Hori M:

Inhibition of nitric oxide synthesis induces coronary vascular remodeling and cardiac hypertrophy

associated with the activation of p70 S6 kinase in rats.

Cardiovasc Drugs Ther. 14:533-42, Oct, 2000

59.

7

Minamino T, Kitakaze M, Ueda Y, Asanuma H, Papst PJ, Kuzuya T, Terada N, Hori M:

Chronic treatment with FK506 increases p70 S6 kinase activity associated with reduced nitric oxide

synthase activity in rabbit hearts.

Cardiovasc Drugs Ther 14:329-36, Jun, 2000

58.

15

Sakata N, Hamelmann E, Siadak AW, Terada N, Gerwins P, Aruffo A, Johnson GL, Gelfand EW:

Differential regulation of CD40-mediated human B cell responses by antibodies directed against different

CD40 epitopes.

Cell Immunol. 201:109-23, 2000

57.

11

Sakata N, Kawasome H, Terada N, Johnson GL, Gelfand EW:

CD40 and adenosine A2 receptor agonist/cyclic AMP rescue B cell antigen receptor induced apoptosis via

independent pathways.

J. Allergy Clin. Immunol. 105:522-31, 2000

56.

154

Minamino T, Yujiri T, Papst PJ, Chan ED, Johnson GL, Terada N:

MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes.

Proc. Natl. Acad. Sci. USA 96:15127-32, Dec, 1999

55.

147

Lee-Fruman KK, Kuo CJ, Lippincott J, Terada N, Blenis J:

Characterization of S6K2, a novel kinase homologous to S6K1.

Oncogene 18:5108-14, 1999


19

54.

57

Iiboshi Y, Papst PJ, Hunger SP, Terada N:

L-asparaginase inhibits the rapamycin-targeted signaling pathway.

Biochem. Biophys. Res. Commun. 260:534-9, Jul, 1999

53.

22

Fujita M, Norris DA, Yagi H, Walsh P, Morell JG, Weston WL, Terada N, Bennion SD, Robinson W, Lemon

M, Maxwell IH, Yohn JJ:

Overexpression of mutant ras in human melanoma increases invasiveness, proliferation and anchorage-

independent growth in vitro and induces tumour formation and cachexia in vivo.

Melanoma Res. 9:279-91, 1999

52.

81

Schwab MS, Kim SH, Terada N, Edfjäll C, Kozma SC, Thomas G, Maller JL:

The p70s6k controls selective mRNA translation during oocyte maturation and early embryogenesis in

Xenopus laevis.

Mol. Cell. Biol. 19: 2485-94, Apr, 1999

51.

223

Iiboshi Y, Papst PJ, Kawasome H, Hosoi H, Abraham RT, Houghton PJ, Terada N:

Amino acid-dependent control of p70s6k: Involvement of tRNA aminoacylation in the regulation.

J. Biol. Chem. 274:1092-9, Jan, 1999

50.

33

Sakata N, Kawasome H, Terada N, Gerwins P, Johnson GL, Gelfand EW:

Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor

and CD40 in human B cells.

Eur. J. Immunol. 29:2999-3008, 1999

49.

118

Ishizuka T, Chayama K, Takeda K, Hamelmann E, Terada N, Keller GM, Johnson GL, Gelfand EW:

Mitogen-activated protein kinase activation through Fcε receptor I and stem cell factor receptor is

differentially regulated by phosphatidylinositol 3-kinase and calcineurin in mouse bone marrow-derived

mast cells.

J. Immunol. 162:2087-94, Feb, 1999

48.

58

Papst P, Sugiyama H, Nagasawa M, Lucas JJ, Maller JL, Terada N:

Cdc2-cyclin B phosphorylates p70 S6 kinase on Ser411 at mitosis.

J. Biol. Chem. 273:15077-84, Jun, 1998

47.

206

Kawasome H, Papst P, Webb S, Keller GM, Johnson GL, Gelfand EW, Terada N:

Targeted disruption of p70s6k defines its role in protein synthesis and rapamycin sensitivity.

Proc. Natl. Acad. Sci. USA 95:5033-8, Apr, 1998.

46.

60

Ishizuka T, Kawasome H, Terada N, Takeda K, Gerwins P, Keller GM, Johnson GL, Gelfand EW:

Stem cell factor augments FcεRI-mediated TNF-α production and stimulates MAP kinases via a different

pathway in MC/9 mast cells.

J. Immunol. 161:3624-30, Oct, 1998.

45.

45

Jeppson JD, Patel HR, Sakata N, Domenico J, Terada N, Gelfand EW:

Requirement for dual signals by anti-CD40 and IL-4 for the induction of nuclear factor-κB, IL-6, and IgE

in human B lymphocytes.

J. Immunol. 161:1738-42, 1998.

44.

13

Kitakaze M, Fong M, Yoshitake M, Minamino T, Node K, Okuyama Y, Terada N, Kambayashi T, Hori M:

Vesnarinone inhibits adenosine uptake in endothelial cells, smooth muscle cells and myocytes, and

mediates cytoprotection.

J. Mol. Cell. Cardiol. 29:3413-7, 1997.

43.

143

Ishizuka T, Terada N, Gerwins P, Hamelmann E, Oshiba A, Fanger GR, Johnson GL, Gelfand EW:

Mast cell tumor necrosis factor production is regulated by MEK kinases.

Proc. Natl. Acad. Sci. USA 94:6358-63, 1997.

42.

10

Sugiyama H, Papst P, Fujita M, Gelfand EW, Terada N:

Overexpression of wild type p70 S6 kinase interferes with cytokinesis.

Oncogene 15:443-52, Jul, 1997.


20

41.

53

Ishizuka T, Sakata N, Johnson GL, Gelfand EW, Terada N:

Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid

cells.

Biochem. Biophys. Res. Commun. 230:386-91, 1997.

40.

30

Sugiyama T, Papst P, Gelfand EW, Terada N:

p70 S6 kinase sensitivity to rapamycin is eliminated by amino acid substitution of Thr229.

J. Immunol. 157:656-60, Jul, 1996.

39.

10

Takase K, Kelleher CA, Terada N, Jones JF, Lucas JJ, Gelfand EW:

Dissociation of EBV genome replication and host cell proliferation in anti-IgG-stimulated Akata cells.

Clin. Immunol. Immunopathol. 81:168-74, Nov, 1996.

38.

4

Franklin RA, Sawami H, Terada N, Lucas JJ, Gelfand EW:

Activation of p42erk2 MAPK and p90rsk by IL-2 occurs independently of protein kinase C.

Clin. Immunol. Immunopathol. 80:116-22, Aug, 1996.

37.

11

Patel HR, Terada N, Gelfand EW:

Rapamycin-sensitive phosphorylation of ribosomal protein S17 by p70s6k.

Biochem. Biophys. Res. Commun. 227:507-12, Oct, 1996.

36.

73

Ishizuka T, Oshiba A, Sakata N, Terada N, Johnson GL, Gelfand EW:

Aggregation of the FcεRI on mast cells stimulates c-Jun amino terminal kinase activity. A response

inhibited by wortmannin.

J. Biol. Chem. 271:12762-6, 1996.

35.

191

Sakata N, Patel HR, Terada N, Johnson GL, Gelfand EW:

Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells.

J. Biol. Chem. 270:30823-8, Dec, 1995.

34.

78

Terada N, Takase K, Papst P, Nairn AC, Gelfand EW:

Rapamycin inhibits ribosomal protein synthesis and induces G1 prolongation in mitogen-activated T

lymphocytes.

J. Immunol. 155:3418-26, 1995.

33.

37

Franklin RA, Brodie C, Melamed I, Terada N, Lucas JJ, Gelfand EW:

Nerve growth factor induces activation of MAP-kinase and p90rsk in human B lymphocytes.

J. Immunol. 154:4965-72, 1995

32.

63

Lucas JJ, Szepesi A, Domenico J, Takase K, Tordai A, Terada N, Gelfand EW:

Effects of iron-depletion on cell cycle progression in normal human T lymphocytes: selective inhibition of

the appearance of the cyclin A-associated comonent of p33cdk2 kinase.

Blood 86:2268-80, 1995

31.

13

Modiano JF, Domenico J, Szepesi A, Terada N, Lucas JJ, Gelfand EW:

Symmetry of the activation of cyclin-dependent kinase in mitogen and growth factor-stimulated T

lymphocytes.

Ann. NY Acad. Sci. 766:134-48, 1995

30.

19

Kumakura T, Takase K, Terada N, Gelfand EW:

Vesnarinone inhibits nucleoside and nucleobase transport.

Life Sciences 57: PL75-81, 1995

29.

30

Lucas JJ, Szepesi A, Domenico J, Tordai A, Terada N, Gelfand EW:

Differential regulation of the synthesis and activity of the major cyclin-dependent kinases, p34cdc2, p33cdk2

and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes.

J. Cell. Physiol. 165:406-16, 1995

28.

25

Franklin RA, Tordai A, Mazer B, Terada N, Lucas JJ, Gelfand EW:

Platelet activating factor activates MAPK and increases in intracellular calcium via independent pathways

in B lymphocytes.

Biochem. Biophys. Res. Commun. 209:1111-8, 1995


21

27.

10

Takase K, Terada N, Lucas JJ, Gelfand EW:

Control of cell cycle entry and progression in mitogen-stimulated human B lymphocytes.

J. Cell. Physiol. 163:246-55, 1995

26.

27

Franklin RA, Tordai A, Mazer BD, Terada N, Lucas JJ, Gelfand EW:

Activation of MAP2-Kinase in B Lymphocytes by Calcium Ionophores.

J. Immunol. 153:4890-8, 1994

25.

390

Terada N, Patel HR, Takase K, Kohno K, Nairn AC, Gelfand EW:

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins.

Proc. Natl. Acad. Sci. USA 91:11477-81, Nov, 1994

24.

16

Takase K, Terada N, Szepesi A, Teraoka H, Gelfand EW, Lucas JJ:

Release from G0/G1 arrest induced by dimethyl sulfoxide in human lymphoid cells: Regulation of synthesis

and activation of the p34cdk2 and p34cdc2 kinases.

Cell Growth & Diff. 5:1051-9, 1994

23.

6

Or R, Renz H, Terada N, Gelfand EW:

Regulation of B-cell immune responses: Predominant role of IL-4 in triggering cell proliferation and Ig

production in competent B cells.

Clin. Immunol. Immunopathol. 72:141-9, 1994

22.

10

Patel HR, Renz H, Terada N, Gelfand EW:

Differential activation of p21ras in CD45RA+ and CD45RO+ human T lymphocytes.

J. Immunol. 152:2830-6, 1994

21.

381

Sato N, Sakamaki K, Terada N, Arai K, Miyajima A:

Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common

b subunit responsible for different signaling.

EMBO J. 12:4181-9, Nov, 1993

20.

143

Brodie C, Siriwardana G, Lucas JJ, Schleicher R, Terada N, Szepesi A, Gelfand EW, Seligman P:

Neuroblastoma sensitivity to growth inhibition by deferrioxamine: Evidence for a block in G1 phase of the

cell cycle.

Cancer Res. 53:3968-75, 1993

19.

46

Franklin RA, Mazer B, Sawami H, Mills GB, Terada N, Lucas JJ, Gelfand EW:

Platelet-activating factor triggers the phosphorylation and activation of MAP-2 kinase and S6 peptide kinase

activity in human B cell lines.

J. Immunol. 151:1802-10, 1993

18.

98

Terada N, Franklin RA, Lucas JJ, Blenis J, Gelfand EW:

Failure of rapamycin to block proliferation once resting cells have entered cell cycle despite inactivation of

p70 S6 kinase.

J. Biol. Chem. 268:12062-8, Jun, 1993

17.

8

Saloga J, Schwinzer R, Renz H, Terada N, Or R, Gelfand EW:

Characterization of the progression signal for human T-cell proliferation provided by monoclonal antibodies

to the CD3-TCR complex.


16.

48

Smith TJ, Terada N, Robinson CC, Gelfand EW:

Acute infectious mononucleosis stimulates the expansion of v6.1-3 and v7 T cells.

Blood 81:1521-6, 1993

15.

35

Terada N, Or R, Szepesi A, Lucas JJ, Gelfand EW:

Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T

lymphocytes.

Exp. Cell. Res. 204:260-7, 1993


22

14.

185

Terada N, Lucas JJ, Szepesi A, Franklin RA, Domenico J, Gelfand EW:

Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to

late G1 phase of the cycle.

J. Cell. Physiol. 154:7-15, 1993

13.

17

Terada N, Or R, Weinberg K, Domenico J, Lucas JJ, Gelfand EW:

Transcription of IL-2 and IL-4 genes is not inhibited by cyclosporin A in competent T cells.

J. Biol. Chem. 267:21207-10, 1992.

12.

21

Or R, Renz H, Terada N, Gelfand EW:

IL-4 and IL-2 promote human T-cell proliferation through symmetrical but independent pathways.


11.

74

Terada N, Lucas JJ, Szepesi A, Franklin RA, Takase K, Gelfand EW:

Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells.

Biochem. Biophys. Res. Commun. 186:1315-21, Aug, 1992

10.

36

Lucas JJ, Terada N, Szepesi A, Gelfand EW:

Regulation of synthesis of p34cdc2 and its homologues and their relationship to p110Rb phosphorylation

during cell cycle progression of normal human T cells.

J. Immunol. 148:1804-11, 1992

9.

25

Sawami H, Terada N, Franklin RA, Okawa H, Uchiyama T, Lucas JJ, Gelfand EW:

Signal transduction by interleukin 2 in human T cells: Activation of tyrosine and ribosomal S6 kinases and

cell-cycle regulatory genes.

J. Cell. Physiol. 151:367-77, 1992

8.

70

Terada N, Lucas JJ, Gelfand EW:

Differential regulation of the tumor suppressor molecules, retinoblastoma susceptibility gene product (Rb)

and p53, during cell cycle progression of normal human T cells.

J. Immunol. 147:698-704, 1991

7.

3

Terada N, Smith TJ, Stork LC, Odom LF, Gelfand EW:

N-ras gene mutations in childhood acute non-lymphoblastic leukemia.

Leukemia Res. 15:935-42, 1991

6.

19

Terada N, Miyoshi J, Kawa-Ha K, Sasai H, Orita S, Yumura-Yagi K, Hara J, Fujinami A, Kakunaga T:

Alteration of N-ras gene mutation after relapse in acute lymphoblastic leukemia.

Blood 75:453-7, 1990

5.

22

Yumura-Yagi K, Hara J, Terada N, Ishihara S, Tawa A, Takihara Y, Champagne E, Minden M, Mak TW,

Kawa-Ha K:

Analysis of molecular events in leukemic cells arrested at an early stage of T-cell differentiation.

Blood 74:2103-11, 1989

4.

28

Hara J, Yumura-Yagi K, Tawa A, Ishihara S, Murata M, Terada N, Izumi Y, Champagne, Takihara Y, Mak

TW, Minden M, Kawa-Ha K:

Molecular analysis of acute undifferentiated leukemia: Two distinct subgroups at the DNA and RNA levels.

Blood 74:1738-46, 1989

3.

3

Tawa A, Kawa-Ha K, Ishihara S, Yumura-Yagi K, Terada N, Murata M, Izumi Y, Yabuuchi H:

T-cell receptor chain gene expression in B-lineage acute lymphoblastic leukemia.

Cancer Science. 79:359-64, 1988

2.

NA

Terada N, Kawa-Ha K, Tawa A, Yagi-Yumura K, Ishihara S, Murata M, Izumi Y, Yabuuchi H, Tsujimoto Y:

The bcl-2 gene in childhood B-lineage acute lymphoblastic leukemia.

J. Clin. Exp. Med. (医学のあゆみ in Japanese), 144:643-4, 1988

1.

10

Taenaka N, Terada N, Takahashi H, Tachimori Y, Okada T, Takezawa J, Shimada Y, Yoshiya I:

Hemodialysis using gabaxate mesilate (FOY) in patients with a high bleeding risk.

Crit. Care. Med. 14:481-3, 1986


23

Reviews, Book Chapters, Editorial:

No. Times

Cited

Authors, Title, Journal, Volume, Pages, Year

30.

0

Bai F, Li Z, Umezawa A, Terada N, Jin S:

Bacterial Type III Secretion System as a Protein Delivery Tool for a Broad Range of Biomedical

Applications

Biotechnol. Adv. 36:482-93, Mar, 2018 [PMID 29409784]

29.

1

Wallet MA, Santostefano KE, Terada N, Brusko TM:

Isogenic Cellular Systems Model the Impact of Genetic Risk Variants in the Pathogenesis of Type 1

Diabetes

Front. Endocrinol. 8:276, Oct, 2017 [PMID:29093700]

28.

0

Watanabe N, Santostefano KE, Yachnis AT, Terada N:

A pathologist’s perspective on induced pluripotent stem cells

Lab. Invest. 97:1126-32, Oct, 2017 [PMID: 28759008]

27.

3

Relling MV, Krauss RM, Roden DM, Klein TE, Fowler D, Terada N, Lin L, Riel-Mehan M, Kubo M, Yee SW,

Johnson G, Giacomini KM:

The New Pharmacogenomics Research Network (PGRN): An open community catalyzing research and

translation in precision medicine

Clin. Pharmacol. Ther. 102:897-902, Dec 2017 [PMID:28795399]

26.

14

Hamazaki T, El Rouby N, Fredette NC, Santostefano KE, Terada N:

Concise Review: Induced pluripotent stem cell research in the era of precision medicine

Stem Cells 35:545-50, Mar, 2017 [PMID:28100040]

25.

10

Kilberg MS, Terada N, Shan J:

Influence of amino acid metabolism on embryonic stem cell function and differentiation

Adv. Nutr. 7:780S-789S, Jul, 2016 [PMID:27422515]

24.

40

Santostefano KE, Hamazaki T, Biel NM, Jin S, Umezawa A, Terada N:

A practical guide to induced pluripotent stem cell research using patient samples

Lab. Invest. 95:4-13, Jan, 2015 [PMID:25089770]

23.

9

Newby B, Terada N, Mathews CE:

In search of a surrogate: Engineering human beta cell lines for therapy

Trends Endocrinol. Metabol. 25:378-80, Aug, 2014 [PMID:24958526]

22.

NA

Hamazaki T, Terada N:

What to be rejuvenated through cellular reprogramming? - Things to consider before jumping on the iPS

cell bandwagon for aging research

Anti-Aging Med. (アンチ・エイジング医学 in Japanese) 8:404-10, June, 2012

21.

NA


Disease iPS cells from patients and for patients

Exp. Med. (実験医学 in Japanese) 30:1683-7, June, 2012

20.

NA


Current Opinion in patient iPS cell-based disease modeling

J. Clin. Exp. Med. (医学のあゆみ in Japanese) 239:1371-6, Dec, 2011

19.

1

Hankowski KE, Terada N:

An Ezh way to turn off Nanog (News & Views)

Cell Cycle 10:2253-4, July, 2011


24

18.

23

Hankowski KE, Hamazaki T, Umezawa A, Terada N:

Induced pluripotent stem cell as a next generation biomedical interface

Lab. Invest. 91:972-7, July, 2011 [PMCID: PMC3727242]

17.

2

Crawford JM, Ketcham CM, Braylan RC, Morel L, Terada N, Turner JR, Yachnis AT:

The Publishing Game: Thoughts of an Editorial Team

Lab. Invest. 88:1258-63, Dec, 2008 (Covered Article)

16.

20

Singh AM, Terada N:

Bypassing heterogeneity: the road to embryonic stem cell-derived cardiomyocyte specification.

Trends Cardiovasc. Med. 17:96-101, Apr, 2007 (Covered Article)

15.

17

Oka M, Chang L-J, Costantini F, Terada N:

Lentiviral vector-mediated gene transfer in embryonic stem cells.

In Turksen K, ed. “Embryonic Stem Cell Protocols: Volume I: Isolation and Characterization, Second

Edition” Humana Press, Totowa, New Jersey

Methods Mol. Biol. 329:273-82, Feb, 2006

14.

62

Rodic N, Rutenberg MS, Terada N:

Cell fusion and reprogramming: Resolving our transdifferences

Trends Mol. Med. 10:93-6, Mar, 2004 (Covered Article)

13.

41

Rutenberg MS, Hamazaki T, Singh AM, Terada N:

Stem cell plasticity, beyond alchemy

Int. J. Hematol. 79:15-21, Jan, 2004

12.

NA

Lucas JJ, Terada N:

Chapter 14: Spontaneous cell fusion

In Lanza R et al. Ed. “Adult and Fetal Stem Cells (Vol. 2)” Elsevier Academic Press

Handbook of Stem Cells 2:153-8, 2004

11.

20

Lucas JJ, Terada N:

Cell fusion and plasticity

Cytotechnology 41:103-9, 2003 [PMCID: PMC3466689]

10.

25


In vitro differentiation of embryonic stem cells into hepatocytes

Methods Enzymol. 365:277-87, 2003

9.

NA

Kawasome H, Hamazaki T, Minamino T, Terada N:

Signal transduction study using gene-targeted embryonic stem cells.

In Terrian DM, ed. “Cancer Cell Signaling” Humana Press, Totowa, New Jersey

Methods Mol. Biol. 218:35-46, 2003

8.

NA

Mastalerz DM, Terada N:

An “Identity Crisis” for Stem Cells

Directions in Science 1:96-8, 2002

7.

NA

Terada N:

Cell fusion shows a trick of stem cell magic?

Cell Technology (細胞工学 in Japanese) 21:648-9, 2002

6.

31

Petersen BE, Terada N:

Stem cells: A journey into a new frontier

J. Am. Soc. Nephrol. 12:1773-80, 2001 (Covered Article)

5.

NA

Terada N: Cell cycle regulatory genes and malignant tumors: Basic and clinical studies of INK4a.

Jpn. J. Ped. Hematol. (小児血液学雑誌 in Japanese) 11:1-13, 1996.


25

4.

NA

Terada N: Enigma of The Immunosuppressive Drug, Rapamycin.

Seikagaku (生化学 in Japanese) 67:1241-5, 1995

3.

NA

Terada N: S6 kinase and translational regulation of mRNAs encoding ribosomal proteins.

Exp. Medicine (実験医学 in Japanese) 13:442-5, 1995

2.

4

Terada N, Franklin RA, Lucas JJ, Gelfand EW:

T-cell signalling and activation through the IL-2 receptor complex:

In"Growth Factors and Signal Transduction in Development" Nilsen-Hamilton M., ed. New York, NY:

John Wiley & Sons, Inc. pp75-95, 1994

1.

NA

Terada N, Kawa-Ha K:

Mixed lineage leukemia (biphenotypic leukemia).

Annual Review Ketsueki 1988 (in Japanese), pp65-71, 1988

Documents

Curriculum Vitae Naohiro Terada, M ... - College of Medicine · Veterinary Medicine, University of Florida License: Japanese Medical License, Registration No. 260174 Professional