Curriculum Vitae March, 2019 Claire E. Hulsebosch, Ph.D. · Curriculum Vitae . March, 2019 . Claire E. Hulsebosch, Ph.D. PRESENT TITLE: Adjunct Professor of Neurobiology and Anatomy

Curriculum Vitae

March, 2019

Claire E. Hulsebosch, Ph.D. PRESENT TITLE: Adjunct Professor of Neurobiology and Anatomy University of Texas McGovern Medical School at Houston ADDRESS: Department of Neurobiology and Anatomy 6431 Fannin St., MSB 7.047

Houston, Texas 77030 713-500-5090 tel

E-mail: [email protected] CITIZENSHIP: USA UNDERGRADUATE EDUCATION:

B.A. (Biology, English, Education), 1974 Rice University Houston, Texas GRADUATE EDUCTION: Ph.D. (Zoology, Neuroscience), 1979 University of Texas at Austin Austin, Texas POSTGRADUATE TRAINING: NIH Postdoctoral Fellowship Award, 1979-1982 Postdoctoral Fellow, Richard Coggeshall mentor Marine Biomedical Institute University of Texas Medical Branch Galveston, Texas ACADEMIC APPOINTMENTS: 1974-1975 Teaching Assistant I (Biological Processes) University of Texas, Austin, Texas 1975-1977 Research Scientist II, Cell Research Institute, University of Texas, Austin, Texas

C.E. Hulsebosch, Ph.D. 2

1977-1979 Assistant Instructor (Vertebrate Physiology, Human Physiology), University of Texas, Austin, Texas 1979-2004 Associate Member, Marine Biomedical Institute, University of Texas Medical Branch, Galveston, Texas 1980-1982 Instructor (Gross Anatomy), Department of Anatomy, University of Texas Medical Branch, Galveston, Texas 1982-1985 Research Assistant Professor of Anatomy, Department of Anatomy,

University of Texas Medical Branch, Galveston, Texas 1986-1989 Assistant Professor of Anatomy & Neurosciences, Department of

Anatomy & Neurosciences, University of Texas Medical Branch, Galveston, Texas

1989-1994 Associate Professor of Anatomy & Neurosciences, Department of

Anatomy & Neurosciences, University of Texas Medical Branch, Galveston, Texas

1994-2004 Professor of Anatomy & Neurosciences, Department of Anatomy &

Neurosciences, University of Texas Medical Branch, Galveston, Texas

2004-2014 Vice-Chair and Professor, Department of Neuroscience and Cell

Biology, University of Texas Medical Branch, Galveston, Texas 2008-2014 Claire E. Hulsebosch, Ph.D. Chair in Neurological Recovery 2013-present Adjunct Professor Department of Neurobiology and Anatomy University of Texas Health Science Center at Houston, Houston,

Texas CERTIFICATION: State of Texas Secondary Certificate of Education PROFESSIONAL ORGANIZATIONS: National Committee for Women in Neuroscience, 1986 - present Ad Hoc Reviewer, NINDS Program Project Review Committee, Jan., 1990, 1993,

1997-present NINDS Training Grants – Sept. 2001 - present NINDS Program Project Review Committee A July 1, 1993 - June 30, 1997 NINDS Underrepresented Minorities Program-Review Committee. 2001 – 2012 Craig Neilsen Foundation Scientific Review Committee, 2008-present New Jersey Spinal Cord Injury Scientific Advisory Board, 2003-present. Christopher Reeves Paralysis Foundation Scientific Advisory Board, 1997- present


Scientific Advisory Board - Kent Waldrep Foundation, 1993 - 2004 Program Committee, Restoration of Neural Control after Spinal Cord Injury:

Responding to the New Anatomy, Biomedical Engineering Research, Feb. 8-9, 1996 Program Committee, Neurotrauma Society, 14th Annual Mtg., Nov. 15-16, 1996 Women in Neurotrauma Research, 1995-present Founding Member of Mission Connect, 1995 Mission Connect Advisory Committee, 1997 – present National Neurotrauma Society Councilor, 1997-2001 Mission Connect, Director of Spinal Cord Injury Research, 1998-present President, Women in Neurotrauma Research, 1999-2001 President’s Research Advisory Committee for the Center of Excellence on Healthy

Aging with Disabilities, 1997-2003 Basmajian/Williams & Wilkins Award Committee, 2001 – 2004 National Neurotrauma Society President-Elect, 2003-2004 Director, Research for Mission Connect, 2003 – 2007 National Neurotrauma Society President – 2005 Program Committee, National Neurotrauma Society-2002-present National Neurotrauma Society Councilor-2010-2015 Editor, J. of Developmental Neurosc., 1996-2002 Editor, Journal of Neurotrauma, 2003 – present Guest Editor, Experimental Neurology, 2010-2014 UNIVERSITY OF TEXAS MEDICAL BRANCH UNIVERSITY COMMITTEES: UTMB Faculty Women’s Club, 1986 - 2014 Program Director - Spinal Cord Injury Research Consortium Graduate School Curriculum Committee, 1992 – 2014 Neuroscience Graduate Program Committees, 1983-2015 Cell Biology Graduate Program Committees, 1986-2014 Medical School Gross Anatomy Course Committee, 1980 – 2014 Medical School Neurobehavioral Course Committee, 1980-2014 Research Council, 1997 - 2000 Admissions Committee Interviewer, 1983 - 2014 Judge - National Research Forum, 1987 - 2014 4th Year Medical Student Assessment Exercise, 1987-1999 Chairman – Medical Student Honors and Awards Committee, 1994 – 2014 Deans Research Advisory Committee, 1997-1999; 2004 Nominating Committee, 1999 - 2014 Core Committee on the Status of Women Faculty and Administrators, 2001-2004 Dean’s Basic Science Committee, 2003 Academic Review Committee – School of Medicine, 2003 – 2014 President’s Faculty/Staff Campaign Planning Committee , 2003- 2014 Medical Student Grievance Committee, 2004-2007 Ophthalmology Chair Search Committee, 2003 – 2004 Research Buildings Facilities Committee-2005-2006 Dean’s Search Committee for Director of Research, 2005 Internal Medicine Chair Search Committee, 2005-2008 Faculty Performance Evaluation Committee, July 1, 2005-2014


Oslerian Master Advisor for MS1s-2005-2013 UNIVERSITY OF TEXAS MEDICAL BRANCH DEPARTMENT OR GRADUATE SCHOOL PROGRAM COMMITTEES: Evaluation and Development Committee, 1995-2013 Appointment, Promotion and Tenure Committee, Chair, 1993-2013 Curriculum and Advisory Committee Cell Biology, Chair, 1992-1993 Seminar Committee, Chairman, 1992-2014 Executive Committee, Cell Biology Graduate Program, 1992-1993 Health and Safety Committee for Ultrastructure Division, 1993-1995 Computer Committee for Personnel, Management and Education, 1986-2002 Image Analysis Committee Molecular Biology Committee, 1996-2002 Vice Chair, Executive Committee, 2004-2014 HONORS AND AWARDS: Jesse H. Jones and Mary Gibbs Jones Scholarship, 1970-1974 Rice President's Honor Roll, 1973-1974 Kappa Kappa Gamma Fellowship, 1977 University of Texas Grant-in-Aid Research Funds, 1978 University of Texas Grant-in-Aid Travel Funds, 1978 Nominated and Accepted to Phi Kappa Phi, 1978 Alternate for Sigma Delta Epsilon Grant-in-Aid Award, 1977 National Paralyzed Veterans (Houston Chapter) Scholarship, 1979 National Institutes of Health Postdoctoral Fellowship, 1979-1982 Research Career Development Award, 1988-1993 Basmajian/Williams and Wilkens Award, 1989 Jimmy Doyle Dickens Memorial Faculty Award, 1993 Dean’s Teaching Award UT Houston Medical School, 2013-2014 Dean’s Teaching Award UT Houston Medical School, 2014-2015 Best Basic Science Professor for First Year Medical School, 2015 Dean’s Teaching Award UT Houston Medical School, 2015-2016 Dean’s Teaching Award McGovern Medical School, 2016-2017 Student Marshall, Graduating Medical Class of 2017 Reeve-Irvine Research Medal for Seminal Contributions in Spinal Cord Injury, 2017 Student Marshall, Graduating Medical Class of 2018 John H. Freeman Outstanding Teacher Award, 2018 UNIVERSITY OF TEXAS MEDICAL BRANCH TEACHING RESPONSIBILITIES: Medical School Gross Anatomy: Lecture and Lab Neuroscience: Lecture and Lab Graduate School


Graduate Neurosciences Current Topics Course Molecular Neurobiology Research Techniques - Course Director Critical Reading Course in Neural Injury and Diseases – Course Director Neurobiology of Diseases Integrative Neuroscience Supervisory Professor for the Following Candidates for Ph.D. Bethany A. Urschel, In vivo effects of nerve growth factor suppression on glial-neuronal

interactions and nerve growth factor receptor distribution. 1987-1991 Robert Paul Stroemer, Neuronal remodeling and behavioral recovery following cortical

infarction.1990-1994 Marc D. Christensen, Intraspinal sprouting after spinal hemisection and intrathecal delivery

of neurotrophins. 1992-1996. Edward A. Zompa, Migration and differentiation of neuronal cell lines transplanted into the

injured spinal cord. 1992-1997. Adrianne D. Bennett, Mechanisms of chronic central pain after spinal cord injury. 1995-2000 Bryan C. Hains, Transplant therapy for chronic central pain in spinal cord injury. 1997-2001 Charles D. Mills, The role of metabotropic glutamate receptors in spinal cord injury.

1998-2002 Huaiyu Tan, Glutamate receptors and chronic pain in spinal cord injury. 2001- 2006 Michael Carter, Anti-inflammatory treatments for spinal cord injury. 2002 - 2006 Brian Rooney, Decorin and improved bladder and bowel function after spinal cord

injury. 2003-2010 Shayne Hassler, Role of reactive oxygen species in lipid peroxidation and chronic pain after

spinal cord injury, 2009-2014 Supervisory Professor for the Following Medical Students in Research Program Desmar Walkes, Central nervous system localization of I125 NGF, 1982. Denise Greenwood, Sexual dimorphism in the pelvic ganglia of rats, 1983. Dalton Heath, Axon and neuron numbers after forelimb amputation in neonatal rat, 1984. Harris Baden, Paradoxical sprouting of ventral root unmyelinated fibers after ANTI-NGF

treatment, 1986. Brad Gurwitz, Lack of sprouting in the CNS after forelimb amputation, 1987. Darren Hamm, Origin of ANTI-NGF induced intraspinal sprouting, 1988. Patrick N. Brown, Directional effects of ANTI-NGF on sensory neurons in vivo, 1988. James Yegge, Ontological response of primary afferent sprouting to isogeneic antibodies

on Nerve Growth Factor, 1989. Yen Chou Joe Chen, Maternal antibodies access the neonatal CNS, 1990. John K. Dorman, Mammalian spinal tract regeneration, 1991. Edward A. Zompa, Cultured cell lines as transplant sources after lesion in the spinal cord, 1992. Chance W. Dingler, Human neurons used in transplant therapy after cortical injury, 1992. Ping-Sun Chen, Clinical application of Nerve Growth Factor (NGF) or antibodies to NGF may alter nociceptive thresholds, 1992. Margot Garcia, Gene expression in peripheral nerve grafts, 1993.


Jason Pickelman, Recovery of sensory and motor function following spinal cord hemisection, 1994. Son Wang, Hybridization studies of dorsal root ganglia following spinal cord hemisection, 1995. William D. Nicholson, Fine fiber projections to the dorsal horn. An HRP study, 1995. Tray Mattison, DRG CGRP mRNA regulation following spinal hemisection, 1995. Chris Sherman, Measures of chronic pain in spinal cord injury, 1996. Fillomeno Gonzales, Changes in spontaneous activity reflect chronic pain after spinal cord

injury,1998. Huaiyu Tan, Electrophysiology of spinal cord, 1999. Rachel McConnell, GABA expression in spinal cord injury, 2001. James Finklea, Cold allodynia after spinal cord injury, 2001. Michael Carter, LIF treatment for inflammation after spinal cord injury, 2001. J. Kaleb Shaw, Novel treatment for spinal cord injury, 2003 Katherine Kinter, Bladder and bowel function after spinal cord injury, 2005 Supervisory Professor for the Following College Students in Research Program Frank SiFuentes, St. Edward's University, Survival of severed distal axons in the mammal, 1991. Audra L. Welch, San Angelo University, Access of maternal antibodies to developing neonatal central nervous system, 1992. Alberto Montero, University of Texas at Austin, Penetrability of subarachnoid molecules delivered to the lumbar spinal cord, 1993. Diane Chico, St. Edward's University, Expression of growth associated protein after cortical

infarction, 1993. Laurel Fohn, San Angelo State University, Expression of calcitonin gene-related peptide

following spinal hemisection, 1994. Mitra Ziania, University of Houston, Thermal hyperalgesia following spinal hemisection: a

model of central pain, 1994. Adrianne Bennett, University of California, Santa Cruz, Chronic pain model of spinal cord

injury, 1995. Supervisory Professor for the Following Secondary Students Jacqueline Lebow, Leonard I. Wiener Secondary School, Comparison and contrast between neonatal and adult spinal cord, 1991. Jackie Gonzalez, Ball High School, Immunoreaction as a technique in neuroscience, 1991. Jacqueline Lebow, Leonard I. Wiener Secondary School, Fetal alcohol syndrome, 1992. James Gipson, Ball High School, Observe peripheral nerve transplants after spinal cord injury, 1992. Jason Zendeh Del, Ball High School, Research approaches to spinal cord injury, 1996. Collin Sherrill, 3-D Spinal cord reconstruction, 1998-2000 Jonathan Daum, Memorial High School, Cytology of spinal cord injury, 2000. Jennifer Yurca, Ball High School, Selective inhibition of cox-2 improves function after spinal cord injury, 1999-2001. UNIVERSITY OF TEXAS MCGOVERN MEDICAL SCHOOL AT HOUSTON


COMMITTEES: Neurobehavioral Curriculum Revision Committee Foundations Curriculum Revision Committee Human Development Revision Committee Human Gross Anatomy Revision Committee Presubmission Grant Reviewer, 2013-present Medical Student Applicant Faculty Advocate Master Advisor to MS1s 2013-2016 Faculty Affiliate to McGovern Societies 2016-present Renal Module Committee 2016-present Cardiovascular Module Committee 2016-present Pulmonary Module Committee 2016-present Reproduction Module Committee 2016-present Endocrine Module Committee 2016-present Nervous System and Behavioral Module (NSB) 2015-present NSB Co-Module Director 2017-present CURRENT TEACHING RESPONSIBLITIES: Medical School Gross Anatomy, laboratory 2013- present Medical School Gross Anatomy lecturer, as needed 2013-present Medical School Human Developmental Anatomy, lecturer 2013-present Medical School Human Developmental Anatomy, Course Director, 2015 Medical School Neuroscience, lecturer and laboratory 2013-present Medical School MSIV Senior Anatomy Elective, 2013-present Problem Based Learning Fascilitator, Spring-2016-present Graduate School, Intro to Cognitive Neuroscience, lecturer 2014-present RESEARCH ACTIVITIES: Area of Research Mammalian spinal cord organization, development and regeneration; central nervous

system plasticity; neural transplant models; traumatic brain injury, evaluation of molecular markers of axonal sprouting and synaptogenesis of the cortex following infarction and their correlation to recovery from behavioral dysfunction; gene expression in CNS trauma; intracellular signaling mechanisms of persistent pain.

GRANT SUPPORT: Frank A. Liddell Fund of the Greater Houston Community Foundation “Recovery of Pelvic Visceral Function after SCI” Claire E. Hulsebosch, P.I. ($200,000, 7/24/04 – 7/23/15)


DoD, C.E. Hulsebosch and J.R. Perez-Polo, Co-I’s “Mission Connect TBI Translational Research Consortium”; $336,693; 08/01/08 – 07/31/14

NS 06246: The Innervation and Reflex Control of the Bladder (total of $51,776,

7/1/79 -6/30/82) UTMB Intramural Grant: Quantitation of Axonal Sprouting in the Presence of Nerve

Growth Factor (total of $9,900, 4/1/83 - 3/31/84) NS 20091: Quantitation of Axonal Sprouting in the Presence of Nerve Growth Factor

(total of $100,231, 7/1/83 - 12/31/87) Paralyzed Veterans of America and American Paralysis Association: Axon

Regeneration in the Mammalian Spinal Cord in Response to Surgical Denervation and Nerve Growth Factor (total of $24,640, 9/1/84 - 8/31/85)

Spinal Cord Research Foundation: Axon Regeneration in the Mammalian Spinal

Cord in Response to Surgical Denervation and Nerve Growth Factor (total of $25,276, 7/1/86 - 6/30/87)

Spinal Cord Research Foundation: Spinal Cord Synaptogenesis in Response to

Deafferentation and Alterations in Nerve Growth Factor (total of $29,070, 8/1/87 -7/31/88)

NS 25450: Small Instrumentation Grant (total of $18,896, 9/1/87 - 8/31/88) PR 03979: Image Processing and Analysis System, J.D. Bottenstein, P.I., C.E.

Hulsebosch, Co-P.I. (total of $115,735, 5/1/88 - 4/30/89) NS 11255: Comparative Neurobiology of the Spinal Cord, W.D. Willis, Program

Director; Project 2 - Nerve Growth Factor: Axonal and Synapse Changes in the Spinal Cord, C.E. Hulsebosch, Principal Investigator (total project award: $256,397; current year $48,121, 8/1/86 -7/31/91)

NS 11255: Comparative Neurobiology of Spinal Cord, W.D. Willis, Program Director;

Project 8 - Molecular Mechanisms of Sprouting in the Spinal Cord, (total project award: $208,359; current year $45,133, 8/1/91 - 7/31/96)

NS 11255: Chronic Pain after Spinal Cord Injury (Project 7), W.D. Willis, Program

Director; Project 7 - Molecular Mechanisms of Sprouting in the Spinal Cord, (total project award: $427,880; current year $75,904, 8/1/96 - 7/31/01)

CA 53742: Small Instrumentation Grant (total of $12,717; 9/1/90 - 8/31/91) The Moody Foundation, The Study of a New Neuronal Cell Line for Transplantation,

Howard Eisenberg, M.D., Project Director, (total project award: $544,869) Morphology Core, Co-P.I.'s K. Westlund High, C.E. Hulsebosch


Unrestricted Pain Center Grant, Bristol-Myers-Squibb Co., W.D. Willis, P.I., C.E.

Hulsebosch Co-P.I. (total award: $250,000) NS 01217: RCDA Molecular Mechanisms of Sprouting in the Spinal Cord, (total

project award: $235,313; funds salary of P.I., current year $63,969, 08/01/88 - 07/31/93)

Spinal Cord Research Foundation 1732-01: Reduction of Chronic Pain After SCI, C.E. Hulsebosch, P.I. (total project $49,680, 7/1/97 – 12/31/99) Spinal Cord Research Foundation #1818: Pilot Consortium: Mechanism of Chronic Pain Induced by Excitotoxicity Following Spinal Cord Injury, C.E. Hulsebosch, P.I. (total $100,000, 01/01/98 – 06/30/00)

Texas Neurofibromatosis Foundation: Developmental Control of Schwann Cells in

Neurofibromatosis, (total $12,000, 04/1/91 - Open) Kent Waldrep National Paralysis Foundation: Fellowship in Spinal Cord Injury, (total

$86,382, 8/10/94 - open)

Mission Connect – The Institute for Rehabilitation and Research, C.E. Hulsebosch, Program Director – Mechanism of chronic pain induced by excitotoxicity ($300,000, 6/1/98 – 12/31/07)

NS 39161: Chronic Pain in Spinal Cord Injury (Project 1 and Core A), Claire E. Hulsebosch, Program Director and PI of Project 1 “Intervention in the Development of Chronic Central Pain after Spinal Cord Injury” Project 1, 20% effort; $154,051; Core A, 15% effort; $107,103, 01/11/01 – 12/31/07

NS11255-27A1: Pain and Inflammation, Project 4, (Co-I with McAdoo) The Role of Leukemia Inhibitory Factor and Nerve Growth Factor in Inflammation and Chronic

Pain after Spinal Cord Injury; Core C – Imaging. Project 4, 20% effort; $205,459; Core C, 5% effort; $49,047, 08/01/01 – 07/31/08

"Use of PC-NSAID's in Chronic Pain" 11/23/04 - 11/22/08; 10% effort; $201,381 Subaward from UT Health Science Center Houston on Army W81XWH-05-1-0118 John S. Dunn Research Foundation 2/1/03 – 2/13/10 $50,000 Gift for Spinal Cord Research designated for Dr Claire Hulsebosch. The West Endowment 02/09/05 - 02/08/10 $50,000 A grant for Dr Claire Hulsebosch for the Spinal Cord Injury Research Consortium, a part if the Mission Connect Project.


NS054765: Peripheral Sensitization Following Spinal Cord Injury (Carlton, PI; Hulsebosch, Co-I) 10% effort, $250,000, 08/01/07 – 07/31/12 NS11255-32A2: Pain and Inflammation, Project 1 “The Role of Reactive Oxygen Species in Central Neuropathic Pain” $168,300; 04/01/08 – 03/31/14 NS11255-32A2: Pain and Inflammation, Imaging Core C; $37,903; 04/01/08 – 03/31/14

ADDITIONAL INFORMATION: Membership in Scientific Societies: National Neurotrauma Society* American Society for Neurochemistry* American Association of Anatomists* Cajal Club* Society for Neuroscience* American Association for the Advancement of Science Texas Society of Electron Microscopy International Society for Developmental Neuroscience (ISDN) International Association for the Study of Pain* American Pain Society* Winter Conference for Brain Research* American Paraplegia Society* (* denotes elected membership) Scientific Advisory and Review Boards: InCell Research Center of Excellence on Healthy Aging with Disabilities Kent Waldrep National Paralysis Foundation Mission Connect – The Institute for Rehabilitation and Research Spinal Cord Research Foundation Kentucky Spinal Cord and Head Injury Research Initiative Christopher and Dana Reeves Paralysis Foundation Craig Neilsen Foundation National Editor: International J. of Developmental Neuroscience J. of Neurotrauma Reviewer - Grants: National Institutes of Health - NINDS National Science Foundation


Spinal Cord Research Foundation Veterans Administration Department of Defense American Paralysis Association Research Council of Canada Hong Kong Research Grants Council Kentucky State Spinal Cord Injury Initiative New Jersey State Spinal Cord Injury Initiative Christopher and Dana Reeves Paralysis Foundation Craig Neilsen Foundation Reviewer - Journals: Nature Nature Neuroscience J. Neuroscience J. Comparative Neurology J. Neuroscience Research Neuroscience Letters Experimental Neurology Experimental Brain Research International J. of Developmental Neuroscience American Journal of Physiology Anesthesia and Analgesia Brain Research Pain J. of Pain J. Neurochemistry Science J. of Neuropharmacology Spine J. of Spinal Cord Medicine PUBLICATIONS: A. Abstracts/Presentations: 1. Hulsebosch, C.E. Radioautographic studies of friend leukemia virus--containing murine

cells. Texas Soc. for Electron Microscopy Newsletter 8(2): 26, 1977. 2. Hulsebosch, C.E. An ultrastructural study of the ventral nerve cord of Clymenella

torquata. Texas/Louisiana Soc. for Electron Microscopy Newsletter 9(1): 28, 1977. 3. Hulsebosch, C.E. and Bittner, G.D. A comparative study of CNS neuron regenerative

abilities. Neurosci. Abstr. 4: 532, 1978. 4. Hulsebosch, C.E. and Bittner, G.D. A study of neural somata regeneration - A test of the


neuron addition hypothesis. Neurosci. Abstr. 5: 678, 1979. 5. Hulsebosch, C.E. and Coggeshall, R.E. Categories of axons in bladder nerves.

Neurosci. Abstr. 6: 115, 1980. 6. Hulsebosch, C.E. and Coggeshall, R.E. Sprouting of dorsal root axons. Cajal Club, April,

1981. 7. Hulsebosch, C.E. and Coggeshall, R.E. Sprouting of dorsal root axons after unilateral

rhizotomy. Anat. Rec. 199: 122A, 1981. 8. Hulsebosch C.E. and Coggeshall, R.E. Sprouting of unmyelinated dorsal root axons in

response to spinal or dorsal root injury. Third World Congress on Pain, 1981. 9. Hulsebosch, C.E. and Coggeshall, R.E. Origin of axons in the bladder nerves. Neurosci.

Abstr. 7: 214, 1981. 10. Coggeshall, R.E. and Hulsebosch, C.E. Sprouting of dorsal root axons following

neuronal injury. Neurosci. Abstr. 7: 37, 1981. 11. Hulsebosch, C.E. and Coggeshall, R.E. Effects of age on sprouting of dorsal root axons.

Neurosci. Abstr. 8: 307, 1982. 12. Steinman, J.L., Carlton, S.M., Hulsebosch, C.E., Coggeshall, R.E. and Willis, W.D.

Neural projections from genital tract in female rats: Axonal composition and segmental distribution. Neurosci. Abstr. 9:, 1983.

13. Hulsebosch, C.E., Perez-Polo, J.R. and Coggeshall, R.E. Axonal sprouting involves

nerve growth factor. Neurosci. Abstr. 9:, 1983. 14. Hulsebosch, C.E., Perez-Polo, J.R. and Coggeshall, R.E. Antibodies to nerve growth

factor increases sensory axon numbers in vivo. Neurosci. Abstr. 10: 1020, 1984. 15. Coggeshall, R.E., Chung, K. and Hulsebosch, C.E. Changes in numbers of dorsal root

axons during development. Neurosci. Abstr. 10: 1157, 1984 16. Hulsebosch, C.E., Perez-Polo, J.R. and Coggeshall, R.E. Antibodies to nerve

growthfactor differentially affect dorsal root ganglion neurons in vivo. Neurosci. Abstr. 11: 915, 1985.

17. Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R. Persistence of sprouting after

Anti-NGF treatment. XIX WCBR, 1986. 18. Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R. In vivo persistence

ofAnti-NGF induced mammalian sensory axons. International Symposium on NGF and Related Substances, 1986.

19. Hulsebosch, C.E., Perez-Polo, J.R. and Coggeshall, R.E. Persistence of Anti-NGF

induced dorsal root axons: Possible penetration in the mammalian spinal cord. Neurosci.


Abstr. 12: 511, 1986. 20. McNeill, D.L. and Hulsebosch, C.E. Intraspinal sprouting of primary

afferentsdemonstrated by FRAP. Cajal Club, 1987. 21. McNeill, D.L., and Hulsebosch, C.E. Sprouting by primary afferent fibers in laminae I and

II utilizing the molecular marker FRAP. Amer. Assoc. Anat. Abstr., Anat. Rec., 1987. 22. McNeill, D.L. and Hulsebosch, C.E. Intraspinal sprouting of rat primary afferents after

deafferentation. Neurosci. Abstr. 13: 1392, 1987. 23. Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R. Axonal sprouting in Lissauer's

tract in ANTI-NGF treated rats. Neurosci. Abstr. 13: 1014, 1987. 24. Coggeshall, R.E., Bolender, R.P., Chung, K., Hulsebosch, C.E. and McNeill, D.L. Mean

synaptic lengths of laminae I-IV in the rat dorsal horn are not homogeneous. Neurosci. Abstr. 13: 313, 1987.

25. Hulsebosch, C.E., Murray, M., Levine, R.B. and McNeill, D.L. Extrinsic factors affecting

synaptogenesis in central nervous systems. Winter Conference on Brain Research, 1988.

26. Fabian, R.H. and Hulsebosch, C.E. Penetration of systemically administered IgG into

the rat neonatal brain parenchyma. Amer. Assoc. Neurol. 1988. 27. Hulsebosch, C.E. and Carlton, S.M. Intraspinal synaptogenesis of primary afferent fibers

involves NGF. Neurosci. Abstr. 14: 687, 1988. 28. Fabian, R.H. and Hulsebosch, C.E. Time course of the penetration of systemically

administered IgG into the rat neonatal brain parenchyma. Neurosci. Abstr. 14: 1036, 1988.

29. McNeill, D.L., Coggeshall, R.E., Carlton, S.M. and Hulsebosch, C.E. Increases in CGRP

immunoreactivity in laminae I and II following chronic spared root deafferentation are due to an increase in terminal number not terminal size. Neurosci. Abstr. 14: 514, 1988.

30. Urschel, B.A. and Hulsebosch, C.E. Schwann cell-neuronal interactions involve NGF.

Neurosci. Abstr. 14: 518, 1988. 31. Coggeshall, R.E., Chung, K., Hulsebosch, C.E. and McNeill, D.L. Numbers of synapses

in laminae I-IV of rat dorsal horn. 101st Meeting of the Amer. Assoc. Anat. Abstr., Anat. Rec. 24A, 220: 4, 1988.

32. Baden, H.P., Brown, P.N., Hamm, D.E. and Hulsebosch, C.E. Nerve growth factor

deprivation induces intraspinal and directional sprouting of primary afferents in vivo. 102nd Meeting of the Amer. Assoc. Anat. Abstr. Anat. Rec. 10A, 223: 4, 1989.

33. Stamps, W.T., Coggeshall, R.E. and Hulsebosch, C.E. Three dimensional analysis of

synaptic discs in normal and deafferented laminae I-IV of rat dorsal horn. 102nd Meeting


of the Amer. Assoc. Anat. Abstr., Anat. Rec. 110A, 223: 4, 1989. 34. Urschel, B.A. and Hulsebosch, C.E. NGF deprivation arrests normal myelination. 102nd

Meeting of the Amer. Assoc. Anat. Abstr., Anat. Rec. 118A, 223: 4, 1989. 35. Cowan, R., Hulsebosch, C.E. and Carlton, S.M. Differential depletion of CGRP

immunostaining in the dorsal horn following forelimb amputation at birth. 102nd Meeting of the Amer. Assoc. Anat. Abstr., Anat. Rec. 27A, 223: 4, 1989.

36. Hulsebosch, C.E. and Carlton, S.M. Intraspinal synatogenesis of CGRP primary

afferents induced by nerve growth factor deprivation. Neurosci. Abstr. 15: 1388, 1989. 37. Urschel, B.A. and Hulsebosch, C.E. Recovery of impaired Schwann cell - neuronal

interaction due to NGF deprivation. Neurosci. Abstr. 15: 1359, 1989. 38. Gurwitz, B.W. and Hulsebosch, C.E. Absence of intraspinal sprouting after neonatal

amputation. Eighth Annual Meeting of the American Pain Society, Abstr. 1989. 39. Urschel, B.A. and Hulsebosch, C.E. Anatomical basis for altered somatosensory

sensations involving NGF. Eighth Annual Meeting of the American Pain Society, Abstr. 1989.

40. Hulsebosch, C.E. and Carlton, S.M. Axonal sprouting and synaptogenesis in the rat

spinal cord produced by antibodies to nerve growth factor. Eighth Annual Meeting of the International Society for Developmental Neuroscience, Abstr. 1(8): 92, 1990.

41. Hulsebosch, C.E., W.T. Stamps, T.E. Kruger and B.A. Urschel. Effects of peripheral

injury on the distribution of nerve growth factor receptor (NGFR) and NGFR mRNA in the spinal cord and brain. Neurosci. Abstr. 16(1): 297, 1990.

42. Urschel, B.A. and Hulsebosch, C.E. Distribution of nerve growth factor receptors

(NGFR) in the rat spinal cord as a function of age and NGF suppression. Neurosci. Abstr. 16(2): 987, 1990.

43. Hulsebosch, C.E., Ruda, M.A., Dubner, R. and Willis, W.D. Plasticity in pain pathways.

Winter Conference on Brain Research, 1991. 44. Urschel, B.A. and C.E. Hulsebosch. Distribution and relative density of nerve growth

factor receptors (NGRF) in the rat brain as a function of age and anti-NGF treatment. Neurosci. Abstr. 1991.

45. C.E. Hulsebosch, P.N. Brown, and B.A. Urschel. Differential effects on sensory nerve

processes and behavioral alterations in the rat after treatment with anti-NGF. Neurosci. Abstr. 1991.

46. R.P. Stroemer, T.A. Kent and C.E. Hulsebosch. Changes in synaptophysin levels

following ischemic insult. Neurosci. Abstr. 17: 1082, 1991. 47. R.H. Fabian and C.E. Hulsebosch. 7S-NGF penetrates from the blood to the CNS in the


neonatal rat. Neurosci. Abstr. 1991. 48. Morgan, B., Hulsebosch, C.E., Eisenberg, H.M., Pizzo, D.P., Westlund, K.N., Lu, Y., and

Kutyna, M. Development of Genetically Modified Cells for Brain Transplants. American Association of Neurological Surgeons, 1992.

49. Pizzo, D.P., Hutton, L., Westlund, K.N., Lu, Y, Werrbach-Perez, K., Morgan, B.,

Hulsebosch, C.E., Eisenberg, H. and Perez-Polo, R. Characteristics of HCN-1A Cells: Potential Transplant use. Twenty-Third Annual Meeting American Society for Neuro-Chemistry, 1992.

50. Hulsebosch, C.E., Brown, P.N. and Urschel, B.A. Differential effects on sensory nerve

processes and behavioral alterations in the rat after treatment with anti-NGF. American Pain Society, Abstr. 1992.

51. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Increases in Gap 43 immunoreactivity

after cortical infarction. Neurosci. Abstr. 18: 1260, 1992. 52. Song, Y., Simard, J.M., Werrbach-Perez, K., Eisenberg, H.M., Perez-Polo, R.,

Westlund, K.N. and Hulsebosch, C.E. Ion channel currents in cultured HCN-1A neurons from human cortex. Neurosci. Abstr. 18: 1260, 1992.

53. Hulsebosch, C.E. and Dorman, J. Strategies in transplant therapy for spinal cord injury.

Neurosci. Abstr. 1992. 54. Morgan, B., Pizzo, D., Werrbach-Perez, K., Hutton, L., Lu, Y., Westlund, K.M.,

Hulsebosch, C.E., Eisenberg, H.M. and Perez-Polo, R. Transplantation of HCN-1A into rat brain. Neurosci. Abstr. 1992.

55. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Sprouting and synaptogenesis

following cortical infarction. 18th International Joint Conference on Stroke and Cerebral Circulation, Stroke 24: 162, 1993.

56. Hulsebosch, C.E., Urschel, B.A. and Carlton, S.M. Postnatal development of

nociceptors requires nerve growth factor. 7th World Congress on Pain, Paris, France, 1993.

57. Hulsebosch, C.E., Pizzo, D.P. and Zompa, E.A. Migration and differentiation of PC12

cells transplanted into the rat spinal cord. Neurosci. Abstr. 1993. 58. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Amphetamines promote anatomical

plasticity and behavioral recovery following cortical infarction. Neurosci. Abstr. 1993. 59. Fabian, R.H., Welch, A.L., Chen, Y.C. and Hulsebosch, C.E. Maternal antibodies access

the neonatal central nervous system. Neurosci. Abstr. 1993. 60. Lu, Y., Westlund, K.N., Hulsebosch, C.E., Harmann, P.A., Pizzo, D.P., Terrell, M.L.,

Kadekaro, M., Eisenberg, H.M. and Perez-Polo, R. Transplantation of fibroblasts transfected with nerve growth factor gene in rats with nigral lesions. Neurosci. Abstr.


1993. 61. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Cortical plasticity following stroke,

Neurotrauma Society, Eleventh Annual Neurotrauma Symposium, 1993. 62. Michaud, M., Riccardi, V.M. and Hulsebosch, C.E. Dysfunctional neurite growth and

nerve growth factor involvement in NF-1 Neurofibromatosis. Neurosci. Abstr. 1994. 63. Stroemer, R.P., Kent, T.A., and Hulsebosch, C.E. Amphetamines permanently

promote recovery following cortical infarction. Neurosci. Abstr. 1994. 64. Christensen, M.D., and Hulsebosch, C.E. Distribution of Gap-43 expression in the

spinal cord following low thoracic hemisection. Neurosci. Abstr. 1994. 65. Hulsebosch, C., Fabian, R., Jenkins, L., and Prough, D. Fluid-percussion injury results

in increased brain penetrability of -NGF. J. Neurotrauma 12: 123, 1995. 66. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Correlation of cortical plasticity with

behavioral recovery following stroke with amphetamine administration. Satellite Symp. Brain 95. XVI Int. Symp. Cerebral Blood Flow and Metabolism, 1995.

67. Christensen, M.D., Pickelman, J., Ziainia, M. and Hulsebosch, C.E. Mechanical

allodynia and thermal hyperalgesia in chronic central pain following spinal cord injury. Neurosci. Abstr. 1995.

68. Zompa, E.A., Moyer, M.P., Cain, L. and Hulsebosch, C.E. Phenotypic characterization

of normal human fetal spinal cord cells in culture. Neurotrauma Society, 1995. 69. Hulsebosch, C.E., Christensen, M.D., Peng, Y.B. and Willis, W.D. Central sensitization

in chronic central pain after spinal cord hemisection. Neurosci. Abstr. 1995. 70. Quast, M., Kent, T., Taglialatela, G., Huang, N., Pizzo, D., Hulsebosch, C., Rassin, D.

and Perez-Polo, R. Effects of ischemia on neurotrophin and GSH. Neurosci. Abstr. 1995. 71. Hulsebosch, C.E., Jenkins, L., DeWitt, D. and Prough, D. Fluid-percussion injury results

in increased expression of GAP-43. J. Neurotrauma 12: 989, 1995. 72. Zompa, E.A., Pizzo, D.P., Perez-Polo, R. and Hulsebosch, C.E. Transplantation of PC12

cells into the rat spinal cord. Neurotrauma Society, 1995. 73. Hulsebosch, C.E., Christensen, M.D., Peng, Y.B. and Willis, W.D. Central sensitization

of wide dynamic range neurons in chronic central pain after spinal cord hemisection. Am. Pain Soc. 21: 1761, 1995.

74. Christensen, M.D., Pickelman, J., Zianinia, M. and Hulsebosch, C.E. Temporal

development of mechanical allodynia and thermal hyperalgesia in chronic central pain following spinal cord injury. Am. Pain Soc., 1995.

75. Bennett, A.D., Christensen, M.D. and Hulsebosch, C.E. Effects of AP-5 and NBQX on


chronic central pain following spinal cord hemisection. Am. Pain Soc., 1995. 76. Hulsebosch, C.E., Murray, M., Fischer, I. and Wilcox, G.L. Cellular and molecular

interventions toward improved function after spinal cord injury. Winter Conference on Brain Research, 1996.

77. Hulsebosch, C.E. Cellular and molecular mechanisms in spinal cord injury transplants

and growth factors: Toward recovery of function. 14th Ann. Houston Conf. on Biomed. Engr. Res., 123, 1996.

78. Hulsebosch, C.E., DeWitt, D.S., Jenkins, L.W. and Prough, D.S. Moderate traumatic

brain injury (TBI) and delayed secondary focal ischemia increases remote neuronal death. Am. Soc. Anesthesiol., 1996.

79. Bennett, A.D., Christensen, M.D. and Hulsebosch, C.E. Dose response effects of AP-5

and NBQX on chronic central pain following spinal cord hemisection. Neurosci. Abstr., 1996.

80. Zompa, E.A., Moyer, M.P., Cain, L. and Hulsebosch, C.E. Long term culture and

characterization of normal human fetal spinal cord cells. Neurocsi. Abstr., 1996. 81. Christensen, M.D., Everhart, A. and Hulsebosch, C.E. Anti-NGF prevents thermal

allodynia in chronic central pain following spinal cord injury. Neurosci. Abstr., 1996. 82. Hulsebosch, C.E. and Christensen, M.D. Changes in distribution of CGRP peptide

following spinal cord hemisection provide a mechanism for chronic central pain states. Neurosci. Abstr., 1996.

83. Hulsebosch, C.E., DeWitt, D.S., Jenkins, L.W. and Prough, D.S. Remote neuronal death

is not due to ischemia after moderate traumatic brain injury (TBI) and delayed secondary focal ischemia. Neurotrauma Soc., 1996.

84. Zompa, E.A., Moyer, M.P., Cain, L., Morshed, T. and Hulsebosch, C.E. Transplantation

of human fetal spinal cord cells induces robust neurite sprouting. Neurotrauma Soc., 1996.

85. Christensen, M.D., Supowit, S.C., DiPette, D.J. and Hulsebosch, C.E. Enhanced gene

expression of CGRP and GAP-43 in dorsal root ganglia by spinal hemisection and nerve growth factor. Neurotrauma Soc. 13: 603, 1996.

86. Kent, T., Taglialatela, G., Rassin, D., Quast, M., Wei, G., Rea, C., Hulsebosch, C.,

Werrbach-Perez, K. and Perez-Polo, R. Oxidative stress and ischemia. Neurotrauma Soc., 1996.

87. Hulsebosch, C.E., Everhart, A.W., Moyer, M.P., Cain, L.D. and Zompa, E.A. Behavioral

assessment after spinal transplantation of human fetal spinal cord cells in non-immunosuppressed rats. Neurosci. Abstr., 1997.

88. Zompa, E.A., Cain, L.D., Moyer, M.P. and Hulsebosch, C.E. Spinal transplantation of


human fetal spinal cord cells in non-immunosuppressed rats. Neurosci. Abstr., 1997. 89. Christensen, M.D., Supowit, S.C., DiPette, D.J. and Hulsebosch, C.E. A study of

upregulation of gene expression by spinal hemisection and nerve growth factor. Neurosci. Abstr., 1997.

90. Everhart, A.W., Willis, W.D. and Hulsebosch, C.E. Gabapentin inhibits mechanical and

thermal allodynia in a rodent model of chronic central pain following spinal hemisection. Neurosci. Abstr., 1997.

91. Bennett, A.D., Everhart, A.W. and Hulsebosch, C.E. Effects of CGRP8-37 on mechanical

and thermal allodynia in rodent model of chronic central pain following spinal hemisection. Neurosci. Abstr., 1997.

92. Hulsebosch, C.E., Everhart, A.W., Moyer, M.P., Cain, L.D. and Zompa, E.A. Spinal

transplantation of human fetal spinal cord cells in non-immunosuppressed rats accelerates behavioral recovery. Natl. Neurotrauma Soc., 1997.

93. Everhart, A.W., Willis, W.D. and Hulsebosch, C.E. GABApentin inhibits mechanical and

thermal allodynia without compromising locomotion in a rodent model of chronic central pain following spinal hemisection. Natl. Neurotrauma Soc., 1997.

94. de Castro Jr., R., Xu, G-Y., Hulsebosch, C.E., Everhart, A.W. and McAdoo, D.J.

Neutrophil ablation decreases protein oxidation and improves behavioral outcome upon spinal cord injury. Natl. Neurotrauma Soc., 1997.

95. Christensen, M.D. and Hulsebosch, C.E. Nerve growth factor antibodies inhibit the

development and thermal allodynia in chronic central pain following spinal cord injury. The American Assoc. of Neurological Surgeons, 1997.

96. Christensen, M.D., Supowit, S., DiPette, D. and Hulsebosch, C.E. Gene expression of

CGRP and GAP-43 in dorsal root ganglia following psinal hemisection and nerve growth factor. The American Assoc. of Neurological Surgeons, 1997.

97. Moyer, M.P., Zompa, E.A., Johnson, R.A. and Hulsebosch, C.E. Human fetal spinal cord

neural progenitor cell lines: Pre-clinical validation for transplantation. Williamsburg Bioprocessing Foundation, 1997.

98. Bennett, A.D., Taglialatela, G., Perez-Polo, J.R. and Hulsebosch, C.E. Changes in spinal

cord and DRG NGF content after spinal hemisection in rats. Neurosci. Abstr. 24: 1287, 1998.

99. Hains, B.C., Chastain, K.M., Everhart, A.W. and Hulsebosch, C.E. Reduction of chronic

central pain following spinal cord injury by transplants of adrenal medullary chromaffin cells. Neurosci. Abstr. 24: 1631, 1998.

100. Hulsebosch, C.E., Chastain, K.M. and Everhart, A.W. Age related development of

chronic central pain in a spinal cord injury model. Neurosci. Abstr. 24: 1393, 1998.


101. Hains, B.C., Chastain, K.M., Everhart, A.W. and Hulsebosch, C.E. Adrenal medullary chromaffin cell transplants reduce chronic pain following spinal cord injury. Natl. Neurotrauma Soc., 1998.

102. Hulsebosch, C.E., Ye, Z., Xu, G-Y., Westllund, K.N., Mcadoo, D.J., Taglialatela, G. and

Perez-Polo, J.R. NF-κB expression after spinal cord injury in the rat. Natl. Neurotrauma Soc., 1998.

103. Bennett, A.D., Everhart, A.W. and Hulsebosch, C.E. Dose dependent effects of

CGRP(8-37) on mechanical and thermal allodynia in a rodent model of chronic central pain following spinal hemisection. APS Abstr., 1998.

104. Hulsebosch, C.E., Woolf, C., Ruda, M.A. and Willis, W.D. The protean nature of pain.

Winter Conference on Brain Research, 1998. 105. Hulsebosch, C.E., Everhart, A., Bennett, A. and Willis, W.D. Behavioral

electrophysiological and pharmacological characterization of a rodent model of chronic central pain after spinal cord injury. J. Spinal Cord Med. 21: 356, 1998.

106. Bennett, A., Chastain, K. and Hulsebosch, C.E. Dose dependent alleviation of

mechanical and thermal allodynia with CGRP8-37 following spinal hemisection in rats. 9th World Congress on Pain, Vienna, Austria, 1999.

107. Hains, B.C., Chastain, K.M., Everhart, A.W. and Hulsebosch, C.E. Cellular

transplantation for delivery of catecholamines as treatment for chronic central pain after spinal cord injury. 9th World Congress on Pain, Vienna, Austria, 1999.

108. Hulsebosch,C.E., Taylor, C.P., Everhart, A. and Gonzalez, F.P. Spontaneous

measures of chronic central pain after spinal cord injury alleviated by gabapentin. 9th World Congress on Pain, Vienna, Austria, 1999.

109. Hulsebosch, C.E., Xu, G-Y., Perez-Polo, J.R., Westlund, K.N. and McAdoo, D.J.

Development of chronic central pain in a SCI contusion model. Neurosci. Abstr. 25: 1329, 1999.

110. Vera-Portocarrero, L., Ye, Z., Xu, G.Y., Hulsebosch, C.E., McAdoo, D.J. and Westlund,

K.N. Glutamate transporters increase in a model of spinal cord injury. Neurosci. Abstr. 25: 428, 1999.

111. Mills, C.D., Chastain, K.M. and Hulsebosch, C.E. Quantification of spontaneous activity

following spinal cord injury in rat. Neurosci. Abstr. 25: 1328, 1999. 112. Hains, B.C., Chastain, K.M. and Hulsebosch, C.E. Distribution of spinal serotonin

transporter, and receptor subtypes following acute and chronic hemisection injury in the rat. Neurosci. Abstr. 25: 922, 1999.

113. Bennett, A.D., Wimalawansa, S.J. and Hulsebosch, C.E. Changes in the expression of

calcitonin gene-related peptide and its receptor in the lumbar and cervical spinal cord after spinal hemisection. Neurosci. Abstr. 25: 2219, 1999.


114. Perez-Polo, J.R., Qiu, J., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C. Alteration of bcl-

xL levels in rat spinal cord after a contusion injury. Neurosci. Abstr. 25: 1773, 1999. 115. Perez-Polo, J.R., Qiu, J., Xu, G-Y., Mcadoo, D.J. and Hulsebosch, C.E. Expression of

anti-apoptotic protein bcl-xL in rat spinal cord after contusion injury. Natl. Neurotrauma Soc., 1999.

116. Hulsebosch, C.E., Xu, G-Y., Perez-Polo, J.R., Westlund, K.N. and McAdoo, D.J. A

rodent model of chronic central pain after spinal contusion injury. Natl. Neurotrauma Soc., 1999.

117. Hains, B.C., Chastain, K.M. and Hulsebosch, C.E. Traumatic spinal hemisection injury

results in alterations of 5-HT, 5-HTT, and 5-HT receptor subtypes 1A, 1B, and 2A distribution. Natl. Neurotrauma Soc., 1999.

118. Vera-Portocarrero Ye, Z., Xu, G-Y., Hulsebosch, C.E., McAdoo, D.J. and Westlund,

K.N. Spinal contusion injury induces changes in immunodensity of neuronal and glial glutamate transporters. Natl. Neurotrauma Soc., 1999.

119. Hulsebosch, C.E., Taylor, C.P., Everhart, A. and Gonzalez, F.P. Gabapentin alleviates

spontaneous measures of chronic central pain after spinal cord injury. Neurosci. Abstr. 26: 1216, 2000.

120. McAdoo, D.J., Mills, C.D. and Hulsebosch, C.E. Changes in metabotropic glutamate

receptor expression following spinal cord injury in rat. Neurosci. Abstr. 26: 1651, 2000. 121. Hains, B.C., Johnson, K.A., Eaton, M.J. and Hulsebosch, C.E. Transplantation of

immortalized serotonergic neurons attenuates chronic central pain after spinal hemisection injury in rat. Neurosci. Abstr. 26: 2303, 2000.

122. Ye, Z., Hulsebosch, C., McAdoo, D., Xu, G. and Westlund, K.N. Long term changes in

the expression and activity of NMDA glutamate receptors in the spinal cord after contusion spinal cord injury. Neurosci. Abstr. 26: 1647, 2000

123. Bennett, A.D., Hains, B.C., Yucra, J.A. and Hulsebosch, C.E. Reduction of pathological

and behavioral deficits after spinal cord contusion injury with the selective COX-2 inhibitor NS-398. Neurosci. Abstr. 26: , 2000.

124. Mills, C.D., Xu, G.Y., McAdoo, D.J. and Hulsebosch, C.E. Administration of aida

reduces extracellular glutamate following spinal cord injury in rat. Neurosci. Abstr. 26: 1135, 2000.

125. Mills, C.D., Xu, G.Y., McAdoo, D.J. and Hulsebosch, C.E. AIDA decreases extracellular

glutamate concentrations after spinal cord injury. Natl. Neurotrauma Soc., 2000. 126. Hains, B.C., Yucra, J.A. and Hulsebosch, C.E. Selective COX-2 inhibition preserves

spinal parenchyma and attenuates behavioral deficits following spinal contusion injury. Natl. Neurotrauma Soc., 2000.


127. Ye, Z., Hulsebosch, C., McAdoo, D., Xu, G. and Westlund, K.N. Long-term differential

expression of NR1 and phosphorylated NR1 subunits of NMDA receptors in a contusion spinal cord injury. Natl. Neurotrauma Soc., 2000.

128. Hulsebosch, C.E., Taylor, C.P., Everhart, A. and Gonzalez, F.P. Spontaneous

measures of chronic central pain after spinal cord injury. Natl. Neurotrauma Soc., 2000. 129. Hains, B.C., Yucra, J.A. and Hulsebosch, C.E. Selective COX-2 inhibition preserves

spinal parenchyma and attenuates behavioral deficits following spinal contusion injury. Natl. Neurotrauma Soc., 2000.

130. Nesic, O., McAdoo, D., Xu, G-Y., Hulsebosch, C., Rea, H., Dalmeida, W., Opp, M. and

Perez-Polo, R. The role of cytokines in spinal cord injury. Neurosci. Abstr. 26: 510, 2000. 131. Fullwood, S.D., Xu, G-Y., Hulsebosch, C.E. and McAdoo, D.J. Multiple actions of NBQX

post-spinal cord injury. Neurosci. Abstr., 2001 132. Ye, Z., Fullwood, S., Hulsebosch, C., McAdoo, D., Xu, G-Y. and Westlund, K.N.

Upregulation of NR1 and phosphorylated NR1 NMDA receptor subunits rostral to contusion injury in rat. Neurosci. Abstr., 2001.

133. Mills, C.D., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C.E. Group 1 metabotropic

glutamate receptors in excitotoxic events following spinal cord injury in rat. Neurosci. Abstr., 2001

134. Hains, B.C., Bennett, A.D., Eaton, M.J. and Hulsebosch, C.E. Intralesion

transplantation of serotonin- and BDNF-secreting cells promotes recovery of locomotor function after spinal hemisection injury. Neurosci. Abstr., 2001.

135. Hulsebosch, C.E., Mills, C.D., Hains, B.C. and Johnson, K.M. Strain and model

differences in behavioral outcomes following spinal cord injury in rat. Neurosci. Abstr., 2001.

136. Hains, B.C., Eaton, M.J., Willis, W.D. and Hulsebosch, C.E. Engraftment of

conditionally immortalized serotonergic neurons amends hyperexcitability of dorsal horn neurons after spinal hemisection-induced central sensitization. Neurosci. Abstr., 2001.

137. Hains, B.C., Johnson, K.M., Fullwood, S.D., Eaton, M.J. and Hulsebosch, C.E. Lumbar

engraftment of RN46A cells corrects abnormal spinal 5-HT and 5-HTT, increases tissue BDNF, and attenuates behavioral dysfunction after spinal hemisection injury in rat. Am. Soc. Neural Transplantation & Repair 8th Annual Conf., 2001.

138. Mills, C.D., McAdoo, D.J. and Hulsebosch, C.E. Roles of metabotropic glutamate

receptors in spinal cord injury. J. Neurotrauma 18: 1182, 2001. 139. Hulsebosch, C.E., Mills, C.D., Hains, B.C. and Johnson, K.M. Genetic and model

differences in behavioral outcomes following spinal cord injury in rat. J. Neurotrauma 18: 1125, 2001.


140. Hains, B.C., Eaton, M.J., Willis, W.D. and Hulsebosch, C.E. 5-HT/BDNF cell therapy for

chronic pain after spinal injury in rat: Anatomical behavioral and electrophysiological characterization. J. Neurotrauma 18: 1152, 2001.

141. Nesic, O., Svrakic, N., Xu, G-Y., McAdoo, D., Westlund, K., Hulsebosch, C., Galante,

A., Soteropoulos, P., Tolias, P., Young, W., Hart, R.P. and Perez-Polo, R. DNA array analysis of MK-801 effect on spinal cord injury. J. Neurotrauma 18: 1139, 2001.

142. Nesic, O., Svrakic, N.M., Xu, G-Y., McAdoo, D., Westlund, K.N., Hulsebosch, C.E. and

Perez-Polo, R.J. Interleukin 1 receptor antagonist – treatment of spinal cord injury (SCI). 3rd Deauville Int. Conf. On Spinal Cord Injury, Normandy, France, Apr. 10-12, 2002.

143. Tan, H., Johnson, K.M., Neugebauer, V., Willis, W.D. and Hulsebosch, C.E. Dorsal horn

activity and NMDA receptor contributions after spinal cord injury in rat. Neurosci. Abstr., 2002.

144. Gwak, Y.S., Hains, B.C., Johnson, K.M. and Hulsebosch, C.E. Effect of age at time of

spinal cord injury on behavioral outcomes in rat. Neurosci. Abstr., 2002. 145. Hulsebosch, C.E.,Hains, B.C. and Willis, W.D. Acute spinal hemisection produces

bilateral hyperexcitability of dorsal horn neurons. Neurosci. Abstr., 2002. 146. Fullwood, S.D., Johnson, K.M., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C.E. AMPA

receptors contribute to chronic central pain (CCP) after spinal cord injury (SCI). Neurosci. Abstr., 2002.

147. Lemoine, Y.E., Bennett, A.D., Nie, L., Hulsebosch, C.E. and McAdoo, D.J. Temporal

changes in LIF expression after spinal cord injury (SCI). Neurosci. Abstr., 2002. 148. Johnson, K.M., Hains, B.C., McAdoo, D.J. and Hulsebosch, C.E. Exogenous leukemia

inhibitory factor (LIF) attenuates the development of mechanical and thermal allodynia after spinal cord injury (SCI). Neurosci. Abstr., 2002.

149. Ye, Z., Hulsebosch, C., McAdoo, D., Xu, G-Y. and Westlund, K.N.. Phospho-NR1

NMDA receptor subunit increases in white matter oligodendrocytes in contused rat spinal cord. Neurosci. Abstr., 2002.

150. Nesic, O., Xu, G-Y., Johnson, K.M., McConnel, R.I., McAdoo, D.J., Hulsebosch, C.E.

and Perez-Polo, J.R. Gene expression changes underlying chronic central pain in rat model of contusion spinal cord injury (SCI). Neurosci. Abstr., 2002.

151. Johnson, K.N., Hains, B.C., McAdoo, D.J. and Hulsebosch, C.E. Chronic central pain

is attenuated exogenous leukemia inhibitory factor (LIF) after spinal cord injury (SCI). Natl. Neurotrauma Soc., 2002.

152. Fullwood, S.D., Johnson, K.M., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C.E. AMPA

receptors affect the development of chronic central pain (CCP) after spinal cord injury (SCI). Natl. Neurotrauma Soc., 2002.


153. Gwak, Y.S., Hains, B.C., Johnson, K.M. and Hulsebosch, C.E. Age-dependency on

development of neuropathic pain behavior following spinal cord injury in rat. Natl. Neurotrauma Soc., 2002.

154. Hulsebosch, C.E., Hains, B.C. and Willis, W.D. Bilateral hyperexcitability of lumbar

dorsal horn neurons following unilateral thoracic hemisection-basis for “phantom” neuropathic pain. Natl. Neurotrauma Soc., 2002.

155. Nesic, O., Svrakic, N.M., Xu, G-Y., McAdoo, D., Westlund, K.N., Hulsebosch, C.E. and

Perez-Polo, R.J. Interleukin 1 dependent cell loss after spinal cord injury (SCI). Int. Soc. Neurochem., J. Neurochem. 81 (Suppl. 1) 107, 2002.

156. Gwak, Y.S., Johnson, K.M. and Hulsebosch, C.E. Activation of group I metabotropic

glutamate receptors enhances nociceptive input following spinal hemisection in rats. Neurosci. Abstr., 2003.

157. Ye, Z., Hulsebosch, C.E., McAdoo, D.J., Xu, G. and Westlund, K.N. Increased

expression of the NMDA glutamate receptor subunit NR1 in spinothalamic tract neurons one month after spinal cord contusion injury. Neurosci. Abstr., 2003.

158. Hulsebosch, C.E., Yang, J., Grill, R., Davies, S.J., Deyo, D.J., Unabia, G.C., Johnson,

L.K. and Clifton, G.L. Sheep – A large mammalian model for translational research in central and peripheral nervous system injury. Neurosci. Abstr., 2003.

159. Tan, H., Johnson, K.M. and Hulsebosch, C.E. Dorsal horn activity and ionotropic

glutamate receptor contributions after spinal cord injury in rat. Neurosci. Abstr., 2003. 160. Fullwood, S.D., Unabia, G.C., Johnson, K.M., McAdoo, D.J. and Hulsebosch, C.E.

Distribution of AMPA receptor subunits following spinal cord injury (SCI). Neurosci. Abstr., 2003.

161. Carter, M.W., Fullwood, S.D., McAdoo, D.J. and Hulsebosch, C.E. The effects of

leukemia inhibitory factor on inflammation in spinal cord injury. Neurosci. Abstr., 2003. 162. Hughes, M.G., Nie, L., Xu, G-Y., Shah, B., Hulsebosch, C. and McAdoo, D.J.

Assessment of mechanisms of glutamate elevation following spinal cord injury. Neurosci. Abstr.., 2003.

163. Xu, G., Hughes, M.G., Ye, Z., Hulsebosch, C.E. and McAdoo, D.J. Glutamate released

following spinal cord injury kills oligodendrocytes in the spinal cord. Neurosci. Abstr., 2003.

164. Fullwood, S.D., Unabia, G.C., Johnson, K.M., McAdoo, D.J. and Hulsebosch, C.E.

Spinal cord injury (SCI) alters AMPA receptor subunit distribution. Natl. Neurotrauma Soc., 2003.

165. Carter, M.W., Fullwood, S.D., McAdoo, D.J. and Hulsebosch, C.E. Inflammation

response in spinal cord injury: The effects of leukemia inhibitory factor. Natl.


Neurotrauma Soc., 2003. 166. Hulsebosch, C.E., Yang, J.P., Grill, R.J., Davies, S.J., Deyo, D.J., Unabia, G.C., Ye, Z.,

Rooney, B.A., Johnson, K.M. and Clifton, G.L. Sheep: A large mammalian model for translational research in neurotrauma. Natl. Neurotrauma Soc., 2003.

167. Gwak, Y.S., Johnson, K.M. and Hulsebosch, C.E. Altered expression of metabotropic

glutamate receptors in the dorsal horn following spinal hemisection in rats. Natl. Neurotrauma Soc., 2003.

168. Ye. Z., Hulsebosch, C.E., McAdoo, D.J. and Westlund, K.N. Spinal cord contusion injury

induces upregulation of the NMDA glutamate receptor subunit NR1 in spinothalamic tract neurons. Natl. Neurotrauma Soc., 2003.

169. Gwak, Y.S. and Hulsebosch, C.E. Inhibition of astrocytic activation prevents induction

and maintenance of central neuropathic pain following spinal cord injury in rat. Natl. Neurotrauma Soc., 2004.

170. Gwak, Y.S. and Hulsebosch, C.E. Expression of metabotropic glutamate receptors in

neurons and astrocytes in the spinal dorsal horn following spinal cord injury. Neurosci. Abstr., 2004.

171. Crown, E.D. and Hulsebosch, C.E. Central neuropathic pain: A form of maladaptive

molecular memory. Neurosci. Abstr., 2004. 172. Crown, E.D. and Hulsebosch, C.E. Spinal cord injury activates intraspinal signaling

cascades associated with long-term potentiation and central sensitization. Natl. Neurotrauma Soc., 2004.

173. Rooney, B.A., Hulsebosch, C.E. and McAdoo, D.J. A rat model failed back surgery

syndrome: Insights into etiology. Natl. Neurotrauma Soc., 2004. 174. Rooney, B.A., Hulsebosch, C.E. and McAdoo, D.J. Injury induced increases in

extracellular excitatory amino acid concentrations in the rat spinal cord: A model of failed back surgery syndrome. Neurosci. Abstr., 2004.

175. Johnson, K.M., Ye, Z., Crown, E., Xu, G-Y., McAdoo, D.J., Westlund, K.N. and

Hulsebosch, C.E. Spinal cord contusion injury induces upregulation of calcium-calmodulin-dependent protein kinase II spinothalamic tract neurons. Natl. Neurotrauma Soc., 2004.

176. Carter, M.W., Tan, H-Y., Johnson, K.M. and Hulsebosch, C.E. Effects of force and

dwell-time in modeling chronic central neuropathic pain after contusive spinal cord injury (SCI). Neurosci. Soc., 2004.

177. Carter, M.W., Tan, H-Y., Johnson, K.M. and Hulsebosch, C.E. Modeling chronic central

neuropathic pain using adjustments in force and dwell-time in contusive spinal cord injury (SCI). Natl. Neurotrauma Soc., 2004.


178. Tarasenko, Y.I., Nie, L., McAdoo, D.J., Johnson, K.M., Hulsebosch, C.E., Grady, J.J. and Wu, P. Primed human neural stem cells grafted into contusion injured spinal cord of a rat. Neurosci. Abstr., 2004.

179. Tan, H., Johnson, K.M. and Hulsebosch, C.E. Role of ionotropic glutamate receptors in

a rodent model of central neuropathic pain. Neurosci. Abstr., 2004. 180. Ye, Z., Crown, E., Xu, G., McAdoo, D.J., High, K.W. and Hulsebosch, C.E. Increased

expression of calcium-calmodulin-dependent protein kinase II in spinothalamic tract neurons one hour after spinal cord contusion injury. Neurosci. Abstr., 2004.

181. Gwak, Y.S. and Hulsebosch, C.E. Astrocytic activation contributes to induction and

maintenance of central neuropathic pain after spinal cord injury in rodent model. 11th World Congress on Pain, Sydney, Australia, Aug. 2005.

182. Gwak, Y.S., Crown, E., Hulsebosch, C.E. Spinal cord injury produces chronic

astrocytic activation downregulation of glutamic acid decarboxylase decreased GABAergic inhibitory tone central neuropathic pain. Natl. Neurotrauma Soc., 2005.

183. Gwak, Y.S., Hulsebosch, C.E. Upregulation of group I metabotropic glutamate receptors in neurons and astrocytes in the dorsal horn following spinal cord injury. Neurosci. Soc., 2005.

184. Cittelly, D.M., Nesic, O., Hulsebosch, C.E. and Perez-Polo, J.R. Subcellular

distribution of bcl-xL in injured spinal cord. Neurosci. Soc. 2005. 185. Carlton, S.M., Du, J., Hulsebosch, C.E. Peripheral sensitization contributes to central neuropathic pain ion spinal cord injured rats. Neurosci. Soc., 2005. 185. Bopp, A., Hargett, G., Hulsebosch, C.E., Carlton, S.M. Contributions of ischemia

and tissue reperfusion to pressure ulcer severity. Natl. Neurotrauma Soc., 2005. 186. Crown, E.D., Ye, Z., Xu, G-Y., Johnson, K.M., McAdoo, D.J., Hulsebosch, C.E.

Mechanisms of central neuropathic pain following spinal cord injury: Role of the transcription factor CREB. Neurosci. Soc., 2005.

187. Ye, Z. et al. Increase in the phosphorylation of mitogen-activated protein (MAP)

kinases (p- ERK, p-JNK, and p-P38) in spinal cord glial cells one month after spinal cord. Natl. Neurotrauma Soc., 2005.

188. Ye, Z. et al. Increase in the phosphorylation of mitogen-activated protein (MAP)

kinases (p- ERK, p-JNK, and p-P38) in spinal cord glial cells one month after spinal cord. Neurosci. Soc., 2005.

189. Crown, E.D. et al. Role of the transcription factor CREB in chronic central

neuropathic pain following spinal cord injury. Natl. Neurotrauma Soc., 2005. 190. Carter, M.W., Johnson, K.M., Unabia, G.C., Hulsebosch, C.E. Therapeutic

targeting of neutrophils in contusive SCI reduces secondary injury and improves


outcomes. Neurosci. Soc., 2005. 191. Cain, L.D. et al. Albumin promotes the functional recovery of rats after spinal cord

contusion injury. Natl. Neurotrauma Soc., 2005. 192. Rooney, B.A., Hulsebosch, C.E. Functional changes to the micturition reflex in a model

of cauda equine injury. Natl. Neurotrauma Soc., 2005. 193. Rooney, B.A., Hulsebosch, C.E. Model of cauda equine injury: Effects on bladder

detrusor and external urethral sphincter coordination. Neurosci. Soc., 2005. 194. Tan, Y-Y., Johnson, K.M., Hulsebosch, C.E. Electrophysiological characterization

of a rodent contusion model of central neuropathic pain after spinal cord injury. Neurosci. Soc., 2005.

195. Johnson, K.M., Tan, H. and Hulsebosch, C.E. Role of ionototropic glutamate

receptors in a rodent model of central neuropathic pain after spinal cord injury. Neurosci. Soc., 2005.

197. Hulsebosch, C.E., Gwak, Y.S., Johnson, K.M., Ye, Z., Unabia, G.C., Xu, G-Y., Perez-

Polo, J.R., Nesic, O. and McAdoo, D.J. IL-1 receptor antagonist attenuates mechanical allodynia and decreases glial activation and IL-1 beta production after spinal cord injury (SCI). Neurosci. Soc., 2006.

198. Carter, M.W., Johnson, K.M., Unabia, G.C. and Hulsebosch, C.E. Recombinant

neutrophil inhibitory factor (rNIF) in the early treatment of spinal cord injury (SCI): behavioral, histological and biochemical outcomes. Neurosci. Soc., 2006.

199. Gwak, Y., Crown, E.D. and Hulsebosch, C.E. Astrocytic control of gabaergic inhibition

in mechanical allodynia by downregulation of glutamic acid decarboxylase65 following spinal cord injury. Neurosci. Soc., 2006.

200. Du, J., Lin, Q., Hulsebosch, C.E., Willis, W.D. and Carlton, S.M. Spinal cord injury pain:

contributions from sensitized afferents and dorsal root reflexes. Neurosci. Soc., 2006. 201. Crown, E.D., Ye, Z., Tan, H., Johnson, K.M., Xu, G., McAdoo, D.J., Hulsebosch, C.E. Calcium/calmodulin-dependent kinase II plays a critical role in at-level mechanical

allodynia after spinal cord injury in rats. Neurosci. Soc., 2006. 202. Rooney, B.A., Hulsebosch, C.E., McAdoo, D.J. Preemptive analgesia with lidocaine

prevents failed back surgery syndrome. Neurosci. Soc., 2006. 203. Ye, Z., Crown, E., Unabia, G., Johnson, K., Nesic, O., Xu, G., McAdoo, D.J. and

Hulsebosch, C.E. Increased phosphorylation of mitogen-activated protein (map) kinase p-p38 in spinal cord neurons and microglia but not astrocytes after spinal cord contusion injury. Neurosci. Soc., 2006.

204. Bopp-Crown, A.C., Hargett, G.L., Hulsebosch, C.E., Shapiro, G. and Carlton, S.M.

Systemic treatment with SCR007, a somatostatin receptor 2 agonist, attenuates at-level


pain after spinal cord contusion injury. Neurosci. Soc., 2006. 205. Liu, S., Johnson, K.M., Xu, G., Hulsebosch, C.E. and McAdoo, D.J. The reciprocity of

IL-1β and IL-1ra in glutamate induced spinal cord injury. Neurosci. Abstr., 2006. 206. Gwak, Y.S., Unabia, G. and Hulsebosch, C.E. Inhibition of neuronal p-38 MAPK

activation attenuates below-level central neuropathic pain following spinal cord injury. Natl. Neurotrauma Soc., 2007.

207. Gwak, Y., Unabia, G. and Hulsebosch, C.E. Activation of neuronal, not glial, p-38

MAPK maintains hyperexcitability of dorsal horn neurons at caudal region following spinal cord injury in rat. Neurosci. Abstr., 2007.

208. Crown, E.D., Gwak, Y.S., Ye, Z., Johnson, K.M. and Hulsebosch, C.E. Activation

of p38 MAP kinase is involved in central neuropathic pain following spinal cord injury. Natl. Neurotrauma Soc., 2007.

209. Crown, E.D., Gwak, Y.S., Ye, Z., Johnson, K.M. and Hulsebosch, C.E. p38 MAP

kinase inhibition attenuates central neuropathic pain following spinal cord injury in rats. Soc. Neurosci., 2007.

210. Hulsebosch, C.E., Ye, Z., Gwak, Y.S. and Crown, E.D. Reactive oxygen species

(ROS) play a critical role in persistence of central neuropathic pain after spinal cord injury (SCI). Soc. Neurosci., 2007.

211. Carter, M.W. and Hulsebosch, C.E. Inhibition of neutrophil extravasation after

spinal cord injury (SCI) by post-injury treatment with recombinant neutrophil inhibitory factor (rNIF) alters cytokine expression in spinal tissue at the injury site as well as systemically. Soc. Neurosci., 2007.

212. Ye, Z., Unabia, G., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C.E. Increased

expression of the NMDA glutamate receptor subunits NR1, NR2A and NR2B in spinothalamic tract cells 35 days after spinal cord contusion injury. Soc. Neurosci., 2007.

213. Gwak, Y. and Hulsebosch, C.E. Free radical scavenger attenuates below level

central neuropathic pain following spinal cord injury. Soc. Neurosci., 2008. 214. Hulsebosch, C.E., Gwak, Y.S., Crown, E.D., Johnson, K.M., Nesic-Taylor, O., McAdoo, D.J. and Perez-Polo, J.R. IL-1 receptor antagonist attenuates mechanical

allodynia and central sensitization via decreased glial activation and IL-1β production after spinal cord injury. Soc. Neurosci., 2008.

215. Hulsebosch, C.E., Unabia, G.C., Kang, J., Auerbach, J.D. and Gwak, Y.S. Spatial and temporal activation patterns of astrocytes and microglia in the dorsal horn following spinal cord injury in rat. Soc. Neurosci., 2009. 216. Dewitt, D.S., Dash, P.K., Grill, R., Parsley, M.A., Unabia, G.C., Rea, C., Perez-Polo,

J.R. and Hulsebosch, C.E. Measures of neurological deficits after mild traumatic brain injury. Soc. Neurosci., 2009.


217. Gwak, Y., Unabia, G.C. and Hulsebosch, C.E. Calcium-independent phospholipase A2

modulates neuronal hyperexcitability following spinal cord injury in rat. Soc. Neurosci., 2009.

218. Gwak, Y., Unabia, G., Auerbach, J., Kang, J. and Hulsebosch, C.E. Spatial and

temporal activation of astrocytes and microglia in the dorsal horn following spinal cord injury in rat. Natl. Neurotrauma Soc., 2009.

219. Rooney, B.A. and Hulsebosch, C.E. The functional and neurostructural effects of

systemic Artemin administration following a bilateral lumbosacral dorsal root crush injury. Natl. Neurotrauma Soc., 2009.

220. Rooney, B.A. and Hulsebosch, C.E. Assessing the functional, neurostructural and

nociceptive effects of systemic artemin administration following a bilateral lumbosacral dorsal root crush injury in the rat. Soc. Neurosci., 2009.

221. Hulsebosch, C.E., DeWitt, D.S., Dash, P.K., Grill, R.J., Parsley, M.A., Unabia, G.C.,

Rea, H.C. and Perez-Polo, J.R. Role of IL-1 and TNF receptor activation in neurological deficits after TBI. Natl. Neurotrauma Soc., 2009.

222. Perez-Polo, J.R., DeWitt, D.S., Rea, H.C., Dash, P.K., Grill, J., Parsley, M.A., Unabia,

G.C. and Hulsebosch, C.E. Anti-inflammatory treatment of traumatic brain injury (TBI). Soc. Neurosci., 2009.

223. Rooney, B.A. and Hulsebosch, C.E. Artemin induced axonal regeneration across the

drez promotes improvements in bladder function and delays the increased expression of phosphacan. Natl. Neurotrauma Soc., 2010.

224. Leem, J.W., Kim, H.K., Hulsebosch, C.E. and Gwak, Y.S. Ionotropic glutamate

contribute to the maintenance of below-level neuropathic pain following spinal cord injury in rat. Natl. Neurotrauma Soc., 2010.

225. Hassler, S., Ma., H., Kaphalia, B., Khan, F., Nauduri, D. and Hulsebosch, C.E.

Oxidative stress in acute spinal cord injury: measures of lipid peroxidation and protein oxidation products. Natl. Neurotrauma Soc., 2010.

226. Hulsebosch, C.E., Xu, G-Y., Johnson, K.M., Rea, H.C., Unabia, G.C., Nesic, O. and

Perez-Polo, J.R. DNA “decoy” treatment improves recovery of spinal cord injured rats. Natl. Neurotrauma Soc., 2010.

227. Johnson, K.M., Rea, H.C., Dewitt, D.S., Grill, R.J., Parsley, M.A., White, M.M., Unabia,

G.C., Hulsebosch, C.E. and Perez-Polo, J.R. Specific inflammatory mediators play critical roles in neurological deficits after TBI. Natl. Neurotrauma Soc., 2010.

228. Xu, G-Y., Gwak, Y.S., Johnson, K.M., Crown, E.D., Nesic, O., Perez-Polo, J.R. and

Hulsebosch, C.E. IL-1 receptor antagonist attenuates mechanical allodynia and central sensitization in chronic spinal cord injury (SCI). Soc. Neurosci., 2010.


229. Hulsebosch, C.E., Xu, G-Y., Johnson, K.M., Unabia, G.C., Nesic, O. and Perez-Polo, J. Treatment with DNA “decoy” that targets Cox-2 gene promoter improves behavioral recovery after spinal cord injury in rats. Soc. Neurosci., 2010.

230. Perez-Polo, J.R., Rea, H.C., White, M.M., Johnson, K.M., Grill, R., DeWitt, D. and

Hulsebosch, C.E. Outcomes of mild traumatic brain injury in a rodent model. Soc. Neurosci., 2010.

231. Rea, H.C., DeWitt, D.S., Dash, P.K., Grill, R.J., Parsley, M., Unabia, G., Hulsebosch,

C.E. and Perez-Polo, J.R. Inflammatory mediators after TBI. Am. Soc. Neurochem., 2010.

232. Gwak, Y.S., Hassler, S.N. and Hulsebosch, C.E. Reactive oxygen species modulate

central neuropathic pain following spinal cord injury. Soc. Neurosci., 2010. 233. Xu, G-Y., Johnson, K.M., Rea, H., Nesic, O., Hulsebosch, C.E. and Perez-Polo, J.R.

Inhibition of inflammation signaling by DNA “decoy” treatment improves sensory and motor recovery after spinal cord injury in rats by neuroprotection and microglial inhibition. Soc. Neurosci., 2011.

234. Hassler, S., Hulsebosch, C., Nauduri, D., Kaphalia, B., Khan, F. and Ma, H. Lipid

peroxidation and protein oxidation products are key factors in central neuropathic pain after spinal cord injury. Am. Pain Soc., 2011. J. Pain. 12 #4, Suppl. 2, P34.

235. Hulsebosch, C., Xu, G., Johnson, K., Unabia, G., Nesic-Taylor, O. and Perez-Polo, R.

Treatment with DNA “decoy” that targets COX-2 gene promoter improves mechanical and thermal allodynia after spinal cord injury in rats. Am. Pain Soc., 2011, J. Pain 12 #4, Suppl. 2, P41.

236. Gwak, Y., Hassler, S. and Hulsebosch, C. Reactive oxygen species (ROS) modulate

recovery of locomotion and central neuropathic pain following spinal cord injury. Am. Pain Soc., 2011, J. Pain 12 #4, Suppl. 2, P43.

237. Hulsebosch, C.E., Xu, G-Y., Gwak, Y.S., Johnson, K.M., Nesic, O. and Perez-Polo, R.

Inhibition of IL-1 receptor signaling attenuates mechanical allodynia, thermal and pressure hyperalgesia, central sensitization and both microglial and astrocytic activation after chronic spinal cord injury in rats. Soc. Neurosci. 2012.

238. Gwak, Y. and Hulsebosch, C. Reactive oxygen species (ROS) mediate neuropathic

pain signaling following spinal cord injury. Soc. Neurosci. 2012. 239. Hassler, S.N., Johnson, K.M. and Hulsebosch, C.E. Scavenging lipid peroxidation

products in chronic SCI rats reduces mechanical and thermal pain. Soc. Neurosci. 2012. 240. Nilsson, C.L., Nilsson, K.B., He,H., Liu,H., Shavkunov,A., Gwak,Y.S., Hassler, S.N.,

Johnson, K.M., Young, N.L., Marshall, A.G., Hulsebosch, C.E. Novel glycolipid markers of chronic pain following spinal cord injury. Soc. Neurosci., 2013.


B. Refereed Original Articles in Journals 1. Hulsebosch, C.E. and Bittner, G.D. Evolution of abilities to regenerate neurons in central

nervous systems. American Naturalist 115(2): 276-284, 1980. 2. Hulsebosch, C.E. and Bittner, G.D. Morphology and number of neurons in two species

of polychaetes. J. Comp. Neurol. 198: 65-75, 1981. 3. Hulsebosch, C.E. and Bittner, G.D. Regeneration of axons and nerve cell bodies in the

CNS of annelids. J. Comp. Neurol. 198: 77-88, 1981. 4. Hulsebosch, C.E. and Coggeshall, R.E. Quantitation of sprouting of dorsal root axons.

Science 213: 1020-1021, 1981. 5. Hulsebosch, C.E. and Coggeshall, R.E. Sprouting of dorsal root axons. Brain Res. 224:

170-174, 1981. 6. Hulsebosch, C.E. and Coggeshall, R.E. An analysis of axon populations in the nerves

to the pelvic viscera in the rat. J. Comp. Neurol. 211: 1-10, 1982. 7. Hulsebosch, C.E. and Coggeshall, R.E. A comparison of axonal numbers in dorsal roots

following spinal cord hemisection in neonate and adult rats. Brain Res. 265: 187-197, 1983.

8. Hulsebosch, C.E. and Coggeshall, R.E. Age related sprouting of dorsal root axons after

sensory denervation. Brain Res. 288: 77-83, 1983. 9. Hulsebosch, C.E., Perez-Polo, J.R. and Coggeshall, R.E. Effects of antibodies to nerve

growth factor on sprouting following spinal cord hemisection in the rat. Neurosci. Lett. 44: 19-23, 1984.

10. Jenq, C.B., Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R.The effects of

nerve growth factor and its antibodies on axonal numbers in the medial gastrocnemius nerve of the rat. Brain Res. 299: 9-14, 1984.

11. Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R. Increased numbers of thoracic

dorsal root axons in rats given antibodies to nerve growth factor. Science 225: 525-526, 1984.

12. Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R. Effects of nerve growth factor

and its antibodies on sprouting of sensory axons following spinal cord hemisection. Brain Res. 323: 1-10, 1984.

13. Coggeshall, R.E, Chung, K., Greenwood, D. and Hulsebosch, C.E. An empirical method

for converting nucleolar counts to neuronal numbers. J. Neurosci. Meth. 12: 125-132, 1984.

14. Greenwood, D., Coggeshall, R.E. and Hulsebosch, C.E. Sexual dimorphism in the


numbers of neurons in the pelvic ganglia of adult rats. Brain Res. 40: 160-162, 1985. 15. Hulsebosch, C.E., Coggeshall, R.E. and Chung, K. Numbers of rat dorsal root axons

and ganglion cells during postnatal development. Dev. Brain Res. 26: 105-113, 1986. 16. Heath, D.D., Coggeshall, R.E. and Hulsebosch, C.E. Axon and neuron numbers after

forelimb amputation in neonatal rat. Exp. Neurol. 92: 220-233, 1986. 17. Hulsebosch, C.E., Perez-Polo, J.R. and Coggeshall, R.E. In vivo anti-NGF induces

sprouting of sensory axons in dorsal roots. J. Comp. Neurol. 259: 445-451, 1987. 18. Hulsebosch, C.E., Coggeshall, R.E. and Perez-Polo, J.R. Persistence of anti-NGF

induced dorsal root axons: Possible penetration in the mammalian spinal cord. Brain Res. 411: 267-274, 1987.

19. McNeill, D.L. and Hulsebosch, C.E. Intraspinal sprouting of rat primary afferents after

deafferentation. Neurosci. Lett. 81: 57-62, 1987. 20. Angelucci, L., Ramacci, M.T., Taglialatela, G., Hulsebosch, C.E., Morgan, B., Werrbach-

Perez, K and Perez-Polo, R. Nerve growth factor binding in aged rat CNS: effect of acetyl-L-carnitine. J. Neurosci. Res. 20: 491-496, 1988.

21. Hulsebosch, C.E. and Coggeshall, R.E. Intraspinal sprouting after administration of

nerve growth factor antibodies to neonatal rats. Brain Res. 461: 322-327, 1988. 22. McNeill, D.L., Chung, K., Hulsebosch, C.E., Bolender, R.P. and Coggeshall, R.E.

Numbers of synapses in laminae I-IV of the rat dorsal horn. J. Comp. Neurol. 278: 453-460, 1988.

23. Chung, K., McNeill, D.L., Hulsebosch, C.E. and Coggeshall, R.E. Changes in dorsal

horn synaptic disc numbers following unilateral dorsal rhizotomy. J. Comp. Neurol. 283: 568-577, 1989.

24. Hulsebosch, C.E. and Fabian, R.H. Penetration of IgGs into the neuraxis of the neonatal

rat. Neurosci. Lett. 98: 13-18, 1989. 25. Fabian, R.H. and Hulsebosch, C.E. Time course of penetration of xenogeneic IgG into

the central nervous system of the neonatal rat: an immunohistochemical and radionuclide tracer study. J. Neuroimmunol. 24: 183-189, 1989.

26. Stamps, W.T., Coggeshall, R.E. and Hulsebosch, C.E. Computerized ultrastructural

analysis of the shape of the active synaptic zones in rat spinal cord. Exp. Neurol. 108: 151-155, 1990.

27. McNeill, D.L., Carlton, S.M., Coggeshall, R.E. and Hulsebosch, C.E. Denervation

induced intraspinal synaptogenesis of calcitonin gene-related peptide containing primary afferent terminals. J. Comp. Neurol. 296: 263-268, 1990.

28. Urschel, B.A. and Hulsebosch, C.E. Schwann cell-neuronal interactions in the rat involve


nerve growth factor. J. Comp. Neurol. 296: 114-122, 1990. 29. Urschel, B.A. and Hulsebosch, C.E. In vivo recovery of Schwann cell-neuronal

interactions altered by nerve growth factor suppression in the rat. Neurosci. Lett. 117: 50-55, 1990.

30. Urschel, B.A., Brown, P.N. and Hulsebosch, C.E. Differential effects on sensory nerve

processes and behavioral alterations in the rat after treatment with antibodies to Nerve Growth Factor. Exp. Neurol. 114: 44-52, 1991.

31. McNeill, D.L., Carlton, S.M. and Hulsebosch, C.E. Intraspinal sprouting of calcitonin

gene-related peptide containing primary afferents after deafferentation in the rat. Exp. Neurol. 114: 321-329, 1991.

32. Urschel, B.A. and Hulsebosch, C.E. Distribution and relative density of p75 nerve factor

receptors in the rat brain as a function of age and treatment with antibodies to nerve growth factor. Brain Res. 591: 223-238, 1992.

33. Urschel, B.A. and Hulsebosch, C.E. Distribution and relative density of p75 nerve factor

receptors in the rat spinal cord as a function of age and treatment with antibodies to nerve growth factor. Devel. Brain Res. 69: 261-270, 1992.

34. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Increase in synaptophysin

immunoreactivity following cortical infarction. Neurosci. Lett. 147: 21-24, 1992. 35. Westlund, K.N., Lu, Y., Werrbach-Perez, K., Hulsebosch, C.E., Morgan, B., Pizzo, D.,

Eisenberg, H.M. and Perez-Polo, J.R. Effects of nerve growth factor and acetyl-l-carnitine arginyl amide on the human neuronal line HCN-1A. Intl. J. of Devel. Neurosci. 10: 361-373, 1992.

36. Fabian, R.H. and Hulsebosch, C.E. Plasma nerve growth factor access to the postnatal

central nervous system. Brain Res. 611: 46-52, 1993. 37. Zompa, E.A., Pizzo, D.P. and Hulsebosch, C.E. Migration and differentiation of PC12

cells transplanted into the rat spinal cord. Int J. Devel. Neurosc. 11:(5): 535-544, 1993. 38. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Acute increases in GAP-43 expression

following cortical ischemia. Neurosci. Lett. 162: 51-54, 1993. 39. Collins, T.J., Given, R.L., Hulsebosch, C.E. and Miller, B.T. Status of gross anatomy in

the U.S. and Canada: Dilemma for the 21st century. Clinical Anatomy 7: 275-296, 1994. 40. Westlund, K.N., Lu, Y., Kadekaro, M., Harmann, P., Terrell, M.L., Pizzo, D., Hulsebosch,

C.E., Eisenberg, H.M. and Perez-Polo, J.R. NGF-producing transfected 3T3 cells: Behavioral and histological assessment of transplants in nigral lesioned rats. J. Neurosci. Res. 41: 367-373, 1995.

41. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Neocortical neural sprouting,

synaptogenesis and behavioral recovery following neocortical infarction in rats. Stroke


26: 2135-2144, 1995. 42. Christensen, M.D., Everhart, A.W., Pickelmann, J.T. and Hulsebosch, C.E. Mechanical

allodynia and thermal hyperalgesia in chronic central pain following spinal cord injury. Pain 68: 97-107, 1996.

43. Moyer, M.P., Johnson, R.A., Zompa, E.A., Cain, L., Morshed, T. and Hulsebosch, C.E.

Culture, expansion, and transplantation of human fetal neural progenitor cells. Transplantation Proceedings 29: 2040-2041, 1997.

44. Hulsebosch, C.E., Sherwood, A.M. and Waldrep, K. Spinal cord injury: Bridging the gap

and prospects for recovery. J. Neurotrauma 14: 477-478, 1997. 45. Zompa, E.A, Cain, L.D., Everhart, A.W., Moyer, M.P. and Hulsebosch, C.E. Transplant

therapy: Recovery of function after spinal cord injury. J. Neurotrauma 14: 479-506, 1997. 46. Christensen, M.D. and Hulsebosch, C.E. Chronic central pain after spinal cord injury. J.

Neurotrauma 14: 517-537, 1997. 47. Christensen, M.D. and Hulsebosch, C.E. Spinal cord injury and anti-NGF treatment

results in changes in CGRP density and distribution in the dorsal horn in the rat. Exp. Neurol. 147: 463-475, 1997.

48. Stroemer, R.P., Kent, T.A. and Hulsebosch, C.E. Enhanced neocortical neural

sprouting, synaptogenesis, and behavioral recovery with D-amphetamine therapy after neocortical infarction in rats. Stroke 29: 2381-2395, 1998.

49. Zompa, E.A., Moyer, M.P., Cain, L.D., Bottenstein, J.E. and Hulsebosch, C.E. A rapid

and sensitive method for detecting human cells in xenogeneic hosts. Transplantation 66: 928-931, 1998.

50. Hulsebosch, C.E., DeWitt, D.S., Jenkins, L.W. and Prough, D.S. Traumatic brain injury

in rats results in increased expression of Gap-43 that correlates with behavioral recovery. Neurosci. Lett. 255: 83-86, 1998.

51. Bennett, A.D., Taglialatela, G., Perez-Polo, R. and Hulsebosch, C.E. NGF levels

decrease in the spinal cord and dorsal root ganglion after spinal hemisection. NeuroReport 10: 889-893, 1999.

52. Hulsebosch, C.E. Amphetamine-facilitated poststroke recovery. Stroke 30: 696-698,

1999. 53. Bennett, A.D., Everhart, A.W. and Hulsebosch, C.E. Intrathecal administration of an

NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury. Brain Res. 859: 72-82, 2000.

54. Bennett, A.D., Chastain, K.M. and Hulsebosch, C.E. Alleviation of mechanical and

thermal allodynia by CGRP8-37 in a rodent model of chronic central pain. Pain 86: 163-


175, 2000. 55. Hains, B.C., Chastain, K.M., Everhart, A.W., McAdoo, D.J. and Hulsebosch, C.E.

Transplants of adrenal medullary chromaffin cells reduce forelimb and hindlimb allodynia in a rodent model of chronic central pain after spinal cord hemisection injury. Exp. Neurol. 164: 426-437, 2000.

56. Mills, C.D., Xu, G-Y., Johnson, K.M., McAdoo, D.J. and Hulsebosch, C.E. AIDA reduces

glutamate release and attenuates mechanical allodynia after spinal cord injury. NeuroReport 11: 3067-3070, 2000.

57. Hulsebosch, C.E., Xu, G-Y., Perez-Polo, J.R., Westlund, K.N., Taylor, C.P. and McAdoo,

D.J. Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin. J. Neurotrauma 17: 1205-1217, 2000.

58. Hulsebosch, C.E., Hains, B.C., Waldrep, K. and Young, W. Bridging the gap: From

discovery to clinical trials in spinal cord injury. J. Neurotrauma 17: 1117-1128, 2000. 59. Hains, B.C., Yucra, J.A. and Hulsebosch, C.E. Reduction of pathological and behavioral

deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398. J. Neurotrauma 18: 409-423, 2001.

60. Mills, C.D., Fullwood, S.D. and Hulsebosch, C.E. Changes in metabotropic glutamate

receptor expression following spinal cord injury. Exp. Neurol. 170: 244-257, 2001. 61. Mills, C.D., Hains, B.C., Johnson, K.M. and Hulsebosch, C.E. Strain and model

differences in behavioral outcomes after spinal cord injury in rat. J. Neurotrauma 18: 743-756, 2001.

62. Mills, C.D., Grady, J.J. and Hulsebosch, C.E. Changes in exploratory behavior as a

measure of chronic central pain following spinal cord injury. J. Neurotrauma 18: 1091-1105, 2001.

63. Nesic, O., Xu, G-Y., McAdoo, D., High, K.W., Hulsebosch, C. and Perez-Polo, R. IL-1

receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury. J. Neurotrauma 18: 947-956, 2001.

64. Hains, B.C., Fullwood, S.D., Eaton, M.J. and Hulsebosch, C.E. Subdural engraftment of

serotonergic neurons following spinal hemisection restores spinal serotonin, downregulates serotonin transporter, and increases BDNF tissue content in rat. Brain Res. 913: 35-46, 2001.

65. Hains., B.C., Johnson, K.M., McAdoo, D.J., Eaton, M.J. and Hulsebosch, C.E.

Engraftment of serotonergic precursors enhances locmotor function and attenuates chronic central pain behavior following spinal hemisection injury in the rat. Exp. Neurol. 171: 361-378, 2001.

66. Mills, C.D., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C.E. Involvment of metabotropic

glutamate receptors in excitatory amino acid and GABA release following spinal cord


injury in rat. J. Neurochem. 79: 835-848, 2001. 67. Qiu, J., Nesic, O., Ye, Z., Rea, H., Westlund, K.N., Xu, G-Y., McAdoo, D., Hulsebosch,

C.E. and Perez-Polo, J.R. Bcl-xL expression after contusion to the rat spinal cord. J. Neurotrauma 18: 1267-1278, 2001.

68. Mills, C.D., Johnson, K.M. and Hulsebosch, C.E. Group I metabotropic glutamate

receptors in spinal cord injury: Roles in neuroprotection and the development of chronic central pain. J. Neurotrauma 19: 23-42, 2002.

69. Mills, C.D., Johnson, K.M. and Hulsebosch, C.E. Role of group II and group III

metabotropic glutamate receptors in spinal cord injury. Exp. Neurol. 173: 153-167, 2002. 70. Vera-Portocarrero, L.P., Mills, C.D., Ye, Zaiming, Fullwood, S.D., McAdoo, D.J.,

Hulsebosch, C.E. and Westlund, K.N. Rapid changes in expression of glutamate transporters after spinal cord injury. Brain Res. 927: 104-110, 2002.

71. Mills, C.D. and Hulsebosch, C.E. Increased expression of metabotropic glutamate

receptor subtype 1 on spinothalamic tract neurons following spinal cord injury in the rat. Neurosci. Lett. 319: 59-62, 2002.

72. Hains, B.C., Willis, W.D. and Hulsebosch, C.E. Differential electrophysiological effects

of brain-derived neurotrophic factor on dorsal horn neurons following chronic spinal cord hemisection injury in the rat. Neurosci. Lett. 320: 125-128, 2002.

73. Nesic, O., Svrakic, N.M., Xu, G-Y., McAdoo, D., Westlund, K.N., Hulsebosch, C.E., Ye,

Z., Galante, A., Soteropoulos, P., Tolias, P., Young, W., Hart, R.P. and Perez-Polo, J.R. DNA microarray analysis of the contused spinal cord: Effect of NMDA receptor inhibition. J. Neurosci. Res. 68: 406-423, 2002.

74. Hains, B.C., Everhart, A.W., Fullwood, S.D. and Hulsebosch, C.E. Changes in serotonin,

serotonin transporter expression and serotonin denervation supersensitivity: Involvement in chronic central pain after spinal hemisection in the rat. Exp. Neurol. 175: 347-362, 2002.

75. Hains, B.C., Yucra, J.A., Eaton, M.J. and Hulsebosch, C.E. Intralesion transplantation of

serotonergic precursors enhances locomotor recovery but has no effect on development of chronic central pain following hemisection injury in rats. Neurosci. Lett. 324: 222-226, 2002.

76. Hulsebosch, C.E. Recent advances in pathophysiology and treatment of spinal cord

injury. Adv. Physiol. Edu. 26: 238-255, 2002. 77. Hains, B.C., Johnson, K.M., Eaton, M.J., Willis, W.D. and Hulsebosch, C.E. Serotonergic

neural precursor cell grafts attenuate bilateral hyperexcitability of dorsal horn neurons after spinal hemisection in rat. Neuroscience 116: 1097-1110, 2003.

78. Gwak, Y.S., Nam, T.S., Paik, K.S., Hulsebosch, C.E. and Leem, J.W. Attenuation of

mechanical hyperalgesia following spinal cord injury by administration of antibodies to


nerve growth factor in the rat. Neurosci. Lett. 336: 117-120, 2003. 79. Hains, B.C., Willis, W.D. and Hulsebosch, C.E. Serotonin receptors 5-HT1A and 5-HT3

reduce hyperexcitability of dorsal horn neurons after chronic spinal cord hemisection injury in rat. Exp. Brain Res. 149: 174-186, 2003.

80. Hulsebosch, C.E. Mechanisms and treatment strategies for chronic central neuropathic

pain after spinal cord injury. Top. Spinal Cord Inj. Rehabil. 8: 76-91, 2003. 81. Hains, B.C., Willis, W.D. and Hulssebosch, C.E. Temporal plasticity of dorsal horn

somatosensory neurons after acute and chronic spinal cord hemisection in rat. Brain Res. 970: 238-241, 2003.

82. Ondarza, A.B., Ye, Z. and Hulsebosch, C.E. Direct evidence of primary afferent

sprouting in distant segments following spinal cord injury in the rat: colocalization of GAP-43 and CGRP. Exp. Neurol. 184: 373-380, 2003.

83. Hulsebosch, C.E. Central sensitization and pain after spinal cord injury. Sem. Pain Med.

1: 159-170, 2003. 84. Gwak, Y.S., Hains, B.C., Johnson, K.M. and Hulsebosch C.E. Locomotor recovery and

mechanical hyperalgesia following spinal cord injury depend on age at time of injury in rat. Neurosci. Lett. 362: 232-235, 2004.

85. Xu, G-Y., Hughes, M.G., Ye, Z., Hulsebosch, C.E. and McAdoo, D.J. Concentrations of

glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord. Exp. Neurol. 187: 329-336, 2004.

86. Gwak, Y.S., Hains, B.C., Johnson, K.M. and Hulsebosch, C.E. Effect of age at time of

spinal cord injury on behavioral outcomes in rat. J. Neurotrauma 21: 983-993, 2004. 87.Nesic-Taylor, O., Cittelly, D., Ye, Z., Xu, G-Y., Unabia, G., Lee, J.C., Svrakic, N.M., Liu,

X-H., Youle, R.J., Wood, T.G., McAdoo, D., Westlund, K.N., Hulsebosch, C.E. and Perez-Polo, J.R. Exogenous BCL-X(L) fusion spares neurons after spinal cord injury. J. Neurosci. Res. 79: 628-637, 2005.

88. McAdoo, D.J., Hughes, M.G., Nie, L., Shah, B., Clifton, C., Fullwood, S. and Hulsebosch, C.E. The effect of glutamate receptor blockers on glutamate release following spinal cord injury. Lack of evidence for an ongoing feedback cascade of damage → glutamate release → damage → glutamate release → etc. Brain Res. 1038: 92-99, 2005.

89. Hulsebosch, C.E. From discovery to clinical trials: Treatment strategies for central

neuropathic pain after spinal cord injury. Current Pharmaceutical Design 11: 1411-1420, 2005.

90. Crown, E.D., Ye, Z., Johnson, K.M., Xu, G-Y., McAdoo, D.J., Westlund, K.N., and

Hulsebosch, C.E. Upregulation of the phosphorylated form of CREB in spinothalamic tract cells following spinal cord injury: Relation to central neuropathic pain. Neurosci Lett. (12) 384:139-44, 2005.


91. Gwak, Y.S. and Hulsebosch, C.E. Upregulation of Group I metabotropic glutamate

receptors in neurons and astrocytes in the dorsal horn following spinal cord injury. Exp Neurol. 195: 236-243, 2005.

92. Dussor, G.O., Jones, D.J., Hulsebosch, C.E., Edell, T.A. and Flores, C.M. The effects of

chemical or surgical deafferentation on [3H]-acetylcholine release from rat spinal cord. Neuroscience 135: 1269-1276, 2005.

93. Nesic, O., Lee, J., Johnson, K.M., Ye, Z., Xu, G-Y., Unabia, G.C., Wood, T.G., McAdoo,

D.J., Westlund, K.N., Hulsebosch, C.E. and Perez-Polo, J.R. Transcriptional profiling of spinal cord injury-induced central neuropathic pain. J. Neurochem. 95: 998-1014, 2005.

94. Nesic-Taylor, O., Cittelly, D., Ye, Z., Xu, G-Y., Unabia, G., Lee, J.C., Svrakic, N.M., Liu,

X-H., Youle, R.J., Wood, T.G., McAdoo, D.J., Westlund, K.N., Hulsebosch, C.E. and Perez-Polo, J.R. Exogenous Bcl-xL fusion protein spares neurons after spinal cord injuty. J. Neurosci. Res. 79: 628-637, 2005.

95. Crown, E.D., Ye, Z., Johnson, K.M., Xu, G-Y., McAdoo, D.J. and Hulsebosch, C.E.

Increases in the activated forms of ERK ½, p38 MAPK, and CREB are correlated with the expression of at-level mechanical allodynia following spinal cord injury. Exp. Neurol. 199: 397-407, 2006.

96. Gwak, Y.S., Tan, H., Nam, T.S., Paik, K.S., Hulsebosch, C.E. and Leem, J.W. Activation

of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury. J. Neurotrauma 23: 1111-1124, 2006.

97. Nesic, O., Lee, J., Ye, Z., Unabia, G.C., Rafati, D., Hulsebosch, C.E. and Perez-Polo,

J.R. Acute and chronic changes in aquaporin 4 expression after spinal cord injury. Neuroscience 143: 779-792, 2006. PMCID: PMC1894918

98. Tarasenko, Y.I., Gao, J., Nie, L., Johnson, K.M., Grady, J.J., Hulsebosch, C.E., McAdoo,

D.J. and Wu, P. Human fetal neural stem cells grafted into contusion-injured rat spinal cords improve behavior. J. Neurosci. Res. 85: 47-57, 2007.

99. Rooney, B.A., Crown, E.D., Hulsebosch, C.E. and McAdoo, D.J. Preemptive analgesia

with lidocaine prevents failed back surgery syndrome. Exp. Neurol. 204: 589-596, 2007.

100. Cain, L.D., Nie, L., Hughes, M.G., Johnson, K., Echetebu, C., Xu, G-Y., Hulsebosch, C.E. and McAdoo, D.J. Serum albumin improves recovery from spinal cord injury. J. Neurosci. Res. 85: 1558-1567, 2007.

101. Gwak, Y.S., Kang, J., Leem, J.W. and Hulsebosch, C.E. Spinal AMPA receptor

inhibition attenuates mechanical allodynia and neuronal hyperexcitability following spinal cord injury in rats. J. Neurosci. Res. 85: 2352-2359, 2007.

102. Rafati, D.S., Geissler, K., Johnson, K., Unabia, G., Hulsebosch, C., Nesic-Taylor, O.

and Perez-Polo, J.R. Nuclear factor-kappaB decoy amelioration of spinal cord injury-


induced inflammation and behavior outcomes. J. Neurosci. Res. 86: 566-580, 2008. 103. Cittelly, D.M., Nesic, O., Johnson, K., Hulsebosch, C. and Perez-Polo, J.R. Detrimental

effects of antiapoptotic treatments in spinal cord injury. Exp. Neurol. 210: 295-307, 2008. 104. Nesic, O., Lee, J., Unabia, G.C., Johnson, K., Ye, Z., Vergara, L., Hulsebosch, C.E.

and Perez-Polo, J.R. Aquaporin 1 – a novel player in spinal cord injury. J. Neurochem. 105: 628-640, 2008. PMCID: PMC2634749

105. Gwak, Y.S., Crown, E.D., Unabia, G.C. and Hulsebosch, C.E. Propentofylline

attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat. Pain 138: 410-422, 2008. PMCID: PMC2676790

106. Crown, E.D., Gwak, Y.S., Ye, Z., Johnson, K.M. and Hulsebosch, C.E. Activation of

p38 MAP kinase is involved in central neuropathic pain following spinal cord injury. Exp. Neurol. 213: 257-267, 2008. PMCID: PMC2580737

107. Liu, S., Xu, G-Y., Johnson, K.M., Echetebu, C., Ye, Z.S., Hulsebosch, C.E. and

McAdoo, D.J. Regulation of interleukin-1 beta by the interleukin-1 receptor antagonist in the glutamate-injured spinal cord: Endogenous neuroprotection. Brain Res. 1231: 63-74, 2008.

108. Hulsebosch, C.E. Gliopathy ensures persistent inflammation and chronic pain after

spinal cord injury. Exp. Neurol. 214: 6-9, 2008. PMCID: PMC2888707 109. Hulsebosch, C.E., Hains, B.C., Crown, E.D. and Carlton, S.M. Mechanisms of chronical

central neuropathic pain after spinal cord injury. Brain Res. Rev. 60: 202-213, 2009. PMCID: PMC2796975

110. Gwak, Y.S. and Hulsebosch, C.E. Remote astrocytic and microglial activation

modulates neuronal hyperexcitability and below-level neuropathic pain after spinal injury in rat. Neuroscience 161: 895-903, 2009. PMCID: PMC3005301.

111. Gwak, Y.S., Unabia, G.C. and Hulsebosch, C.E. Activation of p-38alpha MAPK

contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury. Exp. Neurol. 220: 154-161, 2009. PMCID: PMC3008350.

112. Carlton, S.M., Du, J., Tan, HY, Nesic, O., Hargett, G.L., Bopp, A.C., Yamani, A., Lin,

Q., Willis, W.D. and Hulsebosch, C.E. Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury. Pain 147: 265-276, 2009. PMCID: PMC2787843.

113. Leem, J.W., Kim, H.K., Hulsebosch, C.E. and Gwak, Y.S. Ionotropic glutamate

receptors contribute to maintained neuronal hyperexcitability following spinal cord injury in rats. Exp. Neurol. 224: 321-324, 2010. PMCID: PMC3008557.

114. Gwak, Y.S. and Hulsebosch, C.E. GABA and central neuropathic pain following spinal

cord injury. Neuropharm. 60: 799-808, 2011. PMCID: PMC3285561.


115. Gwak, Y.S. and Hulsebosch, C.E. Neuronal hyperexcitability: A substrate for central neuropathic pain after spinal cord injury. Curr. Pain Headachc Rep. 15: 215-222, 2011. PMID: 21387163.

116. Gwak, Y.S., Kang, J., Unabia, G.C. and Hulsebosch, C.E. Spatial and temporal

activation of spinal glial cells: Role of gliopathy in central neuropathic pain following spinal cord injury in rats. Exp. Neurol. 234: 362-372, 2012. PMCID: PMC3303938.

117. Hulsebosch, C.E. Special issue on microglia and chronic pain. Exp. Neurol. 234: 253-

254, 2012. PMID: 22285249. 118. Crown, E.D., Gwak, Y.S., Ye, Z., Tan, H.Y., Johnson, K.M., Xu, G-Y., McAdoo, D.J.

and Hulsebosch, C.E. Calcium/calmodulin dependent kinase II contributes to persistent central neuropathic pain following spinal cord injury. Pain 153: 710-721, 2012. PMCID: PMC3367863.

119. Dewitt, D., Perez-Polo, J.R., Hulsebosch, C.E., Dash, P.K. and Robertson, C.S.

Challenges in the development of rodent models of mild traumatic brain injury. J. Neurotrauma, 30: 688-701, 2013. PMID: 23286417.

120. Perez-Polo, J.R., Rea, H.C., Johnson, K.M., Parsley, M.A., Unabia, G.C., Xu, G-Y.,

Infante, S.K., DeWitt, D.S. and Hulsebosch, C.E. Inflammatory consequences in a rodent model of mild traumatic brain injury. J. Neurotrauma 30: 727-740, 2013. PMID: 23360201.

121. Robertson, C.S. and Hulsebosch, C.E. Studies of mild traumatic brain injury. J.

Neurotrauma 30: 609, 2013. PMID: 23621646. 122. Robertson, C.S. and Hulsebosch, C.E. Studies of mild traumatic brain injury. J.

Neurotrauma 30: 687, 2013. PMID: 23662620. 123. Gwak, Y.S., Hassler, S.E. and Hulsebosch, C.E. Reactive oxygen species contribute

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124. Lemmon VP1, Ferguson AR, Popovich PG, Xu XM, Snow DM, Igarashi M, Beattie CE,

Bixby JL, Consortium M, Abeyruwan SW, Beattie MS, Bethea J, Bradke F, Bresnahan JC, Bunge MB, Callahan A, David S, Dunlop SA, Fawcett J, Fehlings M, Fischer I, Giger RJ, Goshima Y, Grimpe B, Hagg T, Hall ED, Harrison BJ, Harvey AR, He C, He Z, Hirata T, Hoke A, Hulsebosch CE, Hurtado A, Jain A, Kadoya K, Kamiguchi H, Kengaku M, Kocsis JD Ph D, Kwon BK, Lee JK, Liebl DJ PhD, Liu SJ, Lowery LA, Mandrekar-Colucci S, Martin JH, Mason CA, McTigue DM, Mokarram N, Moon LD, Muller HW, Nakamura T, Namba T, Nishibe M, Oinuma I, Oudega M, Pleasure DE, Raisman G, Rasband MN, Reier PJ, Santiago-Medina M, Schwab JM, Schwab ME, Shinmyo Y, Silver J, Smith GM, So KF, Sofroniew MV Md PhD, Strittmatter SM, Tuszynski MH, Twiss JL, Visser U, Watkins TA, Wu W, Yoon SO, Yuzaki M, Zheng B, Zhou F, Zou Y. Minimum information about a spinal cord injury Experiment (MIASCI) - a proposed reporting standard for spinal cord injury experiments. J Neurotrauma. 2014 May 28. [Epub ahead of print]. PMID: 2487006.


125. Hassler SN, Johnson KM, Hulsebosch CE. Reactive oxygen species and lipid

peroxidation inhibitors reduce mechanical sensitivity in a chronic neuropathic pain model of spinal cord injury in rats. J Neurochem. 2014 Nov;131(4):413-7. PMID: 25051888.

126. Perez-Polo JR, Rea HC, Johnson KM, Parsley MA, Unabia GC, Xu GY, Prough D,

DeWitt DS, Spratt H, Hulsebosch CE. A rodent model of mild traumatic brain blast injury. J Neurosci Res. 2015 Apr;93(4):549-61. PMID: 25410497.

127. Perez-Polo JR, Rea HC, Johnson KM, Parsley MA, Unabia GC, Xu GY, Prough D,

DeWitt DS, Paulucci-Holthauzen AA, Werrbach-Perez K, Hulsebosch CE. Inflammatory cytokine receptor blockade in a rodent model of mild traumatic brain injury. J Neurosci Res. 2016 Jan;94(1):27-38. doi: 10.1002/jnr.23617. Epub 2015 Jul 14.

128. Carter MW, Johnson KM, Lee JY, Hulsebosch CE, Gwak YS. Comparison of

Mechanical Allodynia and Recovery of Locomotion and Bladder Function by Different Parameters of Low Thoracic Spinal Contusion Injury in Rats. Korean J Pain. 2016 Apr;29(2):86-95. doi: 10.3344/kjp.2016.29.2.86. Epub 2016 Apr 1.PMID: 27103963.

129. Gwak YS, Hulsebosch CE, Leem, JW. Neuronal-Glial Interactions Maintain

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Dissertation Hulsebosch, C.E. Regeneration of Axons and Cell Bodies in the Central Nervous System of Annelids - A Test of the Neuron Addition Hypothesis. Ph.D. Dissertation, University of Texas at Austin, Austin, Texas, 1979. C. Book Chapters 1. Coggeshall, R.E. and Hulsebosch, C.E. Sprouting of unmyelinated dorsal root axons in

response to spinal or dorsal root injury. In: ADVANCES IN PAIN RESEARCH AND THERAPY, Vol. 5, J. Bonica et al. (eds.), Raven Press, New York, pp. 125-129, 1983.

2. Hulsebosch, C.E. Spinal cord injury: A basic research approach. In: PARAPLEGIA

NEW (December Issue), pp. 27-29, 1983. 3. Hulsebosch, C.E. The influence of denervation and nerve growth factor on dorsal root

axonal sprouting. In: PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH, Vol. 176, CONTEMPORARY SENSORY NEUROBIOLOGY, M.J. Correia and A.A. Perachio (eds.). Alan R. Liss, New York, pp. 163-170, 1985.

4. Hulsebosch, C.E. Spinal cord synaptogenesis in response to deafferentation and

alterations in nerve growth factor. In: PARAPLEGIA NEWS, January, p. 37, 1988.

http://www.ncbi.nlm.nih.gov/pubmed/26172557





5. Hulsebosch, C.E. Intraspinal sprouting of primary afferents after spinal denervation and treatment with antibodies to nerve growth factor. In: NEURAL DEVELOPMENT AND REGENERATION: CELLULAR AND MOLECULAR ASPECTS. A. Gorio, J. deVillis, J.R. Perez-Polo and B. Haber (eds.). NATO Meeting, 1988, pp. 385-398.

6. Stamps, W.T. and Hulsebosch, C.E. Computerized three-dimensional analysis of the

shape of synaptic active zone in rat spinal cord. In: METHODS IN NEUROSCIENCES. P. Michael Conn (ed.), 1992, vol. 10, pp. 350-362.

7. Hulsebosch, C.E. Working toward a cure for pain after spinal cord injury. In: One Step

Closer to Home for Spinal Victory, Spring, 1997. 8. Hulsebosch, C.E. Pharmacology of chronic pain after spinal cord injury: Novel acute and

chronic intervention strategies. In: SPINAL CORD INJURY PAIN: ASSESSMENT, MECHANISMS, MANAGEMENT. PROGRESS IN PAIN RESEARCH AND MANAGEMENT, R.P. Yezierski and K.J. Burchiel (eds.), vol. 23, chapter 11, IASP Press, Seattle, 189-204, 2002.

9. Hulsebosch, Claire E. Spinal cord injury pain model/hemisection model. In:

ENCYCLOPEDIC REFERENCE OF PAIN, 2006. 10. Gwak, Y.S. and Hulsebosch, C.E. “Gliopathy” maintains persistent hyperexcitability of

spinal dorsal horn neurons after spinal cord injury: Substrate of central neuropathic pain. In: Horizons in Neuroscience Research, A. Costa and E. Villalba (eds.), vol. 1, chapter 5, Nova Science Publ., New York, 195-224, 2010.

D. Other Professional Communications: Neuronal Addition System and Central Nervous System Regeneration: A Casual or Causal

Correlation?, University of Texas Medical Branch at Galveston, October 1979 Neuronal Addition System and Central Nervous System Regeneration: A Casual or Causal

Correlation?, Rice University, May 1980 Women in Science, Texas A&M at Galveston, October 1980 Sprouting of unmyelinated dorsal root axons in response to spinal or dorsal root injury, Third

World Congress of Pain, Edinburgh, Scotland, August, 1981 Innervation of Pelvic Structures, University of Texas at Houston, October 1982 Neurotrophic Factors: A Recapitulation of Neural Development, Texas Women's University,

October, 1987 Cellular and Molecular Aspects of Neural Development and Regeneration, NATO Advanced

Research Workshop, Bal Harbour, FL, June 1987 Underlying Mechanisms and Clinical Perspectives, Recovery of Function After Spinal Cord

Injury, Pittsburgh, PA, 1988 Neurotrophic Factors: A Recapitulation of Neural Development, Knight Foundation Lecturer,

Miami, FL, 1988 The Cell, Hunter's Creek Elementary School, Houston, 1988 Neurotrophic Factors: A Recapitulation of Neural Development, University of Texas Medical

Branch at Galveston, Department of Pharmacology and Toxicology, October 1988 The Right to Use Animals in Research, University of Texas Medical Branch at Galveston,


December 1989 Neural Regeneration: A Recapitulation of Neural Development, University of Texas at

Austin, January 1990 Neural Regeneration: A Recapitulation of Neural Development, University of Texas Medical

Branch at Galveston, March 1990 Central Nervous System Regeneration, University of Texas Medical Branch at Galveston,

Department of Neurosurgery, March 1990 Neural Regeneration: A Recapitulation of Neural Development, University of Texas at

Houston, May 1990 Morphological Correlates of Synaptic Organization in the Dorsal Horn, Workshop, University

of Texas Health Science Center at Houston, March 1991 Neural Transplantation in the Central Nervous System, University of Texas at

Austin, April 1991 Intraspinal Sprouting of Primary Afferent Fibers, University of Texas Medical Branch at Galveston, Pathology Grand Rounds, November 1991. Molecular Aspects of Regeneration in the Spinal Cord, Division of Restorative Neurology

and Human Neurobiology, Baylor College of Medicine, March 1992. Intraspinal Sprouting of Primary Afferents After Spinal Cord Injury, The Institute for

Rehabilitation and Research, Houston, November 1992. Postnatal development of nociceptors requires nerve growth factor, 7th World Congress on

Pain, Paris, France, August, 1993. Endogenous and Exogenous Factors in Spinal Cord Regeneration, Elba Institute, Elba,

Italy, September, 1993. Transplantation and Growth Factors: Toward Recovery of Function, Conference on

Biomedical Engineering, Houston, February, 1996. Chronic Central Pain after Spinal Cord Injury, Conference on Biomedical Engineering,

Houston, February, 1996. Cellular Mechanisms of Recovery from Chronic Central Pain after Spinal Cord Injury,

Neurotrauma Society, Washington, D.C., November, 1996. Chronic Central Pain after Spinal Cord Injury, NIH Neurotrophin Group, Bethesda, MD, May

1997. Chronic Central Pain after Spinal Cord Injury, Mission Connect, November 1997. The Protean Nature of Pain: Central and Peripheral Mechanisms, Winter Conference On

Brain Res., January 1998. Chronic Central Pain after Spinal Cord Injury, Albuquerque, March 1998. Mechanisms of Chronic Central Pain after Spinal Cord Injury, Spring Pain Caymen, April,

1998. Chronic Central Pain after Spinal Cord Injury, Las Vegas, September 1998. D-Amphetamine Treatment: Mechanisms of Enhanced Recovery after Neocortical

Infarction, Behavior, Anatomy and Pharmacology, Eli Lilly Co., February, 1999. Autonomic Dysfunction after Spinal Cord Injury, FASEB, Vermont, July, 1999. Mechanisms of Perineal Pain in Spinal Cord Injury, International Association for the Study

of Pain (IASP), Vienna, Austria, August, 1999. Role of NMDA in Chronic Central Pain, Spring Pain Meetings, Caymen, April, 2000. Pathophysiological and Cellular Mechanisms in Spinal Cord Injury, Biomedical Engineering

Research, 19th Annual Meeting, Houston, Texas, February, 2001. From Concept to Clinic: Molecular Strategies for Behavioral Improvement after Spinal Cord

Injury, Miami Project, University of Miami, May, 2001. From Concept to Clinic: Molecular Strategies for Behavioral Improvement after Spinal Cord


Injury, The Institute for Rehabilitation and Research, Houston, Texas, September, 2001.

Dysfunctional Plasticity in Spinal Cord Injury: Central Neuropathic Pain, Int’l. Neurotrauma Society, Nov. 2002.

Recent Advances in the Pathophysiogy and Treatment of Spinal Cord Injury, Key Speaker, FASEB Meeting, New Orleans, 2002

Role of Metabotropic Glutamate Receptors in Chronic Central Pain, Spring Pain Meetings, Caymen, April, 2002.

Chronic Central Pain after Spinal Cord Injury, Houston, Texas, May 2002 Measuring Chronic Central Pain after Spinal Cord Injury, Univ. Calif. Irvine, July, 2002. Dysfunctional Plasticity in Spinal Cord Injury: Central Neuropathic Pain, Anesthesiology

Conf., Galveston, Tx, Jan. 2003 Dysfunctional Plasticity in Spinal Cord Injury: Central Neuropathic Pain, Univ. Calif. Irvine,

July, 2003. Chronic Central Pain after Spinal Cord Injury: Insights from DNA Microarray Analyses,

Spring Pain Meetings, Caymen, April, 2002. Chronic Central Pain after Spinal Cord Injury: Insights from DNA Microarray Analyses, Univ.

Calif. Irvine, July, 2004 Institute for Neurological Recovery, UTMB Presidents Council, 2003, 2004, 2005 Translational Research for Bladder and Bowel Recovery, Mission Connect, Jan. 2004 Potential Therapies to Treat Chronic Central Pain after Spinal Cord Injury, National

Academies of Sciences, Washington, D.C., May, 2004. Disproving the Edwin Smith Papyrus: Treatments for Spinal Cord Injury, Ohio State, Recruit

for Poppleton Chair, Nov. 2004 Disproving the Edwin Smith Papyrus: Treatments for Spinal Cord Injury, University of

Pennsylvania, Dec. 2004 Disproving the Edwin Smith Papyrus: Treatments for Spinal Cord Injury, University of Puerto

Rico, Feb. 2005 Novel Treatments for Central Neuropathic Pain Syndromes, UTMB Combined Conference,

April, 2005. Treatments for Spinal Cord Injury: Disproving the Edwin Smith Papyrus, Sell Lecturer, Key

Note Speaker, American Spinal Injury Association (ASIA), May, 2005. Mechanisms of Chronic Central Pain after Spinal Cord Injury, 2005 Frontiers in Spinal Cord

Regeneration Symposium, Louisville, KY, June, 2005. Chronic Pain after Spinal Cord Injury Reversed by Transplantation of Engineered Stem

Cells, 24th Annual Houston Conference on Biomedical Engineering Research, Houston, TX, February, 2007.

Mission Connect: Recovery from Central Nervous System Injury, Neurosciences Research Retreat, Memorial Hermann – Texas Medical Center, Houston, TX, May, 2007.

MAP Kinases and the Transcription Factor CREB in Central Neuropathic Pain after Spinal Cord Injury or Persistent Pain is a Cellular Memory, American Spinal Injury Association (ASIA) 33rd Annual Scientific Meeting, Tampa, FL, May 31 – June 2, 2007.

Gliopathy Contributes to Persistent Inflammation and Dysfunction after CNS Trauma. International Neurotrauma Symposium, Santa Barbara, CA, Sept. 11, 2009.

Inflammation and Persistent Pain after Spinal Cord Trauma. Rutgers University, South Plainsfield, NJ, November, 2010.

Inflammation and Persistent Pain after Spinal Cord Trauma. Uniformed Services University of the Health Sciences, Bethesda, Maryland, January, 2011.


Gliopathy Contributes to Persistent Inflammation and Dysfunction after CNS Trauma. Bluegrass Society for Neuroscience Symposium, University of Kentucky, Lexington, KY, March 31, 2011.

Gliopathy Contributes to Persistent Inflammation and Dysfunction after CNS Trauma. Current Advances in Spinal Cord Injury Research Symposium, University of Medicine and Dentistry of New Jersey Medical School, Newark, NJ, May 11, 2011.

Blood Brain and Blood Spinal Cord Barrier: Fact or Fiction? Neurotrauma Symposium Speaker, Phoenix, AZ, July 23, 2012

Inflammation and Persistent Pain after Spinal Cord Trauma. University of Miami, Miami Project, Miami, Fl, January 6-7, 2014

Chronic Pain After Spinal Cord Injury, Chair; National Neurotrauma Society, San Francisco, CA, June, 2014

Pain After SCI: Plasticity, Activity and Treatment, Chair-National Neurotrauma Society, Snowbird, Utah, July, 2017.

PROFESSIONAL REFERENCES: Dr. Richard E. Coggeshall, M.D. Professor Department of Neuroscience and Cell Biology University of Texas Medical Branch at Galveston 301 University Boulevard Galveston, Texas 77555-1069 E-mail: [email protected] Jin Mo Chung, Ph.D. Professor and Chairman Department of Neuroscience and Cell Biology University of Texas Medical Branch Galveston, TX 77555-0625 Tel: (409) 772-2171/6708 (Work) Tel: (409) 771-0713 (Cell) E-mail: [email protected] Regino Perez-Polo, Ph.D. Professor, Chairman Department of Biochemistry and Molecular Biology University of Texas Medical Branch at Galveston 301 University Boulevard Galveston, Texas 77555 E-mail: [email protected] Oswald (Ossie) Steward, Ph.D.

mailto:[email protected]

https://urldefense.proofpoint.com/v2/url?u=http-3A__mailto-3Ajmchung-40utmb.edu&d=AAMFAg&c=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ&r=7YxPQI-yLmLWO6GXgynrHc3L0RBWzUAYBnV8s2TTARU&m=H_-_3Acy5kMrKznpOryuSGa4ZwH1rXRb2tIoMX7HVLY&s=nVhFpNGTtu1PysnKQ387R38ofO7uLTWWheK8kZt2oAI&e=



Professor Director, Reeve-Irvine Research Center Anatomy & Neurobiology School of Medicine University of California 1105 GNRF Mail Code: 4292 Irvine, CA 92697 Phone: (949) 824-8908 Fax: (949) 824-2625 E-mail: [email protected] John Povlishock, Ph.D. Professor and Chairman Anatomy and Neurobiology Sanger Hall, 12-050 P.O. Box: 980709 Richmond, VA 23298 Phone: 804-828-9623 Fax: 804-828-9477 E-mail: [email protected] W. Dalton Dietrich, Ph.D. Professor Director of the Miami Project to Cure Paralysis 1095 NW 14th Terrace Locator Code R-48 Miami, Florida 33136 Tel: 305-243-8182 FAX: (305) 243-3913 E-mail: [email protected]




Documents

Curriculum Vitae March, 2019 Claire E. Hulsebosch, Ph.D. · Curriculum Vitae . March, 2019 . Claire E. Hulsebosch, Ph.D. PRESENT TITLE: Adjunct Professor of Neurobiology and Anatomy