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Curriculum Vitae : James A. Carson

Table of Contents Background Education ……………………………………………………… Page 2 Professional Service ……………………………………………………… Page 3 Employment History ……………………………………………………… Page 4 Publications Peer Reviewed Publications ……………………………………………………… Page 5 Literature Reviews / Book Chapters ……………………………………………………… Page 11 Presented Abstracts ……………………………………………………… Page 12 Student Mentorship High School Research ……………………………………………………… Page 16 Undergraduate Fellows ……………………………………………………… Page 18 Awards: High School & Undergraduate ……………………………………………………… Page 19 Chair Undergraduate Honors Thesis ……………………………………………………… Page 20 Mentored Undergraduate Programs ……………………………………………………… Page 21 Doctoral Student Supervision ……………………………………………………… Page 22 Masters Student Supervision ……………………………………………………… Page 24 Mentored Graduate Fellowships & Grants ……………………………………………………… Page 25 Mentored Graduate Awards ……………………………………………………… Page 26 Research Grants Pending / Active ……………………………………………………… Page 27 Completed Grant Funding ……………………………………………………… Page 28 Submissions not funded ……………………………………………………… Page 32 Presentations Research ……………………………………………………… Page 33 Instructional / Professional ……………………………………………………… Page 38 Teaching Recent Courses Taught ……………………………………………………… Page 40 Courses Developed ……………………………………………………… Page 41 Service University ……………………………………………………… Page 43 School of Public Health / Department ……………………………………………………… Page 43 Professional / Community ……………………………………………………… Page 45 Certifications ……………………………………………………… Page 46

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Curriculum Vitae James A. Carson

Professor

Chair, Exercise Science Department

Director, The Integrated Muscle Biology Laboratory Department of Exercise Science Arnold School of Public Health University of South Carolina Public Health Research Center, Rm. 301, 921 Assembly Street, Columbia SC 29208 Phone: Office: (803) 777-0809; Lab: (803) 777-0142 carsonj@mailbox.sc.edu

Education

B.S. 1985 Business Administration, Insurance and Risk Management, The Ohio State University, Columbus. Ohio

Ph.D. 1993 Exercise Science, College of Education, The Ohio State University, Columbus. Stephen E. Alway, Ph.D., Advisor; Dissertation Title: The effect of aging on fiber number and satellite cell activation in the

anterior latissimus dorsi muscle of the Japanese quail after stretch overload.

Attended the University of Akron, Master of Business Administration (M.B.A) Graduate Program 1986. Completed 6 hours of graded coursework related Organizational Behavior & Management. Left the program to attend Graduate School at Ohio State.

Professional Training Post-Doctoral Research Fellow, 1993 - 1997. Dept. of Integrative Biology, Pharmacology, and Physiology, University of Texas Medical School, Houston. Principal Investigator: Frank Booth Ph.D. NRSA NIH Post-

Doctoral Fellowship Awarded to James Carson: Skeletal -actin promoter function during hypertrophy. Post-Doctoral Research Fellow, 1997 – 1999. Huffington Aging Center / Department of Cell Biology, Baylor College of Medicine, Houston TX. Principal Investigator: Robert J. Schwartz. Ph.D.

Professional Memberships

Delta Omega Society – Honorary Society in Public health American College of Sports Medicine (ACSM) American Physiological Society (APS) National Strength & Conditioning Association (NSCA) Society on Sarcopenia, Cachexia, & Wasting Disorders (SCWD)

Awards • USC Educational Foundation Award for Research in Health Sciences, 2017. Campus-wide award for outstanding

research in Health Sciences

• Distinguished Research Leadership Award, South Carolina Governor’s School for Science and Mathematics, 2016. Recognition for successful mentoring of high school student summer research.

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• Delta Omega Society – Mu Chapter, Inducted into the Honorary Society in Public Health, 2015

• “STAR” Reviewer Award for Excellence in Peer Review for 2011 – American Physiological Society

• Arnold School of Public Health Faculty Research Award, for excellence in health research, 2009

• ACSM Fellow status (FACSM), awarded 2008, American College of Sports Medicine

• Nominated for the Arnold School of Public Health Keith Teaching Award, 2004, 2009, 2012, 2013.

• Nominated for the University of South Carolina Key Award for Integrating Undergraduate Teaching and Research, 2007.

• Varsity letter Football, The Ohio State University, 1981, 1982, 1983 o Linemen of the week, Ohio State vs. Illinois, 1982; Ironman Award Ohio State Football Fall 1982

Professional Service Professional Organizations • American College of Sports Medicine Research Advisory Committee, 2006 – 2009

• American College of Sports Medicine Science Integration & Leadership, Committee. 2009 – 12

• Nominated to run for ACSM Board of Trustees election (not elected), 2013

• Co-chair 2014 ACSM/APS Integrative Exercise Meeting, Appointed, 2013 - 14

• Exercise Physiology Councilor, Environmental & Exercise Section, American Physiological Society. Elected 2012 –15.

• Muscle Biology Steering Committee, American Physiological Society, Appointed. 2012 – 2016

• Executive Board, Southeast Chapter of American College of Sports Medicine (ACSM). Elected 2014 – 2016

• Diversity & Leadership Training Program, American College of Sports Medicine. 2013 – 2016

• Diversity Committee, American Kinesiology Association, 2018 - present

Editorial Duties • Editorial Board, Exercise & Sports Science Reviews, American College of Sports Medicine. 2011 – 2014

• Editorial Board, American Journal of Physiology Integrative & Regulatory. 2009 – 2015

• Editorial Board, Journal of Applied Physiology, 1999 – 2002; 2013 – 2017

• Associate Editor, Medicine & Science in Sports & Exercise (MSSE) 2017 – present.

• Associate Editor, Journal of Cachexia, Sarcopenia and Muscle (JCSM), Gender Research basic, 2018 - present Grant Review • Mid Atlantic American Heart Association Grant Review Committee: Molecular Signaling, 2003 - 2005

• World Cancer Research Fund (WCRF) research grant Ad Hoc review, 2011

• French Muscular Dystrophy Association (AFM) Grant Review, 2011

• NASA Grant Review Panel: Muscle Study Section, 2012, Radiobiology March 2017

• Veterans Affairs Cellular & Molecular Medicine Grant Review Panel Member, 2013 – 2016

• Michael Smith Foundation for Health Sciences, British Columbia, reviewer, April 2014

• NIH SMEP Study Section external reviewer, June 2014, October 2014, June 2017

• NIH/NCI Provocative Questions: Cancer Therapies and Outcomes, reviewer, March 2013, October 2014

• NIH/NCI Tumor Biology Study Section, external reviewer, June 2015, Feb. 2017, Oct 2017, June 2018

• NIH/CSR Fellowship Review Panel Vascular & Hematology IRG, Physiology and Pathobiology of Musculoskeletal, Oral, and Skin Systems. October 2015, July 2016, April 2018

University Service (selected) • Search Committee member, Director of Cardiovascular Disease Translational Research Center, USC School of

Medicine 2017-2018

• University-wide NIH Fellowships Advisor, USC Fellowships & Scholar Programs, 2013 – Present

• Faculty advisor for Exercise Science Majors Club Student Organization, 2013 – Present.

• Faculty advisor for South Carolina Club Lacrosse Student Organization. 2104 - Present

• University SC VP Research Aspire-I Review Committee, 2014

• Integrated Biomedical Sciences Graduate Program Steering Committee. Appointed. 2010 – 2016

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• Judge for the Junior Science & Humanities Symposium. 2010, 2011, 2012, 2014, 2015, 2016, 2017

• University Athletics Advisory Committee. ELECTED, 3-year term , 2013 – 2016.

• Faculty advisor for South Carolina Club Football Student Organization. 2010 – 2014.

• University Committee on Tenure and Promotion (UCTP). ELECTED, 3-year term, served 1. 2013 – 2014.

• Animal Care Users Group. Appointed. University-wide committee, 2010 – 2014.

• Institutional Animal Use and Care Committee, President appointed. 2001 through 2009. Other Service (selected) • Doctoral Program Review Committee, University of Houston, October 2017

• External Doctoral Dissertation reviewer and committee member, York University, Toronto, Ayesha Saleem, 2013

• Diversity mentor ACSM National Meeting 2013 & 2014, PhD student Bridget Peters, Auburn University,

• APS Frontiers in Physiology Professional Development Mentor, Betsy Scarborough, Middle School Teacher Richland 1 School District Columbia SC, 2004

Employment Chair, Exercise Science Department, University of South Carolina. October 2014 - Present Associate Director, The Center for Colon Cancer Research at the University of South Carolina. 2013 – 2018

Interim Chair, Exercise Science Department, University of South Carolina. August – September 2014

Professor, Exercise Science, Arnold School of Public Health, University of South Carolina. 2011 – Present Director, Graduate Studies for Exercise Science, U. of South Carolina. 2007 – 2014 Associate Professor (with Tenure), Exercise Science, Arnold School of Public Health, U. of South Carolina, 2005 – 11

Division Head, Division of Applied Physiology, Exercise Science Department, U. of South Carolina, 2004 - 08

Assistant Professor (Tenure Track), Exercise Science, Arnold School of Public Health, U. of South Carolina, 1999 – 05

Post-Doctoral Research Fellow, Cell Biology/Huffington Aging Center, Baylor College of Medicine, Houston 1997 – 99

Post-Doctoral Research Fellow Physiology and Cell Biology Dept., U. Texas Medical School, Houston. 1993 - 97

Graduate Research Assistant, Exercise Science, The Ohio State University, Columbus Ohio. 1991 – 93

Graduate Teaching Assistant, Exercise Physiology, The Ohio State University, Columbus, Ohio. 1989-91

Graduate Assistant Coach, Strength & Conditioning Varsity football, men’s & women’s basketball, and ice hockey.

The Ohio State University Athletic Department, Columbus, OH., 1987 - 89

Management, Yellow Freight Inc., Cleveland, Ohio, 1985 - 87

Personal Statement: My "Integrative Muscle Biology Laboratory" employs molecular biology techniques with in vivo and in vitro models examining muscle plasticity. We have been examining the regulation of muscle wasting with cancer cachexia. We are examining the importance of muscle metabolic capacity on protein turnover and apoptosis regulation during initial and severe stages of wasting.

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Scholarship: Peer-Reviewed Publications

J Carson Google Scholar: (see link) Current h-index 44; 10-index: 81; Citations: 4,920 (04/09/2018) J Carson SCOPUS Author ID: 7201381039, h-index 36; 3,519 citations (04/09/2018)

J Carson PubMed ORCID ID: orcid.org/0000-0003-3733-8796

15 articles cited over 100 times

* denotes mentorship: USC student or post-doc author contribution (italics direct J. Carson supervision) + denotes leadership: corresponding author / senior author $ BOLD reference: highly cited article (over 100 citations) Published / In Press: Citations Google Scholar, journal impact factor is 5 yr. at the year published

2018 98. Hardee, J.P.*, DK Fix*, X Wang, EC Goldsmith, HJ Koh BR Counts*, S. Gao*, B.N. Vanderveen*, H.J. Koh, and Carson J.A+. Systemic IL-6 regulation of eccentric contraction-induced muscle protein synthesis. Am J Physiol Cell Physiol (APS Journal). In Press 2018 Impact factor 3.6 (5 yr.) 97. Hardee, J.P.*, BR Counts*, S. Gao*, B.N. Vanderveen*, DK Fix*, HJ Koh, and JA Carson+. Inflammatory Signaling Regulates Eccentric Contraction-induced Protein Synthesis in Cachectic Skeletal Muscle. J. Cachexia Sarcopenia & Muscle. 20182018; 9(2):369-383. PMCID: PMC5879978 Impact factor 9.6 (2016) 96. Fix D.K.*, JP Hardee*, S Gao*, BN VanderVeen*, KT Velazquez*, and JA Carson+. The Role of gp130 in Basal and Exercise Trained Skeletal Muscle Mitochondrial Quality Control. J. Appl. Physiol. (APS Journal) In press 2018

Impact factor 3.5 (5 yr) 95. Vanderveen B.N.*, JP Hardee*, DK Fix*, and JA Carson+. Skeletal Muscle Function During the Progression of Cancer Cachexia in the Male ApcMIN Mouse. J. Appl. Physiol. (APS Journal) In press 2018 Impact factor 3.5 (5 yr)

94. Bader JE, Enos RT, Velázquez KT, Carson MS, Nagarkatti M, Nagarkatti PS, Chatzistamou I, Davis JM, Carson JA, Robinson C, and EA Murphy. Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer. Am J Physiol Gastrointestinal Liver Physiol 2017 (APS Journal) 2018;314(1):G22-G31. PMCID: PMC5866374 Impact factor 3.8 (5 yr.)

93. Kaur K, A Saxena, I Debnath, JL O'Brien, NJ Ajami, TA Auchtung, JF Petrosino, AJ Sougiannis, S Depaep, A Chumanevich, PM Gummadidala, MH Omebeyinje, S Banerjee, I Chatzistamou, P Chakraborty, R Fayad, FG Berger, JA Carson, and A Chanda. Antibiotic-mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression. Cancer Medicine. In press 2018; Impact factor 2.9 (2015)

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92. Gao, S*., JL Durstine, HJ Koh, WE Carver, N Frizzell, and JA Carson+. Acute myotube protein synthesis regulation by IL-6 related cytokines. Am J Physiol Cell Physiol (APS Journal). 2017; 313(5):C487-C500.PMCID: PMC5792171 Impact factor 3.6 (5 yr.) 91. Hetzler,K.L.*, JP Hardee*, HA LaVoie, EA Murphy, and JA Carson+. Ovarian Function’s Role During Cancer Cachexia Progression in the Female Mouse. American J Physiol. Endocrine Metab. (APS Journal), 2017; 312(5):E447-E459. PMCID: PMC5451525 Impact factor 4.3 (5yr)

90. Brown, J.L., ME Rosa-Caldwell, DE Lee, TA Blackwell, LA Brown, RA Perry, WS Hayne, JP Hardee*, JA Carson, M.P. Wiggs, TA Washington, and NP Greene. Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumor bearing mice. J. Cachexia Sarcopenia & Muscle. 2017; 8(6):926-938 PMCID: PMC5700433 Impact factor 9.6 (2016) 89. Chandrashekaran V, Seth RK, Dattaroy D, Alhasson F, Ziolenka J, Carson J, Berger FG, Kalyanaraman B, Diehl AM, Chatterjee S. HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease. Redox biology. 13:8-19, 2017. PMCID: PMC5447385 Impact Factor 6.3 (5yr)

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88. Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader JE, Sougiannis AT, Pritchett C, Fan D, Carson JA, Murphy EA. Mi155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice. Physiol Rep. 2017 Sep;5(18). (In Press) 87. Choi RH, McConahay A, Jeong HW, McClellan JL, Hardee JP*, Carson JA, Hirshman MF, Goodyear LJ, Koh HJ. Tribbles 3 regulates protein turnover in mouse skeletal muscle. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1236-1242. Impact factor 2.4 (5 yr.) 86. Saxena A, R Fayad, K Kaur*, S. Truman, J. Greer, JA Carson, and A. Chanda. Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer. Cancer Biology and Therapy, 2017 Apr 3;18(4):257-267 2017. PMCID: PMC5450735 Impact factor 3.1 (5yr) 85. Bonetto A., JK Kays, VA Parker, R Matthews, R Barreto, M Puppa*, KS Kang, JA Carson, T Guise, K S Mohammad, A Robling, M Couch, L Koniaris, TA Zimmers. Differential bone loss in mouse models of colon cancer cachexia. Frontiers in Physiology, Jan 11;7:679 2017 PMCID: PMC5225588 Impact factor 4.0 (2016) 84. Brown, JL, ME Rose-Caldwell, DR Lee, LA Brown, RA Perry, KL Shimkus, TA Blackwell, JD Fluckey, J A Carson, S

Dridi, and NP Greene. PGC-14 gene expression is suppressed by the IL-6-MEK-ERK ½ MAPK signaling axis and altered by resistance exercise, obesity, and muscle injury. Acta Physiologica Jun;220(2):275-288 2017 Impact factor 4.3 (2015) 2016 83. Fix, DK*, JP Hardee*, TA Bateman, and JA Carson+. The Effect of Irradiation on AKT Phosphorylation During Skeletal Muscle Disuse Atrophy. J. Appl. Physiol. (APS Journal) 2016 Oct 1;121(4):917-924 PMCID: PMC5142305 Impact

factor 3.42 (5 yr) 82. Velzquez, KY*, RT Enos, MS Carson, TL Cranford, JE Bader, I Chatzistamou, UP Singh, PS Nagarkatti, M Nagarkatti, JM Davis, JA Carson, and EA Murphy. Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model. American J Physiol. GI & Liver (APS Journal) 2016 Oct 1;311(4):G699-G712. PMCID: PMC5142197 Impact factor 3.30 (5 yr) 81. Narsale AA*, MJ Puppa*, J. Hardee*, BN Vanderveen*, RT Enos, EA Murphy and, JA Carson+. Short-term pyrrrolidine dithiocarbabate administration attenuates cachexia-induced alterations to muscle and liver in ApcMIN mice. Ocotarget Sep 13;7(37):59482-59502 2016. PMCID:PMCC5312326 Impact factor 6.37 (5 yr.) 80. Mangum, JE*, JP Hardee*, DK Fix*, MJ Puppa*, J Elkes, D Altomare, Y Bykhovskaya, DR Campagna, P. Schmidt, AK Sendamarai, HGW Lidov, S Barlow, N Fischel-Ghodsian, M D Fleming, JA Carson, and Jeffrey R. Patton. Pseudouridine synthase 1 deficient mice, a model for Mitochondrial Myopathy with Sideroblastic Anemia, exhibit muscle morphology and physiology alterations. Scientific Reports (NPG) May 20;6:202 2016 PMCID: PMC4873756 Impact factor 5.57 (2015) 79. Gao S*, and J.A. Carson+. Lewis Lung Carcinoma Regulation of Mechanical Stretch–Induced Protein Synthesis in Cultured Myotubes. Am J. Physiol. Cell Physiol. (APS Journal) 1;310(1)C66-79 2016 PMCID: PMC4698448 - Impact factor 3.94 (5yr.) 78. Hardee, J.P.*, J.E. Mangum*, S. Gao, S. Sato*, K.L. Hetzler*, M.J. Puppa*, D.K. Fix*, and J.A. Carson+. Eccentric Contraction-Induced Myofiber Growth in Tumor-Bearing Mice. J. Appl Physiol (APS Journal) 1:120(1):29-37 2016 PMCID: PMC4698440 - Impact factor 3.77 (5yr.) 2015 & earlier 77. Hetzler, K.L.*, J.P. Hardee*, M.J. Puppa*, A.A. Narsale , S. Sato*, J.M. Davis, and J.A. Carson+. Sex Differences in the Relationship of IL-6 Signaling to Cancer Cachexia Progression. Biochemica Biophysica Acta: Molecular Basis for Disease. 1852(5):816-25 2015. PMCID: PMC4372501. - Impact factor 4.97 (5 yr) 76. Narsale, A.A.*, R.T. Enos*, M.J. Puppa*, S. Chatterjee, E.A. Murphy, R. Fayad, M.O., Pena, J.L. Durstine, and J.A. Carson+. Liver Inflammation and metabolic Signaling in ApcMin/+ mice: The role of cachexia progression. PLOS One 015 Mar 19;10(3):e0119888 PMCID: PMC4366213 – Impact Factor 3.70 (5 yr) 75. Puppa, M.J.*, S. Gao*, A.A. Narsale*, and J.A. Carson+. Skeletal Muscle glycoprotein 130s role in Lewis Lung carcinoma-induced cachexia. FASEB Journal 28(2):998-1009 2014. PMCID: PMC3898653 - impact factor 6.22 (5 yr) 20

citations 74. Velazquez, K.T.*, R.T. Enos*, A. Narsale*, M.J. Puppa*, J.M. Davis, E.A. Murphy, and J.A. Carson+. Quercetin supplementation attenuates the progression of cancer cachexia via IL-6/STAT3 signaling pathway. J Nutrition 144(6):868-75 2014. PMCID: PMC4018949 - Impact factor 4.693 (5 yr) 11 citations

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73. Hardee, J.P.*, C. Porter, L.S. Sidosis, J.A. Carson, D.N. Herndon, and O.E. Suman. The role of early rehabilitative exercise training in the recovery from pediatric burn. Med Sci. Sports Exercise 46(9):1710-6 2014. PMCID: PMC4122649 - impact factor 4.47( 5yr)

72. Puppa, M.J.*, E.A. Murphy, R Fayad, G.A. Hand, and J.A. Carson+. Cachectic Skeletal Muscle Response to a Novel Bout of Low Frequency Stimulation. J Appl. Physiol. 116(8):1078-87 2014. PMCID: PMC4035786 - impact factor 4.14 (5 yr) 71. Washington, T.A*, J.M. Healey*, R.W. Thompson*, L.L. Lowe, and J.A. Carson+. Lactate dehydrogenase regulation in aged skeletal muscle: Regulation by anabolic steroids and functional overload. Experimental Gerontology 57:66-74 2014. impact factor 3.80 (5 yr) 70. J. L. Steiner * , J. M. Davis, J.L. McClellan*, R.T. Enos, J.A. Carson, R. Fayad, M. Nagarkatti, P.S. Nagarkatti, D. Altomare , K.E. Creek, E.A. Murphy: Dose-dependent benefits of quercetin on tumorigenesis in the C3(1)/SV40Tag transgenic mouse model of breast cancer. Cancer Biol Ther. 2014 Nov 2;15(11):1456-67 - impact factor 3.33 (5 yr) 69. Hardee, J.P.*, Puppa, M.J.*, D.K. Fix*, S. Gao*, K.L. Hetzler*, T.A. Bateman, and J.A. Carson+. The Effect of Radiation Dose on Mouse Skeletal Muscle Remodeling. Radiation & Oncology 48(3):247-56 2014. PMCID: PMC4110081 impact factor 1.60 (2012) 11 citations 68. Gordon, B.S.*, .C. Delgado Diaz*, J. Carson, R. Fayad, L.B. Wilson, and M.C. Kostek. Resveratrol improves muscle function but not oxidative capacity in young mdx mice. Canadian J. of Physiology & Pharmacology 92(3):243-51. 2014 - impact factor 1.73 (5 yr) 13 Citations

67. White J.P.*, M.J. Puppa.*, Gao S.*, Sato S.*, S.L. Welle and J.A. Carson+. Muscle mTOR1 Suppression by IL-6 During Cancer Cachexia: A role for AMPK. American J Physiol. Endocrine Metab. 304(10): E1042-52 2013. PMCID: 3651620 - impact factor 4.83 (5 yr) 24 citations 66. Lima, M.*, S. Sato*, R.T. Enos*, J.W. Baynes, and J.A. Carson+. Development of an UPLC-mass spectrometry method for measurement of myofibrillar protein synthesis: application to analysis of murine muscles during cancer cachexia. J Applied Physiol. 114 (6): 824-828, 2013 PMCID 3615602 - impact factor 4.14 (5 yr) . 7 citations 65. White, J.P*. S Gao*, M.J. Puppa*, S. Sato*, S.L. Welle, and J.A. Carson+. Testosterone regulation of Akt/mTORC1/FOXO3a Signaling in Skeletal Muscle. Molecular & Cellular Endocrinology. 365(2): 174-186 2013. PMCID 3529800 - impact factor 3.35 (5 yr) 33 citations 64. White J.P.*, M.J. Puppa*, A.A. Narsale*, and J.A. Carson. Characterization of the male ApcMIN mouse as a hypogonadism

model related to cancer cachexia. Biology Open Dec 15;2(12):1346-53 2013. PMCID: PMC3863419 Impact Factor TBD 10 citations 63. Mannie, N.D.P.K., M. Lima*, R.T. Enos*, P. Wehner, J.A. Carson, and E. Blough. Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the Apc Min/+ mouse. International J. Oncology. 42(6): 2134-40, 2013 PMCID 23589074 - impact factor 2.80 (5 yr), 11 citations

62. Puppa M.J.*, J.P. White*, K. T. Velázquez*, K. A. Baltgalvis*, S. Sato*, J.W. Baynes & J.A. Carson+. The effect of exercise on IL-6 induced cachexia in the ApcMin/+ mouse. J Cachexia Sarcopenia & Muscle. Jun;3(2):117-37, 2012 PMCID: 3374019 2013 Impact factor 7.52 (5 yr.) 30 citations 61. White J.P.*, Puppa M.J.*, Sato S.*, Gao S.*, Price R.L., Baynes J.W., Kostek M.C., Matesic L, and J.A. Carson+. IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse. Skeletal Muscle. Jul 6:2:14, 2012 PMCID:3431229 Impact Factor 5.14 , 34 citations 60. Frizzell, N., S.A. Thomas*, J.A. Carson, J.W. Baynes. Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity. Biochem J. Jul 15;445(2):247-54, 2012 – impact factor 4.66 (5 yr.) 59. McClellan J.L.*, J. M. Davis, J. L. Steiner*, D Jung*, M. D. Carmichael, J. A. Carson, M. M. Pena, F. G. Berger and E. A. Murphy. Linking tumor associated macrophages, inflammation, and intestinal tumorigenesis: Role of MCP-1. Am J Physiol GI. 15:303(10): G1087-95 2012 - impact factor 3.62 (5 yr.), 21 Citations

58. Gordon. B, J.P. White*, J.A. Carson, and M.C. Kostek. Six1 and Six1 cofactor expression is altered during early skeletal muscle overload in mice" J. Physiological Sciences. Sep:62(5):393-401, 2012 – Impact factor 1.64 (5yr) 5 citations

57. White, J.P.*, John W. Baynes, Stephen L. Welle, Suichi Sato*, and J.A. Carson+. The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the ApcMin/+ Mouse. PLos ONE volume 6: issue 9 e24650 2011 PMCID: 3176277 64 citations 56. Puppa M.J.*, J.P. White*, S. Sato*, M. Cairns*, J.W. Baynes & J.A. Carson+. Gut barrier dysfunction in the ApcMin/+ mouse model of colon cancer cachexia. Role of gut barrier dysfunction. Biochemica Biophysica Acta: Molecular Basis for Disease. Dec;1812(12):1601-6 2011. PMCID: 3205242 36 citations

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55. Washington, T.A.*, J.P. White*, J. M. Davis, †L. B. Wilson, L. L. Lowe, & J.A. Carson +. Skeletal Muscle Mass Recovery from Atrophy in IL-6-/- Mice. Acta Physiologica (Oxf) Aug:202(4):657-69, 2011 PMCID: PMC3129379 42 citations 54. White, J.P.*, K.A. Baltgalvis*, M. Puppa*, S. Sato*, J.W. Baynes, and J.A. Carson+. Muscle oxidative capacity during IL-6 dependent cancer cachexia. Am J Physiol Regul Integr Comp Physiol. 300:R201-R211, 2011. PMCID: PMC3043802 58 citations 53. Baltglavis, K.A.*, F.G Berger, MM.O Pena, J.M. Davis, J.P. White*, and J.A. Carson* . Activity level, apoptosis and the development of cachexia in ApcMin/+ mice. J. Applied Physiol. 109(4):1155-61 2010 PMCID: PMC296332 27 citations 52. Carmichael, M.D., J.M. Davis, E.A. Murphy, J.A. Carson, N. Van Rooijen, E. Mayer, and A. Ghaffar. Role of brain macrophages on IL-1 beta and fatigue following eccentric exercise-induced muscle damage. Brain Behav Immun. 24(4):564-8, 2010. 30 citations 51. Liu, Huijie, S.E. Chen, B. Jin, J.A. Carson, A. Niu, W. Durham, J.Y. Lai, and Y.P. Li. TIMP:3: A physiological mediator of adult myogenensis. J. Cell Science 123:2914-21, 2010. PMCID: PMC2923569 38 citations 50. Baltgalvis, K.A.*, FG Berger, MMO Pena, JM Davis, and JA Carson+. The Interaction of a High-Fat Diet and Regular Moderate Intensity Exercise on Intestinal Polyp Development in ApcMin/+ Mice. Cancer Prevention Research. Jul :2(7):641-9, 2009. PMCID: PMC2886505 34 citations 49. White, J.P.*, K.A. Baltgalvis*, S Sato*, L Britt Wilson, and J.A. Carson+. The Effect of Nandrolone Decanoate Administration on Recovery from Bupivacaine-induced Muscle Injury. Journal of Applied Physiology 107:1420-1430, 2009. PMCID: PMC2777803 36 citations 48. White, J.P *, J. M. Reecy, T.A. Washington*, S. Sato*, J.M Davis, L.B Wilson, and J.A. Carson+. Overload-induces skeletal muscle exracellular matrix remodeling and myofire growth in mice lacking IL-6. Acta Physiologica 197:321-332, 2009. PMCID: PMC3044433 18 citations 47. Frizzell, N, M Rajesh, MJ Jepson, R Nagai, JA Carson, SR Thorpe, and JW Baynes. Succination of thiol groups in adipose tissue proteins in diabetes: Succination inhibits polymerization and secretion of adiponectin. Journal of Biological Chemistry 284(38):25772-25781 2009. PMCID: PMC2757979 62 citations 46. Bandstra E.R, R.W. Thompson,* G.A. Nelson, S. Judex, M.A. Cairns,* E.R. Benton, J.S. Willey, M.E. Vazquez, J.A. Carson, and Ted A. Bateman. Musculoskeletal Changes in Mice from 20–50 cGy of Simulated Galactic Cosmic Rays. Radiation Research . 172, 21-39 2009. 23 citations 45. Baltgalvis, K.A.*, FG Berger, MMO Pena, JM Davis, JP White*, and JA Carson+. Muscle wasting and Interleukin-6-induced atrogin-I expression I in the cachectic APC Min/+ mouse. Pflugers Arch (Euro J Physiol). Mar;457(5):989-1001. 2009 PMCID: PMC2867110 43 citations $44. Baltgalvis KA*, FG Berger, MMO Pena, JM Davis, SJ Muga, and JA Carson+. Interleukin-6 and Cachexia in ApcMin/+ Mice. Am J. Physiol. Regul Integr Comp Physiol 294(2):R393-401, 2008. 176 citations 43. Baltgalvis KA*, F.G. Berger, M.M. Pena, J.M. Davis, J.M McClung*, and J.A. Carson+. The effect of exercise on biological pathways in ApcMin/+ mouse intestinal polyps. J. Appl. Physiol. 104(4):1137-1143, 2008. 32 citations 42. Murphy, E.A., J.M., A.S. Brown, M.D. Carmichael, J.A. Carson, van Rooijen N., A. Ghaffar, and E.P. Mayer. Benefits of oat(beta)-glucan on respiratory infection following exercise stress: role of lung macrophages. Am J Physiol Integr. Comp Physiol. 294(5):R1593-9, 2008. 29 citations 41. McClung J.*, J.M. Davis, and J.A. Carson+. Ovarian Hormone Status and Skeletal Muscle Inflammation during Recovery from Disuse. Experimental Physiology, 92.1 219-232, 2007. 31 citations 40. Brown AS, J.M. Davis, E.A. Murphy, M.D. Carmichael, J.A. Carson, A. Ghaffar, and E.P Mayer. Susceptibility to HSV-1 infection and exercise stress in female mice: role of estrogen. J Appl Physiol. Nov;103(5):1592-7 2007. 9 citations 39. Stanfel, M.N, K.A. Moses, J.A. Carson, D.B. Zimmer, F. DeMayo, R.J. Schwartz, and W.E. Zimmer. Expression of an Nkx3.11-CRE gene using ROSAA26 reporter mice. Genesis 44(11):550-5, 2006. 10 citations 38. Carmichael, M.D., J.M. Davis, E.A. Murphy, J.A. Carson, E. Mayer, and A. Gahaffar. Role of brain IL-1B on fatigue following exercise-induced muscle damage. Am J. Physiol. Regul Integr Comp Physiol 291:R1344-R1348, 2006. 61 citations 37. Thompson R.W. *, Joseph M. McClung*, Kristen A. Baltgalvis*, J. Mark Davis, and James A. Carson+, Modulation of Overload-Induced Inflammation by Aging and Anabolic Steroid Administration. Experimental Gerontology 41:1136-1148, 2006. 34 citations $36. McClung J.*, J.M. Davis, M.E. Wilson, E.C. Goldsmith, and J.A. Carson+. Estrogen status and skeletal muscle recovery from disuse atrophy. Journal of Applied Physiol. 100(6):2012-23 2006. 105 citations

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35. Brown, A.S., J.M. Davis+, E.A. Murphy, M.D. Carmichael, J.A. Carson, A. Ghaffar, and E.P. Mayer. Gender differences in macrophage antiviral function following exercise stress. Med. Sci. Sports Exerc. 38(5):859-863, 2006. 13 citations $34. Alderson, N.L., W. Yuping, M. Blatnik, N. Frizzell, M.D. Walla, T.J. Lyons, N. Alt, J.A. Carson, R. Nagai, S.R. Thorpe, and J.W. Baynes+. S-(2-succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate. Arch Biochem Biophys 450(1):1-8, 2006. 101 citations 33. Mehl, K.A*., J.M. Davis, F.G. Berger, and J.A. Carson+. Myofiber Degeneration / Regeneration is induced in the cachectic ApcMIN/+ mouse. Journal of Applied Physiol. 99:2379-2387 2005. 40 citations 32. Mehl, K.A*., J.M. Davis, J.M. Clements*, F.G. Berger, M. Pena, and J.A. Carson+. Decreased intestinal polyp multiplicity with exercise is dependent on intensity, gender, and inflammatory state in ApcMIN/+ mice. Journal of Applied Physiology 98:2219-2225, 2005. 70 citations 31. McClung J.*, K. Mehl*, R.W. Thompson*, L.L. Lowe, and J.A. Carson+. Nandrolone Decanoate modulates initial overload induced changes in muscle morphology and gene expression in rat soleus muscle. Am J Physiol Regul Integr Comp Physiol . 288:R1543-R1552, 2005. 28 citations 30. Carmichael, M.D.*, J.M. Davis+, E.A. Murphy*, A.S. Brown*, J.A. Carson, E. Mayer, and A. Ghaffar. Recovery of running performance following muscle damaging exercise: Relationship to brain IL-1β. Brain, Behavior, & Immunity, 19(5):445-52, 2005. 40 citations $29. Neiman, D.C., J.M. Davis, D.A. Henson, S.J. Gross, C.L. Dumke, A.C. Utter, D.M. Vinci, J.A. Carson, A. Brown*, SR McAnulty, LS McAnulty, and NT Triplett. Muscle cytokine mRNA changes after 2.5h of cycling: influence of carbohydrate. Med Sci Sports Exerc. 37(8):1283-90, 2005. 131 citations 28. Washington, T.A.*, J.M. Reecy, R.W. Thompson*, L.L. Lowe, J.M. McClung*, and J.A. Carson+. Lactate Dehydrogenase Expression at the Onset of Altered Loading in Rat Soleus Muscle. J. Appl. Physiol. 97:1424-1430, 2004. 15 citations 27. Alt N.*, J.A. Carson, N.L. Alderson, R. Nagai, T. Henle, S.R. Thorpe, and J.W. Baynes+. Muscle protein is protected from chemical modification in diabetic rats. Archiv Biochem & Biophys 425: 200-206, 2004. 61 citations 26. McClung J.*, R.W. Thompson*, L.L. Lowe, and J.A. Carson+. RhoA expression during recovery from skeletal muscle disuse. J. Appl. Physiol. Apr;96(4): 1341-8, 2004. 19 citations $25. Neiman, D.C., J.M. Davis, V.A. Brown, D.A. Henson, C.L. Dumke, A.C. Utter, D.M. Vinci, M.F. Downs, J.C. Smith, J.A. Carson, A. Brown*, S.R. McAnulty and L.S. McAnulty. Carbohydrate and immunity following resistance training. J. Appl. Physiol. Apr;96(4):1292-8, 2004. 157 citations 24. Carson, J.A.+, D.E. Culberson, R.W. Thompson*, R.A. Fillmore, and W.E. Zimmer. Smooth muscle -actin promoter regulation by RhoA and serum response factor signaling. Biochimica et Biophysica Acta, Jul 28;1628(2):133-9, 2003. 8 citations 23. McClung, J.*, W.J. Lee*, R.W. Thompson*, L.L. Lowe, and J.A. Carson+. RhoA induction by functional overload and nandrolone decanoate administration in rat skeletal muscle. European J. Physiol.; Pflugers Archiv. Dec;447(3):345-55, 2003. 25 citations 22. Lee, W.J.*, J. McClung*, R.W. Thompson*, and J. A. Carson+. Regulation of Androgen Receptor Expression at the onset of functional overload in rat plantaris muscle. AM J Physiol Regul Integr Comp Physiol . Nov;285(5):R1076-85. 2003. 42 citations 21. Lee, W.J.*, J. McClung*, G.A. Hand, and J. A. Carson+. Overload-induced androgen receptor expression in the aged rat hindlimb receiving nandrolone decanoate. J. Appl. Physiol. 94:1153-1161, 2003. 41 citations 20. McClung, J.*, G. Hand, J.M. Davis, and J.A. Carson+. Effect of creatine supplementation on the cardiac muscle of endurance trained rats. Euro. J. Appl. Physiol. 89:26-33 2003. 11 citations $19. Nieman, D.C., J.M. Davis, D.A. Henson, J. Walberg-Rankin, M. Shute, C.L. Dumke, A.C. Utter, D.M. Vinci, J.A. Carson, A. Brown*, W.J. Lee*, S.R. McAnulty, and L.S. McAnulty. Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run. J. Appl. Physiol. 94:1917-1925, 2003. 333 citations 18. Carson, J.A.+, W.J. Lee*, J. McClung*, and G.A. Hand. Steroid Receptor Concentration in aged rat hindlimb muscle: The effect of anabolic steroid administration. J. Appl. Physiol. 93:242-250, 2002. 53 citations 17. Hand, G, C. Hewitt, L. Fulk,* H. Stock, J.A. Carson, J. Davis, and M. Wilson. Differential release of corticotropin-releasing hormone (CRH) in the amygdala during different types of stretch. Brain Research 949:122-130, 2002. 43 citations $16. Carson, JA, D. Nettleton, and J.M. Reecy. Differential gene expression in the rat soleus muscle during early work overload-induced hypertrophy. FASEB J 16(2):207-209, 2002. 121 citations 15. Wei, L., L. Wang, J.A. Carson, J.E. Agan, K.I. Yoshida, and R.J. Schwartz. 1 integrin and organized actin filaments facilitates

cardiomyocyte specific RhoA-dependent activation of the skeletal -actin promoter. FASEB J. 15:785-796 2001. 65 citations

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$14. Carson, J.A., R. A. Fillmore, R.J. Schwartz, and W.E. Zimmer. The smooth muscle gamma-actin gene promoter is a molecular target for mNkx 3.-1 , a vertebrate homologue of Drosophila Bagpipe, and serum response factor. J. Biol. Chem. 275(50):39061-39072, 2000. 102 citations $13. Fluck, M., J.A. Carson, A. Ziemieki, and F.W. Booth. Focal adhesion proteins FAK and paxillin increase with overload-induced hypertrophy of ALD muscle. Am J. Physiol. 277(46):C152-C162, 1999. 127 citations 12. Fluck, Martin, J.A. Carson, R.J. Schwartz, and F.W. Booth. SRF protein is up-regulated during stretch-induced hypertrophy of rooster ALD muscle. J. Appl. Physiol. 86(6):1793-1799, 1999. 50 citations 11. Carson, J.A., and F.W. Booth. Serum response factor mRNA induction in the hypertrophying chicken patagialis muscle. J. Appl. Physiol. 86(1): 377-382 1999. 16 citations 10. Carson, J.A., and F.W. Booth. Effect of serum and mechanical stretch on skeletal -actin gene regulation in cultured primary myocytes. Am. J. Physiol. (Cell Physiol. 44): C1438-1448, 1998. 45 citations 9. Carson, J.A., and F.W. Booth. Myogenin mRNA is elevated during rapid-, slow-, and maintenance-phases of stretch-induced hypertrophy. Pflugers Arch- Eur. J. Physiol. 435:850-858, 1998. 44 citations 8. Marsh, D.R., J.A. Carson, L.N. Stewart, and F.W. Booth. Activation of the skeletal -actin promoter during muscle regeneration. J. Muscle Res. & Cell Mot. 19(8):897-907, 1998. 18 citations $7. Marsh, D.R., D.S. Criswell, J.A. Carson, W.T. Lester, and F.W. Booth. Myogenic regulatory factors during regeneration of skeletal muscle in young, adult, and old rats. J. Appl. Physiol. 83(4): 1270-1275, 1997. 143 citations 6. Carson, J.A., R.J. Schwartz and F.W. Booth. SRF and TEF-1 regulation of the skeletal -actin promoter during stretch overload induced hypertrophy in slow tonic muscle of young chickens. Am. J. Physiol. (Cell 39) 270:C1624-C1633, 1996. 92 citations 5. Carson, J.A., and S.E. Alway. Stretch overload-induced satellite cell activation in slow tonic muscle from adult and aged Japanese quail. Am. J. Physiol. (Cell 39) 270:C578-C584, 1996. 54 citations 4. Carson, J.A., M. Yamaguchi and S.E. Alway. The time course of adaptations to stretch-overload in the aged Japanese quail. J. Gerontology 50(6):B391-398, 1995. 20 citations 3. Carson, J. A., Z. Yan, F. W. Booth, M.E. Coleman, R. J. Schwartz, and C.S. Stump. Regulation of the skeletal -actin promoter in young chickens during hypertrophy caused by stretch overload. Am. J. Physiol. (Cell 37): C918-C924, 1995. 64 citations 2. Alway, S.E., J.A. Carson and W.J. Roman. Adaptation in myosin expression of avian skeletal muscle after weighting and unweighting. J. Muscle Res. & Cell Mot. 16:111-122, 1995. 9 citations 1. Carson, J.A., M. Yamaguchi. and S.E. Alway. Hypertrophy and proliferation of skeletal muscle fibers from aged quail. J. Appl. Physiol. 78(1): 293-299,. 1995. 36 citations

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Scholarship: Refereed Literature Reviews / Book Chapters * denotes USC mentored student author contribution (italics direct J. Carson supervision) + denotes corresponding author / senior author $ BOLD reference: highly cited article (over 100 citations)

Refereed Review of Literature Publications 2018 14. Hardee JP*, Counts BR*, Carson JA+. Understanding the Role of Exercise in Cancer Cachexia Therapy. American Journal of Lifestyle Medicine. In press 2018. (invited, refereed) 2017 13. Hardee JP*, RN Montalvo*, and JA Carson+. Linking Cancer Cachexia-Induced Anabolic Resistance to Skeletal Muscle Oxidative Metabolism. Oxidative Medicine and Cellular Longevity. 2017; 2017:8018197. PMCID: PMC5742498 (invited, refereed) 12. VanderVeen, B.N*., D.K. Fix*, and J.A. Carson+. Disrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis During Cancer Cachexia: A Role for Inflammation. Oxidative Medicine and Cellular Longevity. 2017; 2017:3292087. PMCID: PMC5530417 (invited, refereed) Impact factor 4.49 (2015)

11. Hardee, J.P.*, and J.A. Carson+. Understanding Sarcopenia Development: A Role for Healthy Behaviors. American Journal of Lifestyle Medicine. January 2017 Vol 11 (1) 17-20, 2017. (invited, refereed) 2016 & earlier 10. Carson, J.A.+, J.P. Hardee*, & B.N. VanderVeen*. Skeletal muscle oxidative metabolism’s emerging role as a biological target and cellular regulator of cancer –induced muscle wasting. Seminars –Cell and Dev. Biol. Jun;54:53-57 2016 (invited refereed) PMCID: PMC487246, impact factor – 6.21 (5 yr). 17 citations

9. Carson, J.A. & S.C. Manolagas. Effects of sex steroids on bones and muscles: similarities, parallels, and putative interactions in health and disease. Bone Nov;80:67-78. 2015 PMCID: PMC4600533 (invited, refereed) impact factor 4.31 (5 yr). 21 citations

8. Narsale AA*, & J.A. Carson+. Role of interleukin-6 in cachexia: therapeutic implications. Curr Opin Support Palliat Care. 2014 Dec;8(4):321-7, 2014. PMCID: PMC4323347 (invited, refereed) 2014 impact factor 1.66 44 citations $7. Carson J.A.+ & K. Baltgalvis*. Interleukin 6 as a key regulator of muscle mass with cancer cachexia. Exercise & Sports Science Reviews, 38:4 168-176, October 2010. (invited, refereed) PMCID: PMC3065300 122 citations $6. Dudgeon, W.D.*, Phillips K.D., Carson J.A., Brewer R.B., Durstine J.L., and G.A. Hand+: Counteracting muscle wasting in HIV-infected individuals. HIV Medicine (7):299-310, 2006. 100 citations 5. A. Pinasco* & J.A. Carson+. Preseason conditioning for college soccer players. Strength and Conditioning Journal, National Strength & Conditioning Association 27(5):56-65, 2005. $4. Carson, J.A.+, and L. Wei. Integrin Signalling: A potential role in overload-induced hypertrophy. J. Appl. Physiol. 88:337-343, 2000. (invited, refereed) 137 citations $3. Booth, F.W., B.S. Tseng, M. Fluck, and J.A. Carson. Molecular and cellular adaptation of muscle in response to physical training. Acta Physiol. Scand. 162:343-350, 1998. 142 citations 2. Carson, J.A.+. The regulation of Gene Expression in Hypertrophying Skeletal Muscle. (ed) J.O. Holloszy. Exercise and Sports Science Reviews. Balt. MD. Williams & Wilkins. pg 301-320, 1997. (invited, refereed) 45 citations 1. Criswell, D.S., J.A. Carson, and F.W. Booth. Regulation of contractile protein gene expression in unloaded mouse skeletal muscle. J. Gravitational Physiol. 3(2):58-60, 1996. 5 citations

Book Chapters J.A. Carson & M. Puppa*. Biological Pathways Impacting Cancer Survival: Exercise as a countermeasure for the development and progression of cachexia. (eds) C. Ulrich, K Steindorf, N Berger. Exercise, Energy Balance and Cancer. Series: Energy Balance and Cancer 2012 J. Baynes & J.A Carson. Muscle: Energy Metabolism and Contraction. (ed) J. Baynes & M.H. Dominiczak. Medical Biochemistry, Mosby 2009. J. Baynes & J.A Carson. Muscle: Energy Metabolism and Contraction. (ed) J. Baynes & M.H. Dominiczak. Medical Biochemistry, Mosby 2004. Carson, J.A., and F.W. Booth. Molecular biology of exercise. (ed) W.E. Garrett. Textbook of Sports Medicine (Vol. I). Media, PA. Williams & Wilkins. 2000. Booth F.W., J.A. Carson and Z.. Yan. Molecular and cellular adaptations of muscle in response to exercise. (eds) R.J. Maughan and S.M. Shirreffs. Biochemistry of Exercise IX. Champaign, IL. Human Kinetics. pg 339-344, 1996

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Scholarship: Presented / Published Abstracts 2018 Counts BR, VanderVeen BN, Hardee JP, Fix DK, Montalvo RN, Carson JA. Cancer Environments Effect on Skeletal Muscle mTORC1

Regulation by Physical Activity and Feeding in Mice. ACSM National Conference, Minneapolis, Minnesota. May 2018. VanderVeen BN, Fix DK, Counts BR, Carson JA. The Regulation of Skeletal Muscle Function by Muscle gp130 Signaling. Federation of

American Societies for Experimental Biology (FASEB) National Meeting. San Diego, CA. April 2018 Fix DK, VanderVeen BN, Hardee JP, and Carson JA. Muscle DRP-1 and FIS-1 Regulation by IL-6 Signaling. Federation of American Societies

for Experimental Biology (FASEB) National Meeting. San Diego, CA. April 2018. Counts BR, VanderVeen BN, Hardee JP, Fix DK, Carson JA. Diurnal Regulation of Skeletal Muscle Anabolic Signaling Through mTORC1.

SEACSM 2018. Chattanooga, TN. Saunders LA, Counts BR, VanderVeen BN, Hardee JP, Fix DK, Montalvo RN, Carson JA. Diurnal Variations in Female Tumor Bearing Mice.

SEACSM 2018. Chattanooga, TN. Blalock JL, VanderVeen BV, Fix DK, Carson JA. The Relationship Between Skeletal Muscle Function and Structural Alterations in Cancer

Cachexia. SEACSM 2018. Chattanooga, TN. Kaura NK, VanderVeen BV, Fix DK, Counts BR, Hardee JP, Carson JC. Muscle Akt Signaling Sensitivity to Short-Term Fasting in Tumor

Bearing Mice. SEACSM 2018. Chattanooga, TN.

2017 Counts BR, Laresen KM, VanderVeen BN, Hardee JP, Fix DA, Minaya MK, Davis C, Pena MM, Carson JA. 5-Fluoroucil’s Effect on Indices of Skeletal

Muscle Wasting in ApcMin/+ Mouse. Sarcopenia, Cachexia, and Muscle Wasting Conference, December 2017 Rome, Italy. Counts BR, Fix DA, Hardee JP, Carson JA. Relationship between muscle oxidative metabolism and ribosomal capacity: effects of exercise and gp130

loss. ACSM National Conference. Denver, Colorado. May 2017. VanderVeen BN, Hardee JP, Fix DK, Gao S, Carson JA. Muscle Inflammatory Signaling's Contribution to Cancer Cachexia-induced

Decrements in Muscle Function. FASEB/ APS National Meeting. Chicago, IL. April 2017. Fix DK, Hardee JP, Gao S, VanderVeen BN and Carson JA. Muscle gp130 Receptor Regulation of Oxidative Metabolism During Cancer

Cachexia. FASEB / APS National Meeting. Chicago, IL. April 2017. Gao S, and Carson JA. Short term Regulation of myotube protein synthesis by IL-6 related cytokines. FASEB /APS National Meeting.

Chicago, IL. April 2017. Hardee JP, Gao S, VanderVeen BN, Fix DK, and Carson JA. Inflammatory Signaling Regulation of Eccentric Contraction–induced Muscle

Protein Synthesis in Cachectic Skeletal Muscle. Federation of American Societies for Experimental Biology (FASEB) National Meeting. Chicago, IL. April 2017.

VanderVeen BN, Fix DK, Hardee JP, Mangum J, Gao S, Carson JA. A Novel Slow-Fatigable Skeletal Muscle Phenotype Develops During the Progression of Cachexia. Advances in Skeletal Muscle Biology in Health and Disease Conference. Gainesville, FL. March 2017.

Fix DK, Hardee JP, Gao S, VanderVeen BN and Carson JA. gp130 Regulation of Muscle Mitochondrial Dynamics During Cancer Cachexia. Advances in Skeletal Muscle Biology in Health and Disease Conference. Gainesville, FL. March 2017.

Gao S, and Carson JA. Short term Regulation of myotube protein synthesis by IL-6 related cytokines. Advances in Skeletal Muscle Biology in Health and Disease Conference. Gainesville, FL. March 2017.

Hardee JP, Gao S, VanderVeen BN, Fix DK, and Carson JA. Inflammatory signaling regulation of eccentric contraction-induced protein synthesis in cachectic skeletal muscle. Advances in Skeletal Muscle Biology in Health and Disease Conference. Gainesville, FL. March 2017.

Choi RH, McConahay A, Hardee JP, Carson JA, Hirshman MF, Goodyear LJ, Koh HJ. “TRB3 Regulates Protein Turnover in Mouse Skeletal Muscle” 2017 Advances In Skeletal Muscle Biology in Health and Disease, University of Florida, Gainesville, FL

Hardee JP, Gao S, VanderVeen BN, Fix DK, and Carson JA. Muscle protein synthesis regulation by eccentric contractions during cancer cachexia. Southeast American College of Sports Medicines (SEACSM) Annual Conference. Greenville, SC. February 2017.

Counts BR, Hardee JP, Carson JA. Muscle Ribosomal Capacity in Tumor Bearing Mice. Southeast American College of Sports Medicines (SEACSM) Annual Conference. Greenville, SC. February 2017.

Dennis K. Fix, Justin P. Hardee, Song Gao, Brandon N. VanderVeen, James A. Carson. “The Role of gp130 in the Regulation of Muscle Mitochondrial Dynamics During Cancer Cachexia”. Center for Colon Cancer Research. Annual Retreat, Columbia SC, 2017.

2010- 2016 Hardee JP, Gao S, VanderVeen BN, Fix DK, and Carson JA. Eccentric contraction regulation of mTORC1 signaling in cachectic skeletal

muscle. 9th Internal Cachexia, Sarcopenia and Wasting Disorders Conference. Berlin, Germany, December 2016 Fix, Dennis K., Justin P. Hardee, Song Gao, Brandon N. VanderVeen, James A. Carson. Muscle Oxidative Metabolism Regulation by gp130

Signaling During Cancer Cachexia. 3rd Cancer Cachexia Conference, Washington DC, 2016. Gao S, and Carson JA. Cytokines IL-6 and LIF can differentially regulate myotube protein synthesis. 3rd Cancer Cachexia Conference.

Washington DC. September 2016. VanderVeen BN, Hardee JP, Fix DK, Gao S, and Carson JA. The Relationship between Skeletal Muscle Function and Inflammation during

the Progression of Cancer Cachexia. 3rd Cancer Cachexia Conference. Washington DC. September 2016. Hardee JP, Gao S, VanderVeen BN, Fix DK, and Carson JA. Eccentric contraction regulation of mTORC1 signaling in cachectic skeletal

muscle. 3rd Cancer Cachexia Conference. Washington, DC. September 2016. Gao S and Carson JA. Role of gp130 in basal and mechanical stretch induced myotube protein synthesis. Federation of American

Societies for Experimental Biology (FASEB) National Meeting. San Diego, CA. April 2016. Fix, Dennis K. , J. P. Hardee, S. Gao, B. N. VanderVeen, J. A. Carson. Exercise Training Induced Regulation of Muscle Mitochondrial

Dynamics. Federation of American Societies for Experimental Biology (FASEB) National Meeting, San Diego, CA. April 2016.

13

Hardee JP, Gao S, VanderVeen BN, Fix DK, Hetzler KL, and Carson JA. Mouse cachectic skeletal mTORC1 signaling in response to acute eccentric contractions. Federation of American Societies for Experimental Biology (FASEB) National Meeting. San Diego, CA. April 2016.

Gao S. and J A. Carson. Basal and Stretch-induced Myotube Protein Synthesis Regulation by gp130 Signaling. Advances in Skeletal Muscle Biology in Health and Disease Conference, Gainesville, FL, 2016.

JP Hardee, S Gao, DK Fix, BN VanderVeen, KL Hetzler, and JA Carson. Cachectic mouse skeletal muscle anabolic response to acute and training eccentric contractions. Advances in Skeletal Muscle Biology in Health and Disease Conference, Gainesville, FL, 2016.

Fix Dennis K., Justin P. Hardee, Song Gao, Kimbell L. Hetzler, JA. Carson. The Role of gp130 in the Regulation of Muscle Mitochondrial

Dynamics with Cancer Cachexia. Center for Colon Cancer Research Retreat, Columbia, SC, 2016. Hardee JP, Gao S, Fix DK, VanderVeen BN, Hetzler KL, and JA Carson. Cachectic mouse skeletal muscle anabolic response to acute and

training eccentric contractions. 8th International Conference on Cachexia, Sarcopenia and Muscle Wasting. Paris, France. December 2015.

Hardee JP, Mangum JE, Fix DK, Sato S, Puppa MJ, Hetzler KL , and JA Carson. Cachectic skeletal muscle response to eccentric and concentric contractions. ACSM National Meeting, San Diego CA. May 2015

Gao S, and Carson JA. Lewis Lung Carcinoma Regulation of Mechanical Stretch–Induced Protein Synthesis in Cultured Myotubes. Experimental Biology, April 2015. Boston, MA.

LA Brown, JL Brown, ME Rosa, DE Lee, RA Perry Jr, JP Hardee, JA Carson, NP Greene and TA Washington. Progression of Cancer Cachexia Alters Muscle Lactate Metabolism in ApcMin/+ Mice. Experimental Biology, April 2015. Boston MA

Hetzler KL, Hardee JP, Puppa MJ, Narsale AA, Sato S, Davis JM, Carson JA. IL-6 Signaling during cancer cachexia progression: The female response Experimental Biology, April 2015. Boston MA 29(1 Supplement ):1038.11

Hardee JP, Gao S, Hetzler KL, Sato S, Puppa MJ, and Carson JA. Stat3 regulation in cachectic skeletal muscle after repeated eccentric contractions. Experimental Biology, April 2015. Boston MA

Hardee JP, Mangum JE, Fix DK, Sato S, Puppa MJ, Hetzler KL, and Carson JA. Cachectic skeletal muscle response to eccentric and concentric contractions: a role for stat3 signaling. American College of Sports Medicine Conference, Southeast Chapter, February 2015. Jacksonville FL

Hetzler KL, Carson JA. Effects of ovarian function on cancer cachexia progression. University of South Carolina Women's Health Research Forum, October 2014.

Puppa, MJ., Narsale, AA., Carson, JA., Role of IL-6 Trans-Signaling on Muscle Protein Synthesis During Cancer Induced Cachexia. Experimental Biology, Apr, 2014, San Diego, CA.

Hardee JP, Porter C, Sidossis LS, Carson JA, Herndon DN, and Suman OE. Effect of Early and Late Outpatient Exercise Training on Muscle Mass and Protein Kinetics in Severely Burned Children. Experimental Biology. April 2014. San Diego, CA.

Narsale, AA., Enos R., Puppa, MJ., Carson, JA., Liver Protein Synthesis and Glycogen Storage with the Progression of Cancer Cachexia, Experimental Biology, Apr, 2014, San Diego, CA.

Gao S, and Carson JA. Lewis lung carcinoma cells regulation of stretch-induced mTOR activation in C2C12 myotubes. Experimental Biology. April 2014. San Diego, CA.

Hetzler KL, Sato S, Narsale AA, Puppa MJ, Carson JA. The Effect of Sex on IL-6 Regulation of Cancer Cachexia Progression in the Apc min/+ mouse. Experimental Biology. April 2014. San Diego, CA.

Mangum JE, Hardee JP, Puppa MJ, Carson JA. The Effect of Cachectic Myofiber Metabolic Properties on the Resistance Exercise-Induced Hypertrophy Response. Experimental Biology. April 2014. San Diego, CA.

Hetzler KL, Carson JA. Sex Differences in Response to IL-6 during the Progression of Cancer Cachexia. University of South Carolina Graduate Student Day. April 2014. Columbia, SC.

Augustine MR, Hardee JP, Bateman TA, and Carson JA. The Effect of Unloading and Irradiation on Skeletal Muscle Protein Turnover. USC Discovery Day. April 2014. Columbia, SC.

Learner EL, Puppa MJ , Hardee JP, Hetzler KL, and Carson JA. The role of the skeletal muscle gp130 receptor in IL-6 induced muscle morphological changes. Discovery Day. April 2014. Columbia, SC.

Durante, E., Narsale, AA., Carson, JA., The Effect of Antibiotic Treatment on Liver Function in the ApcMin/+ mouse model of Cancer Cachexia, Discovery Day, April 2014, Columbia, SC

Simmons M., Narsale, AA, Carson JA, Role of IL-6 Signaling on Skeletal Muscle Wasting in the Female Lewis Lung Carcinoma Model of Cachexia, Discovery Day, Apr. 2014, Columbia, SC.

Hardee JP, Porter C, Sidossis LS, Carson JA, Herndon DN, and Suman OE. Effect of early outpatient exercise training on skeletal muscle mass and function in severely burned children. American Burn Assoc. March 2014. Boston, MA.

Yang JH, Narsale AA, Aartun, JD Puppa, MJ, and, Carson JA. The Effect of Antibiotic treatment on Liver function during Cancer Cachexia. College of Engineering and Computing, U South Carolina and SC Governor’s School for Science and Mathematics, Columbia SC July 2013

Schreiner M., Puppa M, Narsale A, McClellan J, Reagan L, Carson J. The effect of leptin receptor antagonist administration on rat skeletal muscle metabolic gene regulation. U South Carolina and SC Governor’s School for Science and Mathematics, Columbia SC July 2013.

Hardee JP, Puppa MJ, Narsale AA, Gao S, and Carson JA. The Effect of Cachexia Severity and Resistance Exercise on Skeletal Muscle Mass. American College of Sports Medicine. May 2013. Indianapolis, IN.

M.J. Puppa, J.A. Carson. Cachectic skeletal muscle response to a novel bout of low frequency stimulation. American College of Sports Medicine. May 2013. Indianapolis, IN.

Puppa MJ, Narsale AN, Gao S, Carson JA. Skeletal muscle gp130 receptor regulation of cancer cachexia-induced muscle mass loss. Experimental Biology. April 2013 Boston, MA.

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Gao S, Carson JA. Role of Trans-signaling Molecules from Lewis Lung Carcinoma (LLC) Cells on C2C12 Myotube Atrophy and Protein Turnover Regulation. Experimental Biology. April 2013 Boston, MA.

Puppa MJ, Narsale AN, Gao S, Carson JA. Skeletal muscle gp130 receptor regulation of cancer cachexia-induced muscle mass loss. St. Jude National Graduate Student Symposium. March 2013 Memphis, TN.

Puppa M.J., and J.A. Carson. Cachectic skeletal muscle response to a novel bout of low frequency stimulation. American College of Sports Medicine Conference, Southeast Chapter. Greenville SC Feb 2013.

Hardee JP, Puppa MJ, Narsale AA, Gao S, and Carson JA. The Effect of Cachexia Severity and Resistance Exercise on Skeletal Muscle Mass American College of Sports Medicine Conference, Southeast Chapter. Greenville SC Feb 2013.

Engel A., Velazquez K. , Narsale A., Puppa M.J., J.A. Carson. The effect of il-6 loss on initial ladder climbing exercise-induced changes in strength and muscle mass. American College of Sports Medicine Conference, Southeast Chapter. Greenville SC Feb 2013.

Hardee JP, Puppa MJ, Sato S, Carson WO, Hetzler KL, Bateman T, and J.A. Carson. The Effect of Radiation Dosing on Mouse Skeletal Muscle Oxidative Metabolism. American Society for Gravitational & Space. New Orleans, November 2012

Sato, S., M.J. Puppa, S. Gao, and J.A. Carson. The effect of muscle contraction on cachectic muscle mTOR signaling and protein synthesis in ApcMin/+ mouse. American Physiological Societ / Integrative Physiology of Exercise Meeting, Denver CO, October 2012.

Puppa M.J, J.P. White, S. Sato, S. Gao, and J.A. Carson. The effect of exercise training on anabolic responses in IL-6-induced cancer cachexia. Cancer Cachexia Conference Molecular Mechanisms and Therapeutic Approaches. Boston September 2012.

Carson WO, Hardee JP and Carson JA. The effect of radiation dosage on mouse skeletal muscle oxidative capacity. College of Engineering and Computing, University of South Carolina and SC Governor’s School for Science and Mathematics, Columbia SC July 2012.

White C., Puppa M.J., McClellan J., and J.A. Carson. The effects of quercetin on skeletal muscle protein degradation and oxidative capacity in mice afflicted with chemically induced cancer cachexia . Summer Programs for Research Interns. College of Engineering and Computing, University of South Carolina and SC Governor’s School for Science and Mathematics, Columbia SC July 2012.

Puppa M.J., J.P. White, S. Sato, and J.A. Carson IL-6 signaling regulates muscle FIS1 expression during the progression of cachexia. Advances in Skeletal Muscle Biology in Health & Disease Conference. Feb 2012

Sato S., M.J. Puppa, A.A. Narsale, A.D. Johannes, and J.A. Carson. The effect of resistance training on muscle maintenance in the ApcMin/+ mice. Advances in Skeletal Muscle Biology in Health and Disease, Gainsville, Florida. Feb 2012

Gao S., and J.A. Carson. Effects of different doses of IL-6 on pathways regulating protein turnover in C2C12 myotubes. Advances in Skeletal Muscle Biology in Health and Disease, Gainsville, Florida. Feb 2012

Puppa M.J., J.P. White, K.T. Velazquez, S. Sato, A.A Narsale, and J.A. Carson. Effect of exercise training on muscle energy status in IL-6 induced cachexia. American College of Sports Medicine Conference, Southeast Chapter. Jacksonville, FL. Feb 2012.

Velazquez K.T., J.P. Hardee, M.J. Puppa, J.D. Aartun, A.A. Narsale, S. Sato, J.M. Davis, and J.A. Carson. The Effect of Quercentin Supplementation on Volitional Fatigue and Skeletal Muscle Mass Retention During Cancer Cachexia. American College of Sports Medicine Conference, Southeast Chapter. Jacksonville, FL. Feb 2012.

Velazquez K.T., R.T. Enos, A. Narsale, J Aartun, M.J. Puppa, E.A. Murphy, M.J. Davis, J.A. Carson. Curcumin and quercetin supplementation attenuate lean body mass loss during the progression of cancer cachexia in the Lewis Lung Carcinoma-tumor-bearing mouse and ApcMin/+ mouse. 6th Cachexia Conference. Milan, Italy. Dec 2011.

White, JP., Sato, S, Puppa, M, Carson J. Exercise training prevents IL-6 suppression of muscle PGC-1α and Mitofusin 1 & 2 proteins during the progression of cachexia in the ApcMin/+ mouse. American Institute for Cancer Research Annual Research Conference, Washington DC (November 2011).

Sato S., M.J. Puppa, K.T. Velazquez, A. Narsale, J.P. White and J.A. Carson. The Effect Of Tumor Growth And Moderate Exercise On ApcMin/+ Mouse Cage Activity. National American College of Sports Medicine Meeting. Denver, CO. June 2011.

Puppa M.J., J White, K Velazquez, S Sato, J Aartun, J.A. Carson, Effect of exercise training on neuromuscular performance in cachectic mice. National American College of Sports Medicine Meeting. Denver, CO. June 2011.

Sato S., M. Lima, R. Enos, J.W. Baynes and J.A. Carson. The effect of oxidative capacity on mouse muscle protein synthesis during cachexia. Experimental Biology, Washington, D.C. April 2011.

White J.P, , M Puppa, S Sato, JBaynes, J.A, Carson. IL-6 inhibition attenuates activation of ubiquitin proteasome-dependent degradation in cachectic muscle. Experimental Biology, Washington, D.C. April 2011.

Narsale A.A, J D. Aartun, M J. Puppa, S Sato, J P. White, J W. Baynes and, J. A. Carson; The role of gut permeability and systemic bacterial load on cachexia progression in ApcMin/+ mice. Graduate Student Day, 8th April, 2011.

Puppa M.J., J.P. White, K. Velazquez, S. Sato, J. Aartun, J.A. Carson, Effect of exercise training on neuromuscular performance in cachectic mice. Southeast Region American College of Sports Medicine Meeting, Greenville SC. Feb 2011

White, J.P. Puppa MJ, Velazquez, KT, Baynes JW and J.A.Carson. Muscle protein Synthesis and IL-6-induced Cachexia in the ApcMin/+ Mouse. ACSM’s Conference on Integrative Physiology of Exercise endorsed by The American Physiological Society Miami, FL September 2010.

Anderson S.N., M.J. Puppa, White JP and J.A. Carson. The effect of exercise on skeletal muscle oxidative stress and mitochondrial biogenesis in ApcMin/+ mice. Summer Programs for Research Interns. College of Engineering and Computing, University of South Carolina and SC Governor’s School for Science and Mathematics, Columbia SC July 2010.

Sharperson, C.M., White JP, Puppa M., and J.A. Carson. The effects of exercise and fish oil supplementation on the development of anemia in a colorectal cancer mouse model. Summer Programs for Research Interns. College of Engineering and Computing, University of South Carolina and SC Governor’s School for Science and Mathematics, Columbia SC July 2010.

Pupa, M.J., J.P. White, K.T Velazquez, J.W. Baynes, and J.A. Carson, treadmill exercise and glucose clearance in ApcMin/+ mice. American College of Sports Medicine National Meeting, Baltimore MD, June 2010.

White, J.P. Puppa MJ, Velazquez, KT, Baynes JW and J.A.Carson. Treadmill Exercise and IL-6-induced Cachexia in the ApcMin/+ Mouse. American College of Sports Medicine. Baltimore, MD June 2010.

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White J.P., S. Sato, S.L. Welle and James A. Carson. The effect of castration on IGF-1 signaling and metabolic regulation in skeletal muscle. American Federation for Aging Research Grentee Meeting. Santa Barbara, CA June 2010.

White, J.P., Shuichi Sato, Melissa J. Puppa, John W. Baynes Stephen L. Welle and James A. Carson, IL-6-induced Cachexia and Muscle IGF-1 Signaling, Experimental Biology. Anaheim, CA. April 2010

Pupa, M.J., James P. White, Mark A. Cairns, Shuichi Sato, John W. Baynes, and James A. Carson, Role of gut barrier dysfunction and endotoxemia in development of colon cancer cachexia, Experimental Biology, Anaheim CA, April 2010. (2005.2)

Velazquez K.T., S Sato, JP White, MJ Puppa, JW Baynes, and JA Carson. Skeletal Muscle Oxidative Capacity in Cachectic Mice. Experimental Biology, Anaheim CA, April 2010 (283.11/II13)

White J.P., M.J. Puppa, S. Sato, J.W. Baynes and J.A. Carson. Glucose Tolerance and Exercise in a Mouse Model of Cancer Cachexia. American College of Sports Medicine Conference, Southeast Chapter Regional Meeting Greenville, SC. February 2010.

Sheehan J, White JP, Shuichi Sato and James Carson, The Association between Glucose Tolerance and Cachexia in the ApcMin/+ Mouse. American College of Sports Medicine, Southeast Chapter. Greenville, SC. February 2010.

2009 & earlier over 100 not shown

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Scholarship: Mentored High School Research

International Exchange High School Students 2017 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Graziella Veit, Schule School, Germany, German High School Exchange Student; Mentor: James A. Carson.

2016 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Jan Kunzmann, Schule School, Germany, German High School Exchange Student; Mentor: James A. Carson. 2015 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Luis Hauptmann , Johanna Wittum Schule School, Germany, German High School Exchange Student; Mentor: James A. Carson. 2015 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Nathalie Brucker , Johanna Wittum Schule School, Germany, German High School Exchange Student; Mentor: James A. Carson. 2014 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Hanna Meisi , Johanna Wittum Schule School, Germany, German High School Exchange Student; Mentor: James A. Carson. 2013 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Ines Mazurek, Johanna Wittum Schule School, Germany, German High School Exchange Student; Mentor: James A. Carson. 2013 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math.** Student: Jihoon Yang, Gyeonggi Science High School, Korean High School Exchange Student; Mentor: James A. Carson. 2012 South Carolina Fall Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. ** Student: Nicole Eger, German High School Exchange Student; Mentor: James A. Carson. 2012 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. ** Student: Enjoo Kang, Korean High School Exchange Student; Mentor: James A. Carson. South Carolina High School Students 2017 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Madeline DeCarlo, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2017 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: William Rumfelt, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2016 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Pierce Carrouth, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2016 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Matthew Re, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson 2015 International Baccalaureate Program Project, Dreher High School. Student: Jana Liese, Mentor: James A. Carson. 2015 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Emilia Baliou, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson.

2014 Dutch Fork High School Research Program, Student Olivia Reszcynski: Mentor James Carson,

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2014 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Nathan Pigone, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2014 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Mayank Patel, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson.

2013 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Jacqueline Budidharma, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2013 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Mathias Schreiner SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. Project

2012 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Cameron White, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2012 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: William Carson, Lexington High School; Mentor: James A. Carson. 2011 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Kyle Brennan, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2011 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Danielle Schwartz, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2010 – 2011 Daniel Miller, Richland Northeast High School, Magnate Honors Program Research Paper Research mentor/ community expert: James Carson 2010 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Camara Sharperson, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2010 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Samuel Anderson, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2009 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Grace Bradford, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2009 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Alex Kabil, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2008 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Sara Lancaster, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2007 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Victor Russo, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2007 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Chavis Stackhouse, Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2006 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Shobhit Vishnoi; Mentor: James A. Carson. 2005 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Bridgette Mobley, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson.

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2005 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Mary Beth Smith, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2003 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student: Alexis Demon, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson. 2002 South Carolina Summer Program for Research Interns. University of South Carolina Honors College & South Carolina Governor’s School for Science and Math. Student : Sean Tran, SC Governor’s School for Science & Mathematics; Mentor: James A. Carson.

Scholarship: Mentored Undergraduate Research Fellows Magellan Scholar Undergraduate Research Fellowship. University of South Carolina. Spring 2018 / Fall 2018, Student: Olivia Reszcynski , USC Biology Undergraduate. $2,500 stipend & supplies. Mentor: James A. Carson

Honors College Research Grant. University of South Carolina October 2017 – June 2018. Student: Jonathan Blalock, USC Exercise Science Undergraduate. $1580 stipend and supplies. Mentor: James A. Carson

Magellan Scholar Undergraduate Research Fellowship. University of South Carolina. Spring 2017/ Fall 2017, Student: Samantha Block, USC Exercise Science Undergraduate. $2,500 stipend & supplies. Mentor: James A. Carson Office of Undergraduate Research Mini Grant. University of South Carolina. Spring 2017. $750 stipend & Supplies. Student: Johnathon Blalock, USC Exercise Science Undergraduate. Mentor: James A. Carson Mentor: James A. Carson. Magellan Apprentice Capstone Scholar Fellowship. University of South Carolina. Fall 2015. Student: Sandra Block, USC Exercise Science Undergraduate Student. $999 stipend & Supplies. Mentor: James A. Carson Magellan Scholar Undergraduate Research Fellowship. University of South Carolina. Fall 2015/ Spring 2016, Student: Alison Saum, USC Exercise Science $3,000 stipend & supplies. Mentor: James A. Carson Magellan Scholar Undergraduate Research Fellowship. University of South Carolina. Summer/Fall 2013, Student: Matthew Augustine, USC Exercise Science Undergraduate $2,500 stipend & supplies. Mentor: James A. Carson Magellan Scholar Undergraduate Research Fellowship. University of South Carolina. Summer / Fall 2013, Student: Makiera Simmons, USC Biology Undergraduate $2,500 stipend & supplies. Mentor: James A. Carson Title:”. Honors College SURF Research Fellowship. University of South Carolina. Fall/Spring 2013, Student: Matthew Augustine, USC Exercise Science Undergraduate$2,500 stipend & supplies. Mentor: James A. Carson Honors College SURF Research Fellowship. University of South Carolina. Fall 2012-2013, Student: Elizabeth Durante, USC Biology & Dance Undergraduate, $3,000 stipend & Supplies. Mentor: James A. Carson Honors College SURF Research Fellowship. University of South Carolina. Fall 2012- 2013, Student: Emily Lerner, USC Exercise Science Undergraduate,$3,000 stipend & Supplies. Mentor: James A. Carson Title: “Muscle oxidative metabolism during the progression of Cancer” Honors College SURF Research Fellowship. University of South Carolina Student: Amber Engel, USC Exercise Science Undergraduate) $3,000 stipend & Supplies. Mentor: James A. Carson Title: “Muscle Contraction and Protein Synthesis with Cancer Cachexia” Honors College SURF Research Fellowship. University of South Carolina. Spring 2011 $3,000 stipend & Supplies. Student: Wesley Hardgrove (USC Exercise Science Undergraduate) Mentor: James A. Carson Title: “Exercise prevents muscle mass loss with cancer cachexia” Honors College Research Fellowship. University of South Carolina. 2009-2010$3,000 stipend & Supplies. Student: Aniruddh A Patel (USC Biology Undergraduate, currently in Medical School U of South Carolina School of Medicine) Mentor: James A. Carson Title: “Muscle mass loss with cachexia” Honors College Research Fellowship. University of South Carolina),.2008 – 2009 $3,000 stipend & Supplies. Student: Jewel Sheehan (USC Exercise Science Undergraduate, currently in Medical School U of North Carolina, Chapel Hill) Mentor: James A. Carson Title: “Muscle mass loss with cachexia” Honors College Research Project. University of South Carolina 2007. $1,000 expenses Student: Manish Dave (Senior, Biology Honors College. currently in Medical School Wake Forest University)

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Mentor: James A. Carson Title: “Effect of exercise and diet on ApcMin/+ mice intestinal apoptosis and COX-2 ”. Honors College Research Project. University of South Carolina 2007. $1,000 research expenses Student: Matt Jepson (Senior, Biology Honors College, currently in Medical School University of South Carolina School of Medicine) Mentor: James A. Carson Title: “Cachexia-induced heart extra-cellar matrix remodeling ”. Honors College Research Project. University of South Carolina 2007. $1,000 research expenses Student: Mike Kanwisher (Senior, Biology Honors College, currently in Medical School Medical College of Georgia) Mentor: James A. Carson Title: “Fish oil supplementation and cachectic muscle mass”. Honors College Research Fellowship. University of South Carolina 2006 - 2007. $3,000 stipend & Supplies. Student: Samantha Ingram (USC Biology Undergraduate) Mentor: James A. Carson Title: “Muscle mass loss with cachexia” Honors College Research Fellowship. University of South Carolina 2005 - 2006. $3,000 stipend;. Student Manish J. Dave (USC Biology Undergraduate) Mentor: James A. Carson Title: “The Effect of Exercise and a High Fat Diet on the Intestinal Polyp Incidence

Scholarship: AWARDS Mentored Research High School & Undergraduates 2017 Discover USC: Oral Presentation: U/P: Science, Technology, Engineering and Math First place, Olivia Reszczynski, Biochemistry and Molecular Biology, Economics – Sophomore. “The Role of Ovarian Function and Interleukin 6 in the Regulation of Muscle Oxidative Metabolism in Tumor Bearing Mice” 2017 Discover USC: Poster Presentation: U/P: Biology and Biomedical Sciences C First place, Jonathan Blalock, Exercise Science, Economics – Sophomore. “Cancer Cachexia-induced Disruption of the Skeletal Muscle Structure-Function Relationship” 2017 Discover USC: Poster Presentation: U/P: Biology and Biomedical Sciences B Second place-Tie, Samantha Block, Biological Sciences, Art Studio – Senior. Muscle inflammatory signaling regulation of cancer-induced mitochondrial dysfunction 2014 Discovery Day, University of South Carolina. April 2014. 2nd Place, Student Undergraduate Research Award Competition: Exercise Science & Physical Education. Mathew Augustine, Exercise Science, Honors College, University of South Carolina, Spring 2014 “ Radiation and disuse changes in skeletal muscle mTOR Regulation” (Carson Undergraduate Student). 2009 Discovery Day, University of South Carolina. April 2009. 1st Place, Student Undergraduate Research Award Competition: Biomedical Science Category. Student: Jewel Sheehan, Exercise Science, USC Honors College (Carson Undergraduate Student). The Association of Glucose Tolerance with Cachexia in the APCMin/+ .

2009 South Carolina Junior Academy of Science Competition, April 2009 1st Place - High School Written Science Project Paper: Biomedical Science Category. Student: Sarah Lancaster (Governors School of Science and Math, Summer Research position in Carson Lab). Submission titled “The Effect of Testosterone on Skeletal Muscle Mitochondrial Biogenesis and Apoptosis. 2008 Southeastern Chapter American College of Sports Medicine. Birmingham AL. 2nd Place - Student Research Award Competition Masters/Undergraduate Category. Student: Matt Jepson (Carson Undergraduate & Masters Student). Submission: The Effect of Cancer Cachexia on the Hypertrophying APCmin/+ Mouse Heart 2004 South Carolina Junior Academy of Science Competition, April 2004. 2nd place both Oral and Written High School Science Project Competition: Biomedical Science Category. Student: Alexis Deman (Governors School of Science and Math, Summer Research position in Carson Lab). Submission titled “Skeletal muscle wasting and associated gene expression in a mouse model of colon cancer.

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Scholarship: Chair of Undergraduate Honors Research Thesis Alex Teshon, Chemistry, Honors College, University of South Carolina, Spring 2016 James A. Carson chair

Emily Learner, Exercise Science, Honors College, University of South Carolina, Spring 2014 James A. Carson chair Mathew Augustine, Exercise Science, Honors College, University of South Carolina, Spring 2014 James A. Carson chair Elizabeth Durante, Biology & Dance, Honors College, University of South Carolina, Spring 2014 James A. Carson chair Andy Patel, Chemistry Major, Honors College, University of South Carolina, Spring 2010 James A. Carson chair Dave Manish, Biology major, Honors College, University of South Carolina, Spring 2007, James A. Carson chair Mike Kanwisher, Biology Honors College, University of South Carolina, Spring 2007, James A. Carson chair Mark Wilson, Exercise Science Honors College, University of South Carolina, Spring 2007, “ James A. Carson chair Matt Jepson, Biology Honors College, University of South Carolina Spring 2007, James A. Carson chair

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Scholarship: Mentored Undergraduate Research Programs 2017 Center for Colon Cancer Research Summer Research Experience for Minority Undergraduate Students. Student: Austin White , USC Public Health Undergraduate, Mentor: James A. Carson

2016 NSF funded South Carolina Alliance for Minority Participation in Research, Research experience for minority undergraduate students. Student: Deadrake Epps , USC Biology Undergraduate, Mentor: James A. Carson

2014 (Summer) NSF funded South Carolina Alliance for Minority Participation in Research, Research experience for minority undergraduate students. Student: Xavier Bell, Midlands Tech Undergraduate, Mentor: James A. Carson

2014, (Spring) Presbyterian College Program for Undergraduate Research, Students: Stephanie Dohmier. Devid Sellman, Floyd Nicholson. In conjunction with Presbyterian College faculty supplied biological samples and laboratory expertise to conduct 3 senior cancer research projects. 2009 University of South Carolina EXPORT Summer Research Internship Program, Research experience for minority undergraduate students. Student: Sonia Thomas, University of South Carolina, Biology Major, Mentor: James A. Carson Project titled: “Cachexia in the ApcMin/+ mouse: The role of Akt signaling”. 2008 USC School of Medicine Undergraduate Research Internship Program. Research experience for undergraduates Student: Loverica Irby, USC Biological Sciences Major, Mentor: James A. Carson Project titled: “Cancer cachexia and mitochondrial loss in skeletal muscle” 2008 University of South Carolina EXPORT Summer Research Internship Program, Research experience for minority undergraduate students. Student: Joseph Johnson, Claflin University Biology Major, Mentor: James A. Carson Project titled: “Intestinal GSK3-β phosphorylation in the ApcMin/+ mouse model of colorectal cancer”. 2008 University of South Carolina EXPORT Summer Research Internship Program, Research experience for minority undergraduate students. Student: Erica Littles, Claflin University Biology Major; Mentor: James A. Carson Project titled: “The effect of testosterone on skeletal muscle oxidative capacity”. Spring 2008 University of South Carolina Discovery Day, Research experience for USC undergraduate students. Student: Beth Wolf, USC Athletic Training Major; Mentor: James A. Carson Project: “MRSA incidence in a college volley ball environment”. Summer 2007 University of South Carolina EXPORT Summer Research Internship Program, Research experience for minority undergraduate students. Student: Mykenzi Gibbs, USC Exercise Science Major; Mentor: James A. Carson Project titled: “Akt activation during muscle regeneration”. Summer 2006 Palmetto Health – University of South Carolina Centers of Research Excellence Summer Biomedical Research Internship Program. Student: Puja Dalal, USC Exercise Science, USC Honors College. Mentor: James A. Carson. Project titled: “Androgen receptor expression in cachectic mouse muscle”. Summer 2005 Palmetto Health – University of South Carolina Centers of Research Excellence Summer Biomedical Research Internship Program. Student: Matt Jepson, USC Biology Major, USC Honors College. Mentor: James A. Carson. Project titled: “Effect of IL-6 on myosin expression in skeletal muscle during cachexia”. Summer 2004 Palmetto Health – University of South Carolina Centers of Research Excellence Summer Biomedical Research Internship Program. Student: Meagan Waltmann, USC Biology Major. Mentor: James A. Carson. Project titled: “Gene expression associated with intestinal polyp formation in the APCmin mouse”. Summer 2003 Palmetto Health – University of South Carolina Centers of Research Excellence Summer Biomedical Research Internship Program. Student: Emerson Gower III, USC Biology Major, USC Honors College. Mentor: James A. Carson. Project titled: “Cardiac hypertrophy and associated gene expression in a mouse model for colon cancer”. Summer 2002 Palmetto Health – University of South Carolina Centers of Research Excellence Summer Biomedical Research Internship Program. Student: Kristen Cook , USC Biology Major. Mentor: James A. Carson.

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Scholarship: Doctoral Student Supervision

Completed PhDs as Chair (13) 13. Justin Hardee, Fall 2017, Exercise Science, James Carson Chair Left to pursue: Post-Doctoral Research Fellowship, University of Melbourne, Australia PI: Dr. Gordon Lynch 12. Song Gao, Spring 2017, Exercise Science, James Carson Chair Left to pursue: Post-Doctoral Research Fellowship, University of Texas Medical School, Houston PI: Dr. Yi Ping Li 11. Kamaljeet Kaur, Spring 2016, Exercise Science, James Carson Chair Left to pursue: Post-Doctoral Research Fellow, University of Alabama Birmingham 10. Kimbell Hetzler, Fall 2015, Exercise Science, James Carson Chair Left to pursue: Post-Doctoral Research Fellow, Emory Medical School 9. Aditii Narsale, Spring 2014, Exercise Science Department, James Carson Chair Left to pursue: Post-Doctoral Research Fellow, Dept. Immunology, Penn State Medical School 8. Melissa Pupa, Fall 2013, Exercise Science Department, James Carson Chair Left ot pursue: Post Doctoral Fellow St. Judes Childrens Research Hospital, Memphis TN, Department of Developmental and Neurobiology, PI: Fabio Demontis 7. Suichi Sato , Summer 2012 , Exercise Science Department, James Carson Chair Left to Pursue: Post-doctoral Research Fellow, University of Louisville Medical School, Department of Anatomical Sciences and Neurobiology; PI: Dr. Ashok Kumar, 6. Kandy Velasquez, Summer 2012 , Exercise Science Department, James Carson Chair Left to Pursue: 2013 Post doctoral fellow USC School of Medicine

5. Jim White, Spring 2011, Exercise Science Department, James Carson Chair Left to Pursue: Post-doctoral Research Fellow, Dana-Farber Cancer Institute. Department of Cell Biology, Harvard Medical School; PI: Dr. Bruce Spiegelman 4. Tyrone Washington, Spring 2008, Exercise Science Department, James Carson Chair Left to Pursue: Tenure track faculty University of Evansville; 2011 - Current Tenure Track Assistant Professor, University of Arkansas

3. Ray Thompson, Summer 2007, Exercise Science Department, James Carson Chair Left to Pursue: Clinical Assistant Professor Faculty, University of South Carolina

2. Kristen Mehl-Baltgalvis, Summer 2007, Exercise Science Department, James Carson Chair Left to Pursue: Postdoctoral Fellow at University of Minnesota, Dr. Dawn Lowe PI; 2011 - Current Senior Scientist, Rigel Pharmaceuticals 1. Joseph McClung, Summer 2005, Exercise Science Department, James Carson chair Left to Pursue: Postdoctoral research Fellow at University of Florida, Scott Powers PI ;

External Dissertation reviewer: Ayiesha Saleem, York University ,Toronto Canada August 2013

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Completed PhDs as member of dissertation committee (10) Arpit Saxena, Spring 2015, Exercise Science Department, Raja Fayad, J Carson committee member. Jenny Stiener, Fall 2012, Exercise Science Department, Mark Davis, J Carson committee member. Brad Gordon, Spring 2012, Exercise Science Department, Matt Kostek, J Carson committee member.

Diana Delgado, Summer 2012, Exercise Science Department, Matt Kostek, J Carson committee member. Yin Xiong, Fall 2006, Biomedical Sciences Research Program, University of South Carolina School of Medicine. Bill Hrushesky chair. J Carson committee member.

Martin Carmichael , Fall 2005. Exercise Science Department, Mark Davis, J Carson committee member.

Adrian Brown, Spring 2004, , Exercise Science Department, Mark Davis, James Carson Committee member. Joel Atance, Spring 2004, Developmental Biology & Anatomy Department, University of South Carolina School of Medicine. Wayne Carver Chair, James Carson committee member. Angela Murphy, Summer 2004, Exercise Science Department, Mark Davis, J Carson committee member. Laura Fulk, Fall 2004, Exercise Science Department, Greg Hand, J Carson Committee member. In Progress Doctoral Candidates: Committee Chair and Advisor (3)

Dennis Fix, Applied Physiology, Exercise Science, Projected 2018, James Carson Chair Brandon Vanderveen, Applied Physiology, Exercise Science, Projected 2019, James Carson Chair Brittany Counts, Applied Physiology, Exercise Science, Projected 2020, James Carson Chair

Other Mentored Research 2004 American Physiological Society Frontiers in Physiology Professional Development Fellowship. A competitive summer fellowship program to provide a learning / research opportunity for public school science teachers offered by the American Physiological Society. Participant: Betsy Scarborough. Richland County School District 1 Middle School Science teacher. Mentor: James A. Carson., Project: “Liver Catalase activity during Cancer Cachexia”.

Scholarship: Post-Doctoral Fellow Supervision Kandy Velazquez 2016 – 2017 (NIH Diversity Post-Doctoral Supplement) Maria Lima, PhD; 2009 – 2011 (co-supervised with Dr. John Baynes) Jonathon Brock, PhD; 2007- 2008 (co-supervised with Dr, John Baynes)

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Scholarship: Masters Student Supervision Chair Master’s Thesis Committee (5)

Dennis Fix, Fall 2013, Thesis title: The effect of radiation dose on skeletal muscle morphology. Joshua Mangum, Fall 2013, Thesis title. Metabolic plasticity of cachectic Skeletal Muscle Sonia Thomas, Spring 2011 Thesis title “Succination in Diabetes ” Mark Cairns, Summer 2008 (currently in Medical School, U. South Carolina) Thesis title “Endotoxin and cachexia ” Jamie McClellan, Spring 2008 (graduate PhD USC Medical) Thesis title “pyridoxamine and cachexia”

Master’s Thesis Committee Member

Alex Souganis Spring 2015 Ryan Falick, Spring 2014 Lauren Verviake, Spring 2013 Claire Groschwitz, Spring 2005,

Supervised Exercise Science Masters Student Projects (8) Joshua Jefferies, 2015, “Strength Norms for South Carolina High School Athletes” Nathan Rice, Spring 2014, “Strength Changes in High School Athletes” Johannes Aartun, Spring 2012, “Exercise and Cancer Survival” Karina Howell, Summer 2010 “Training for landing and cutting stability in the female athlete” Brandon Cain, Spring 2010 “IL-6 and Colorectal Cancer” Nicole Reese, Fall 2009, title “COPD and Exercise” Matt Jepson, Spring 2009, title “Adipose Tissue Hypoxia: Linking Obesity to Insulin Resistance April Wilson, Spring 2005, title “NSAIDS and recovery from muscle damage” Jeremiah Blankenship, Spring 2005, title “Mixed Methods of Maximal Force training” Adrian Pinasco, Spring 2002, title “The Physiologic basis for Soccer training”

Other graduate students funded/supervised as research GA’s and under James Carson’s supervision for at least 1 semester

Johannes Aartun, fall 2010 – present, Applied Physiology MS Student Sonia Thomas, Fall 2009 – 2011, Applied Physiology MS student Amanda Clifford, Fall 2009, Applied Physiology MS student Ashly Artese, Spring –summer 2009 – Summer 2009, Applied Physiology MS student Nicole Reese, Fall 2008 – Fall 2009 present, Applied Physiology MS student Matt Jepson, Fall 2007 – Spring 2009, Applied Physiology MS student April Wilson, Fall 2004 - Spring 2005, Exercise Science Graduate Student graduated Spring 2005. Claire Groschwitz, spring 2002 – spring 2003, Exercise Science undergraduate and Master’s student, accepted into Veterinary School fall 2004. Steven Chen, 2002 spring – 2002 summer, Exercise Science Masters program, Robin Brewer, 2001 fall – 2002 spring, Exercise Science Masters student, Jill Maxwell, fall 2001, Exercise Science Masters program, graduated in 2003. Won Jun Lee, fall 2000 – spring 2003, Exercise Science Doctoral student, transferred to Pharmacy. Tonya Zier, fall 2000 – spring 2001, Exercise Science Master’s Student, graduated in 2001. Paul Burkhart, summer 2000, Exercise Science Graduate Student, graduated summer 2000.

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Scholarship: Mentored Graduate Student Fellowships & Grants SPARC Graduate Research Grant, University of South Carolina. 2017-18, $5,000 Student: Brittany Counts (EXSC Graduate Student); Principal Investigator: James A. Carson.. Title: The Effect of Cancer-Induced Cachexia on Skeletal Muscle Anabolic Flux SPARC Graduate Research Grant, University of South Carolina. 2017-18, $5,000 Student: Brandon Vanderveen (EXSC Graduate Student); Principal Investigator: James A. Carson.. Title: Calcium’s Role in the Disruption of Muscle Function and Protein Degradation During Cancer Cachexia SPARC Graduate Research Grant, University of South Carolina. 2015-16, $5,000 Student: Justin Hardee (EXSC Graduate Student); Principal Investigator: James A. Carson.. Title: mTORC1 Regulation of Muscle Protein Synthesis in a Mouse Model of Cancer Cachexia American College of Sports Medicine Graduate Student Research Award. 2015 – 2016, $4,842 Expenses Student: Justin Hardee (EXSC Graduate Student); Principal Investigator: James A. Carson.. Title: Skeletal Muscle Response to Low- and High-Frequency Electrical Stimulation. American College of Sports Medicine Graduate Student Research Award. 2013 - 2014 Student: Melissa Puppa (EXSC Graduate Student); Principal Investigator: James A. Carson.. Title: The regulation of mitochondrial plasticity by gp130r in skeletal muscle after contraction. $4,700 Expenses South East Alliance for Graduate Education and the Professoriate (SEAGEP), 2010-2011 Academic Year Student: Kandy Velazquez (EXSC Doctoral Candidate, Mentor: James Carson $4,000 Stipend South Carolina Space Grant Fellowship. South Carolina Space Grant Consortium 2005 – 2006 $7,500 Stipend Student: Tyrone Washington (EXSC Graduate Student); Principal Investigator: James A. Carson. American College of Sports Medicine Graduate Student Research Award. 2004 – 2005, $5,000 Student: Kristen Mehl (EXSC Graduate Student); Principal Investigator: James A. Carson.. Gatorade Sports Science Institute Graduate Student Research Program., 2004 – 2005, $1500 research expenses Student: Kristen Mehl (EXSC Graduate Student); Principal Investigator: James A. Carson . American College of Sports Medicine NASA Graduate Research Grant. ($5,000), 2003-2004 Student: Joseph M. McClung (EXSC Graduate Student); Principal Investigator: James A. Carson. American Federation For Aging Glenn Student Award For Research In The Area Of The Biology Of Aging. Research ($5,000), 2002 - 2003. Student: Raymond Thompson (EXSC Graduate Student); Principal Investigator: James A. Carson. Title: “Effect of Inflammation on Aged Skeletal Muscle Regeneration”. American College of Sports Medicine NASA Space Physiology Research Grant. ($2,500), 2002 - 2003. Student: Joseph McClung (EXSC Graduate Student); Principal Investigator: James A. Carson.

Gatorade Sports Science Institute Graduate Student Research Program. ($500), 2002 - 2003. Student: Joseph McClung (EXSC Graduate Student); Principal Investigator: James A. Carson Title: “Leucine administration as a countermeasure for unloading induced atrophy in rat skeletal muscle. Gatorade Sports Science Institute Student Grant Program. ($500), 2002 - 2003. Student: Christopher Bopp (EXSC Graduate Student); Principal Investigator: James A. Carson. Title: “Creatine Supplementation Effects on Cardiac Gene Expression. South Carolina Space Grant Consortium South Carolina Space Grant Fellowship, ($5,100), 2001 - 2002 Student: Tyrone Washington (EXSC Graduate Student); Principal Investigator: James A. Carson. South Carolina Space Grant Consortium South Carolina Space Grant Fellowship, ($7,175), 2001 - 2002. Student: Joseph McClung (EXSC Graduate Student); Principal Investigator: James A. Carson.

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Scholarship: AWARDS: Mentored Graduate Student Research 2015 Southeastern Chapter American College of Sports Medicine. Jacksonville FL, Feb. 2015. 1st Place – Doctoral Student Research Award. Student: Justin Hardee (Carson doctoral student). Submission titled “Cachectic skeletal muscle response to contractions: a role for Stat3 signaling”.

2013 Southeastern Chapter American College of Sports Medicine. Greenville SC, Feb. 2013. 1st Place – Doctoral Student Research Award. Student: Melissa Puppa (Carson doctoral student). Submission titled “Cachectic skeletal muscle response to a novel bout of low frequency stimulation”. 2010 Graduate Student Day, University of South Carolina, April 2010. 1st Place, Graduate Student Research Award, Health & Life Sciences Category (Poster). Student: James White (Carson doctoral student). Submission titled “Skeletal muscle protein synthesis and cancer cachexia in the ApcMin/+ mouse

2007 Midwestern Chapter American College of Sports Medicine. October 2007 Outstanding Doctoral Student Oral Communications Presentation. Student: Tyrone Washington (Carson Doctoral Student) Submission: Interleukin-6 deficiency attenuates the recovery of gastrocnemius muscle mass from disuse-induced atrophy. 2006 Southe3astern Chapter American College of Sports Medicine. Charlotte, North Carolina, Feb. 2006. 2nd Place - Graduate Student Research Award. Student: Kristen Mehl (Carson doctoral student). Submission titled “The Role of IL-6 in Cancer Cachexia Induced Muscle Wasting in the ApcMin/+ mouse”. 2005 South Carolina Nutrition Research Consortium Research Summit ––. Columbia, SC November 2005. First Place - Graduate Student Poster Award; Student: Kristen Mehl (Carson doctoral student). Submission “The interaction of a high-fat diet and exercise on intestinal polyp development in ApcMin/+ mice”. 2004 Southeastern Chapter American College of Sports Medicine. –. Atlanta, Georgia, Jan. 2004. 3rd place Graduate Student Research Award. Student: Kristen Mehl (Carson doctoral student) Submission titled “Physical activity decreases intestinal polyp development in the APCmin+/- mouse”. 2003 University of South Carolina – Graduate Student Day Oral Presentation. Research Award; Health ($400). Principal Student Investigator: Joseph M. McClung (Carson Doctoral Student). Submission: “Pro-inflammatory cytokine expression in aged regenerating skeletal muscle.” 2002 University of South Carolina Graduate Student Day Columbia, SC, March 2002. Oral presentation Research Award ($400). Student: Joseph McClung (Carson Doctoral Student) Submission: “RhoA induction by functional overload and nandrolone decanoate in rat skeletal muscle”. 2002 Southeastern Chapter American College of Sports Medicine. Atlanta, Georgia. 1st Place - Outstanding Doctoral Student Research Award ($500). Student: Joseph McClung (Carson Doctoral Student) Submission titled “RhoA induction by functional overload in rat skeletal muscle”. 2002 Beta Kappa Chi Scientific Honor Society / National Institute of Science Brookhaven Graduate Student Oral Presentation Research Award ($500). Student: Tyrone Washington. Submission: “Decreased lactate dehydogenase activity at the onset of functional overload in rat plantaris muscle”. 2002 Beta Kappa Chi Scientific Honor Society / National Institute of Science Brookhaven . Graduate Student Oral Presentation Research Award ($300). Student: Joseph McClung. Submission titled “RhoA expression and skeletal muscle hypertrophy” 2002 National Institute of Science, Columbia, SC, 2002. Graduate Student Oral Presentation Research Award ($300). Student: Joseph McClung Submission titled “RhoA induction by functional overload and nandrolone decanoate in rat skeletal muscle”.

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Scholarship: Research Grants

PENDING

1 R21 as PI, several R01 grants as co-I ACTIVE 1R01AR065826 RO1 (Toth M PI,) 07/1/2016 – 6/30/2021 0.6 calendar NIH/ NIAMS $170,197 (sub contract)

Status: Funded Carson JA Co-I (sub contract, Vermont College of Medicine) Skeletal Muscle Atrophy and Dysfunction in Human Cancer Aim 2 will determine if mechanical signaling can mitigate human tumor-derived factors and cancer therapeutic regulation of both myotube size and mitochondrial function. A portion of specific aim 2 will be performed at the University of South Carolina in Dr. James Carson’s laboratory. Dr. Carson will perform analysis related to examining the effects of human tumor-derived factors and cancer therapies on myotube biology and their interaction with muscle mechanical stimuli 5P30GM103336 (Murphy PI) 9/1/2016 – 7/31/2018 NIH /NIGMS $113,300 total cost Center for Colon Cancer Research. Carson co-investigator, other investigators: A. Murphy, M Pena Title: Pilot Project: The role of the gut microbiome in tumor development and response to therapy RO1 CA121249- (Carson PI) 04/15/2014 – 2/28/2019 2.0 calendar National Institutes of Health / NCI $1,483,315 (5yr); $296,663 yr Status: Funded Other investigators: Angela Murphy, Mark Pena Title: Cachexia in ApcMIN/+ mice: The role of IL-6

5P30GM103336 (Berger PI) 7/1/2013 – 6/30/2018 1.0 calendar NIH /NIGMS Center For Colon Cancer Research. Associate Director (Carson) Phase III Center Grant

Selected Grant Funding Completed

National Institutes of Health Related Funding (over 3.4 million dollars) RO1 CA121249-01A2 (Carson PI) April 2008 – March 2013 2.4 calendar NIH / NCI $1,118,000 (Total costs) Title: Cachexia in ApcMIN/+ mice: The role of IL-6 R37 DK01997 1-31 (PI Baynes; Carson co-PI) Sept 2007 – July 2011 1.5 calendar NIH / NIDDK/ $1,492,100 (Total Costs)

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Title: Glycation of Protein in Diabetes

R21 CA135377-01A1 (PI Murphy) Sept 2009 – August 2011 0.36 calendar NIH / NCI $540,000 total cost Carson Co-I Title: Curcumin and Quercetin in Colon Cancer: Role of Macrophage-Induced Inflammation RO3 AR051434-01A1 (Carson PI) July 2005 – June 2007 2.4 calendar NIH / NIAMS $139, 130 total cost Title: Androgen’s role in skeletal muscle regeneration

F32 AR008328-01 (Carson PI, Booth Mentor) June 1994 – May 1997 12.0 calendar NRSA , Post-Doctoral Training Fellowship, $75,000 NIH / NIAMS

Title: Chicken -actin promoter function during hypertrophy

National Institutes of Health National Center Related Funding 5P30GM103336 (Seed Grant Chatterjee S. PI) 09/1/2015 – 8/30/2016 Center for Colon Cancer Research at USC $50,000 Status: Funded Carson JA Co-I Title: Pilot Project: TLR4-induced miRs as molecular signature in NALFD potentiation of colon neoplasia P20 (Nagarkatti) 03/2013 – 02/2014 NIH / NCRR $10,000 U South Carolina COBRE Center for Dietary Supplements & Inflammation Carson Pilot Project Grant PI Title: Quercetin supplementation and the prevention of gut barrier dysfunction during cancer cachexia

P20 RR-017698 (target PI Fayad) July 2010 – June 2012 1.0 calendar NIH / NCRR Center for Colon Cancer Research at USC Mentor: James A. Carson (1 month salary) Title: The role of Selenium and adiponectin in chronic inflammation-induced colon cancer

P20 RR-017698 (Carson ) 11/1/10 – 6/31/11 NIH / NCRR $50,000 (Direct) Center for Colon Cancer Research at USC Title: Gut barrier dysfunction in 2 distinct models of cancer cachexia in mice

Shared Instrumentation Grant (Price) 02/2010 NIH / NCRR $381,491 (Direct)

Investigator: James Carson (instrumentation grant); contributed to grant proposal Title: IVIS Spectrum Imaging System for the University of South Carolina P20 RR-017698 (Berger) 7/1/08 – 6/31/09 NIH / NCRR $50,000 (Direct) Center for Colon Cancer Research at USC James A. Carson Pilot Project PI Title: Pilot Project: Gut barrier Dysfunction: The trigger for cachexia in ApcMin/+ mice

P20 RR-017698 (Berger) 9/1/05 – 6/31/07 NIH / NCRR $140,000 (Direct)

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Center for Colon Cancer Research at USC James A. Carson COBRE Target PI Title: Target PI: The effect of physical activity on intestinal polyp formation in the Apcmin mouse

P20 RR-017698 (Berger) 1/03 – 7/04 NIH / NCRR $80,000 (Direct) Center for Colon Cancer Research at USC James A. Carson COBRE Target PI Title: The effect of physical activity on intestinal polyp formation in the Apcmin mouse Other Completed Funding Source: American Heart Association Mid-Atlantic Region, Beginning Grant in Aid Submission: November 1999 Status: Funded Grant #: 0060173U Dates: 7/2000 – 6/2002 P rincipal Investigator : James A. Carson Title: Smooth muscle gamma actin gene activation by RhoA: A potential role in smooth muscle mechanical signaling Source: American Federation For Aging Research (AFAR), AFAR Research Grant Program Submission: December 1999 Status: Funded Dates 8/1/2000 – 6/31/2002 Funds: $50,000 Principal Investigator: James A. CarsonTitle: Serum Response Factor’s role in aged skeletal muscle’s blunted remodeling response to chronic stretch Source: The Ohio State University Graduate School. Submission: 1992 Status: Funded Dates 1992 - 1993 Funds: $900 Principal Investigator: James A. Carson; Mentor: Stephen Alway Title: The effect of aging on fiber number and satellite cell activation in the anterior latissimus dorsi muscle of the Japanese Quail after stretch-overload Source: National Science Foundation/EPSCoR grant # EPS-0132573 and NIH/BRIN grant # 8-PORR13461. Collaborative Research Program. Submission: February 2002 Status: Funded, expired Dates: 5/02 –12/03 Funds: $75,000 ($45K to Dr. Carson ) Principal Investigator: James A. Carson & Larry Lowe (Benedict College) Title: Aged Muscle’s Decreased Regenerative Capacity: Inflammation’s Critical Role. Aspire I Program (Carson), 05/091/2013 – 9/31/2014 0.0 calendar University of South Carolina VP Research Office $15,000 (1 year) ROLE OF IL-6 SIGNALING ON SKELETAL MUSCLE WASTING IN LEWIS LUNG CARCINOMA MODEL OF CACHEXIA Funds to generate preliminary data for grant submission related to IL-6 induced cachexia. Seed Grant (Carson) 03/01/214 – 02/28/215 0.0 calendar National Institutes of Health Grant P20 RR-017698 from the National Center for Research Resources, University of South Carolina Colorectal Cancer COBRE Program $5,000 (1 yr) Title: Measurement of muscle fiber type specific protein synthesis rates

Source: Arnold School of Public Health Seed Grant (USC Competitive internal) Status: Funded -USC internal Dates: June 2007 – May 2008 Funds: $5,000 (Direct Costs) Principal investigator: James A. Carson) Title: Inflammation and Cachexia in ApcMIN/+ mice Source: Research Consortium on Children and Families /USC Status: Funded – USC internal Dates: May 2006 – April 2007 Funds: $19, 998 Principal Investigator: Megan C. Kurlychek, Asst Prof. USC Criminology & Criminal Justice Investigator: James A. Carson

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Title: Performance enhancing drugs: A feasibility study in assessing motives, correlates, and outcomes among a general population of young adults. Source: Palmetto Health / South Carolina Cancer Center Status: Funded (#SCCC RO6-04); State initiative Dates: May 2006 – April 2007 Funds: $24,500 Principal Investigator: Greg Hand, Assoc. Prof. EXSC; Investigator: James A. Carson Title: The effect of long-term physical activity on markers of metabolic dysfunction and inflammation in elderly prostate cancer survivors. Source: South Carolina Nutrition Research Consortium Submission: April 2004 Status: Funded Dates 8/1/04 – 7/31/05 Funds: $20,000 Principal investigator: James A. Carson, co-investigator Dr. Stephanie Muga Title : Nutrition & Exercise intervention on intestinal polyp formation. Source: National Science Foundation/EPSCoR grant # EPS-0132573 and NIH/BRIN grant # 8-PORR13461. Collaborative Research Program. Submission: October 2003, Competitive 6 month Renewal of Collaborative project Status: Funded, expired Dates: 12/1/03 – 6/30/04 Funds: $35,000 ($30,000 to Dr. Carson at USC) Principal Investigator: James A. Carson & Larry Lowe (Benedict College) Title: Aged Muscle’s Decreased Regenerative Capacity: Inflammation’s Critical Role. Source: University of South Carolina Research Support Program, Developmental Grant Submission: January 2002 Status: Funded Dates 9/1/2002 – 6/30/2003 Funds: $15,000 Principal Investigator: James A. Carson Title: Aged Muscle’s Decreased Capacity For Regeneration: The Androgen Receptor’s Role Source: University of South Carolina School of Medicine – School of Public Health Collaborative research Incentive Program Submission: 2002 Status: Funded Dates 9/1/2002 – 8/31/2003 Funds: $20,000 Principal Investigators: Marlene Wilson & Gregory Hand Collaborative team Member : James Carson Title: Anxiety, Physical Activity, and Opioid Peptides Source: . University of South Carolina College of Nursing Center For Health Promotion and Risk Reduction in Special Populations. Submission: 2002 Status: Funded Dates 9/1/2002 – 8/31/2003 Funds: $10,000 Principal Investigators: Gregory Hand & Kenneth Phillips, Investigative team: James A. Carson Title: Developmental Grant. “Effects of Acupuncture and Nursing Back Rub on Stress-induced oral disease in HIV+ Individuals. Source: South Carolina Space Grant Consortium, Travel Grant / South Carolina Space Grant Consortium Submission: February 2000 Status: Funded Dates 7/1/2000 – 2/28/2001 Funds: $8,000 / 6 months Principal Investigator: James A. Carson Title: Androgen Therapy As A Counter Measure Against Unweighting-Induced Skeletal Muscle Atrophy

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Grant Submissions Not Funded Submitted, not funded

R21 (A Chanda PI) 7/1/2017 – 6/30/2018 0.6 calendar NIH / NCI $390,875 (2 yr) Status: Pending Carson JA Co-I Impact of Dietary Selenium Supplementation on Microbiome and Metabolite Profiles in ApcMIN Mice.

R01 (Koh HJ PI) 12/1/2016 – 11/30/2021 1.1 calendar NIH / NCI $1,250,000 (5 yr) Status: Pending Carson JA Co-I Insulin Signaling and TRB3 in Skeletal Muscle and Brown Adipose Tissue RO1 (Murphy A PI; Carson Co-I) 12/1/2016 – 11/30/2021 0.6 calendar NIH / NCI $1,688,750 (5yr) Status: Pending Carson JA Co-I Title: Targeting Macrophages in Obesity-Enhanced Breast Cancer R21 (Carson PI) 07/1/2016 – 6/30/2018 1.2 calendar National Institutes of Health / NCI $402,875 (2 yr) Status: Pending Linking Cancer Cachexia to Gut Dysbiosis VA Merit (Ginsberg J, Dorn VA) 7/1/2016 – 6/30 2019 0.6 calendar Veterans Affairs – Dorn Research Institute $567,454 (3yr – sub contract) Carson JA Co-I (sub contract) Autonomic Blunting and Restoration in Veterans with Gulf War Syndrome: The Heart Rate Variability Index of Cognitive Performance, Fatigue, and Rest/Activity R21 (Koh H PI, USC Exercise Science) 07/1/2016 – 6/30/2018 1.2 calendar National Institutes of Health / NIAMS $391,715 (2 yr) Status: Pending Carson JA Co-I The Role of TRB3 in Denervation- and Cancer Cachexia-induced Insulin Resistance

RO1 (Murphy A PI; Carson Co-I) 04/1/2016 – 3/30/2021 0.6 calendar National Institutes of Health / NCI $1,688,750 (5yr) Title: Targeting MCP-1 in Obesity-Enhanced Breast Cancer NASA Space Biology (Carson, sub Co-I) 12/01/14- 12/31/17 $250,000 year 1 1.0 calendar Mechanisms for Whole-Limb Atrophy During Long Duration Spaceflight. This research proposal address the degradation of skeletal, joint, and muscle tissue in the hind limb from long term spaceflight and recovery upon reloading NIH / NCI R21 (Fayad; Carson co-I) $393,710 (Total costs 2yr);09/01/2014 – 08/30/2016 3.0 calendar Co-investigator: James A. Carson Exercise and Adiponectin: Role in chronic inflammation-induced colon cancer

Submitted 2013, not funded

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NIH/NIAMS 1R21AR065015-01R21 (Carson) June 2014 – May 2016 $342,250 year 12.0 calenda Title: The role of gp130 receptor signaling in load-induced growth In the proposed study we will evaluate the role of muscle gp130 receptor and STAT3 signaling during overload induced hypertrophy and disuse atrophy in otherwise healthy mice. . Scored 33 percentile, reformatting for submission R21 National Institutes of Health / NCI Status: Submitted June 2013, Scored resubmitting, Dates: April 2014 – March 2016 Funds:$393,710 (Total costs 2yr); Principal investigator: Raja Fayad, Asst Professor USC EXSC Co-investigator: James A. Carson (3 calendar months) Title: Exercise and Adiponectin: Role in chronic inflammation-induced colon cancer

American Diabetes Association. Status: resubmission Not funded Dates: January 2014 – December 2017 Funds:$345,000 (Total costs) Principal investigator: James A. Carson (1 calendar month) Other investigators: Raja Fayad, Angela Murphy Title: The Muscle gp130 Receptor’s Role in Muscle Protein and Metabolic Regulation During High Fat Diet-induced Obesity.

R21 National Institutes of Health / NIAMS. Status: Scored 42, not funded, will resubmit Dates: June 2013 – May 2015. Funds:$685,000 (Total costs 2yr); $342,250 first year. Principal investigator: James A. Carson (2 calendar months). Title: The role of gp130 receptor signaling in load-induced growth Source: R01 National Institutes of Health / National Cancer Institute. Status: Scored 30, in revision and will resubmit 2013. Dates: April 2013 – March 2018. Funds:$1,756, 250 (Total costs 5yr); $342,250 first year. Principal investigator: James A. Carson (2 calendar months). Other investigators: Angela Murphy, J. Mark Davis Title: Cachexia in ApcMIN/+ mice: The role of IL-6 Source: American Diabetes Association Status: Not Funded g, Basic Science Grant Dates: January 2013 – December 2016 Funds:$345,000 (Total costs) Principal investigator: James A. Carson (1 calendar month) Other investigators: Raja Fayad Title: The Muscle gp130 Receptor’s Role in Muscle Protein and Metabolic Regulation During High Fat Diet-induced Obesity. National Space Biomedical Research Institute , Status: Not funded, submitted December 2011; Funds:$544,000 (total cost) subcontract to USC J Carson; Principal Investigator: Ted Bateman, Associate Professor, UNC- Chapel Hill, Co-investigator: James A. Carson (1 month salary); Title: Integrated Whole Joint Health: Time Course of Musculoskeletal and Cartilage Degradation / Recovery for Microgravity and Space Radiation National Institutes of Health / National Cancer Institute, Status: Scored, not funded, resubmit, Dates: 4/1/12 – 3/31/14; Principal Investigator: Elizabeth Murphy, Assistant Professor , USC School of Medicine, Co-investigator: James A. Carson (0.27 months); Funds: $376,760 (Total) Title: Macrophages in High Fat Diet Enhanced Colorectal Cancer: Regulation by miRNA-155 National Institutes of Health / NIAMS, 4/1/12 – 3/31/14, Principal Investigator: Matthew Kostek, Assistant Professor EXSC, USC, Co-investigator: James A. Carson (0.9 months), Funds: $379,850 (Total) Title: PGC1-alpha, Utrophin, and Muscle Function Response to Resveratrol in mdx Mice National Institutes of Health / National Center for Research Resources, Dates: 4/1/12 – 3/31/13, Principal Investigator: Robert Price, USC School of Medicine, Co-investigator: James A. Carson Funds: $702,999 (Total) Core instrumentation instrument, Title: GATAN 3View Serial Block Face Scanning Electron Microscope on a Zeiss Sigma SEM National Institutes of Health / National Cancer Institute , Status: R01 not funded resubmit , Submitted: June 2010, Funds: $1,500,000 total cost; Principal Investigator: Angela Murphy (Assistant Professor, USC School of Medicine), Co-Principal Investigator: James Carson (5% effort) Title: Multi-targeted prevention of obesity-enhanced cancer by quercetin: Role of SIRT1 National Institutes of Health , Status: R21 not funded submission TBD, Submitted: June 2010, Funds: $404,250 total cost; Principal Investigator: Jeff Patton (Associate Professor, USC School of Medicine), Co-Investigator: James Carson (sub contract) Title: Pathogenesis of Mitochondrial Myopathy and Sideroblastic Anemia (MLASA)

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Cancer Prevention & Research Institute of Texas, Status: Submitted :June 2010; Principal Investigator: Yi-Ping Li (Associate Professor, University of Texas Medical School Houston), Co-investigator: James Carson (sub contract) Title: The Role of Autophagy in Cancer Cachexia National Institutes of Health / National Institute of Diabetes & Digestive Diseases (NIDDK/NIH) , Submission: RO1 submitted February 2010, Status: Not funded, plan to revise and resubmit , Funds:$1,138,400 (Total costs), Principal investigator: Norma Frizzell , Co-PI: James A. Carson (0.9 calendar months) Title: The Role of Succination in Endoplasmic Reticulum Stress in the Diabetic Adipocyte Submitted 2009, & earlier , over 45 grant submissions not funded

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Scholarship: Speaking Presentations

Research talks Upcoming invited talks

Integrative Physiology of Exercise Meeting, SanDiego CA, Sept. 2018. Symposium speaker (2 talks)

American College of Sports Medicine National Meeting, Minnepolis MN, June 2018. SUmposium speaker

2017 10th International Conference on Cachexia, Sarcopenia, and Muscle Wasting, Rome Italy, December 2017, invited speaker s “Sex differences in cachexia, sarcopenia, and wasting disorders”. (Opening session)

10th International Conference on Cachexia, Sarcopenia, and Muscle Wasting, Rome Italy, December 2017, invited speaker “The muscle gp130 receptor’s role for cancer induced anabolic resistance”. Basic Track: Tumorsecreted factors, cytokines and cachexia development symposium.

Biology Seminar Series Speaker, University of North Carolina Charlotte, Invited Speaker. March 2017 Center for Colon Cancer Research, University of South Carolina; Research Retreat, Invited Speaker. “Gut Microbiome, Chemotherapy and Intestinal Tumor Development” January 2017

2016

9th International Conference on Cachexia, Sarcopenia, and Muscle Wasting, Berlin Germany, December 2016, Invited speaker symposium “Exercise, nutrition, and metabolic problems in cachexia”. College of Pharmacy, University of South Carolina. November 2016. Invited Seminar speaker.

3rd Cancer Cachexia Conference, September 2016, Washington DC, invited symposium speaker.

University of Indiana University School of Medicine, February 25, 2016, Indianapolis IN, Invited lecture, canceled due to flight issues with weather. 2016 Advances in Skeletal Muscle Biology in Health and Disease, January 2016, Gainesville FL, Invited symposium speaker. 2015 8th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Paris France, December 2015, Invited speaker symposium muscle mitochondria and cachexia. American College of Sports Medicine National Meeting. San Diego . Invited Speaker in a symposium “Fatigue with disease and Inflammation ” and talk title “Combatting cancer fatigue: The interaction of inflammation and exercise. ” May 2015. Experimental Biology Meeting, American Physiological Society, Session Chair, Boston MA. EEP Symposium title “ Molecular Mechanisms of Muscle Atrophy, Hypertrophy and MicroRNA”. April 2015. 2014 University Of Arkansas Medical School Grand Rounds Endocrinology, Invited Little Rock AR, December 2014.Title “Regulation of Cancer Cachexia-induced Muscle Wasting by the gp130 receptor: A role for exercise”. University Of Nebraska Medical School Cancer Biology Seminar Series, Invited Omaha NE, November 2014.Title “The role of the gp130 receptor in cancer cachexia progression”. International Cachexia Conference, Montreal Canada, Invited Symposia Participant, September 20 2014. “Mitochondria Dysfunction and Cancer Cachexia. University of Kentucky Medical School, Muscle Biology Seminar Series, Lexington Kentucky. Invited speaker. “Muscle wasting with cancer: A role for the gp130 receptor and exercise. July 2014 Experimental Biology Meeting, American Physiological Society, Invited speaker, San Diego CA. EEP symposium Molecular Mechanisms of Muscle Atrophy, title “Il-6 & Muscle Remodeling with Cancer Cachexia. April 2014.

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COBRE Center for Dietary Supplements & Inflammation Seminar Series, USC School of Medicine, Columbia SC. Invited Speaker. “Quercetin supplementation and the prevention of gut barrier dysfunction during cancer cachexia”. March 2014 2013 Texas Tech University, Exercise and Sports Science Department, Lubbock TX, Invited Speaker. “The regulation of protein turnover with cancer cachexia,: A role for exercise”, November 2013. Presbyterian College Biology Seminar Series, Clinton SC, Invited Speaker. “Improving Cancer Patient Survival: Understanding Cachexia’s role” September 2013. York University Kinesiology program, Toronto Canada, Invited Speaker. “The regulation of protein turnover with cancer cachexia,: A role for the gp130 receptor”, August 2013. Galaxo Smith Kline Muscle Research Group, Raleigh NC, Invited Speaker. “The regulation of protein turnover with cancer cachexia: A role for the gp130 receptor”, March 2013. The Ohio State University James Cancer Center, Cachexia Research Group Seminar Series, Columbus Ohio, Invited Speaker. “The regulation of protein turnover with cancer cachexia,: A role for the gp130 receptor”, March 2013. 2012 Marshall University, Huntington WVA, Cell Differentiation and Development Center Seminar Series Invited Speaker. “IL-6 and cancer cachexia: A role for exercise” March 2012. Advances in Skeletal Muscle Biology in Health & Disease, University of Florida, Gainesville, Invited Speaker in Symposium “Muscle Protein Turnover With Cachexia: A role for exercise and contraction. February 2012 Southeastern Chapter of American College of Sports Medicine Meeting. Jacksonville FL Invited Speaker in a symposium “Gut Barrier function in ApcMin mice” February 2012 Kansas University, Health Sport and Exercise Science Department Seminar Program, Lawrence , KS Invited Speaker. “IL-6 and cancer cachexia” January 2012 2011 & Earlier Louisiana State University, Exercise Science Department, Seminar Program, Baton Rouge, La Invited Speaker. “IL-6 and cancer cachexia” November 2011 Case Western Reserve Medical School, Cancer Center Seminar Program Invited Speaker. “IL-6 and cancer cachexia” November 2011 Center for Colon Cancer Research, University of South Carolina; Research Retreat, Invited Speaker. “Gut Barrier function in ApcMin mice” January 2011 Center for Colon Cancer Research, University of South Carolina Seminar, “IL-6 and Cancer Cachexia” Oct. 2010 Syracuse University, Exercise Science Department Seminar. Invited Speaker. Muscle wasting and cancer cachexia: The role of Il-6. February 2010. 5th International Cachexia Conference, Barcelona Spain. December 2009. Invited speaker: Muscle regeneration with cachexia. Penn State University, Noll Physiology Lab & Kinesiology Department Seminar Series. Invited Speaker. Muscle wasting and cancer cachexia: The role of Il-6. October 2009. University of South Carolina School of Medicine: Biomedical Sciences Seminar Series, Invited Speaker. “Muscle wasting with cancer cachexia” March 2009. Center for Colon Cancer Research, University of South Carolina; Research Retreat, Invited Speaker. “Gut Barrier Dysfunction and Cancer Cachexia” January 2009 West Virginia Medical School: Exercise Science Seminar Series, Invited Speaker Exercise Science Department, West Virginia School of Medicine Speaker. “IL-6 & Wasting” November 2008.

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American College of Sports Medicine National Meeting. Indianapolis IN. Invited Speaker in a symposium “Wasting Diseases in Humans: From Animal research to Clinical Application ” and talk title “Hormone & Cytokine Influence on Muscle Wasting” May 2008. Molecular Genetics Seminar Series, Animal Science Department, Iowa State University. Invited Seminar Speaker. “IL-6 & Wasting” April 2007. American College of Sports Medicine National Meeting. Denver CO. Invited Speaker in a symposium “Hormones and muscle regeneration”. June, 2006. American College of Sports Medicine National Meeting. Denver CO. Research Presentation “The role of IL-6 in Overload-induced Muscle Growth”. June, 2006 American College of Sports Medicine National Meeting. Nashville TN. Invited Speaker in a symposium “Muscle wasting mechanisms”. June, 2005. University of South Carolina COBRE Colorectal Cancer Group. University of South Carolina (Dr. Frank Berger Chair), titled “Mechanisms inducing of muscle wasting with cancer cachexia. Columbia, South Carolina. May 2005. Invited Speaker Southeast Regional Chapter American College of Sports Medicine. Charlotte NC. Invited Speaker in a symposium. Talk title “Mechanisms of Muscle Wasting”. January, 2005 University of South Carolina COBRE Colorectal Cancer Group. University of South Carolina (Dr. Frank Berger Chair), titled “Exercise and Intestinal Polyp Formation in the APCmin Mouse. Columbia, South Carolina. April 2004. Invited Speaker. South Carolina Cancer Center. University of South Carolina. October 2003. Invited speaker. Title: Exercise & APCmin mouse polyp formation. American College of Sports Medicine National Meeting. San Francisco CA. Invited Speaker “Immunology and Skeletal Muscle Adaptation Symposium”. June, 2003. Medical College of Georgia Physiology Seminar Series, Medical College of Georgia Physiology Department, November 2002, Invited Speaker. University of South Carolina COBRE Colorectal Cancer Group. University of South Carolina (Dr. Frank Berger Chair), November 2002. Invited Speaker. University of South Carolina, Biological Sciences Seminar Series. University of South Carolina, October 2002. Invited Speaker. University of South Carolina, Department of Exercise Science Seminar Series. University of South Carolina, August 2002. Invited Speaker. American College of Sports Medicine National Meeting. St. Louis, Missouri. Invited Speaker “Dose response of Exercise Symposium”. June, 2002. University of Florida Department of Exercise Science Seminar Series. University of Florida, Department of Exercise Science, March 2001. Invited Speaker. University of Georgia Department of Exercise Science Seminar Series. University of Georgia, Department of Exercise Science, March 2001. Invited Speaker University of Missouri Veterinary Sciences Seminar Series. University of Missouri Veterinary School, Columbia Missouri, February 2001. Invited Speaker Southeast Regional Chapter American College of Sports Medicine. Regional Meeting, Columbia SC. Organizer & speaker of a symposium entitled “The effect of altered loading on skeletal muscle gene expression and function”. January 27, 2001 Basic Sciences Biomedical Seminar Series, University of South Carolina School of Medicine, Columbia SC. November 20, 2000. Invited Speaker

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Developmental Biology Weekly Departmental Meeting, University of South Carolina Medical School, Columbia SC, October 1999. Invited Speaker American College of Sports Medicine National Meeting. Seattle, WA. Invited Speaker “Molecular Regulation of Aging Symposium”. June, 1999, Invited Speaker. American College of Sports Medicine National Meeting, Denver, CO. Invited Speaker “The Regulation of Striated Muscle Hypertrophy Symposium”. May, 1997 1996 American Physiological Society Intersociety Meeting; Integrative Biology of Exercise. Vancouver, British Columbia. Invited Speaker “Plasticity of Muscle Symposium”. October, 1996. Department of Integrative Biology, Physiology, and Pharmacology Intramural Seminar Series. The University of Texas Health Science Center, Houston., September, 1996. Department of Integrative Biology, Summer Lecture Series. The University of Texas Health Science Center, Houston., July, 1996. Department of Integrative Biology, Summer Lecture Series. The University of Texas Health Science Center, Houston., July, 1995. American College of Sports Medicine National Meeting, Minneapolis, Minn. Session “Muscle and Regulatory Mechanisms”. June, 1995. Department of Physiology and Cell Biology, Summer Lecture Series. The University of Texas Health Science Center, Houston., June, 1994. American College of Sports Medicine National Meeting, Indianapolis Ind. Molecular Mechanisms Interest Group. June, 1994. Department of Cardiology, Guest Presentation. The University of Texas Health Science Center, Houston, 1994 Department of Physiology and Cell Biology, Brown Bag Presentation Series. The University of Texas Health Science Center, Houston, October, 1993. Department of Exercise Science, Seminar Series. Ohio State University,1993. Department of Veterinary Anatomy and Cell Biology, Guest Presenter. The Ohio State University, 1992 Department of Exercise Science, Seminar Series. Ohio State University,1992. Department of Exercise Science, Seminar Series. Ohio State University, 1990.

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Speaking Presentations (Continued) Instructional / Professional / Service

Completed Biology Seminar, Allen University. Invited “Graduate School Opportunities in Public Health and Exercise Science at the University of South Carolina”. March 27, 2017 Center for Colon Cancer Research at USC Monthly Meeting, Invited, “Understanding Updates on NIH Grant Proposals Involving the Premise, Rigor, Transparency” March 23, 2017 American Kinesiology Association Annual Meeting, Dallas Texas. Invited speaker. January 2017 “USING UNIVERSITY WIDE RESEARCH CENTERS AND COBRE PROGRAMS TO DEVELOP RESEARCH OPPORTUNITIES” and “THE VALUE OF INTERDISCIPLINARY DOCTORAL PROGRAMS AT THE UNIVERSITY OF SOUTH CAROLINA Exercise Science Seminar Series, University of South Carolina. “Professional Development: NIH Fellowship Evaluation and Content”. October 27, 2016 Fulmer Middle School Career Day, West Columbia SC. “What is Public Health?”. May 2016 Mouse Club Monthly Seminar, Biomedical Sciences Department University of South Carolina. “Setting the Stage: Mouse Metabolic and Functional Testing in Biomedical Research”. May 3, 2016 South Carolina High School Science Teacher Visit to USC, University of South Carolina. “Colon Cancer Research at the University of South Carolina”. April 9, 2016 Center for Colon Cancer Research at USC. “The Lasting Legacy of Raja Fayad’s Colon Cancer Research: Opportunities for future therapeutic breakthroughs”. March 2016 Wofford College, Spartanburg SC, Invited Speaker. “Physical Activity and Health: Exercise Science at USC.” January 2015 Johnson C Smith University, Biochemistry/Chemistry Seminar Series, Charlotte NC, Invited Speaker. “Colon Cancer Research at the University of South Carolina” March 2014 Exercise Science Department Seminar, University of South Carolina. “Perspectives on Departmental leadership: Dealing effectively with opportunities and challenges”. September 2014 University of South Carolina NIH/IDEA meeting, Columbia SC, Invited. “The Center for Colon Cancer Research at the University of South Carolina: Progress and Updates ” November 2014 Colon Cancer Research Gala Luncheon, Columbia SC, Invited. “The scope of colon cancer research at the University of South Carolina ” March 2014 South Carolina High School Strength Coaches Annual Meeting, Columbia SC, Invited Speaker. “Analysis of 2003 -2013 Strength Championship Data: insights and conclusions” January 2014 Presbyterian College Biology Seminar Program, Clinton SC. “Improving Cancer Patient Survival: Understanding cachexia’s role”. September 12, 2013 Presidential Fellows Professional Development Seminar, University of South Carolina. “Meet James Carson”. October 5, 2012. South Carolina High School Coaches Annual Meeting, Greenville SC, Invited Seminar Speaker. “Conditioning Pitfalls related to the High School Athlete” July 2010

Richland School District 1 Coaches Convocation 2009, Columbia SC, Invited Seminar Speaker. “Using Data to evaluate middle school and high school athletes: The role of exercise testing”. August 14, 2009.

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South Carolina High School Coaches Annual Meeting, Charleston SC, Invited Seminar Speaker. “Exercise Physiology & Training” July 2009. South Carolina High School Coaches Annual Meeting, Charleston SC, Invited Seminar Speaker. “Exercise Physiology & Training” July 2008. South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic, University of South Carolina, Invited Seminar Speaker. “Adaptations to Resistance Exercise” April 2008. South Carolina High School Coaches Annual Meeting, Charleston SC, Invited Seminar Speaker. “Core training” July 2007. South Carolina Athletic Trainers Association Annual Meeting, Columbia SC, Invited Seminar Speaker. “Inflammation: Friend or Foe” July 2007. South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic. University of South Carolina. Invited Speaker. Title “Muscle Hypertrophy: What have we learned?” May 2007 South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic. Charleston Southern University, March 2006. Invited Speaker. Title “Functional Testing: What can it tell us?”.

South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic. Charleston Southern University, May 2005. Invited Speaker. Title “Muscle Hypertrophy with Resistance Training”.

Trident Annual Sports Medicine Conference. Charleston, South Carolina, June 2004. Invited Speaker. Title “Female Resistance Training; What modulates the response?

South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic. Charleston Southern University, June 2004. Invited Speaker. Title “Ergogenic Aids and muscle mass changes with resistance Exercise.

South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic. University of South Carolina, June 2003. Invited Speaker. Title “ Female adaptations to resistance training.

South Carolina Chapter of the National Strength & Conditioning Association Annual Clinic. University of South Carolina, Columbia, June 2002. Invited Speaker. Title “ Youth adaptation to resistance training”.

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Teaching Teaching Awards

• Nominated for the Arnold School of Public Health Keith Teaching Award, 2004, 2009, 2012, 2013.

• Nominated for the University of South Carolina Key Award for Integrating Undergraduate Teaching and Research, Spring 2007.

Last Peer Review of teaching evaluation Spring 2014, Rating of 5 (out of 5), excellent rating Recent Student evaluations for courses entirely taught by J Carson Course N University wide (5 high) Effectiveness (5 high)

EXSC 755 Resistance Training & Disease Sum 2017 3/6 4.9 5.0 EXSC 781 Exercise Physiology II (3h) Spring 2017 5/6 5.0 5.0 EXSC 695 Writing in Research (3h) Summer 2016 7/7 4.9 4.6 EXSC 781 Exercise Physiology II (3h) Spring 2016 9/9 4.6 4.7 EXSC 880 Myology (3h) Sum 2015 5/7 4.4–4.8 4.6 EXSC 781 Exercise Physiology II (3h) Spring 2015 9/13 4.4–4.7 4.6 EXSC 695 Writing in Research (3h) Fall 2014 10/15 4.6-4.8 4.5 EXSC 755: Muscle Overload Sum 2014 5/10 4.6 – 5.0 4.7 EXSC 223 A & P 1 (3h) Sum 2014 21 4.4-4.7 4.7 EXSC 781 Exercise Physiology II (3h) Spring 2014 7/10 4.8 4.9 EXSC 695 Writing in Research (3h) Spring 2014 10/11 4.5 4.7 EXSC 880 Myology (3h) Sum 2013 12 4.7 4.7 EXSC 223 A&P 1 (3h) Sum 2013 33 4.5 4.1 Recent Courses Taught Summer 2016 EXSC 755 Overload & Resistance Training in Aging & Disease (ORTAD), 3h (N=6), EXSC 899 Dissertation Preparation, 4 total credit hours, (N=2) Spring 2017 EXSC 781 Advanced Exercise Physiology II, 3h (N=6), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=11), coordinate seminar series for department EXSC 899 Dissertation Preparation, 9 total credit hours, 1-5 h, N=5 BIOL 399 Independent study (N=1) Molecular Biology Lab in Cancer Fall 2016 (1 course release, chair duties) CHEM 496 Independent Study in Laboratory 3h (N=1) EXSC 777 Exercise and Endocrine Function (Davis) 3h, taught 1 lecture on anabolic hormones EXSC 783 Exercise Science Seminar series 1h (N=14), coordinate seminar series for department EXSC 899 Dissertation Preparation, 6 total credit hours, 1-3h (N=3), 7h total Summer 2016 EXSC 695 Writing and Presenting in Research, 3h (N=7), graduate (6) EXSC 899 Dissertation Preparation, 1 total credit hours, (N=1) Spring 2016 EXSC 781 Advanced Exercise Physiology II, 3h (N=9), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=11), coordinate seminar series for department EXSC 899 Dissertation Preparation, 9 total credit hours, 1-5 h, N=5 BIOL 399 Independent study (N=1) Molecular Biology Lab in Cancer Fall 2015 (1 course release, chair duties) EXSC 777 Exercise and Endocrine Function (Davis) 3h, taught 1 lecture on anabolic hormones EXSC 783 Exercise Science Seminar series 1h (N=13), coordinate seminar series for department EXSC 899 Dissertation Preparation, 6 total credit hours, 1-3h (N=5), 7h total HNRS 499 Senior Thesis / Project (N=1, 3h) Summer 2015 EXSC 790 Graduate independent study, 3h (N=1), graduate research experience (3 credit h total) EXSC 880 Myology, 3h (N=7), coordinate and taught entire course

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EXSC 899 Dissertation Preparation, 6 total credit hours, 1-2h (N=5) Spring 2015 EXSC 781 Advanced Exercise Physiology II, 3h (N=13), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=13), coordinate seminar series for department EXSC 899 Dissertation Preparation 11 total credit hours, 1-4 h, N=4 Fall 2014 EXSC 695 Writing and Presenting in Research, 3h (N=15), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=21), coordinate seminar series for department EXSC 899 Dissertation Preparation 2 total credit hours, 1h (N=2) Summer 2014 EXSC 223 Anatomy & Physiology I, 4h (N=21), coordinate labs and taught all lectures EXSC 755 Skeletal muscle with aging and disease, 3h (N=12), coordinate and taught entire course EXSC 785 Advanced Exercise Physiology Lab, 3h (N=2), coordinate and taught entire course EXSC 790 Graduate independent study, 3h (N=1), graduate research experience (3 credit h total) EXSC 899 Dissertation Preparation 5 total credit hours, 1-2h (N=4) Spring 2014 BMEN 499 College Engr, Biomedical Engr Undergraduate Research (N=1) EXSC 695 Writing and Presenting in Research, 3h (N=12), coordinate and teach entire course EXSC 781 Advanced Exercise Physiology II, 3h (N=10), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=13), coordinate seminar series for department EXSC 799 Thesis Preparation, 6h (N=1), MS thesis EXSC 899 Dissertation Preparation 11 total credit hours, 1-4 h, N=4 Fall 2013 SCHA 499 Senior Thesis, 3h (N=3), undergraduate senior thesis (6h total) EXSC 499 Undergraduate Independent study, 3h, (N=1) laboratory research experience EXSC 695 Writing and Presenting in Research, 3h (N=4), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=20), coordinate seminar series for department EXSC 780 Graduate Exercise Physiology (Durstine) 3h, taught 25% of course EXSC 777 Exercise and Endocrine Function (Davis) 3h, taught 1 1.5h lecture on anabolic hormones EXSC 790 Mechanisms of Physical activity Health Relationship (Pate) 1h, taught 1 1h cancer lecture EXSC 798 Graduate Project, 3h (N=1), MS project EXSC 799 Thesis Preparation, 6h (N=1), MS thesis EXSC 899 Dissertation Preparation 11 total credit hours, 1-4 h, N=4 Summer 2013 BIOL 399 Undergraduate Independent Study, 3h (N=1) EXSC 223 Anatomy & Physiology I, 4h (N=39), coordinate labs and taught all lectures EXSC 785 Advanced Exercise Physiology Lab, 3h (N=2), coordinate and taught entire course EXSC 790 Graduate independent study, 3h (N=1), graduate research experience (3 credit h total) EXSC 799 Thesis Preparation, 3h (N=1), MS thesis EXSC 880 Myology, 3h (N=12), coordinate and taught entire course EXSC 899 Dissertation Preparation 5 total credit hours, 1-2h (N=4) Spring 2013 SCHC 390Z Honors College project, 1h (N=1) EXSC 499 Undergraduate Independent study, 3h, (N=1) laboratory research experience EXSC 695 Writing and Presenting in Research 3h (N=4), coordinate and teach entire course EXSC 781 Advanced Exercise Physiology II, 3h (N=12), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=14), coordinate seminar series for department EXSC 790 Graduate independent study, 1-2h (N=3), graduate research experience (4 credit h total) EXSC 799 Thesis Preparation, 4h (N=1), MS thesis EXSC 899 Dissertation Preparation 8 total credit hours, 1-3h, N=4 Fall 2012 EXSC 780 Graduate Exercise Physiology, 3h (N=29), taught entire course EXSC 777 Exercise and Endocrine Function (Davis) 3h, taught 1 lecture on anabolic hormones EXSC 783 Exercise Science Seminar series 1h (N=17), coordinate seminar series for department EXSC 899 Dissertation Preparation 6 total credit hours, 1-3h (N=3) Summer 2012 EXSC 223 Anatomy & Physiology I, 4h course, taught entire course (N=27 students) EXSC 785 Advanced Exercise Science Lab, 3h course, taught entire course (N=6 students)

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EXSC 790 Graduate Independent Study, 3h, supervised (N=1 students) EXSC 899 Dissertation Preparation 2h-4h, supervised (N=5 students) Spring 2012 EXSC 499 Undergraduate Independent study, 3h, (N=1) laboratory research experience EXSC 695 Writing and Presenting in Research 3h (N=2), coordinate and teach entire course EXSC 783 Exercise Science Seminar series 1h (N=21), coordinate seminar series for department EXSC 798 Graduate Project, 3h (N=1), MS project EXSC 899 Dissertation Preparation13 total credit hours, 1-6h (N=5) Fall 2011 EXSC 780 Graduate Exercise Physiology, 3h (N=40), taught entire course EXSC 777 Exercise and Endocrine Function (Davis) 3h, taught 1 lecture on anabolic hormones EXSC 783 Exercise Science Seminar series 1h (N=22), coordinate lseminar series for department EXSC 799 Thesis Preparation, 3h (N=1), MS thesis EXSC 899 Dissertation Preparation 19 total credit hours, 1-6h (N=5)

Courses developed or significantly modified as far as content and requirements by James Carson. EXSC 781 Advanced Exercise Physiology 2, University of South Carolina, Columbia. 2013 – Present. Designed course to cover advanced Exercise Physiology topics. EXSC 695 “Reading and Writing in Research”, University of South Carolina, Columbia. Spring 2003 - Present. I serve as the main instructor for an undergraduate and graduate exercise science majors. The course is a senior level research and design course. Topics include basic research design, data analysis, proposal writing, practical research experience and research presentation.

SCCC 376C “Skeletal Muscle Activity & Disease Prevention”, University of South Carolina, Columbia. I was asked by the South Carolina Honors College to develop and teach an Honors College course that would both educate and stimulate curiosity into biological research, The main objectives related to this course are to teach the scientific research process while learning the relationship of skeletal muscle activity with various physiological conditions related to disease.

EXSC 783 “Research Seminar in Exercise Science”, at the University of South Carolina, Columbia. Course designed to teach the components, and formation process of a scientific proposal. Components covered included introduction, specific aims, literature review, and methodology. Taught 100% of the course. EXSC 780 “Advanced Exercise Physiology I”, at the University of South Carolina, Columbia. Fall 1999- 2005 & 2007 - present The first in a series of required graduate level courses for exercise science masters, DPT and Ph.D. students. Topics were exercise physiology related to cardio-respiratory and skeletal muscle fitness. EXSC 785 “Advanced Exercise Physiology Lab”, at the University of South Carolina, Columbia. Summer 2000- present. A required course for thesis/research track graduate students. The course combines theory based lecture with practical lab experience. EXSC 755C “Special Topics in Exercise Science”, at the University of South Carolina, Columbia. Sum 2000 – 2005, 2014 This series of courses was designed by myself to expand the student’s knowledge of the physiological adaptations to skeletal muscle by reading and synthesizing current and classic research in specific topic areas. Topics: 2000: Skeletal Muscle Adaptation to Resistance Exercise in Youth, Adult and Aged Populations. 2001: Muscle Mass Maintenance / Hypertrophy During Wasting and Disuse. 2002 Aging and Skeletal Muscle. 2003 Skeletal muscle and hormones. 2004 Morphological and functional adaptations to resistance training. 2005 Cellular mechanisms of muscle growth 2014 Skeletal muscle adaptation to resistance training and overload with aging and disease (ORTAD)

EXSC 880 “Myology” at the University of South Carolina Columbia. A doctoral level course for Applied Physiology tract students. This course provides an in depth examination of skeletal muscle adaptation to exercise and training. Physiology for the Health Sciences at the University of South Carolina School of Medicine, Columbia. Spring 2000- 2002. I taught the muscle physiology portion of this course designed for all health science graduate students at the University of South Carolina. The course is offered through the Physiology and Pharmacology Department at the University of South Carolina School of Medicine.

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Service: University University Faculty Athletics Representative (FAR) Search Committee, Appointed by Provost Office, Fall 2013. University Committee on Tenure and Promotion (UCTP). ELECTED, 3 year term. Serve on faculty review panels, and review and present faculty files to the full committee. 2013 – 2014 (resigned to become Department Chair)

Faculty advisor for Exercise Science Club Student Organization. 2013 – present

University Athletics Advisory Committee. ELECTED, 3 year term. University-wide committee to advise the Faculty Senate on University Athletic matters. 2013 – 2016.

Integrated Biomedical Sciences Graduate Program Steering Committee. Appointed. University-wide committee to facilitate graduate student recruitment and retention in the Integrated Biomedical Graduate Program at the University of South Carolina. 2010 – 2016

Animal Care Users Group. Appointed. New University-wide committee to examine issues related to animal research on the South Carolina campus. 2010 – Present. Faculty advisor for South Carolina Club Football Student Organization. 2010 – 2014. (Club disbanded) Judge for the Junior Science & Humanities Symposium. 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017. Written evaluation of high school science papers for the competition. Head Judge Jr. Division General Science, Annual USC Central South Carolina Region II Science and Engineering Fair at the Carolina Coliseum, Columbia South Carolina. 2010 Institutional Animal Use and Care Committee, University of South Carolina, University President appointed full committee member. Monthly year round meeting where all animal use protocols to be performed at the University of South Carolina are reviewed and approved or rejected. 2001 - 2009. Head Judge Sr. Division General Science, Annual USC Central South Carolina Region II Science and Engineering Fair at the Carolina Coliseum, Columbia South Carolina. 2007 – 2009 Judge Graduate Student Day Competition, April, University of South Carolina 2007, 2008 2011 Appointed to University-wide Search Committee for Head Veterinarian at the University of South Carolina 2006 – 2007. Science Fair Judge, General Science Category, Annual USC Central South Carolina Region II Science and Engineering Fair at the Carolina Coliseum, Columbia South Carolina. 2003, 2004, 2005, 2006, 2007 University of South Carolina Faculty Senate. Appointed faculty senator representing the School of Public Health and the Department of Exercise Science. Monthly meetings to discuss and vote on issues pertaining to the governance of the University of South Carolina. 2002 – 2004. Institutional Animal Use and Care Committee, University of South Carolina, University President appointed alternate. Monthly year round meeting where all animal use protocols to be performed at the University of South Carolina are reviewed and approved or rejected. 2000-2001.

Service: Arnold School of Public Health

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Chair Search Committee for Department Epidemiology and Biostatistics Chair, 2016- 2017

Search Committee Member Cluster Hire in Physical Activity 2011 Director Physical Activity Research Task Force (future directions) 2010 – 2012 CEPH Certification Committee, Arnold School of Public Health 2009 – 2010 Research Advisory Committee. Arnold School of Public Health2007- Present ASPH Council of Graduate Directors, Arnold School of Public Health2007- Present Graduate Student Awards Committee, Arnold School of Public Health2007- Present Tenure & Promotion Committee, Arnold School of Public Health2005 – Present Research Faculty Review Committee, School of Public Health 2005- 2007 CEPH Committee for Criteria, School of Public Health 2000 – 2001 Grievance Committee, School of Public Health2000 – 2002 Human Subject Research Approval Committee School of Public Health. 2001 -2002

Service: Department of Exercise Science

Member Search Committee for EXSC Chair, 2013 –May 2014. Member Search Committee for 2 EXSC faculty positions, 2013 –2014 Chair Cluster Search Committee Exercise Science 2012 -2013 Director of the Weekly Exercise Science Department Seminar Series 2002 – present Director of Graduate Studies 2007 – present Undergraduate Advisory Committee 2010 – Present Search committee MC/R tenure track faculty search 2011 – 2012 Integrative Muscle Biology Journal Club, weekly 2001 – present Director Applied Physiology Division, 2004 – 2008 Co-Director of Scientific Foundations Undergraduate Track, 2001 – 2010 Chair Search Committee, Exercise Science tenure track Assistant Professor 2007 – 2008 Search Committee Member, Exercise Science tenure track Assistant Professor 2006-2007

Exercise Science Graduate Committee 2001 – 2005 Exercise Science Laboratory Equipment Safety Course 1999 – 2006 Integrative Muscle Biology laboratory Meeting, weekly 1999 - present Faculty Meetings, Science Department 1999 – present Undergraduate Committee, 1999 – 2001 Exercise Science Student Laboratory Risk Management Group , 1999 – 2000

Service: Professional

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Board Trustee Member, South East Chapter of American College of Sports Medicine, elected 2014 - 2016

Nominated and ran for ACSM Board of Trustees election (not elected). 2013 Elected Exercise Physiology Councilor, Environmental & Exercise Section, American Physiological Society. Term 2012 - 2015 Editorial Board, Exercise Sports Science Reviews (ESSR), American College of Sports Medicine.

2011 – 2014 American College of Sports Medicine Science Integration & Leadership Committee. 2009 – 2012 American College of Sports Medicine Research Advisory Committee. 2006 – 2009 South Carolina State Chapter of the National Strength and Conditioning Association (NSCA)

Secretary, and Clinic Director, 2001 - 2008 Helped establish South Carolina Chapter of the NSCA and currently hold Secretary

position on the executive board. Also set-up, organized, and administered the annual state clinic in June for 2002, 2003 & 2004. The 2002 & 2003 clinics were held in the Exercise Science Department at The University of South Carolina, Columbia. The 2004 clinic is being held at Charleston Southern University. The organization and annual clinic has steadily grown over the 3 years it has been in existence.

Manuscript review 2013 – 2017 Editorial Board, Journal of Applied Physiology 2009 – 2013 Editorial Board, American Journal of Physiology Integrative & Regulatory 2011 – 2014 Associate Editor, Exercise & Sports Science Reviews 1999 – 2003 Editorial Board, Journal of Applied Physiology. Manuscripts reviewed for:

Journal of Applied Physiology American Journal of Physiology (Cell Physiology, Endocrine & Metabolism) PLOS Journals Nature: Cell Biology Medicine Science Sports and Exercise Journal of Neuroscience Methods Life Sciences

International Journal of Sports Medicine

Service: Community

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2007 – 2010 South Carolina United Futbal Club, South Carolina’s largest community based, non-profit, youth soccer club. I served as an advisor to coaches and directors on conditioning and maturation issues. Include in-service activities. 2008 – 2010 Elected Board member, Irmo High School Yellow Jacket Club, fund raising arm for all Irmo High School athletics. 2003 -2005 Richland – Lexington Public School District 5 – appointed health professional on panel to examine sex education policies and curriculum delivery. 2003 -2005 2007 - 2012 Head Judge South Carolina High School Strength and Conditioning State Championships

2007 – Present Head Judge High School Region Strength and Conditioning Championships held at Byrnes High School and Woodruff High School

1999 – present. Provided coaches, players and parents with free advice, demonstrations and handouts regarding conditioning. Routinely (many years) work with and test male and female high school soccer athletes for coaches as requested for Phil Savitz (Irmo High, River Bluff High), Mike Mauldin (Dutch Fork High, Blythewood High) This service continues to be provided at no charge, last performed January 2014. 2004 Ben Lippen High School JV Football Defensive Coordinator 2005 Ben Lippen High School Varsity Football Defensive line coach

Certifications

• Certified Olympic Lifting Club Coach, USA Weightlifting, 2002

• Certified Strength and Conditioning Specialist (C.S.C.S.), National Strength and Conditioning Association (N.S.C.A.) (1992, expired).

• Class D licensed youth soccer coach through U.S. Soccer Association, 2000.

• National Youth Soccer Coaching Diploma, National Soccer Coaches Association of America 2001.