Current Impact of Neuroscience in Teaching and Learning

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    My chapter from new bookMind, Brain, Educationedited by David Sousa, Solution Tree

    Current Impact of Neuroscience in Teaching and Learning

    By Judy Willis, M.D., M.Ed

    Introduction

    The convergence of laboratory science and cognitive research has entered our

    classrooms. Welcome and invited by many educators who seek ways to breath life into

    increasingly compacted curriculum, evoking suspicion and anxiety in others who have

    experienced the negative impacts of mandated change without sufficient support. In this

    chapter I offer a perspective that may offer solace to the latter, and temper hastiness in

    the former.

    My background as an adult and child neurologist is the lens through which I

    evaluate the quality and potential applications of the new science of learning. It is,however, my own schooling when I returned to school in 1999 to earn my teaching

    credential and Masters of Education and my past ten years of classroom teaching that

    allow me the privilege of incorporating the theoretical wisdom of great educators who

    preceded the scanners and computers with the data these tools now offer. The pairing of

    what was believed before the laboratory research with current research interpretation

    suggests neuro-logicalteaching strategies that are applicable to todays classrooms where

    we are educating students for the 21stcentury.

    Life Support:There can never be adequate control of all variables such that what

    we see in a brain scan, brain wave, or genetic code can prove or predict exactly what a

    strategy or intervention will mean for individual students. By using my neuroscience

    background and classroom experience I offer interpretations of the research and

    correlations to teaching strategies that appear to have the strongest ties. As I share the

    stories of scientific validation of the wisdom of educational visionaries I hope to also

    illuminate the pathways through the brain that we see in science such as neuroimaging.

    This knowledge can guide us in planning instruction that coincides with the increased

    understanding of how the brain processes sensory input into learning and learning into

    wisdom.

    The purest truth I suggest is the least open to statistical analysis and comes not

    from my twenty years as a physician and a neuroscientist, but from my past ten years as a

    classroom teacher. There is no more critical life support and satisfaction than the breathof life and resuscitation of the joy of successful learning that passionate, informed

    teachers provide their students.

    The most surprising of all the connections I recognized between the science and

    the practice of teaching was the astonishing accuracy of the theories of the best

    educational and psychological visionaries coming from the accumulated scientific

    research over the past twenty years. The ideas of William James, Lev Vygotsky, John

    Dewey, followed by Steven Krashen, Howard Gardner, and others, are strikingly

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    consistent with what we are learning about the conditions most suitable for the brain to

    select which sensory input gains access to its neural circuitry, where that information

    goes, and how it influences our actions. This correlation also reminds me of the value of

    scientists heeding the observations of classroom teachers and their colleagues.

    Strategies can be deduced from correlations with research about the most suitable

    emotional, cognitive, and social environments, and effective methods of providinginformation through multisensory input, planning for individualization of achievable

    challenge, opportunities for inquiry, fostering of pattern recognition, and mental

    manipulation. When educators have opportunities to learn about the ways the brain

    processes, recognizes, remembers, and transfers information at the level of neural

    circuits, synapses, and neurotransmitters and share that knowledge with students, the

    empowerment for both enriches motivation, resilience, memory, and the joys of learning.

    Warning Label: Over the past two decades, the neuroscience of learning

    has been in almost constant transition. The union of mind, brain, and learning with

    laboratory and cognitive research is limited to suggesting strategies based on correlations

    and what I call neuro-logicalpredictions. By neuro-logical, I refer to strategies suggested

    by research that is consistent with my neuroscience background and my own, and others,

    classroom experiences.

    For example, neuroimaging can only demonstrate that brain activity is correlated

    with a cognitive task or influenced by variable presentations or emotional states.

    However, measurements of metabolic, electrical, or chemical activity in a region of the

    brain do not prove that the region or chemical is the direct cause of the behavioral

    outcome. To do that conclusively would require a lesion that disrupts the neural input to

    the brain region to which a cognitive activity is attributed. These lesion studies are being

    done in animal models, with techniques such as inducing electrical activity in the part of

    the brain with magnetic stimulation that disrupts localized regions of brain activity, butwe are not at the stage of safe lesion studies for human subjects (Poldrack & Wagner

    2004).

    Neuroimaging for education and learning research is still largely suggestive,

    rather than completely empirical, in establishing a solid link between how the brain learns

    and how it metabolizes oxygen or glucose. Teaching strategies derived from well-

    controlled neuroimaging are at best compatiblewith the research to date about how the

    brain seems to preferentially respond to the presentation of sensory stimuli.

    There are no formal guidelines to which researchers, curriculum publishers, or

    private educational consultants must adhere that restrict what they can claim are brain-

    based strategies. The status of the science of learning is still speculative because there

    are no infallible confirmations between neuroimaging, cognitive testing, strategies, andcompletely objective measurements of results. Even the most scrupulous researchers and

    clinicians cannot claim direct links from research to replicable results for individual

    students.

    It is up to professional educators possessing background knowledge about the

    brain to use the deductions of scientific research to guide the strategies, curriculum, and

    interventions they select for specific reasons and individual students. Knowing the

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    workings of the brain makes the strategies we already know more adaptable and

    applicable. We can be guided to use strategies that appear most consistent with the

    interpretations of the way the brain respond to stimuli during scientific studies and the

    long-term outcomes of these interventions.

    This evaluation of neuroscience data is achieved through the same process of

    transfer we strive to develop in our students. Just as we help them develop foundationalknowledge from which to construct conceptual understanding, so can we build an

    informed neuroscience background with which to evaluate and apply the information

    offered by the scientists of learning.

    Too Good to Be True is Sometimes True

    An advertisement in a national Sunday newspaper supplement recently offered a

    brain-energizing pill guaranteed to increase memory, mood, and motivation. As proof

    there were neuroimaging brain scans side by side. There were clearly the same image, but

    one had the contrast turned high to appear much brighter than the other. I would not

    expect any educators to be fooled by that. But, what if I offered you a neurochemical

    intervention to increase motivation, perseverance, creativity,.. and higher test scores in

    your students. Not for $100, or for ten easy payments of $8.99 plus tax and shipping. The

    price is telling a good joke and offering a choice of which test they take first.

    This chapter will describe the evolution of several current neuroscience to

    classroom topics in which the interpretations of the new sciences of learning correlate

    strongly with past predictions based on observation without benefit of looking into the

    brain. A look back and forward at the lab to classroom implications of attention, emotion,

    and neuroplasticity theories and research reveals the potential valuable, practical

    implications for instruction, curriculum (concepts), and assessment for todays learners

    tomorrows 21st century citizens.

    Neuroscience of Joyful Learning Emotion

    History Foretold: Remember, No smiles until after winter holidays. Recall the

    time when proper learning behavior was represented by students sitting quietly, doing

    exactly what they were told without question or discussion, and reporting back rote

    memorized facts on tests.

    Where did those notions come from? Certainly not the visionary educational

    theorists of the past. A few thousand years ago in 360 B.C., Plato advised against force

    feeding of facts to students without providing opportunities for them to relate learning to

    interest or evaluating their readiness.

    Calculation and geometry and all the other elements of instructionshould be

    presented to the mind in childhood; not, however, under any notion of forcing our system

    of education. Because a freeman ought not to be a slave in the acquisition of knowledge

    of any kind. Bodily exercise, when compulsory, does no harm to the body; but

    knowledge which is acquired under compulsion obtains no hold on the mind.(Plato, 387

    B.C.)

    Jump ahead several thousand years and we have Lev Vygotskys zone of

    proximal development theory that students learn best when guided the distance between

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    their level of independent problem solving and their level of potential development

    through problem solving under adult guidance, or in collaboration with more capable

    peers. (Vygotsky, L. (1978).

    Similarly, Steven Krashen supported the need for individualizing and

    differentiating instruction in the ZPD, which he called comprehensible input. Krashen

    also described the negative impact of stress on learning (Krashen, 1981). "Languageacquisition, first or second, occurs when comprehension of real messages occurs, and

    when the acquirer is not 'on the defensive'... Language acquisition does not require

    tedious drill. The best methods supply 'comprehensible input' (a bit beyond the acquirer's

    current level) in low anxiety situations, containing messages that students really want to

    hear. These methods do not force early production in the second language, but allow

    students to produce when they are 'ready', recognizing that improvement comes from

    supplying communicative and comprehensible input, and not from forcing and correcting

    production." Krashen, S. (1981).

    What Weve Learned

    The compelling nature of computer games is an excellent example of the success

    of differentiating instruction to students ZPD or level of comprehensible input. In a

    study of what makes computer games so captivating, variable player-ability-based

    challenge was interpreted to be the key element. The most popular computer games took

    players through increasingly challenging levels as they became more and more skillful.

    As skill improved, the next challenge would stimulate new mastery to just the right extent

    that the player could reach with practice and persistence (Malone 1981). This

    incremental, achievable challenge in the classroom, at the appropriate level for students

    abilities is motivating and strategically builds mastery by lowering the barrier not the bar.

    In the computer games, the level of challenge for each level of the game is such

    that the player is neither bored nor overwhelmed and frustrated. Practice opportunities

    allow the player to improve and experience the neurochemical response of pleasure whenthey succeed at the short-term goals that are provided by multiple levels of incremental

    challenge as they move to on the way to the longer-term goal of completing the game.

    This is the power of achievable challenge with opportunities for students to see their

    progressive improvement along the way to the ultimate goal, instead of only having the

    feedback of a test or other endpoint assessment. The computer game doesnt give prizes,

    money, or even pats on the back, yet it remains compelling because of the powerful brain

    response to intrinsic reward, as youll read regarding the dopamine effect in the next

    section.

    Before the research on the dopamine-reward system was done, it was Krashens

    theory of an affective filter that started my search for physical structures or neural

    networks that are influenced by stress. We have come to see how the brain literally filters(selects) the information that enters our neural networks and which networks (reactive or

    reflective) they enter, as well as the impact of stress and other emotions on these filters.

    Motivation, self-confidence, and anxiety all affect language acquisition, in effect

    raising or lowering the stickiness or penetration of any comprehensible input that is

    receivedA low or weak affective filter is needed to allow the input 'in'"(Krashen, 1981)

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    We now have the tools of the sciences of learning to support the

    recommendations to avoid forced instruction and incorporate appropriate environmental,

    social, emotional, and cognitive considerations in our instruction. Weve come a long

    way in the nature versus nature controversy. Where it was once believed to be genetics

    heavy hand predominantly determining intelligence limits, we now increasingly

    recognize the brains environmental responsiveness. Humans share all but 5-10% of thegenetic code with earthworms, which barely seems adequate to account for the physical

    and cognitive differences. Where once it was assumed that genes all expressed

    themselves, we now know that sections of many genes called alleles are turned on or off

    by environmental and social interactions (Lo, et al., 2003).

    Neuroimaging studies reflect the influence of stress and pleasure on the filtering

    of sensory input that enters the brain (Reticular Activating System), and the next filter

    (Amygdala Krashens Affective Filter) determines whether the information goes to the

    thinking brain (prefrontal cortex) or the lower, involuntary reactive brain. When stress

    directs sensory input to the lower brain, the input does not become consolidated as stored

    memory (Hippocampus and Prefrontal Cortex). The interpretation of scientific research

    supports interventions for emotional support, stress reduction, and strategies such as

    novelty, discovery, and conceptual learning that change the brains neurochemistry,

    processing of information, and construction of neural networks that hold information in

    memory.

    Beginning with the brains filters, this chapter extends to the research and

    classroom implications regarding strategies to influence the brains attentive focus,

    conduction of information to the prefrontal cortex, using the brains own

    neurotransmitters to facilitate learning, and concludes with interventions relevant to

    motivation and neuroplasticity.

    Intake Filters: The first such filter is the Reticular Activating System, a primitivenetwork of cells in the lower brainstem through which all sensory input must pass to

    reach any higher regions of the brain. All learning enters the brain through the senses.

    Much like other mammals, the human RAS favors intake of sights, sounds, smells, and

    tactile sensations that are most critical to survival of the animal and species. Priority goes

    to changes in an animal or humans environment that are appraised as threatening. When

    threat is perceived, the RAS automatically selects related sensory input and directs it to

    the lower, reactive brain where the involuntary response is fight, flight, or freeze (Raz &

    Buhle, 2006).

    The RAS is a virtual editor that grants attention and admission to a small fraction

    of all the available sights, sounds, and tactile sensations available at any moment. This

    survival directed filter is critical for animals in the wild, but as it has not changed

    significantly as man evolved, the implications for the classroom are significant. Reducing

    students perception of threat (punishment or embarrassment in front of classmates for

    not doing homework, fear that they will be picked last for a kickball game, or anxiety that

    they will make an obvious error because they are not fluent in English) is not a touchy-

    feely option. Unless the perception of threat is reduced, the brain persists in doing its

    primary job protecting the student or animal from harm. The neural activity on scans

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    during fear, sadness, or anger is evident in the lower brain, and the reflective, cognitive

    brain does not receive the sensory input not relative to survival even though that is the

    content of the days lesson (Shim, 2005).

    Neuroimaging has also given us information about which sensory input gets

    through the RAS when threat is not perceived. The RAS is particularly receptive to

    novelty and change that is associated with pleasure, color, and to sensory input aboutsomething that has aroused curiosity. Novelty, change, and other curiosity evoking events

    alert the RAS to pay attention (Wang, Wetmore, & Furlan, 2005).

    Students are criticized for not paying attention; they may just not have their RAS alerted

    to what their teachers think in important. Knowing about the RAS means we can promote

    classroom communities where students feel safe, where they can count of the adults in

    charge to enforce the rules that protect their bodies, property, and feelings from

    classmates or others who threaten these.

    Our increasing knowledge of what gains access through the RAS once threat is

    reduced also offers clues to strategies that promote attentive focus to our lessons (Raz and

    Buhle, 2006). Examples of building novelty into learning new information such as

    changes in voice, appearance, marking key points in color, variation in font size, hats,

    changes in seating arrangements, music, dance, photos, discrepant events, and radishes

    keep the RAS focused to admit sensory input!

    Advertising a coming unit with curiosity provoking posters or adding clues or

    puzzle pieces each day so students are invested in predicting what lesson might be

    coming gets the RAS primed to select the sensory input of that lesson when it is

    revealed (Perry, Hogan, & Marlin, 2000).

    Playing a song when students enter the room can also promote curiosity, hence

    focus, if they know that there will be a link between some words in the song and

    something in the lesson. If you behave in a novel manner, such as walking backwards, at

    the start of a lesson, the RAS will be primed by curiosity to follow along when you unrolla number line on the floor and begin a unit about negative numbers.

    Other RAS alerting strategies include engaging curiosity such as having students

    make predictions in discussions, KWL charts, and book previews. You can promote RAS

    admission to a lesson on estimating by overfilling a water glass and when students react,

    responding, I didnt estimate how much it would hold. Even a suspenseful pause in

    your speech before saying something particularly important builds anticipation as the

    students wonder what you will say or do next.

    If you think about the RAS as a gateway instead of just a filter, you can add your

    own creativity to any lesson without taking time away from teaching. Youll actually

    be accelerating the learning by increasing focus when your students want to know what

    you haveto teach. There may be several minutes of curious excitement when yourstudents enter the classroom and find a radish on each of their desks, but this time will be

    paid back literally with interest.

    Students RAS will be curious so their attention will promote sensory input

    clues to the puzzle of a novel object on their desks. They will be engaged and

    motivated to discover the reason the radishes are there. Younger students, learning the

    names and characteristics of shapes, now have the opportunity to develop a concept of

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    roundness and evaluate what qualities make some radishes have greater roundness than

    others.

    The lesson for older students might address a curriculum standard such as analysis

    of similarities and differences. The RAS will respond to the color, novelty, peer

    interaction of evaluating these objects, that are usually disdained when found in their

    salads, as they develop their skill of observation, comparison, contrast, and evenprediction as to why the radishes that seemed so similar at first, become unique as they

    become detectives using magnifying glasses. Students stress levels remain low as they

    use their individual learning strengths to sketch, verbally describe, or diagram on graphic

    organizers (such as Venn diagrams) and discover what the radishes in their group have in

    common and how they differ.

    As the survival tool, the RAS seeks pleasure, as animals have adapted to their

    environments and seek to repeat behaviors that are pleasurable and survival related, such

    as eating tasty food or following the scent of a potential mate. Engaged and focused

    brains are alert to sensory input that accompanies the pleasurable sensations. In animals

    these associations makes them more likely to find the source of pleasure in the future. As

    students enjoy the investigation with the radishes, the required lesson content can follow

    the open gateway to reach the higher, cognitive brain.

    The multisensory, novel experience has a greater chance of becoming long-term

    memory as the students are likely to actually answer parents often ignored queries about,

    What did you learn in school today? Students will summarize and mentally manipulate

    the days learning as grateful parents give the positive feedback of attentive listening. The

    impact of the radish as a novel object, and something theyd never expect to hear

    described by their child, now alerts their own RAS, and the stage is set for family

    discussion of the lesson beyond the doors of the classroom.

    Where Heart Meets MindThe portal to sensory input entering the brain is the RAS but, as we see on

    neuroimaging, the amygdala and associated neural networks function very much as

    Krashen described about the affective filter that reduces successful learning when

    students are stressed. Until recent neuroimaging provided data about real-time influences

    on the amygdala and surrounding components of the emotional networks in the limbic

    system, were thought to respond to danger, fear, or anger. As we now see on

    neuroimaging and measurement of neurotransmitter and cortisol levels, this system also

    responds to positive emotional influences.

    Experiments carried out while subjects were in the fMRI scanner involved a

    stressed and calm group. Subjects were shown a series of photographs of people with

    happy or grumpy expressions. These were not dramatic photos with laughing or furiousexpressions, but rather looked as people might at random walking down a busy street

    depending on their mood. After viewing the faces subjects were shown a list of words

    and instructed that the words would then appear mixed into a longer series of words. If

    they recognized a word from the initial list they were to respond with a clicker.

    The results on replicated tests revealed better recall in subjects who viewed the

    happy faces and their scans demonstrated a clear variation in metabolic activity. The

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    scans taken during their recall testing had higher activity in the prefrontal cortexes. It is in

    the prefrontal cortex (PFC) that neural networks converge that dominate in the regulation

    of our highest cognitive functions as well as executive functions (judgment, organization,

    prioritizing, risk-analysis, goal-directed behavior, critical analysis, concept development,

    conceptualization, knowledge transfer to creative problem solving), long-term memory

    construction, and emotional behavioral self-monitoring/control.Unlike the RAS, which is proportionately the same size in humans as other

    mammals, the PFC comprises the greatest proportional volume in the human brain. For

    voluntary learning to take place and memories stored the sensory input needs to pass

    through the RAS and be directed through the amygdala to the PFC.

    Subjects who viewed the grumpy faces showed metabolic activity high in the

    amygdalas, but significantly lower than the control group in their PFC while trying to

    recall the words they were instructed to remember. The significance of studies with

    varying sources of stressful variables replicated these findings that when in a negative

    emotional state, the metabolic brain activity is more prominent in the lower, reactive

    brain (fight/flight/freeze) (Pawlak, Magarinos, Melchor, McEwen, & Strickland, 2003).

    Just as Krashen predicted, there is an affective filter, but it is not just a block that

    closes access to the higher, reflective brain. The amygdala also has connections that

    expedite information flow to the reflective, voluntary, thinking prefrontal cortex. Seeing

    in these scans the response to facial expressions that we might ourselves manifest during

    the course of a school day, is a powerful illustration of the impact of emotion upon

    cognition.

    Before suggesting strategies that are neuro-logicalregarding the research on the

    amygdala, it is helpful to consider the chemical influences that are at work

    simultaneously in response to stress and pleasure. The example of the neurotransmitter

    dopamine is just one of dozens of neurochemicals and hormones that are coming to light

    as not only influencing learning, but also being activated by teaching strategies andenvironmental influences that activate or release these neuroactive substances.

    Dopamine one of many neurotransmitters that carries information across synapses

    between axons and dendrites of connecting neurons. Dopamine also has a more

    generalized influence on the brain. Dopamine release is associated with pleasurable

    experiences such that when dopamine is elevated we experience pleasure and when we

    use strategies or students participate in activities or reflections that are correlated with

    increasing dopamine release, the brain responds not only with pleasure, but also with

    increased focus, memory, and motivation (Stirn & Tecott, 2005). This makes sense going

    back to the survival benefits of pleasure and of animals remembering information that

    can result in pleasure attainment in the future.

    What Goes Up, Must Go Down even in the brain

    Just as dopamine levels rise in association with pleasure, a drop in dopamine can be

    associated with negative emotions. Unconsciously thenucleus accumbens, a dopamine

    storage organ located between each amygdala and the prefrontal cortex,releases more

    dopamine when ones prediction (answer) is correct and less dopamine when the brain

    becomes aware of a mistake (which actually takes place even before the person is

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    conscious of having made the incorrect prediction). As a result of the lowering of

    dopamine, pleasure drops after making an incorrect prediction. When a choice/answer is

    correct, the increase release of dopamine increases positive feelings (Salamone & Correa,

    2002).

    Dopamine is a learning friendly neurotransmitter. It is associated with pleasurable

    feelings, motivation, memory, and focus. The increased dopamine released from nucleusaccumbens (NAc), allows us to put positive value on actions or thoughts that resulted in

    the dopamine release (Galvan, Hare, Parra, Penn, Voss, Glover, & Casey, 2006).

    This is the dopamine-reward part of the system that relates to the compelling

    aspects of achievable challenge computer games. When players make progress toward the

    achievement of their goals and feel the pleasure the dopamine-reward they remain

    intrinsically motivated to persevere through the next challenges of the game (Gee, 2003).

    Similarly, when students experience the dopamine pleasure of a correct prediction in

    class, they are intrinsically motivated to similarly persevere through the challenges of the

    next level of learning ODoherty, 2004).

    The rise and fall of dopamine released from the NAc in response to the

    satisfaction of a correct choice (answer) is a way of reinforcing the memory of the

    information used to answer the question, make a correct prediction, or solve a problem.

    The brain favors and repeats actions that release more dopamine and the neural memory

    circuit becomes stronger and is used to make future successful choices.

    However, if the prediction is wrong, a drop in dopamine release from the NAc

    means there will be some degree of unpleasantness. The brain responds to this mistake

    negativity by altering the memory circuit to avoid repeating the mistake (Thorsten, et al,

    2008).

    The value of the brains dopamine disappointment response to mistakes is

    associated ht the brain changes through neuroplasticity. Changes in the neural circuits

    develop so the brain is more likely to make correct response the next time and avoid themistake negativity (van Duijvenvoorde, et al, 2008).

    The dopamine-pleasure modulating reward center in the nucleus accumbens

    (NAc) increases in reactivity through the teen years then settles down into adult pattern of

    less sudden, profound emotional shifts (Philpota, McQuona & Kirstein, 2001).

    The difference can be observed particularly in the prefrontal cortex areas of

    cognitive control. In children through age eight or nine, the reward center reacts strongly

    to positive feedback and minimally to negative feedback (Crone, et al, 2006).

    This is neuro-logical because young children (and baby animals) need to keep

    exploring to make sense of their worlds. In upper elementary school things begin to

    change and the prefrontal cortex is more negatively reactive to the drop in dopamine

    release by the NAc that occurs with mistake recognition. Thus students from about 6 thgrade through high school are impacted more by negative feedback and less by positive

    feedback.

    Reduce Fear of Mistakes

    Students greatest fear is making a mistake in front of the whole class, but

    learning increases with mistakes. In addition, Solving the problems of tomorrow will

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    require critical analysis, willingness to collaborate/tolerate, take prediction risks but

    analyze your options, and learn from mistakes. (McTighe, 2009) To construct and

    strengthen memory patterns (networks) of accurate responses and revise neural networks

    that hold incomplete or inaccurate information students need to participate predict

    correct or incorrect responses. The goal is to keep all students participating and engaged

    because only the person who THINKS, Learns.Only the students who risk making mistakes benefit from the nucleus accumbens

    and dopamine pleasure fluctuations. It is in response to the dopamine response to correct

    or incorrect predictions (answers) that increase brain receptivity to learning the correct

    response. This requires that immediate corrective feedback follow the students

    predictions.The brain motivation is to retain and reinforce the response that results in the

    pleasure or alter the incorrect information in the neural patterning network that resulted in

    the incorrect prediction and thus avoid the mistake negativity dopamine drop in the

    future. As will be discussed in the next section, this neural network strengthening or

    correcting are part of the processes of neuroplasticity

    Fear of risking mistakes reduces the active participation and construction of

    knowledge because the sensory input (instruction) cannot pass through the RAS and

    amygdala to the PFC. To keep stress low and information flowing to the reflective PFC,

    instead of the reactive, autonomic neural centers, students need to feel safe. We know

    from evaluation of effective teaching strategies, that frequent formative assessment and

    corrective feedback are powerful tools to promote long-term memory and develop the

    executive functions of reasoning and analysis. The frequency of assessment is critical so

    students dont become frustrated by confusion and drop into the fight/flight/freeze mode

    where learning cannot take place.

    For the process of assessment and expedient feedback to work, students must

    participate. The interventions are twofold. Keep the amygdala open to the PFC and

    reduce the fear of participation. When students are in this low stress state, they willparticipate and learn from feedback provided in a nontreatening manner. They will

    remain engaged in the lesson (Yaniv, Vouimba, Diamond & Richler-Levin, 2003).

    For the first goal, frequent individualized assessment throughout the class period

    can be done with anonymity. Ask frequent whole class questions with single word or

    multiple choice (by letter) answers and have students respond by writing on individual

    whiteboards. Students need only hold up their whiteboards long enough for you to see

    their responses and nod to signify youve seen them.

    Corrective feedback can follow after you tell the class the correct answer. These

    feedback interventions can be planned to coincide with syn-naps, my term for brain

    breaks. These syn-napsare needed to replenish neurotransmitters in the synapses that

    have been active in the neural networks engaged in the lesson activity. In this burnoutstate focus cant be maintained and the amygdala can begin to divert input to the lower,

    reactive brain instead of to the hippocampus and prefrontal cortex where new memories

    are created.

    During the syn-napsa change of pace, such as a dopamine boosting activity can

    continue the active learning, but does so using a different neural processing network.

    This is also a time when you can respond to the whiteboard assessments with appropriate

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    individualized corrective feedback for appropriate students, while others move up into

    their higher achievable challenge level, such as discussing a challenge question with a

    partner, creating a graphic organizer comparing the new material to prior knowledge, or

    predicting how what they learned can be transferred to other uses related to their

    interests.

    When the frequent whiteboard assessment/feedback process is a regular part ofyour class, the amygdala stressing frustration of confusion is reduced, because students

    know within a few minutes have help to acquire the understanding needed to proceed

    with their classmates. With the decrease in stress comes the lower likelihood of the brain

    diverting processing to the reactive networks. The classroom behavior problems of fight

    (acting out, disturbing others), flight (self stimulation and ADHD-like behaviors), or

    freeze (zoning out, losing focus) are reduced, as the filters are open to the reflective PFC

    instead of the reactive lower brain.

    Positivity

    Common stressors in the classroom include fear of being wrong, embarrassed

    about reading aloud, test-taking anxiety, physical differences, language limitations,

    negative peer relationships, cliques, frustration with difficult material, and boredom from

    lack of interest. You can set a positive emotional climate by being the solid force that

    keeps students feeling safe and the classroom community strong, thus lowering the stress

    that can block the flow of information into the thinking parts of the brain.

    When classroom learning environments are supportive and lessons tare engaging,

    personally meaningful, developmentally appropriate, and suitably differentiated to offer

    achievable challenge, students anxieties and participation reluctance can be replaced by

    confidence and their filters open to directing the information you teach to their prefrontal

    cortex.

    Strategies to promote input through the amygdala to the prefrontal cortex overlapwith those associated with increased brain levels of dopamine. Examples of these

    amygdala-friendly and dopamine boasting interventions include movement, being read

    to, intrinsic satisfaction such as achievement of meaningful goals, humor, optimism,

    positive peer interactions, and choice.

    Examples of incorporating these positivity influences in the classroom include

    pantomime or drawing sketches of vocabulary words, ball-toss to review high points of a

    lesson, well-planned collaborative group work, choice of practice or assessment options,

    and even sharing a humorous story.

    Achievable challenge and feedback that builds intrinsic motivation has a similar

    effect on the dopamine-reward circuit as the feeling of I get it that accompanies the

    understanding of a subtle humor, such as a Gary Larson cartoon. This feeling of self

    recognition and the associated increase in dopamine pleasure can lead to a more positive

    attitude toward challenging academics. Using discovery and inquiry-based learning can

    also result in these positive brain responses that build the foundations of long-term goal

    development and self-directed learners.

    Mind Controls Matter as Intelligence Can be Changed

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    The greatest positivity building tool comes from students learning about their

    brains ability to change itself through its interaction with the environment. The ultimate

    benefit of mistake negativity and dopamine reward are manifested by the altering of the

    brains neural networks. It is within these networks of connecting neurons that

    information is stored, transported, and organized. Neuroplasticity is the ability of these

    networks to transform based on the acquisition of new information, recognition ofassociations between new and prior knowledge, and the reorganization, extension,

    correction, and strengthening that takes place.

    When students understand that their brains have the capacity to develop stronger,

    more efficient, accessible, and durable neural networks through their actions, they have

    the positivity, resilience, and motivation to do their part to develop the skills, knowledge,

    and intelligence to achieve their goals.

    Scientists are certainly on to something regarding neuroplasticity and I enjoy

    reading current day claims to both the terminology and the concept of neuroplasticity. Id

    split my vote between these discriptions of our ability to change our brains and change

    our intelligence.

    Organic matter, especially nervous tissue, seems endowed with a very

    extraordinary degree ofplasticity...A path once traversed by a nerve-current might be

    expected to follow the law of most of the paths we know, and to be scooped out and

    made more permeable than before with each new passage of the current. The scientist

    goes on to describe this response of brain tissue to repeated stimulation as forming a path

    that becomes more embedded with repeated use (James, 1890).

    Regarding our brains ability to develop intelligence through effort and active

    mental manipulation, studying has been described as mental exercise comparable to

    gymnastic practice If he holds no conversation with the Muses, does not even that

    intelligence which there may be in him, having no taste of any sort of learning or inquiry

    his mind never waking up or receiving nourishmentWe must watch them from theiryouth upwards sustaining reason with noble words and lessonsso they toll at

    learningto reach the highest knowledge. (Plato, 387 B.C.).

    Neuroplasticity describes the phenomenon the development and strengthening of

    neural networks (more synapses, dendrites, greater genetic production of protein in the

    neuron, and layers of insulating myelin around axons). This construction of stronger,

    more efficient (faster retrievable, greater transfer) networks of long-term memory is

    stimulated by repeated activation of the circuit such that practice makes permanent

    (Rivera, Reiss, Eckert & Manon 2005).

    An example of the neuroplasticity phenomenon comes from an experiment

    studying the visual cortex. When we see, the information reaches the cortex of the

    occipital lobes. When we feel something that sensation is recognized and interpreted bythe parietal lobes. However, when subjects were blindfolded for a week and received

    intense Braille practice, which is tactile-sensory, their occipital cortex, which before the

    experiment did not respond to tactile stimuli, demonstrated new neural circuit plasticity

    and fMRI activity. Their response as similar to the visual cortex in people blind from

    birth (Theoret, Merabet, & Pascual-Leone, 2008).

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    Pattern Development for More Successful Prediction (Correct Answers)

    The extension and modification of neural network connections follows the patterning

    theories described by Piaget (Ginsberg & Opper, 1988).

    When students knowledge increases through pattern recognition and matching

    new information to existing stored related memories, the neural networks become more

    extensive and knowledge grows. Further modification, correction, and strengthening ofthe networks is stimulated by dopamine level feedback through the nucleus accumbens

    reward/negativity response.

    Mental manipulation or exercising the neural networks holding the related

    information takes place each time students participate in the mental or physical endeavor

    such that the specific pathway of neurons is activated and their connections strengthened.

    Through neuroplastisity, the brain is changed by experience, environment and effort

    (Dragansk & Gaser, 2004).

    Patterning and Memory:To survive successfully animals need to understand

    their environments and make meaningof what they see, hear, smell, and touch all around

    them. The brain is designed toperceive and generate patternsand uses these patterns to

    predict the correct response/decision/behavior/answer to new information.

    Patterning refers to the meaningful organization and categorization of

    information. Sensory data that passes through the brain's filters needs to be successfully

    encoded into patterns that can be connected to existing neuronal pathways. Patterning is

    the brain process of structuring information received through the senses (sensory data

    input) into the format or coding by which it travels from brain cell to brain cell. In

    response to sensory input, our brains build new connections and stimulate existing neural

    networks by detecting patterns and evaluating new stimuli for clues that help us connect

    incoming information with stored patterns, existing categories of data, or past

    experiences and thereby extend existing patterns of stored information with the new

    input.When sensory input first reaches the hippocampus, just beyond the amygdala, it is

    available only to working memory(short-term memory). The hippocampus takes sensory

    inputs and integrates them with relational or associational patterns. This binds the new

    information with already stored and patterned information and builds long-term relational

    memories. This is the memory of what you think you need now and fades in less than

    minute.

    Working memory has limited capacity, usually about 5-9 items such as a

    telephone number, so as new input comes in, others drop out. The brain responds to new

    working memory by scanning memory stores for patterns of prior memories that might be

    related to the new input. When new input connects with a previously stored memory the

    dendrites connect in new pattern sequences and the new relational memory is integrated

    into neuronal memory networks with previously stored memories. When either fact is

    later recalled or prompted, the patterned integration or association that was created

    activates the related memory (Davachi & Wagner, 2002; Eldridge, Engel, Zeineh, &

    Knowlton, 2005).

    Connect With Prior Knowledge: Help students relate the new information with

    data they have already acquired through personal experience or real world associations.

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    Relational memory consolidation can be promoted by activities that help students see the

    patterns and connections between what they know and what they are learning. Graphic

    organizers, analogies, recognition of similarities and differences promote this patterning

    and extended growth of the interneural connections.

    Whenever new material is presented in such a way that students see relationships,

    they generate greater brain cell activity (forming new neural connections) and achievemore successful long-term memory storage and retrieval. Activating prior knowledge can

    also be promoted with KWL brainstoming, preunit assessment, videos, class discussion

    using current events of high interest to the students, and relating the unit to prior

    knowledge with ball toss or discussions about what they learned about the topic from the

    perspective of another class (especially if there is cross curricular planning).

    Patterns connect new to prior experience, and prior experience provides reference

    points for constructing new understanding and predicting the correct response to new

    information. Patterns are paths for memories to follow. Education is about increasing the

    patterns that students can use, recognize, and communicate. As the ability to see and

    work with patterns expands, their ability to take in more associated information and make

    better predictions is reflected in their long-term memory, concept formation, retrieval of

    stored information, and transfer of learning from its original context to other uses.

    executive functions are enhanced.

    Younger students benefit from activities that build their pattern recognition skills.

    Students can guess the pattern you are using as you call up students with a similar

    characteristic such as blue shirts. You can give examples and non-examples of a concept

    (such as past tense and present tense) and students make silent independent predictions as

    to what category or concept the items share.

    Graphic Organizers to Pattern: Graphic organizers with visual, diagrammatic,

    pictorial, or graphical ways to organize information and ideas for understanding,

    remembering, or before writing a paper. For the most part, the information on a graphicorganizer could be written as a list or outline, but graphic organizers give students

    another way to see and mentally, as well as visually and kinesthetically, manipulate the

    information.

    Graphic organizers allow students to create visual pictures of information in

    which their brains discover patterns and relationships. When the brain can find and

    interpret information as a pattern, such as in a graphic organizer, it receives the

    information as meaningful input for memory storage.

    Multisensory Learning for Pattern Extension: Greater brain region stimulation

    promotes the growth more connections between synapses and dendrites and more

    myelination. In multisensory learning there is repeated stimulation of more areas of the

    brain as information is presented through multiplesenses. Presenting information in a

    variety of ways makes the input more likely to resonate with prior knowledge stored in

    existing categories and patterns of memories in multiple sensory cortex regions. In this

    way, multiple brain regions are connected to the activity or lesson because each of the

    senses has a separate storage area in the brain. (Wagner, Schacter, Rotte, Koutstaal,

    Maril, Dale, Rosen, Buckner, 1998).

    Multisensory learning increases the efficiency of memory retrieval as activation

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    of one area of the memory storage, such as the visual cortex, simultaneously activates

    other cortical regions where the memory was stored (such as when it is also learned

    through auditory input (temporal lobe) physical movement (cerebellum and basal

    ganglion) (Rivera, Reiss, Eckert, & Menon, 2005).

    Duplicated storage areas also result in faster, more accurate recall because stored

    memories can be retrieved by a variety of cues. Activities that allow students to use avariety of their senses can make the difference between engagement and frustration.

    Further exercise and neuroplastic extension of these networks is consistent with

    the recommendations of another pioneer of educational theory, Benjamin Bloom. His

    recommendations included extending thinking beyond isolated facts into integrated

    concepts using analysis, synthesis, and evaluation to build intelligence (Bloom, 1956).

    When learning goes beyond rote memorization of isolated facts and students have

    opportunities to construct knowledge through experiences of prediction, evaluation, and

    discovery, the dopamine-reward/negativity circuit provides feedback that revises,

    extends, and strengthens the neural networks into concepts. As new information is

    recognized as related to prior knowledge already existing within the patterned categories

    of neural networks, learning extends beyond the domain in which it took place and is

    available for transfer creative new predictions and solutions to problems in other areas

    beyond the classroom or test. In other words, intelligence grows.

    Yes You CanChange Your Intelligence

    Through mental scanning, activation of multiple memory storage areas in

    previously constructed neural circuits (pattern) provides as templates upon which to

    encode and attach the new sensory input. As students grow and learn, they continue to

    expand their experiential database. The more experiences they have, the more likely their

    brains are to find a fit when they compare new experiences with previous ones.

    Intelligence can be considered a measure of students ability to make accurateconnections of new input with existing patterns in their neural networks of stored

    information. These connections allow them to acquire and apply the new knowledge to

    solve problems such that more successful, extensive patterning leads to more accurate

    predictions (answers).

    Children, as well as many adults, mistakenly think that intelligence is determined

    at or before birth by their genes and that effort will not significantly change their

    potential for academic success. Especially when students believe they are not smart and

    nothing they do can change that, the realization that they can literally change their brains

    through study and review strategies is empowering. This is also true of my neurology

    patients who lose function due to brain disease or trauma and through practice beginning

    with visualizing of moving the paralyzed limb or imagining themselves speaking,neuroplasticity constructs new neural networks as undamaged parts of their brains take

    over the job of the brain damaged regions.

    Students and patients are motivated to take action when they learn about

    neuroplasticity, see brain scan evidence of brain changes, and see the results of their own

    actions when, with more and more practice, neurons that fire together, wire together,

    stimulating their neural circuits and making them stronger.

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    As described in the Brain Owners Manual I created for educators, I explain to my

    students, Your own mental efforts in all types of executive function (higher thinking)

    such as delaying immediate gratification, working to achieve goals, and evaluating the

    strategies you used when you were most successful actually build your brain into a more

    efficient and successful tool that you control.

    You become the sculptor of your brains PFC nerve circuits that focus yourattention, retain information in long-term memory, and retrieve the stored knowledge you

    need to solve new problems in your academic and emotional life. There is strong overlap

    in the PFC networks of emotional control and intelligent thinking. As you exercise

    (stimulate) these networks youll find that when you stop to evaluate your emotional

    feelings the way you analyze problems in math or skills in soccer, your stronger PFC

    nerve circuits will better enable you to manage frustration, confusion, or boredom instead

    of these feelings controlling you.

    I have been teaching my upper elementary and middle school students about the

    brain filters that determine what information reaches their higher, thinking brains

    (prefrontal cortex) and how they can consciously influence those filters. They learn about

    changes in their brains that take place through neuroplasticity. I show them brain scans,

    and we draw diagrams and clay models of connections between neurons that grow when

    new information is learned. I call their summaries of lessons Dend-Writes and we

    discuss how more dendrites grow when information is reviewed and they have adequate

    sleep. I even send home electron microscope photos of growing dendrites and synapses

    and assign students to explain that neuroanatomy to family members and report their

    responses.

    Their results are wonderful. One ten-year-old boy said, I didnt know that I could

    grow my brain. Now I know about growing dendrites when I study and get a good night

    sleep. Now when I think about playing video games or reviewing my notes I tell myself

    that I have the power to grow brain cells if I review. Id still rather play the games, but Ido the review because I want my brain to grow smarter. It is already working and feels

    really good.

    I use sports, dance, and musical instrument analogies about building greater skill

    the more students practice a basketball shot and ask them to recall how their guitar or

    ballet performances improved the more they rehearsed. Then we make connections to

    explain that their brains respond the same way when they practice their multiplication

    facts or reread confusing parts of a book, because through neuroplasticity - practice

    makes permanent.

    The Future

    The most rewarding jobs of the 21stcentury will be those that cannot be done bycomputers. The students best prepared for these opportunities, as well as the

    responsibilities of solving problems that havent even been recognized yet, will need a

    skill set far beyond the current subject matter and procedures evaluated on standardized

    tests. The qualifications for success in the world todays students will enter will demand

    the abilities to think critically, communicate clearly, utilize continually changing

    technology, be culturally aware and adaptive with the judgment and open-mindedness to

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    make decisions based on foundational and conceptual knowledge using their high order

    executive functions for accurate analysis of information. They will need these skills to

    succeed as creative, collaborative problem solvers in the world they inherit. The keys to

    the success of todays students are coming through the collaboration of the laboratory

    scientist and the classroom teacher.

    The Science: Neuroscience is showing us more of the brains potential to changeintelligence through neuroplasticity. With increasing developments in genetic analysis

    and fMRI scanning, we will continue to add to understanding of how different people

    learn and the role of environment and experience. We will have more predictive

    information earlier to individualize learning for each student. As our knowledge of the

    brain improves with better understanding of its information processing functions,

    neurotransmitters, and localization of what parts do what, well know more about the

    strategies best suited for different types of instruction.

    Technology will surely play an increasing part in the classrooms of tomorrow.

    Just as more on-line classes and computerized instruction, especially for foundational

    knowledge at all grade levels, are already in use, the possibilities for the future are almost

    infinite. Models are developing to use neuroimaging, EEG, and cognitive evaluations to

    predict the best instructional modes for individual students.

    As we have gained greater understanding of brain dysfunction and early

    intervention for problems from dyslexia to autism, there are even suggestions for social

    robots. For example, mirror neuron research suggests that the same regions of the brain

    that are active when an action is carried out are also activated earlier during the learning

    process (Rizzolati & Craghero, 2004).

    A theory is that when a young child sees an adult moving the mouth in

    vocalization or displaying facial expressions related to emotions, the mirror neurons in

    the child activated in response are starting construction of the neural networks that will

    subsequently direct those same actions (Bastiaansen, Thious, & Keysers, 2009).Further investigation of teaching application of mirror neurons and the role of

    imitation is already funded by the NSF to evaluate the use of social robots to promote

    social interaction skills in children. The research team foresees a place for these social

    robots to personalized, individualized environment for each student (Littlewort, 2004).

    Collaboration: An equally exciting trend is the development of learning

    communities within schools or districts where classroom teachers, resource specialists,

    and administrators use books, videos, and sharing of professional development

    workshops attended to evaluate possible interventions appropriate to their students

    needs. These educators who teach and observe classrooms discuss successful strategies

    and use the knowledge the acquire about the science of learning to further improve the

    interventions and transfer their observations and assessments to other lessons or age

    groups.

    The interface of science and learning can continue to guide educators in the

    development of the strategies, interventions, and assessments to prepare todays students

    for the world of tomorrow. A so what of educators learning about brain function and

    structure starts with knowing why a strategy works. The more educators know about the

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    research-supported basis for a strategy or procedure, the more they feel invested in it and

    the more comfortable they are using and modifying the strategy. This empowers and

    encourages teachers to extend lessons beyond rote memory into conceptual

    understanding, transferable knowledge, and help students become life-long learners

    because they are embraced by neuroscience of joyful learning. With the collaboration of

    neuroscientists, cognitive psychologists, educators, and other specialists, teachers willhave opportunities to reconnect with the resourcefulness, compassion, and creativity that

    motivated the choice of a career in education.

    Collaboration is what will propel the next educational advancements of the 21st

    century. The one-way street of scientists telling teachers what to do, without spending

    time in classrooms, has been modernized to a bridge between classroom and laboratory.

    The future developments with the most extensive and useful classroom applications will

    likely arise from input from educators to scientists.

    The increased access from educator to research planning opens the way for

    investigation of success so what goes rightcan be evaluated by the researchers to gain

    understanding into the neurological and cognitive brain processing involved in the

    successful strategies. This exchange is even now taking place through organizations such

    as International Mind, Brain, and Education Society (IMBES) and Harvard's Mind, Brain,

    and Education (MBE) program. Program director, Dr. Kurt Fischer sees movement

    toward increasing integration of neuroscience and cognitive science with education to

    further the interdisciplinary progress of improving successful learning for all students.

    Through collaboration between educators and scientists, the seeds planted in a

    single classroom by a creative, resourceful teacher could be analyzed, replicated,

    expanded, and disseminated to benefit students worldwide.

    After all, isnt sharingwhat we teachers do so well.

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