Upload
kory-ferguson
View
214
Download
0
Tags:
Embed Size (px)
Citation preview
Current Areas of Space-Related Health Research
• Role of oxidative stress in– Cancer– Cataracts
• Bone loss– Vitamin D, calcium, vitamin K– Non weight-bearing exercise to sustain bone
health• Melatonin and sleep cycle regulation
Presenter: Paul M. Coates
Agency/Organization: NIH Office of Dietary Supplements
Promising Areas for Space-Related Health Research Collaborations
• Dose-response studies of vitamin D and calcium in maintaining bone health
• Mechanisms to protect against free radical damage to lens proteins
Existing Resources to Facilitate Space-Related Health Research
• NIH Botanical Research Centers Program– Purdue University-University of Alabama at Birmingham
• Project: Polyphenols, singlet oxygen and protein damage in the eye (Stephen Barnes, Ph.D. and Om Srivastava, Ph.D.)
The ICR/f rat - model for lens cataractsSprague-Dawley Rat
ICR/f Rat
A colony of ICR/f rats has been established at UAB
Lens cataracts in ICR/f rats
Nuclear, matureCortical, early Cortical, mature