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CURICULUM VITAE
(Updated 1/1/2014)
Prof. Mokhtar Mostafa Mohamad TahaCoordinator of International Relations
Assiut UniversityEgypt
Dr. Mokhtar Mostafa Mohamad Taha, Ph.DName
2
MaleGender
1/1/1955Date of BirthAssiut/EgyptPlace of Birth
MarriedSocial StatusMoslemReligion
Professor of pathology &
Coordinator of International Relations, Assiut University
Title
Anatomic PathologyGeneral Specialization
Molecular OncologySubspecialityDept. of Pathology& Clinical Pathology
Faculty of Vet. Medicine
Assiut University
Assiut, Egypt
Permanent Work Address
002- 088/2314633 (Home)
002/01098186919 (Mobile)
002/088/2411632 (Work)
Tel. Nos:
002/088/2354130) Assiut/Egypt (Fax No:
Qualifications
1 - B.S. degree in Vet. Med. Sciences, May 1977 with grade “Very Good”. Fac.
of Vet. Med., Assiut University, Egypt.
2 - Master degree in Pathology of Infectious Diseases, Fac. of Vet. Med.,
Assiut Univ., Egypt 1981.
Title of Thesis: Some Studies on Experimental Infection of C. ovis in
Buffaloe Calves.
3 - Ph.D. degree in Oncopathology, Fac. of Vet. Med., Assiut Univ., Egypt,
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1984.
Title of Thesis: Immunohistochemical Studies on Experimental Mammary
Carcinogenesis In Rats. Effect of BCG Vaccine.
Professional BackgroundCoordinator of International Relations of Assiut
University, Egypt.
2013 -present
Prof. of Anatomic Pathology, Fac. of Vet. Med., Assiut
University, Egypt.
2012 -present
Professor of Anatomic Pathology, Dept. of Pathology,
College of Medicine, King Khalid University, Abha, KSA
2006 -2012
Director of the Molecular Biology Research Unit, Assiut
University, Egypt.
1998 -2006
Prof. of Anatomic Pathology, Fac. of Vet. Med., Assiut
University, Egypt.
1994 -present
Assistant Professor of Anatomic Pathology , Fac. of Vet.
Med., Assiut University, Egypt.
1989-1994
Lecturer of Anatomic Pathology , Fac. of Vet. Med.,
Assiut University, Egypt.
1984-1989
Assistant Lecturer, Dept. of Pathology, Fac. of Vet.
Med., Assiut University, Egypt.
1981-1984
Demonstrator, Dept. of Pathology, Fac. of Vet. Med.,
Assiut University, Egypt.
1977-1981
Fellowships & AwardsAttached to the Department of Pathology, College of
medicine, King Khaled University, Abha, KSA.
1/9/2006 -1 /9/2012
DAAD scholarship to the Dept. of Neurology, Technical
University of Dresden, Germany.
19/7/2005- 19/9/2005
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Tempus Individual Mobility Research Grant carried out
at the Queen's University of Belfast, Royal Victoria
Hospital, and Department of Surgery and applied
Clinical Sciences, N. Ireland.
22/7/2003- 12/9/2003
DAAD scholarship to the Institute fur Veterinar-
Pathologie der Justus- Liebig- Universitat Giessen,
Germany.
15/6/2001- 15/9/2001
Visiting Professor to the Dept. of Immunology &
Preclinical Science, Fac. of Vet. Med. Science,
University of Liverpool, UK.
1994 -1996
Fellowship awarded by the Dept. of Hematology, M.D.
Andreson Cancer Center, Texas medical Center,
Houston, Tx, USA.
28/7/1987- 26/6/1988
Peace fellowship affiliated by the Egyptian Government
to the Dept. of Cell Biology, Baylor College of Medicine,
Texas medical Center, Houston, Tx, USA.
29/6/1986- 27/4/1987
Memberships1 -Scientific committee for promotion of professors and assistant professors in
Veterinary Pathology.
1 -Editorial board of Assiut Veterinary Medical Journal.
2 -Center of public services, Fac. of Vet. Medicine of Assiut University.
3 -Council of Fac. of Vet. Medicine of Assiut University.
4 -Council of dept. of Pathology and Clinical Pathology, Fac. of Vet. Medicine
of Assiut University.
5- Egyptian Vet. Medical syndicate.
6- Egyptian Vet. Medical Association for Pathology and Clinical Pathology.
7 -Scientific research committee, College of Medicine, King Khaled University,
Abha, KSA.
Conferences and Workshops AttendedXVIth International Congress on Animal Hygiene, 5-9 May, 2013
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Nanjinj, China.
The 8th Annual Research day, College of Medicine, King
Khaled University, Abha, KSA.
May, 2012
Workshop on: A Galaxy of Online Learning Style and
Learner-centered Examples. E- Learning Center, King
Khaled University, Abha, KSA.
2nd Feb., 2009
th Annual Research day, College of Medicine, King
Khaled University, Abha, KSA.
28th May, 2008
Workshop on: Small Group Teaching organized by
Medical Education Development Center, King Khaled
University, Abha, KSA.
17th May, 2007
Workshop on: The Liver from Embryology to Adult
Pathology. Accredited by The Saudi Commision for
Health Specialists, King Khaled University, Abha, KSA.
1st May, 2007
The 9th Saudi Gastroentrology Association Conference,
College of Medicine, King Khaled University, Abha, KSA.
7-10 May, 2007
The 20th meeting of the European Society of Veterinary
Pathology, Grugliasco (Turin), Italy.
18-21 Sept., 2002
The 18th meeting of the European Society of Veterinary
Pathology, Amsterdam, The Netherland.
19-22 Sept., 2000
The IFSTP International Symposium in Cambridge, UK1998
The 11th San Antonio Breast Cancer Symposium, USA.29-30 November, 1988
International Breast Cancer Conference, Miami, Florida,
USA.
1986
All the national conferences organized by the Fac. of
Vet. Medicine of Assiut University, Egypt.
1984 -present
Research Projects Carried Out AbroadUSA:
1 - From 1986 to 1987: I was involved with Prof. Dr. Daniel Medina at Baylor
College of Medicine, Houston, Texas, USA in a research project dealt with the
use of polyclonal and monoclonal antibodies to characterize
immunohistochemically normal and preneoplastic mammary tissue. We used
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a wide variety of fixation protocols as well as antibodies to cell surface and
cytoskeletal proteins.
2 - From 1987 to 1988: I had been working with Prof. Dr. Gary Spitzer at M.D.
Andreson Cancer Center, Houston, Texas, USA. I was a project investigator
for screening of bone marrow for isolated epithelial tumor cells not detected
by classical methodology in breast cancer patients (bilateral bone marrow
biopsies and aspirates). We screened a large panel of monoclonal antibodies
to supplement the use of anticytokeratins antibodies. We developed an
immunohistochemical method, which showed no cross-reactivity or
background staining with normal bone marrow.
UK:
1- From 1994 to 1996: I was involved with Dr. Stuart Carter of the Vet. Med.
Science, Univ. of Liverpool, UK in a research project dealt with the
immunohistochemical characterization of the infiltrating T-lymphocytic series
in the joints of dogs affected with chronic rheumatoid arthritis.
2 - From 7/ 2003 to 9/ 2003: I was involved with Prof. C. Campbell and Dr. M.
El- Tanani at the Queen, s University of Belfast, NI, in a research project
aimed to define genes that might be associated with breast cancer
metastasis. In vivo studies were carried out using specimens from breast
cancer patients with follow up history. Osteopontin gene (OPN) was detected
in samples of primary breast carcinomas from a comparatively large group of
patients to assess its relationship with other potential prognostic factors like
estrogen and progesterone receptors and their association with patient death
from metastatic disease. Parallel in vitro studies were also done using
different mammalian cell lines like Rama37 and MCF- 7.
Germany:
1- From15/6/2001 to 15/9/2001: I was involved with Prof. Manfred Rienachar,
Institute fur Veterinar- Pathologie der Justus- Liebig- Universitat Giessen,
Germany, in a research project on human papillpma virus (HPV).
2- From 19/7/2005 to 19/9/2005: I was involved with Dr. Gille of the Neurology
Dept., Technical University of Dresden, Germany in a research project that
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dealt with studying the effect of some neuroprotective drugs on the
dopaminergic neurons of Parkinsonian patients.
Current Research Projects
We are investigating the clinical applications of nanoparticles for treating of
some medical problems in experimental animals. Currently we study the
therapeutic effect of melatonin loaded nanovehicles for treating acute and
chronic gastrodudenal ulcers in mice by histopathological, biochemical and
molecular technicques.
Teaching ActivitiesIn College of Medicine, King Khaled University, Abha, KSA: 1-Teaching and coordinating general pathology course (Path333) for level 5
medical students.
2- Teaching systemic pathology course (Path 335) for level 6 medical
students.
3- Teaching and coordinating pathology course (Path 332) for level 5
dentistry students, College of dentistry.
4-Teaching and coordinating pathology course for level 6 laboratory medical
students, College of laboratory medical sciences.
5-Teaching molecular medicine for level 10, medical students.
Other Activities in King Khalid University, Abha, KSA:
- Establishing of Molecular Pathology unit in the department of Pathology,
College of Medicine, King Khalid University, Abha, KSA.
- Establishing of a program for Master of Applied Research in Pathology
(MSc. Res. Path) in the Dept. of Pathology, College of Med., King Khalid
University, Abha, KSA. This program has been evaluated and approved.
In Assiut University, Egypt:
1- Teaching of theoretical and practical classes of pathology for level 3 and 4,
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veterinary medical students, Fac. Vet. Medicine, Assiut Univ., Egypt.
2- Teaching of molecular pathology courses for postgraduate medical
students as a prerequisite to master and PhD degrees, Fac. of Medicine and
Vet. Medicine, Assiut University, Egypt.
Other Activities as a Director of The Molecular Biology Unit of Assiut University, Egypt for the period 1998- 2006:
- I have obtained a grant from the Higher Egyptian Education Project Fund
(HEEPF) to organize a series of training workshops for all medical
postgraduates and university staff in the field of molecular biology and tissue
culture as listed below:
PCR workshops:1 -Basic Principles and Techniques of PCR (Level I).
2 -Advanced Theoretical and Practical Topics on PCR (Level II).
3 -Principles and Application of Real-Time PCR.
4 -Basic Principles and Laboratory Techniques on DNA Cloning.
Cell culture workshops:
1 -Theoretical and Practical Basis of Neuronal Cell Culture.
2 -Theoretical and Practical Approach for Primary Hepatocyte Cell Culture.
3 -Cell Line Tissue Culture: Theoretical and Practical Approach for Application
in Molecular Biology.
Protein workshops:1 -Principles of Basic Protein and Immunoblotting Techniques (Level I).
2 -Advanced Techniques on Protein and Their Applications (Level II).
- Joint research projects for master and PhD degrees in the faculty of
medicine, vet. Medicine, science and agriculture, Assiut university, Egypt. .
- International collaboration with professors from Germany and Vienna for
organizing joint workshops in the unit.
- Diagnosing diseases using molecular biology tools for patients of upper
Egyptian governorates. Example HCV.
- Introducing postgraduate courses in molecular biology, protein biology and
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tissue culture techniques in the curriculum for medical students.
Supervision of Master Thesis: 1- Master thesis entitled: Some studies on targeted therapy for gastric ulcers
(recent registration, 2014).
2- Pathological evaluation of environmental pollution with fluorine and
cadmium emitted by Manqabad superphosphate factory on goats (2006).
3 - Master degree entitled: Pathological studies on Aflatoxicosis in mice:
Effect of antioxidants. (2004).
4 - Master degree entitled: Bone marrow and blood immunohistochemical
studies in experimentally induced leukemia in rat (1996).
5 - Master degree entitled: Clinicopathological studies of renal affections in
rabbits (1992).
Supervision of Ph. D. Thesis:1- PhD thesis entitled: Pathomorphological studies on Fasciola infection with
a special reference to its control (2008).
2- PhD thesis entitles: Morphopathological studies on the female genital
system of infertile buffalo cows (2006).
3 - PhD thesis entitled: Assessment of some meat products for the
occurrence of Escherichia coli 0157:H7. (2005).
4- PhD thesis entitled: Prophylactic and therapeutic effects of melatonin
on Parkinson- like syndrome induced by MPTP neurotoxicity in mice.
(2002).
5- PhD thesis entitled: Avian ascitis syndrome: experimental study
(1997).
List of Publications Submitted by Prof. Mokhtar Taha
A: Papers published in international journals
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1- Refaat Ali Eid, Mokhtar Taha and Yasmin Omar El-Amir (2013): Histopathological and ultrastructural studies on human cutaneous
leishmaniasis. Comp Clin Pathol DOI 10.1007/s00580-013-1793-6 Received:
13 March 2013 /Accepted: 31 July 2013
Springer-Verlag London 2013
2- Mahmoud A., Mokhtar Taha, salah H. Afifi, Khaled M.A. Hassanien and
Amal Mohamed Abdo (2010): Drug resistance and recent therapeutic
measures in controlling of fascioliasis. Journal of American Science, 6(11),
926-933.
3- Khaled Radad, Rudolf Moldzio, Mokhtar Taha and Wolf-Dieter Rausch
(2008): Thymoquinone protects dopaminergic neurons against MPP+ and
rotenone. Phytother. Res. Published online in Wiley InterScience
(www.interscience.wiley.com) DOI: 10.1002/ptr.2708.
4-Taha, M.; Ordonez, N.G.; Kulkarni, S.; Owen, M.; Hortobagyi, G.; Reading,
C.L.; Dicke, K.A. and Spitzer, G. (1989): A monoclonal antibody cocktail for
detection of micrometastatic tumor cells in the bone marrow of breast cancer
patients. Bone Marrow Transplantation, 4: 297-303.
5- Kulkarni, S.S.; Wang, Z.; Spitzer, G.; Taha, M.; Hamada, T.T. and Dicke,
C. (1989): Elimination of drug- resistant tumor cell lines by monoclonal anti- p-
glycoprotein antibody and rabbit complement. Blood, Vol. 74, No. 6: 2244-
2251.
6-Campbell, S.M.; Taha, M.; Medina, D. and Rosen, J.M. (1988): A clonal
derivaive of mammary epithelial cell line COMMA-D retain stem cell
characteristics of unique morphological and functional heterogeneity. Exp.
Cell Res., 177: 109-121.
7-Medina, D.; Schwartz, M.; Taha, M.; Obron, C.J. and Smith, G.H. (1987):
Expression of differentiation-specific proteins in preneoplastic mammary
tissues in BALB/c mice. Cancer Res., 47: 4686-4693.
8-Youssef, H.A.; El-Sebair, A.; Taha, M. and Makady, F. (1987):
Lymphosarcoma in a single-humped Camel. 23rd World Veterinary Congress,
Montreal Canada. Offprint from “Veterinary Medical Review” No. 1, PP. 68-71.
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B- Papers published in international conferences
1- Youssef, M.S. and Taha, M. (2007): Some studies on acute
experimental aflatoxicosis in mice. Effect of antioxidants. The 9th Saudi
Gastroentrology Association Conference, May 7-10, 2007, Abha, KSA.
2- Taha, M and M. W Abd- Alazeem (2007): Evaluation of real- time RT-
PCR quantification of HCV compared to other diagnostic methods. The 9 th
Saudi Gastroentrology Association Conference, May 7-10, 2007, Abha, KSA.
3- Taha, M. and O. Galal (2002): Protective effect of melatonin after MPTP
neurotoxicity in mice.Proceeding of the 20th meeting of the European Society
of Veterinary Pathology, Grugliasco (Turin), Italy, 18- 21 September.
4-Taha, M. (2000) : The sensitivity of polymerase chain reaction( RT-PCR)
versus other immunologic methods for the detection of hepatitis C virus in
human sera. Proceeding of the 18th meeting of the European Society of
Veterinary Pathology, Amsterdam, The Netherland, 19-22 September.
5-Taha, M. and Shata,M.T. (1998) : Immunological and pathological studies
on the effect of Praziquantel in DEN- induced hepatic neoplasia in rats.
Proceeding of the IFSTP International Symposium in Cambridge.
C- Papers published in local journals1-Taha, M., R.S. Ibrahim and Asmaa A. A. Hussien (2002 ): Studying The
pathogenicity and RAPD- PCR analysis of different Escherichia coli serotypes
isolated from broilers and layer chickens. Assiut Vet. Med. J., Vol. 46, No. 92:
224- 236.
2- Shata, M.T.; Taha, M. and Seddek, A.Sh. (1993): Immunological and
hematological changes after praziquantel treatment in DEN-induced hepatic
neoplasia in rats. Assiut Vet. Med. J., Vol. 29, No. 57: 162-171.
3-Taha, M. (1992): Modulating effect of praziquantel chemotherapy on early
hepatocarcinogenesis in rats. Egypt. J. Comp. Pathol. Clin. pathol., Vol. 5, No.
2 (Sept): 343-361.
4-Seddek, A.Sh. and Taha, M. (1992): Ultrastructural and serologic changes
associated with hepatic preneoplasia in rats. Proc. 5th Sci. Cong., Fac. Vet.
Med., Assiut Univ., Nov. 8-10, Egypt: 125-134.
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5-Salem, B.; Taha, M. and Abd-El-Motelib, T.Y. (1992): Some studies on
pasteurella anatipestifer infection in gooslings and chicks. Egypt. J. Comp.
Pathol. Clin. Pathol., Vol. 4, No. 2 (Sept.): 313-325.
6-Taha, M. (1992): Pathologic studies on neoplastic mammary affections in
bitches. Egypt. J. Comp. Pathol. Clin. Pthol., Vol. 4, No. 2 (Sept.): 313-325.
7-Taha, M.; Abd-El-Motelib, T.Y.; Salem, B.; El-Ballal, S.S. and El-Zanaty, K.
(1991): Experimental studies on a new listeria monocytogenes isolate in
rabbits. Egypt. J. Comp. Pathol. Clin. Pathol., Vol. 4, No. 2 (Sept.): 301-312.
8-Abdel-Motelib, T.Y.; Taha, M.; Salem, B. and El-Zanaty, K. (1991): First
record of an outbreak of gumboro disease in ducklings in Egypt. Egypt. J.
Comp. Pathol. Clin. Pathol., Vol. 4, No. 2 (Sept.): 327-338.
9-Misk, N.A.; Ahmed, I.H. and Taha, M. (1991): Comparative studies on
different methods of surgical correction of experimentally induced parotid duct
fistula. Assiut Vet. Med. J., Vol. 25, No. 50 (July): 177-185.
10-Shehata, A.; Taha, M.; Ibrahim, Th. and Sedeek, A. (1991):
Toxopathological effects of Ezalo-Mat on male albino mice. Egypt. J. Comp.
Pathol. Clin. Pathol., Vol. 4, No. 1 (March): 187-198.
11-Youssef, M.; Taha, M.; Nagi, A.A. and Bayoumi, A.H. (1990):
Histopathological observations on exocrine pancreas and related neoplasia in
dog. Egypt. J. Comp. Path. Clin. Path., Vol. 3, No. 1, (March): 99-133.
12-Taha, M.; Nagi, A.A.; Youssef, M.S.; Mousa, S. and Bayoumi, A.H. (1990):
Epidemiological and pathological studies on adenovirus infection in broiler
chickens. Assiut Vet. Med. J., Vol. 33, No. 45: 80-89.
13- Nagi, A.A; Youssef, M.S.; Taha, M.; Ahmed, L.S.; Nassef, M.T. and
Bayoumi, A.H. (1990): Lumpy skin disease. I. Cutaneous and testicular
lesions. Assiut Vet. Med. J., Vol. 23, No. 45: 90-99.
14-Nassef, M.T.; Youssef, M.S.; Taha, M.; Ahmed, L.S. and Bayoumi, A.H.
(1990): Studies on coenurosis cerebralis in sheep Assiut Vet. Med. J., Vol. 23,
No. 45: 211-219.
13
15-Youssef, M.S.; Taha, M.; Nagi, A.A. and Bayoumi, A.H. (1990): Use of
liver imprints in diagnosis of some canine diseases. Egypt. J. Comp. Path.
Clin. Path., Vol. 3, No. 1 (March): 89-97.
16-Madaky, F.M.; Seleim, M.A.; Taha, M. and Youssef, M.S. (1990):
Comparison of Polydioxanon and Polyglycolic acid sutures for closure of
arthrotomy incisions in donkeys. Assiut Vet. Med. J., Vol. 23, No. 46: 226-233.
17-Youssef, H.; Mahmoud, A.; Taha, M.; Makady, F. and Seliem, S. (1988):
Effect of duct ligation on the parotid salivary gland of the dog. Assiut Vet.
Med. J., 19(38): 144-147.
18-Taha, M.; Salem, B. and Abdel-Motelib, T.Y. (1986): Some studies on
duck pasteurellosis in the New-Valley. II- Macro-and Micro-morphological
studies. Assiut Vet. Med. J., 17 (34): 119-124.
19-Taha, M. and Youssef, M.S. (1986): Histological and enzyme-
histochemical alterations in the liver induced by total body-irradiation. Assiut
Vet. Med. J., 17 (34): 133-136.
20-Sokar, I.M.; Salem; Abdel-Motelib, T.Y.; Taha, M. and Gerges, S.M.
Susceptibility of different avian species to the newly isolated strain. Assiut Vet.
Med. J., 17 (34): 239-244.
21-Youssef, H.A.; Taha, M.; Aly, A. and Youssef, M.S. (1985): Studies on
uterine healing after caesarotomy in bitches. Assiut Vet. Med. J., Vol. 9 (2): 28-
38.
22-Bayoumi, A.H.; Youssef, M.S.; Taha, M. and Abdel-Raheem, M.H. (1985):
Morphologic and micromorphologic studies on ischaemic limbs in repeatedly
bred mice: 1- Diabetic-like lesions. Assiut Med. J., 9 (2): 39-51.
23-Taha, M.; Bayoumi, A.H.; Mostafa, A.M. and Youssef, H.A. (1985): Histo-
enzymatic alterations of the testis after acute irradiation correlated to its
hormonal function. Assiut Med. J. 9 (3): 558-566.
24-Taha, M. (1985): Report on E. coli infection in Brucella carriers French
Alpine goats at Assiut. Assiut Vet. Med. J., 15 (29): 129-134.
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25-El-Sherry, M.E.; Taha, M. and Gad, N.A. (1984): Immuno-histochemical
studies on experimental coccidiosis in chickens. Assiut Vet. Med. J., 13 (25):
363-385.
Paper published in local conferences1- Nasser Anwar, Mokhtar Taha and Khaled Radad (2009): Thymoquinone
protects dopaminergic neurons against MPP+ and rotenone. Poster submitted
for the 5th Annual Research Day, College of Medicine, King Khalid University,
Abha, KSA, June.
2-Khaled Radad, Mokhtar Taha and Nasser Anwar (2009): Neuroprotective
effect of rotigotine on dopaminergic neurons in primary mesencephalic cell
culture. Submitted for oral presentation for the 5th Annual Research Day,
College of Medicine, King Khalid University, Abha, KSA, June.
3- Taha, M and N. Anwar (2008): Histopathological and biochemical studies
of the chronic hepatotoxic effect of aflatoxin (AFB1) in mice and the role of
antioxidants. The 4th Annual Scientific College of Medicine Research Day,
May 28th, 2008, Abha, KSA.
4-Youssef, H.A.; Taha, M. and Ali, M.A. (1992): Pathologic changes
associated with induced small and large intestinal strangulation obstruction in
donkeys. Proc. 5th Sci. Cong., Fac. Vet. Med., Assiut Univ., Nov. 8-10, Egypt:
167-176.
5-Nagi, A.A. and Taha, M. (1990): Lumpy skin disease: A systemic affection
in new borne calves. The 4th Scientific Congress, Fac. Vet. Med., Assiut
Univ., Proceeding, Vol. IV: 960-972.
6-Taha, M. and Laila, S.A. (1990): Clinico-Pathologic studies on some field
problems of reared calves. The 4th Scientific Congress, Fac. Vet. Med., Assiut
Univ., Proceeding Vol. IV: 946-959.
7-Bolbol, A.E.; Taha, M.; Laila, S.A. and Bayoumi, A.H. (1990): Angiopathic
alterations of the cranial mesenteric artery in equine strongyloidosis. The 4 th
Scientific Congress, Fac. Vet. Med., Assiut Univ., Proceeding Vol. II: 282-290.
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