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Book Chapters
Lifeng Kang, Han Hui Cheong, Sui Yung Chan, Perry Fung Chye Lim: Applications of Small‐Molecule Gels ‐ Drug
Delivery. Soft Fibrillar Materials, 08/2013: pages 115‐128; ISBN: 9783527331628
Lifeng Kang, Vaddi Haranath Kumar, Perry Fung Chye Lim, Han Hui Cheong, Sui Yung Chan: Natural Products. Natural
Products, 01/2013: pages 3757‐3774; ISBN: 978‐3‐642‐22143‐9
Journal Publications
Ong, KY, E Yap, YMF Chia, HY Tay, P Ting, SY Chan, YH Kwan: Impact of community‐based cardiac rehabilitation on
clinical parameters of patients with cardiovascular diseases. ASEAN Heart Journal, 24, no.1 (2016): 91–7. DOI
10.7603/s40602‐016‐0005‐4.
Teo, CHD, PSL Ng, SH Tan, AT Lim, DSL Toh, SY Chan and HH Cheong*: Drug‐induced liver injury associated with
Complementary and Alternative Medicine: A review of adverse event reports in an Asian Community from
2009 to 2014. BMC Complementary and Alternative Medicine, 16, no. 192 (2016): DOI 10.1186/s12906‐016‐
1168‐z.
Chen, CL, YJ Chong, SL Hie, R Sultana, SHD Lee, WSD Chan, SY Chan and HH Cheong*: Complementary and
Alternative Medicines use among pediatric epilepsy patients in a multi ethnic community. Epilepsy &
Behavior, 60 (2016): 68‐74. (United States).
Saigal, A, WK Ng, RBH Tan and SY Chan*: Controlled release inhalable polymeric microspheres for treatment of
pulmonary arterial hypertension. Current Pharmaceutical Design, 21, no. 40 (2015): 5868‐76. (Netherlands).
Shi‐Peng Sun, Sui Yung Chan, Weihong Xing, Yong Wang, Tai‐Shung Chung: Facile synthesis of dual‐layer organic
solvent nanofiltration (OSN) hollow fiber membranes. ACS Sustainable Chemistry & Engineering 11/2015;
3(12): 3019‐23. DOI:10.1021/acssuschemeng.5b01292.
Ariana Low, Si Ling Kok, Yuet Mei Khong, Sui Yung Chan, Rajeev Gokhale: A new test unit for disintegration end‐point
determination of orodispersible films. Journal of Pharmaceutical Sciences 08/2015; 104(11).
DOI:10.1002/jps.24609
Melanie Yee Lee Siaw, Daniel Ek Kwang Chew, Matthias Paul Han Sim Toh, Darren Ee‐Jin Seah, Ruimin Chua, Jielin
Tan, Evonne Yanqun Lee, Sui Yung Chan, Joyce Yu‐Chia Lee: Metabolic parameters in type 2 diabetic patients
with varying degrees of glycemic control during ramadan: An observational study. Epilepsy & Behavior
05/2015; 7(1). DOI:10.1111/jdi.12374.
Shi Peng Sun, Sui Yung Chan, Tai‐Shung Chung: A slow‐fast phase separation (SFPS) process to fabricate dual‐layer
hollow fiber substrates for thin‐film composite (TFC) organic solvent nanofiltration (OSN) membranes. Chemical
Engineering Science 03/2015; 129. DOI:10.1016/j.ces.2015.02.043.
Anahita Fathi‐Azarbayjani, Kai Xin Ng, Yew Weng Chan, Sui Yung Chan: Lipid vesicles for the skin delivery of
diclofenac: Cerosomes vs. other lipid suspensions. Advanced Pharmaceutical Bulletin 03/2015; 5(1):25‐33.
DOI:10.5681/apb.2015.004.
Melanie Yee Lee Siaw, Daniel EK Kwang Chew, Rinkoo Dalan, Shaikh Abdul Kader Kamaldeen Abdul Shakoor, Noorani
Othman, Chor Hui Choo, Nur Hidayah Shamsuri, Siti Nurhana Abdul Karim, Sui Yung Chan, Joyce Yu‐Chia Lee:
Evaluating the effect of ramadan fasting on muslim patients with diabetes in relation to use of medication and
lifestyle patterns: A prospective study. International Journal of Endocrinology 11/2014; 2014.
DOI:10.1155/2014/308546.
Zhiwei Thong, Gang Han, Yue Cui, Jie Gao, Tai‐Shung Chung, Sui Yung Chan, Shawn Wei: Novel nanofiltration
membranes consisting of a sulfonated pentablock copolymer rejection layer for heavy metal removal.
Environmental Science and Technology 11/2014; 48(23). DOI:10.1021/es5031239.
A. Saigal, S. T. Heng, W. K. Ng, R. B. H. Tan, S. Y. Chan: Preparation and characterization of controlled release
microspheres for management of pulmonary hypertension. Respirology 11/2014; 19:15.
Shi‐Peng Sun, Kang‐Jia Lu, Sui‐Yung Chan, Tai‐Shung Chung: Enhancement of flux and solvent stability of Matrimid (R)
thin‐film composite membranes for organic solvent Nanofiltration. AIChE Journal 10/2014; 60(10).
DOI:10.1002/aic.14558.
Chan, SY and KZ Yap*, "Role of antipsychotics for treating behavioral and psychological symptoms of dementia".
World Journal of Pharmacology, 2014, 4(3): 174‐185. (United States).
Yufei Chen, Ee Heok Kua, Sui Yung Chan, Joyce Lee, Kai Zhen Yap: The impact of psychotropic use monitoring (PUM)
on inappropriate prescribing of antipsychotics in a nursing home. Pharmacotherapy 06/2014; 34(6):e82‐3.
Kai Zhen Yap, Sui Yung Chan, Joyce Lee: "PLEAD" for laxatives ‐ Development and implementation of the pharmacist‐
led education on appropriate drug‐use program in nursing homes. Pharmacotherapy 05/2014; 34(6):e83.
Kai Zhen Yap, Ee Heok Kua, Sui Yung Chan, Joyce Yu‐Chia Lee: Improving the appropriateness of antipsychotic
prescribing for behavioral and psychological symptoms of dementia (BPSD): A pilot study of the psychotropic
use monitoring (PUM) program. Open Journal of Psychiatry 04/2014; 4(2):153‐62.
DOI:10.4236/ojpsych.2014.42020
Ding Yu Xing, Sui Yung Chan, Tai‐Shung Chung: The ionic liquid [EMIM]OAc as a solvent to fabricate stable
polybenzimidazole membranes for organic solvent nanofiltration. Green Chemistry 02/2014; 16(3).
DOI:10.1039/C3GC41634H.
Anahita Fathi‐Azarbayjani, Poh Leng Tan, Yew Ying Chan, Sui Yung Chan: Ascorbic acid for the safe use of a sunscreen
agent: Accumulation of nano zinc oxide and titanium dioxide on the skin. Scientia Pharmaceutica 12/2013;
81(4):1141‐1150. DOI:10.3797/scipharm.1306‐05.
Jing Pan, Sui Yung Chan, John E A Common, Shahrouz Amini, Ali Miserez, E. Birgitte Lane, Lifeng Kang: Fabrication of
a 3D hair follicle‐like hydrogel by soft lithography. Journal of Biomedical Materials Research Part A 11/2013;
101(11). DOI:10.1002/jbm.a.34628.
J.S. Kochhar, S.Y. Chan, P.S. Ong, W.G. Lee, L. Kang: Microfluidic devices for drug discovery and analysis. Drug Discov
Today. 2008 Jan; 13(1‐2): 1–13. DOI:10.1016/j.drudis.2007.10.003.
Ariana Qiao Jun Low, Johannes Parmentier, Yuet Mei Khong, Cherry Chang Er Chai, Thin Yu Tun, Jacqueline E Berania,
Xueming Liu, Rajeev Gokhale, Sui Yung Chan: Effect of type and ratio of solubilising polymer on characteristics
of hot‐melt extruded orodispersible films. International Journal of Pharmaceutics 07/2013; 455(1‐2).
DOI:10.1016/j.ijpharm.2013.07.046
Aparna Saigal, Wai Kiong Ng, Reginald B.H. Tan, Sui Yung Chan: Controlled release inhalable polymeric microspheres
for treatment of pulmonary arterial hypertension. International Journal of Pharmaceutics 04/2013; 450(1).
DOI:10.1016/j.ijpharm.2013.04.011.
Joshua Levi Jacobs, Dujeepa D Samarasekera, Wai Keung Chui, Sui Yung Chan, Li Lian Wong, Sok Ying Liaw, Mui Ling
Tan, Sally Chan: Building a successful platform for interprofessional education for health professions in an Asian
university. Medical Teacher 03/2013; 35(5). DOI:10.3109/0142159X.2013.775414.
Ding Yu Xing, Sui Yung Chan, Tai‐Shung Chung: Fabrication of porous and interconnected PBI/P84 ultrafiltration
membranes using [EMIM]OAc as the green solvent. Chemical Engineering Science 01/2013; 87:194–203.
DOI:10.1016/j.ces.2012.10.004.
Han Hui Cheong, Jeyakumar Masilamani, Chun Yong Eric Chan, Sui Yung Chan, Toan Thang Phan: Metabolically
functional hepatocyte‐like cells from human umbilical cord lining epithelial cells. Assay and Drug Development
Technologies 10/2012; 11(2). DOI:10.1089/adt.2011.444.
Jaspreet Singh Kochhar, Sui Yung Chan, Pei Shi Ong, Lifeng Kang: Clinical therapeutics for phenylketonuria. Drug
Delivery and Translational Research 08/2012; 2(4). DOI:10.1007/s13346‐012‐0067‐1.
Jaspreet Singh Kochhar, Shui Zou, Sui Yung Chan, Lifeng Kang: Protein encapsulation in polymeric microneedles by
photolithography. International Journal of Nanomedicine 06/2012; 7:3143‐54. DOI:10.2147/IJN.S32000.
Shi Peng Sun, T. Alan Hatton, Sui Yung Chan, Tai‐Shung Chung: Novel thin‐film composite nanofiltration hollow fiber
membranes with double repulsion for effective removal of emerging organic matters from water. Journal of
Membrane Science 05/2012; s 401–402:152–162. DOI:10.1016/j.memsci.2012.01.046.
Ding Yu Xing, Sui Yung Chan, Tai‐Shung Chung: Molecular interactions between polybenzimidazole and [EMIM]OAc,
and derived ultrafiltration membranes for protein separation. Green Chemistry 05/2012; 14(5):1405‐12.
DOI:10.1039/C2GC35134J.
Jaspreet Singh Kochhar, Wei Jiang Goh, Sui Yung Chan, Lifeng Kang: A simple method of microneedle array
fabrication for transdermal drug delivery. Drug Development and Industrial Pharmacy 04/2012; 39(2).
DOI:10.3109/03639045.2012.679361.
Pei‐Shi Ong, Xin‐Qiao Wang, Hai‐Shu Lin, Sui‐Yung Chan, Paul C Ho: Synergistic effects of suberoylanilide hydroxamic
acid combined with cisplatin causing cell cycle arrest independent apoptosis in platinum‐resistant ovarian
cancer cells. International Journal of Oncology 02/2012; 40(5):1705‐13. DOI:10.3892/ijo.2012.1354.
Pei‐Shi Ong, Sui‐Yung Chan, Paul C Ho: Microarray analysis revealed dysregulation of multiple genes associated with
chemoresistance to As2O3 and increased tumor aggressiveness in a newly established arsenic‐resistant ovarian
cancer cell line, OVCAR‐3/AsR. European Journal of Pharmaceutical Sciences 12/2011; 45(3):367‐78.
DOI:10.1016/j.ejps.2011.12.003.
Ling‐Zhi Wang, Rina Yue‐Ling Ong, Tan‐Min Chin, Win‐Lwin Thuya, Seow‐Ching Wan, Andrea Li‐Ann Wong, Sui‐Yung
Chan, Paul C Ho, Boon‐Cher Goh: Method development and validation for rapid quantification of
hydroxychloroquine in human blood using liquid chromatography‐tandem mass spectrometry. Journal of
Pharmaceutical and Biomedical Analysis 12/2011; 61:86‐92. DOI:10.1016/j.jpba.2011.11.034.
Jing Pan, Sui Yung Chan, Won Gu Lee, Lifeng Kang: Microfabricated particulate drug‐delivery system. Biotechnology
Journal 12/2011; 6(12):1477‐87. DOI:10.1002/biot.201100237.
Anahita Fathi Azarbayjani, Jia Vu Khu, Yew Weng Chan, Sui Yung Chan: Development and characterization of skin
permeation retardants and enhancers: A comparative study of levothyroxine‐loaded PNIPAM, PLA, PLGA and
EC microparticles. Biopharmaceutics & Drug Disposition 10/2011; 32(7):380‐8. DOI:10.1002/bdd.766.
Ling‐Zhi Wang, Michelle Yi‐Xiu Lim, Tan‐Min Chin, Win‐Lwin Thuya, Pei‐Ling Nye, Andrea Wong, Sui‐Yung Chan,
Boon‐Cher Goh, Paul C Ho: Rapid determination of gefitinib and its main metabolite, O‐desmethyl gefitinib in
human plasma using liquid chromatography‐tandem mass spectrometry. Journal of Chromatography. B,
Analytical Technologies in the Biomedical and Life Sciences 06/2011; 879(22):2155‐61.
DOI:10.1016/j.jchromb.2011.05.056.
Manish K. Chourasia, Lifeng Kang, Sui Yung Chan: Nanosized ethosomes bearing ketoprofen for improved
transdermal delivery. Results in Pharma Sciences 05/2011; 1(1):60–7. DOI:10.1016/j.rinphs.2011.10.002.
Hairui Li, Jaspreet Singh Kochhar, Jing Pan, Sui Yung Chan, Lifeng Kang: Nano/microscale technologies for drug
delivery. Journal of Mechanics in Medicine and Biology 04/2011; 21(11):337‐67.
DOI:10.1142/S021951941100406X.
Pei‐Shi Ong, Sui‐Yung Chan, Paul C Ho: Differential augmentative effects of buthionine sulfoximine and ascorbic acid
in As2O3‐induced ovarian cancer cell death: Oxidative stress‐independent and ‐dependent cytotoxic
potentiation. International Journal of Oncology 03/2011; 38(6):1731‐9. DOI:10.3892/ijo.2011.986.
A Mukhopadhyay, D.V. Do, C.T. Ong, Y.T. Khoo, J Masilamani, S.Y. Chan, A.S. Vincent, P.K. Wong, C.P. Lim, X Cao, I.J.
Lim, T.T. Phan: The role of stem cell factor and c‐KIT in keloid pathogenesis: Do tyrosine kinase inhibitors have a
potential therapeutic role? British Journal of Dermatology 02/2011; 164(2):372‐86. DOI:10.1111/j.1365‐
2133.2010.10035.x.
H H Cheong, J Masilamani, T T Phan, S Y Chan: Cord lining progenitor cells: Potential in vitro adipogenesis model.
International Journal of Obesity (2005) 11/2010; 34(11):1625‐33. DOI:10.1038/ijo.2010.86.
Y. Y. Cai BSc, Z. Wang BEng, Z. G. Ge PhD MBBS, Y. Y. Cai, C. W. Yap, Z. Wang, P. C. Ho, S. Y. Chan, K. Y. Ng, Z. G. Ge, H.
S. Lin: Solubilization of vorinostat by cyclodextrins. Journal of Clinical Pharmacy and Therapeutics 09/2010;
35(5):521‐6. DOI:10.1111/j.1365‐2710.2009.01095.x.
Anahita Fathi‐Azarbayjani, Lin Qun, Yew Weng Chan, Sui Yung Chan: Novel vitamin and gold‐loaded nanofiber facial
mask for topical delivery. AAPS PharmSciTech 09/2010; 11(3):1164‐70. DOI:10.1208/s12249‐010‐9475‐z.
Anahita Fathi Azarbayjani, Haishu Lin, Chun Wei Yap, Yew Weng Chan, Sui Yung Chan: Surface tension and wettability
in transdermal delivery: A study on the in‐vitro permeation of haloperidol with cyclodextrin across human
epidermis. J Pharm Pharmacol. 06/2010; 62(6):770‐8. DOI:10.1211/jpp.62.06.0014.
Anandaroop Mukhopadhyay, Man Yi Wong, Sui Y Chan, Dang V Do, Audrey Khoo, Chee T Ong, Han H Cheong, Ivor J
Lim, Thang T Phan: Syndecan‐2 and decorin: Proteoglycans with a difference ‐ Implications in keloid
pathogenesis. The Journal of Trauma 04/2010; 68(4):999‐1008. DOI:10.1097/TA.0b013e3181c4070d.
Prashant N. Balani, S.Y. Wong, W.K. Ng, E Widjaja, R.B.H. Tan, S.Y. Chan: Influence of polymer content on stabilizing
milled amorphous salbutamol sulphate. International Journal of Pharmaceutics 03/2010; 391(1‐2):125‐36.
DOI:10.1016/j.ijpharm.2010.02.029.
Anahita Fathi‐Azarbayjani, Sui Yung Chan: Single and multi‐layered nanofibers for rapid and controlled drug delivery.
Chemical & Pharmaceutical Bulletin 02/2010; 58(2):143‐6. DOI:10.1248/cpb.58.143.
Anahita Fathi Azarbayjani, Jayarama Reddy Venugopal, Seeram Ramakrishna, Perry Fung Chye Lim, Yew Weng Chan,
Sui Yung Chan: Smart polymeric nanofibers for topical delivery of levothyroxine. Journal of Pharmacy and
Pharmaceutical Sciences 01/2010; 13(3):400‐10.
Perry Fung Chye Lim, Xiang Yang Liu, Sui Yung Chan: A review on terpenes as skin penetration enhancers in
transdermal drug delivery. Journal of Essential Oil Research 09/2009; 21(5‐5):423‐8.
DOI:10.1080/10412905.2009.9700208.
Yi‐Jing Lim, Sui‐Yung Chan, Yu Ko: Stigma and health‐related quality of life in Asian adults with epilepsy. Epilepsy
Research 09/2009; 87(2‐3):107‐19. DOI:10.1016/j.eplepsyres.2009.08.014.
Anahita Fathi Azarbayjani, En Hui Tan, Yew Weng Chan, Sui Yung Chan: Transdermal delivery of haloperidol by
proniosomal formulations with non‐ionic surfactants. Biological & Pharmaceutical Bulletin 08/2009;
32(8):1453‐8.
Ching Ye Hong, Lai Wah Chan, Lean Huat Lim, Sui Yung Chan: Case studies in community pharmacy: The contribution
of family physicians to the teaching of community pharmacy. Medical Teacher 07/2009; 20(5):476‐479.
DOI:10.1080/01421599880625.
Kevin Yi‐Lwern Yap, Tommy Kok Heng Lai, Sui Yung Chan, Chu Sing Lim: Infrared authentication of ginseng species:
The use of the 2‐6PC rule. Journal of AOAC International 03/2009; 92(2):672‐9.
Yi Li, Sim Chuan Soh, Tai‐Shung Chung, Sui Yung Chan: Exploration of ionic modification in dual‐layer hollow fiber
membranes for long‐term high‐performance protein separation. AIChE Journal 02/2009; 55(2):321‐30.
DOI:10.1002/aic.11671.
Anahita Fathi Azarbayjani, Abolghasem Jouyban, Sui Yung Chan: Impact of surface tension in pharmaceutical
sciences. Journal of Pharmacy and Pharmaceutical Sciences 02/2009; 12(2):218‐28.
Anahita Fathi Azarbayjani, En Hui Tan, Yew Weng Chan, Sui Yung Chan: Transdermal delivery of haloperidol by
proniosomal formulations with nonionic surfactants. Biological & Pharmaceutical Bulletin 01/2009; 32(8):1453‐
8. DOI:10.1248/bpb.32.1453.
Prashant N Balani, Wai Kiong Ng, Reginald B.H. Tan, Sui Yung Chan: Influence of excipients in comilling on mitigating
milling‐induced amorphization or structural disorder of crystalline pharmaceutical actives. Journal of
Pharmaceutical Sciences 01/2009; 99(5):2462‐74. DOI:10.1002/jps.21998.
Haishu Lin, Qiuyi Choo, Jia Yang, Yoshiya Tanaka, Sui Yung Chan, Paul Ho: Anti‐proliferative and anti‐inflammatory
activities of belinostat: Therapeutic potential for rheumatoid arthritis? Bone 10/2008; 43.
DOI:10.1016/j.bone.2008.07.199.
Perry Fung Chye Lim, Xiang Yang Liu, Lifeng Kang, Paul Chi Lui Ho, Sui Yung Chan: Physicochemical effects of terpenes
on organogel for transdermal drug delivery. International Journal of Pharmaceutics 07/2008; 358(1‐2):102‐7.
DOI:10.1016/j.ijpharm.2008.02.021.
Xin Liu, Sui Yung Chan, Paul Chi‐Lui Ho: Liu X, Chan SY, Ho PC: Comparison of the in vitro and in vivo effects of
retinoids either alone or in combination with cisplatin and 5‐fluorouracil on tumor development and metastasis
of melanoma. Cancer Chemotherapy and Pharmacology 06/2008; 63(1):167‐74. DOI:10.1007/s00280‐008‐
0763‐1.
Ashlynn L Z Lee, Yong Wang, Wen‐Hui Ye, Ho Sup Yoon, Sui Yung Chan, Yi‐Yan Yang: Efficient intracellular delivery of
functional proteins using cationic polymer core/shell nanoparticles. Biomaterials 04/2008; 29(9):1224‐32.
DOI:10.1016/j.biomaterials.2007.11.021.
Yi Li, Tai‐Shung Chung, Sui Yung Chan: High‐affinity sulfonated materials with transition metal counterions for
enhanced protein separation in dual‐layer hollow fiber membrane chromatography. Journal of
Chromatography A 04/2008; 1187(1‐2):285‐8. DOI:10.1016/j.chroma.2008.02.047.
Kevin Yi‐Lwern Yap, Sui Yung Chan, Chu Sing Lim: The reliability of traditional authentication – A case of ginseng
misfit. Food Chemistry 03/2008; 107(1‐107):570‐5. DOI:10.1016/j.foodchem.2007.07.055.
A Mukhopadhyay, A Khoo, HH Cheong, SY Chan, O Aalami, IJ Lim, TT Phan: Targeting of Sp1 transcription factor: A
novel therapeutic approach for keloids, an in vitro analysis. Experimental Dermatology 01/2008; 16(12):1023‐
31. DOI:10.1111/j.1600‐0625.2007.00627.x.
L Kang, A.L. Poh, S K Fan, P C Ho, Y.W. Chan, S.Y. Chan: Reversible effects of permeation enhancers on human skin.
European Journal of Pharmaceutics and Biopharmaceutics 09/2007; 67(1):149‐55.
DOI:10.1016/j.ejpb.2006.12.010.
Hai‐Shu Lin, Wendy Wen Yi Leong, Jie An Yang, Pei Lee, Sui Yung Chan, Paul C Ho: Biopharmaceutics of 13‐cis‐retinoic
acid (isotretinoin) formulated with modified β‐cyclodextrins. International Journal of Pharmaceutics 09/2007;
341(1‐2):238‐45. DOI:10.1016/j.ijpharm.2007.03.050.
L Kang, CW Yap, PFC. Lim, YZ Chen, PC Ho, YW Chan, GP Wong, SY Chan: Formulation development of transdermal
dosage forms: quantitative structure‐activity relationship model for predicting activities of terpenes that
enhance drug penetration through human skin. Journal of Controlled Release 08/2007; 120(3):211‐9.
DOI:10.1016/j.jconrel.2007.05.006.
Kevin Yi‐Lwern Yap, Sui Yung Chan, Chu Sing Lim: Infrared‐based protocol for the identification and categorization of
ginseng and its products. Food Research International 06/2007; 40(5):643‐52.
DOI:10.1016/j.foodres.2006.11.009.
Anandaroop Mukhopadhyay, Sui Yung Chan, Ivor J Lim, David J Phillips, Thang T Phan: The role of the activin system
in keloid pathogenesis. AJP Cell Physiology 05/2007; 292(4):C1331‐8. DOI:10.1152/ajpcell.00373.2006.
Kevin Yi‐Lwern Yap, Sui Yung Chan, Chu Sing Lim: Authentication of traditional Chinese medicine using infrared
spectroscopy: Distinguishing between ginseng and its morphological fakes. Journal of Biomedical Science
04/2007; 14(2):265‐73. DOI:10.1007/s11373‐006‐9133‐3.
Perry Fung Chye Lim, Xiang Yang Liu, Lifeng Kang, Paul Chi Lui Ho, Yew Weng Chan, Sui Yung Chan: Limonene GP1/PG
organogel as a vehicle in transdermal delivery of haloperidol. International Journal of Pharmaceutics 04/2006;
311(1‐2):157‐64. DOI:10.1016/j.ijpharm.2005.12.042.
Wai Johnn Sam, Lai San Tham, Michael J Holmes, Marion Aw, Seng Hock Quak, Kang Hoe Lee, Seng Gee Lim, Krishnan
Prabhakaran, Sui Yung Chan, Paul C Ho: Population Pharmacokinetics of Tacrolimus in Whole Blood and Plasma
in Asian Liver Transplant Patients. Clinical Pharmacokinetics 02/2006; 45(1):59‐75. DOI:10.2165/00003088‐
200645010‐00004.
Lifeng Kang, Paul C. Ho, SY Chan: Interactions between a skin penetration enhancer and the main components of
human stratum corneum lipids isothermal titration calorimetry study. Journal of Thermal Analysis and
Calorimetry 01/2006; 83(1):27‐30. DOI:10.1007/s10973‐005‐7050‐8.
Kevin Yi‐Lwern Yap, Sui Yung Chan, Yew Weng Chan, Chu Sing Lim: Overview on the analytical tools for quality
control of natural product‐based supplements: A case study of ginseng. Assay and Drug Development
Technologies 01/2006; 3(6):683‐99. DOI:10.1089/adt.2005.3.683.
Lifeng Kang, X.Y. Liu, P.D. Sawant, P.C. Ho, YW Chan, SY Chan: SMGA gels for the skin permeation of haloperidol.
Journal of Controlled Release 09/2005; 106(1‐2):88‐98. DOI:10.1016/j.jconrel.2005.04.017.
A Mukhopadhyay, E.K.J. Tan, Y.T.A. Khoo, S.Y. Chan, I.J. Lim, T.T. Phan: Mukhopadhyay A, Tan EK, Khoo YT et al.
Conditioned medium from keloid keratinocyte/keloid fibroblast coculture induces contraction of fibroblast‐
populated collagen lattices. British Journal of Dermatology 05/2005; 152(4):639‐45. DOI:10.1111/j.1365‐
2133.2005.06545.x.
Toan‐Thang Phan, IJ Lim, SY Chan, EK Tan, ST Lee, MT Longaker: Suppression of transforming growth factor
Beta/Smad signaling in kelold‐derived fibroblasts by quercelin: Implications for the treatment of excessive
scars. Journal of Trauma 11/2004; 57(5):1032‐1037. DOI:10.1097/01.TA.0000114097.46566.EB.
Xin Liu, Hai‐Shu Lin, Sui Yung Chan, Paul C Ho: Biopharmaceutics of β‐cyclodextrin derivative‐based formulations of
acitretin in Sprague‐Dawley rats. Journal of Pharmaceutical Sciences 04/2004; 93(4):805‐15.
DOI:10.1002/jps.10578.
Toan‐Thang Phan, IJ Lim, L Sun, SY Chan, BH Bay, EK Tan, ST Lee: Quercetin inhibits fibronectin production by keloid‐
derived fibroblasts. Implication for the treatment of excessive scars. Journal of Dermatological Science
01/2004; 33(3):192‐4. DOI:10.1016/j.jdermsci.2003.08.008.
Xin Liu, Hai‐Shu Lin, JC Thenmozhiyal, Sui Yung Chan, Paul C Ho: Inclusion of acitretin into cyclodextrins: Phase
solubility, photostability, and physicochemical characterization. Journal of Pharmaceutical Sciences 12/2003;
92(12):2449‐57. DOI:10.1002/jps.10495.
Toan‐Thang Phan, Li Sun, Boon‐Huat Bay, Sui‐Yung Chan, Seng‐Teik Lee: Dietary compounds inhibit proliferation and
contraction of keloid and hypertrophic scar‐derived fibroblasts in vitro. The Journal of Trauma 07/2003;
54(6):1212‐24. DOI:10.1097/01.TA.0000030630.72836.32.
Toan‐Thang Phan, P See, E Tran, TTT Nguyen, SY Chan, ST Lee, H Huynh: Suppression of insulin‐like growth factor
signalling pathway and collagen expression in keloid‐derived fibroblasts by quercetin: Its therapeutic potential
use in the treatment and/or prevention of keloids. British Journal of Dermatology 04/2003; 148(3):544‐52.
DOI:10.1046/j.1365‐2133.2003.05174.x.
Haranath Kumar Vaddi, Paul Chi‐Lui Ho, Yew Weng Chan, Sui Yung Chan: Oxide Terpenes as human skin penetration
enhancers of haloperidol from ethanol and propylene glycol and their modes of action on stratum corneum.
Biological & Pharmaceutical Bulletin 03/2003; 26(2):220‐8. DOI:10.1248/bpb.26.220.
LZ Wang, PC Ho, HS Lee, HK Vaddi, YW Chan, Chan Sui Yung: Quantitation of paclitaxel in micro‐sample rat plasma by
a sensitive reversed‐phase HPLC assay. Journal of Pharmaceutical and Biomedical Analysis 03/2003; 31(2):283‐
9. DOI:10.1016/S0731‐7085(02)00611‐8.
Jita Liu, Sui Y Chan, Paul C Ho: Polymer‐coated microparticles for the sustained release of nitrofurantoin. Journal of
Pharmacy and Pharmacology 10/2002; 54(9):1205‐12. DOI:10.1211/002235702320402044.
HK Vaddi, PC Ho, SY Chan: Terpenes in propylene glycol as skin‐penetration enhancers: permeation and partition of
haloperidol, Fourier transform infrared spectroscopy and differential scanning calorimetry. Journal of
Pharmaceutical Sciences 07/2002; 91(7):1639‐51. DOI:10.1002/jps.10160.
HK Vaddi, PC Ho, YW Chan, SY Chan: Terpenes in ethanol: Haloperidol permeation and partition through human skin
and stratum corneum changes. Journal of Controlled Release 06/2002; 81(1‐2):121‐33. DOI:10.1016/S0168‐
3659(02)00057‐3
Yong Chen, Sui Y Chan, Paul C Ho: Isobolographic analysis of the analgesic interactions between ketamine and
tramadol. Journal of Pharmacy and Pharmacology 06/2002; 54(5):623‐31. DOI:10.1211/0022357021778934.
T. Thang Phan, Lingzhi Wang, Patrick See, Renee Jacqueline Grayer, SY Chan, Seng Teik Lee: Phenolic compounds of
Chromolaena odorata protect cultured skin cells from oxidative damage: Implication for cutaneous wound
healing. Biological & Pharmaceutical Bulletin 01/2002; 24(12):1373‐9. DOI:10.1248/bpb.24.1373.
H‐S Lin, AB Barua, JA Olson, KSY Low, SY Chan, ML Shoon, PC Ho: Pharmacokinetic study of all‐trans‐retinoyl‐ ‐D‐
glucuronide in Sprague‐Dawley rats after single and multiple intravenous administration(s). Journal of
Pharmaceutical Sciences 12/2001; 90(12):2023‐31. DOI:10.1002/jps.1153.
TT Phan, Patrick See, ST Lee, SY Chan: Protective effects of curcumin against oxidative damage on skin cells in vitro:
its implication for wound healing. The Journal of Trauma 12/2001; 51(5):927‐31. DOI:10.1097/00005373‐
200111000‐00017.
Haranath Kumar Vaddi, Ling Zhi Wang, Paul Chi‐Lui Ho, Yew Weng Chan, Sui Yung Chan: Effect of cetrimide and
ascorbic acid on in vitro human skin permeation of haloperidol. Chemical & Pharmaceutical Bulletin 12/2001;
49(11):1395‐400. DOI:10.1248/cpb.49.1395.
Phan Toan Thang, See Patrick, Lee Seng Teik, Chan Sui Yung: Anti‐oxidant effects of the extracts from the leaves of
Chromolaena odorata on human dermal fibroblasts and epidermal keratinocytes against hydrogen peroxide
and hypoxanthine‐xanthine oxidase induced damage. Burns 07/2001; 27(4):319‐27. DOI:10.1016/S0305‐
4179(00)00137‐6.
H K Vaddi, L Z Wang, P C Ho, SY Chan: Vaddi HK, Wang LZ, Ho PC, Chan SY: Effect of some enhancers on the
permeation of haloperidol through rat skin in vitro. International Journal of Pharmaceutics 02/2001;
212(2):247‐55. DOI:10.1016/S0378‐5173(00)00616‐5.
W. J. Sam, M. Aw, S. H. Quak, S. M. Lim, B. G. Charles, SY Chan, P. C. Ho: Population pharmacokinetics of tacrolimus
in Asian paediatric liver transplant patients. British Journal of Clinical Pharmacology 11/2000; 50(6):531‐41.
DOI:10.1046/j.1365‐2125.2000.00288.x.
H S Lin, C S Chean, Y Y Ng, S Y Chan, P C Ho: 2‐Hydroxypropyl‐β‐cyclodextrin increases aqueous solubility and
photostability of all‐trans‐retinoic acid. Journal of Clinical Pharmacy and Therapeutics 09/2000; 25(4):265‐9.
DOI:10.1046/j.1365‐2710.2000.00285.x.
SC Li, SY Chan, PPC How: PWP6: A preliminary study of provision of pharmaceutical care in community
pharmaceutical care in community pharmacy in Singapore: Cost analysis & patient willingness to pay. Value in
Health 03/2000; 3(2):116‐7. DOI:10.1016/S1098‐3015(11)70492‐2.
Hai‐Shu Lin, Sui Yung Chan, Kerwin Siew Yang Low, Mei Leng Shoon, Paul C. Ho: Kinetic study of a 2‐hydroxypropyl‐?‐
cyclodextrin‐based formulation of all‐trans‐retinoic acid in Sprague‐Dawley rats after oral or intravenous
administration. Journal of Pharmaceutical Sciences 02/2000; 89(2):260‐7. DOI:10.1002/(SICI)1520‐
6017(200002)89:2<260::AID‐JPS13>3.0.CO;2‐Q.
Toan‐Thang Phan, S T Lee, S Y Chan, M A Hughes, G W Cherry: Investigating plant‐based medicines for wound healing
with the use of cell culture technologies and in vitro models: A review. Annals of the Academy of Medicine,
Singapore 02/2000; 29(1):27‐36.
J Liu, SY Chan, P C Ho: Effects of sucrose, citric buffer and glucose oxidase on the stability of captopril in liquid
formulations. Journal of Clinical Pharmacy and Therapeutics 05/1999; 24(2):145‐50. DOI:10.1046/j.1365‐
2710.1999.00213.x.
T H How, WY Loo, K L Yow, LY Lim, E W Chan, P C Ho, SY Chan: Stability of cefazolin sodium eye drops. Journal of
Clinical Pharmacy and Therapeutics 03/1998; 23(1):41‐7. DOI:10.1046/j.1365‐2710.1998.00136.x.
M.Y.F. Lye, K L Yow, L Y Lim, S Y Chan, E Chan, P C Ho: Effects of ingredients on stability of captopril in
extemporaneously prepared oral liquids. American Journal of Health‐System Pharmacy 12/1997; 54(21):2483‐
7.
M. M. S. Hor, SY Chan, K. L. Yow, LY Lim, E. Chan, P. C. Ho: Stability of admixtures of pethidine and metoclopramide in
aqueous solution, 5% dextrose and 0.9% sodium chloride. Journal of Clinical Pharmacy and Therapeutics
11/1997; 22(5):339‐45. DOI:10.1111/j.1365‐2710.1997.tb00016.x.
M. M. S Hor, S Y Chan, K L Yow, L Y Lim, E Chan, P C Ho: Stability of morphine sulphate in saline under simulated
patient administration conditions. Journal of Clinical Pharmacy and Therapeutics 11/1997; 22(5‐6):405‐10.
DOI:10.1046/j.1365‐2710.1997.00121.x.
L Y Lim, L L Tan, E.W.Y. Chan, K L Yow, S Y Chan, P.C.L. Ho: Stability of phenoxybenzamine hydrochloride in various
vehicles. American Journal of Health‐System Pharmacy 09/1997; 54(18):2073‐8.
S.Y. Chan, A Li Wan Po: Quantitative evaluation of drug‐induced erythema by using a tristimulus colour analyzer:
experimental design and data analysis. Skin Pharmacology 02/1993; 6(4):298‐312. DOI:10.1159/000211153.
Sui Yung Chan, Alain Li Wan Po: Quantitative skin blanching assay of corticosteroid creams using tristimulus colour
analysis. Journal of Pharmacy and Pharmacology 06/1992; 44(5):371‐8. DOI:10.1111/j.2042‐
7158.1992.tb03628.x.
S.Y. Chan, A. Li Wan Po: Prodrugs for dermal delivery. International Journal of Pharmaceutics 10/1989; 55(1‐55):1‐16.
DOI:10.1016/0378‐5173(89)90270‐6.
Sui Yung Chan, Alain Li Wan Po: Quantitative assessment of non‐steroidal anti‐inflammatory topical products in
nicotinate‐induced erythema. International Journal of Pharmaceutics 06/1982; 83(s 1–3):73–86.
DOI:10.1016/0378‐5173(82)90010‐2.
Patents
Kang, L*, SY Chan, JS Kochhar and WJ Goh, "Novel method to fabricate polymeric microneedles". USA: US patent office, 2015. http://patents.justia.com/inventor/lifeng‐kang Patent Publication number: 20150080802.
Kang, L*, SY Chan, JS Kochhar and WJ Goh, "A novel method to fabricate polymeric microneedles" China: China patent office, 2015. http://www.google.com/patents/CN104302349A?cl=en Patent Publication number: CN104302349 A.
Kang, L*, SY Chan, JS Kochhar and WJ Goh, "A novel method to fabricate polymeric microneedles 11201405643R". Singapore: Singapore patent office, 2014.
Kang, L*, SY Chan, JS Kochhar and WJ Goh, A novel method to fabricate polymeric Microneedles, WO2013137831 A1. Woden Act: Australian Patent Office, 2013.
Conference Proceedings
Li*, Y, WCA Chua, EHJ Kua, TT Phan, FP LIM, J Masilamani, SY Chan and HH Cheong, "Immuno‐privileged cord lining
epithelial cells for advanced wound repair ‐ a pilot in vivo study". International Society for Stem Cell Research
Annual Meeting (22 ‐ 25 Jun 2016, Moscone West, San Francisco, United States).
Chen*, CL, YJ Chong, SL Hie, R Sultana, SHD Lee, WSD Chan, SY Chan and HH Cheong, "Complementary and
Alternative Medicines use among pediatric epilepsy patients – Patterns and predictors". 15th Asian
Conference on Clinical Pharmacy (23 ‐ 26 Jun 2015, Ambassador Bangkok and Convention Center, Bangkok,
Thailand).
Chan, SY, JYC Lee*, E Kua and KZ Yap, "The Impact of psychotropic use monitoring (PUM) on inappropriate
prescribing of antipsychotics in a nursing home". Virtual Poster Symposium (2014). American College of
Clinical Pharmacy Virtual Poster Symposium, 20 ‐ 21 May 2014, ACCP, United States.
Kai Zhen Yap, Joyce Y. Lee, Ee Heok Kua, Sui Yung Chan: Psychotropic use monitoring for nursing home residents with
dementia. Annual Meeting of the American‐College‐of‐Clinical‐Pharmacy; 10/2012.
Peng Sun, Sui Yung Chan: Structural control and chemical functionalization of dual‐layer nanofiltration hollow fiber
membranes for efficient waste water treatment. North American Membrane Society Meeting 2012; 06/2012.
Wai Kiong Ng, Pei Liu, Prashant N. Balani, Sui Yung Chan, Reginald Tan: Mitigating electrostatic chargeability of
ibuprofen by wet co‐milling with polyvinylpyrrolidone. 2011 AIChE Annual Meeting; 10/2011.
Wai Kiong Ng, Vivian S.Y. Wong, Prashant N. Balani, Sui Yung Chan, Reginald B. H. Tan: Use of co‐milling to improve
physical stability of amorphous salbutamol sulphate. 2008 AIChE Annual Meeting; 11/2008.
Anandaroop Mukhopadhyay, Sui Yung Chan, Ivor J. Lim, David J. Phillips, Thang T. Phan: Activin system ‐ A potential
therapeutic target for keloid scar. 2nd International Congress on Regenerative Biology/2nd International;
04/2007.
K.Y.‐L. Yap, Chu Sing Lim, Sui Yung Chan, Yew Weng Chan: Rapid differentiation of pharmaceutical biomolecules:
Ginseng and adulterants. Biomedical and Pharmaceutical Engineering, 2006. ICBPE 2006. International
Conference on; 01/2007.
S/N
Status: PI, Co-PI, Collabor-
ator
Project Title (Project ID / Account No.)
by Chan Sui Yung
Funding Agency Amount Awarded (S$)
Duration of Award
(MM-YY) AcRF Non-AcRF
1 PI Evaluating a Novel Heart Health Screening and Intervention for the under-privileged communities in Singapore
Singapore Heart Foundation
- 40,000 7-16 to
6-18
2 PI Orodispersible Film Formulation for Paediatric Patients
R-148-000-210-112
ARF 81,195 - 7-15 to
7-18
3 PI Novel Transdermal Drug Delivery Systems for Neuropathic Pain
R-148-000-155-122
ARF 177,991 - 8-11 to
1-15
4 Co-PI New Membrane Development to Facilitate Solvent Recovery & Pharmaceutical Separation in Pharmaceutical Synthesis
R-706-000-019-592
& R-706-000-019-598 (IRC)
GSK-EDB - 840,000 12-11 to
11-14
5 Collaborator Nanoneedle Devices for Transdermal Vaccine Delivery
R-398-000-068-112
MOE 1,017,020 - 04.10 to
03.13
6 PI Implementing a monitoring tool in the nursing home to aid prescribing of psychotropic agents in residents with dementia
R-148-000-142-290
NUS VISA - 20,000 12-10 to
12-12
7 Co-PI NUS Initiative on Advanced Membranes forPharmaceutical & Biomedical Application
R-279-000-249-646
NUS 2,589,028 - 10-07 to
09-10
8 PI Formulation research on organogels and penetration enhancers for dermal drug delivery
R-148-000-093-112
ARF 129,384 - 02-07 to
08-10
9 PI The Human Skin Barrier and Its Intercellular Lipids
R-148-000-044-112
ARF 179,950 - 12-02 to
11-05
10 PI (replace- ment)
Drug-related problems in patients
R-148-000-036-112
ARF 67,000 - 11-01 to
11-04 11 PI Investigations on phytochemical agents for
wound healing
R-148-0000-029
ARF 106,000 - 12-00 to
12-02
12 PI Design & development of transdermal therapeutic systems for peri-operative applications
R148-0000-008
ARF 175,866 - 04-97 to
03-01
Updated on Nov 2016