Cryopreservation Innovative Solutions - LabXpertslabxperts.at/images/HerstellerPDFs/1_Panasonic... · Cryopreservation 4 Cryopreservation refers to the storage of a living organism,

Long term sample storage

Extreme temperatures require the most reliable equipment

Cryopreservation

Innovative SolutionsUltra-low -150ºC freezers, LN2 freezers

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LabXStampel

IntroductionGive your samples the best protection and first class preservation technology with Panasonic cryogenicfreezers. Our reputation is built on superior performance and reliability with uniform temperatures, evenin demanding environments with high ambient temperatures and frequent lid openings. Panasonic extreme-low freezers meet the toughest quality standards for performance, efficiency and construction.

We are proud to provide the ultimate and the most reliable protection for your samples, facilitating cutting-edge research in critical fields like medicine, life sciences, pharmaceuticals, biotechnology, andgeneral industrial use.

Discovery starts with a dream.A dream to know who we are. A dream to better our lives...Behind every great discovery, there’s the technology that made it all possible.

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Table of contents Features

Liquid nitrogen storageAccessoriesSpecifications

MDF-C2156VAN-PE MDF-1156-PE / MDF-1156ATN-PEIsothermal LN2 freezersIsothermal carousel Standard LN2 freezers 2101 Controlled rate freezer

81012161819

202225

Cryopreservation Solutions Best storage temperature uniformity. Dry storage systems.

Step into theworld of Cryopreservation

Liquid nitrogenstorage or dry storage?

ULTRA-LOW FREEZINGDRY STORAGE

STRAW STORAGE INVENTORY SYSTEM

2301 CONTROLLER

RACK CONFIGURATIONS

SELECT YOUR CRYOPRESERVATION SOLUTION

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15

6

4 5

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Panasonic Biomedical | Cryopreservation Solutions

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Step into the world of Cryopreservation

4

Cryopreservation refers to the storage of a living organism, cell or tissue atultra-low temperatures such that it can be restored to the same viable stateas before it was frozen. Storage for an indefinite amount of time requiressamples to be maintained below the glass transition temperature ofaqueous solutions, approximately -130ºC, the temperature at which frozenwater no longer sublimes and recrystallizes. Therefore -150°C mechanical freezers or liquid nitrogen storage tanks are requiredfor long-term preservation.

In the late 19th century Sir James Dewar, a Scottish chemist and physicist,designed a vacuum jacketed vessel capable of effectively storing liquidgases, such as nitrogen, for long periods of time. This type of vessel is stillbeing used today. For years cryopreservation in liquid nitrogen at -196°Chas been the standard for long term preservation.

Over the years it became clear that cross contamination was a real risk withthis kind of preservation. Not only can samples be contaminated by thenitrogen itself, but also by other samples. Evidence of cross contaminationhas been documented in the past, including a well known example ofHepatitis B transmission.

For this reason, storage in vapour phase became more popular. Valuablesamples were no longer stored in liquid phase nitrogen to eliminate the riskof cross contamination.

There are also disadvantages of storage in vapour phase though:1. Loss of storage capacity; The bottom third of the vessel cannot

be used as there is liquid phase nitrogen there.2. The temperature provided by vapour phase storage is highly dependent

on the level of liquid nitrogen in the bottom of the vessel.3. Large vertical temperature gradients can put valuable

samples at greater risk during long term storage.

Dry storage systems like -150ºC mechanical freezers and patentedIsothermal storage systems have been developed to offer the highest levelsof protection for valuable samples, without the risks of cross contaminationand vertical temperature gradients.

Hexagonal crystal

Cubic crystal

Amorphousice crystal

-80ºC

-130ºCRecrystallization

Point

-152ºC

Why freeze to -152ºC? Recrystallization mechanism

Liquid nitrogenstorage or dry storage?

Cross contaminationbecame a real riskwith this kind ofpreservation. Not only throughexisting ice, but fromsample to sample aswell.

19th century Insulated vesselsare first used forthe storage andtransport of liquidnitrogen.

No crosscontamination riskthrough LN2. No large vertical temperaturegradients.

Dry storage system

Temperature highlydependent on liquidnitrogen levels. Largevertical temperaturegradients.

Storage in vapourphase became more popular.


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Solution: Isothermals orultra-low -150ºC freezers

Panasonic is your ideal partner for extreme low temperaturestorage. By working in Europe with Custom Biogenic Systems,one of the leading manufacturers of innovative liquid nitrogenvessels, we are able to offer complete solutions forcryopreservation storage.

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Ultra-low -150ºC freezersDry storage

Panasonic Biomedical Sales Europe B.V. has established a worldwide reputation as amanufacturer of high quality medical equipment over the past forty years. During this time wehave become the leader in the European ultra-low temperature market. In this fieldPanasonic has set the standard in a number of ways including the introduction of VIP panels,Cool Safe® compressors and the world’s first -152ºC ULT freezer. Where Panasonic took theinitiative, the others followed. Together with the high standard of service we deliver it makesus a major player in the biomedical market.

Models: MDF-C2156VAN-PE, MDF-1156-PE

Due to the extended operation of compressors within ultra-lowtemperature freezers, lubricant oil is essential to reduce wear,prevent abrasions and seizure and therefore maintain the highestlevels of freezer performance. However, when lubricant oil circulateswithin the refrigeration circuit, it can cause piping to become clogged,resulting in compressor damage. Incorporating a high-efficiency oilseparator, Panasonic -150ºC freezers effectively separate lubricant oilfrom refrigerant, increasing the durability of the compressors andoffering a reliable ultra-low temperature environment.

Highly efficient compressors have been specially developed andincorporated our -150ºC freezers. The cascade refrigeration systemincorporating Cool Safe® compressors offers enhanced reliability andincreased sample security. With a powerful low noise design affordedby traditional ultra-low temperature technology, this freezer deliversdurable, stable cooling.

MDF-C2156VAN-PE

MDF-1156-PEULT -150ºCfreezers


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Umbilical cord blood as a source of

hematopoietic stem and progenitor cells.

Stem cells for autologous transplants in

patients who have undergone high dose

chemotherapy.

Adipose tissue, epithelial cells and bone

marrow for stem cell therapy.

Blood products for immunology analysis.

Mesenchymal stromal cells for regenerative

medicine and tissue engineering.

Cancerous tissue samples.

Semen for artificial insemination – used for

breeding guide dogs and race horses.

Oocytes and embryos for IVF.

Ovarian tissue for preserved reproductive

function in women undergoing treatments.

Plant seeds/shoots for breeding.

Components for shrink fitting of parts in

industrial manufacturing.

Temperature testing of parts in the automotive

and aerospace industry.

Panasonic’s -150°C ultra-low temperature freezers are already in use to store:

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MDF-C2156VAN-PELarge capacity -150ºC freezer

Third generation VIP insulationGraphic LCD displayCool Safe® compressorsNon-HCFC refrigerants

MDF-C2156VAN-PE 231 Litres, 150* - 2"boxes, 105 - 3"boxes* see page 23

Ultra-low -150ºC freezer with third generation VIPinsulation.The freezer is equipped with Panasonic developed thirdgeneration Vacuum Insulation Panels. This improved VIPinsulation is extremely efficient and results in a largecapacity -150ºC freezer for storage of up to 150 worldstandard 2" boxes with a minimal footprint.

Control panel with graphic LCD display.All alarm functions, self-diagnostic notifications and agraphical display of temperature performance over timeare available in the specially designed LCD controlpanel. The blue display provides a clear view of thetemperature and gives a notification in the case ofabnormalities in temperature, ambient temperature,power supply etc.

Cool Safe® compressors.The MDF-C2156VAN is equipped with Panasonic’s Cool Safe® compressors. These compressors achieve a10% reduction in energy consumption and theaerodynamically designed and placed components in therefrigeration compartment provide superior airflow,significantly reducing the stress to the freezer andcontributing to excellent durability.


9

1010

MDF-1156-PEStable long-term preservation of cells and tissues

Small footprintLow operating costCool Safe® compressors

MDF-1156-PE / MDF-1156ATN-PE 128 Litres, 81*- 2” boxes, 54 - 3” boxes

* see page 23


1111

Microprocessor control with LED digital displayallows accurate temperature setting and a stable -150ºC environment.Accurate temperature setting and a stableperformance are provided by a microprocessorcontroller with an easy to use LED digital display andflat key data entry. The MDF-1156 maintains an ultra-low temperature of -152ºC, far lower than therecrystallization point for pure water (-130ºC). This low temperature provides the ideal preservationenvironment for long-term storage.

Alarm and safety devices ensure high levels ofprotection for valuable samples.A high temperature alarm alerts users when thetemperature of the freezer deviates 10ºC or 15ºCabove the set temperature and a power failure alarmis activated if power to the freezer is lost. As well aslamp and buzzer functions, a remote alarm contactcan be set up to alert users to these abnormalitiesoutside of working hours. ATN models are also equipped with an auxiliary liquidnitrogen back-up system for added protection.

V-1500AB

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Isothermal LN2 freezersNo liquid nitrogen contactLiquid nitrogen is, like all liquids, a possible transporter of contaminants. Contaminationbetween samples, leakage of liquid nitrogen into sample vials during storage and contact ofliquid nitrogen with skin are just some of the risks that can be eliminated with an Isothermalliquid nitrogen dry storage freezer from Custom BioGenic Systems (CBS).

CBS Isothermal freezers feature a patented liquidnitrogen jacket to provide uniform storage temperaturesin the -190ºC range, free from liquid nitrogen contact.

In the year 2000 Custom Biogenic Systems patentedthe first -190ºC dry storage system. This new storagesystem uses the same vacuum insulated vessel asconventional LN2 freezers, but instead of the liquidnitrogen being in the sample storage space of thefreezer, it is in a patented liquid nitrogen jacket in thewall of the freezer. This liquid nitrogen jacket producesa unique vapour circulation in the freezer. This vapourcirculation, in combination with the convection fromthe freezer walls, produces a very stable temperaturein the -190ºC range without the large verticaltemperature gradients found in traditional vapourphase LN2 storage tanks. The minimal temperaturegradient and lack of liquid nitrogen in the bottom ofthe vessel means that the full internal volume of eachfreezer is available for storing samples at liquidnitrogen temperatures, making the most efficient useof capacity.

The innovative design of CBS Isothermal freezerseliminates a number of major risks of traditional LN2storage, including:l Cross contamination: Studies have shown that viral,bacterial and fungal pathogens can survive aftersuspension in liquid nitrogen. Infected samples cancross contaminate other samples in the same liquidnitrogen tank.l Loss of samples: Storage directly in liquid nitrogencan make vials shrink. This may cause liquid nitrogento seep into the vials, which on re warming, expand andsubsequently explode as nitrogen vapour izes insidethe vials. l Health and safety: Traditional storage in liquidnitrogen exposes users to direct contact with LN2which can lead to cold skin burns.

V-3000AB

Vacuuminsulation

Temperaturecontrolledstorage area

V-5000AB V-5000ABEH

Liquidnitrogenenvelope


13

The Isothermal conceptThe sample storage area iscooled by a liquid nitrogen jacketsurrounding the stainless steelinterior, and by nitrogen vapourentering the freezer from thejacket via directional vents. Thispatented technology providesexceptional temperatureuniformity in the -190°C range,allowing the full freezer capacityto be used with confidence. Thecirculation of vapour within thefreezer also results in less coldair loss during lid opening andimproved visibility. This allowsfull-width lids to be usedproviding quick, unrestrictedaccess to sample racks.

No liquid nitrogen contactWith no liquid nitrogen in thestorage area, samples can bestored safely in the -190°C rangewithout the risk of cross-contamination through liquidnitrogen. The Isothermal designalso provides added user safetywith no splashing or contact ofliquid nitrogen when removingracks and samples from thefreezer.

All Isothermal models are certified to Medical Device Directive93/42/ECC: 1993 Class IIA

Automatic operationIsothermal freezers feature the series 2301 auto-fill and monitorsystem, which controls the automatic filling of the liquid nitrogenjacket and provides the user with an easy to read overview of thefreezer temperature and status.

Sample securityA comprehensive alarm system with remote alarm contactconstantly monitors all aspects of the freezer’s operation. Samplesare also protected by lid and control panel locks. The freezer canbe monitored by a central BMS or monitoring system.

Sample storageA wide selection of inventory systems for vials and bags areavailable to complete the system and optimize sample storage.

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-195˚C

-190˚C

Rotating carousels provide access to lower storage levels and maximise storage space.

The upper level provides a convenientworkspace where canisters can beparked (shown in green) and samplesinspected at -190°C.

Use the retrieval tool to place and retrieve canisters quickly and easily.

Straw storage inventory systemDesigned for the CBS V-1500AB and V-3000AB Isothermal freezers,this patent-pending inventory system provides an efficient solution forstoring and working with straws, free from liquid nitrogen contact.

FeaturesCompatible with all on site automated LN2 supply systemsAvailble on all standard and Isothermal LN2 freezersProgramming of LN2 auto-fill levels and cyclesSequential filling capabilities, one-fill-all-fillWarm gas by-passOutput data to PC / printer (USB port and printer port)RS-485 communication portCryomonitor software for freezer function andalarm downloadSystem validation with print outKey pad lockLid lock

Front panel displaySystem status displayLiquid level inches / centimetersTwo level temperature display; at lid and insidestorage spaceSystem status start / stop fill

AlarmsVisual, audible and remoteHigh and low LN2 levels in jacketTemperature deviationSensor and valve abnormalityLN2 source / supplyRemote alarm contactOverflow sensor/alarm (optional)

2301 Controller


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Isothermal carouselEasy access to samples from the front of the freezer

The Isothermal carousel liquid nitrogen vapour storage system combines the innovative -190°C Isothermal design with a small opening and an interior rotating carousel. The smallopening provides low liquid nitrogen consumption, a lightweight, user-friendly lid and aconsistently low temperature in the freezer. The interior carousel is rotated by a uniqueratcheting handle on top of the freezer that will position samples to the front of the freezer,even with the lid on.

Each Isothermal carousel system includes theadvanced 2301 auto- fill/monitoring controller toprovide security and ease of operation. There areseveral Isothermal carousel models available andan extensive selection of inventory racks to storeany size tube, vial, box, microplate, etc. to completethe system. Custom configurations can also bedesigned to meet any requirement.

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S-3000AB/C

No need to remove one rack to retrieve another rack.No unnecessary exposure to room temperatures.Carousel is rotated from the outside of the freezereliminating the risk of injury or temperaturefluctuations.Exceptional temperature uniformity.Easy access to samples from the front of thefreezer.Removable console allows for complete access tothe sample storage space if necessary.

CBS Isothermal carousel freezers are cooled by apatented liquid nitrogen jacket, with no liquid in thesample storage space.No risk of cross-contamination through liquidnitrogen contact.No need for special packaging for files.The isothermal design also provides added user-safety eliminating contact or splashing ofliquid nitrogen.Manufactured to ISO 13485 standards.


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Standard square rack configuration 1500AB

Five liquid nitrogen freezers are available ranging insizes from 90 litres to 720 litres, with sample storagecapacities up to 40,000 2 ml vials or over 3,500 bloodbags. Each unit includes a liquid level auto-fill and alarmsystem to provide security, ease of operation, plusflexibility to operate as vapour storage, immersionstorage or a combination of both to store any type or sizeof sample. An extensive selection of standard inventoryracks or canisters and frames are available to completethe system. Custom configurations can also be designedto fit any requirements.

Standard LN2 freezers include the 2301 controller

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Standard LN2 freezersStandard liquid nitrogen freezers are designed to meet temperature,storage and security specifications required by laboratories storingfrozen samples at cryogenic temperatures.

S-90AB

S-5000ABEH

S-1500AB

S-3000AB

Standard system Includes:l Laptop computer with 2100 softwarel Freezing chamberl Choice of sample rack l 1.2 m LN2 transfer hose

Options:l Choice of sample racks for vials,

tubes, straws, bags & canesl Temperature probes for different

sample typesl Roller cart

Unlimited programming capabilityMulti-colour graph for sample, chamber andprogram temperatureSample or chamber temperature set-point controlContinuous control status indicationPrograms and freeze data saved to hard drive or discPassword protected softwareSelectable password levelsSearchable database for freeze run history

Freeze run graphs and data available via anystandard computer printer30 data field available for each freeze runContinuous digital and graphical display of time and temperature during operationAudible and visual indicators for:l End of each freeze run l Temperature probes l Freeze run trackingOn screen help

The 2101 controlled rate freezer meets the highest standards for the programmed freezingof biological samples. Computer controlled temperatures ensure your samples are frozenat precisely the same rate during each run. Freeze protocols can be controlled by eitherthe chamber or the sample temperature. The freezing rate can be programmed at theoptimum rate for each individual sample.

The 2101 controlled rate freezer comes equipped with a dedicated laptop and 2100 programming softwareas standard to provide the highest levels of flexibility and user convenience.

Benefits include:

2101 Controlled rate freezer


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2101 controlled rate freezer

Manual-fill cryosystems provide versatile,low cost sample storage at cryogenictemperatures with maximum capacity andlow liquid nitrogen consumption.

Vapour shippers are designed for the safetransportation of biological samples atcryogenic temperatures.

Manufactured from durable, lightweightaluminum, the shippers contain a compoundwhich absorbs the liquid nitrogen to ensure dry,spill-free vapour-phase shipping. The absorbentalso repels moisture and humidity, assuring themaximum holding time.

A protective shipping carton is available for allmodels which protects the container from beingplaced on its side and helps in withstanding therigors of transportation. These containers can beused to ship your samples with a "non-hazardous" classification throughout the world.

Vapour shippers

Cryosystems - Liquid nitrogen storage‘XC’, ‘Classic’ and ‘Value Added’ series fulfil awide range of storage requirementsCapacities from 210 to 6,000 2ml vialsAdvanced vacuum and insulation for maximumthermal performanceDurable, lightweight aluminium construction androller bases for easy mobilityStorage solutions for vials and strawsEasy access to store and retrieve samplesSample security with low-level alarm and lockablelids (padlock not supplied)

‘XC’ series – Compact cryosystems for vial or strawstorage. With roller base and handle mounted lowlevel alarm.

‘Classic’ series – Medium capacity storage for vialsin standard cryogenic boxes. With roller base andhandle mounted low level alarm.

‘Value Added’ series – Same as ‘Classic’ series butwith the low level alarm built into a lid console.

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Value Added 2001

Classic 4002

CS 4/3V

DS-3

The CF-9511 transport containeris a high-quality unit, primarilyfor use in moving samples overshorter distances, such as fromone lab to another.

The LAB series dewars usehigh efficiency super-insulationand aluminum construction tomake them lightweight and themost efficient containersavailable. Their shape andhandles make them easy to liftand pour. The LAB seriesdewars can also be fitted withpouring spouts, withdrawaldevices, or dippers to aid inliquid nitrogen transfer.

Lab-Tanks


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LAB 4

LAB 10

LAB 50

LAB 30

Standard square rack configuration 3000AB

Vertical rack configuration 5000AB

3101A-100S

Rack configurations

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For other sizes racks and boxes, canisters and inventory systems visit our website Capacity is subject to rack type

Boxes and dividersl Standard 2” and 3” boxes are available, in sturdy moisture resistantcardboard.

l For the XC series cryosystems we have the smaller 2” miniboxincluding a 25 cell divider (B2CM + D25M).

l Sturdy cardboard cell dividers come in a wide selection of sizes toaccommodate the storage of a variety of tubes and vials.


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Vertical racks for ULT -150 Freezers

MDF-1156-PE NIR-209C Aluminium rack system (cardboard boxes and dividers are optional) compromises 9 racks x 9 boxes high. Cap. 8.100 2ml. vials.TE-NIR-210COM Stainless steel rack system (cardboard boxes and divider are optional) comprises 9 racks x 10 boxes high. Cap. 9000 2ml. vials.

MDF-C2156VAN-PE NIR-210C Aluminium rack system (cardboard boxes and dividers are optional) compromises 15 racks x 10 boxes high. Cap. 15.000 2ml. vials.TE-NIR-211COM Stainless steel rack system (cardboard boxes and divider are optional) comprises 15 racks x 11 boxes high. Cap. 16,500 2ml. vials.

Standard square racks

V-1500AB 2001A-100S Aluminium rack system with cardboard boxes + dividers.

S-1500AB 2001S-C81 Comprises 7 racks x 13 boxes high. Max. cap. 9.100 2ml vials.


S-3000AB 3101A-100S Comprises 17 racks x 13 boxes high. cap. 22.100 2ml vials.


S-5000AB 3301A-100S Comprises 28 racks x 13 boxes high. cap. 36.400 2ml vials.

V-5000ABEH 3325A-100S Aluminium rack system with cardboard boxes + dividers.

S-5000ABEH 3325A-100S Comprises 28 racks x 15 boxes high. cap. 42.000 2ml vials.

Vertical racks

V-1500AB RC-V1500-1209-VLR Stainless steel rack system with cardboard boxes + dividers.

S-1500AB RC-S1500-1209-VLR Comprises 20 racks x 5 boxes high. cap. 10.000 2ml vials


S-3000AB RC-S3000-1209-VLR Comprises 48 racks x 5 boxes high. cap. 24.000 2ml vials"


S-5000AB RC-S5000-1209-VLR Comprises 80 racks x 5 boxes high. cap. 40.000 2ml vials

V-5000ABEH RC-V5000EH-1208-VLR Stainless steel rack system with cardboard boxes + dividers.

S-5000ABEH RC-S5000EH-1208-VLR Comprises 80 racks x 6 boxes high. cap. 48.000 2ml vials

Accessories for Isothermals, LN2 freezers & cryosystems

1. Cryo-GlovesMade from state-of-the art fabrics,tempshield Cryo-gloves® use a flexible,multi-layered insulated construction thatprovides maximum thermal protection,yet offers comfort, flexibility, and dexterityso you can perform tasks effectively andsafely. An additional stay-dry lining keepsyou warm and comfortable. Cryogenicgloves protect your hands and arms whenworking in hazardous, ultra-coldenvironments. An essential feature whenfunction is important and safety iscritical. Styles include: shoulder, elbow,mid-arm, and wrist US sizes: small,medium, large, extra-large EN sizes: 8, 9,10, 11.

2. “T” Valvel Solid brass cryogenic shut-off valve

(rated for temperatures from -196° C to 74° C)

l 2 Male 1/2” NPT brass fittingsl 1 Female 1/2” NPT stainless steel

Flared fittingl Overall length approximately 11”

3. “Y” Valvel 2 Male 1/2” NPT brass fittingsl 1 Female 1/2” NPT stainless steel

flared fittingl Overall length approximately 6”

4. LN2 Phase separatorDesigned to minimize hazardoussplashing and vapourization, phaseseparators are available to use whentransferring liquids into various opencontainers.

5. LN2 Level stickl 1/2 Centimeter and 1/4 inch

incrementsl Can withstand temperatures up to

-190°Cl Measures up to 36”(92cm)

6. LN2 Transfer hosel Flexible stainless steel constructionl 1/2” NPT flared fitting on both ends

(3/8” I.D.)l 4’, 6’ lengths are available (custom

lengths are available upon request)

7. Cardboard sleevesl 5 and 6 place sleeves for standard

2ml canel Cardboard construction

8. Roller baseCryosystem roller bases. Reinforcedfiberglass construction with casters.5 configurations available: 15” (magenta), 18” (blue), 18” (white, heavy duty), 20” (magenta), 22” (blue), 26” (blue)

9. Canesl 2ml canel 5 and 6 place vial canesl Lightweight aluminum constructionl Overall length approximately 11.5” (6

place cane)

10. Hose coversl Water resistant fabric 4', 6' lengths

are available

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1. 2. 3. 4.

5. 6. 7. 8.

9. 10.

Specifications

600

1400

94557

266

7

450400

800

Dimensions MDF-1156

1010

1730

1125

760

615

11.5

53

495

465

802

105

924

765 46864

Dimensions MDF-2156VAN

notes:1) Exterior dimensions of main cabinet only - see dimension drawings showing handles and other external projections 2) Depending on which rack is used, see page 23.3) Air temperature measured at freezer centre, ambient temperature +30ºC, no load4) Nominal value. Background noise 20dB.5) Requires recorder MTR-155H-PW6) CVK-A-PW may also be used

Pro series freezers -150°C/-152°C

PUF = Rigid polyurethane foamed insulation

V = Visual alarmB = Buzzer alarmR = Remote alarm

GROUP

230V 50Hz single

Microprocessor, non-volatile memory

1100HFC1100

HFC mixed

Painted steelAluminium

Appearance and specification are subject to change without notice.


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Characteristics

MODEL

DimensionsExternal dimensions (W x D x H)1)Internal dimensions (W x D x H)VolumeCapacity Net weight (approx)PerformanceCooling performance 3)Temperature setting rangeTemperature control range 3)ControlControllerDisplayTemperature sensorRefrigerationRefrigeration system

High-stage compressorHigh-stage refrigerantLow-stage compressorLow-stage refrigerantInsulation materialInsulation thicknessConstructionExterior materialInterior materialOuter lid lockInner lidMax. load - totalAccess port- position- diameterCastersAlarmsPower failureHigh temperatureLow temperatureFilterLid openElectrical and Noise LevelPower supplyNoise level 4)OptionsInventory racksLiquid CO2back-upLiquid N2 back-upTemperature recorders- Continuous strip type- Chart paper- Ink pen- Recorder housing (if required)RS485 interface moduleStorage case

mmmmlitres2” Boxeskg

ºCºCºC

W

W

mm

qtykgqty

Ø mmqty

dB

MDF-1156-PE

1400 x 800 x 945500 x 450 x 572

12881 / 90 2)265

Y13001left40

6 (2 leveling feet)

V-B-RV-B-R-V-B-

61

See page 23CVK-AT2-PW 5,6)CVK-ATN2-PW 5)

MTR-155H-PWRP-155-PWDF-38FP-PW

--

MDF-49SC-PW

MDF-1156ATN-PE

1400 x 800 x 945500 x 450 x 572

12881 / 90 2)272

Y13001left40

6 (2 leveling feet)

V-B-RV-B-R-V-B-

61

See page 23-

Supplied as standard

Supplied as standardRP-155-PWDF-38FP-PW

--

MDF-49SC-PW

MDF-C2156VAN-PE

1730 x 765 x 1010760 x 495 x 615

231150 / 165 2)

318

-150-125 ~ -152-125 ~ -150

LCDPt-1000

Cascade with auto-cascade low-stage

PUF / VIP PLUS135

Y22071

right40

6 (3 leveling feet)

V-B-RV-B-RV-B-RV-BV-B

51

See page 23-

Supplied as standard

MTR-155H-PWRP-155-PWDF-38FP-PW

MDF-S30150-PWMTR-480-PWMDF-49SC-PW

-152-125 ~ -155-130 ~ -152

LEDPt-100

Cascade

PUF175

GROUP

MODELLiquid nitrogen capacityDimensionsExternal dimensions (WxDxH)Usable interior height Usable interior diameter Weight emptyWeight fullMaximum capacityMax. vial capacity (2ml)**Max. blood bag capacity (50ml)**

**Capacity is subject to rack type

Standard LN2 freezers

GROUP


litres

mmmmmmkgkg

litres

mmmmmmkgkg

V-1500AB30

660 x 939 x 1143736534148174

9100434

V-3000AB70

939 x 1219 x 1206736787272327

221001120

V-3000ABEH89

939 x 1219 x 1473940787295367

255001280

V-5000AB93

1219 x 1371x13207361016425500

403001936

V-5000ABEH140

1219 x 1371 x 14738641016453566

465002208**

Capacity is subject to rack type

S-90AB90

457x 457x 96571140636109

5832266

S-1500AB145

558x 787x 104173650870188

9100434

S-3000AB345

863x 1092x 1066736787159438

221001120

S-5000AB615

1117x 1320x12197361016227724

403001932

S-5000ABEH720

1117x 1320x13978631016245827

465002208

MODELLiquid nitrogen capacityStatic evapouration rateStatic holding time Working volume Weight emptyWeight fullDimensionsNeck opening Overall height Outside diameterCanister dimensionsCanister height Canister diameterMaximum capacityMaximum number of racksMaximum vial capacityMaximum number of canistersMaximum boxes per rackMaximum number of 1/2cc straws (10/cane) Maximum number of 1/2cc straws (1 level bulk)Maximum number of 1.2 & 2.0 ml vials (5/cane)AlarmLow-level alarm

litres ltr/daydayslitres kgkg

mmmmmm

mmmm

qty

qty

Classic 2002610.85385126.382.5

216723559

--

42000-5-

-

-

standard

Classic 40021210.997011136.7136

2161003559

--

44000-10-

-

-

standard

Classic 60021750.9910416546.7193

2161003665

--

66000-10-

-

-

standard

Value added2001610.85385126.382.5

216723559

--

42000-5-

-

-

standard

Value added40011210.997011136.7136

2161003559

--

44000-10-

-

-

standard

Value added60011750.9910416546.7193

2161003665

--

66000-10-

-

-

standard

20/2020.50.09140

11.828.3

55.4652368

27941.9

--6-780

1122

210

standard

34/1834.80.18123

15.443.5

89675464

27971

--6-

2100

3000

630

standard

47/1147.40.3976

16.454.6

127673508

279102

67506-

4500

6216

1320

standard

Classic XC series

Isothermal -190ºC dry storage freezers

GROUP Value added

26

MODELLiquid nitrogen capacityStatic evapouration rate Static holding time Weight emptyWeight fullNumber of canistersMax vial capacity (2ml)Unit dimensionsNeck openingOverall heightOutside diameterUsable interior dimensionsInterior heightInterior diameterCanister heightCanister diameter

SC 2/1 V1.50.1982.7419

35343184

--12731

SC 4/2 V3.60.26135.98.11106

70468222

--27867

SC 4/3 V4.30.202113.99.3148

51492222

--27846

DS-3100.71413.621.3-500

216584381

317.5216--

CF-951110.53.335.914.5--

228.6431.8254

228.6228.6--

litresltr/daydayskgkg

mmmmmm

mmmmmmmm

GROUP Vapour shippers Shipper

Appearance and specification are subject to change without notice.

GROUP

MODELDimensionsExterior (W x D x H)Interior (W x D x H)Effective capacityWeightPowerVoltageFrequencyCurrentMaximum capacity2ml vials4ml / 5 ml vialsBag canistersCanes

mmmmlitreskg

2101

484 x 648 x 743356 x 243 x 349

2834.7

230V50 Hz10A

65039020130

GROUP


litres

mmmmmmkgkg

**Capacity is subject to rack type

Lab440.2182.76

35.5426185

139198

Lab55

0.1533.348

56462222

165266

Lab10100.1855.6614

56546260

210343

Lab20210.18116.7926

51627368

289348

Lab30320.251281238

64611432

356378

Lab50500.451111556

64779432

356559

litres ltr/daydayskgkg

mmmmmm

mmmm

GROUP

Isothermal carousel

V-3000AB/C70

939 x 1219 x 1130686736272327

16800852

V-3000ABEH/C89

939 x 1219 x 1384889736288361

210001136

V-5000AB/C93

1194 x 1372 x 1257737978425499

364001722

V-5000ABEH/C140

1194 x 1372 x 1384813978452566

420001968

Controlled rate freezer

MODELLiquid nitrogen capacityStatic evapouration rate Static holding time Weight emptyWeight fullExterior dimensionsNeck opening Overall heightOutside diameter Interior dimensionsInterior diameterUsable height

Lab tanks


27

©2015 Panasonic Biomedical Sales Europe B.V.Publication Number: 23698

S-Series S-Series Cryo- V-Series ULT Freezersliquid vapour systems -190ºC -150ºC / -152ºC

Storage in ULT-Freezer xStorage in dry vapour of LN2 xStorage in liquid phase of LN2 x xStorage in vapour phase of LN2 xRisk of cross contamination through LN2 x xNo risk of cross contamination through LN2 x x xLarge temperature gradient risk xSmall temperature gradient risk x1 x1 x xAssured storage below critical temperature of -130°C x1 x1 x xAutofill and monitoring required x x x not applicable

No autofill and monitoring required x not applicable

Storage of more than 6000 2ml vials x x x xStorage of less than 6000 2ml vials xEase of handling racks x xUsage of LN2 low moderate low moderate none

No special requirements needed in storage room x

x1 Only when the LN2 level in the tank is maintained at the specified required level

Select your Cryopreservation solution

Panasonic Healthcare Co., Ltd., Gunma factory is certified for:Quality management system: ISO9001 / Medical devices quality management system: ISO13485 / Environmental management system: ISO14001

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Documents

Cryopreservation Innovative Solutions - LabXpertslabxperts.at/images/HerstellerPDFs/1_Panasonic... · Cryopreservation 4 Cryopreservation refers to the storage of a living organism,