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CREIERUL HOLISTIC
The Universe may turn out to be infinite in extent and full of alien worlds beyond imagination but current scientific thinking suggests that we need it all in order to exist
Wonders of the Universe Professor Brian Cox amp Andrew CohenHerperCollins e-books
At 137 billion years old 45 billion light years across and filled with 100 billion galaxies ndash each containing hundreds of billions of stars ndash the Universe as revealed by modern science is humbling in scale and dazzling in beauty But paradoxically as our knowledge of the Universe has expanded so the division between us and the cosmos has melted away
By early 2011 we had discovered that the Universe is composed of twelve basic building blocks only three of which are required to build everything on our planet including our bodies These three components known as the up and down quarks and the electron can be assembled into the more familiar protons and neutrons ndash two up quarks and a down quark make a proton and two down quarks and an up make up a neutron -
The oldest version comes from the Rig Veda 4000 BCE In the Hymn 129 says ldquoThen was not non-existent nor existent there was no realm of air no sky beyond ithellipThat One Thing breathless breathed by its own nature apart from it was nothing whatsoever
COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
Upanishads- 1000 and 500 BCE- ldquoThe universe comes forth from Brahman and will return to Brahman- ultimate reality existing out of space and time from which everything springs and of which everything consists it is generally interpreted as the Cosmic Consciousness or Spirit or Supreme Godhead beyond all form COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
The Universe may turn out to be infinite in extent and full of alien worlds beyond imagination but current scientific thinking suggests that we need it all in order to exist
Wonders of the Universe Professor Brian Cox amp Andrew CohenHerperCollins e-books
At 137 billion years old 45 billion light years across and filled with 100 billion galaxies ndash each containing hundreds of billions of stars ndash the Universe as revealed by modern science is humbling in scale and dazzling in beauty But paradoxically as our knowledge of the Universe has expanded so the division between us and the cosmos has melted away
By early 2011 we had discovered that the Universe is composed of twelve basic building blocks only three of which are required to build everything on our planet including our bodies These three components known as the up and down quarks and the electron can be assembled into the more familiar protons and neutrons ndash two up quarks and a down quark make a proton and two down quarks and an up make up a neutron -
The oldest version comes from the Rig Veda 4000 BCE In the Hymn 129 says ldquoThen was not non-existent nor existent there was no realm of air no sky beyond ithellipThat One Thing breathless breathed by its own nature apart from it was nothing whatsoever
COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
Upanishads- 1000 and 500 BCE- ldquoThe universe comes forth from Brahman and will return to Brahman- ultimate reality existing out of space and time from which everything springs and of which everything consists it is generally interpreted as the Cosmic Consciousness or Spirit or Supreme Godhead beyond all form COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
At 137 billion years old 45 billion light years across and filled with 100 billion galaxies ndash each containing hundreds of billions of stars ndash the Universe as revealed by modern science is humbling in scale and dazzling in beauty But paradoxically as our knowledge of the Universe has expanded so the division between us and the cosmos has melted away
By early 2011 we had discovered that the Universe is composed of twelve basic building blocks only three of which are required to build everything on our planet including our bodies These three components known as the up and down quarks and the electron can be assembled into the more familiar protons and neutrons ndash two up quarks and a down quark make a proton and two down quarks and an up make up a neutron -
The oldest version comes from the Rig Veda 4000 BCE In the Hymn 129 says ldquoThen was not non-existent nor existent there was no realm of air no sky beyond ithellipThat One Thing breathless breathed by its own nature apart from it was nothing whatsoever
COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
Upanishads- 1000 and 500 BCE- ldquoThe universe comes forth from Brahman and will return to Brahman- ultimate reality existing out of space and time from which everything springs and of which everything consists it is generally interpreted as the Cosmic Consciousness or Spirit or Supreme Godhead beyond all form COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
By early 2011 we had discovered that the Universe is composed of twelve basic building blocks only three of which are required to build everything on our planet including our bodies These three components known as the up and down quarks and the electron can be assembled into the more familiar protons and neutrons ndash two up quarks and a down quark make a proton and two down quarks and an up make up a neutron -
The oldest version comes from the Rig Veda 4000 BCE In the Hymn 129 says ldquoThen was not non-existent nor existent there was no realm of air no sky beyond ithellipThat One Thing breathless breathed by its own nature apart from it was nothing whatsoever
COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
Upanishads- 1000 and 500 BCE- ldquoThe universe comes forth from Brahman and will return to Brahman- ultimate reality existing out of space and time from which everything springs and of which everything consists it is generally interpreted as the Cosmic Consciousness or Spirit or Supreme Godhead beyond all form COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
The oldest version comes from the Rig Veda 4000 BCE In the Hymn 129 says ldquoThen was not non-existent nor existent there was no realm of air no sky beyond ithellipThat One Thing breathless breathed by its own nature apart from it was nothing whatsoever
COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
Upanishads- 1000 and 500 BCE- ldquoThe universe comes forth from Brahman and will return to Brahman- ultimate reality existing out of space and time from which everything springs and of which everything consists it is generally interpreted as the Cosmic Consciousness or Spirit or Supreme Godhead beyond all form COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Upanishads- 1000 and 500 BCE- ldquoThe universe comes forth from Brahman and will return to Brahman- ultimate reality existing out of space and time from which everything springs and of which everything consists it is generally interpreted as the Cosmic Consciousness or Spirit or Supreme Godhead beyond all form COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
According to the Standard Theory an elementary particle of matter can spontaneously materialize from an energy field together with its symmetrically opposite particle of antimatter which has the same mass and spin but opposite charge Thus an electron (negatively charged) appears with a positron (positively charged) and a proton (positively charged) with an antiproton (negatively charged)COSMO SAPIENS Human Evolution from the Origin of the UniverseJOHN HANDS Overlook Duckworth Peter Mayer Publishers Inc 2015
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
rdquohelliplegile mecanicii cuantice implică faptul
că la scări foarte mici pentru perioade foarte scurte spațiul vid poate părea a fi o fiertură clocotitoare de particule virtuale și cacircmpuri care fluctuează haotic icircn mărime Aceste rdquofluctuații cuanticerdquo pot fi importante pentru determinare caracterului protonilor și atomilorhellip
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
hellipfluctuațiile de mică densitate din spațiul
vid datorate regulilor mecanicii cuantice vor fi mai tacircrziu responsabile pentru icircntreaga structură pe care o observăm icircn Universul de astăzi Așa icircncacirct noi și tot ceea ce vedem suntem rezultatul fluctuațiilor cuantice produse icircn ceea ce este icircn mod esențial nimicul din apropierea icircnceputului timpului și anume din timpul expansiunii inflaționisterdquo
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
hellipasimetria materie-antimaterie ndash dacă
universul nostru ar fi avut un icircnceput logic cu cantități egale de materie și antimaterie și ar fi rămas așa noi nu ne-am aflat aici ca să ne icircntrebăm De ce sau Cum hellip toate particulele de materie s-ar fi anihilatcu toate particulele de antimaterie icircn universul timpuriu nelăsacircnd nimic altceva decacirct radiație pură ndashfotonii Radiația Cosmică de Fond de Microunde
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
hellipceea ce altfel ar putea să pară o realizare
măruntă (stabilirea unei mici asimetrii icircn perioada incipientă) ar putea fi de fapt considerat aproape ca momentul creațieiFotonii RCFM sunt icircn acest model rămășițele anihilărilor timpurii dintre materie și antimaterie de pe la icircnceputul timpului
L M Krauss Universul din nimic Ed TREI 2013
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
ldquoThe whole Universe was once an incubator for liferdquo
Life possible in the early Universe Zeeya Merali
NATURE December 2013
De la Informație la Viață
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Toate-s vechi si noua toate -M Eminescu
The brain is a kludge - David J Linden
Creierul ndash poarta dintre Univers şi Omenire
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
The brain is to use one my favorite word a kludge a design that is inefficient inelegant and unfathomable but that nevertheless works David J Linden The Accidental Mind How Brain Evolution Has Given Us Love Memory Dreams and God
David J Linden is a Professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Modern golgi staining YFP mouse
cortical fluorescence can be bred
to other KOrsquos transgenics Feng et al 2000
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Differences in connectome wiring
between men (above) with
predominantly intra-cortical
connections (blue) within each lobe
while women (below) have significant
inter-cortical connection (orange)
The results establish that male brains
are optimized for intrahemispheric and
female brains for interhemispheric
communication The developmental
trajectories of males and females
separate at a young age demonstrating
wide differences during adolescence
and adulthood The observations
suggest that male brains are structured
to facilitate connectivity between
perception and coordinated action
whereas female brains are designed to
facilitate communication between
analytical and intuitive processing
modesIngalhalikara et al 2013 PNAS wwwpnasorgcgidoi101073pnas1316909110
Different connectome wiring
between men and women
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Repere istorice
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
-Hipocrate- 460 icircc susţinătorul
observaţiei clinice
ldquocreierul- cel mai puternic organ
al corpuluirdquo
- Aristotel 384-322 icircc- inima
sediul mişcării si vieţii psihice
-Tinexcitabilităţii cerebrale 1870
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
- Medicul regelui Filip cel frumos după
1300 scrie ldquocreierul este rece şi umed
pt a diminua extrema căldură şi
uscăciune a inimii alb pt a fi ca o tabula
rasa şi a primi orice imagine lax şi
moderat de vacircscos pt ca lucrurile
percepute să-l străbată uşor
- Abu Ali Ibn Sina (Aviccena)-980-1037
scrie ldquoCanonul Medicineirdquo sau
ldquoIcircndreptarul de ştiinţe medicalerdquo 1700
- a realizat prima nevroză experimentală
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
- W Harvey 1628 ndashrdquoDe motu
cordis et sanguinis in animalibusrdquo
- Guy Patin ldquocirculaţia sacircngelui
este paradoxală imposibilă
absurdă şi nocivă vieţii omuluirdquo
- Antony van Leeuwenhoek -
1612- microscopul optic
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
- Haller-1727-presiune volum
sangrdquoanatomia face descrierea
organelor iar fiziologia explică
funcţiile lor
- Malpighi- 1661- capilar sangvin
Suport chimic
Paracelsus ndash 1493-1541
Lavoisier - 1743-1794
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Mendel ndash ldquoExperienţe asupra
hibridizării plantelorrdquo
Cl Bernard 1865 Introducere
icircn studiul medicinei
experimentale
Suport electric- L Galvani 1791
1865
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
W Waldeyer ndash 1891 ndash neuronul
Bayliss Starling 1902 - secretina
CGolgi RCajal 1906 ndash
teoria reticulară - neuronală
D Robertson E Robertis
G Palade- 1950 -teoria neuronală
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
- Walter Sutton 1902 ndash teoria
cromozomială a eredităţii
- W Bateson 1902- genetică
- Hans Wincler 1920- genom
CWaddington1939- epigenotype
J Watson Fr Crick ndash 1953 ADN
Genomul uman 2003
Proiect BRAIN 2013
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
ldquoEu Socrate am icircnvăţat această incantaţie (descacircntec) acolo icircn oaste de la un medic trac unul dintre ucenicii lui Zamolxishellip Spunea tracul acela că Zamolxis care este şi un zeu ne icircnvăţa că după cum nu trebuie să icircncercăm a trata ochii fără să ţinem seama de cap nici capul nu poate fi tratat neţinacircn-du-se seama de corp tot astfel trebuie să-i dăm icircngrijire trupului dimpreună cu sufletulhellip
Platon - Dialogul despre icircnţelepciune cu Charmides
Socrate 470-399 Platon 427-347 Aristotel 384-322 Hipocrate 460-370 icirc e n
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Sociodemografic lifestyle psycho-social stress and metabolic and physiological stress factors are cross-sectionally linked with telomere lenght (TL) TL has been associated with aging and mortality
D Revesz et al Baseline biopsychosocialdeterminants of telomere lenght and 6-years attrition rate Psychoneuroendocrinology 67 2016
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
The beneficial effects of lautgher hellip are strongly suggested in terms of normalizing the expression of the prorenine receptor gene followed byreducing the levelof blood prorenine
Hayash T et all Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes Journal of Pshychosomatic Research (62)2007
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
These results suggest that the laughter influences the expression of many genes classified into immune responses and may contribute to amelioration of postprandial blood glucose elevation through a modulation of NK cell activitycaused by up-regulation of relating genes
Hayashi T et allLauther up-regulates the genes related to NK cell activity in diabetes Biomedical Research (28) 2007
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
In transgenerational epigenetic inheritance phenotypic information not encoded in DNA sequence is transmitted across generations In germline-dependent mode memory of environmental exposure inparental generation is transmitted through gametes leading to appearance of phenotypes in the unexposed future generations The memory is considered to be encoded in epigenetic factors like DNAmethylation histone modifications and regulatory RNAs
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma The latterpossibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma not in reverse As such identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
It is in this context that we would liketo consider the genomic ldquodarkmatterrdquoone of the major mysteries of the post-genome era Perhaps no other topic incontemporary genomics has inspired such diverse viewpoints as the 95+ of the genomepreviously known asldquojunk DNArdquo that does not code forproteins
Transgenerational epigenetic inheritance Focus on soma to germline information transfer A Sharma Progress in Biophysics and Molecular Biology (2012)
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
A semi-synthetic organism with an expanded genetic alphabetMalyshev DA Dhami K LavergneT Chen T Dai N Foster JM CorrecircaIR Jr Romesberg FE Nature 2014 May 15
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
This paper argues that at least one of the following prepositions is true (1) the human species is very likely to go extinct before reaching a posthuman stage (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of their evolution history (or variations of thereof)
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Bostrom N Are you living in a computer simulation-PhilosophicalQuarterly (2003) Vol 53 No 211 pp 243-255
(3) we are almost certainly living in a computer simulation It follows that the belief that there is a significant chance that we will one day become potshumans who run ancestor- simulations is false unless we are currently living in a simulation
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Cunoașterea actuală se icircndreaptă către o
realitate non-mecanică Universul icircncepe să semene din ce icircn ce mai mult cu un mare gacircnd decacirct cu o mașinăriehellip Mintea pare că nu mai este doar un intrus accidental icircn tăracircmul materieihellip mai degrabă am privi-o ca pe creatoarea și guvernatoarea planului fizic
Sir James Hopwood Jeans The Mysterious Universe Cambridge University Press 1930
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
rdquoIdeologeis philosophies religious doctrines world-models value systems and the like will stand or fall depending on the kinds of answers that brain research eventually reveals It all comes together in the brain
In brief recent conceptual developments in mind-brain science are seen to bring changes in worldview perspective that revise the ultimate criteria and frame of reference for determining human value priorities and resolving value differerence
R W Sperry Changing Priorities AnnRevNeursci1981
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
Artificial intelligence and advanced robotics have the potential to transform the world economy Changes are being made already especially in technology that acts like the human brain learning to complete more varied and complex tasks based on past experience The implications of this advancing technology in various facets of geopolitics are many from logistics labor and manufacturing to agriculture service and transportation mdash basically life in general
Artificial Intelligence Gets a Little Smarter Stratfor 18 03 2016
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
A brilliant new scientific landscape
that will reshape human destiny is
now trully opening up We are now
entering a new golden age of
neuroscienceConsciuosness is just another state
of matter like a solid liquid or gas
The 28 st RSF Conf
We are now entering a new golden
age of knowledge
Max Tegmark Solid Liquid Consciousness New Scientist 2014
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
In concluziehellip
De la culegător de gene
la
culegator de meme
Lipsa de identitate
cauza principala a CRIZEI
