Inpharma 1623 - 2 Feb 2008

■ Cranberry juice appears to be efficacious for theprevention of urinary tract infections (UTIs), but onlyin certain patient subpopulations, according to theresults of a Cochrane review and systematic meta-analysis. Data were assessed from ten randomisedcontrolled trials (total participants 1049) evaluating≥ 1 months’ treatment with cranberry juice or anothercranberry product. Meta-analyses found that cranberryproducts were associated with a significant reductionin the incidence of UTIs, compared with control,overall at 12 months (four trials; RR 0.66; 95% CI0.47, 0.92), and among participants with a history ofUTIs (two trials; 0.61; 0.40, 0.91). However, therewere no such benefits observed among elderlypatients or those requiring catheterisation.Jepson RG, et al. Cranberries for preventing urinary tract infections (review).Cochrane Database of Systematic Reviews : [22 pages], No. 1, 23 Jan 2008.Available from: URL: http://www.thecochranelibrary.com 801020198

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Inpharma 2 Feb 2008 No. 16231173-8324/10/1623-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved