Course - UMDNJpleiad.umdnj.edu/pathology_course/coursebk_02.doc · Web viewCourse in Pathology andLaboratory Medicine COURSE BOOK 2002 - 2003 Department of Pathology and Laboratory

Course in

Pathology andLaboratory Medicine

COURSE BOOK 2002 - 2003

Department ofPathology and Laboratory

Medicine

Robert Wood Johnson Medical School&

Robert Wood Johnson University Hospital

in collaboration with Pathology Facultyfrom the following Medical Centers

Jersey ShoreJ.F. KennedyMuhlenbergRaritan BaySomersetSt. Peter’s

VA at East Orange

University of Medicine and Dentistry of New Jersey

TABLE OF CONTENTS

Page

1. Teaching Personnel........................................ 1

2. Course Objectives.......................................... 2

3. Course Format................................................ 3

4. Course Requirements..................................... 6

5. Grade Appeal Mechanism.............................. 8

6. InstructionsHow to Approach the Textbook.................. 11Computer Education Program.................... 12Instructions for Computer Use.................... 13Strategies for Using Computers

in Self-learning................................ 14 PathTalk Sessions...................................... 15Case Based Study Sessions...................... 16Journal Club and Epi/Bio

Consultations.................................. 18

7. Examination Schedule.................................... 19

8. Pathology Course Highlights........................... 19

9. Teaching ScheduleFall Semester.............................................. 20Spring Semester......................................... 33

10. Summary of Weekly Reading Assignments.... 41

11. Summary of Case Study Assignments............ 43

12. Summary of Weekly Journal Club Articles...... 45

TEACHING PERSONNELPATHOLOGY DEPARTMENT CHAIRMAN

Dr. Peter AmentaCOURSE DIRECTOR COURSE

COORDINATORDr. David Weissmann Mrs.

Margee ChapinTeaching Office, 732-235-4033

COMPUTER EDUCATION Dr. David Foran, Director 235-4858

PATHTALK AND CASE BASED STUDY SMALL GROUPS GROUP PATHTALK INSTRUCTORS CASE BASED STUDY FACILITATORS

C1 Dr. Dr. Arnold Rabson Dr. Hong Ling WangC2 Dr. Tetsuo Shimamura Dr. Nirmala BathejaC3 Dr. Robert Trelstad Dr. Basim MohammedC4 Dr. Ady Kendler Dr. Janice

JohnsonC5 Dr. Gratian Salaru Dr. Parisa JavidianC6 Dr. Deepti Dhall Dr. Evan CadoffC207 Dr. Frederick Stone Dr. Eugene MartinC208 Dr. Douglas Charney Dr. David Weissmann

PART TIME INSTRUCTORSDr. Peter Amenta Dr. Anthony D’Aguillo Dr. Zaida Olmo-DurhamDr. Rene Artymyshyn Dr. Thomas Desmond Dr. Karel RaskaDr. Jin Choe Dr. Brian Erler Dr.

Brian Stanford

SUMMARY PRESENTATIONS/GROSS PRESENTATIONS Dr. Peter Amenta Dr. Parisa Javidian Dr. Tetsuo

Shimamura Dr. Nicola Barnard Dr. Hae Sook Kim Dr. Brian

Stanford Dr. Anthony D’Aguillo Dr. Faruk Presswalla Dr. Frederick

Stone Dr. Brian Erler Dr. Anrik Sahota

Dr. Robert Trelstad Dr. Ady Kendler Dr. Susan Shen-Schwarz Dr.

Peter Yurchenco

GUEST LECTURERSU.S. HEALTH CARE LANDSCAPE

Mr. Harvey Holzberg, President and CEO, Robert Wood Johnson University HospitalPATHOLOGY OF ORAL CAVITY AND RELATED STRUCTURES

Dr. Arnold Rosenheck, Asst. Dean of Hospital Affairs, New Jersey Dental School

CONSULTANTSEDUCATIONAL LIBRARY

Dr. Norma Saks 235-4129 Mrs. Zana Etter 235-4460 Dr. Robert LeBeau 235-4129

Dr. Grace Lee 235-4129

COMPUTER EDUCATION ADVISOR EPIDEMIOLOGY/BIOSTATISTICSDr. Robert Trelstad DEPT. OF ENVIRONMENTAL AND COMMUNITY MEDICINE 235-9525 Dr. Ronald Cody, Co-ordinator

235-4490 Dr. Daniel Wartenberg, Co-ordinator 445-

0197

OTHER PARTICIPATING FACULTY

Members of the Departments of Pathology and Medicine of affiliated hospitals

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COURSE OBJECTIVES

Pathology is the study of disease. The Course in Pathology and Laboratory Medicine provides an introduction to the mechanisms of disease and to the morphology and clinical characteristics of a broad spectrum of disease entities. In the Course we will aim to provide a foundation for the understanding of the disease state at the molecular, cellular, tissue, organ, and organismal levels.

By the end of the course, we expect that you will have:

1. Sufficient data about basic disease reactions and organ specific reactions so that you can:

a. interpret signs and symptoms elicited in a patient’s history and create a differential diagnosis;

b. interpret laboratory data;c. anticipate the natural course of disease;d. continue to learn the pathophysiology of disease;e. understand possible avenues of medical or surgical therapy.

2. Sufficient knowledge of gross pathology and histopathology so that you can:

a. interpret findings at surgery;b. interpret pathology reports;c. intelligently review pathology slides with a consulting pathologist.

3. A basic understanding of diagnostic laboratory evaluation and of the relationship between laboratory and morphological changes in diseases states.

4. An awareness of the role of the autopsy in medicine.

In addition, we expect that the unique format of this course will enable you:

- to develop skills in self-directed learning, problem solving, critical reasoning, presenting data, and intellectual team work;

- to relate basic science knowledge to clinical medicine;- to read and assess with critical intelligence the current medical literature

to facilitate life-long learning.

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COURSE FORMAT

THE COURSE IN PATHOLOGY AND LABORATORY MEDICINE covers:

GENERAL PATHOLOGY: The emphasis is on illustrating the basic reactions to disturbances which occur in the body.

SYSTEMIC PATHOLOGY: Deals with diseases specific to particular organs or systems.

LABORATORY MEDICINE: Throughout the course we introduce and integrate laboratory data which are frequently used in clinical medicine.

* * * * * * * * * * * * * * * * * * * *

The Course is based on small group instruction combined with a strong emphasis on independent learning, using a variety of learning resources and promoting the use of interactive computer programs. Also important are summaries in lecture format that highlight important concepts and facts in each major topic. The course program includes:

PathTalk Sessions: These small group sessions are designed to establish a close mentor relationship between students and faculty members and are mandatory. A typical session consists of a review of morphology and pathophysiology, including a question and answer period, and of the Journal Club (most of you will have the opportunity to present a relevant recently published article to the rest of the group). You are expected to come prepared for PathTalk, since the format of the session is a guided discussion, and everyone should participate. For additional information, see page 15.

Case Based Study (CBS) Sessions: This type of small group exercise consists of the study of clinical cases with the following main objectives: - to introduce basic laboratory evaluations reflecting the abnormal state, and - to promote the understanding of relationships between pathophysiology and morphological changes in disease states.Attendance at these sessions is mandatory, and you are expected to come prepared with written responses to questions. For additional information, see page 16.

Summaries of Topics in Systemic Pathology: emphasizing the main points that are important for their own sake and for examinations. Your attendance is required (see schedule).

Epidemiology/Biostatistics Consultations: These are informal sessions, given for almost all topics, designed to assist students with the evaluation of the statistical and epidemiological aspects of assigned Journal Club articles. Faculty members of the Department of Environmental and Community Medicine will conduct these sessions.

Gross Specimen Presentations: This exercise provides direct experience with the pathology of organs and tissues removed at surgery or at autopsy. All

specimens will be presented by instructors via closed circuit video. These specimens will be displayed in the laboratory following the video presentation, time permitting. The video will then be available in the Media Library for your use.

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Examinations: There will be three examinations throughout the Course. Two of these will be based on theoretical and practical multiple choice questions provided by faculty members. The third, final examination will be the Pathology section of Step I of the USMLE. NOTE: The time allotment assigned for an examination is not necessarily the actual length of time for the exam. A make-up examination, applicable only to eligible students with a grade of FAIL, will consist of questions provided by our faculty members.

STUDY MATERIAL

We realize that, in this age of an exponential increase in biomedical knowledge, we can provide only a limited coverage of our field. It is vital for every future physician to assimilate and update a large amount of information. Our course can offer only some dimensions of this process. It is important that you independently pursue every means available to gain continuing mastery of the subject. Throughout the Course we are allowing for unscheduled time to enable you to do so.

Required Reading: the textbook by Cotran, Kumar, and Collins, entitled Robbins’ PATHOLOGIC BASIS OF DISEASE (6th edition). You will enjoy both the text and the illustrations. Your “Required Reading” assignments are all from this Text and are listed in each week of the Teaching Schedule and in a Summary on page 39. The “Pocket Edition” of Robbins can be used by students for reviewing purposes only. For the most recent developments in the field, you should regularly consult the New England Journal of Medicine.

Required Material for Case Based Sessions: - LABORATORY MEDICINE CASE BOOK by Raskova, Shea, Skvara, and Mikhail (Appleton & Lange)

OR- LABORATORY MEDICINE CASE SET by Skvara, Mikhail, Shea, and Raskova (CD ROM, Keyboard Publishing, MedTech USA) -- Also available on all RWJ computer stations- LAB MEDICINE SERIES by Skvara, Mikhail, Shea, and Raskova (CD ROM, MedTech USA) -- Available in the Media Library

AND- PRINTED CASES provided in your weekly handouts

ALSO- The texbook entitled, CLINICAL LABORATORY MEDICINE (6th Edition), by Richard Ravel (Mosby)

Recommended Reading Texts are: - MANUAL OF LABORATORY AND DIAGNOSTIC TESTS, by Fischbach (Lippincott) - INTERPRETATION OF DIAGNOSTIC TESTS, by Wallach (Little Brown) (These will be most helpful in connection with the clinical cases discussed in CBS.) - THE MERCK MANUAL (16th Edition) - one of the TEXTBOOKS OF INTERNAL MEDICINE (Cecil’s or Harrison’s) - PATHOLOGY SECRETS, by Ivan Damjanov, M.D., Ph.D. (Hanley and Belfus)

Required Material for PathTalk Sessions: - SLIDE COLLECTION (arranged by weekly topics) - Media Library- SLIDE MANUAL - contains slide descriptions and other selected material

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Self-evaluation Material: we recommend the following:

- the TEXT entitled: PATHOLOGIC BASIS OF DISEASE, SELF-ASSESSMENT AND REVIEW by Carolyn C. Compton. Several copies are available in the Media Library.

- the TEXT entitled: Robbins REVIEW OF PATHOLOGY by Edward C. Klatt, M.D., and Vinay Kumar, M.D. Several copies are available in the Media Library.

- WEB BASED QUIZZES: (http://pleiad.umdnj.edu/)Pathology and Laboratory Medicine QuizImage-based Mini-quiz

Computer-based Learning Material: “KEYBOARD SERIES:” (installed on Interlab Computers) a computer program which permits the flexible use of texts, diagrams, questions.

- TEXTS: PATHOLOGIC BASIS OF DISEASE, by Cotran, Kumar, & Robbins (Pathology TextStacks) LABORATORY MEDICINE, by McClatchey (Laboratory Medicine TextStacks)

THE MERCK MANUAL (Merck Manual Textstacks)

- CASES: LABORATORY MEDICINE ”CaseSet” by Skvara, Mikhail, Shea, and Raskova

(Also see under Required Case Based Material)

“LAB MEDICINE SERIES:” by Skvara, Mikhail, Shea, and Raskova (CD ROM, MedTech USA) - available in the Media Library

Other Visual and Audiovisual Material: PROJECTION SLIDES: (Also see under Required Material for PathTalk Sessions.) Carousels labeled by subject and weekly topic are located in the Media Library. These are a part of your weekly assignments for the PathTalk small group sessions, and you are expected to review them prior to the session. Descriptions of slides in your Slide Manual. (Please bring it with you when you view slides.)

PHOTOGRAPHIC EXHIBITS of relevant findings for your Case Based Study small group sessions are displayed in the Media Library. These change on a weekly basis. You are expected to review them prior to the session.

VIDEO TAPES of Gross Specimen Presentations for this semester, as well as tapes recorded in recent years, are stored in the Media Library.

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REQUIREMENTS FOR THE SATISFACTORY COMPLETION OF THE COURSE

On the basis of examination results, the student will be awarded grades of Honors (4), High Pass (3), Pass (2), Low Pass (1), or Fail (0). In addition every student must satisfactorily perform in PathTalk sessions and Case Based Study sessions and attend the Summary Sessions. These performances will be reflected in the final written evaluation of each student, which will be submitted to the Registrar and to the Dean’s Office.

1. EXAMINATIONS

To pass the course a student must obtain a mean grade of sixty-five percent (65%) in the three examinations. Two of these examinations are based on questions selected by the Department; the third (final) examination is a Pathology section of Step I, USMLE. The results of this examination will be reported to you as a percentage grade. Each of the three examinations will carry equal weight. The final course grade awarded will be determined by the faculty and will depend on the mean examination percentage grade, provided attendance is adequate:

Mean Examination Final Course Percentage Grade Grade

0 - 64 0 (Fail) 65-68 1 (Low Pass) 69-78 2 (Pass) 79-82 3 (High Pass) 83-100 4 (Honors)

A student who receives a grade of FAIL can correct this grade to LOW PASS by passing a make-up examination, which will be composed and graded by the Department of Pathology and Laboratory Medicine. On this examination a student must achieve a score of at least sixty-five percent (65%).

2. PERFORMANCE IN PATHTALK SESSIONS

Each student must attend and meaningfully contribute to the PathTalk sessions. Each student will be required to:

- participate in group discussions;- evaluate morphological findings.

In addition, most students will have the opportunity to present a published article to his peers (Journal Club).

Student’s contributions will be evaluated by individual instructors.

3. PERFORMANCE IN CASE BASED STUDY SESSIONS

Each student must attend the Case Based Study sessions. Students will be evaluated by the individual instructors on their ability:

- to analyze problems;

- to provide both written and oral answers and interpretations to questions related to assigned cases;- to participate in group discussions

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4. ABSENCES/PERFORMANCE IN SMALL GROUPS

An unsatisfactory performance, as determined by your small group instructors, and/or more than a total of two (2) absences from each of your small group sessions will require remedial activity on an individual basis.

5. EVALUATIONS

The combined evaluations of PathTalk and CBS sessions will become the basis of the final written evaluation of each student by the Department.

At the end of the course, students will be evaluated on their performance, focusing on:

Case Based StudiesPathTalk

- general knowledge of material - general knowledge of material

- general interaction and participation in discussions - general interaction and participation in

discussions- performance as a moderator -

interpretative skills in histopathology

- ability to analyze cases/answer assigned questions - Journal Club presentation (in most

cases)

Students will also be evaluated in both groups on the non-cognitive attributes, such as:- commitment and general attitude- conscientiousness- collaboration with peers- leadership qualities- respect for other opinions- self-criticism- ethical behavior- honesty and integrity

The evaluation will be in the form of a short paragraph, to be included in student’s transcript. Each student will have the opportunity to review the evaluation before it is submitted.

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GRADE APPEAL MECHANISMThe Course in Pathology and Laboratory Medicine allows for and strongly encourages student-faculty interaction. We believe that good communication between student and teacher is important for mutual understanding and that it is essential for learning.

EXAMINATION GRADE: After each departmental examination you will receive a preliminary examination grade on that examination. The examination booklets, a copy of the master key, and a copy of your answer sheet will be returned to you, and you are given a period of three to five days for review and discussion of the examination before a final examination grade is determined. During this time you should contact the Course Director with problems, comments, etc. Any adjustment in the examination will be made by the Course Director and will apply to the whole class. The class will be notified of it, as well as of the reasons justifying the adjustment. NO ADDITIONAL CHANGES ARE MADE AFTER THE FINAL GRADE ON EACH DEPARTMENTAL EXAMINATION IS ISSUED.

The USMLE Pathology section Step 1 Examination is exempt from the above procedure. The grade you receive on this examination is not subject to discussion.

EVALUATION OF SMALL GROUP PERFORMANCE (PATHTALK AND CASE BASED STUDIES): You will be given a copy of your course evaluation, which is based on your performance in small groups. If a serious discrepancy occurs between a student’s perception of his/her performance in the course and the evaluation, the student should appeal in writing to the Course Director, and the case will be reexamined.

FINAL COURSE GRADE: This grade is determined entirely on the basis of examination results, provided attendance is adequate. No adjustment can be made after the grade is awarded.

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I N S T R U C T I O N S

HOW TO APPROACH THE TEXTBOOK

MEDICAL EDUCATION INITIATIVES IN PATHOLOGY

INSTRUCTIONS FOR COMPUTER USE

STRATEGIES FOR USING COMPUTERS IN SELF-LEARNING

PATHTALK

CASE BASED STUDY

JOURNAL CLUB AND EPI/BIO CONSULTATIONS

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TEXTBOOK

Norma S. Saks, Ed.D

The textbook that has been selected for this course, Pathologic Basis of Disease, 6th Edition (Cotran, Kumar, and Collins) is an essential resource for your independent study. Because the text is comprehensive and detailed, reading effectively and efficiently will be helpful. An additional handout, Strategies for Studying Pathology, can be obtained at the Cognitive Skills Program offices, UBHC, D338.

How to Approach the Pathology Textbook for Effective Independent Study

Engage in an active (vs. Passive) approach to reading as follows:

1. Develop the habit of looking at the whole chapter/section first to see how it is organized. If you know the structure of the material (“the big picture”), it will help you recall it better; it promotes a “cognitive framework” to which you can pin details.

2. Attend to the format of the textbook - Main headings, subheadings, color coding, diagrams, charts, photographs, general physical arrangement. Think about how the format can aid your learning.

3. Some students like to focus study by reading related questions.

4. Read for a purpose and adjust your rate to that purpose. If you come across material that you already know, then read through it quickly. If your purpose is to learn/understand, then slow down your rate. It is most effective to develop advance questions and then go on a “search” to find answers to your questions.

5. When you identify unfamiliar vocabulary, note the word(s) and follow up. If the meaning of a word is essential in order to make sense of what you are reading, look it up immediately. (It is best to have a medical dictionary and your Webster’s nearby.) Keep in mind that these same words may appear on an exam later on.

6. Look for relationships, not just a collection of facts. Compare and contrast. This method will aid in your retention of the material.

7. Develop a notetaking system. How will you remember without rereading the text? Decide on a format and how much detail you will include.

8. Assess your comprehension at frequent intervals. Summarize after a meaningful chunk. Paraphrase (restate in your own words).

9. Assess your concentration at frequent intervals. Stay alert. Avoid reading the text as if it were a novel.

10. Assess your need for additional resources and use these as needed. It is best not to give up on reading the text.

* For individual consultation about effective and efficient reading/learning, please call the Cognitive Skills Program offices at 732-235-4129 (Dr. Grace Lee, Ed.M.; Dr. Robert Lebeau, Ed.D.; Dr. Norma Saks, Ed.D.).

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COMPUTER EDUCATION PROGRAMDavid Foran, Ph.D.

We first wish to extend a warm welcome to each of you. In order to facilitate your mastery of the subject material the faculty are developing a number of interactive exercises for web-based teaching in pathology. While several of the projects are in the early stages of development, the first two web-based tools are now accessible through the Departmental web server at http://pleiad.umdnj.edu/. Once connected to the server you should click on “2nd Year Course in Pathology & Lab Medicine.” You will then be presented with options to engage in an interactive Review of Pathology and Laboratory Medicine or to take an Image-based Mini-Quiz in Pathology.

If you choose the first option, “Review: Pathology & Lab Medicine” you may choose from approximately 26 broad topics. You will subsequently be prompted for your full name. You will be presented with questions which relate to the topic of interest. The program features immediate feedback regarding the answers that you submit as well as a total score for the section. Once the exercises for any given session are completed, the total score and correct answers are displayed. The web-based review also features a random mode, with questions selected at random across all topics. While an extensive “Image-based Quiz” is currently being developed, you might like to have a look at the “Image-based Mini-Quiz,” based on 24 questions.

You may also access this material by connecting directly to the Pathology and Laboratory Medicine Course Website http://pleiad.umdnj.edu/pathology_course/.

We hope that you will enjoy 2nd year course in Pathology & Laboratory Medicine, and we welcome your comments. For comments please contact:

David J. Foran, Ph.D. 732-235- 4858David Weissmann, M.D. 732-418-8047Margee Chapin 732-235-4033

Wei He 732-235-5680

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PATHOLOGY AND LABORATORY MEDICINEROBERT L. TRELSTAD, MD

The facilities for computer assisted education are distributed throughout the Kessler Teaching Labs.

The SOFTWARE available for all medical students includes, but is not limited to:

Textbooks, with figures, diagrams, tables, and references of:

* Pathologic Basis of Disease by Cotran, Kumar, and RobbinsW.B. Saunders

* Clinical Laboratory Medicine by Ken McClatcheyWilliams and Wilkins

* Medical Microbiology edited by Ken RyanAppleton & Lange

* Immunology by Ivan RoittBlackwell Science

* The Merck Manual edited by Robert BerkowMerck

Cases:

* Laboratory Medicine “Case Set”by Skvara, Mikhail, Shea, and Raskova

* Lab Medicine Seriesby Skvara, Mikhail, Shea, and Raskova

Quizzes:

* Laboratory Medicine “Case Set”by Skvara, Mikhail, Shea, and Raskova

* Pathology* Microbiology* Cell Biology* Immunology

Videodisc Image Libraries:

* Histology* Pathology

* Microbiology

Digital Image Libraries:

* Histology* Pathology

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STRATEGIES FOR USING COMPUTERS IN SELF-LEARNINGROBERT L. TRELSTAD, MD

The computer resources you have at your disposal are extensive and match or exceed those of most medical schools. Like any new tool, the value of the computer in education is undergoing rapid change.

Computers will never replace print books. You can drop your book, take it to the beach, or sit on it. It never runs out of energy; you do.

Computer based textbooks can be searched very rapidly. Using the Keyboard Publishing, Inc., platform, all of the textbooks, quizzes, and image banks can be searched simultaneously. You should learn to use the search function of this software so that you can read in topics beyond your immediate target. For example, if you search for endocarditis in Robbins, Sherris, and Merck, you’ll get very comprehensive treatment of the subject. If you construct your searches with some restrictions, such as ‘endocarditis’ and ‘strepto*’, where the ‘*’ allows finding of all words starting with strepto, you can limit the results of the search. If you further limit the finding of these words to within 10 to 15 words of each other, you further reduce and focus the information you’ll get.

We have discontinued our “how to use the computer” sessions in that most students not only know how, but own them. If you feel that you aren’t using the computer effectively, please ask for help. Channel your requests through the Teaching Office. At various times during the course, we will give you demonstrations in which we will use the computer resources.

In addition to the local set of software, there is an extensive amount of material available on the Internet. The ‘net’ is moving from CB radio to AM. It is filled with junk and great stuff. So what’s new? Ever been to WalMart? The following are web sites we suggest you explore.

http://pleiad.umdnj.edu/Our department’s web site. Images, quizzes, and information.

http://pleiad.umdnj.edu/pathology_course/Our Pathology and Laboratory Medicine Course web site.

www-medlib.med.utah.edu/WebPath/webpath.htmlThe premier pathology education web sites. Quizzes, images,

information.

www.pathmax.com/main.htmlA wonderful collection of every kind of internet pathology resource.

http://pleiad.umdnj.edu/hemepathA lymphoma tutorial.

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PATHTALK SESSIONS

OBJECTIVE

- To review morphology and pathophysiology of the assigned topic and to monitor students' understanding and mastery of the subject.

FORMAT

This is an interactive small group session. It is necessary that you come prepared, since your participation is expected.

- You will discuss basic facts and concepts of the assigned topic. You should be ready both to ask and to answer questions related to the topic.

- You should be familiar with assigned images of gross and microscopic lesions and be ready to interpret them.

- You will be asked to interpret some previously unassigned images ("unknown slides").

- Most of you will present a Journal Club article (see page 18), and you will monitor the discussion of your presentation. Unless otherwise noted, the selected articles are from the New England Journal of Medicine. They are listed in each week of the Teaching Schedule and in a Summary on page 45.

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CASE BASED STUDY SESSIONS

OBJECTIVE

- To introduce basic laboratory evaluation reflecting the abnormal state and to promote the understanding of relationship between laboratory and morphological changes in disease states

FORMAT

The format of CBS is intended to facilitate learning through active student particiption. Students are expected to study the material and conduct a discussion on the various aspects of the case and to arrive at a conclusion as to what ails the patient.

A. Role of the Instructor:

The principal role of the instructor should be that of a MODERATOR; the instructor is free to intervene in discussions and to supplement available information. These sessions should be, however, predominantly student driven. The role of the instructor is to encourage the student “in charge” to elicit more discussion of the case, including a differential diagnosis based on findings. The instructor is not expected to provide answers to all questions raised, nor is the student who is “in charge” of the case. These should be answered through participation of the whole group. All students are expected to actively participate in the discussion. Every student should be given an opportunity to express an opinion and contribute to the resolution of the case.

B. Printed Cases:

Each week all students will have been assigned one to two printed cases. These will be a part of their handouts.

1. The students should study the case and provide a written summary of the diagnosis and conclusion from the case material.

2. On the day of the session, one student will be selected to be “in charge” of the case. This student should:

- review the Clinical Summary and prompt discussion of a differential diagnosis based on the demographics of the patient and clinical findings.

- call on other students to give the answer to questions at the end of each case; one student should be responsible for answering one question. The group should correct/supplement/support this student’s view. The instructor should make a final comment on each of these answers. The instructor should guide the group to cover the objectives that are relevant to the case (as stated each week in the Assignments and Objectives Guide) and to supplement those answers to questions that remained unanswered by the students during the discussion.

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CASE BASED STUDIES SESSIONS (continued):

- project slides pertaining to the case. (These slides will be provided at the beginning of each session.) There will be images previously available to students and images students have not seen prior to the session. The student “in charge” should call on other students for slide descriptions and comments. The instructor should correct/support students’ comments, discuss the types of diagnosis that the slide review indicates, and summarize all findings.

3. The instructor will provide closing comments with a brief discussion of how the findings and lab values support the final diagnosis.

4. The written case summary (students’ homework) will be collected and returned at the next session with instructor’s comments.

C. “Computer/Book” Cases:

Each week all students will have been assigned one to three cases from the Laboratory Medicine Case Book or Case Set. These cases also contain multiple choice questions (with complete answers) and images (with descriptions). For each of these cases one student will be selected (student “in charge”) to briefly review the case from the computer and to discuss with the group all pertinent points of the case.

This student should:

- summarize the case in his own words

- discuss with the group the objectives of the case (these are stated weekly in the Assignments and Objectives Guide)

- review the morphological findings in the case.

At the end of each case, the instructor will add a few additional relevant points for group discussion.

FOOTNOTE:

- Procedure for Accessing Computer Cases:

. Enter your code, etc.

. When you are in “Case Set,” click on “contents.”

. Click on “SOLVE CASE.”

. Select the assigned case.

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JOURNAL CLUB GUIDELINESprepared by

Stephen M. Shea, M.D.

Medical knowledge is changing fast. The best way for a physician to “keep up” is to keep searching and reading the literature. One must learn to read effectively and critically. This is where the Journal Club comes in: critical presentation of an article to a critical audience.

HOW TO PRESENT AN ARTICLE

The idea is to present the substance of a journal article to your colleagues critically and succinctly. It should not take more than fifteen minutes. To get your bearings, after reading the article’s title, read the abstract, especially its punchline, to see what the authors claim to show.

In journals like the New England Journal of Medicine, articles are often multi-authored, but in general fall into one of two categories - reports from a single department (e.g. Medicine) on observations based on a limited patient population, or large multi-center studies.

When you describe methods to your fellows, you need not go into great detail, especially in the case of multi-center studies or review articles, which you may have to present in skeleton form.

Present the findings: usually you will find them nicely tabulated.

Present the discussion: here you can afford to be critical. Were the right controls used: are the statistical arguments convincing? Give your opinion, and ask your colleagues for theirs.

It may seem hard, but it is much more effective to make do without consulting notes. The effort to do so forces one to digest the material and discard the dross. If you say it in your “own words,” you will find you understand matters in a new way, and your audience will understand better, too. You can also make effective use of the blackboard in this way; don’t fill it up in advance, but write down salient points “on the fly.”

The audience should be invited to ask questions, and they should do so. Everyone should become involved.

When the club functions this way, all gain, especially in becoming unselfconscious and effective in thinking on their feet, in clarifying their thoughts, and expressing them effectively.

WHEN TO SEEK EPI/BIO CONSULTATION

Many of the articles will involve quantitative data, often with epidemiological features. It is important that you learn to interpret these; not all published conclusions are necessarily correct. We strongly encourage you to take advantage of the Epi/Bio consultation program, offered by the faculty of the Department of

Environmental and Community Medicine to our students, on Mondays. See the schedule for time and location.

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2002 - 2003COURSE IN PATHOLOGY AND LABORATORY

MEDICINE

TEACHING SCHEDULE

FALL SEMESTERSPRING SEMESTER

August 12 - December 13, 2002 January 13 - May 5, 2003

PATHOLOGY EXAMINATION SCHEDULE

Exam #1 Friday, October 4, 20029:00 AM

Exam #2 Friday, February 7, 20039:30 AM

Final Exam Monday, May 5, 20039:30

AM

HIGHLIGHTS

Guest Lecture: Mr. Harvey Holzberg, President and CEO, Tuesday, 8/13/02

Robert Wood Johnson University Hospital 1:00 PM

TOPIC: U.S. Health Care Landscape

Guest Lecture: Dr. Arnold Rosenheck, Asst. Dean of Hospital Affairs, Monday,

1/27/03 New Jersey Dental School

1:30 PM

TOPIC: Pathology of Oral Cavity and Related Structures

Dr. Nagy Mikhail: Introduction to the AutopsyTuesday,

8/27/02 1:00 PM

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FALL SEMESTER_________________________________________________________________________________ WEEK 1

August 12 - 16, 2002

_________________________________________________________________________________

FOCUS CELL AND TISSUE REACTIONS TO INJURYENVIRONMENTAL PATHOLOGY

READING ASSIGNMENT: Chapter 1, pp. 1-28 Chapter 10, pp. 403-436 Chapter 2, pp. 31-48 Chapter 16, pp. 727-734

CASE ASSIGNMENTS: Laboratory Medicine Case Book (for Case Based Study) Chapter 15

ORLaboratory Medicine Case Set CD ROM

Chapter 20Printed Case #1/1

MONDAY, August 12

9:00 AM - Noon Pathology Course Orientation

Lecture Hall

TUESDAY. August 13

1:00 PM - 2:00 PM Guest Lecture: Mr. Harvey Holzberg

Lecture Hall U.S. Healthcare Landscape2:00 PM - 4:00 PM CASE BASED STUDY Laboratory

THURSDAY, August 15

1:00 PM - 4:00 PM PATHTALK Laboratory

FRIDAY, August 16

10:00 AM - 11:00 AM Summary: Dr. Trelstad Lecture Hall11:00 AM - Noon Consultations Lecture Hall Journal Club-Epi/Bio Consultation

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FALL SEMESTER____________________________________________________________________________________ WEEK 2 Note Schedule Change for PathTalk

August 19 - 23, 2002____________________________________________________________________________________

FOCUS INFLAMMATION/TISSUE REPAIR/CIRCULATORY FACTORS IN INJURY

READING ASSIGNMENT: Chapter 3, pp. 50-87Chapter 4, pp. 89-111Chapter 5, pp. 113-137

CASE ASSIGNMENTS: Laboratory Medicine Case Book (for Case Based Study) Chapters 14, 19


Chapters 19, 24Printed Case #2/1

JOURNAL CLUB ARTICLE: PathTalk: Chimerism of the Transplanted Heart/ Regeneration of the Human Heart - No Chimera?/ Can

the Heart Repair Itself? Vol.346, #1, p.5/p.55/p.2.

TUESDAY, August 20

1:00 PM - 3:00 PM CASE BASED STUDY Laboratory3:00 PM - 4:00 PM Independent Study

THURSDAY, August 22


FRIDAY, August 2310:00 AM - 11:00 AM Summary: Dr. Yurchenco Lecture Hall11:00 AM - 12:00 AM Consultations Lecture Hall

Journal Clu

b-Epi/Bio Consultation

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FALL SEMESTER____________________________________________________________________________________ WEEK 3 August 26 - 30, 2002____________________________________________________________________________________

FOCUS DISEASES OF IMMUNITY/ONCOGENESIS/NEOPLASIA

READING ASSIGNMENT: Chapter 7, pp. 216-257 (pp. 188-216 for Review)Chapter 16, pp. 712-716Chapter 27, pp. 1201-1205Chapter 8, pp. 260-276; 319-325(pp. 276-319 for Review)




JOURNAL CLUB ARTICLE: PathTalk: Comparison of Four Chemotherapy Regimens for Advanced Non-small-cell Lung Cancer/Lung Cancer - Time to Move on From Chemotherapy. Vol.346, #2, p.92/p.126.

TUESDAY. August 27

1:00 PM - 2:00 PM Introduction to the Autopsy: Dr. Mikhail

Lecture Hall2:00 PM - 4:00 PM CASE BASED STUDY Laboratory

THURSDAY, August 29


FRIDAY, August 30

10:00 AM - 11:00 AM Summary: Dr. Presswalla Lecture Hall

Discussion on Forensic Medicine

11:00 AM - NOON Consultations

Lecture Hall Journal Club-Epi/Bio Consultation

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FALL SEMESTER____________________________________________________________________________________ WEEK 4 September 2 - 6, 2002____________________________________________________________________________________

FOCUS GENETICS

READING ASSIGNMENT: Chapter 6, pp. 139-187



Chapter 17 Printed Case #4/1

JOURNAL CLUB ARTICLES: PathTalk: A Deletion Involving the Connexin 30 Gene in Nonsyndromic Hearing Impairment. Vol.346, #4, p.243.

TUESDAY. September 3


THURSDAY, September 5


FRIDAY, September 6

10:00 AM - 11:00 AM Summary: Dr. Sahota Lecture Hall11:00 AM - NOON Consultations Lecture Hall Journal Club-Epi/Bio Consultation

-23-FALL SEMESTER

____________________________________________________________________________________ WEEK 5 September 9 - 13, 2002____________________________________________________________________________________

FOCUS DEVELOPMENTAL PATHOLOGY/ PERINATAL AND PEDIATRICS

READING ASSIGNMENT: Chapter 11, pp. 459-489Chapter 24, pp. 1079-1089HANDOUT: Developmental Anomalies



Chapter 37Printed Case #5/1

JOURNAL CLUB ARTICLES: PathTalk: Birth Defects and In Vitro Fertilization/ Infertility. Vol.346, #10, p.725/p.769.





FRIDAY, September 13

10:00 AM - 11:00 AM Summary: Dr. Shen-Schwarz Lecture Hall11:00 AM - NOON Consultations Lecture Hall Journal Club-Epi/Bio Consultation

-24-

FALL SEMESTER____________________________________________________________________________________ WEEK 6 Note Schedule Change For PathTalk September 16 - 20, 2002____________________________________________________________________________________

FOCUS HEMATOPOIETIC SYSTEM/LYMPH NODES AND SPLEEN

READING ASSIGNMENT: Chapter 15, pp. 645-675; 688-693(pp. 675-688 for Review)(Chapter 14, pp.601-642 for Review)




JOURNAL CLUB ARTICLE: PathTalk: Long-Term Prognosis in Monoclonal Gammopathy of Undetermined Significance.

Vol.346, #8, p.564.





FRIDAY, September 20

11:00 AM - NOON Summary: Dr. Stanford Lecture Hall

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FALL SEMESTER____________________________________________________________________________________ WEEK 7

September 23 - 27, 2002

____________________________________________________________________________________

FOCUS INDEPENDENT STUDY


1:00 PM - 4:00 PM Independent Study


9:00 AM - NOON Independent Study

____________________________________________________________________________________ WEEK 8

September 30 - October 4, 2002

____________________________________________________________________________________

FOCUS EXAMINATION

Friday, October 4

9:00 AM - NOON FIRST EXAMINATION IN PATHOLOGY

East and West Lecture Halls

Note: Although the time frame for the exam is 3 hours, the actual time allotted for your taking the exam will be less than that.

-26-

FALL SEMESTER____________________________________________________________________________________ WEEK 9 NOTE: Schedule Changes From Previous Weeks October 7 - 11, 2002 ____________________________________________________________________________________

FOCUS THE CARDIOVASCULAR SYSTEM

READING ASSIGNMENT: Chapter 12, pp. 493-540Chapter 13, pp. 543-598

CASE ASSIGNMENTS: Laboratory Medicine Case Book (for Case Based Study)

Chapters 7, 16OR

Laboratory Medicine Case Set CD ROMChapters 9, 21

Printed Case #9/1

JOURNAL CLUB ARTICLE: PathTalk: Antioxidants to Prevent Coronary Artery Disease/Antioxidant Therapy. Vol.345, #23, p.1583/p.1636..

MONDAY, October 7

11:00 AM - Noon Consultations Lecture Hall Journal Club -

Epi/Bio Consultations


WEDNESDAY, October 9


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FALL SEMESTER____________________________________________________________________________________ WEEK 10 October 14 - 18, 2002____________________________________________________________________________________

FOCUS THE CARDIOVASCULAR SYSTEM(Continued)

No Pathology Classes - Independent Study

____________________________________________________________________________________ WEEK 11 October 21 - 25, 2002____________________________________________________________________________________

FOCUS THE CARDIOVASCULAR SYSTEM(Continued)

FRIDAY, October 25

9:00 AM - 10:00 AM Gross Presentation: Dr. Amenta

Lecture Hall10:00 AM - 11:15 AM Summary: Dr. Amenta Lecture Hall11:15 AM - NOON Consultations Lecture Hall Journal Club-Epi/Bio Consultation

____________________________________________________________________________________ WEEK 12

October 28 - November 1, 2002____________________________________________________________________________________

NO ASSIGNMENT/NO PATHOLOGY CLASSES

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FALL SEMESTER____________________________________________________________________________________WEEK 13

November 4 - 8, 2002 ____________________________________________________________________________________

FOCUS KIDNEY/LOWER URINARY TRACT/MALE GENITAL TRACT

READING ASSIGNMENT: Chapter 21, pp. 930-995Chapter 22, pp. 997-1010Chapter 23, pp. 1011-1033Supplemental Material in “Assignments and

ObjectivesGuide”




JOURNAL CLUB ARTICLES: PathTalk: Urinary Tract Infections Caused by Multi-drug Resistant E. Coli/An Epidemic of Urinary Tract

Infections. Vol.345, #14, p.1007/p.1055.

MONDAY, November 4


WEDNESDAY, November 6


____________________________________________________________________________________WEEK 14

November 11 - 15, 2002 ____________________________________________________________________________________


(Continued)


-29-FALL SEMESTER

____________________________________________________________________________________WEEK 15

November 18 - 22, 2002 ____________________________________________________________________________________


(Continued)

MONDAY, November 18

1:00 PM - 2:00 PM Gross Presentation: Dr. D’Aguillo

Lecture Hall2:00 PM - 4:00 PM Summary: Dr. Shimamura Lecture Hall

(See Supplemental Reading)

____________________________________________________________________________________ WEEK 16

November 25 - 29, 2002____________________________________________________________________________________

NO ASSIGNMENT/NO PATHOLOGY CLASSES

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FALL SEMESTER____________________________________________________________________________________WEEK 17 December 2- 6, 2002 ____________________________________________________________________________________

FOCUS THE RESPIRATORY SYSTEM

READING ASSIGNMENT: Chapter 16, pp. 697-753(Chapter 11, pp. 471-473 for Review)




JOURNAL CLUB ARTICLE: PathTalk: Pulmonary Embolism and Air Travel/Air Travel and Venous Thromboembolism.

Vol.345, #11, p.779/p.828.

MONDAY, December 2

11:00 AM - Noon Consultations Lecture Hall Journal Club -

Epi/Bio Consultations1:00 PM - 3:00 PM CASE BASED STUDY Laboratory3:00 PM - 4:00 PM Independent Study

WEDNESDAY, December 4


____________________________________________________________________________________WEEK 18

December 9 - 13, 2002 ____________________________________________________________________________________

FOCUS THE RESPIRATORY SYSTEM(Continued)

THURSDAY, December 12

9:00 AM - 10:00 AM Gross Presentation: Dr. Kim

Lecture Hall10:00 AM - NOON Summary: Dr. Stone Lecture Hall

-31-FALL SEMESTER - SPRING SEMESTER

____________________________________________________________________________________WEEK 19

December 16, 2002 - January 10, 2003 WEEK 20WEEK 21 ____________________________________________________________________________________

NO ASSIGNMENTS/NO PATHOLOGY CLASSES

-32-

SPRING SEMESTER____________________________________________________________________________________WEEK 22 NOTE TIME CHANGES

January 13 - 17, 2003 ____________________________________________________________________________________

FOCUS GASTROINTESTINAL TRACT HEPATOBILIARY PATHOLOGY

NUTRITIONORAL CAVITY AND ASSOCIATED STRUCTURES

READING ASSIGNMENT: Chapter 18, pp. 775-842 Chapter 10, pp. 436-456

Chapter 19, pp. 845-900 Chapter 17, pp. 756-773

Chapter 20, pp. 902-913

JOURNAL CLUB ARTICLE No article this week.

CASE ASSIGNMENTS: Laboratory Medicine Case Book (for Case Based Study) Chapters 12,

18, 29 ORLaboratory Medicine Case Set CD ROM

Chapters 14, 23, 39Printed Case #22/1, #22/2

MONDAY, January 13


WEDNESDAY, January 15

1:30 PM - 2:30 PM Gross Presentation: Dr. D’Aguillo

Lecture Hall2:30 PM - 4:30 PM PATHTALK Laboratory

____________________________________________________________________________________WEEK 23

January 20 - 24, 2003 ____________________________________________________________________________________




-33-

SPRING SEMESTER____________________________________________________________________________________WEEK 24

January 27 - 31, 2003

____________________________________________________________________________________



MONDAY, January 27

1:30 PM - 3:00 PM Guest Lecture: Dr. Rosenheck

Lecture Hall Oral Cavity and Associated Structures

3:00 PM - 3:45 PM Summary: Dr. Amenta Lecture Hall3:45 PM - 4:30 Consultations Lecture Hall Journal Club - Epi-

Bio Consultations

____________________________________________________________________________________WEEK 25

February 3 - 7, 2003 ____________________________________________________________________________________

FOCUS EXAMINATION

Friday, February 7

9:30 AM - 12:30 PM SECOND EXAMINATION IN PATHOLOGY

East and West Lecture Halls

Note: Although the time frame for the exam is 3 hours, the actual time allotted for your taking the exam will be less than that.

-34-

SPRING SEMESTER____________________________________________________________________________________ WEEK 26 February 10 - 14, 2003____________________________________________________________________________________

FOCUS ENDOCRINE SYSTEM





JOURNAL CLUB ARTICLE: PathTalk: Diet, Life Style, and Type II Diabetes Mellitus in Women. Vol.345, #11, p.790.

MONDAY, February 10


WEDNESDAY. February 12


____________________________________________________________________________________ WEEK 27 February 17 - 21, 2003____________________________________________________________________________________

FOCUS ENDOCRINE SYSTEM(Continued)

MONDAY, February 17

1:30 PM - 3:00 PM Summary: Dr. Erler Lecture Hall3:00 PM - 4:00 PM Consultations Lecture Hall Journal Club - Epi/Bio

Consultations

-35-

SPRING SEMESTER____________________________________________________________________________________ WEEK 28

February 24 - 28, 2003____________________________________________________________________________________

FOCUS DISEASES OF THE SKINDISEASES OF BONE

READING ASSIGNMENT: Chapter 27, pp. 1170-1212Chapter 28, pp. 1215-1267Chapter 9, pp. 388-389



Chapters 27, 29Printed Cases: 1/1

JOURNAL CLUB ARTICLE: PathTalk: IV Zoledronic Acid in Postmenopausal Women With Low Bone Mineral Density/Bisphosphonates

and Osteoporosis. Vol.346, #9, p.653/p.642.

MONDAY, February 24


WEDNESDAY, February 26


FRIDAY, February 28

11:00 AM - NOON Summary (Bone): Dr. Javidian

Lecture HallNOON - 12:30 PM Consultations

Journal Club - Epi/Bio Consultations

-36-


March 3 - 21, 2003 WEEK 30WEEK 31 ____________________________________________________________________________________


____________________________________________________________________________________WEEK 32 Note Schedule Change This Week March 24 - 28, 2001____________________________________________________________________________________

FOCUS FEMALE GENITAL TRACT

READING ASSIGNMENT: Chapter 24, pp. 1035-1079(pp. 1079 - 1089 for Review)



Chapter 40Printed Cases #32/1

JOURNAL CLUB ARTICLES: PathTalk: Male Circumcision, Penile Human Papillomavirus Infection, and Cervical Carcinoma

in Female Partners/Cervical Carcinoma and the Elusive Male Factor. Vol.346, #15, p.1105/9.1160.

MONDAY, March 24


TUESDAY, March 25


FRIDAY, March 28

1:30 PM - 2:30 PM Summary: Dr. Barnard Lecture Hall2:30 PM - 3:30 PM Consultations

Lecture Hall Journal Club - Epi/Bio Consultations

-37-SPRING SEMESTER

____________________________________________________________________________________WEEK 33

March 31 - April 4, 2003

____________________________________________________________________________________

FOCUS DISEASES OF THE BREAST

READING ASSIGNMENT: Chapter 25, pp. 1093-1118(Chapter 8, pp. 260-325 for Review)

CASE ASSIGNMENTS: Laboratory Medicine Case Book (for Case Based Study)

Chapters 24OR

Laboratory Medicine Case Set CD ROMChapters 34

Printed Cases #33/1

JOURNAL CLUB ARTICLES: PathTalk: Breast Cancer After Prophylactic Bilateral Mastectomy in Women with BRCA1 or BRCA2 Mutation/Mastectomy for Women with

BRCA1/BRCA2. Vol.345, #3, p.159/p.207.

MONDAY, March 31


TUESDAY, April 1


FRIDAY, April 4

1:30 PM - 2:30 PM Summary: Dr. Barnard Lecture Hall2:30 PM - 3:30 PM Consultations Lecture Hall Journal Club -

Epi/Bio Consultations

-38-

SPRING SEMESTER____________________________________________________________________________________WEEK 34 April 7- 11, 2003 ____________________________________________________________________________________

FOCUS DISEASES OF MUSCLE/NEUROPATHOLOGY(Continued)





JOURNAL CLUB ARTICLE: PathTalk: Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest/Hypothermia to Protect the Brain/Therapeutic Hypothermia After Cardiac

Arrest. Vol.346, #8, p.549/p.546/p.612.

MONDAY, April 7


TUESDAY, April 8


____________________________________________________________________________________WEEK 35 April 14 - 18, 2003 ____________________________________________________________________________________

FOCUS DISEASES OF MUSCLE/NEUROPATHOLOGY

TUESDAY, April 15

10:00 AM - 11:30 AM Summary and Gross Presentation: Dr. Kendler

-39-


April 21 - May 2, 2003 WEEK 37____________________________________________________________________________________


____________________________________________________________________________________WEEK 38

May 5 - 9, 2003 ____________________________________________________________________________________

FOCUS EXAMINATION

Monday, May 5

9:30 AM - 12:30 PM FINAL EXAMINATION IN PATHOLOGY

East and West Lecture Halls (NBME Subject Exam)

Note: Although the time frame for the exam is 3 hours, the actual time allotted for your taking the exam will be less than that, as designated by the National Board of Medical Examiners.

C O N G R A T U L A T I O N S ! !

-40-

THE COURSE IN PATHOLOGY AND LABORATORY MEDICINE, 2002 - 2003 READING ASSIGNMENTS

TEXT: Robbins PATHOLOGIC BASIS OF DISEASE, 6th Edition

(SUBJECT TO CHANGE)

WEEK 1: Cell and Tissue Chapter 1, pp. 1-28 (Cellular Injury and Death) Reaction to Injury Chapter 2, pp. 31-48 (Cellular Growth and

Differentiation Environmental Chapter 10, pp. 403-436 (Environmental Path.) Pathology Chapter 16, pp. 727-734 (Environmental Path.)

WEEK 2: Inflammation/Tissue Chapter 3, pp. 50-87 (Inflammation) Repair/Circulatory Chapter 4, pp. 89-111 (Tissue Repair) Factors in Injury Chapter 5, pp. 113-337 (Hemodynamic Disorders,

Thrombosis, Shock)

WEEK 3: Immunity/Oncogenesis/ Chapter 7, pp. 216-257 (188-216 for Review) (Immunity) Neoplasia Chapter 16, pp. 712-716 (Asthma)

Chapter 27, pp. 1201-1205 (Blistering Diseases)Chapter 8, pp. 260-276; 319-325 (276-319 for Review)

(Neoplasia)

WEEK 4: Genetics Chapter 6, pp. 139-187

WEEK 5: Developmental Path./ Chapter 11, pp. 459-489 (Diseases of Infancy Perinatal and Pediatric and

Childhood) Path. Chapter 24, pp. 1079-1089 (Gestational and

Placental Disorders)Supplemental material titled, “Developmental Anomalies,”

in Assignments and Objectives Guide

WEEK 6: Hematopoietic System/ Chapter 15, pp. 645-675; 688-693 (675-688 for Review) Lymph Node, Spleen (Chapter 14, pp.601-642 for Review)

WEEKS 9, Cardiovascular System Chapter 12, pp. 493-540 (Blood Vessels) 10, 11: Chapter 13, pp. 543-598 (Heart)

WEEKS 13, 14, 15: Kidney Chapter 21, pp. 930-995 (Kidney) Lower Urinary Tract Chapter 22, pp. 997-1010 (Lower Urinary Tract)

Male Genital System Chapter 23, pp. 1011-1033 (Male Genital System)Supplemental material in Assignments and Objectives Guide

WEEKS 17, Respiratory System Chapter 16, pp. 697-753 (Lung) 18: (Chapter 11, pp. 471-473 for Review)

-41-

THE COURSE IN PATHOLOGY AND LABORATORY MEDICINE, 2002 - 2003READING ASSIGNMENTS - page 2

WEEKS 22, Gastrointestinal Tract Chapter 18, pp. 775-842 23, 24: Hematobiliary Path Chapter 19, pp. 845-900 (Liver/Biliary Tract)

Chapter 20, pp. 902-913 (Exocrine Pancreas) Nutritional Diseases Chapter 10, pp. 436-456 Oral Cavity and Asso- Chapter 17, pp. 756-773 (Head and Neck) ciated Structures

WEEKS 26, Endocrine System Chapter 26, pp. 1121-1168 (Endocrine System) 27: Chapter 20, pp. 913-928 (Diabetes Mellitus &

Endocrine Pancreas)

WEEK 28: Diseases of the Skin Chapter 27, pp. 1170-1212 (The Skin) Diseases of Bones Chapter 28, pp. 1215-1267 (Skeletal System and and Joints Soft Tissue Tumors)

Chapter 9, pp. 388-389 (Lyme Disease)

WEEK 32: Female Genital Tract Chapter 24, pp. 1035-1079 (1079-1089 for Review)

WEEK 33: Diseases of Breast Chapter 25, pp. 1093-1118 (Chapter 8, pp. 260-325 for Review)

WEEKS 34, 35: Muscle/ Chapter 29, pp. 1269-1289 (Peripheral Nerve and Neuropathology Skeletal Muscle)

Chapter 30, pp. 1293-1355 (Central Nervous System)

-42-

THE COURSE IN PATHOLOGY AND LABORATORY MEDICINE 2002 - 2003 CASE BASED STUDY ASSIGNMENTS

WEEK 1: Laboratory Medicine Case Book Cell and Tissue Reaction Chapter 15 OR to Injury Laboratory Medicine Case Set CD ROM Environmental Pathology Chapter 20

Printed Case 1

WEEK 2: Laboratory Medicine Case Book Inflammation/Tissue Repair/ Chapters 14, 19 OR Circulatory Factors in Injury Laboratory Medicine Case Set CD ROM

Chapters 19, 24Printed Case 1

WEEK 3: Laboratory Medicine Case Book Immunity/Oncogenesis/ Chapters 8, 22 OR Neoplasia Laboratory Medicine Case Set CD ROM


WEEK 4: Laboratory Medicine Case Book Genetics Chapter 13

OR Laboratory Medicine Case Set CD ROM

Chapter 17 Printed Case 1

WEEK 5:Problems of Pregnancy/ Laboratory Medicine Case Book Developmental Pathology Chapter 27 OR Laboratory Medicine Case Set CD ROM

Chapter 37 Printed Case 1

WEEK 6: Laboratory Medicine Case Book Hematopoietic System/ Chapters 2, 23 OR Lymph Nodes & Spleen Laboratory Medicine Case Set CD ROM


WEEKS 9, 10, 11: Laboratory Medicine Case Book Cardiovascular System Chapters 7, 16 OR


Printed Case 1

WEEKS 13, 14, 15: Laboratory Medicine Case Book Kidney/Lower Urinary Tract/ Chapters 9, 10 OR Male Genital Tract Laboratory Medicine Case Set CD ROM


WEEKS 17, 18: Laboratory Medicine Case Book Respiratory System Chapters 1, 17 OR


Printed Case 1

-43-

2002 - 2003 CASE BASED STUDY ASSIGNMENTS - page 2

WEEK 22, 23, 24: Laboratory Medicine Case Book GI Tract Chapters 12, 18, 29 OR Hematobiliary Pathology Laboratory Medicine Case Set CD ROM Nutritional Diseases Chapters 14, 23, 39 Oral Cavity and Associated Printed Cases 1, 2 Structures

WEEKS 26, 27: Laboratory Medicine Case Book Endocrine System Chapters 3, 26 OR


Printed Case 1

WEEK 28: Laboratory Medicine Case Book Diseases of the Skin Chapters 20, 21 OR Diseases of the Bone Laboratory Medicine Case Set CD ROM


WEEK 32: Laboratory Medicine Case Book Female Genital Tract Chapters 30


Chapters 40Printed Case 1

WEEK 33: Diseases of the Breast Laboratory Medicine Case Book

Chapters 24 ORLaboratory Medicine Case Set CD ROM

Chapters 34Printed Case 1

WEEK 34, 35: Laboratory Medicine Case Book Diseases of Muscle/ Chapters 4, 11 OR Neuropathology Laboratory Medicine Case Set CD ROM


-44-

THE COURSE IN PATHOLOGY AND LABORATORY MEDICINE 2002 - 2003 JOURNAL CLUB ARTICLES

ALL ARTICLES ARE FROM THE NEW ENGLAND JOURNAL OF MEDICINE.

WEEK 2: PathTalk: Chimerism of the Transplanted Heart/Regeneration of the Human Heart - No Chimera?/ Can the Heart Repair Itself? Vol.346, #1, p.5/p.55/p.2.

WEEK 3: PathTalk: Comparison of Four Chemotherapy Regimens for Advanced Non-small-cell Lung Cancer/Lung Cancer-Time to Move on From Chemotherapy.Vol.346, #2, p.92/p.126.

WEEK 4: PathTalk: A Deletion Involving the Connexin 30 Gene in Nonsyndromic Hearing Impairment. Vol.346, #4, p.243.

WEEK 5: PathTalk: Birth Defects and In Vitro Fertilization/Infertility. Vol.346, #10, p.725/p.769.

WEEK 6: PathTalk: Long-Term Prognosis in Monoclonal Gammopathy of Undetermined Significance.Vol.346, #8, p.564.

WEEK 9: PathTalk: Antioxidants to Prevent Coronary Artery Disease/Antioxidant Therapy.Vol.345, #23, p.1583/p.1636..

WEEK 13: PathTalk: Urinary Tract Infections Caused by Multi-drug Resistant E. Coli/An Epidemic of Urinary Tract Infections. Vol.345, #14, p.1007/p.1055.

WEEK 17: PathTalk: Pulmonary Embolism and Air Travel/Air Travel and Venous Thromboembolism.

Vol.345, #11, p.779/p.828.

WEEK 26: PathTalk: Diet, Life Style, and Type II Diabetes Mellitus in Women. Vol.345, #11, p.790.

WEEK 28: PathTalk: IV Zoledronic Acid in Postmenopausal Women With Low Bone Mineral Density/Bisphosphonates and Osteoporosis. Vol.346, #9,

p.653/p.642.

WEEK 32: PathTalk Male Circumcision, Penile Human Papillomavirus Infection, and Cervical Carcinoma in Female Partners/Cervical Carcinoma and the Elusive Male Factor. Vol.346, #15, p.1105/9.1160.

WEEK 33: PathTalk: Breast Cancer After Prophylactiv Bilateral Mastectomy in Women with BRCA1 or BRCA2 Mutation/Mastectomy for Women with BRCA1/BRCA2.

Vol.345, #3, p.159/p.207.

WEEK 34: PathTalk: Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest/ Hypothermia to Protect the Brain/Therapeutic Hypothermia After Cardiac Arrest. Vol.346, #8, p.549/p.546/p.612.

-45-

Documents

Course - UMDNJpleiad.umdnj.edu/pathology_course/coursebk_02.doc · Web viewCourse in Pathology andLaboratory Medicine COURSE BOOK 2002 - 2003 Department of Pathology and Laboratory