Correlation Between Prostate Cancer and Arsenic

8/10/2019 Correlation Between Prostate Cancer and Arsenic

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Correlation betweenProstate Cancer andArsenicPresenter : Jevaine White

Discount Centre Pharmacy


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What is Prostate Cancer

This is where the cells within the prostate gland grows

uncontrollably.

If not controlled these cells can metastasize throughoutother areas of the body.


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The risk factors for Prostate Cancer

Exposure to Cadmium

Exposure to Arsenic

Family History

Age

Diet

Smoking

Obesity


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What is Arsenic

Symbol As

Belongs to a Group Vb

Was discovered in 1250 by Albertus Magnus

It is a naturally occurring element.

It has both metallic and non metallic properties.


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Applications for Arsenic

Arsenic was discovered as a poison in the 1950s.

Due to this knowledge it was used as a pesticide andinsecticide.

It was used as a medicine within the 19thcentury totreat patient that had acute promyelocytic leukemia,syphilis and various cancers.


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Where can Arsenic be found

Arsenic exist as both Organic and Inorganic form

(cancerous).

The inorganic form is found in industries and buildingproducts.

Whereas the organic compound is found in marine foodssuch as fish and algae.


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Correlation between Arsenic andProstate

According to Tibbetts, J. 2005 Arsenic and ProstateCancer: Acquiring Androgen Independence.

There has been a direct correlation between the dose of

Arsenic intake and the rate at which prostate cellsproliferate.

Additionally, it is reported that only a low level ofexposure to this chemical is needed to convert cells tocancerous cells.

Arsenic is also reported to be responsible for ErectileDysfunction.


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Correlation between Arsenic andProstate Contd

An experiment carried out on a control group of rats anda group exposed to sodium arsenite , over a 29 weeksperiod showed where prostate cells proliferated 2.5times faster than control cells.


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The mechanism by which Arsenic carries out its effect onthe prostate is still not understood.

However it was evident that Arsenic exposure is directlyrelated prostate cells becoming androgen indepedence.


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Environment as also played a factor in prostate cancer.

In a study carried out by (Mckay et al. 2003) showedwhere males that are from an environment (Asia) whereprostate cancer is not overwhelming have becomesusceptible to prostate cancer, once they migrate to thewestern world.


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With this evidence it has prove that race and ethnicgroup is not much of a risk factor.

However the environment plays a critical role it ProstateCancer.


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Arsenic within the Environment

With this discovery, it has lead scientist research thesources of Arsenic both within the environment and foodwe consume.

This result of this research has surprised both theresearchers and its readers.


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Chicken

The main source of protein of Jamaican citizens.

The favorite meat kind.

The cheapest meat kind.

From you can have chicken liver, chicken gizzard,chicken back , wing and chicken neck.


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Chicken Contd

These chicken are feed with chicken feedens.

Also known to the Jamaican Masses as Broiler Ration.


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Chicken Contd

In an article titled U.S. sales of widely used drug forchickens to be suspeded by Tom Watkins.

It states that Food and Drug Administration hasconfirmed the presence of Arsenic in chicken.

It was also disclosed that Arsenic was introduced to thepoultry through its feeding.

Arsenic levels was highest in the chickens liver and also

found within the chickens meat


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Water

This is essential to the survival of humans.

Water makes up more than two thirds of human bodyweight, and without water, we would die in a few days.

The human brain is made up of 95% water, blood is 82%and lungs 90%.

It is also recommended that humans should have at

least eight glasses of water per day.


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Water

Water serves the following purpose in humans

Water forms the base for saliva

Water forms the fluids that surround the joints.

Water regulates the body temperature, as the cooling &heating is distributed through perspiration.

Water helps to alleviate constipation by moving foodthrough the intestinal tract and thereby eliminatingwaste - the best detox agent.

Water helps to regulate metabolism.

Water serves as a lubricant.


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Water

In a research carried out in 1999 by T. Thompsonshowed where tap water within the US had Arseniclevels that exceeded the amount that the legislation hasallowed.

Hence this another source Arsenic to male sex.


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Fertilizer

Fertilizer, their main purpose is to provide nutrients tothe soil that will eventually become available to the plantor ground produce to utilize.

Within Jamaica fertilizers are widely used in ouragriculture industry.

Often times these fertilizers arent tested for elementssuch as Arsenic.

However, inorganic form of Arsenic is found within anumber of fertilizers.


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Pesticides

These agents are normally used to kill insects and othercreatures which are normally nuisance to the human.

The presence of Arsenic as been identified in theseagents.

However these agents are ntnormally dispose ofproperly.

Also they arent use properly.

Nor are we interesting in knowing the composition ofthese agents.

Due to these improper usage and storage of theseagents. This allows for easy ingestion and contaminationof water sources.


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Other Sources of Arsenic

Baby Formula

Motts Apple Juice

Grape Juice

Organic Brand


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Consideration

The foods we consume daily, is it safe?

Is it safe for our males to consume?

What steps are the relevant authority taking to protectour foods?


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References

Agency for Toxic Substances and Disease Registry (ATSDR). CaseStudies in Environmental Medicine: Arsenic Toxicity. 2009. Accessedat www.atsdr.cdc.gov/csem/arsenic/index.html on April 26, 2010.

Frumkin H, Thun MJ. Arsenic. CA Cancer J Clin. 2001;51;254-262.

International Agency for Research on Cancer. IARC Monographs on

the Evaluation of Carcinogenic Risks to Humans. Supplement 7:Overall Evaluations of Carcinogenicity: An Updating of IARCMonographs Volumes 1 to 42. 1987. Accessed athttp://monographs.iarc.fr/ENG/Monographs/suppl7/Suppl7-19.pdfon April 20, 2010.

International Agency for Research on Cancer (IARC). IARCMonographs on the Evaluation of Carcinogenic Risks to Humans.

Vol. 84: Some drinking-water disinfectants and contaminants,including arsenic. 2004. Accessed athttp://monographs.iarc.fr/ENG/Monographs/vol84/index.php onApril 20, 2010.


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References

Mead MN. Arsenic: in search of an antidote to a globalpoison. Environ Health Perspect. 2005;113(6):A378-A386.

US Consumer Product Safety Commission. Fact Sheet:

Chromated Copper Arsenate (CCA) -Treated Wood Usedin Playground Equipment. Accessed atwww.cpsc.gov/phth/ccafact.html on April 26, 2010.

US Department of Health and Human Services. PublicHealth Service, National Toxicology Program. Report onCarcinogens, Eleventh Edition. 2005. Accessed athttp://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s015arse.pdf on April 20, 2010.


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References

US Department of Labor, Occupational Safety & HealthAdministration. Arsenic Standards. 2008. Accessed atwww.osha.gov/SLTC/arsenic/standards.html on April 26,

2010.

US Environmental Protection Agency. Integrated RiskInformation System: Arsenic, inorganic (CASRN 7440-38-2). 1998. Accessed atwww.epa.gov/ncea/iris/subst/0278.htm on April 22,

2010.

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Correlation Between Prostate Cancer and Arsenic