PowerPoint Megacompetition in Higher Education
and Collaboration with Industry
Fellow university presidents and other participants;
*
Megacompetition in Higher Education
Digitalization: Development of high-speed digitalized communication, data storage and information processing
Sharing knowledge: Ideas are shared by global community as soon as they are generated and publicized
Financial pressure: Universities inevitably compete due to financial pressures
Collaboration with Industry
Digitalization: Collaboration can be much more efficient than before
Sharing knowledge: Universities and Industries can share knowledge for mutual interests; not only for science and technology but also for economic and legal issues
Financial pressure: Both universities and industries face financial pressures
Innovation through competition and collaboration
*
Knowledge Interaction Model
Knowledge Globalization Model
University and Industry in Knowledge-Sharing Global Community
Value of original ideas: IP and Standards
Real-time collaboration for global interests
University
Industry
Merits of Pacific Rim Universities for Innovation
Diversity of human resources
Abundance of challenging problems to be discovered and to be solved: e.g., medical care, infrastructure, energy, environment, transportation, disaster prevention, security, communication, everyday life support, legal systems, economic systems, finance and management, fiscal policy, educational systems …
Possibilities for new educational systems: can be relatively free from conventional style of higher education
Motivation for economic growth and its sustainability

*
University, Industry and (Central and Local) Government
University Should generate innovative, generic research results, motivated by goals for mid- or long-range social profit, not by goals for solving toy problems.
Industry Should generate innovative ideas and management systems for developing social and industrial applications, business models and markets, motivated by goals for short- or mid-range social profit, not by goals for expecting innovation only to universities.
Government Should generate innovative policies and systems of financial support that truly encourage and promote open and deregulated collaboration between universities and industries.
Requirements for Universities
Research: See above.
Knowledge: Active role-taking as sites of knowledge creation and distribution
Intellectual property: Sophisticated innovation, and active collaboration with industry, for sharing knowledge in the global community
International and domestic standards: Active participation in generating benefits for the global community, both in de jure, and in de facto, manners
*
Selective and sensitive detection
thousands of charged metabolites
26 x CE systems
5 x LC systems
2 x GC/MS systems
2 x TripleQ-MS/MS systems
13 x ESI-TOFMS systems
3 x Q-TOFMS system
Innovation in Metabolome Analysis and its Distribution in Market (1)
Institute for Advanced Biosciences (IAB)
MS
CE
(the collection of all
metabolites in the cell)
The first example of innovative projects in University-Industry Collaboration is Innovation in Metabolome Analysis and its Distribution in Market at Institute for Advanced Biosciences(IAB), Keio University.
The IAB is located in Tsuruoka city in Yamagata prefecture, in the northern part of Japan, about a one-hour flight from Tokyo. The institute is a full-fledged laboratory for bioresearch, established at Keio’s Tsuruoka Town Campus in April 2001.
The IAB, using leading-edge biotechnology, comprehensively measures and analyzes the cellular activities of organisms and microbes, and simulates various cell functions. The IAB has attracted world attention as a pioneer in “integrated systems biology”. This institute is developing one major part of this new, IT-driven bioscience
At the completion of the genome project, focus has shifted to understanding how living systems use and interpret information encoded in the genes to produce the phenome, i.e., their outward, physical manifestations. Studies are carried out on the levels of transcriptome, proteome, and more recently, metabolome.
The metabolome is the complete set of small molecules in the cell that are believed to be the main effectors of phenotype. IAB is at the forefront of metabolome research using cutting-edge technologies. Metabolome analysis is indispensable in interpreting the biochemical meaning of DNA micro array and proteomics data.
IAB’s core technique is capillary electrophoresis coupled to mass spectrometry, and our laboratories are equipped with many top-of-the-line CE systems and mass spectrometers. Thousands of metabolites can be efficiently separated by CE according to their sizes and charges, then identified and quantitated by MS.
The projects include the development of a high-throughput comprehensive chemical analysis, bioinformatics to reconstruct and simulate metabolism, and applications of metabolome data to medicine, metabolic engineering and agriculture.
*
and Technology, Japan
Industry/Government Partners
D-,L-lactic acid using microorganism
Proteome Analysis, Metabolome Analysis, Flux Analysis
Analyze metabolic pathways producing high D-lactic acid
Design E.Coli producing high D-lactic acid
Design microorganism producing high L-lactic acid
Metabolome analysis
of microorganism
Metabolome analysis
of food
Metabolome analysis
of biological sample
To have a grasp of the mechanism of the microorganism ’s production
To have a grasp of
the biological status
New medicine
To find the biomarker
Discovery of new antibiotics
etc.
Innovation in Metabolome Analysis and its Distribution in Market (2)
Pharmaceutical
companies
The imports of metabolome analysis cut across many fields of application. For instance, by studying changes in metabolite profiles in human biofluids such as blood and urine, we will be able to tell early progression of a disease, and medicine, as we know it, will be changed from being reactive to predictive. In food science, metabolomic data can help in the rational design of approaches for improving fermentation productions such as amino acids and nutritional value and flavor of food.
*
-
Amplifier and Laser
Innovation in Plastic Optical Fiber and its Distribution in Market(1)
Photonics Polymer Project
The second example of innovative projects in University-Industry Collaboration is Innovation in Plastic Optical Fiber and its Distribution in Market, Photonics Polymer Project by Prof. Koike at Keio University
This figure shows the basic concept of Photonics Polymer Project by Prof. Koike at Keio University.
Photonics polymers have been widely used as key materials for various photonics polymer devices such as pickup lenses for DVD players, LCD devices, and polymer optical fibers. However, it seems that photonics polymers have been evaluated with almost no fundamental debate linking polymer material science and optics.
This project has started its research by breaking down those academic boundaries, and focused on the evaluation about how light relates to polymers. Based on those basic researches, this project has proposed and demonstrated photonics polymers with new optical functions for the application in photonics fields.
(1) Where there are heterogeneities of refractive-index on the order of more than several dozen microns, light is refracted or reflected. Utilizing this phenomenon, this project has proposed and developed Graded-Index Polymer Optical Fibers (GI-POF), which allow high-bandwidth data transmission of gigabit per second for the first time in the world.
(2) When the size of heterogeneities becomes about one micron, no refraction is exhibited and light causes scattering. He proposed and demonstrated “thin and bright LCD backlights” by adding scattering function to polymer light guide plates. The backlight proposed by this project is the best seller for notebook type computers in the world.
(3) When the size becomes that of monomer units, no more scattering is caused. Instead, polarizability anisotropy is formed within polymers to cause birefringence by orientation of polymer chains. The zero-birefringence optical polymers that exhibit no birefringence was proposed for the first time by this project. It would be possible to improve the quality and reduce manufacturing cost of LCD television significantly by using zero-birefringence optical polymers.
*
High-Speed Internet
Core Network
Fig. 2 “Fiber-to-the-Display” by Photonics Polymer Project with GigaHouseTown Project
In collaboration with
IBM Japan
(B) Material Science and Material Technology:
Innovation in Plastic Optical Fiber and its Distribution in Market(2)
As shown in the previous Slide, Photonics Polymer Project is conducting a thorough study of the optical properties of novel photonics polymer, such as how light propagates in polymers and light interacts with polymers, and the development of their basic findings into a wide range of applications.
Furthermore, they are focusing on how they can use these novel technologies to bring about a real fruitfulness in our lives. Seeking for the true wealth of life, the concept of “Fiber-to-the-Display” was born. This figure shows the concept.
*
RO satellite and UDLR technology (UDLR)
Multicast technology
Multicast streaming
IPv6 etc
Hlaing Campus, Yangon, Myanmar
Bangladesh University of Engineering and Technology
Mongolian University of Science and Technology etc
Supported by advanced technologies developed by
Ac/Gov/Industry
Innovation in ICT
SOI (School on Internet) Asia Project
SOI-Asia Educational Collaboration among Universities in Asia
*
DENSO Corp.
IBM Japan, Ltd.
Industry/Government Partners
Innovation in ICT
SOI (School on Internet) Asia Project
Content Development for
Thank you!
We will be celebrating our 150th anniversary in 2008, and have taken this approaching milestone as an opportunity to reinvent ourselves. As you can see, Keio is taking some significant steps toward its goal of becoming a truly globally-oriented, world-class institution of higher education.
We are excited about these recent developments and look forward to collaborating on some of them with you in the future.
Thank you very much.