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ii CONTENTS Page CONTENTS .......................................... ii CHAPTER 1 INTRODUCTION ............................ 1 1.1........................................... Back ground .................................... 1 1.2........................................... Obje ctives .................................... 2 CHAPTER 2 LITERATURE REVIEW ....................... 3 2.1........................................... Embr iology of Respiratory System .............. 3 2.2.1. Trachea, Bronchi, and Lungs .................. 6 2.2.2. Maturation of the Lungs ....................7 2.2.3. Surfactant Formation and Physiology ....................8 2.2........................................... Resp iratory Distress in Newborn ............... 11 2.2.1. Transient Tachypnea of the Newborn ...............14 2.2.2. Respiratory Distress Syndrome ................ 14

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2CONTENTSPageCONTENTS ........................................................................................................................................................................................................................... iiCHAPTER 1 INTRODUCTION .................................................................. 11.1..........................................................................................................Background ................................................................................................ 11.2..........................................................................................................Objectives .................................................................................................. 2CHAPTER 2 LITERATURE REVIEW ...................................................... 32.1..........................................................................................................Embriology of Respiratory System ............................................................ 2.2.1.!rac"ea# Bronc"i# and $ungs . . %2.2.2.&aturation of t"e $ungs ......... .'2.2.. Surfactant (ormation and P"ysiology . . )2.2..........................................................................................................Respiratory *istress in +e,born ............................................................... 112.2.1. !ransient !ac"ypnea of t"e+e,born.....................................1-2.2.2. Respiratory *istress Syndrome........................................ 1-2.2..&econium .spiration Syndrome........................................1/2.2.-.0nfections ......................................................... 1/2.2./.$ess 1ommon 1auses ...................................... 1%2...........................................................................................................Respiratory *istress Syndrome in +e,born .............................................. 1'2..1...............................................................................................Etiology .............................................................................................. 1)2..2...............................................................................................1linicalPresentation ............................................................................ 2232.................................................................................................Pat"ology ............................................................................................ 22..-...............................................................................................Pat"op"ysiology ................................................................................ 2-2../...............................................................................................*iagnosis ............................................................................................ 2/2..%...............................................................................................*ifferential *iagnosis ........................................................................ 2)2..'...............................................................................................Prevention ........................................................................................... 222..)...............................................................................................!reatment ........................................................................................... 222..2...............................................................................................1omplications ..................................................................................... CHAPTER 3 CASE REPORT ...................................................................... 35CHAPTER 4 DISCUSSION & SUMMARY ...............................................4.1. *iscussion .................................................................................... 2'4.2. Summary ...................................................................................... 2'REFERENCES ............................................................................................... 29DAFTAR TABEL +omor 3udul 4alaman4!abel 2.1. !aksonomi !anaman 5unyit 6Curcuma domestica Val7 /!abel 2.2. 5omposisi 5imia Rimpang 5unyit '!abel 2.. !aksonomi 3amur Malassezia furfur 1)!abel -.1. *esain Pra8 eksperimen 2'DAFTAR GAMBAR+omor 3udul 4alaman9ambar 2.1. Struktur 5imia,i Curcuminoid )9ambar 2.2. 5edua Bentuk Tautomeric Curcumin 29ambar 2.. 4asil &etabolit Curcumin di dalam !ubu" 1-9ambar .1. 5erangka 5onsep Penelitian 2/