COLLEGE OF SCIENCE+

HONORS COLLEGE

Sandra Loesgen

Chemistry

Gilbert Hall 333

sandra.loesgen@oregonstate.eduhttp://loesgenlab.org

Prof. Sandra Loesgen Department of Chemistry

Drug Discovery from Microorganisms:Microbial natural products are a rich source for new chemistry useful as antibacterial, anti-cancer, and antiviral therapeutics.

Research opportunitiesChemical exploration of fungi and bacteria:• Isolation and identification of microorganisms• Chemical screening and bioactivity testing of

microbial metabolites• Cell-based assays to identify antibiotic and

cytotoxic activity• Isolation and characterization of complex

natural products• Can we influence the chemistry? Why is it

made, when, how?

Vrushali Bokil

Mathematics

Malgo Peszynska

Mathematics

Kidder 292a 541-737-9847mpesz@math.oregonstate.edu

Malgo PeszynskaMathematics

Data: experiment vs reconstruction Computing: accuracy vs Efficiency Modeling:

graphs vs functions reaction vs diffusion linear vs nonlinear discrete or continuum

Ex.: Multiple scales and phases Thesis topics and opportunities “Differential Equations with Graphs” “Phase transitions: ice-cream or latte? “Modeling diffusion and aggregation” “Network modeling” …

Applied and computational mathematics. Analysis; Algorithms; Modeling; Data.Applications: Geosciences; (Alternative) Energy; Materials; Environment.

NSF-DMS grant 2015-2019 “Phase transitions across the scales”

Conflicts in Silicio(in computational modeling)

Flow

Biofilmphase

12h 22h

http://www.math.oregonstate.edu/~mpesz/people.html

Richard Cooley

Biochemistry & Biophysics

Cooley and Mehl Labs: Development and applications of Genetic Code Expansion

Directed evolution to make new enzymes

Enzyme Optimization• Kinetics• Thermodynamics

Genomically recoded organisms

Organic Synthesis of new amino acids

Organic synthesisMolecular Biology

• Cloning • PCR

Protein expression• In vivo• In vitro

Structural Biology• X-ray crystallography

Characterize new protein material

Email: cooleyr@oregonstate.edu, Ryan.Mehl@oregonstate.edu

“Protein Engineering”

May Nyman

Chemistry

METAL OXIDE CLUSTERS

May NymanProfessorGilbert 103541-737-1116May.Nyman@oregonstate.edu

Jaga Giebultowicz

Integrative Biology

Jaga Giebultowicz labWe study rhythms of life called circadian rhythms

All organisms have biological clock that generate circa 24 h rhythms

Animals are active at certain time of day or night Humans have times of high and low alertness

Biological clocks regulate physiological and molecular rhythms: what if they are broken?

What you could study in our lab:• Genome wide circadian gene

expression• How gene expression changes during

aging?• How to repair old biological clocks?• Effects of blue LED light on aging

Clock neurons in Drosophila brain

? ?

Kevin Brown

CBEE & Pharmacy

Kevin Brown: Complex SystemsPharmaceutical Sciences and CBEEOffice: PHAR Room 317email: kevin.brown@oregonstate.edu

Systems Biology

Systems Neuroscience Data Mining

Cognitive Science

Francis Chan

Integrative Biology

Science of a Changing Ocean

Francis Chan, Dept of Integrative Biologyfrancis.chan@oregonstate.edu

Elisar Barbar & Nathan Jespersen

Biochemistry & Biophysics

ALS 2133541-737-4143Elisar.barbar@oregonstate.edu

Elisar BarbarBiochemistry and Biophysics

Thesis topic ideas/opportunitiesProtein Biophysics and/or in cell work:• Viral parasitism – Ebola/rabies/rotaviruses• Crystallin aggregation – Cataracts • Motor protein regulation – NeurodegenerationComputational work/Bioinformatics:• LC8 motif analysis – Hub regulation• Database for LC8 interactions

Our primary focus is elucidation of the molecular structure, assembly and regulation of protein interaction networks. The proteins we study are associated with Huntington’s disease, cataracts, and viral infections.

Protein Interaction Networks/Hubs

Rabies-Host Interactions

Tom Sharpton

Microbiology & Statistics

The Sharpton Lab Studies the How the Gut Microbiome Impacts Health and Evolution

Depts. Microbiology & Statisticsthomas.sharpton@oregonstate.edu@tjsharptonlab.sharpton.org

Lubchenco/Menge Lab

Integrative Biology

Welcome to the Lubchenco/Menge Lab

http://lubmengelab.oregonstate.edu/Contact Brittany Poirson - Research Technician at

poirsonb@science.oregonstate.edu

Our lab has diverse interests that are united by a common goal: understanding the dynamics of natural ecological communities. Our insights into community regulation, biodiversity, and global change are generated primarily by research on rocky shores and marine ecosystems. We approach questions at a variety of scales and with a diversity of tools ranging from biochemical studies at the suborganismal level, to controlled field experiments in intertidal communities, to biogeographic comparisons among the coasts of Oregon, New Zealand, and Chile.

Hoewoon Kim

Mathematics

Hoe Woon KimMathematicsResearch Field:Partial Differential Equations, Mathematical Physics and ProbabilityResearch Group:Probability

Contact InfoPrimary Title:Senior InstructorEmail Contact:kimho@math.oregonstate.eduVoice Contact:(541) 737-5140Fax Contact:(541) 737-0517Office:KIDD 054Office Hours:MWF 1:00-1:50 pm or by appointment

COLLEGE OF SCIENCE

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