COLLEGE OF MEDICINE CURRICULUM VITAE · COLLEGE OF MEDICINE CURRICULUM VITAE Henry T. Hoffman, M.D. Page 5 27th Annual, “Common Problems in Laryngology” and “Tumors of the Larynx

COLLEGE OF MEDICINE CURRICULUM VITAE

Henry T. Hoffman, M.D. September 28, 2007

I. EDUCATIONAL AND PROFESSIONAL HISTORY A. Higher Education 1976 B.S. University of the South, Sewanee, Tennessee 1980 M.D. University of California, San Diego, California 1989 M.S. University of Michigan, Ann Arbor, Michigan Postgraduate Medical Education 1980-81 General surgery residency: LaCrosse Lutheran Hospital, LaCrosse Wisconsin 1981-85 Residency, Otolaryngology, University of Iowa Hospital and Clinics 1987-88 Fellowship, Facial Plastics and Reconstructive Surgery, University of Michigan 1988-89 Fellowship, Head and Neck Surgery, University of Michigan Certification and Licensure American Board of Otolaryngology, Original, October 1985 Iowa Board of Medical Examiners, License Number 23662, expires July 1, 2008 B. Professional and Academic Positions

Academic University of California, San Diego, Department of Otolaryngology

1989 Assistant Adjunct Professor University of Iowa College of Medicine, Department of Otolaryngology—Head and Neck Surgery

1990 Assistant Professor 1993 Associate Professor 2000 Professor

Administrative University of Iowa College of Medicine, Department of Otolaryngology—Head and Neck Surgery 1990-present Director, Head and Neck Oncology 1990-present Director, Voice Clinic C. Honors and Awards 1974-75,75-76 All-Conference Basketball (College Athletic Conference) 1975-1976 Phi Beta Kappa; Summa Cum Laude; Omicron Delta Kappa 1976 NCAA Post-Graduate Scholarship to Medical School 1992-1993 Medical Student (M3) Teaching Award (one of five finalists) 1992 Otolaryngology Department "Barry Anson Teacher of the Year" Teaching Award 1995 American Academy of Otolaryngology Honor Award 1995-2000 Associate Editor, Head and Neck Journal 1996 America’s Best Doctors (Midwest) 1997 Who’s Who in Medicine and Healthcare Second Edition 1999 Otolaryngology Department "Barry Anson Teacher of the Year" Teaching Award 2000-2005 Clinic Reviews Editor, Head and Neck Journal 2000-2003 Cancer Liaison for the State of Iowa, American College of Surgeons 2000-2003 Executive Council Member, American Head and Neck Society 1999-present America’s Best Doctors 2005-present America’s Top Doctors for Cancer


Henry T. Hoffman, M.D. Page 2

2003 Editorial Board, AJCC Staging Manual Sixth Edition, Head and Neck Sites 2006 Editorial Board, AJCC Staging Manual Seventh Edition, Head and Neck Sites 2006 Mosher Award for Triologic Thesis 2007 AHNS Presidential Citation II. TEACHING A. Clinical Teaching 1990-present Operating Room 1990-present Inpatient Ward 1990-present Otolaryngology Clinic 1990-present Voice Clinic 1990-present Head and Neck Multidisciplinary Treatment Planning Conference 1990-00 M2 lecture “Voice Disorders” 1990-95 M3 lecture “Head and Neck Oncology” 1990-00 Department Laryngology/Pathology Conference 1993 Special Reading in Otolaryngology (course #068-998), Lucy Karnell, grad student Ph.D. Theses Committees

Julie Barkmeier, 1991-1994, Scanning Electromicroscopic Investigation of Laryngeal Nerves, University of Iowa, (Thesis successfully defended May 1994).

Kang Liu, 1994-1996, Neurophysiology of the Larynx: Coordinated Reflex Response to Laryngeal Stimulation in Feline Model, University of Iowa (Thesis successfully defended May 1996).

Lucy Karnell, 1994-1997, Quality of Life Measures of Speech Outcomes within Head and Neck Cancer Patients, University of Iowa. (Thesis successfully defended July 1997).

Eileen Finnegan, 1995-1998, Evaluation of Coordinated Electromyographic and Pressure Changes During Phonation, University of Iowa (Thesis successfully defended March 1998).

Douglas Montequin, 1998, Special Mechanisms of Voice Production, University of Iowa. Eric Hunter, 2001, University of Iowa. B. Otolaryngology Resident and Fellow Research Projects Supervised

Haller J. 1990-91, Head and Neck Oncology, “Analysis of effect of intra-arterial chemotherapy on subsequent microvascular anastomosis.” Tsen D. 1990-91, Laryngeal Physiology, “Effect of medialization laryngoplasty on vocal output in a canine model.” Peterson KL. 1991-92, Laryngeal Physiology Peterson KL, Hoffman HT, VanDemark D, Barkmeier JM: “Botulinum Neurotoxin A Injection to

the Pharyngeal Constrictor Muscles After Total Laryngectomy.” Presented at the Southern Section of the Triologic Society Sea Island, GA. January 17, 1992.

Peterson KL, Verdolini-Marston K, Barkmeier JM, Hoffman HT: "Comparison of Aerodynamic and Electroglottographic Parameters in Evaluating Clinically Relevant Voicing Patterns.” Annals of Otology, Rhinology, and Laryngology, 103(5):335-345, 1994.

Gartlan M.G. 1992-93, Laryngeal Neurophysiology Gartlan MG, Hoffman HT: "Crystalline Preparation of Botulinum Toxin Type A (Botox):

Degradation in Potency with Storage.” Otolaryngology--Head and Neck Surgery,



108(2):135-140, 1993.

Gartlan MG, Peterson KL, Hoffman HT, Luschei ES, Smith RJH: "The Bipolar Hooked-Wire Electromyographic Technique in the Evaluation of Pediatric Vocal Cord Paralysis." Annals of Otology, Rhinology, and Laryngology, 102(9):695-700, 1993.

Jaffe D.M. 1994-97, Laryngeal Neurophysiology Jaffe DM, Solomon NP, Robinson RA, Hoffman HT, Luschei ES: “Comparison of Concentric

Needle Versus Hooked Wire Electrodes in the Canine Larynx.” Otolaryngology Head and Neck Surgery, 118:655-62, 1998.

Min Y. 1992-94, Laryngeal Neurophysiology Min YB, Finnegan EM, Hoffman HT, Luschei ES, McCulloch TM: “A Preliminary Study of the

Prognostic Role of Electromyography in Laryngeal Paralysis.” Otolaryngology--Head and Neck Surgery, 111(6):770-775, 1994.

Min YB, Luschei ES, Finnegan EM, McCulloch TM, Hoffman HT: “Portable Telemetry System for Electromyography.” Otolaryngology--Head and Neck Surgery, 111(6):849-852, 1994.

Beatty MM. 1997-98, Laryngeal Physiology Beatty MM, Hoffman HT: “The Impact of Laryngeal Paralysis and its Treatment on the Glottic

Aperture and Upper Airway Flow Characteristics During Exercise.” Otolaryngology Head and Neck Surgery, 120(6):819-823, 1999. (Presented at AAO-HNS Research Forum, September 9, 1997).

Koch BB. 1997-99, Head and Neck Oncology Koch BB, Karnell LH, Hoffman HT, Apostolakis LW, Robinson RA, Zhen W, Menck HR: “National

Cancer Data Base Report on Chondrosarcoma of the Head and Neck.” Head and Neck, 22(4):408-25, 2001.

Koch BB, Hoffman HT, Karnell LH, Robinson RA, Zhen W, Menck HR: “National Cancer Data Base Report on Head and Neck Verrucous Carcinoma.” Submitted to Laryngoscope March 1999.

Apostolakis LW. 1997-98, Head and Neck Oncology Smith R.B., Apostolakis L.W., Karnell L.H., Koch B.B., Robinson R.A., Zhen W., Menck H.R.,

Hoffman H.T.: “National Cancer Data Base Report on Osteosarcoma of the Head and Neck.” Cancer, 98(8):1670-80, 2003.

Ali T. 1998-99, Head and Neck Oncology, “Outcomes Analysis of Oral Cavity Cancer with and

without Human Papillomavirus.”

C. Institutional Conferences, Grand Rounds, Journal Clubs, Etc. 1991-00 University of Iowa Basic Science Course, 8 hours.

1991-98 University of Iowa Medical School – Introduction To Clinic Medicine: Common Voice Disorders, 1 hour.

1991-00 Saturday Morning Otolaryngology Rounds, 2 hours per week. 1993 Advanced Biomedical Studies 50:199, 2-501 BSB, 2 hours, "Cancer of the Head

and Neck" Course Director, Jose Assouline, Ph.D. 1997 Wendell Johnson Speech Pathology Graduate School “Communication Problems

Associated with Head and Neck Cancer” 2/6/97, Surgical Treatment of Laryngeal Cancer.

1997 Graduate Dental School (prosthodontics class) 2/26/97, Head and Neck Cancer Overview.

1999 University of Iowa Thoracic Malignancies Conference, 3/12/99, Treatment of Hypopharyngeal Cancer.



Teaching Committees American Head and Neck Society Education Committee

Comprehensive Cancer Control Committee Member, Report to the State of Iowa Legislature, January 2002.

Local and Regional CME Talks Director and Lecturer University of Iowa Head and Neck Cancer and Reconstructive Surgery Course, University of Iowa Hospitals and Clinics, Iowa City, Iowa 1991 24th Annual Course, May 20-24, 1991 1992 25th Annual Course, June 1-5, 1992 1993 26th Annual Course, June 8-12, 1993 1994 27th Annual Course, June 14-18, 1994 1995 28th Annual Course, June 6-10, 1995 1996 29th Annual Course, June 18-22, 1996 1997 30th Annual Course, June 17-21, 1997 1998 31st Annual Course, June 9-13, 1998 1999 32nd Annual Course, June 8-12, 1999 2000 33rd Annual Course, June 13-17, 2000 2001 34th Annual Course, June12-16, 2001 2002 35th Annual Course, June 11-15, 2002 2003 36th Annual Course, June 10-14, 2003 2004 37th Annual Course, June 7-11, 2004 2005 38th Annual Course, June 6-10, 2005 2006 39th Annual Course, June 12-16, 2006 2007 40th Annual Course, June 11-16, 2007

Co-Director and Lecturer University of Iowa Head and Neck Laser Course, June 7, 1993, Iowa City, Iowa Lecturer Sisson International Head and Neck Workshop, Vail, Colorado

14th Annual, "Paranasal Sinus Neoplasia," February 22-29, 1992 15th Annual, "Innovations in Head and Neck Surgery," February 20-27, 1993 16th Annual, "Sinus-Facial Plastic-Laryngology-Head & Neck," March 12-19, 1994 17th Annual, "Sleep Disorders-Head & Neck Sinus-Facial Plastic," February 11-18, 1995 18th Annual, “Non-Surgical Management of Benign Laryngeal Pathology and Voice Disorders,” February 10-17, 1996 19th Annual, “Glottal Incompetence: Paralysis and Paresis”, “Standard of Care for Laryngeal Cancer in the U.S.” and “Laryngology: Problem Cases in Diagnosis and Treatment,” February 8-15, 1997 20th Annual, “Benign Larynx: Common Problems with Tough Solutions,” February 7-14, 1998 21st Annual, “Controversies in Laryngology,” January 23-30, 1999 22nd Annual, “Laryngology Panel,” January 30-February 4, 2000 23rd Annual, “Advanced Cancer: We Have Failed, What’s Next, Bench to Bedside, Early Trials

with Great Potential,” February 3-10, 2001 24th Annual, “Treatment Updates for Benign Laryngeal Disease,” February 9-16, 2002 25th Annual, “Controversies in Neurolaryngology,” February 8-15, 2003 26th Unable to attend



27th Annual, “Common Problems in Laryngology” and “Tumors of the Larynx and Trachea,” February 6-11, 2005 28th Annual, Panelist, “Case Studies in Laryngology” and “The Neck Mass: Benign vs. Malignant,” February 7-9, 2006

III. SCHOLARSHIP Publications (Peer Reviewed) Hoffman HT, Davidson TM, Fierer J. The Effect of Hemolyzed Erythrocytes on the Virulence of Escherichia coli and Normal Human Oral Flora in a Mouse Model. Laryngoscope 91(6):910-917, 1981. Hoffman HT, Davidson TM, Ward CF, Smith NT, Herbst KD. Anesthesia in Septorhinoplasty: Effects of Halothane vs. Nitrous Narcotic on Bleeding. Archives of Otolaryngology, 108:83-86, 1982. Hoffman HT, Bolz EA. Letter: The Superiorly Based Auricular Flap. American Journal of Otolaryngology, 9(5):232-237, 1988. Hoffman HT, Koconis CA, Landis EE: "Upper Airway Obstruction Associated with Large Bore Nasogastric Tube." Southern Medical Journal, 81(10):1333, 1988. Hoffman HT, LaRouere M. A Simple Bolster Technique for Skin Grafting. Laryngoscope, 99(5):558-59, 1989. Hoffman HT, Baker SR. Nasal Reconstruction with the Rapidly Expanded Forehead Flap. Laryngoscope, 99(10 Pt1):1096-1098, 1989. Bradford CR, Hoffman HT, Wolf GT, Carey TE, Baker SR, McClatchey KD. Squamous Carcinoma of the Head and Neck in Organ Transplant Recipients: Possible Role of Oncogenic Viruses. Laryngoscope, 100(2 Pt 1):190-194, 1990. (Selected for AAO-HNS home study course). Hoffman H, Subnani M, Cha M, Kidd L, Landman J, Tooley R, Carey TE. Calcium Regulation of Antigen Expression on Normal and Malignant Human Squamous Cells In Vitro. Archives of Otolaryngology, 116:299-303, 1990. Hoffman HT, Panje WR. Letter to Editor: Intraoperative Videolaryngoscopy. Laryngoscope, 100(6):671, 1990. Hoffman HT, Baker SR. Tracheostoma Diverticulum Following Tracheoesophageal Puncture. Archives of Otolaryngology, 116(9):1074-1076, 1990. Burkey BB, Hoffman HT, Baker SR, Thornton A. Chondrosarcoma of the Head and Neck. Laryngoscope, 100(12):1301-1305, 1990. McClatchey KD, Wells MD, Hoffman HT. An Uncommon Case of Parotid Sialolithiasis. Annals of Dentistry, 50(1):23-24, 1991. Hoffman HT, Brunberg JA, Winter P, Sullivan MJ, Kileny PR. Arytenoid Subluxation: Diagnosis and Treatment. Annals of Otology, Rhinology, & Laryngology, 100(1):1-9, 1991. Robbins KT, Varki NM, Storiolo AM, Hoffman HT, Hoffman RM. Drug Response of Head and Neck Tumors in Native-State Histoculture. Archives of Otolaryngology, 117(1):83-86, 1991.



Hoffman HT, Harrison N, Sullivan MJ, Robbins KT, Ridley M, Baker SR. Mandible Reconstruction with Vascularized Bone Grafts. Archives of Otolaryngology, 117:917-925, 1991. Hoffman HT, Sullivan MJ, Winters P. Gelfoam Injection for Vocal Cord Paralysis Prior to Radiation Therapy. Ear, Nose, & Throat Journal, 70(6):385-386, 1991. Hoffman HT, Sillman JS. The Thyroplasty Retractor. Otolaryngology--Head & Neck Surgery, 104(4):553-554, 1991. Darrow DH, Hoffman HT, Barnes GJ, Wiley CA. Management of Dysphagia in Inclusion Body Myositis. Archives of Otolaryngology, 118(3):313-317, 1992. Olson EM, Wright DL, Hoffman HT, Hoyt DB, Tien RD. Frontal Sinus Fractures: Evaluation of CT Scans in 132 Patients. American Journal of Neuroradiology, 13(3):897-902, 1992. Laman SD, Whitaker DC, Hoffman HT, Jebsen P. Hyperbaric Oxygen and Mohs Micrographic Surgery in the Treatment of Osteoradionecrosis and Recurrent Cutaneous Carcinoma. Journal of Dermatologic Surgery and Oncology, 18:579-583, 1992. Wright DL, Hoffman HT, Hoyt DB. Frontal Sinus Fractures in the Pediatric Population. Laryngoscope 102(11):1215-1219, 1992. Talmi YP, Hoffman HT, McCabe BF. Syndrome of Inappropriate Secretion of Arginine Vasopressin in Patients with Cancer of the Head and Neck. Annals of Otology, Rhinology, & Laryngology, 101(11)946-949, 1992. Gartlan MG, Pinkston DR, Hoffman HT. Pathology Quiz Case: Ductal Cyst. Archives of Otolaryngology, 118(11):1266-1268, 1992. Hoffman HT, Jalowayski A, Robbins KT, Feldman J. Oronasal Reconstruction with Local Mucoperiosteal and Free Latissimus Dorsi Flaps. Archives of Otolaryngology, 118(11):1238-1241, 1992. Simonson TM, Yuh WT, Ryals TJ, Farrar GR, Rezai K, Hoffman HT. MR Imaging and HMPAO Scintigraphy in Conjunction with Balloon Test Occlusion: Value in Predicting Sequelae after Permanent Carotid Occlusion. American Journal of Roentgenography, 159(5):1063-1068, 1992. Braganza RA, Tien R, Hoffman HT, Haghighi PH. Amyloid of the Facial Nerve. Laryngoscope, 102(12 Pt 1):1372-1376, 1992. Redleaf MI, Fyler EA, Frodel JL, Hoffman HT. Custom Septal Button. Otolaryngology--Head & Neck Surgery, 108(2):196-198, 1993. Gartlan MG, Hoffman HT. Crystalline Preparation of Botulinum Toxin Type A (Botox): Degradation in Potency with Storage. Otolaryngology--Head & Neck Surgery, 108(2):135-140, 1993. Funk GF, Hoffman HT, Carter KD. Special Considerations in the Management of Malignant Skin Lesions About the Eye. Otolaryngologic Clinics of North America, 26(2):215-230, 1993. Gartlan MG, Haller JR, Hoffman HT, Dolan KD. Fibrosarcoma of the Posterior Neck. Annals of Otology, Rhinology & Laryngology, 102(10):820-822, 1993. Frodel JL, Funk GF, Capper DT, Fridrich KL, Blumer JR, Haller JR, Hoffman HT. Osseointegrated Implants: Comparative Study of Bone Thickness in Four Vascularized Bone Flaps. Plastic & Reconstructive Surgery, 92(3):449-455, 1993.



Gartlan MG, Peterson KL, Luschei ES, Hoffman HT, Smith RJH. Bipolar Hooked-Wire Electromyographic Technique in the Evaluation of Pediatric Vocal Cord Paralysis. Annals of Otology, Rhinology, & Laryngology, 102(9):695-700, 1993. Arcuri M, LaVelle W, Higuchi KW, Hoffman H. Combined Percutaneous-Permucosal Titanium Implants for Retention of a Maxillary Prosthesis: A Clinical Report. Journal of Prosthetic Dentistry, 7(4):288-290, 1993. Peterson KL, Verdolini-Marston K, Barkmeier JM, Hoffman HT. Comparison of Aerodynamic and Electroglottographic Parameters in Evaluating Clinically Relevant Voicing Patterns. Annals of Otology, Rhinology, & Laryngology, 103(5 Pt 1):335-346, 1994. Min YB, Luschei ES, Finnegan EM, McCulloch TM, Hoffman HT. Portable Telemetry System for Electromyography. Otolaryngology--Head & Neck Surgery, 111(6):849-852, 1994. Min YB, Finnegan EM, Hoffman HT, Luschei ES, McCulloch TM. A Preliminary Study of the Prognostic Role of Electromyography in Laryngeal Paralysis. Otolaryngology--Head & Neck Surgery, 111(6):770-775, 1994. Verdolini K, Hoffman HT, McCoy S. Nonspecific Laryngeal Granuloma: A Case Study of a Professional Singer. Journal of Voice, 8(4):352-358, 1994. Angeli SI, Alcade S, Hoffman H, Smith RJ. Langerhans' Cell Histiocytosis of the Head and Neck in Children. Annals of Otology, Rhinology & Laryngology, 104(3):173-180, 1995. Olson GT, Moreano EH, Arcuri MR, Hoffman HT. Dental Protection During Rigid Endoscopy. Laryngoscope 105(6):662-3, 1995. Funk GF, Laurenzo JF, Valentino J, McCulloch TM, Frodel JL, Hoffman HT. Free-Tissue Transfer Reconstruction of Midfacial and Cranio-Orbito-Facial Defects. Archives of Otolaryngology, 121(3):293-303, 1995. Seabold JE, Weber PC, Thompson BH, Rezai K, Madsen MT, Hoffman HT. Simultaneous Dual Acquisition Indium-111 Leukocyte (IN-WBC)/Tc-99M MDP Bone SPECT Scintigraphy in the Evaluation of Postoperative and Recurrent Osteomyelitis of the Facial Bones and Calvarium. Journal of Nuclear Medicine, 35(5) (Suppl):113, 1994. Funk GF, Valentino J, McCulloch TM, Graham SM, Hoffman HT. Anomalies of Forearm Vascular Anatomy Encountered During Elevation of the Radial Forearm Flap. Head & Neck, 17(4): 284-292, 1995. Endres D, Manaligod J, Simonson T, Funk GF, McCulloch TM, Hoffman HT. The Role of Magnetic Resonance Angiography in Head and Neck Surgery. Laryngoscope, 105(10):1069-1076, 1995. Weber PC, Seabold JE, Graham SM, Hoffman HT, Simonson TM, Thompson BH. Evaluation of Temporal and Facial Osteomyelitis by Simultaneous In-WBC/Tc-99m-MDP Bone SPECT Scintigraphy and Computed Tomography Scan. Otolaryngology--Head and Neck Surgery, 113(1):36-41, 1995. Seabold JE, Simonson TM, Weber PC, Thompson BH, Harris KG, Rezai K, Madsen MT, Hoffman HT. Cranial Osteomyelitis: Diagnosis and Follow-up with In-111 White Blood Cell and Tc-99m Methylene Diphosphonate Bone SPECT, CT and MR Imaging. Radiology, 196(3):779-788, 1995.



Lebeda MD, Haller JR, Graham SM, Hoffman HT. Evaluation of Maxillary Sinus Aspiration in Patients with Fever of Unknown Origin. Laryngoscope, 105(7 Pt 1):683-685, 1995. (Selected for AAOHNS home study course). Korver KD, Graham SM, Hoffman HT, McCulloch TM, Funk GF. Liver Function Studies in the Assessment of Head and Neck Cancer Patients. Head & Neck, 17(6):531-534, 1995. Bauer CA, Valentino J, Hoffman HT. Long-Term Result of Vocal Cord Augmentation with Autogenous Fat. Annals of Otology, Rhinology, & Laryngology, 104(11):871-874, 1995. Hoffman HT, McCulloch TM. Anatomic Considerations in the Surgical Treatment of Unilateral Laryngeal Paralysis. Head & Neck, 18(2): 174-187, 1996. Redleaf MI, Bauer CA, Gantz BJ, Hoffman HT, McCabe BF. Diatrizoate and Dextran Treatment of Sudden Sensorineural Hearing Loss. American Journal of Otology, 16(3):295-303, 1995. Rassekh CH, Dellspeller KC, Bollen BA, Hoffman HT, Ricks-McGillin J. The QT Interval Following Carotid Artery Resection. Head & Neck, 17(3):242-6, 1995. See WA, Laurenzo JF, Dreicer R, Hoffman HT. Incidence and Management of Testicular Carcinoma Metastatic to the Neck. Journal of Urology, 155(2):590-592, 1996. Valentino J, Funk GF, Hoffman HT, McCulloch TM. The Communicating Vein and Its Use in the Radial Forearm Free Flap. Laryngoscope, 106(5 Pt 1):648-651, 1996. Finnegan EM, Luschei ES, Barkmeier JM, Hoffman HT. Sources of Error in Estimation of Laryngeal Airway Resistance in Persons With Spasmodic Dysphonia. Journal of Speech & Hearing Research, 39(1):105-113, 1996. Clamon GH, Baatz L, Hoffman HT, Hussey DH, Glascock M, McCulloch TM, Graham SM. Neurotoxicity in a Phase I Trial of Continuous-Infusion Cisplatin with Hyperfractionated Radiotherapy for Locally Advanced Head and Neck Cancer. Head & Neck, 18(3):236-241, 1996. Talmi YP, Wolf GT, Hoffman H. Elevated Arginine Vasopressin (AVP) Levels in Squamous Cell Cancer of the Head and Neck. Laryngoscope, 106(3 Pt 1):317-321, 1996. Rubright W.C., Hoffman H.T., Lynch C.F., Kohout F.J., Graham S.M., Funk G.F., McCulloch T.M.: “Risk Factors for Advanced-Stage Oral Cavity Cancer.” Archives of Otolaryngology, 122(6):621-626, 1996. Garvis WJ, Hoffman HT. Hypopharyngeal Dilatation in a Musician. Annals of Otology, Rhinology, & Laryngology, 105(8):669-670, 1996. Smith E, Verdolini K, Gray S, Nichols S, Lemke J, Barkmeier J, Dove H, Hoffman H. Effect of Voice Disorders on Quality of Life. Journal of Medical Speech-Language Pathology, 4(4):223-245, 1996. Devaiah AK, Hoffman HT, Robinson RA, Carter K. Oral Botryomycosis: A Case Report. Journal of Laryngology & Otology, 111(1):77-79, 1997. Hoffman HT, Fischer H, VanDemark D, Peterson KL, McCulloch TM, Funk GF. Botulinum Neurotoxin Injection After Total Laryngectomy. Head & Neck, 19(2):92-92, 1997. (Selected for inclusion in 1998 Year Book of Otolaryngology-Head and Neck Surgery, Mosby). Hoffman TH, McCulloch TM, Gustin D, Karnell LH. Organ Preservation Therapy for Advanced-Stage Laryngeal Carcinoma. Otolaryngologic Clinics of North American, 30(1):113-130, 1997.



Shah JP, Karnell LH, Hoffman HT, Ariyan S, Brown GS, Fee WE, Glass AG, Goepfert H, Ossoff RH, Fremgen A. Patterns of Care for Cancer of the Larynx in the United States. Archives of Otolaryngology, 123(5):475-483, 1997. Brown MR, McCulloch TM, Funk GF, Graham SM, Hoffman HT. Resource Utilization and Patient Morbidity in Head and Neck Reconstruction. Laryngoscope, 107(8):1028-1031, 1997. (Reported in Journal of American College of Surgeons in Advances in Otolaryngology Feb 1998). Karnell MP, Chang A, Smith A, Hoffman H. Impact of Signal Type on Validity of Voice Perturbation Measures. NCVS Status Progress Reports, 11:91-94, 1997. Hoffman HT, Karnell LH, Shah JP, Ariyan S, Brown GS, Fee WE, Glass AG, Goepfert H, Ossoff RH, Fremgen AM. Hypopharyngeal Cancer Patient Care Evaluation. Laryngoscope, 107(8):1005-1017, 1997. Rassekh CH, Dellsperger KC, Hokanson JA, Snyderman CH, Johnson JT, Bollen BA, Hoffman HT. QT Interval Changes Following Neck Dissection: A Stratified Prospective Study. Annals of Otology, Rhinology, & Laryngology, 106(10 Pt 1):869-872, 1997. Zbar RI, Funk GF, McCulloch TM, Graham SM, Hoffman HT. Pectoralis Major Myofascial Flap: A Valuable Tool in Contemporary Head and Neck Reconstruction. Head & Neck, 19(5):412-418, 1997. Johnson RE, Sigman JD, Funk GF, Robinson RA, Hoffman HT. Quantification of Surgical Margin Shrinkage in the Oral Cavity. Head & Neck, 19(4):281-286, 1997. Maschka DA, Bauman NM, McCray PB, Hoffman HT, Karnell MP, Smith RJH. A Classification Scheme for Paradoxical Vocal Cord Motion. Laryngoscope, 107(11 Pt 1):1429-1435, 1997. (Presented at Triologic Society Meeting, Orlando, Florida, May 2-8. 1996). Smith E, Taylor M, Mendoza M, Barkmeier J, Lemke J, Hoffman H. Spasmodic Dysphonia and Vocal Fold Paralysis: Outcomes of Voice Problems on Work-Related Functioning. Journal of Voice, 12(2):223-232, 1998. Victoria LV, Hoffman HT, Robinson RA. Granular Cell Tumour of the Larynx. The Journal of Laryngology & Otology, 112(4):373-376, 1998. McCulloch TM, Hoffman HT. Medialization Laryngoplasty with Expanded Polytetrafluorethylene (ePTFE): Surgical Technique and Preliminary Results. Annals of Otology, Rhinology, & Laryngology, 107(5 Pt 1):427-432, 1998. Jaffe DM, Solomon NP, Robinson RA, Hoffman HT, Luschei ES. Comparison of Concentric Needle Versus Hooked-Wire Electrodes in the Canine Larynx. Otolaryngology--Head & Neck Surgery, 118(5):655-62, 1998. Funk GF, Hoffman HT, Karnell LH, Ricks JM, Zimmerman MB, Corbae DP, Hussey DH, McCulloch TM, Graham SM, Dawson CJ, Means ME, Colwill ML, Titler MG, Smith EM. Cost-Identification Analysis in Oral Cavity Cancer Management. Otolaryngology—Head & Neck Surgery, 118(2):211-220, 1998. Moreano EH, Hutchison JL, McCulloch TM, Graham SM, Funk GF, Hoffman HT. Incidence of Deep Venous Thrombosis and Pulmonary Embolism. Otolaryngology--Head Neck & Surgery, 118(6):777-84, 1998.



Smith EM, Hoffman HT, Summersgill KS, Kirchner HL, Turek LP, Haugen TH. Human Papillomavirus and Risk of Oral Cancer. Laryngoscope, 108(7):1098-1103, 1998. Smith EM, Kirchner HL, Taylor M, Hoffman HT, Lemke J. Voice Problems Among Teachers: Differences by Gender and Teaching Characteristic. Journal of Voice, 12(3):328-334, 1998. Hoffman HT, Karnell LH, Robinson RA, Funk GF, Menck HR. The National Cancer Data Base Report on Cancer of the Head and Neck. Archives of Otolaryngology, 124(9):951-962, 1998. Beatty MM, Funk GF, Karnell LH, Graham SM, McCulloch TM, Hoffman HT. Risk Factors for Malignancy in Adult Tonsils. Head and Neck, 20(5):399-403, 1998. Raab SS, Sigman JD, Hoffman HT. The Utility of Parotid Gland and Level I and II Neck Fine-Needle Aspiration. Archives of Pathology & Laboratory Medicine, 122(9):823-827, 1998. Simplot TC, Hoffman HT. Comparison Between Cartilage and Soft Tissue Ear Piercing Complications. American Journal of Otolaryngology, 19(5):305-309, 1998. (Presented at Fall 1997 AAFPRS Meeting in San Francisco). Talmi YP, Hoffman HT, Horowitz Z, McCulloch TM, Funk GF, Graham SM, Peleg M, Yahalom R, Teicher S, Kronenberg J. Patterns of Metastases to the Upper Jugular Lymph Nodes (The ‘Submuscular Recess’). Head & Neck, 20(8):682-686, 1998. (Presented at the 4th International Conference on Head and Neck Cancer, July 28-August 1, 1996, Toronto, Canada). Graham SM, Hoffman HT, McCulloch TM, Funk GF. Intra-operative Ultrasound-Guided Drainage of Parotid Abscess. Journal of Laryngology & Otology, 112(11):1098-1100, 1998. Smith E, Lemke J, Taylor M, Krichner HL, Hoffman H. Frequency of Voice Problems Among Teachers and Other Occupations. Journal of Voice, 12(4):480-488, 1998. Smith E, Taylor M, Mendoza M, Lemke J, Hoffman H. Functional Impact of Nodules: A Case-Comparison Study. Journal of Voice 12(4):551-558, 1998. Eisele DE, Netterville JL, Hoffman HT, Gantz BJ. Parapharyngeal Space Masses. Head & Neck, 21(2):154-159, 1999. Wellman BJ, Traynelis VC, McCulloch TM, Funk GF, Menezes AH, Hoffman HT. Midline Anterior Craniofacial Approach for Malignancy: Results of En Bloc Versus Piecemeal Resections. Skull Base Surgery, 9(1):41-46, 1999. Victoria L, Graham SM, Karnell MP, Hoffman HT. Vocal Cord Paralysis Secondary to Cardiac Countershock (Cardioversion). Journal of Voice, 13(3):414-416, 1999. Hoffman HT, Karnell LH, Robinson RA, Pinkston JA, Menck HR. National Cancer Data Base Report on Cancer of the Head and Neck: Acinic Cell Carcinoma. Head & Neck, 21(4):297-309, 1999. Karnell LH, Funk GF, Tomblin JB, Hoffman HT. Quality of Life Measurements of Speech in the Head and Neck Cancer Patient Population. Head & Neck, 21(3):229-238, 1999. Beatty MM, Hoffman HT. The Impact of Laryngeal Paralysis and its Treatment on the Glottic Aperture and Upper Airway Flow Characteristics During Exercise. Otolaryngology--Head & Neck Surgery, 120(6):819-823, 1999. (Presented at AAO-HNS Research Forum, September 9, 1997).



Finnegan EM, Luschei ES, Gordon JD, Barkmeier JM, Hoffman HT. Increased Stability of Airflow Following Botulinum Toxin Injection. Laryngoscope, 109(8):1300-1306, 1999. Cody DT, Funk GF, Wagner D, Gidley PW, Graham SM, Hoffman HT. The Use of Granulocyte Colony Stimulating Factor to Promote Wound Healing in Neutropenic Patient After Head and Neck Surgery. Head & Neck, 21(2): 172-175, 1999. Graham SM, McCulloch TM, Funk GF, Hoffman HT. Comment: Recurrent Benign Parotid Tumours: The Lesson Not Learned Yet. Australian & New Zealand Journal of Surgery, 69(7):531, 1999. Finnegan EM, Luschei ES, Hoffman HT. Estimation of Alveolar Pressure During Speech Using Direct Measures of Tracheal Pressure. Journal of Speech Language & Hearing Research, 42(5):1136-1147, 1999. Graham SM, McLennan G, Funk GF, Hoffman HT, McCulloch TM, Cook-Granroth J, Hoffman EA. Preoperative Assessment of Obstruction with Computer Tomography Image Analysis. American Journal of Otolaryngology, 21(4):263-270, 2000. Arnold DJ, Funk GF, Karnell LH, Chen AH, Hoffman HT, Ricks JM, Zimmerman MB, Corbae DP, Zhen W, McCulloch TM, Graham SM. Laryngeal Cancer Cost Analysis: Association of Case-Mix and Treatment Characteristics with Medical Charges. Laryngoscope, 110(1):1-7, 2000. Karnell LH, Funk GF, Hoffman HT. Assessing Head and Neck Cancer Patient Outcome Domains. Head & Neck, 22(1):6-11, 2000. Koch BB, Karnell LH, Hoffman HT, Apostolakis LW, Robinson RA, Zhen W, Menck HR. National Cancer Database Report on Chondrosarcoma of the Head and Neck. Head & Neck, 22(4):408-425, 2000. McCulloch TM, Hoffman HT, Andrews BT, Karnell MP. Arytenoid Adduction Combined With Gore-Tex Medialization Thyroplasty. Laryngoscope 110(8):1306-1311, 2000. Hoffman HT, Quets J, Toshiaki T, Funk GF, McCulloch TM, Graham SM, Robinson RA, Schuster ME, Yuh WT. Functional Magnetic Resonance Imaging Using Iron Oxide Particles in Characterizing Head and Neck Adenopathy. Laryngoscope, 110(9):1425-1430, 2000. Smith EM, Summersgill KF, Allen J, Hoffman HT, McCulloch T, Turek LP, Haugen TH. Human Papillomavirus and Risk of Laryngeal Cancer. Annals of Otology, Rhinology & Laryngology, 109(11):1069-1076, 2000. Finnegan EM, Luschei ES, Hoffman HT. Modulations in Respiratory and Laryngeal Activity Associated with Changes in Vocal Intensity During Speech. Journal of Speech Language & Hearing Research, 43(4):934-950, 2000. Koch BK, Trask DK, Hoffman HT, Karnell LH, Robinson RA, Zhen W, Menck HR. Commission on Cancer. American College of Surgeons. American Cancer Society. National Survey of Head and Neck Verrucous Carcinoma: Patterns of Presentation, Care and Outcome. Cancer, 92(1):110-120, 2001. Simon JH, Zhen W, McCulloch TM, Hoffman HT, Paulino AC, Mayr NA, Buatti JM. Esthesioneuroblastoma: The University of Iowa Experience 1978-1998. Laryngoscope, 111(3):488-493, 2001. Garvey CM, Panje WR, Hoffman HT. The ‘Parachute’ Bolster Technique for Securing Intraoral Skin Grafts. Ear, Nose & Throat Journal, 80(10):720-723, 2001.



Lydiatt WM, Shah JP, Hoffman HT. Head and Neck Sites Task Force. American Joint Committee on Cancer. AJCC Stage Groupings for Head and Neck Cancer: Should We Look at Alternatives? A Report of the Head and Neck Sites Task Force. Head & Neck, 23(8)607-612, 2001. Zhen W, Karnell LH, Funk GF, Enke CA, Hoffman HT. Comparison of Clinical and Pathological Stage for Squamous Cell Carcinoma of the Base of Tongue. Journal of Registry Management, 28(4):177-181, 2001. Lessard JL, Robinson RA, Hoffman HT. Differential Expression of RAS Signal Transduction Mediators in Verrucous and Squamous Cell Carcinomas of the Upper Aerodigestive Tract. Archives of Pathology & Laboratory Medicine, 125(9):1200-1203, 2001. Hoffman HT, Overholt E, Karnell M, McCulloch TM. Vocal Process Granuloma. Head & Neck, 23(12):1061-1074, 2001. Fischer HC, Karnell LH, Hoffman HT, Weining Z, Hartig GK, Robinson RA, McCulloch TM, Menck, HR. A National Survey of Sinonasal Cancer: Presentation, Treatment, and Outcome. Journal of Registry Management, 28(4):182-189, 2001. Lee JH, Barich F, Karnell LH, Robinson RA, Zhen WK, Gantz BJ, Hoffman HT. American College of Surgeons Commission on Cancer. American Cancer Society. “National Cancer Data Base Report on Malignant Paragangliomas of the Head and Neck. Cancer, 94(3):730-737, 2002 Feb. Funk GF, Karnell LH, Robinson RA, Zhen WK, Trask DK, Hoffman HT. Presentation, Treatment and Outcome of Oral Cavity Cancer: A National Cancer Data Base Report. Head & Neck, 24(2):165-180, 2002 Feb. Cooley ML, Hoffman HT, Robinson RA. Discrepancies in Frozen Section Mucosal Margin Tissue in Laryngeal Squamous Cell Carcinoma. Head & Neck, 24(3):262-267, 2002 March. Dutton JM, Graham SM, Hoffman HT. Metastatic Cancer to the Floor of Mouth: The Lingual Lymph Nodes. Head & Neck, 24(4):401-405, 2002 April. Laukkanen A, Titze IR, Finnegan EM, Hoffman H. Laryngeal Muscle Activity in a Tonal Scale: Comparing Speech-like to Song-like Productions in a Mezzo-soprano. Journal of Singing, 59(1):49-56, 2002. McCulloch TM, Andrews BT, Hoffman HT, Graham SM, Karnell MP, Minnick C. Long-Term Follow-Up of Fat Injection Laryngoplasty for Unilateral Vocal Cord Paralysis. Laryngoscope, 112 (7 Pt 1):1235-1238, 2002 July. Van Daele DJ, Finnegan EM, Rodnitzky RL, Zhen W, McCulloch TM, Hoffman HT. Head and Neck Muscle Spasm After Radiotherapy: Management with Botulinum Toxin A Injection. Archives of Otolaryngology, 128(8):956-959, 2002 August. Hoffman H, McCabe D, McCulloch T, Jin SM, Karnell M. Laryngeal Collagen Injection as an Adjunct to Medialization Laryngoplasty. Laryngoscope, 112(8 Pt 1):1407-1413, 2002 August. Maktabi MA, Hoffman H, Funk G, From RP. Laryngeal Trauma During Awake Fiberoptic Intubation. Anesthesia & Analgesia 95(4):1112-1114, 2002 Oct. Heth JA, Funk GF, Karnell LH, McCulloch TM, Traynelis VC, Nerad JA, Smith RB, Graham SM, Hoffman HT. Free Tissue Transfer and Local Flap Complications in Anterior and Anterolateral Skull Base Surgery. Head & Neck, 24(10):901-911, 2002 Oct.



Hoffman HT, Dutton JM, Graham SM. Letter to the Editor. Head and Neck, 25:341-342, February 2003. Ritchie JM, Smith EM, Summergill KF, Hoffman HT, Wang D, Klussmann JP, Turek LP, Haugen TH. Human Papillomavirus Infection as a Prognostic Factor in Carcinomas of the Oral Cavity and Oropharynx. International Journal of Cancer 104:336-344, April 2003. Finnegan EM, Luschei ES, Barkmeier JM, Hoffman HT. Synchrony of laryngeal muscle activity in persons with vocal tremor. Arch Otolaryngol Head Neck Surg, 129(3):313-8, March 2003. Berry DA, Montequin DW, Chan RW, Titze IR, Hoffman HT. An investigation of cricoarytenoid joint mechanics using simulated muscle forces. Journal of Voice, 17(1):47-62, March 2003. Ettema SL, Carothers DG, Hoffman HT. Laryngocele Resection by Combined External and Endoscopic Laser Approach. Annals of Otology, Rhinology & Laryngology, 112(4):361-364, April 2003. Finnegan EM, Luschei ES, Barkmeier JM, Hoffman HT. Synchrony of Laryngeal Muscle Activity in Persons with Vocal Tremor. Archives of Otolaryngology—Head and Neck Surgery, 129:313-318, 2003. Yao M, Buatti J, Dornfeld KJ, Skwarchuk M, Menda Y, Graham MM, Smith RB, Graham SM, Funk GF, Hoffman HT. Is neck dissection necessary when post-radiation PET is negative after radiation treatment for locally advanced head and neck cancer? Int J Radiat Oncol Biol Phys, 1;57(2 Suppl):S244-5, October 2003. Buatti J, Yao M, Dornfeld K, Skwarchuk M, Hoffman HT, Funk GF, Smith RB, Graham SM, Menda Y, Graham MM. Efficacy of IMRT in head and neck cancer as monitored by post-RT PET scans. Int J Radiat Oncol Biol Phys, 1(57)(2 Suppl):S305, October 2003. Smith RB, Apostolakis LW, Karnell LH, Koch BB, Robinson RA, Zhen W, Menck HR, Hoffman HT. National Cancer Data Base Report on Osteosarcoma. Cancer, 98(8):1670-80, October 15, 2003. Smith EM, Ritchie JM, Summersgill KF, Hoffman HT, Wang DH, Haugen TH, Turek LP. Human papillomavirus in oral exfoliated cells and risk of head and neck cancer. J Natl Cancer Inst, 17;96(6):449-55, March 2004. Goldstein DP, Hoffman HT, Hellstein JW, Funk GF. 11 Oral Cavity Lesions. 2 Breast, Skin, Soft Tissue, and Neck. ACS Surgery Online. Souba WW, Fink MP, Jurkovich GJ, et al. Eds. WebMD Inc., New York 2004. http://www.acssurgery/. June 2004. Chao SS, Graham SM, Hoffman HT. Management of pharyngoesophageal spasm with Botox. Otolaryngol Clin North America 37(3):559-66, June 2004. Hoffman HT, Robinson RA, Spiess JL, Buatti J. Update in management of head and neck sarcoma. Current Opinion in Oncology, 16(4):333-341, July 2004. Yao M, Graham MM, Hoffman HT, Smith RB, Funk GF, Graham SM, Dornfeld KJ, Skwarchuk M, Menda Y, Buatti JM. The role of post-radiation therapy FDG PET in prediction of necessity for post-radiation therapy neck dissection in locally advanced head-and-neck squamous cell carcinoma. International Journal Radiat Oncol Biol Phys, 15;59(4):1001-10, Jul 2004. Zhen W, Karnell LH, Hoffman HT, Funk GF, Buatti JM, Menck HR. The National Cancer Data Base Report on Squamous Cell Carcinoma of the Base of Tongue. Head Neck, 26(8):660-74, Aug 2004. Hoffman HT, Buatti J. Update on the Endoscopic Management of Laryngeal Cancer. Current Opinion in Otolaryngology & Head and Neck Surgery, 12(6):525-531, Dec 2004.

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Yao M, Graham MM, Smith RB, Dornfeld KJ, Skwarchuk M, Hoffman HT, Funk GF, Graham SM, Menda Y, Buatti JM. Value of FDG PET in assessment of treatment response and surveillance in head-and-neck cancer patients after intensity modulated radiation treatment: a preliminary report. [Evaluation Studies. Journal Article] International Journal of Radiation Oncology, Biology, Physics, 60(5):1410-8, 2004 Dec 1. Yao M, Buatti JM, Dornfeld KJ, Graham MM, Smith RB, Funk GF, Hoffman HT. Letter. Int. J. Radiat Oncol Biol Phys, 58-697-697, 2004. Yao M, Buatti JM, Dornfeld KJ, Graham MM, Smith RB, Funk GF, Hoffman HT. Can post-RT FDG PET accurately predict the pathologic status in neck dissection after radiation for locally advanced head and neck cancer? In regard to Rogers et al. (Int J Radiat Oncol Biol Phys 2004;58:694-697).[comment]. [Comment. Letter] International Journal of Radiation Oncology, Biology, Physics, 61(1):306-7; Author reply 307, 2005 Jan 1. Kurtz KA, Hoffman HT, Zimmerman MB. Perineural and Vascular Invasion in Oral Cavity Squamous Cell Carcinoma: Increased Incidence on Re-Review of Slides and by Using Immunohistochemical Enhancement. Archives of Pathology and Laboratory Medicine, 129(3):354-9, 2005 Mar. Yao M, Smith RB, Hoffman HT, Funk GF, Graham MM, Buatti JM. Merkel cell carcinoma: two case reports focusing on the role of fluorodeoxyglucose positron emission tomography imaging in staging and surveillance. American Journal of Clinical Oncology, 28(2):205-10, 2005 Apr. McWorter AJ, Hoffman HT. Transoral laser microsurgery for laryngeal malignancies. Curr. Probl Cancer, 29 (4):180-9, 2005 July-August. Yao M, Dornfeld KJ, Buatti JM, Skwarchuk M, Tan H, Nguyen T, Wacha J, Bayouth JE, Funk GF, Smith RB, Graham SM, Chang K, Hoffman HT. Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma--the University of Iowa experience. International Journal of Radiation Oncology, Biology, Physics, 63(2):410-21, 2005 Oct 1. El-Deiry M, Funk GF, Nalwa S, Karnell LH, Smith RB, Buatti JM, Hoffman HT, Clamon GH, Graham SM, Trask DK, Dornfeld KJ, Yao M. Long-term quality of life for surgical and nonsurgical treatment of head and neck cancer. Archives of Otolaryngology -- Head & Neck Surgery,131(10):879-85, 2005 Oct. Yao M, Smith RB, Graham MM, Hoffman HT, Tan H, Funk GF, Graham SM, Chang K, Dornfeld KJ, Menda Y, Buatti JM. The role of FDG PET in management of neck metastasis from head-and-neck cancer after definitive radiation treatment. International Journal of Radiation Oncology, Biology, Physics, 63(4):991-9, 2005 Nov 15. Wemer RD, Lee JH, Hoffman HT, Robinson RA, Smith RJ. Case of progressive dysplasia concomitant with intralesional cidofovir administration for recurrent respiratory papillomatosis.[see comment]. [Case Reports. Annals of Otology, Rhinology & Laryngology, 114(11):836-9, 2005 Nov. Trask DK, Shellenberger DL, Hoffman HT. Transnasal, endoscopic vocal fold augmentation. Laryngoscope, 115(12):2262-5, 2005 Dec. Kurtz KA, Hoffman HT, Zimmerman MB, Robinson RA. Decreased E-cadherin but not beta-catenin expression is associated with vascular invasion and decreased survival in head and neck squamous carcinomas. Otolaryngology - Head & Neck Surgery, 134(1):142-6, 2006 Jan. Andrews BT, McCulloch TM, Funk GF, Graham SM, Hoffman HT. Deltopectoral flap revisited in the microvascular era: a single-institution 10-year experience. Annals of Otology, Rhinology & Laryngology, 115(1):35-40, 2006 Jan.



Guerin LA, Hoffman HT, Zimmerman MB, Robinson RA. Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma. Archives of Pathology & Laboratory Medicine, 130(2):158-64, 2006 Feb. Muirhead DM, Hoffman HT, Robinson RA. Correlation of clinicopathological features with immunohistochemical expression of cell cycle regulatory proteins p16 and retinoblastoma: distinct association with keratinisation and differentiation in oral cavity squamous cell carcinoma. Journal Clin Pathol, 59:711-715, 2006. Yao M, Luo P, Hoffman HT, Chang K, Graham MM, Menda Y, Tan H, Buatti JM. Pathology and FDG PET correlation of residual lymph nodes in head and neck cancer after radiation treatment. Am J Clinical Oncology, 2007 June; 30(3): 264-70. Yao M, Hoffman HT, Chang K, Funk GF, Smith RB, Tan H, Clamon GH, Dornfeld K, Buatti JM. Is planned neck dissection necessary for head and neck cancer after intensity-modulated radiotherapy? Int J Radiat Oncol Biol Phys, 2007 Mar 26. Fuller CD, Wang SJ, Thomas CR Jr, Hoffman HT, Weber RS, Rosenthal DI. Conditional survival in head and neck squamous cell carcinoma: results from the SEER dataset 1973-1998. Cancer, 2007 Apr 1; 109(7):1331-43. Yao M, Nguyen T, Buatti JM, Dornfeld KJ, Tan H, Wacha J, Bayouth JE, Clamon GH, Funk GF, Smith RB, Chang K, Hoffman HT. Changing failure patterns in oropharyngeal squamous cell carcinoma treated with intensity modulated radiotherapy and implications for future research. Am J Clin Oncol, 2006 Dec; 29(6):606-12. Wittkopf J, Connelly S, Hoffman H, Smith R, Robinson R. Infection of true vocal fold cyst with Aspergillus. Otolaryngol Head Neck Surg, 2006 Oct; 135(4):660-1. Hoffman HT, Porter K, Karnell LH, Cooper JS, Weber RS, Langer CJ, Ang KK, Gay G, Stewart A, Robinson RA. Laryngeal cancer in the United States: changes in demographics, patterns of care, and survival. Laryngoscope, 2006 Sep; 116(9 Pt 2 Suppl 111):1-13. Karnell MP, Melton SD, Childes JM, Coleman TC, Dailey SA, Hoffman HT. Reliability of clinician-based (GRBAS and CAPE-V) and patient-based (V-RQOL and IPVI) documentation of voice disorders. J Voice, July 3, 2006. Books/Symposia Iowa Head and Neck Protocols – Surgery, Nursing and Speech Pathology, San Diego: Singular Publishers, Editors: Hoffman H.T., Funk G., McCulloch T.M., Graham S., Dawson C., Fitzpatrick K., and Karnell M, 2000. Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1992 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1993 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1994 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1995 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1996 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1997 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1998 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 1999 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2000

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Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2001 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2002 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2003 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2004 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2005 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2006 Hoffman H.T. (Editor): Iowa Head and Neck Surgery Protocols 2007 Book Chapters Hoffman H, Merkle S, Carey T. Biologic Staging in Head and Neck Cancer: Head and Neck Squamous Carcinoma Cell Lines Capable of Serum Free Growth in Vitro. In Head and Neck Cancer Vol. II, Fee W. (ed). B.C. Decker, Inc., p. 97, 1990. Hoffman HT, Krause CJ. Traumatic Injuries to the Frontal Sinus, Chapter 21. In Oral and Maxillofacial Trauma, Fonseca et al. (eds). W. B. Saunders, Inc., Philadelphia, PA, pp. 576-599, 1990. Hoffman HT. Case Reports in the Management of the Difficult Airway. In Color Atlas of the Difficult Airway at the Time of Anesthesia (segment within a chapter), Fonseca et al. (eds), 1990. Hoffman HT, Eschwege F, Krause C. Combined Surgery and Radiotherapy. In Multimodality Therapy for Head and Neck Cancer, Clark JR, Snow GB. (eds). George Thieme Verlag, Stuttgart/New York, 1992. Funk GF, Hoffman HT, Carter KD. Special Considerations in the Management of Malignant Skin Lesions about the Eye. In Otolaryngologic Clinics of North America: Facial Skin Malignancy II. Vol. 26(2), pp. 215-230, April 1993. Hoffman HT, Gartlan M. Stability of Botulinum Toxin in Clinical Use. In Proceedings of the First International Conference on Botulinum and Tetanus Neurotoxins, Dasgupta B.R. (ed). Plenum Publications, Inc. February, 1993. Traynelis V, McCulloch TM, Hoffman HT. Craniofacial Resection of Neoplasms of the Anterior Skull Base. In Neurosurgical Operative Atlas, Vol. 3 (5), Rengachary SS, Wilkins RH. (eds.). Williams & Wilkins: Baltimore, MD, pp. 329-340, 1993. Hoffman H. Solitary Thyroid Nodule. In Current Therapy in Otolaryngology-Head and Neck Surgery, Gates G., (ed). Mosby-Year Book, Inc., 1994. Funk GF, Valentino J, Graham SJ, Hoffman HT. Hypopharyngeal Reconstruction Using the Radial Forearm Free Flap. In Proceedings of the Second World Congress on Laryngeal Cancer, Smee R, Bridger FP, (eds). Elsevier Science B.V. pp. 749-754, 1994. McCulloch TM, Hoffman HT. Changing Trends in the Treatment of Laryngeal Cancer. In Otolaryngology Head and Neck Surgery, Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Schuller DE. (eds), Update I, 2nd Edition. Mosby-Year Book, Inc: St. Louis, MO, pp. 11-34, 1995. Wagner D, Hoffman HT. Lateral Commissure Repair. In Atlas of Head and Neck Surgery, Bailey BB. (ed), 1995. Hoffman HT, Karnell M. Hoarseness and Laryngitis. In Conn's Current Therapy, Conn HF, Rakel RE. (eds), W.B. Saunders: Philadelphia, PA, pp 28-36, 1996. Graham S, Hoffman HT. Traumatic Injuries to the Frontal Sinus. In Oral and Maxillofacial Trauma, 2nd edition. Fonseca RJ, Walker RV, Betts NJ, Barber HD, (eds). W.B. Saunders Company: Philadelphia, PA, 1996.



McCulloch TM, Jaffe DM, Hoffman HT. Diseases and Operation of Head and Neck Structures Affecting Swallowing. In Deglutition and Its Disorders: Anatomy, Physiology, Clinical Diagnosis, and Management, Chapter 2, Perlman AL, Schulze-Delrieu K, (eds). Singular Publishing Group: San Diego, February, 1997. Hoffman HT, McCulloch TM. Management of Early Glottic Carcinoma. In Otolaryngology--Head and Neck Surgery 3rd ed., Cummings, Fredrickson, Harker, Krause, Richardson, Schuller (eds). Chapter 114 pp 2187-2200, 1998. Hoffman HT, McCulloch TM, Victoria L. Laryngeal Paralysi. In Current Therapy in Otolaryngology-Head and Neck Surgery, 6th Ed. Gates G. (editor). Mosby-Year Book, Inc., January, 1998, pp 84-99. Hoffman HT, McCulloch TM. Botulinum Neurotoxin for TEP Speech Failure. In Tracheoesophageal Voice Restoration Following Total Laryngectomy, Chapter 11, Blom E, Singer MI, Hamaker RC, (eds.), Singular Publishing Group: San Diego, CA, pp. 81-85, 1998. Hoffman HT, Funk G, Endres D. Evaluation and Surgical Treatment of Tumors of the Salivary Glands, Chapter 54 (pp 1147-1182). In Comprehensive Management of Head and Neck Tumors, 2nd ed. 1999. Arnold DJ, Hoffman HT. Assessment and Management of the Unknown Primary with Neck Disease. Chapter 61 pp. 321-328 in Controversies in Otolaryngology published by Theime, Pensack M (ed), 2001. Graham SM, Hoffman HT. Extratemporal Facial Nerve Injury: Avoidance and Pitfalls. Chapter XXIII, pp. 199-208. In Monograph: Update on Facial Nerve Disorders, 1999 Cherry Blossom Conference, Shelton C. (ed), published by the American Academy of Otolaryngology—Head and Neck Surgery Foundation, Inc. Hoffman HT, Overholt EM, Karnell MT, McCulloch TM. Granuloma Contact Ulcers and Other Posterior Lesions. In The Larynx, Ossoff R, Shapshay S, Woodson G, Netterville J, (Eds.). Chapter 20, Lippincott Williams and Wilkins, 2002. Hoffman HT. The Management of Recurrent Laryngeal Nerve Paralysis. In Surgery of the Thyroid and Parathyroid Glands, ed. Randolf G. Boston, Elsevier, 2003. Chao SS, Graham SM, Hoffman HT. Management of Pharyngeal Spasm with Botox, in Otolaryngologic Clinics of North America: Voice Following Laryngeal Cancer Surgery, ed. Deschler DG, 559-566 Philadelphia: Elsevier, 2004. Other Papers Davidson TM, Hoffman HT, Webster RC. Photographic Interpretation of Facial Plastic and Reconstructive Surgery. Journal of Biological Photography 48:87-92, 1980. Hoffman HT. Book Review: The Larynx. In Head and Neck Journal, Harvey T. July/August, 1993. Hoffman HT. Review of Difficulties in Endoscopic Removal of Teflon Granulomas of the Vocal Fold. Otolaryngology Journal Club Journal, 1:30-31, 1994. Hoffman HT. Review of Endoscopic Treatment of Supraglottic and Hypopharyngeal Cancer. Otolaryngology Journal Club Journal 1(4):200-202, 1994. Hoffman HT. Review of Woo et al.: Aerodynamic and Stroboscopic Findings Before and After Microlaryngeal Phonosurgery, from Journal of Voice 1994 8:186-94. Otolaryngology Journal Club Journal 2(3):143-147, 1995.



Hoffman HT, Karnell LH. Laryngeal Cancer. In National Cancer Data Base Annual Review of Patient Care 1995, eds. Steele GD, Jessup JM, Winchester DP, Menck HR, Murphy GP. American Cancer Society, Atlanta, pp 84-99, 1995. Hoffman HT. Review of Brandenburg et al. “Vocal Cord Injection with Autogenous Fat: A Long-Term Magnetic Resonance Imaging Evaluation” from Laryngoscope 1996;106:174-80. Otolaryngology Journal Club Journal 3(5):255-258, 1996. Hoffman HT, McCulloch TM, Gustin D. Organ Preservation Therapy for Advanced Stage Laryngeal Carcinoma. Otolaryngologic Clinics of North America: Current Concepts in Laryngeal Cancer 30( 1):113-130, 1997. Hoffman HT. Book Reviews: Surgery for Cancer of the Larynx and Related Structures, and, Otoneurosurgery and Lateral Skull Base Surgery. Silver C.E. and Ferlito A. (eds); W.B. Saunders, Philadelphia, PA, 1996; in Laryngoscope 107, 1997. Hoffman HT, McCulloch TM. Medialization Laryngoplasty with Gore-Tex, Operative Techniques in Otolaryngology-Head and Neck Surgery 4/99 issue. Maschka DA, Hoffman HT. Paradoxical Vocal Fold Motion: Laryngeal Asthma. Current Opinion in Otolaryngology 7(6), 1999. Karnell LH, Hoffman HT, Smith RB, Robinson RA. Osteosarcoma of the Head and Neck: UIHC Experience Compared to National Data. Abstracts Kambhu S, Clamon G, Doornbos F, Dreicer R, Funk G, Graham S, Hoffman HT, Hussey D, Johnson R, Karwal M, Mayr N, McCulloch T, Riggs C. “Phase II Trial of Taxol and Cisplatin in Advanced Squamous Cell Carcinoma of the Head and Neck.” (Presented at ASCO Annual Meeting, Philadelphia, Pennsylvania, May, 1996.) Summersgill K, Smith E, Hoffman H, Ricks J, Haugen T, Turek L. “Cancer Risk Factors and HPV Frequency in Control and Oral Squamous Cell Carcinoma Patients.” Annual Meeting, AAOMP, Baltimore, Maryland, April 27-May 1, 1996. Summersgill KF, Smith EM, Hoffman HT, Ricks J, Haugen TH, Turek LP. “The Frequency of HPV in the Oral Cavity of a Healthy Adult Population.” 14th International Papillomavirus Conference. Barker JL, Zhen WK, Hoffman HT, McCulloch TM, Buatti JM. “Squamous Cell Carcinoma Metastatic to Cervical Lymph Nodes from Unknown Primary: A Changing Disease.” 2000 ASTRO Meeting. Hoffman HT, Karnell M, McCulloch TM, McCabe D, Jin S. “Transoral Laryngeal Collagen Injection as an Adjunct to Medialization Laryngoplasty.” 2000 Triologic Society Middle Section. McCulloch TM, Andrews BT, Hoffman HT, Graham SM, Karnell MP, Mineck C. “Long-Term Follow-Up of Fat Injection Laryngoplasty for Unilateral Vocal Cord Paralysis.” Submitted 1/02. Littles JF, Karnell LH, Hoffman HT, Menck HR. “Patterns of Treatment by Race and Income for Advanced-Stage Laryngeal Squamous Cell Carcinoma.” Submitted. Finnegan EM, Kochis-Jennings K, Hoffman HT, Titze IR. “Measures of Laryngeal and Respiratory Activity Applied to a Model of Pitch Control.” Submitted.



Grants and Contracts Active - Federal

Co-Investigator, Public Health Service 1 R01 DC04291-01: “The Role of Pressure-Sensitive Reflexes During Phonation” (funding 12/1/99-11/3/03), Eileen M. Finnegan, PhD., PI (10% time; $12,590 salary support).

Co-Investigator, Public Health Service/NIH/NIDR: “HPV Transmission and the Risk of Oral Cancer” (funding 4/1/97-3/31/02), Eileen M. Smith, MPH, PhD, PI (2% time; $740,000).

Co-Investigator, Public Health Service DE13110-01 approved: “Genetic Epidemiology and Mechanisms in Oral Cancer”(funding 9/24/99-8/31/04), Eileen M. Smith, MPH, PhD, PI (3% time; $4,589 salary support).

Consultant, Public Health Service, pending: “RFA on State Models for Oral Cancer Prevention and Early Detection”, Jane Pendergast, P.I.

Research Associate, Public Health Service, 1R01 DC 4681-01 A1: “Medialization Vs. Reinnervation For Vocal Cord Paralysis” (revision submitted 7/2/01; funding 4/1/02-3/31/07). Randal C. Paniello, BS, MS, MD, PI (direct costs $2,173,668, total costs $3,000,826). Consultant, Public Health Service, pending: “Reflexology in Head and Neck Cancer Patients Undergoing Post-Operative Radiation Therapy: A Pilot Study,” Nicole Nisly, P.I.

Invited Lectures and Conference Presentations (*Presenter) *Hoffman HT. “Cancer of the Hypopharynx” presented at conference: “Thoracic Malignancies – Prevention, Early Diagnosis, Treatment” – Friday, March 12, 1999 Iowa City. *Hoffman HT, Karnell LH, Robinson RA, Funk GF, Menck HR. The National Cancer Data Base Report on Cancer of the Head and Neck” presented (poster) American Society of Head and Neck Surgery May 14-15, 1998 Palm Beach, Florida. *Hoffman HT. “Comprehensive Review of Laryngology.” Iowa Speech-Language Hearing Association October 25, 1996 Hotel Fort Des Moines; Des Moines Iowa.

*Graham SM, Funk GF, Hoffman HT, McCulloch TM, Robinson RA. “Perineural Invasion and Tumor Necrosis are Histological Predictors of Poor Clinical Outcome in Acinic Cell Carcinoma.” Middle Section Triologic Society January 26, 1997 Kansas City, Missouri. *Hoffman HT, et al. “Hypopharyngeal Patient Care Evaluation.” Western Section of the Triologic Society. Tucson Arizona. January 8, 1997. *Hoffman HT,, et al. "Calcium Dependent Regulation of Cell Surface Antigen Expression on Normal and Malignant Human Squamous Cells in Vitro." Second International Conference on Head and Neck Cancer, Boston, Massachusetts. July 31, 1988. *Hoffman HT, et al. "Head and Neck Squamous Carcinoma Cell Lines Capable of Serum-Free Growth in Vitro.” Second International Conference on Head and Neck Cancer Boston, Massachusetts. July 31, 1988. *Hoffman HT, et al. "Epidermal Growth Factor Induced Inhibition of Squamous Cell Carcinoma Proliferation is Correlated with Loss of Cell Surface Epidermal Growth Factor Receptor Expression." AAOHNS Meeting Washington, D.C. September, 1988.



*Hoffman HT, et al. "Magnetic Resonance Imaging in the Evaluation of Mucoceles of the Ethmoid Sinus." AAOHNS Meeting Washington, D.C. September, 1988. *Hoffman HT. "The Difficult Airway Symposium.” Department of Anesthesiology, University of Michigan. November 14, 1988. *Hoffman HT, et al. "Laryngeal Framework Surgery in the Treatment of Glottic Insufficiency: Modifications in Technique." Western Section Meeting of the Triologic Society, Monterey, California. January 6, 1990. *Hoffman HT, et al. "Arytenoid Subluxation: Diagnosis and Treatment." American Laryngological Association Meeting Palm Beach, Florida. April 29, 1990. *Robbins KT, Storniolo AM, Hoffman HT, Hoffman RM. "Drug Response of Head and neck Tumors in Native State Histoculture." ASHNS, Palm Beach, Florida. April 30, 1990. *Hoffman HT, et al. "Mandible Reconstruction with Vascularized Bone: Histomorphology of Bone Union." ASHNS Meeting, Palm Beach, Florida. April 30, 1990. *Bunge R, Sullivan M, Hoffman H, Ridley M. "Lip Splitting Incisions: A Critical Evaluation of Cosmetic Results". AAFPRS San Diego, California September, 1990. *Wright D, Hoffman HT, Hoyt D. "Frontal Sinus Fractures in the Pediatric Population." Western Section of the Triologic Society, Santa Barbara, California, January 21, 1991. *Hoffman HT, Jalowayski AA, Robbins KT, Feldman J. "Floor of Nose and Palate Reconstruction with Local Mucoperiosteal Flaps and Latissimus Dorsi Free Flap." Western Section of AAFPRS San Francisco, California, February 1, 1991. *Hoffman HT. "Phonosurgery." Iowa Medical Society, Des Moines, Iowa April 19, 1991. *Hoffman HT. "Mandibular Continuity Defects: Vascularized vs. Conventional Bone Grafts." To Department of Oral Surgery, University of Iowa Hospitals and Clinics, April 26, 1991. *Hoffman HT. "Reconstructive Surgery Utilizing Free Flaps" and "Head and Neck Resections/Case Presentations." Eighth Annual Iowa Head and Neck Cancer and Reconstructive Surgery Course for Nurses. May 20, 1991. Frodel JL, Capper DT, *Funk GF, Fridrich KL, Blumer JR, Haller JR, Hoffman HT. "Osseointegrated Implants in Vascularized Bone Flaps: A Comparison of Bone Thickness in Four Bone Flap Types Used in Mandibular Reconstruction." Presented at the 1991 AAFPRS Annual Meeting. *Yuh WTC, Ryals TJ, Farrar GR, Rezai K, Hoffman HT. "Gadolinium-Enhanced MRI in the Evaluation of Post-Balloon Carotid Test Occlusion Patient: Preliminary Result." Presented at the 29th Annual Meeting of the American Society of Neuro Radiology June 11, 1991, Washington D.C. *Hoffman HT. "Head and Neck Reconstruction." Presented at SOHN, Kansas City, Kansas. September 21, 1991. Bauman N, *Graham S, Hoffman H. "Hormonal Receptors in Adenoid Cystic Carcinoma." Presented at Southern Section of Triologic Society. Sea Island, Georgia. January 17, 1992. *Maschka D, Hoffman H, Bottles K. "Mucoepidermoid Carcinoma, A Three Tiered Staging System." Presented at the Middle Section of the Triologic. Cleveland, Ohio. January 24, 1992.



*Peterson KL, Hoffman HT, VanDemark D, Barkmeier JM. “Botulinum Neurotoxin A Injection to the Pharyngeal Constrictor Muscles After Total Laryngectomy." Presented at the Southern Section of the Triologic Society Sea Island, GA. January 17, 1992. *Gartlan MG, Peterson KL, Hoffman HT, Luschei ES, Smith RJH. "The Bipolar Hooked-Wire Electromyographic Technique in the Evaluation of Pediatric Vocal Cord Paralysis.” ASPO, Palm Desert, California. April, 1992. *Rassekh C, Hoffman HT, Bolin B. "The Q T Interval Following Carotid Artery Resection." Triologic, Palm Desert California. April, 1992. *Peterson KL, Verdolini-Marsten K, Barkmeier J, Hoffman HT. "Correlation of Electroglottography with Aerodynamic Parameters in Evaluating Voicing Patterns." ALA, Palm Desert, California. April, 1992. *Redleaf MI, Bauer CA, Gantz BJ, Hoffman HT, McCabe BF. "Diatrizoate and Dextran Therapy of Sudden Sensorineural Hearing Loss." AOS, Palm Desert, California. April, 1992. *Finnegan EM, Luschei ES, Hoffman HT. “Modulation of Laryngeal EMG and Subglottic Pressure Associated with Intensity Changes During Speech.” Poster presented at the First International Neurolaryngology Symposium, Bethesda, Maryland. October 1996. *Finnegan EM, Luschei ES, Gorden J, Barkmeier JM, Hoffman HT. “Increased Stability of Airflow Following Botulinum Toxin Injection.” Poster session presented at the Speech Motor Control Conference, Amelia Island, Florida. February 1996. *Finnegan EM, Luschei ES, Hoffman HT. “Analysis of EMG of Intrinsic and Extrinsic Laryngeal Muscles in Persons with Vocal Tremor.” Presented at the Annual Voice Foundation Meeting, Philadelphia, Pennsylvania. June 1995. Peterson KL, Verdolini K, Barkmeier J, Hoffman HT. “Comparison of Aerodynamic and Electroglottographic Parameters in Evaluating Clinically Relevant Voicing Patterns.” 1992 NCVS Annual Conference. January 14, 1993. Smith E, Nichols S, Lemke J, Verdolini K, Barkmeier J, Dove H, Hoffman H. “Effects of Voice Problems on Patients; Work, Social, and Family Interactions, and Self-Esteem: Preliminary Results.” Min Y, Luschei E, McCulloch T, Barkmeier J, Hoffman H. “Quantitative Analysis of EMG Waveform in Laryngeal Paralysis.” *Hoffman HT, Graham SM, McCulloch TM, Funk GF, Morris H. "Laryngeal Fat Injection." National Voice and Speech Center Meeting, Iowa City, Iowa, January 15, 1993. Barkmeier J, Hoffman HT, Morris H. “Update on Extralaryngeal Botulinum Injection for Hyperkinetic Voicing.” Blumin J, Barkmeier J, Hoffman H. “Aerodynamic Measures During Voicing; A Novel Approach to Characterizing Results.” Verdolini K, Hoffman HT. “Speech Pathology Considerations in the Treatment of Vocal Process Granuloma.”



*Barkmeier JM, Hoffman HT, Runner SJ, Herwig SR. "The Newlyweds: Otolaryngology and Speech

Pathology - A team Approach to Videoendoscopy." ASHA Annual Convention, Anaheim, California. November 1993.

McCulloch TM, Funk GF, Hoffman HT, Graham SM. "Mandibular Replacement Using Osseointegrated Mandibular Reconstruction Plates." 1st International Congress on Maxillofacial Prosthetics, Indian Wells,

California. April 1994. Smith E, *Taylor M, Mendoza M, Lemke J, Hoffman H. “Functional Impact of Nodules: A Case-Comparison Study.” Presented at 24th Annual Voice Foundation, Philadelphia, Pennsylvania. June 5-10, 1995

Hoffman H. “Vocal Cord Paralysis/Laryngeal Dysfunction”. Presented at Second Annual Otorhinolaryngology Update.” Saturday, May 3, 1997. University of Toronto: Mt. Sinai Hospital 10th Annual Head and Neck Oncology Lecture “Head and Neck Cancer in the United States.” October 27,1998. Visiting Professor Grand Rounds: “Laryngeal Paralysis.” October 28,1998. Fourth International Head and Neck Cancer Conference, Toronto Canada. “Hypopharyngeal Cancer: Long Term Outcome and Strategies to Improve.” July 28, 1996. Fourth International Head and Neck Cancer Conference, Toronto Canada. “Squamous Cell Carcinoma of the Hypopharynx: Strategies for a Successful Outcome.” July 28,1996. Mainz Germany, visiting professor. “Survey of Laryngeal Cancer in the United States.” July 1, 1996. University of Gottingen, Germany: Up-to-date Report of Head & Neck Surgery in the USA Workshop, June 29, 1996, “Laryngeal Cancer in the U.S.: A Review of 17,240 Cases.” Alberta Society of Otolaryngology Annual Meeting. "Arytenoid Adduction", "Surgical Margins in Head and Neck Cancer Resection", "Surgical Treatment of Aspiration." March 17-19th 1995. Pan-American Otolaryngology Conference, Margarita Island, Venezuela: "Laryngology Panel: Treatment of Laryngeal Paralysis", November 5, 1994. Craniofacial Rehabilitation and Osseointegration in the Oncology Patient, Ottawa, Canada : "Anterior Skull Base and Midface Reconstruction" and "Lateral Skull Base Reconstruction," September 17, 1993. Australia Academy of Otolaryngology Head and Neck Surgery, Adelaide, Australia, Keynote Speaker: "Contemporary Assessment of Vocal Dysfunction." Additional topics: "Botulinum Toxin and the Treatment of Swallowing and Speech Disorders"/"Surgical Options in the Aspirating Patient"/"Management of Bilateral Fixed Vocal Cords"/"Reconstruction Following Upper Jaw Resection"/"Frontal Sinus Fractures"/"Osseointegration and the Otolaryngologist," March, 1993. Christchurch, New Zealand, Public Hospital: "Contemporary Assessment of Vocal Dysfunction"; Otolaryngology Department: "Contemporary Treatment of Unilateral Vocal Cord Paralysis"/"Surgical Options in the Aspirating Patient," March 16, 1993. Grand Rounds, Christchurch, New Zealand: "Botulinum Toxin in the Treatment of Speech and Swallowing Disorders," March 17, 1993. First International Conference of Botulinum and Tetanus Neurotoxins, Madison, Wisconsin: "Degradation of Botulinum Neurotoxin A with Storage,” May 1992.



Second International Conference on Head and Neck Cancer, Boston, Massachusetts: "Biologic Staging of Head and Neck Cancer," July 1988. Invited Lectures and Papers 1988 Lecturer, University of Michigan Medical and Dental Schools, Ann Arbor, MI 1989 Instructor, University of California, San Diego, School of Medicine, San Diego, CA Embryology of the Head and Neck Core Anatomy Course Lecturer, University of Michigan Medical and Dental Schools, Ann Arbor, MI American Academy of Facial Plastic and Reconstruction Surgery Sponsored Courses, Ann Arbor, MI “Microvascular Reconstruction of the Head and Neck,” 3/89 1990 Director, University of Iowa Head and Neck Surgery Fellowship, Iowa City, IA Co-Director and Lecturer, Maxillofacial Bone Plating Symposium, San Diego, CA, 2/90 American Academy of Facial Plastic and Reconstruction Surgery Sponsored Courses, Iowa City, IA “Craniofacial Maxillofacial Rigid Internal Fixation Workshop,” 10/25-27 Director, University of California, San Diego, Head and Neck Surgery Weekly Lecture Series, 1/90-7/90 1991 Director, University of Iowa Head and Neck Surgery Fellowship, Iowa City, IA Co-Director, National Center for Voice Laryngology Fellowship, Iowa City, IA American Academy of Facial Plastic and Reconstructive Surgery Advanced Soft Tissue Workshop, Cincinnati, OH “Lip Reconstruction,” 1/15 1992 Director, University of Iowa Head and Neck Surgery Fellowship, Iowa City, IA Co-Director, National Center for Voice Laryngology Fellowship, Iowa City, IA Vanderbilt University Phonosurgery Tutorial and Hands-on Workshop, Nashville, TN, 11/6-7, 1 hr ea “Thyroplasty,” “Arytenoid Adduction,” “Complications” AAO-HNS Annual Meeting Instruction Course, Washington, DC, 9/30, 1 hr “Laryngeal EMG” University of Wisconsin Phonosurgery Symposium, Madison, WI, 7/17 “Indications for Phonosurgery,” “Extralaryngeal Botox Injection.” Voice Disorders: Current Status of Diagnosis and Treatment, Sacramento, CA, 2/21 “Laryngeal EMG,” “Arytenoid Adduction,” “Botulinum Toxin in Speech and Swallowing Disorders,” Panel Discussion. American Academy of Facial Plastic and Reconstructive Surgery Advanced Soft Tissue Workshop, Chicago, IL “Blood Flow in Head and Neck Reconstruction,” 1/16 American College of Surgeons, Iowa Chapter, Surgery Postgraduate Conference, 11/13 “Conservative Laryngeal Surgery and Phonosurgery” 1993 Director, University of Iowa Head and Neck Surgery Fellowship, Iowa City, IA Co-Director, National Center for Voice Laryngology Fellowship, Iowa City, IA Vanderbilt University Phonosurgery Tutorial and Hands-on Workshop, Nashville, TN, 10/22-23, 1 hr ea “Arytenoid Adduction,” “Laryngeal Fat Injection” AAO-HNS Annual Meeting Instruction Course, Minneapolis, MN, 10/4, 1 hr “Laryngeal EMG” American College of Surgeons, University of California, San Francisco, Head and Neck Surgery



Workshop, San Francisco, CA, 10/10, “Laryngeal Cancer” Keynote Speaker, Wisconsin State Otolaryngology Society, Green Lake, WI “Laryngeal Paralysis,” 10/16 “Voice Evaluation and Indications for Phonosurgery,” 10/17 1994 Director, University of Iowa Head and Neck Surgery Fellowship, Iowa City, IA Co-Director, National Center for Voice Laryngology Fellowship, Iowa City, IA Vanderbilt University Phonosurgery Tutorial and Hands-on Workshop, Nashville, TN, 10/28-29 “Evaluation of Laryngeal Paralysis,” “Injection Laryngoplasty,” “Arytenoid Adduction” AAO-HNS Annual Meeting Instruction Course, San Diego, CA 9/16-19 University of Wisconsin Phonosurgery Symposium, Madison, WI, 7/15-17 “Spasmodic Dysphonia” SHNS/ASHNS Workshop Speaker, Chicago, IL, 10/9 “Tumors of Paranasal Sinus” Invited Speaker, American Academy of Maxillofacial Prosthetics, New Orleans, LA, 11/2 “Surgical Aspects of Extraoral Implants” Invited Panelist, Phonosurgery Symposium, XXIV Pan-American Congress of Otorhinolaryngology and Head and Neck Surgery, Margarita Island, Venezuela, 11/4 Invited Speaker, Kansas City Society of Ophthalmology and Otolaryngology, Kansas City, MO, 12/9 “Laryngeal Cancer” 1995 Co-Director, National Center for Voice Laryngology Fellowship, Iowa City, IA AAO-HNS Annual Meeting Instruction Course, New Orleans, LA, 9/17-20, 2 hrs “Interactive Laryngologist Workshops” Invited Speaker, Alberta Society of Otolaryngology and Head & Neck Surgery, Lake Louise, Alberta, Canada, 3/17/19, “Surgical Treatment of Aspiration” Invited Panelist, 1st Work Voice Conference, Oporto, Portugal, 4/9-13 Visiting Professor, MD Anderson Cancer Center, Houston, TX, 5/9-10 “Surgical Treatment of Aspiration,” “Innovations Regarding Voice” 1996 Co-Director, National Center for Voice Laryngology Fellowship, Iowa City, IA AAO-HNS Annual Meeting Instruction Courses, Washington, DC, 2 hrs “Interactive Laryngology Workshops” University of Wisconsin Phonosurgery Symposium, Madison, WI, 7/12-13 “Minimally Altered Vocal Fold Tissues: Assessment and Phonosurgical Management of Benign VC Lesions” “Arytenoid Adduction Workshop,” “Surgical Management of Laryngeal Trauma” BFM-ORL Meeting, South Carolina, 6/13-16 “Laryngeal Cancer in the United States,” “Organ Preservation in Laryngeal Cancer” 11th Annual Jack Hough Lectureship: The Art and Science of Voice Care, Oklahoma City, OK, 11/16 “Anatomic Considerations in Vocal Fold Medialization and Vocal Fold Paralysis,” “Update on Laryngeal Cancer”, “Computer Assisted Interactive Session on Phonosurgery and Laryngeal Disorders” 7th Annual Cancer Symposium, Fargo, ND, 10/18-19 “Treatment of Common Voice Disorders,” “Cancer of the Larynx,” “Management of Swallowing Disorders” Iowa Speech and Hearing Association Lectures, Des Moines, IA, 10/25, 3.5 lectures



1997 AAO-HNS Annual Meeting Instruction Course, San Francisco, CA, 2 hrs “Interactive Laryngology Workshops” Visiting Professor, University of Cincinnati, Cincinnati, OH, 1/10-11 Resident Tutorial: “Thyroid Cancer,” Ground Rounds: “ “Standard of Care for Laryngeal and Hypopharyngeal Cancer,” Cincinnati Otolaryngology Society: “Laryngeal Paralysis” Summer Update in Otolaryngology, University of Wisconsin, Beaver Creek, CO, 7/26-30 “Endoscopic Laser Surgery for Laryngeal Cancer,” “Overview of Salivary Gland Tumors” Visiting Professor, Stanford University, Stanford, CA, 10/7-8 Grand Rounds (Joint Stanford and UCSF programs): “Salivary Gland Tumors” Invited Speaker, American College of Surgeons 83rd Annual Clinical Congress, Chicago, IL, 10/13-14 “Surgical Treatment of Cancer of the Oral Cavity,” “Medialization Laryngoplasty” Visiting Professor, University of Wisconsin, Madison, WI, 11/1 “Grand Rounds: “Oral Cavity Cancer” Visiting Professor, University of Minnesota, Minneapolis, MN, 12/1 Grand Rounds: “Salivary Gland Neoplasms,” Resident Rounds: “Laryngeal Paralysis” 1998 AAO-HNS Annual Meeting Instruction Course, San Antonio, TX “Interactive Laryngology Workshops,” 2 hrs “Simplified Type I Thyroplasty Utilizing a Gore-Tex Implant”, 1 hr University of Wisconsin Phonosurgery Symposium, Madison, WI, 7/10 “Update on Endoscopic Microsurgery” How I Do It,” “Bringing Them Together: Gore-Tex thyroplasty and Arytenoid Adduction as Treatments of Glottic Incompetence,” “Techniques: How I Did It and Wished I Didn’t” Invited Faculty, University of Pennsylvania, Contemporary Concepts in Laryngeal Surgery for Benign and Malignant Disease, Pittsburgh, PA, 3/98 “Open Techniques of Vocal Cord Medialization: “Gore-Tex Technique”, Panel: “Rehabilitation of the Paralyzed Larynx,” Panel: “Laryngeal and Pharyngeal Cancer,” “Tracheoesophageal Puncture for Voice Rehabilitation: Botox Injections for Pharyngeal Spasm” Invited Faculty, Pacific Voice Conference, San Francisco, CA, 11/7 “Gore-Tex Thyroplasty: The Need for a Collaborative Approach” Invited Faculty, Memorial Sloan-Kettering Cancer Center, Current Concepts in Head and Neck Surgery, New York, NY, 11/14-15 “Management of Early Laryngeal Cancer”, “Management of Oral Cavity Cancer”, “Maxillectomy,” Panel Moderator: “Thyroid Cancer,” “Skull Base Cancer” 1999 Invited Faculty, Combined Otolaryngology Spring Meeting (COSM), Palm Desert, CA, 4/24-5/1 Invited Faculty, Pacific Coast Oto-Ophthalmological Society (PCOOS), Victoria, British Columbia, 6/19-23 “Contemporary Management of the Paralyzed Chord,” “Update on the Management of Head and Neck Cancer” Visiting Professor, University of New Mexico, 7/25/99, “Laryngeal Paralysis” Invited Panelist, AAO-HNS Annual Meeting, New Orleans, LA, 9/25-29/99, “Update on Laryngology,” “Simplified Type I Thyroplasty Employing Gore-Tex Implant, “Clinical Utility of Laryngeal EMG” Invited Faculty, Iowa Speech Association Meeting, Des Moines, IA, 10/22-23/99 Visiting Professor, University of Utah, Salt Lake City, UT, 10/28-31/99 2000 Invited Faculty, International Head and Neck Oncology Research Group (IHNORG) Inaugural Meeting, Oklahoma City, OK, 1/6-8 Invited Faculty, Western Section Meeting of the Triologic Society, San Francisco, CA, 1/8-11/00 “Functional MR Imaging Using Iron Oxide Particles in Characterizing Head and Neck Adenopathy”



Visiting Professor, University of Arizona, Tucson, AZ, 1/14-17 Invited Lecturer, 69th Midwinter Clinical Conference, Research Study Club of Los Angeles, Los Angeles, CA, 1/28-30 Invited Faculty, 22nd Annual Sisson Head and Neck Workshop, Vail, CO, 2/2-4 “Laryngology Update” Invited Member, Ad Hoc NIH Study Section for Behavioral and Biobehavioral Processes (BBBP-7), Washington, DC, 2/16 Visiting Professor, Assistance Hopitaux Publique ed Paris Laennec, Paris, France, 3/14-17 Invited Lecturer, Soeiete de Laryngologie Des Hopitaux de Paris, Paris, France, 3/17 “Thyroplasty with ePTFE (Gore-Tex)” Foundations of Clinic Practice Lecture Schedule to second-year medical students at University of Iowa, Med Alumni Auditorium, UIHC, Iowa City, IA Iowa Academy of Otolaryngology Annual Meeting, Jointly Sponsored by the Iowa Medical Society and The University of Iowa College of Medicine, Des Moines, IA, 4/15 State Chair Position Orientation Meeting, Commission on Cancer, College of Surgeons, Washington, DC, 4/27-30 Invited Lecturer, 5th Annual Otorhinolaryngology Update, Department of Nursing, UIHC, Iowa City, IA, 4/18 Guest Faculty, 6th Biennial Phonosurgery Symposium, University of Wisconsin, Madison, WI, 7/14-15 “Poor Results in Surgery for Laryngeal Paralysis: Panel Presentations and Discussion”, “When and How to Treat Reflux”, “Basic Concept and Technique of Arytenoid Adduction”, “Laryngeal Applications for Mitomycin-C, Cidofovir, and Collagen” Instructor, Conference on Head and Neck Cancer, San Francisco, CA, 7/28-8/3 Invited Panelist, AAO-HNS Annual Meeting, Washington, DC, 9/23-9/26 Guest Lecturer, Mercy Medical Center Grand Rounds, Sioux City, IA, 9/29 Invited Panelist, AHNS Fall Council Meeting and Retreat, Chicago, IL, 10/20 Invited Panelist, AJCC Head and Neck Task Force Meeting, Chicago, IL 10/21 Invited Lecturer, 42nd Annual ASTRO Meeting, Boston, MA, 10/22 Invited Lecturer, American College of Surgeons Meeting, Chicago, IL 10/23-10/27 Visiting Professor, University of North Carolina/Bowman-Gray, Winston-Salem/Chapel Hill, NC, 11/15-11/19 Invited Panelist, Semiannual ASOSOG Meeting, 12/1-12/2 2001 Invited Lecturer, Middle Section Triologic Meeting, Chicago, IL, 1/19-1/21 Invited Panelist, Sisson Workshop, Vail, CO, 2/6-2/10 “Advanced Cancer: We Have Failed, What’s Next, Bench to Bedside, Early Trials with Great Potential” Invited Lecturer, 29th Annual Spring Meeting, American College of Surgeons, Toronto, ON 4/22-25 State Chair Meeting, Commission on Cancer Guest Speaker, UCSD Otolaryngology Graduation, San Diego CA, 6/21-24 Invited Lecturer, Royal Society-AAO/HNS Meeting, Saint Andrews, Scotland, 7/11-14 “Laryngeal Airway Compromise Problems: Paradoxical Vocal Fold Motion; Bilateral and Unilateral Vocal Fold Immobility” Committee Member, Comprehensive Cancer Control Study, Department of Public Health, State of Iowa, Des Moines, IA 8/17/01 HNS & Oncology Committee Member, AAO-HNS Annual Meeting, Denver, CO, 9/9-9/12/01 Invited Lecturer, Postgraduate Course, American College of Surgeons, Annual Clinical Congress, New Orleans,

LA, 10/7-10/12/01, “Surgical Treatment of Cancer of the Oral Cavity”



Invited Lecturer, Harvard CME Course, Surgeon of the Thyroid and Parathyroid Glands, Boston, MA 11/9-10/01 “Vocal Cord Paralysis: Diagnosis and Repair” Invited Lecturer, Department of Anesthesia, UIHC, Iowa City, IA 12/11/01 “Airway Anatomy and Science” 2002 Visiting Professor, Department of Otolaryngology, University of Florida, Gainesville, FL, 1/6-7/02 “Head and Neck Cancer Cases” Invited Lecturer, Triologic Society Middle Section Meeting, Oklahoma City, OK, 1/18-20/02 “Vocal Cord Paralysis Alternatives for Early Intervention” “The Deltopectoral Flap Revisited in the Microvascular Era: A Single Institution’s 10 Year Experience” Invited Panelist, Sisson Workshop, Vail, CO, 2/9-16/02 “Treatment Updates for Benign Laryngeal Disease” Invited Lecturer, Update in Otolaryngology, Scottsdale, AZ, 2/02 Invited Lecturer, Combined Iowa/Mt. Sinai Head and Neck Course, New York, NY, 3/6-11/02 Invited Lecturer, Australian Society of Otolaryngology—Head and Neck Surgery, Adelaide, Australia, 5/7-20/02 Invited Lecturer, Phonosurgery Symposium, Madison, WI, 7/11-14/02 Panel Member, Eleventh Annual Dysphagia Research Society Meeting, Miami, FL, 10/3-5/02 “Topics: Aspiration Risks and Treatment in Vocal Cord Paralysis; Future of Implants: Neurophysiology, Long Term Effects, and Limitations; and Tracheo-Esophageal Separation Procedures” Participant, Training Course for Protocol Z0360: Sentinel Node Biopsy in Head and Neck Surgery, American College of Surgeons Oncology Group, Miami, FL, 10/25-27 2003 Invited Speaker, San Diego Academy of Otolaryngology—Head and Neck Surgery, “An Update in Laryngology”, La Jolla, CA, 2/13 Invited Speaker, American Cancer Society Meeting, 2/14/03 Invited Speaker, 2003 Annual Head and Neck Surgery Symposium, Southern California Permanente Medical Group, Anaheim, CA, 2/15 “Swallowing Disorders” and “The Uses of Botox in Otolaryngology” Board Examiner, 2003 Oral Examination, American Board of Otolaryngology, 4/26 2004 Invited Speaker, “9th Workshop on Laser Voice Surgery,” Paris, France, 4/15-18/2004. Invited Speaker, “Voice and Swallow Symposium,” Seattle, Washington, 8/27-8/28/2004. “Transnasal Esophagoscopy: Equipment Needs, Methods, Pittfalls.” Invited Speaker, “VA Fall Symposium,” 10/7/2004. “Hoarseness.” 2006 Invited Speaker, “Dysphagia Research Society Meeting,” Scottsdale, Arizona, 3/22-25/2006. “Current Trends in Head and Neck Cancer Treatment.” Pending Decisions Victoria L.V., Hoffman H.T., and McCulloch T.M.: “Paralisis de cuerdas vocales diagnostico y manejo actual” accepted with revision 11/97 (published).



Finnegan E.M., Luschei E.S., and Hoffman H.T.: “Calculation of Alveolar Pressure During Speech Using Direct Measures of Tracheal Pressure” submitted. Andrews B., McCulloch T., Hoffman H., Funk G., Graham S., and Browning M.: “Uses of Deltopectoral Flap in the 1990s” submitted. (Presented at 5th International Conference on Head and Neck Cancer, San Francisco, California, July, 2000). Finnegan E.M. and Hoffman H.T.: Letter to the Editor, “Response to Drs. Zajac and Warren” submitted to American Speech-Language-Hearing Association in 9/00. Wittkopf J., Connelly S., Hoffman H., Smith R., and Robinson R.: “Infection of True Vocal Fold Cyst with Aspergillus” submitted to Otolaryngology—Head and Neck Surgery in 9/01; revision letter sent to us 5/10/02 and forwarded to Justin Wittkopf; revision fax sent to us and forwarded to Justin Wittkopf 4/4/03. Berry D.A., Montequin D.W., Chan R.W., Titze I.R., and Hoffman H.T.: “An Investigation of Cricoarytenoid Joint Mechanics Using Simulated Muscle Forces” accepted in Journal of Voice 10/01. Lydiatt W.M., Hoffman H.T., and Shah J.P.: Letter to the Editor, “Response to the Letter to the Editor” submitted to Head and Neck in 12/01. Fischer H., Karnell L., McCulloch T., Hoffman H., Hartig G., Zhen W., and Robinson R.: “The National Cancer Data Base Report on Esthesioneuroblastoma” in preparation. Zhen W., Karnell L., Hoffman H., Funk G., Buatti J., and Menck H.: “The National Cancer Data Base Report on Cancer of the Head and Neck: Squamous Cell Carcinoma of the Base of the Tongue” in preparation. Finnegan E.M., Luschei E.S., Barkmeier, J.M., and Hoffman H.T.: “Intrinsic and Extrinsic Laryngeal Muscle Activity in Persons with Vocal Tremor” in preparation. Barker J.L., Paulino A.C., Feeney S., McCulloch T., and Hoffman T.: “Locoregional Treatment for Adult Soft Tissue Sarcomas of the Head and Neck—An Institutional Review” in preparation. IV. SERVICE Professional Offices Fellow, American College of Surgeons Fellow, American Academy of Otolaryngology, Head and Neck Surgery American Medical Association American Society for Head and Neck Surgery American Broncho-Esophagological Association Investigator, National Center for Voice and Speech, The University of Iowa, 1990-present American Broncho-Esophagalgia Association Active Member, October 1998 State Chair, Commission on Cancer, American College of Surgeons Appointed, November 1999 Edinburgh Voice Centre, Edinburgh, Scotland Scientific and Medical Advisor, February 2000-present Executive Counsel of the American Head and Neck Society, 2001 Secretary, Advanced Training Council for Head and Neck Surgery, May 2002 Commission on Cancer, 2002 American Laryngologic Society, May 2007 Editorial Activities



Associate Editor, Head and Neck Surgery, July 1994 to 2003 Expert Analyst for Otolaryngology: The Journal Club Journal, November 1993-1998 Editorial Board for Online Journal of Head and Neck Surgery and Oncology, January 1, 2004- present Ad hoc Journal Reviews Head &Neck, December 1989-present Annals of Otology, Rhinology & Laryngology, September 1990-present Otolaryngology--Head & Neck Surgery, October 1994-present Laryngoscope, July 1996-present Anesthesiology, August 1996-present Cancer, December 1996-present Service on Collegiate, University, University Hospitals and National Committees American Society for Head and Neck Surgery Scientific Program Committee, 1997-98 American Head and Neck Society Nominating Committee, 1998 Chair, Web Site Committee, 1998 Education Committee, 1999-2002 Nominating Committee, 1999-2000 Ad hoc Informatics Committee, 1999-2000

University of Iowa Medical School Chairman Search Committee Member Chairman, Department of Otolaryngology (liaison member), 1995 Chairman, Division of Medical Oncology, 1998 Chairman, Division of Radiation Oncology, 1998

American Academy of Otolaryngology-Head and Neck Surgery Neurolaryngology Subcommittee, 1995-present University of Iowa Hospitals and Clinics Member, Cancer Center Advisory Subcommittee, January 2001-present Comprehensive Cancer Control Committee Member, Report to the State of Iowa Legislature, January 2002. Clinical Assignments Inpatient Care of three to four hospitalized patients per day for 45 weeks per year. Surgical procedures are performed three days per week, 45 weeks per year. Outpatient Tuesday and Thursday clinics average 75 patients per week, 45 weeks per year. Rev. 9/27/2007

Documents

COLLEGE OF MEDICINE CURRICULUM VITAE · COLLEGE OF MEDICINE CURRICULUM VITAE Henry T. Hoffman, M.D. Page 5 27th Annual, “Common Problems in Laryngology” and “Tumors of the Larynx