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CME QUESTIONS FOR JULY 2001 ISSUE OF THE JOURNAL OF UROLOGY 1. 20-YEAR OUTCOME FOR PATIENTS WITH T13N0 SURGICALLY STAGED PROSTATE CANCER TREATED WITH EXTERNAL BEAM RADIATION THERAPY (vol. 165, pp. 116 –118) After external beam radiation therapy for surgically staged node negative carcinoma of the prostate: a) 15-year cause specific survival is between 54% and 65% and remains stable with longer followup b) 15-year cause specific survival is 80% c) 15-year cause specific survival is between 54% and 65% but continues to decline with longer followup d) it is uncommon for patients who survive 10 years after radiation therapy to require additional hormonal therapy e) long-term followup is unnecessary since late recurrences are uncommon 2. SIGNIFICANT MEDICAL PATHOLOGY DISCOVERED DURING A MALE INFERTILITY EVALUATION (vol. 165, pp. 178 –180) The most uncommon unsuspected medical pathological condition identified during an evaluation for male infertility is: a) a malignancy b) a genetic abnormality c) a treatable endocrinopathy d) neurological disease e) vascular disease 3. PELVIC LYMPH NODE METASTASES FROM BLADDER CANCER: OUTCOME IN 83 PATIENTS AFTER RADICAL CYSTECTOMY AND PELVIC LYMPHADENECTOMY (vol. 165, pp. 19 –23) Five years survival following pelvic lymphadenectomy and radical cystectomy for carcinoma of the bladder: a) does not occur in any patient with positive nodes b) occurs despite the site of pelvic lymph node metastases c) only occurs with ipsilateral metastases d) is not influenced by the number of positive nodes e) is not influenced by lymph node capsule perforation by tumor 4. RELATIONSHIP BETWEEN SYSTEMATIC BIOPSIES AND HISTOLOGICAL FEATURES IN 222 RADICAL PROSTATECTOMY SPECIMENS: LACK OF PREDICTION OF TUMOR SIGNIFICANCE FOR MEN WITH NONPALPABLE PROSTATE CANCER (vol. 165, pp. 100 –106) The relationship of the histopathological features among 6 or more preoperative systematic prostate biopsies and the prostatectomy specimens is: a) excellent for secondary cancers b) best for transition zone cancers c) predictive of Gleason grades 3, 2 and 1 cancer d) predictive of cancer volume e) weak and nonpredictive of outcome 5. SCREENING AND MONITORING FOR BLADDER CANCER: REFINING THE USE OF NMP22 (vol. 165, pp. 75–78) Patients at risk for bladder cancer who eventually have bladder cancer evaluated with a single urine specimen by cytology and NMP22 assay: a) will have a positive cytology more than 90% of the time b) will have a positive NMP22 protein assay more than 85% of the time c) will not have a superficial tumor missed on NMP22 protein assay d) will all have microscopic or gross hematuria e) will not require cystoscopy 247

CME QUESTIONS FOR THE JULY 2001 ISSUE OF THE JOURNAL OF UROLOGY

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CME QUESTIONS FOR JULY 2001 ISSUE OFTHE JOURNAL OF UROLOGY

1. 20-YEAR OUTCOME FOR PATIENTS WITH T13N0 SURGICALLY STAGED PROSTATE CANCER TREATED WITHEXTERNAL BEAM RADIATION THERAPY (vol. 165, pp. 116–118)

After external beam radiation therapy for surgically staged node negative carcinoma of the prostate:

a) 15-year cause specific survival is between 54% and 65% and remains stable with longer followupb) 15-year cause specific survival is 80%c) 15-year cause specific survival is between 54% and 65% but continues to decline with longer followupd) it is uncommon for patients who survive 10 years after radiation therapy to require additional hormonal therapye) long-term followup is unnecessary since late recurrences are uncommon

2. SIGNIFICANT MEDICAL PATHOLOGY DISCOVERED DURING A MALE INFERTILITY EVALUATION (vol. 165,pp. 178–180)

The most uncommon unsuspected medical pathological condition identified during an evaluation for male infertility is:

a) a malignancyb) a genetic abnormalityc) a treatable endocrinopathyd) neurological diseasee) vascular disease

3. PELVIC LYMPH NODE METASTASES FROM BLADDER CANCER: OUTCOME IN 83 PATIENTS AFTERRADICAL CYSTECTOMY AND PELVIC LYMPHADENECTOMY (vol. 165, pp. 19–23)

Five years survival following pelvic lymphadenectomy and radical cystectomy for carcinoma of the bladder:

a) does not occur in any patient with positive nodesb) occurs despite the site of pelvic lymph node metastasesc) only occurs with ipsilateral metastasesd) is not influenced by the number of positive nodese) is not influenced by lymph node capsule perforation by tumor

4. RELATIONSHIP BETWEEN SYSTEMATIC BIOPSIES AND HISTOLOGICAL FEATURES IN 222 RADICALPROSTATECTOMY SPECIMENS: LACK OF PREDICTION OF TUMOR SIGNIFICANCE FOR MEN WITHNONPALPABLE PROSTATE CANCER (vol. 165, pp. 100–106)

The relationship of the histopathological features among 6 or more preoperative systematic prostate biopsies and theprostatectomy specimens is:

a) excellent for secondary cancersb) best for transition zone cancersc) predictive of Gleason grades 3, 2 and 1 cancerd) predictive of cancer volumee) weak and nonpredictive of outcome

5. SCREENING AND MONITORING FOR BLADDER CANCER: REFINING THE USE OF NMP22 (vol. 165, pp. 75–78)

Patients at risk for bladder cancer who eventually have bladder cancer evaluated with a single urine specimen bycytology and NMP22 assay:

a) will have a positive cytology more than 90% of the timeb) will have a positive NMP22 protein assay more than 85% of the timec) will not have a superficial tumor missed on NMP22 protein assayd) will all have microscopic or gross hematuriae) will not require cystoscopy

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