Clinical Drug Monitoring Reference Guide

Clinical Drug Monitoring Reference Guide

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P = Presumptive D = Definitive M = medMATCH®

Profile Name and Test Codes

Base Profile Profile 1 Profile 2 Profile 3 Profile 4 Profile 5 Profile 6 Profile 7 Profile 8

16260 16259 16457 92466 92450 92451 92458 92459 92467 92453 92461 16855 16854 16456 92468 92454 92462 90347 90348 92455 90318 92463 92456 92464 92457 92465 92489 92490

Drug Class P P,D,M P,D P P,D,M P,D,M P,D P,D P P,D,M P,D P P,D,M P,D P P,D,M P,D P P,D,M P,D,M P,D P,D P,D,M P,D P,D,M P,D P,D,M P,D

Alcohol Metabolites/ETG ALC ALC ALC ALC ALC ALC

Amphetamines AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP AMP

Amphetamines d/l Isomers ADL ADL ADL ADL

Barbiturates BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR BAR

Benzodiazepines BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN BEN

Buprenorphine BUP BUP

Cocaine Metabolite COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC COC

Heroin Metabolite HER HER HER HER HER HER

Marijuana Metabolite MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR MAR

MDMA/MDA MDM MDM

Methadone Metabolite MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH MTH

Opiates OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI OPI

Oxycodone OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY OXY

Phencyclidine PCP PCP PCP PCP PCP PCP PCP PCP PCP PCP

Clinical Drug MonitoringTest List with Test Codes

Test Profiles

Drug Class P P,D,M P,D D,M D

Alcohol Metabolites 90079 16910 92142 16217

Amphetamines 92222 70245 16885 70209 16913

Amphetamines with Reflex d/l Isomers 91590 91589 92484 92483

Antidepressants (urine) 94032

Antidepressants (serum) 94031

Antipsychotics (urine) 94528

Antipsychotics (serum) 94529

Barbiturates 92223 70246 16886 70230 16912

Benzodiazepines 92224 70247 16887 70231 16914

Buprenorphine 16207 70249 16901 18998 16213

Buprenorphine with Naloxone 93093 93094

Carisoprodol 18999 16902


Cocaine Metabolite 92225 70248 16888 90082 16916

Eszopiclone 91251

Fentanyl 36278 36279 36280 18996 16900

Gabapentin 70205 16904

Heroin Metabolite 92226 90081 16911 90333 90329

Marijuana Metabolite 92227 18989 16889 70233 16917

MDMA/MDA 92228 90078 16909 90334 90331

Meperidine 70206 16905

Methadone Metabolite 92229 18990 16890 70234 16918

Methamphetamine d/l Isomers 90319

Methylphenidate 90247 90246

Mitragynine 39241 39240


Naltrexone 93753

Opiates 92230 18991 16891 70237* 16298*

Oxycodone 92231 18992 16892 70238 16920

Phencyclidine 92232 18993 16893 90083 16921

Pregabalin 70208 16908

Propoxyphene 92233 18995 16894 70239 16922

Synthetic Cannabinoids 93027

Synthetic Stimulants 90322

Tapentadol 90244 90243

Tramadol 70207 16906

Tricyclic Antidepressants 70204 16903

Zolpidem 91258

*Includes oxycodone drug class

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Base Profile16260 (P), 16259 (P,D,M), 16457 (P,D)

BenzodiazepinesCocaine MetaboliteOpiatesOxycodone

Profile 192466 (P), 92450 (P,D,M), 92458 (P,D)

AmphetaminesBarbituratesBenzodiazepinesCocaine MetaboliteMarijuana MetaboliteMethadone MetaboliteOpiatesOxycodonePhencyclidine

Profile 1 with Amphetamines d/l Isomers92451 (P,D,M), 92459 (P,D)

Amphetamines with Reflex d/l IsomersBarbituratesBenzodiazepinesCocaine MetaboliteMarijuana MetaboliteMethadone MetaboliteOpiatesOxycodonePhencyclidine

Profile 292467 (P), 92453 (P,D,M), 92461 (P,D)

Methadone MetaboliteOpiatesOxycodone

P = Presumptive D = Definitive M = medMATCH®

Profile 316855 (P), 16854 (P,D,M), 16456 (P,D)

AmphetaminesBenzodiazepinesCocaine MetaboliteMarijuana MetaboliteOpiatesOxycodone

Profile 492468 (P), 92454 (P,D,M), 92462 (P,D)

AmphetaminesBarbituratesBenzodiazepinesCocaine MetaboliteMethadone MetaboliteOpiatesOxycodonePhencyclidine

Profile 590347 (P), 90348 (P,D,M), 90318 (P,D)

AmphetaminesBarbituratesBenzodiazepinesCocaine MetaboliteMarijuana MetaboliteMethadone MetaboliteOpiatesOxycodone

Profile 5 with Amphetamines d/l Isomers92455 (P,D,M), 92463 (P,D)

Amphetamines with Reflex d/l IsomersBarbituratesBenzodiazepinesCocaine MetaboliteMarijuana MetaboliteMethadone MetaboliteOpiatesOxycodone

Profile 692456 (P,D,M), 92464 (P,D)

Alcohol Metabolites/EtGAmphetaminesBarbituratesBenzodiazepinesCocaine MetaboliteHeroin MetaboliteMarijuana MetaboliteMethadone MetaboliteOpiatesOxycodonePhencyclidine

Profile 792457 (P,D,M), 92465 (P,D)

Alcohol Metabolites/EtGAmphetaminesBarbituratesBenzodiazepinesCocaine MetaboliteHeroin MetaboliteMarijuana MetaboliteMethadone MetaboliteOpiatesOxycodone

Profile 892489 (P,D,M), 92490 (P,D)

Alcohol Metabolites/EtGAmphetaminesBenzodiazepinesBuprenorphineCocaine MetaboliteHeroin MetaboliteMarijuana MetaboliteMDMA/MDAOpiatesOxycodone

For healthcare professionals seeking assistance with interpreting results, please contact a Quest Diagnostics Toxicology Specialist at 1.877.40.RX TOX (1.877.407.9869), M–F 8:00 AM to 10:00 PM ET.

Clinical Drug Monitoring Test Profiles

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Drug/Drug ClassPresumptive

Cutoff (ng/mL)Definitive

Cutoff (ng/mL)Reportable Drug or Metabolite

Additional Reportable Drug/Metabolitea Examples of Generic/Trade/Street Name Urine Detection Timea

Alcohol Metabolites 500500 Ethyl Glucuronide (EtG) Ethyl Sulfate (EtS)

Up to 80 Hours100 Ethyl Sulfate (EtS) Ethyl Glucuronide (EtG)

Amphetamines 500 250

Amphetamine Amphetamine — Adderall®, Dexedrine®, Dextrostat®, Vyvanse®

1–3 DaysMethamphetamine Amphetamine

Methamphetamine — Desoxyn®

Benzphetamine — Didrex®

Amphetamines with ReflexMethamphetamine d/l Isomers

500

250

Amphetamine Amphetamine — Adderall®, Dexedrine®, Dextrostat®, Vyvanse®

1–3 Days

Methamphetamine AmphetamineMethamphetamine — Desoxyn®

Benzphetamine metabolite — Didrex®

d-Methamphetamined-Methamphetamine — Desoxyn®

Benzphetamine d-metabolite — Didrex®

l-MethamphetamineSelegiline l-metabolite — Eldepryl®

l-Methamphetamine —nasal inhaler

Antidepressantsc 10 10

Amitriptyline Nortriptyline Amitriptyline — Elavil®, Endep®

1–3 Days

Amoxapine Amoxapine — Asendin®

Citalopram/Escitalopram Desmethylcitalopram Citalopram/Escitalopram — Celexa® (citalopram), Lexapro® (escitalopram)Desmethylcitalopram

Clomipramine DesmethylclomipramineClomipramine — Anafranil®

Desmethylclomipramine

Desipramine Imipramine Imipramine — Tofranil®

Desipramine — Norpramin®

Doxepin DesmethyldoxepinDoxepin — Adapin® , Sinequan®

Desmethyldoxepin

Duloxetine Duloxetine — Cymbalta®

Fluoxetine NorfluoxetineFluoxetine — Prozac®

Norfluoxetine

Fluvoxamine NorfluvoxamineFluvoxamine — Luvox®

Norfluvoxamine

Hydroxybupropion Hydroxybupropion — Aplenzin® (bupropion)

Imipramine Desipramine Imipramine — Tofranil®

Maprotiline Maprotiline — Ludiomil®

a Depends upon drug usage patterns, drug/drug metabolite elimination, and test cutoffb Naloxone is reported when orderedc Presumptive analysis uses mass spectrometry method of analysis

Note: Unless otherwise specified, the presumptive method of analysis is immunoassay.


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Antidepressantsc

10 10

Mirtazapine Mirtazapine — Remeron®

1–3 Days

Nortriptyline Amitriptyline Amitriptyline — Elavil®, Endep®

Nortriptyline — Aventyl®

Paroxetine Paroxetine — Paxil®, Seroxat®

Protriptyline Protriptyline — Vivactil®

Sertraline NorsertralineSertraline — Zoloft®

50 50 Norsertraline

10 10

Trazodone 1-(3-Chlorophenyl)piperazineTrazodone — Desyrel®

1-(3-Chlorophenyl)piperazine

Trimipramine Trimipramine — Surmontil®

Venlafaxine O-desmethylvenlafaxine Venlafaxine — Effexor® XR (venlafaxine), Khedezla (desvenlafaxine)O-desmethylvenlafaxine

Vilazodone Vilazodone — Viibryd®

Vortioxetine Vortioxetine — Trintellix®

Antipsychoticsc

22 Aripiprazole Dehydroxyaripiprazole

Aripiprazole — Abilify®

1–3 Days

10 Dehydroxyaripiprazole

5 5 Brexpiprazole Brexpiprazole — Rexulti®

5 5 Cariprazine Cariprazine — Vraylar®

10 10Chlorpromazine 7-OH-chlorpromazine

Chlorpromazine — Largactil, Thorazine®

7-OH-chlorpromazine

25 25Clozapine Norclozapine

Clozapine — Clozaril®

Norclozapine

5 5Fluphenazine 7-OH-fluphenazine

Fluphenazine — Prolixin®, Modecate7-OH-fluphenazine

1 1 Haloperidol Haloperidol — Haldol®

5 5Loxapine 8-hydroxyloxapine

Loxapine — Loxapac, Loxitane®

8-hydroxyloxapine

5 5 Lurasidone Lurasidone — Latuda®

10 10 Mesoridazine Mesoridazine — Serentil®

5 5 Molindone Molindone — Moban®

2.5 2.5Olanzapine Desmethylolanzapine

Olanzapine — Zyprexa®

Desmethylolanzapine




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Antipsychotics

10 10Quetiapine Norquetiapine

Quetiapine — Seroquel®

1–3 Days

Norquetiapine

5 5Risperidone OH-risperidone

Risperidone — Risperdal®

OH-risperidone

50 50 Thioridazine Thioridazine — Mellaril®, Melleril

5 5

Thiothixene Thiothixene — Navane®

Trifluoperazine Trifluoperazine — Stelazine®

Ziprasidone Ziprasidone — Geodon®, Zeldox

Barbiturates 300 100

AmobarbitalAmobarbital — Amytal®,

1–3 Days Short-Acting;

>3 Long-Acting

Secobarbital Amobarbital/Secobarbital Combination — Tuinal®

Butalbital Butalbital — Esgic®, Fioricet®, Fiorinal®, Sandoptal®

Pentobarbital Pentobarbital — Nembutal®

Phenobarbital Phenobarbital — Luminal®

SecobarbitalSecobarbital — Seconal®

Amobarbital Amobarbital/Secobarbital Combination — Tuinal®

Benzodiazepines 100

25 Alpha-hydroxyalprazolam Alprazolam — Xanax®

1–3 Days Short-Acting;

>3 Long-Acting

50Alpha-hydroxymidazolam Midazolam — Versed®

Alpha-hydroxytriazolam Triazolam — Halcion®

25 Aminoclonazepam Clonazepam — Klonopin®

50

Hydroxyethylflurazepam Flurazepam — Dalmane®

Lorazepam Lorazepam — Ativan®

NordiazepamOxazepam

Chlordiazepoxide — Librium®

Clorazepate — Tranxene®

Oxazepam, Temazepam Diazepam — Valium®

Oxazepam

Oxazepam — Librax®, Serax®

NordiazepamClorazepate — Tranxene®

Chlordiazepoxide — Librium®

Nordiazepam, Temazepam Diazepam — Valium®

TemazepamOxazepam Temazepam — Restoril®

Oxazepam, Nordiazepam Diazepam — Valium®




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Buprenorphine 5 2

BuprenorphineNorbuprenorphine, Naloxone

Buprenorphine/Naloxone Combinationb — Bunavil®, Suboxone®, Zubsolv®

1–3 DaysNorbuprenorphine

Buprenorphine — Buprenex®, Butrans®, Subutex®

Norbuprenorphine

Naloxoneb Buprenorphine, Norbuprenorphine

Buprenorphine/Naloxone Combinationb — Bunavil®, Suboxone®, Zubsolv®

Carisoprodol Metabolite

1000 MeprobamateCarisoprodol — Soma®, Equagesic®

Meprobamate — Milltown®, Equanil® 1–3 Days

Cocaine Metabolite 150 100 Benzoylecgonine Cocaine — Coke 1–3 Days

Eszopiclone 5 Eszopiclone Eszopiclone — Lunesta® 1–3 Days

Fentanyl 0.5 0.5Fentanyl Norfentanyl

Fentanyl — Abstral®, Actiq®, Duragesic®, Fentora®, Lonsys® 1–2 DaysNorfentanyl

Gabapentin 1000 Gabapentin Gabapentin — Fanatrex, Gabarone, Neurontin® 1–3 Days

Heroin Metabolite 10 10 6-Acetylmorphine Heroin — Heroin 1 Day

Marijuana Metabolite

20 5 Marijuana MetaboliteDronabinol — dronabinol, Marinol®

Marijuana — pot, weed1–3 Days Casual Use;

>3 Days Chronic Use

MDMA/MDA 500 200MDMA MDA Ecstasy

1-2 DaysMDA Sally

Meperidine 100/100Meperidine Normeperidine

Meperidine — Demerol® 1-3 DaysNormeperidine

Methadone Metabolite

100 100Methadone EDDP

Methadone — Dolophine® 1–3 DaysEDDP

Methylphenidate 100 Ritalinic Acid Methylphenidate — Ritalin®, Concerta® 1–3 Days

Mitragynine 50 2 Mitragynine Kratom 1–3 Days




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Naltrexone 5Naltrexone 6-beta-naltrexol

Naltrexone — ReVia®, Vivitrol® 1–3 Days6-beta-naltrexol

Opiates 100 50

CodeineMorphine

Codeine — Tylenol® #3, Tylenol® #4, Tylenol® w/Codeine, Acetaminophen w/Codeine, Phenaphen® w/Codeine, Phenergan® w/Codeine, Phenameth w/Codeine, Promethazine w/Codeine

1–3 Days

Poppy seed ingestion

Hydrocodone Codeine minor metabolite

Morphine

Morphine — Avinza®, Kadian®, MS Contin®, Roxanol®; Heroin

Codeine

Codeine — Tylenol® #3, Tylenol® #4, Tylenol® w/Codeine, Acetaminophen w/Codeine, Phenaphen® w/Codeine, Phenergan® w/Codeine, Phenameth w/Codeine, Promethazine w/Codeine

Poppy seed ingestion

Hydromorphone Morphine minor metabolite

Heroin Metabolite Heroin metabolite

Hydrocodone

Hydromorphone, Norhydrocodone

Hydrocodone — Hycodan®, Lorcet®, Lortab®, Norco®, Vicodin®

Codeine, Morphine Codeine minor metabolite

Hydromorphone

Hydromorphine — Dilaudid®

Hydrocodone, Norhydrocodone Hydrocodone — Hycodan®, Lorcet®, Lortab®, Norco®, Vicodin®

Morphine Morphine minor metabolite

Norhydrocodone Hydrocodone, Hydromorphone Hydrocodone — Hycodan®, Lorcet®, Lortab®, Norco®, Vicodin®

Oxycodone 100 50

Noroxycodone Oxycodone, OxymorphoneOxycodone — Endocet®, Magnacet®, OxyContin®, OxyFAST®, OxyIR®, Percocet®, Percodan®, Perolox®, Roxicet®, Roxicodone®, Tylox® 1–3 Days

Oxycodone Noroxycodone, Oxymorphone

OxymorphoneOxycodone, Noroxycodone

Oxymorphone — Opana®, Numorphan®

Phencyclidine 25 25 Phencyclidine Phencyclidine — PCP 1–3 Days

Pregabalin 1000 Pregabalin Pregabalin — Lyrica® 1–3 Days

Propoxyphene 300 200 Norpropoxyphene Propoxyphene — Darvon®, Davocet®, Dolene®, Progesic®, Trycet® 1–3 Days




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Synthetic Cannabinoidsc

2 2

AB-CHMINACA M2 AB-CHMINACA

1–3 Days

AB-FUBINACA M2 N-pentanoic acid

AB-FUBINACA

AB-PINACA AB-PINACA

ADBICA N-pentanoic acid ADBICA

ADB-PINACA N-pentanoic acid

ADB-PINACA

0.2 0.2 AKB48 N-pentanoic acid AKB48

2 2 BB-22 3-carboxyindole BB-22

0.2 0.2JWH-018 N-pentanoic acid JWH-018

JWH-073 N-butanoic acid JWH-073

2 2 PB-22 3-carboxyindole PB-22

0.2 0.2 UR-144 N-pentanoic acid UR-144

2 25-Fluoro-PB-22 3-carboxyindole

5-Fluoro-PB-22

Synthetic Stimulants

50

Butylone Butylone — Bk-MBDB

1–3 Days

MDPVMDPV — Bath salts, Ivory Wave, Vanilla Sky

MephedroneMephedrone — 4-MMC, Meow Meow, M-CAT, Bounce

Methylone Methylone — Bath salts

Tapentadol 50Tapentadol Nortapentadol

Tapentadol — Nucynta® 1–3 DaysNortapentadol

Tramadol 100Tramadol Desmethyltramadol

Tramadol — Rybix®, Ryzolt®, Ultram® 1–3 DaysDesmethyltramadol

Tricyclic Antidepressants

100Amitriptyline Nortriptyline Amitriptyline — Elavil®, Endep®

1–3 DaysNortriptyline Nortriptyline — Aventyl®, Pamelor®

Zolpidem 5Zolpidem Zolpidem Metabolite

Zolpidem — Ambien®, Edluar®, Intermezzo®, Zolpimist® 1–3 DaysZolpidem Metabolite


K2, Spice, Bliss, Blaze



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Clinical Drug Monitoring Reference Guide