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City of Hope Presents MULTIDISCIPLINARY APPROACHES TO CANCER SYMPOSIUM PASÉA HOTEL & SPA | HUNTINGTON BEACH, CA October 8 to 10, 2021 CityofHope.org

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City of Hope Presents

MULTIDISCIPLINARY APPROACHES TO CANCER SYMPOSIUM

PASÉA HOTEL & SPA | HUNTINGTON BEACH, CA

October 8 to 10, 2021

CityofHope.org

Table of Contents

Multidisciplinary Approaches to Cancer Symposium

WELCOME!

GENERAL INFORMATION

➢ Important Reminders

➢ Conference Details: Location, Times, etc.

CONFERENCE INFORMATION

➢ Credit Information

➢ Instructions for Obtaining CME Credit

▪ AMA PRA Category 1 Credit™

▪ PHYSICIANS ONLY: How to Obtain ABIM MOC Points

E-SYLLABUS

WIFI INFORMATION

MEET THE FACULTY RECEPTION

ACKNOWLEDGMENT OF COMMERCIAL EXHIBIT SUPPORT

CORE COMPETENCIES INFORMATION SHEET

DISCLOSURES

CONFERENCE SCHEDULE

CONFERENCE TASKS

➢ Link to Symposium Evaluation

➢ Link to ABIM MOC Activity Self-Assessment (Part II)

Multidisciplinary Approaches to Cancer Symposium

Welcome to the Multidisciplinary Approaches to Cancer Symposium, in

Huntington Beach, CA! On behalf of City of Hope and the Department of Continuing Medical Education, we would like to thank you for joining us for this educational activity. Interest and input from our participants encouraged us to continue to expand the focus of this symposium, incorporating requests and suggestions from attendees. The previous years of this symposium have been a great success and we are happy to have you join us this year. Our goal is to provide the desired information and skills which physicians and allied health care providers need in order to better serve their patient populations and research. Your thoughts are valuable and important, so please share them with us on the evaluation that will be emailed to you at the conclusion of the symposium. PHYSICIANS: An opportunity to claim ABIM MOC points for this activity will be made available via an ABIM MOC Activity Self-Assessment (Part II) at the conclusion of the conference. The links to the Evaluation and ABIM MOC Activity Self-Assessment (Part II) can also be accessed under the Conference Tasks page of this e-handout. Should you have any questions, please visit the conference staff at the registration desk. For post-conference CME information, please contact:

City of Hope Department of Continuing Medical Education

1500 E. Duarte Road, Bldg. #175 Duarte, CA 91010

[email protected] (626) 218-5622

General Information

Multidisciplinary Approaches to Cancer Symposium

Safety Protocols: REQUIRED: Masks are required in all conference space areas. Masks must always be worn correctly over your nose and mouth in all conference space areas. Click following link for General Safety Protocols for Live Conferences

Contactless Registrant Sign-in: You must confirm your attendance every day at the conference. During the conference you will be provided with a unique Code to record your attendance. You will need to text in the attendance code to the City of Hope CME text-in number (626-314-7448). Registrant sign-in, will also be facilitated via QR Code. To ensure you are ready for Contactless Registrant Sign-in:

1. Please be sure to have with you the cell phone (mobile) you registered in your in your CME Profile. If you have not done so yet, Confirm Your Registered Mobile Number Here! (you will only have to do this once)

• If mobile number is correct and you see the word “DONE!” simply close out the page. You are done!

• If you see “CONFIRM NUMBER”, your mobile number is not yet confirmed. To confirm it: 1. Click “DELETE NUMBER AND START OVER” 2. Enter your mobile number (do not include hyphens/dashes), to receive a confirmation code. 3. Enter Confirmation Code (this will be texted to you). 4. Click “CONFIRM NUMBER” and once you see “DONE!” close out the page. You are done!

2. Save the City of Hope CME text-in number as a contact in your cell phone: 626-314-7448 3. Please ensure your cell phone is fully charged, as charging stations will not be available in the conference

area.

.

General Information

Multidisciplinary Approaches to Cancer Symposium

MEETING MATERIALS Check-in at the registration desk to receive conference materials and your name badge.

CONFERENCE NAME BADGE Official conference name badge must be worn at all times to gain and maintain access to conference room and meals. If you misplace your badge, you will not be able to enter the conference area due to safety protocols in place. A replacement badge will not be provided.

CONFERENCE LOCATION EDUCATIONAL SESSIONS Paséa Hotel & Spa Sapphire 1 Ballroom 21080 Pacific Coast Highway Huntington Beach, CA 92648

REGISTRATION DESK- HOURS OF OPERATION

DATE AM SESSION TIME PM SESSION TIME LOCATION

Friday, October 8 7:20 a.m. – 11:40 a.m. 3:30 p.m. – 6:30 p.m. Sapphire Ballroom Foyer

Saturday, October 9 7:20 a.m. – 11:40 a.m. 3:30 p.m. – 6:30 p.m. Sapphire Ballroom Foyer

Sunday, October 10 7:20 a.m. – 11:40 a.m. ------ Sapphire Ballroom Foyer

CONFERENCE MEALS

DATE DESCRIPTION TIME LOCATION

Friday, October 8 Breakfast 7:20 a.m. – 8:00 a.m. Sapphire Ballroom 2/3

Friday, October 8 Lunch 11:40 a.m. (grab & go) ------

Friday, October 8 Refreshments 3:30 p.m. – 4:00 p.m. Sapphire Ballroom 2/3

Saturday, October 9 Breakfast 7:20 a.m. – 8:00 a.m. Sapphire Ballroom 2/3

Saturday, October 9 Lunch 11:40 a.m. (grab & go) ------

Saturday, October 9 Refreshments 3:30 p.m. – 4:00 p.m. Sapphire Ballroom 2/3

Saturday, October 9 Meet the Faculty Reception 6:30 p.m. – 7:30 p.m. Ocean Lawn

Sunday, October 10 Breakfast 7:20 a.m. – 8:00 a.m. Sapphire Ballroom 2/3

Sunday, October 10 Refreshments 9:50 a.m. – 10:10 a.m. Sapphire Ballroom 2/3

EXHIBIT HALL & HOURS

DATE TIME LOCATION

Friday, October 8 7:20 a.m. - 8:00 a.m.; 9:50 a.m. - 10:10 a.m.; 3:30 - 4:00 p.m. Sapphire Ballroom 2/3

Saturday, October 9 7:20 a.m. - 8:00 a.m.; 10:00 a.m. - 10:10 a.m.; 3:30 - 4:00 p.m. Sapphire Ballroom 2/3

Sunday, October 10 7:20 a.m. - 8:00 a.m.; 9:50 a.m. - 10:10 a.m. Sapphire Ballroom 2/3

Conference Information

Multidisciplinary Approaches to Cancer Symposium

Accreditation Statement City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement City of Hope designates this live activity for a maximum of 15.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the educational activity.

The following may apply AMA PRA Category 1 Credit™ for license renewal:

• Registered Nurses: Nurses may report up to 15.25 credit hours toward the continuing education requirements for license renewal by their state Board of Registered Nurses (BRN). CME may be noted on the license renewal application in lieu of a BRN provider number.

• Physician Assistants: The National Commission on Certification of Physician Assistants states that AMA PRA Category 1 Credit™ accredited courses are acceptable for continuing medical education requirements for recertification.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 15.25 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC)

program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Disclosure This activity has been planned and implemented in strict compliance with the accreditation requirements, standards and policies of the ACCME. City of Hope takes responsibility for the content, quality and scientific integrity of this CME activity. Faculty and Planners have provided written disclosure of all relevant commercial relationships which have been included in this handout. Any potential conflicts relative to the disclosure(s) have been resolved. City of Hope further encourages faculty/presenters to identify investigational products or off-label uses of products regulated by the U.S. Food and Drug Administration at first mention and where appropriate in the content. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

City of Hope may find it necessary to substitute faculty with comparable expertise on those rare occasions necessitated by illness, unforeseen scheduling conflicts or extraordinary occurrences beyond the control of City of Hope.

Conference Information

Multidisciplinary Approaches to Cancer Symposium

Instructions for Obtaining CME Credit (AMA PRA Category 1 Credit™): During the conference participants will be provided with a unique Attendance Code to record their attendance. Physicians and others who wish to receive AMA PRA Category 1 Credit™ for this activity must text in the unique attendance code for this conference, daily, in order to record their attendance. The unique attendance code will need to be texted to the City of Hope CME text-in number (626-314-7448). If you have not yet saved this number as contact on your cell phone, please do so now, to ensure you are ready to record your attendance. The text-in method will also be facilitated via a QR code that will be available upon check-in, at the conference registration desk. Credit Transcripts will be updated within a week to reflect your participation in this conference.

Retrieve your CME Transcripts by visiting the City of Hope CME website: https://cme.cityofhope.org/ Login using your registered Email and Password. Quick Tip! Have trouble remembering your password? Once you log in to your account, do not log out, so you do not have to log back in! Once logged in, click on the My Transcripts section at the top of the page, and click on “Completed Activities”. You can then print your Credit Transcript or the individual Certificate, if desired.

For assistance, contact the Department of Continuing Medical Education at 626-218-5622 or [email protected].

PHYSICIANS Seeking to Obtain ABIM MOC Points:

Physicians who wish to claim ABIM MOC points for this activity must comply with the instructions noted above to obtain AMA PRA Category 1 Credit™ as well as the following:

• Complete and successfully pass the ABIM MOC Activity Self-Assessment (Part II), which will be made available to all physicians at the conclusion of the conference.

o Minimum passing score of 70% will be required. o Participants will only have ONE opportunity to pass the Activity Self-Assessment (Part II).

Successful completion of the requirements noted above will award participants 15.25 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Credit Transcripts will be updated within 30 days of the conclusion of the conference, to reflect ABIM MOC points earned. IMPORTANT: Please ensure that your City of Hope CME portal profile accurately reflects your information, including Name, DOB, Specialty Board and Diplomate ID, to allow for successful reporting.

Confirm your profile is accurate here! For assistance, contact the Department of Continuing Medical Education at 626-218-5622 or [email protected].

E-Syllabus

Multidisciplinary Approaches to Cancer Symposium To ensure that you are receiving the most current slide sets presented, as well as keeping with City of Hope’s “green initiative” to reduce waste, an e-syllabus containing slide sets is available for this activity online only (printed presentation not available on-site). We recommend you access available presentations prior to the conference and bring your computer or mobile device fully charged. We gratefully acknowledge the presenters for their permission to offer this material as an e-syllabus.

Please Note: As an additional precautionary measure, furniture has been limited to only chairs within the general conference session.

E-Syllabus Download/Printing Instructions: (printed syllabus will not be provided on-site) If you would like to download or print a copy of available presentations simply:

1) Visit the following link: MAC 2021 | E-Syllabus 2) Find the desired presentation and click on the title of the presentation you would like to download

3) The presentation will open and appear in PDF format

4) To save the presentation, click "Save As"

5) To print the presentation, click "Print"

AJCC Cancer Staging Forms

• Access to the AJCC Cancer Staging Forms is also available via the e-syllabus.

PLEASE NOTE:

❖ Some presentations not provided prior to the conference will be accessible post-activity. ❖ All presentations will be available for 4 weeks following the conclusion of this educational activity. ❖ Presentations have been uploaded at the discretion of each faculty member.

WiFi Information

Multidisciplinary Approaches to Cancer Symposium

WiFi Network

“Pasea Wireless” (no password necessary)

Meet the Faculty Reception

Multidisciplinary Approaches to Cancer Symposium

You’re invited!

Meet the Faculty Reception

Saturday, October 9, 2021

OCEAN LAWN

6:30 – 7:30 p.m.

Registered attendees are invited to attend the Meet the Faculty Reception.

To comply with restrictions, no visitors/guests will be permitted.

Conference badge must be worn for admittance.

Commercial Support

CORE COMPETENCIES INFORMATION SHEET

PATIENT CARE Physicians must be able to provide patient care that is compassionate, appropriate, and effective for the treatment of health problems and the promotion of health. CME programs address these issues if they address topics related to:

• The ability to communicate effectively and demonstrate caring and respectful behaviors when interacting with patients and their families;

• gathering essential and accurate information about their patients

• making informed decisions about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment

• developing and carrying out patient management plans

• counseling and educating patients and their families

• using information technology to support patient care decisions and patient education

• performing competently all medical and invasive procedures considered essential for the area of practice

• providing health care services aimed at preventing health problems or maintaining health

• working with health care professionals, including those from other disciplines, to provide patient-focused care

MEDICAL KNOWLEDGE Physicians must demonstrate knowledge about established and evolving biomedical, clinical, and cognate (e.g. epidemiological and social-behavioral) sciences and the application of this knowledge to patient care. CME programs address these issues if the topics relate to:

• demonstration of an investigatory and analytic thinking approach to clinical situations

• knowledge and application of the basic and clinically supportive sciences which are appropriate to their discipline

PRACTICE-BASED LEARNING AND IMPROVEMENT Physicians must be able to investigate and evaluate their patient care practices, appraise and assimilate scientific evidence, and improve their patient care practices. CME programs address these issues if the topics relate to:

• analyzing practice experience and performing practice-based improvement activities using a systematic methodology

• locating, appraising, and assimilating evidence from scientific studies related to their patients’ health problems

• obtaining and using information about their own population of patients and the larger population from which their patients are drawn

• applying knowledge of study designs and statistical methods to the appraisal of clinical studies and other information on diagnostic and therapeutic effectiveness

• using information technology to manage information, access on-line medical information; and support their own education

• facilitating the learning of students and other health care professionals

INTERPERSONAL AND COMMUNICATION SKILLS Physicians must be able to demonstrate interpersonal and communication skills that result in effective information exchange and teaming with patients, their patients families, and professional associates. CME programs address these issues if the topics relate to:

• creating and sustaining a therapeutic and ethically sound relationship with patients

• using effective listening skills and eliciting and providing information using effective nonverbal, explanatory, questioning, and writing skills

• working effectively with others as a member or leader of a health care team or other professional group

PROFESSIONALISM Physicians must demonstrate a commitment to carrying out professional responsibilities, adherence to ethical principles, and sensitivity to a diverse patient population. CME programs address these issues if the topics relate to:

• demonstrating respect, compassion, and integrity; responsiveness to the needs of patients and society that supersedes self-interest; accountability to patients, society, and the profession; and a commitment to excellence and on-going professional development

• demonstrating a commitment to ethical principles pertaining to provision or withholding of clinical care, confidentiality of patient information, informed consent, and business practices

• demonstrating sensitivity and responsiveness to patients’ culture, age, gender, and disabilities

SYSTEMS-BASED PRACTICE Physicians must demonstrate an awareness of and responsiveness to the larger context and system of health care and the ability to effectively call on system resources to provide care that is of optimal value. CME programs address these issues if the topics relate to:

• understanding how their patient care and other professional practices affect other health care professionals, the health care organization, and the larger society and how these elements of the system affect their own practice

• knowing how types of medical practice and delivery systems differ from one another, including methods of controlling health care costs and allocating resources

• practicing cost-effective health care and resource allocation that does not compromise quality of care

• advocating for quality patient care and assisting patients in dealing with system complexities

• knowing how to partner with health care managers and health care providers to assess, coordinate, and improve health care and knowing how these activities can affect system performance

Department of Continuing Medical Education

Conflict of Interest Disclosure and Resolution & Core Competencies Multidisciplinary Approaches to Cancer Symposium

October 8-10, 2021

City of Hope takes responsibility for the content, quality, and scientific integrity of this CME activity.

As part of the commercial guidelines, we are required to disclose any real or apparent commercial conflict(s) of interest (COI) of all persons in control of educational content for this activity, specifically, but not limited to: faculty/presenters and/or planners. Any disclosed real or apparent commercial conflict(s) of interest (COI) have been resolved through a conflict resolution process prior to the beginning of this activity. City of Hope further requires that, if applicable, faculty/presenters disclose to the audience their intention to discuss the off-label and/or investigational (not yet approved for any purpose) use of pharmaceuticals or medical devices at the beginning of their presentation.

CORE COMPETENCIES The American Board of Medical Specialties (ABMS) and the Accreditation Council of Graduate Medical Education (ACGME) have embarked on a joint initiative to quantify and evaluate a set of 6 physician core competencies by which the individual physician will be measured for Residency Certification, Board Certification and more recently, Maintenance of Certification (MOC). Individual hospitals and other health care delivery organizations will now also be evaluated by the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) on their practice and demonstration of the 6 core competencies.

In brief, the actual term “core competencies” refers to those six abilities (competencies) that are central (core) to the practice of medicine, specifically: (1) Patient Care, (2) Medical Knowledge, (3) Practice-Based Learning and Improvement, (4) Interpersonal and Communication Skills, (5) Professionalism and (6) Systems-Based Practice. To assist our conferees in demonstrating their completion of CME in the six core competencies, the educational content of each presentation will be noted by numbers 1-6 in the table below. CME certificates for this activity will reflect those core competencies addressed by the educational content of the overall conference.

Conference Faculty Commercial Interest Conflict/ Resolution & Faculty Discussion of Off-Label Drugs

Core Competencies

Michelle Afkhami, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

Joseph Alvarnas, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2 & 6

Arya Amini, MD Grant/Research Support from Genentech; Consultant for Reflexion; On the Speakers Bureau for AstraZeneca, and Takeda Pharmaceuticals.

Attestation on file – No conflict noted 1, 2, 3, 4, 5 & 6

Chandana Banerjee MD, MPA I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

Linda Bosserman, MD, FASCO, FACP I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

Sorin Buga, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

Joseph Chao, MD Grant/Research Support from Merck; Consultant for Amgen, Astellas, AstraZeneca, Bristol-Myers Squibb, Daiichi-Sankyo, Foundation Medicine, Macrogenics, Merck, Ono Pharmaceuticals, Turning Point Therapeutics, Yiviva, Inc.; On the Speakers Bureau for Bristol-Myers Squibb, and Merck.

Attestation on file – No conflict noted 1, 2, 3, 4, 5 & 6

Conference Faculty Commercial Interest Conflict/ Resolution & Faculty Discussion of Off-Label Drugs

Core Competencies

Mike Chen, MD, PhD I do not have any relevant financial relationships with any commercial interests.

None 2 & 3

Christopher Chung, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

Tanya Dorff, MD Consultant for AbbVie, Advanced Accelerator Applications, Bayer, Exelixis, and Janssen.

Attestation on file – No conflict noted 1, 2 & 5

Lisa Feldman, MD, PhD I do not have any relevant financial relationships with any commercial interests.

None 1 & 2

Yuman Fong, MD Consultant for Boehringer Ingelheim, Eureka Therapeutics, and Imugene; Stock/Shareholder in Imugene; Other financial/material interests in Imugene, and Merck.

Attestation on file – No conflict noted Off-label/Investigational use of: Oncolytic Viruses CF33, & CF33-CD19.

1, 2 & 3

Scott Glaser, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3 & 6

Sherry Hite, MOT, OTR/L I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4 & 5

Misagh Karimi, MD I do not have any relevant financial relationships with any commercial interests.

None 3

Jonathan Kessler, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3 & 6

Jae Y. Kim, MD

Grant/Research Support from Eli Lilly.

Attestation on file – No conflict noted 1 & 2

Michael Lao, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3 & 6

Sayeh Lavasani, MD, MSc, FRCPC Consultant for Puma; On the Speakers Bureau for Puma, and Seagen.

Attestation on file – No conflict noted 1, 2, 3, 4, 5 & 6

Aram Lee, MD Consultant for Genentech; On the Speakers Bureau for Genentech.

Attestation on file – No conflict noted 1 & 2

Daneng Li, MD Grant/Research Support from Brooklyn Immunotherapeutics, and AstraZeneca; Consultant for Advanced Accelerator Applications, Eisai, Exelixis, Genentech, Ipsen, Merck, QED Therapeutics, and TerSera Therapeutics; On the Speakers Bureau for Coherus Biosciences, Eisai, Exelixis, Ipsen, Sun Pharma, and TerSera Therapeutics.

Attestation on file – No conflict noted Moderator

Yung Lyou, MD, PhD Consultant for Pfizer, and Seattle Genetics.

Attestation on file – No conflict noted 1 & 2

Erminia Massarelli, MD, PhD Consultant for Bristol-Myers Squibb, Janssen, Lilly, Merck, Sanofi; On the Speakers Bureau for AstraZeneca, Lilly, and Merck.

Attestation on file – No conflict noted 1, 2, 3, 4, 5 & 6

Conference Faculty Commercial Interest Conflict/ Resolution & Faculty Discussion of Off-Label Drugs

Core Competencies

Badri Modi, MD Consultant for Kadmon, Merck, Regeneron, and Sanofi-Genzyme; On the Speakers Bureau for Regeneron, and Sanofi-Genzyme.

Attestation on file – No conflict noted 1 & 2

Joanne Mortimer, MD, FACP, FASCO Consultant for AstraZeneca, GlaxoSmithKline, Incyte, Mesoblast, Novartis, Pfizer, and Puma Biotechnology.

Attestation on file – No conflict noted 1, 2, 3, 4 & 6

Danny Nguyen, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, & 3

Mustafa Raoof, MD, MS, FACS I do not have any relevant financial relationships with any commercial interests.

None 1, 2 & 3

Dan Raz, MD On the Speakers Bureau for AstraZeneca, and Roche.

Attestation on file – No conflict noted 1, 2, 3, 4, 5 & 6

Crystal Saavedra, BA I do not have any relevant financial relationships with any commercial interests.

None Planner

Ravi Salgia, MD, PhD Grant/Research Support from NIH/NCI; Consultant for AstraZeneca; On the Speakers Bureau for AstraZeneca, Merck, and Sanofi.

Attestation on file – No conflict noted 1, 2, & 3

Serafina Scorcia, BA I do not have any relevant financial relationships with any commercial interests.

None Planner

Tanya Siddiqi, MD Consultant for AstraZeneca, BeiGene, Bristol-Myers Squibb, Celgene, Juno Therapeutics, Kite Pharma, and Pharmacyclics; On the Speakers Bureau for AstraZeneca, Janssen, and Pharmacyclics.

Attestation on file – No conflict noted Off-label/Investigational use of: Lisaftoclax, Liso-cel, Ublituximab, Umbralisib, Pirtobrutinib, and Zanubrutinib.

1, 2, 3, 4, 5 & 6

Gagandeep Singh, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

Wade Smith, MD Consultant for Biotheranostics, and Novartis.

Attestation on file – No conflict noted 1 & 4

Joo Song, MD I do not have any relevant financial relationships with any commercial interests.

None Moderator

Daphne Stewart, MD, MS I do not have any relevant financial relationships with any commercial interests.

None 1, 2, 3, 4, 5 & 6

N. Simon Tchekmedyian, MD, FACP Stock/Shareholder for BioMarin Pharmaceuticals, Infinity Pharmaceuticals, Inc., Mereo BioPharma Group, Mersana Therapeutics, Inc., Myovant Sciences, and Novo Nordisk.

Attestation on file – No conflict noted 1, 2, 3 & 6

Victoria Meucci Villaflor, MD Grant/Research Support from Takeda; Consultant for AstraZeneca, Bristol-Myers Squibb, and Genentech; Stock/Shareholder in Johnson & Johnson.

Attestation on file – No conflict noted 1, 2, 3, 4, 5 & 6

Conference Faculty Commercial Interest Conflict/ Resolution & Faculty Discussion of Off-Label Drugs

Core Competencies

Terence Williams, MD, PhD Grant/Research Support from American Cancer Society, and National Institutes of Health; Consultant for Accuray, Candel Therapeutics, January Therapeutics, and Novocure.

Attestation on file – No conflict noted 1, 2 & 3

Christina Haeyoung Yeon, MD I do not have any relevant financial relationships with any commercial interests.

None Moderator

Ali Zhumkhawala, MD I do not have any relevant financial relationships with any commercial interests.

None 1, 2 & 6

Conference Schedule

Multidisciplinary Approaches to Cancer Symposium

FRIDAY, OCTOBER 8, 2021

AM SESSION:

7:20 - 8:00 AM REGISTRATION / BREAKFAST / EXHIBITS

8:00 - 8:20 AM Welcome & Announcements

8:20 - 8:50 AM Updates on Immunotherapy for Primary Brain Tumors Lisa Feldman, MD, PhD

8:50 - 9:20 AM Updates on the Systemic Therapy and Sequencing for Head and Neck Cancer Victoria Meucci Villaflor, MD

Tumor Board Session 9:20 - 9:50 AM Complex Cases: Optimal Management of Brain Metastases

Mike Chen, MD, PhD Arya Amini, MD N. Simon Tchekmedyian, MD, FACP

9:50 - 10:10 AM REFRESHMENT BREAK AND EXHIBITS

Plenary Session 10:10 - 10:40 AM Value-Based Oncology Care: Understanding Value, Cost, and Outcomes

Joseph Alvarnas, MD

10:40 - 11:10 AM Role of Cannabis for Cancer Patients: What Is the Data?

Sorin Buga, MD

11:10 - 11:40 AM End of Life: How to Meet the Needs of Patients When Treatment Is No Longer an Option

Chandana Banerjee, MD, MPA

11:40 AM ADJOURN AM SESSION

PM SESSION:

3:30 - 4:00 PM REGISTRATION/REFRESHMENTS/EXHIBITS OPEN

4:00 - 4:30 PM Non-Small Cell Lung Cancer (NSCLC) Optimal Sequence for Targeted Therapies

Ravi Salgia, MD, PhD

4:30 - 5:00 PM Non-Small Cell Lung Cancer (NSCLC) Optimal Sequence of Chemotherapy and Immunotherapy Erminia Massarelli, MD, PhD

5:00 - 5:30 PM What's New in Lung Cancer Screening?

Dan Raz, MD

5:30 - 6:00 PM Moving the Needle Forward in Lung Cancer with Radiation: Combinations with Targeted Therapies Terence Williams, MD, PhD

6:00 - 6:30 PM Management of Oligometastatic Disease Jonathan Kessler, MD

Arya Amini, MD Jae Y. Kim, MD Danny Nguyen, MD

6:30 PM ADJOURN PM SESSION

Conference Schedule

Multidisciplinary Approaches to Cancer Symposium

SATURDAY, OCTOBER 9, 2021

AM SESSION:

7:20 - 8:00 AM REGISTRATION / BREAKFAST / EXHIBITS

8:00 - 8:20 AM Welcome & Announcements 8:20 - 8:50 AM Management of Immunotherapy Related Toxicities Yung Lyou, MD, PhD

8:50 - 9:20 AM Optimal Sequencing of Treatment for Advanced Gastric and Esophageal Cancer Joseph Chao, MD

Tumor Board Session 9:20 - 10:00 AM Multidisciplinary Approach to Optimal Management of Colorectal Cancer Liver Metastases Aram Lee, MD

Mustafa Raoof, MD, MS, FACS Arya Amini, MD Misagh Karimi, MD

10:00 - 10:10 AM REFRESHMENT BREAK AND EXHIBITS

Plenary Session 10:10 - 10: 40 AM Role of Oncolytic Virus in Oncology From Laboratories to Clinics Yuman Fong, MD

10:40 - 11:10 AM Genomic Profiling of Myeloid and Lymphoblastic Leukemia: When & What to Order? Michelle Afkhami, MD

11:10 - 11:40 AM Management of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Tanya Siddiqi, MD

11:40 AM ADJOURN AM SESSION

PM SESSION:

3:30 - 4:00 PM REGISTRATION/REFRESHMENTS/EXHIBITS

4:00 - 4:30 PM Role of Surgical Resection in Advanced Neuroendocrine Tumors

Gagandeep Singh, MD

4:30 - 5:00 PM Advanced Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma

Badri Modi, MD

5:00 - 5:30 PM Male Sexual Health in Cancer Patients

Michael Lao, MD

5:30 - 6:00 PM Optimizing Management of Advanced Prostate Cancer: Multidisciplinary Approaches Tanya Dorff, MD

6:00 - 6:30 PM Early Stage Prostate Cancer: Management Decisions - Efficacy vs Quality of Life Considerations

Scott Glaser, MD Ali Zhumkhawala, MD

6:30 PM ADJOURN PM SESSION

6:30 - 7:30 PM MEET THE FACULTY RECEPTION

Conference Schedule

Multidisciplinary Approaches to Cancer Symposium

SUNDAY, OCTOBER 10, 2021

7:20 - 8:00 AM REGISTRATION / BREAKFAST / EXHIBITS

8:00 - 8:20 AM Welcome & Announcements 8:20 - 8:50 AM Optimal Length of Hormone Therapy for Early-Stage Hormone Receptor Positive Breast Cancer Wade Smith, MD 8:50 - 9:20 AM HER2 Positive Breast Cancer: Past, Present and Future Sayeh Lavasani, MD, MSc, FRCPC 9:20 - 9:50 AM Survivorship: Key Considerations When Building a Breast Cancer Program

Joanne Mortimer, MD, FACP, FASCO

9:50 - 10:10 AM REFRESHMENT BREAK AND EXHIBITS

10:10 - 10: 40 AM Highlights of Gynecologic Malignancies

Daphne Stewart, MD, MS

10:40 - 11:10 AM Pelvic Floor Disorders in Female Cancer Survivors

Christopher Chung, MD

11:10 - 11:40 AM Understanding and Addressing Sexuality Issues in Cancer Patients

Linda Bosserman, MD, FASCO, FACP Sherry Hite, MOT, OTR/L

11:40 AM ADJOURN SYMPOSIUM

City of Hope may find it necessary to substitute faculty with comparable expertise on those rare occasions necessitated by illness, unforeseen scheduling conflicts or extraordinary occurrences beyond the control of City of Hope.

Conference Tasks

Multidisciplinary Approaches to Cancer Symposium

CONFERENCE TASKS: Symposium Evaluation opens 10/10/2021 at 11:45am: https://cme.cityofhope.org//node/5194/course-object/14999 Conference Feedback Survey opens 10/10/2021 at 11:45am: https://cme.cityofhope.org//node/5194/course-object/12783

Physicians who wish to claim ABIM MOC points for this activity must:

• Text in the unique attendance code provided at the conference to be marked attended.

• Complete and successfully pass the ABIM MOC Activity Self-Assessment (Part II) o Minimum passing score of 70% will be required. o Participants will only have ONE opportunity to pass the Activity Self-Assessment.

ABIM MOC Activity Self-Assessment (Part II) opens 10/10/2021 at 11:45am: https://cme.cityofhope.org//node/5194/course-object/12782 IMPORTANT: Last day to complete Conference Tasks is: 10/17/2021

For assistance, contact the Department of Continuing Medical Education at 626-218-5622 or [email protected].