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Harvard Medical School presents… CHILD NEUROLOGY 2013 Monday, September 30 – Friday, October 4, 2013 Royal Sonesta Hotel, 40 Edwin H. Land Boulevard, Cambridge, MA Harvard Medical School • Department of Continuing Education Course Directors Katherine B. Sims, MD, Professor of Neurology, Harvard Medical School Kevin Staley, MD, Chief, Pediatric Neurology, Professor, Harvard Medical School Course Administrator Virginia Tosney-Trask Course Description This activity is designed to provide the pediatrician, adult and child neurologist, clinical psychologist, pediatric psychiatrist or family practitioner with an overview and update of important areas of child neurology in which recent scientific and clinical advances are changing the way we understand and treat disorders of the child’s brain development and function. Topics addressed include neurodevelopment, epilepsy and associated disorders, neurogenetics, stroke, brain tumors, and neurobehavioral and metabolic disorders. Didactic lectures, case-based and interactive formats will be used to cover these topics. Interactive workshops will include anticonvulsant use, sleep management, ADHD management, neurobehavioral management, pain management, headache management, concussion management and stroke management. An activity highlight is the presentation of patient cases for discussion and examination on Thursday evening in the Ether Dome at Massachusetts General Hospital. Learning Objectives Upon completion of this course, participants will be able to: Recognize the clinical features and discuss current categorization of the wide scope of neurodevelopmental and pediatric neurologic disorders highlighted in this course Develop a strategy for the diagnostic work-up of the common and some of the rarer pediatric neurology problems seen in the clinic Understand diagnostic tools available to the pediatric neurologist for patient evaluation and follow-up, including the currently available molecular genetic screening resources Discuss the management tools available to the pediatric neurologist for ongoing care including stabilization measures and direct treatment options Summarize current dilemmas and research advances for all topics and disor - ders presented in this course Target Audience Physicians, Psychologists, Mental Health Professionals, Residents Accreditation The Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Harvard Medical School designates this live activity for a maximum of 41.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. ACGME Competencies This course is designed to meet one or more of the following Accreditation Council of Graduate Medical Education competencies: • Patient care • Medical knowledge • Practice-based learning and improvement Registration Information Physicians: $1,450 (USD) Reduced Fee for Residents, Fellows in Training, and Allied Health Professionals: $975 (USD) Registration by credit card (VISA or MasterCard) can be made at: www.cme.hms. harvard.edu/courses/childneurology2013. Registration by check (draft on a United States bank), please make payable to Harvard Medical School and mail with registration form to Harvard Medical School–Department of Continuing Education, PO Box 417476, Boston, MA 02241-7476. Mail-in registration is permitted. Please download, then mail the registration panel found on the online PDF. Telephone or fax registration is not accepted. Registration with cash payment is not permitted. Upon receipt of your paid registration an email confirmation from the HMS-DCE office will be sent to you. Be sure to include an email address that you check frequently. Your email address is used for critical information, including registration confirmation, evaluation, and certificate. Inquiries By phone 617-384-8600, Monday–Friday, 10 am to 4 pm (EST) or by email at: [email protected]. Online Information To register or view activity information online, visit: www.cme.hms.harvard.edu/ courses/childneurology2013. Disclosure Policy Harvard Medical School (HMS) adheres to all ACCME Essential Areas, Standards, and Policies. It is HMS’s policy that those who have influenced the content of a CME activity (e.g., planners, faculty, authors, reviewers, and others) disclose all relevant financial relationships with commercial entities so that HMS may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations. Refund Policy A handling fee of $60 is deducted for cancellation. Refund requests must be received by postal mail, email, or fax one week prior to this activity. No refunds will be made thereafter. Course Location All sessions for this activity will be held at the Royal Sonesta Hotel, 40 Edwin H. Land Boulevard, Cambridge, MA (Telephone: 617-806-4200). Accommodations/Travel A limited number of rooms have been reserved at Royal Sonesta Hotel (Telephone: 617-806-4200) until September 9, 2013. Please specify that you are enrolled in this course to receive a reduced room rate of $269 per night Single/Double. Hotel arrangements can also be made online at: http://www.Sonesta.com/Boston, Group Code: HMSI13B. Please do not purchase non-refundable airline ticket(s) until you have received an email from our office confirming your paid registration. For airline reservations contact the HMS Travel Desk toll free 1-877-4-HARVMD (1-877-442-7863) Monday–Friday, 9 am–8 pm (EST). From outside the U.S., Canada, and Virgin Islands, please call 617-559-3764. HMS FACUlTy: MATT BIANCHI, MD, PHD FERDINAND BUONANNO, MD BRADLEY BUCHBINDER, MD PAUL CARUSO, MD VERNE CAVINESS, MD, DPHIL TANUJA CHITNIS, MD CATHERINE CHU, MD TINA DUHAIME, MD DAVID EBB, MD FLORIAN EICHLER, MD KITT FARR, MD VERA FRIDMAN, MD ERIC GRABOWSKI, MD ELLEN GRANT, MD PADMA GULUR, MD MARTHA HERBERT, MD, PHD ROBIN JONES, MD AMEL KARAA, MD KALPATHY KRISHNAMOORTHY, MD FLO LAI, MD FAWN LEIGH, MD CHRISTOPHER MCDOUGLE, MD WILLIAM MEEHAN, MD CAITLIN MERRILL, NP GANESH MOCHIDA, MD AMY MORGAN, PHD SARAH MURPHY, MD PATRICIA MUSOLINO, MD, PHD ANN NEUMEYER, MD JEFFERSON PRINCE, MD DRUCILLA ROBERTS, MD PETER ROSENBERGER, MD INDERNEEL SAHAI, MD KENNETH SASSOWER, MD JEREMIAH SCHARF, MD, PHD JEREMY SCHMAHMANN, MD KATHERINE SIMS, MD KEVIN STALEY, MD JOSEPH THAKURIA, MD RONALD THIBERT, DO ELIZABETH THIELE, MD, PHD M. ZELIME WARD, MD JEFF WAUGH, MD, PHD Online registrants add the first three characters of the source code here Source Code: W E B CHILD NEUROLOGY 2013 Monday, September 30 – Friday, October 4, 2013 Class #331195 Physicians: $1,450 (USD) Reduced Fee for Residents, Fellows in Training, and Allied Health Professionals: $975 (USD) Print Name Clearly – All Fields Required Full Name First Middle Initial Last Mailing Address Street City State Zip Code Daytime Phone ( ) Fax Number ( ) PLEASE NOTE: Your email address is used for critical information about the course including: registration confirmation, course evaluation, and certificate. Please be sure to include an email address you check daily or frequently. Email Address Please check if you wish to be excluded from receiving email notices of future HMS-DCE programs. Profession Degree Primary Specialty (Physicians Only) Board Certified: Yes No Professional School Attended (Physicians Only) Harvard Medical School U.S. Medical School International Year of Graduation

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Page 1: Child Neurology 2013

Harvard Medical School presents…

CHILD NEUROLOGY 2013Monday, September 30 – Friday, October 4, 2013

Royal Sonesta Hotel, 40 Edwin H. Land Boulevard, Cambridge, MA

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Course Directors Katherine B. Sims, MD, Professor of Neurology, Harvard

Medical SchoolKevin Staley, MD, Chief, Pediatric Neurology, Professor,

Harvard Medical School

Course AdministratorVirginia Tosney-Trask

Course Description This activity is designed to provide the pediatrician, adult and child neurologist, clinical psychologist, pediatric psychiatrist or family practitioner with an overview and update of important areas of child neurology in which recent scientific and clinical advances are changing the way we understand and treat disorders of the child’s brain development and function. Topics addressed include neurodevelopment, epilepsy and associated disorders, neurogenetics, stroke, brain tumors, and neurobehavioral and metabolic disorders. Didactic lectures, case-based and interactive formats will be used to cover these topics. Interactive workshops will include anticonvulsant use, sleep management, ADHD management, neurobehavioral management, pain management, headache management, concussion management and stroke management. An activity highlight is the presentation of patient cases for discussion and examination on Thursday evening in the Ether Dome at Massachusetts General Hospital.

Learning ObjectivesUpon completion of this course, participants will be able to:• Recognizetheclinicalfeaturesanddiscusscurrentcategorizationofthewide

scope of neurodevelopmental and pediatric neurologic disorders highlighted in this course

• Developastrategyforthediagnosticwork-upofthecommonandsomeoftherarer pediatric neurology problems seen in the clinic

• Understanddiagnostictoolsavailabletothepediatricneurologistforpatientevaluation and follow-up, including the currently available molecular genetic screening resources

• Discussthemanagementtoolsavailabletothepediatricneurologistforongoingcareincludingstabilizationmeasuresanddirecttreatmentoptions

• Summarizecurrentdilemmasandresearchadvancesforalltopicsanddisor-ders presented in this course

Target AudiencePhysicians,Psychologists,MentalHealthProfessionals,Residents

AccreditationThe Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Harvard Medical School designates this live activity for a maximum of 41.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ACGME CompetenciesThis course is designed to meet one or more of the following Accreditation Council of Graduate Medical Education competencies: •Patientcare •Medicalknowledge •Practice-based learning and improvement

Registration InformationPhysicians: $1,450 (USD)ReducedFeeforResidents,FellowsinTraining, and Allied Health Professionals: $975 (USD)

Registrationbycreditcard(VISAorMasterCard)canbemadeat:www.cme.hms.harvard.edu/courses/childneurology2013.Registrationbycheck(draftona United States bank), please make payable to Harvard Medical School and mail with registration form to Harvard Medical School–Department of Continuing Education, PO Box 417476, Boston, MA 02241-7476. Mail-in registration is permitted. Please download, then mail the registration panel found on the online PDF.Telephoneorfaxregistrationisnotaccepted.Registrationwithcashpaymentis not permitted. Upon receipt of your paid registration an email confirmation from the HMS-DCE office will be sent to you. Be sure to include an email address that you check frequently. Your email address is used for critical information, including registration confirmation, evaluation, and certificate.

InquiriesByphone617-384-8600,Monday–Friday,10am to 4 pm (EST) or by email at: [email protected].

Online InformationTo register or view activity information online, visit: www.cme.hms.harvard.edu/courses/childneurology2013.

Disclosure PolicyHarvard Medical School (HMS) adheres to all ACCME Essential Areas, Standards, and Policies. It is HMS’s policy that those who have influenced the content of a CME activity (e.g., planners, faculty, authors, reviewers, and others) disclose all relevant financial relationships with commercial entities so that HMS may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations.

Refund PolicyAhandlingfeeof$60isdeductedforcancellation.Refundrequestsmustbereceivedby postal mail, email, or fax one week prior to this activity. No refunds will be made thereafter.

Course LocationAll sessions for this activity will be held at the RoyalSonestaHotel,40EdwinH.Land Boulevard, Cambridge, MA (Telephone: 617-806-4200).

Accommodations/TravelAlimitednumberofroomshavebeenreservedatRoyalSonestaHotel(Telephone:617-806-4200) until September 9, 2013. Please specify that you are enrolled in this course to receive a reduced room rate of $269 per night Single/Double. Hotel arrangements can also be made online at: http://www.Sonesta.com/Boston, Group Code: HMSI13B. Please do not purchase non-refundable airline ticket(s) until you have received an email from our office confirming your paid registration. ForairlinereservationscontacttheHMSTravelDesktollfree1-877-4-HARVMD (1-877-442-7863)Monday–Friday,9am–8 pm(EST).FromoutsidetheU.S.,Canada,andVirginIslands,pleasecall617-559-3764.

HMSFACUlTy: Matt Bianchi, MD, PhD • FerDinanD Buonanno, MD • BraDley BuchBinDer, MD • Paul caruso, MD • Verne caViness, MD, DPhil • tanuja chitnis, MD • catherine chu, MD • tina DuhaiMe, MD • DaViD eBB, MD • Florian eichler, MD • Kitt Farr, MD • Vera FriDMan, MD • eric GraBowsKi, MD ellen Grant, MD • PaDMa Gulur, MD • Martha herBert, MD, PhD • roBin jones, MD • aMel Karaa, MD • KalPathy KrishnaMoorthy, MD • Flo lai, MD • Fawn leiGh, MD • christoPher McDouGle, MD • williaM Meehan, MD • caitlin Merrill, nP • Ganesh MochiDa, MD • aMy MorGan, PhD • sarah MurPhy, MD • Patricia Musolino, MD, PhD • ann neuMeyer, MD • jeFFerson Prince, MD • Drucilla roBerts, MD • Peter rosenBerGer, MD • inDerneel sahai, MD • Kenneth sassower, MD • jereMiah scharF, MD, PhD • jereMy schMahMann, MD • Katherine siMs, MD • KeVin staley, MD • josePh thaKuria, MD • ronalD thiBert, Do • elizaBeth thiele, MD, PhD • M. zeliMe warD, MD • jeFF wauGh, MD, PhD

Online registrants add the first three characters of the source code here ➞ Source Code: W E B

CHILD NEUROLOGY 2013 Monday, September 30 – Friday, October 4, 2013 Class #331195

Physicians: ❏ $1,450 (USD) Reduced Fee for Residents, Fellows in Training, and Allied Health Professionals: ❏ $975 (USD)

Print Name Clearly – All Fields Required

Full Name First Middle Initial Last

Mailing Address Street City State Zip Code

Daytime Phone ( ) Fax Number ( )PLEASE NOTE: Your email address is used for critical information about the course including: registration confirmation, course evaluation, and certificate. Please be sure to include an email address you check daily or frequently.

Email Address ❏ Please check if you wish to be excluded from receiving email notices of future HMS-DCE programs.

Profession Degree

Primary Specialty (Physicians Only) Board Certified: ❏ Yes ❏ No

Professional School Attended (Physicians Only) ❏ Harvard Medical School ❏ U.S. Medical School ❏ International Year of Graduation

Page 2: Child Neurology 2013

CHILD NEUROLOGY 2013 SCHEDULE

MONDAY, SEPTEMbER 30, 2013

7:00–8:00 am Registration and Continental Breakfast

8:00–8:15 Welcome, Introduction, and CME InstructionsKevin Staley, MD, Joseph P. & Rose F. Kennedy Professor of Child Neurology & Mental Retardation, HMS

8:15–9:00 KEynOTE ADDRESS: Promise, Power, Pitfalls of Whole Exome SequencingKatherine Sims, MD, Professor of Neurology, HMS

9:00–9:45 Multiple Sclerosis & Demyelinating DisordersTanuja Chitnis, MD, Associate Professor of Neurology, HMS

9:45–10:15 Metabolic Mimics of Cerebral PalsyKalpathy Krishnamoorthy, MD, Associate Professor of Pediatrics & Neurology, HMSFlorian Eichler, MD, Assistant Professor in Neurology, HMS

10:15–10:30 Coffee Break

10:30–12:00 neonatal neurology: Fetal, Placental ImagingPaul Caruso, MD, Instructor in Radiology, HMS Kalpathy Krishnamoorthy, MD, Associate Professor of Pediatrics & Neurology, HMSDrucilla Roberts, MD, Associate Professor of Pathology, HMS

12:00–1:30 pm BuffetlunchwithCourseFaculty

1:30–2:30 Benign Childhood Focal Epilepsy SyndromesCatherine Chu, MD, Assistant Professor of Neurology, HMS

2:30–3:15 Angelman Syndrome and 15q DeletionsRonald Thibert, DO, Instructor in Neurology

3:15–3:30 Coffee Break

3:30–4:30 Epilepsy Surgery & ImagingTina Duhaime, MD, Nicholas T. Zervas, Professor of Neurosurgery, HMSBradley Buchbinder, MD, Assistant Professor of Radiology

4:30–6:00 WORKSHOP: Anticonvulsant UseElizabeth Thiele, MD, PhD, Professor of Neurology, HMS

6:00 Adjourn

TUESDAY, OCTObER 1, 2013

7:00–7:55 am Continental Breakfast

7:55–8:00 Daily UpdateKatherine Sims, MD,Professor of Neurology, HMS Florian Eichler, MD, Assistant Professor in Neurology, HMS

8:00–9:00 Sleep Disorders – ClassificationKenneth Sassower, MD, Instructor in Neurology, HMS

WORKSHOP: Sleep ManagementMatt Bianchi, MD, PhD, Assistant Professor in Neurology, HMS

9:00–9:45 Ataxia and Cerebellar DysfunctionJeremy Schmahmann, MD, Professor of Neurology, HMS

9:45–10:00 Coffee Break

10:00–10:45 Learning DisordersFlo Lai, MD, Assistant Professor of Neurology, HMS

10:45–11:45 ADHD – Characterization, Classification

WORKSHOP: ADHD ManagementJefferson Prince, MD, Instructor in Psychiatry, HMS

11:45–1:15 pm Lunch (on your own)

1:15–2:00 Diagnosis and Pharmacological Treatment of Autism Spectrum DisorderChristopher McDougle, MD, Nancy Lurie Marks Professor of Psychiatry, HMS

2:00–3:00 Autism: Medical Issues, ManagementAnn Neumeyer, MD, Assistant Professor of Neurology, HMS

3:00–3:15 Coffee Break

3:15–4:00 Autism: Research UpdateMartha Herbert, MD, PhD, Assistant Professor of Neurology, HMS

4:00–4:45 neuropsychological Assessment of neurodevelopmental Disorders Amy Morgan, PhD, Instructor in Psychology, HMS

4:45–6:00 neurobehavioral Classification

WORKSHOP: neurobehavioral ManagementM. Zelime Ward, MD, Assistant in Neurology, HMS

6:00 Adjourn

WEDNESDAY, OCTObER 2, 2013

7:00–7:55 am Continental Breakfast

7:55–8:00 Daily UpdateKatherine Sims, MD, Professor of Neurology, HMS Florian Eichler, MD, Assistant Professor in Neurology, HMS

8:00–8:45 Common Genetic SyndromesJoseph Thakuria, MD, Instructor in Pediatrics, HMS

8:45–9:30 neurometabolic DisordersInderneel Sahai, MD, Lecturer in Pediatrics, MGH

9:30–10:15 Lysosomal Disorders/nCL DisordersAmel Karaa, MD, Clinical Fellow in Neurology, BWHKatherine Sims, MD, Professor of Neurology, HMS

10:15–10:30 Coffee Break

10:30–11:15 Tuberous SclerosisElizabeth Thiele, MD, PhD, Professor of Neurology, HMS

11:15–12:00 neurofibromatosisFawn Leigh, MD, Instructor in Neurology, HMS

12:00–1:30 pm Lunch (on your own)

WEDNESDAY, OCTObER 2, 2013 (COnTinUED)

1:30–2:30 neuromuscular DisordersFawn Leigh, MD, Instructor in Neurology, HMS

2:30–3:30 Autonomic Dysfunction in ChildrenVerne Caviness, MD, DPhil, Giovanni Armenise Distinguished Professor of Neurology, HMSKitt Farr, MD, Newton Wellesley Hospital, Cardiology

3:30–3:45 Coffee Break

3:45–4:30 Inherited neuropathiesVera Fridman, MD, Instructor in Neurology, HMS

4:30–5:15 WORKSHOP: Pain ManagementPadma Gulur, MD, Assistant Professor of Anesthesia, HMS

5:15–6:30 Palliative Care in Child neurologyCaitlin Merrill, NP, Massachusetts General Hospital for Children, Pediatric Palliative Care Program

THURSDAY, OCTObER 3, 2013

7:00–7:55 am Continental Breakfast

7:55–8:00 Daily UpdateKatherine Sims, MD, Professor of Neurology, HMS Florian Eichler, MD, Assistant Professor in Neurology, HMS

8:00–9:00 new Imaging TechnologiesEllen Grant, MD, Associate Professor of Radiology, HMS

9:00–10:00 Leukodystrophies and Hypomyelinating DisordersFlorian Eichler, MD, Assistant Professor in Neurology, HMS

10:00–10:15 Coffee Break

10:15–11:15 Headache Classification

WORKSHOP: Headache ManagementKevin Staley, MD, Joseph P. & Rose F. Kennedy Professor of Child Neurology & Mental Retardation, HMS

11:15–12:15 pm Mitochondrial DisordersKatherine Sims, MD, Professor of Neurology, HMS

12:15–1:30 Lunch Provided

1:30–2:30 Pediatric neurorehabilitationKaren Kerman, MD, Assistant Professor of Neurology & Pediatrics, Alpert Medical School, Brown University

2:30–3:15 Cerebral DysgenesisGanesh Mochida, MD, Assistant Professor of Neurology, HMS

3:15–3:30 Coffee Break

3:30–4:15 Tourette Syndrome & Related Tic Disorders: More Than Meets the EyeJeremiah Scharf, MD, PhD, Assistant Professor of Neurology, HMS

4:15–5:00 Dystonia and Other Movement DisordersJeff Waugh, MD, PhD, Clinical Fellow in Neurology, HMS

5:00–6:30 Dinner (on your own)

6:30–9:00 Live Patient Case Presentations @ the MGH Ether Dome Peter Rosenberger, MD, and faculty

FRIDAY, OCTObER 4, 2013

7:00–7:55 am Continental Breakfast

7:55–8:00 Daily UpdateKatherine Sims, MD, Professor of Neurology, HMS Florian Eichler, MD, Assistant Professor in Neurology, HMS

8:00–8:45 neuroOncology: Clinical SpectrumRobin Jones, MD, Assistant Professor of Neurology, HMS

8:45–9:30 neuroOncology ImagingPaul Caruso, MD, Instructor in Radiology, HMS

9:30–10:15 neuroOncology ManagementDavid Ebb, MD, Assistant Professor of Pediatrics, HMS

10:15–10:30 Coffee Break

10:30–11:30 neurointensive Care: nICU & PICUPatricia Musolino, MD, PhD, Clinical Fellow in Neurology, HMSSarah Murphy, MD, Instructor in Pediatrics, HMS

11:30–1:00 pm Lunch (on your own)

1:00–2:15 Concussion: neurosurgical Approaches to Head TraumaTina Duhaime, MD, Nicholas T. Zervas Professor of Neurosurgery, HMS

WORKSHOP: Concussion ManagementWilliam Meehan, MD, Assistant Professor of Pediatrics, HMS

2:15–4:30 Stroke – ClassificationFerdinand Buonanno, MD, Assistant Professor of Neurology, HMSEric Grabowski, MD, Associate Professor of Pediatrics, HMS

ImagingPaul Caruso, MD, Instructor in Radiology, HMS

Workshop in Stroke ManagementFerdinand Buonanno, MD, Assistant Professor of Neurology, HMSEric Grabowski, MD, Associate Professor of Pediatrics, HMS

4:30 Closing Remarks: AdjournKatherine Sims, MD, Professor of Neurology, HMS Florian Eichler, MD, Assistant Professor in Neurology, HMS

Program changes/substitutions may be made without notice.