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CHILD & ADOLESCENT PSYCHOPHARMACOLOGY

COURSE DIRECTORS:

FRIDAY-SUNDAY, MARCH 4-6, 2016

Chief, Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHDDirector, Bressler Program for Autism Spectrum DisordersMassachusetts General HospitalProfessor of PsychiatryHarvard Medical School

Associate Chief of Psychiatry, Clinical and Research Program in Pediatric Psychopharmacology and Adult ADHDMassachusetts General HospitalAssociate Professor of PsychiatryHarvard Medical School

Chief, Division of Child and Adolescent PsychiatryDirector, Center for Addiction MedicineMassachusetts General HospitalAssociate Professor of PsychiatryHarvard Medical School

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Welcome to the Massachusetts General Hospital Psychiatry Academy’s Child and Adolescent Psychopharmacology course.

The target audience for this event is psychiatrists, primary care physicians and family physicians, pediatricians, psychologists, nursing professionals, social workers, residents and other mental health and primary care and pediatric clinicians.

Complimentary breakfast and coffee breaks will be available to course participants. Please note that lunch and dinner will be on your own.

Every participant needs to complete the activity evaluation online to claim CME/CEU credits for this course. Please refer to the Evaluation and CME Information document in this syllabus for more information. We strongly encourage you to complete the

claim credit is as follows:

Opportunity for questions will be provided at the end of each module during the panel discussion. Please write your questions on the index cards provided. Cards will be collected during the last 15 minutes of the lecture prior to the start of the panel discussion. Experience has shown that this method is preferable to that of spontaneous questions.

The course materials and PowerPoint presentations are copyright protected by Massachusetts General Hospital, Department of Psychiatry, Division of Postgraduate Education, the faculty members and the appropriate authors. Videotaping and audiotaping are not allowed. Thank you for your cooperation.

During the lectures, we ask that you turn your cell phones and pagers to vibrate or off. We also ask that you do not talk on your cell phones inside the meeting room. Thank you for your cooperation.

For questions or comments, please contact MGH Psychiatry Academy member services at 866-644-7792 or mghcme@mgh.harvard.edu.

CHILD & ADOLESCENT PSYCHOPHARMACOLOGYFRIDAY SUNDAY MARCH 4-6, 2016

ESTIN COPLEY PLACE 10 HUNTINGTON A E , OSTON, MA

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At the end of this educational activity, participants should be able to:

childhood and adolescence. Identify the presentation, diagnosis, and current treatment options available for behavioral problems and pervasive developmental disorders. Discuss the presentation, diagnosis, and current treatment options available for depression, psychosis, manic depression, and anxiety. Compare and contrast basic neuropharmacology, neuropsychologic testing data, psychopharmacologic properties of compounds, and the implications of psychiatric genetics for guiding day-to-day pediatric psychopharmacology treatment. Recognize the risk management issues associated with adolescent substance abuse and smoking, ethical and safe use of psychotropics, suicide risk and prevention, cardiovascular side effects and medical liability of stimulants, and liability prevention in psychopharmacology.

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of McLean Hospital and Massachusetts General Hospital. McLean Hospital is accredited by the ACCME to provide continuing medical education for physicians.

McLean Hospital designates this live activity for a maximum of 25.25 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

The Massachusetts General Hospital Department of Psychiatry is approved by the American Psychological Association to sponsor continuing education (CE) for psychologists. The Massachusetts General Hospital Department of Psychiatry maintains responsibility for this program and its content. This offering meets the criteria for Continuing Education (CE) credits for psychologists.

This program meets the requirements of the Massachusetts Board of Registration in Nursing (244 CMR 5.00) for contact hours of nursing continuing education credit. Advance practice nurses, please note: Educational activities which meet the requirements of the ACCME (such as this activity) count towards 50% of the nursing requirement for ANCC accreditation.

This program has been approved for 25.00 Social Work Continuing Education hours for relicensure, in accordance with 258 CMR. Collaborative of NASW and the Boston College and Simmons Schools of Social Work Authorization Number D 71362.

Physicians: 5 credits meet the criteria of the Massachusetts Board of Registration in Medicine for risk management study.

The American Board of Psychiatry and Neurology has reviewed Child & Adolescent Psychopharmacology 2016 and has approved this program as part of a comprehensive program, which is mandated by the ABMS as a necessary component of

AMA PRA Category 1 Credits™ associated with the activity. Providers should check with their regulatory agencies to determine ways in which AMA PRA Category 1 Credits™copies of brochures, agenda, and other supporting documents.

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7:00AM - 7:45AM

7:45AM - 8:00AM Joseph Biederman, MD; Thomas J. Spencer, MD; Timothy E. Wilens, MD

8:00AM - 8:45AM Joseph Biederman, MD

8:45AM - 9:30AM Pradeep G. Bhide, PhD

9:30AM - 9:45AM

9:45AM - 10:30AM Roy H. Perlis, MD, MSc

10:30AM - 11:15AM Joseph Biederman, MD Pradeep G. Bhide, PhD, Roy H. Perlis, MD, MSc

11:15AM - 12:00PM Joseph Biederman, MD

12:00PM - 1:15PM

1:15PM - 2:00PM Thomas J. Spencer, MD

2:00PM - 2:45PM Timothy E. Wilens, MD

2:45PM - 3:30PM Joseph Biederman, MD Thomas J. Spencer, MD, Timothy E. Wilens, MD

3:30PM - 3:45PM

3:45PM - 4:30PM**

Timothy E. Wilens, MD

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4:30PM - 5:30PM**

Joseph Biederman, MD Thomas J. Spencer, MD; Timothy E. Wilens, MD; Janet Wozniak, MD

5:30PM - 6:30PM

6:30PM - 7:30PM Participants may choose only one seminar presentation to attend.

America Ballroom, 4th Floor

Craig B. Surman, MD Adams/Parliament, 7th Floor

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7:30AM - 8:00AM

8:00AM - 8:45AM Karen D. Wagner, MD, PhD

8:45AM - 9:30AM Janet Wozniak, MD

9:30AM - 9:45AM

9:45AM - 10:30AM Mai Uchida, MD

10:30AM - 11:15AM Janet Wozniak, MD Mai Uchida, MD, Karen D. Wagner, MD, PhD

11:15AM - 12:00PM Abigail Donovan, MD

12:00PM - 1:00PM

1:00PM - 1:45PM Barbara J. Coffey, MD, MS

1:45PM - 2:30PM Joseph Biederman, MD

2:30PM - 3:15PM Joseph Biederman, MD Abigail Donovan, MD, Barbara J. Coffey, MD, MS

3:15PM - 3:30PM

3:30PM - 4:15PM Aude Henin, PhD

4:15PM - 5:00PM Ronna Fried, EdD

5:00PM - 5:30PM Thomas J. Spencer, MD Aude Henin, PhD, Ronna Fried, EdD

5:30PM - 6:30PM

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6:30PM - 7:30PM

Participants may choose only one seminar presentation to attend. Ronna Fried, EdD Adams/Parliament, 7th Floor Andrea E. Spencer, MD America Ballroom, 4th Floor

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7:00AM - 8:00AM

8:00AM - 8:45AM John Gabrieli, PhD

8:45AM - 9:30AM Daniel A. Geller, MD

9:30AM - 10:15AM Kyle A. Williams, MD, PhD

10:15AM - 11:00AM Kamryn T. Eddy, PhD

11:00AM - 11:15AM

11:15AM - 12:00PM** Paula K. Rauch, MD

12:00PM - 12:45PM Daniel A. Geller, MD John Gabrieli, PhD, Kamryn T. Eddy, PhD, Kyle A. Williams, MD, PhD,

Paula K. Rauch, MD

12:45PM - 1:45PM

1:45PM - 2:30PM** Jefferson B. Prince, MD

2:30PM - 3:15PM** Ronald Schouten, MD, JD

3:15PM - 4:00PM Annah N. Abrams, MD

4:00PM - 4:45PM Jefferson B. Prince, MD Ronald Schouten, MD, JD, Annah N. Abrams, MD

4:45PM

**Session eligible for Risk Management Credit

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Annah N. Abrams, MDChief, Division of Pediatric Psycho-Oncology, Pediatric Hematology Oncology Unit, Attending, Child Psychiatry Consultation Liaison Service, Massachusetts General Hospital, Assistant Professor of Psychiatry, Harvard Medical School

Pradeep G. Bhide, PhDProfessor, Jim and Betty Ann Rodgers Eminent Scholar Chair of Developmental Neuroscience, Director, Center for Brain Repair, Department of Biomedical Sciences, Florida State University College of Medicine

Barbara J. Coffey, MD, MSProfessor, Department of Psychiatry, Chief, Tics and Tourette’s Clinical and Research Program, Tourette Association of America Center of Excellence, Director of Education in Child and Adolescent Psychiatry, Icahn School of Medicine at Mount Sinai, Research Psychiatrist, Nathan Kline Institute for Psychiatric Research

Abigail Donovan, MDDirector, First Episode and Early Psychosis Program, Associate Director, Acute Psychiatry Service, Massachusetts General Hospital, Assistant Professor of Psychiatry, Harvard Medical School

Kamryn T. Eddy, PhDCo-Director, Eating Disorders Clinical and Research Program, Staff Psychologist, Marjorie E. Korff, PACT (Parenting At a Challenging Time) Program, Massachusetts General Hospital, Associate Professor of Psychology (Psychiatry), Harvard Medical School

Ronna Fried, EdDCo-Director of Neuropsychology, Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Assistant Professor of Psychology, Harvard Medical School

John Gabrieli, PhDDirector, Martinos Imaging Center, Grover Hermann Professor in Health Sciences and Technology & Cognitive Neuroscience, Massachusetts Institute of Technology

Daniel A. Geller, MDDirector, Pediatric OCD and Tic Disorder Program, Massachusetts General Hospital, Associate Professor of Psychiatry, Harvard Medical School

Aude Henin, PhDCo-Director, Child Cognitive-Behavioral Therapy Program, Director, Cognitive Behavior Therapy Program, Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital

Roy H. Perlis, MD, MScMedical Director, Bipolar Clinic and Research Program Principal Investigator, Center for Human Genetic Research, Massachusetts General Hospital, Associate Professor of Psychiatry, Harvard Medical School

Jefferson B. Prince, MDDirector of Child Psychiatry, North Shore Medical Center, Staff, Child Psychiatry and Pediatric Psychopharmacology Clinics, Massachusetts General Hospital

Paula K. Rauch, MDTimothy Christopher Davidson Chair of Psychiatry, Program Director, Family Support and Outreach, Red Sox Foundation & MGH Home Base Program, Director, Marjorie E. Korff PACT Program (Parenting At a Challenging Time), Massachusetts General Hospital

Ronald Schouten, MD, JDDirector, Law & Psychiatry Service, Massachusetts General Hospital, Associate Professor of Psychiatry, Harvard Medical School

Joseph Biederman, MDDirector, Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Professor of Psychiatry, Harvard Medical School

Thomas J. Spencer, MDAssociate Chief, Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, Associate Professor of Psychiatry,Harvard Medical School

Timothy E. Wilens, MDDirector, Substance Abuse Services in Pediatric Psychopharmacology, Director, Center for Addiction Medicine, Massachusetts General Hospital, Associate Professor of Psychiatry, Harvard Medical School

Course Directors:

Faculty:

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Craig B. Surman, MD

Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Assistant Professor of Psychiatry, Harvard Medical School

Mai Uchida, MDStaff Physician, Clinical and Research Programs in Pediatric Psychopharmacology, Massachusetts General Hospital, Assistant Professor of Psychiatry, Harvard Medical School

Karen D. Wagner, MD, PhDMarie B. Gale Centennial Professor & Vice Chair, Department of Psychiatry & Behavioral Sciences, Director, Division of Child & Adolescent Psychiatry, University of Texas Medical Branch at Galveston

Kyle A. Williams, MD, PhDDirector, Pediatric Neuropsychiatry and Immunology Program, Massachusetts General Hospital, Instructor, Department of Psychiatry, Harvard Medical School

Janet Wozniak, MDDirector, Child and Adolescent Outpatient Department, Director, Pediatric Bipolar Disorder Clinical and Research Program, Massachusetts General Hospital, Associate Professor of Psychiatry, Harvard Medical School

Assistant in Psychiatry, Massachusetts General Hospital, Instructor in Psychiatry, Harvard Medical School

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In accord with the disclosure policy of McLean Hospital as well as guidelines set forth by the Accreditation Council on Continuing Medical Education, speakers have been asked to disclose any relationship they have to companies producing pharmaceuticals, medical equipment, devices, etc. that might be germane to the content of their lectures. Such disclosure is not intended to suggest or condone bias in any presentation, but is elicited to provide participants with information that might be of potential importance to their evaluation of a given talk. In addition, faculty have been asked to describe any “off label” uses of pharmaceutical products and devices.

Jane Pimental, MPH David H. Rubin, MD (Reviewer)

Annah N. Abrams, MDAbigail Donovan, MDKamryn T. Eddy, PhDJohn Gabrieli, PhDDaniel A. Geller, MDRonald Schouten, MD, JDMai Uchida, MD

Pradeep G. Bhide, PhD Avekshan, LLC.

Joseph Biederman, MD The Department of Defense, Food Drug Administration, Ironshore, Lundbeck, Magceutics

Barbara J. Coffey, MD, MS American Academy of Child and Adolescent Psychiatry

Astra Zeneca, Auspex/Teva, Catalyst, NIMH, Shire, Tourette Association of America, Neurocrine

Genco Sciences, Auspex/Teva Tourette Association of America

Ronna Fried, EdD Lundbeck

Aude Henin, PhD Clintara, Alkermes

Oxford University Press

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Roy H. Perlis, MD, MSc

Biomedical, and RID Ventures Concordant Rater Systems (now Bracket, a Medco subsidiary)

Jefferson B. Prince, MD Harvard Health Publications almost Depressed Book

Paula K. Rauch, MD McGraw Hill Publishing Company

Andrea E. Spencer, MD Sunovion

Thomas J. Spencer, MD Alcobra, Lundbeck, Sunovion, FDA, Department of Defense

Alcobra, Lundbeck, Inc., Shire Laboratories, Inc., Sunovion

Alcobra Dr. Spencer receives research support from Royalties and Licensing Fees on

copyrighted ADHD scales through MGH Corporate Sponsored Research and Licensing.

Craig B. Surman, MD Rhodes Pharmaceuticals, Ironshore, Shire Pharmaceuticals

Magceutics, Pamlab

Karen D. Wagner, MD, PhD UBM Medica, Nevada Psychiatric Association, American Society of Clinical Psychopharmacology

Timothy E. Wilens, MD NIH, NIDA

Euthymics/Neurovance, Ironshore, Sunovion, TRIS, US National Football League ERM Associates, U.S. Minor/Major League Baseball, Bay Cove Human Services Clinical Services and Phoenix House

Guilford Press, Cambridge Press, Elsevier: Straight Talk About Psychiatric Medications for Kids (Guilford Press), ADHD in Children and Adults (Cambridge Press), and Massachusetts General Hospital Comprehensive Clinical Psychiatry (Elsevier)/ Psychopharmacology & Neurotherapeutics (Elsevier) .

Dr. Wilens is co/owner of a copyrighted diagnostic questionnaire Before School Functioning Questionnaire (BFSQ). Dr. Wilens has a licensing agreement with Ironshore BSFQ Questionnaire.

Kyle A. Williams, MD, PhD Grifols Therapeutics, Inc.

Janet Wozniak, MD Bantam Books Cambridge University Press and UptoDate

Cantor Colburn, Merck, UCB, and Xenoport UCB Pharma, Purdue, and NeuroMetrix

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McLean Hospital has implemented a process to resolve COI for each CME activity. In order to help ensure content objectivity, independence, fair balance and ensure that the content is aligned with the interest of the public, McLean

* “Something of value” refers to an equity position, receipt of royalties, consultantship, funding by a research grant, receiving honoraria for educational services elsewhere, or to any other relationship to a company that

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Suzanne Bender, MD Gastrointestinal Pediatric

PsychiatryFriday, March 4, 10:30M - 11:30AM

Substance Abuse Friday, March 4, 4:30PM - 5:30PM

Craig B. Surman, MD Friday, March 4, 4:30PM - 5:30PM

Mai Uchida, MD Mood Disorders Saturday, March 5, 11:00AM 12:00PM

Tolga Atilla Ceranoglu, MD Psychopharmacology of Autism Spectrum Disorder

Saturday, March 5, 3:00PM - 4:00PM

Ronna Fried, EdD Neuropsychological Testing and Educational Planning

Saturday, March 5, 3:15PM - 4:15PM

Andrea E. Spencer, MD ADHD and PTSD Saturday, March 5, 4:30PM - 5:30PM

Kamryn T. Eddy, PhD Eating Disorders Sunday, March 6, 11:00AM - 12:00PM

Annah N. Abrams, MD Consult Liaison Issues Sunday, March 6, 2:15PM - 3:15PM

Jefferson B. Prince, MD Mindfulness in Pediatric Psychopharmacology

Sunday, March 6, 2:30PM - 3:30PM

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