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Chemistry Beyond the Ordinary • Custom Synthesis • cGMP Manufacturing • Monomers & Polymers • Microspheres & Particles • Histology & Laboratory Reagents • High Performance Electronic Materials • Polymers for Biomedical Applications • Contract Manufacturing polysciences.com “Your Partner for Collaborative Innovation”

Chemistry Beyond the Ordinary - Home | Polysciences Beyond the Ordinary • Custom Synthesis • cGMP Manufacturing • Monomers & Polymers • Microspheres & Particles • Histology

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Page 1: Chemistry Beyond the Ordinary - Home | Polysciences Beyond the Ordinary • Custom Synthesis • cGMP Manufacturing • Monomers & Polymers • Microspheres & Particles • Histology

Chemistry Beyond the Ordinary• Custom Synthesis

• cGMP Manufacturing

• Monomers & Polymers

• Microspheres & Particles

• Histology & Laboratory Reagents

• High Performance Electronic Materials

• Polymers for Biomedical Applications

• Contract Manufacturing

polysciences.com

“Your Partner for Collaborative Innovation”

Page 2: Chemistry Beyond the Ordinary - Home | Polysciences Beyond the Ordinary • Custom Synthesis • cGMP Manufacturing • Monomers & Polymers • Microspheres & Particles • Histology

Polysciences, Inc. provides custom manufacturing and development of fine chemicals and intermediates for drug discovery, biotechnology, medical devices, cosmetics, electronics and analytical chemistry industries in large scale. Our manufacturing plant in Warrington, PA consists of four buildings totaling over 200,000 square feet containing modern reactors, purification equipment and quality control departments.

We work with you to take your project from concept through laboratory scale synthesis and see it through to commercial manufacturing. Whether it is a start-up product, pilot plant scale-up or full scale production, we can be an important link between your creative idea and commercialization of your product. Our expertise, custom manufacturing capabilities and rigorous quality standards allow us to provide you with the exact composition, properties and purity you need.

Production FacilitiesOur Corporate Headquarters and primary manufacturing facilities are located in Warrington Pennsylvania, approximately 20 miles north of Philadelphia. Situated on more than 7 acres, our 135,000 square feet of space are allocated to manufacturing and warehousing as well as finance, human resources, purchasing, marketing, and customer service. Less than a mile from headquarters, we have an additional 70,000 square feet of manufacturing, laboratory, and office space particularly serving our electronics chemicals business segment and explosion proof manufacturing suites.

Features at our Pennsylvania Facilities Include:

• ISO 13485:2003 & ISO 9001:2008 Certified

• Class 8 cleanrooms

• Laboratory production facilities and pilot plant built and operated as per cGMP

• Registered FDA establishment #2518071

• Complete range of equipment to provide flexibility in the scale of operations

• Fully equipped synthesis laboratories with over 30 hoods

• Manufacturing facilities with stainless steel and glass-lined reactors

In addition to our Pennsylvania operations, we operate and maintain facilities in Germany and Indiana.

cGMP Manufacturing Facility & Services

Why Partner with Polysciences?• Over 50 years experience in custom synthesized polymers

tailored to your needs. In addition to homopolymers, our products include monomers, polymers and co-polymers with enhanced chain end-groups

• An experienced team of research scientists, engineers and business development staff dedicated to provide customized solutions

• Resources available to provide the flexibility to produce quantities with scales ranging from milligrams to thousands of kilograms

• Commitment to quality that gives our customers confidence in our products and manufacturing capabilities

• Distribution anywhere in the world

• Our team of Ph.D. monomer/polymer chemists and researchers can create new possibilities for your research

• Chemistry support services for the synthesis of targeted compounds, sourcing of starting materials and step-wise product improvement

• Technical support that exceeds your needs

• All requests for services and products are considered confidential

U.S. & Canada: (800) 523-2575 or (215) 343-6484, [email protected] Europe: +(49) 6201 845 20 0, [email protected] | Asia: (886) 2 8712 0600, [email protected]

Page 3: Chemistry Beyond the Ordinary - Home | Polysciences Beyond the Ordinary • Custom Synthesis • cGMP Manufacturing • Monomers & Polymers • Microspheres & Particles • Histology

Microspheres and ParticlesCustom & Bulk ManufacturingOur Microspheres and Particles division offers a wide range of products and services for custom and bulk manufacturing. Product areas include; Polymer Microspheres, Dyed Microspheres, Fluorescent Microspheres, Protein Coated, Uniform Silica, Magnetic Microspheres and Flow Cytometry products.

Specialty & Bulk ManufacturingOur Specialty & Bulk Chemicals Group offers extensive expertise in producing and sourcing a vast range of products for your production and research applications. Bulk chemicals include reagents, microspheres and intermediates available in multi-kilogram quantities.

Custom Synthesis OverviewThe core service offered by Polysciences, Inc. is custom synthesis of milligram to multi-kilogram quantities of compounds for use in research and development.

Our objective is to become a partner with innovative companies, providing a complete range of custom synthesis and cGMP contract manufacturing services.

• Monomer synthesis• Polymer synthesis• Homopolymers and co-polymers• Unique and ultra-pure specialty chemicals• Different end group chemistries• Scale from milligrams to thousands of kilograms• Molecular weights ranging from a few thousand to several million

Europe: +(49) 6201 845 20 0, [email protected] | Asia: (886) 2 8712 0600, [email protected]

Coating & Surface Modification• Proteins• Spacers / Linkers• Other molecules

Dyeing & Loading• Surface-immobilized or internal fluorophores• Visible colors• Other hydrophobic compounds• Targeted or multiple intensities

Synthesis• Magnetic Beads• Polystyrene and methacrylate polymers• Functionalized and crosslinked polymers• Silica

Services• Dilution• Drying

Applications• Cell separation• Magnetic particle assay development• Agglutination tests / assays• Flow cytometry• Fluorescence microscopy• Molecular diagnostics

Product Areas Include

• Polymers for biomedical applications• Poly Ethylene Vinyl Acetate (PEVA)• Methacrylates• Organic intermediates• Electronic materials• Raw materials for personal care products• Specialty monomer and polymer synthesis• Polylactides and other biodegradable polymers• Silicones, adhesives and copolymers• Epoxides / Anhydrides / Imides• Fluorescent acrylic monomers• Reactive polymers• Water soluble polymers• Numerous synthetic and purification methods

Page 4: Chemistry Beyond the Ordinary - Home | Polysciences Beyond the Ordinary • Custom Synthesis • cGMP Manufacturing • Monomers & Polymers • Microspheres & Particles • Histology

U.S. Corporate Headquarters 400 Valley Road, Warrington, PA

424 Valley Rd. Facility, Warrington, PA 1993 County Line Rd. Facility, Warrington, PA 1981 County Line Rd. Facility, Warrington, PA

Polysciences GmbH, Hirschberg, GermanyBangs Laboratories, Inc. Fishers, Indiana Polysciences Asia Pacific, Inc., Taipei, Taiwan

High Performance Electronic MaterialsPolysciences, Inc. has been serving the global scientific community for over 50 years. We provide unique organic materials and a broad product line of electronic adhesives, coatings and encapsulants. Specializing in custom formulations to meet your distinct needs.

With our expertise, we work with you to design and synthesize your unique product...

• New and unique monomers• New particle architectures• Electronic grade organic materials• Photoreactive monomers and polymers

Consider the advantages...

• Responsive, rapid turnaround of your project• Complete confidentiality and protection of your

intellectual property and its value• Economic alternative to in-house activities • EPA registered facility with expertise in handling

sensitive, complex and hazardous materials

Whether you are scaling up your R&D process or creating a new process, we work with you to turn possibilities into opportunities. We can produce your product in a one-off run or manufacture your product on a routine basis. From milligrams to thousands of kilograms per year, you can count on Polysciences to provide you with consistent batch-to-batch quality, on-time delivery and maximum value.

Histology & Laboratory ReagentsPolysciences, Inc. is an established supplier of custom, specialty and fine chemicals for customers in the medical devices, biotechnology and analytical chemistry industries. We have an experienced staff of Ph.D. production and synthesis chemists that can assist you in accomplishing your goals on time and within budget.

Ultrapure Monomers & Organic IntermediatesCustom ultrapure monomers and organic intermediates serve as an essential building block in the production of many medical devices and polymer enhanced drug entities. Custom ultrapure monomers and organic intermediates can be manufactured and tailored to suit your needs in our cGMP compliant laboratories.

• Certified Dyes• Embedding Kits

• Electrophoresis Products• Special & Routine Stains

• Fixatives• Paraffins

• Embedding Molds• Immunohistochemistry Products

U.S. Corporate Headquarters | 400 Valley Rd, Warrington, PA 18976 | 1(800) 523-2575 (215) 343-6484 | Fax 1(800) 343-3291 | [email protected] Europe GmbH | Badener Str. 13, 69493 Hirschberg an der Bergstr., Germany | +(49) 6201 845 20 0 | Fax +(49) 6201 845 20 20 | [email protected] Asia Pacific, Inc. | 2F-1, 207 DunHua N. Rd. Taipei, Taiwan 10595 | (886) 2 8712 0600 | Fax (886) 2 8712 2677 | [email protected]