Chemistry 361Chemistry 361

Truis Smith-PalmerTruis Smith-Palmer

(Trooooos)(Trooooos)

Dr S-PDr S-P

Chem 361 WebsiteChem 361 Website

http://people.stfx.ca/tsmithpa/Chem361//

Themes in 361Themes in 361 SamplingSampling – collecting samples – collecting samples Sample prepSample prep – – examples in lab and examples in lab and

application highlightsapplication highlights InstrumentationInstrumentation

DesignDesign Principle of operationPrinciple of operation Running the instrument (labs)Running the instrument (labs) Interpreting resultsInterpreting results

Quality ControlQuality Control – running standards – running standards StatisticsStatistics – reproducibility, LOD, – reproducibility, LOD,

confidence limitsconfidence limits

““ANALYTICAL CHEMISTRY ANALYTICAL CHEMISTRY IS NOTIS NOT

SPECTROMETERS,SPECTROMETERS,

POLAROGRAPHS,POLAROGRAPHS,

ELECTRON MICROPROBES,ELECTRON MICROPROBES,

ETC.ETC.

IT ISIT IS

EXPERIMENTATION,EXPERIMENTATION,

OBSERVATION,OBSERVATION,

DEVELOPING FACTS,DEVELOPING FACTS,

AND DRAWING CONCLUSIONS.”AND DRAWING CONCLUSIONS.”

West PW West PW

in Analytical Chemistry (46) 1974in Analytical Chemistry (46) 1974

ANALYTICAL METHODOLOGYANALYTICAL METHODOLOGY

IDENTIFICATIONIDENTIFICATION

DETERMINATION or ASSAYDETERMINATION or ASSAY

ANALYSISANALYSIS

QUANTITATIONQUANTITATION

ANALYTEANALYTE

VALIDATIONVALIDATION

METHODS or PROTOCOLSMETHODS or PROTOCOLS

TECHNIQUESTECHNIQUES

SOLVING A PROBLEMSOLVING A PROBLEM

TextText

Harris, 8Harris, 8thth Edition Edition You will receive Power point handouts You will receive Power point handouts They are the They are the basicsbasics of lectures – you of lectures – you

should supplement them with notes.should supplement them with notes. Chapter 0 – very good overviewChapter 0 – very good overview Chapter 1 – Units, concentration Chapter 1 – Units, concentration

calculations and dilutions – should be calculations and dilutions – should be revisionrevision

LabsLabs

Need to write prelabsNeed to write prelabs Need to write web-quizzesNeed to write web-quizzes Need hard covered notebooks, pens Need hard covered notebooks, pens

and markers for glassware – and and markers for glassware – and safety glassessafety glasses

Lab package available including Lab package available including notebooks $35 (includes $10 for notebooks $35 (includes $10 for handouts)handouts)

Buy on Friday after class.Buy on Friday after class.

First LabFirst Lab 1010thth, 11, 11thth September September Meet in lab 3037 at 2.15 pm for safety talk Meet in lab 3037 at 2.15 pm for safety talk

and introduction to the first wet lab.and introduction to the first wet lab. Bring lab manual.Bring lab manual. We will then go to the computer labWe will then go to the computer lab Bring calculator able to do statistic calcsBring calculator able to do statistic calcs We can help if you have lost instructionsWe can help if you have lost instructions Dry lab – will do sample calcs and Dry lab – will do sample calcs and

graphing. graphing. There is a There is a practice example and answers practice example and answers

on the web page at BOTTOM of list of labson the web page at BOTTOM of list of labsExcel – pp 43-47 of Harris and in Lab ManualExcel – pp 43-47 of Harris and in Lab Manual

Second labSecond lab

In the 361 labIn the 361 lab PartnersPartners You are expected to thinkYou are expected to think

Tutorial?Tutorial?

Mostly to help write up labsMostly to help write up labs Come see me individually – or Come see me individually – or

suggest a tutorial time.suggest a tutorial time.

Class ombudsman?Class ombudsman?

AssignmentsAssignments Library assignment Library assignment With labs: Simplex, IR, With labs: Simplex, IR,

Fluorescence,RadiochemistryFluorescence,Radiochemistry Some problems from textbooksSome problems from textbooks Second assignment on FluorescenceSecond assignment on Fluorescence Please bring calculator to class Please bring calculator to class

because every now and then I because every now and then I will ask you to do calculations in will ask you to do calculations in classclass

First AssignmentFirst Assignment

Finding AOAC methodsFinding AOAC methods Come see me if necessary and I will Come see me if necessary and I will

help you interpret it and go over help you interpret it and go over what are the important partswhat are the important parts

Due Friday 21Due Friday 21stst September. 4.30 pm. September. 4.30 pm. Sign –up sheet for your chosen topic Sign –up sheet for your chosen topic

outside my officeoutside my office

QuizzesQuizzes

October Quiz Thursday 11 OctoberOctober Quiz Thursday 11 October

November Quiz: Thursday 22 November Quiz: Thursday 22 NovemberNovember

Lab Quiz: TBA Lab Quiz: TBA