2000 multi-membered N-heterocycles

multi-membered N-heterocyclesR 0690

16 - 155Synthesis of the 4-Arylindole Portion of the Antitumor Agent Di-azonamide and Related Studies. — Starting from the commerciallyavailable bromoarene (I), a high yielding synthesis of the CDG ring (VIII) ofdiazonamide is described. Furthermore, introduction of the 2-chlorosubstituent[cf. (XI) and (XIII)] is achieved, which may allow useful transformation of theskeleton. — (CHAN, FIONA; MAGNUS, PHILIP; MCIVER, EDWARD G.;Tetrahedron Lett. 41 (2000) 6, 835-838; Dep. Chem. Biochem., Univ. Tex.,Austin, TX 78712, USA; EN)

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