Furan derivativesR 0060 DOI: 10.1002/chin.201135106

Highly Regioselective Synthesis of 2,3,5-Trisubstituted Furans via Phosphine-Cat-alyzed Ring-Opening Cycloisomerization Reactions of Cyclopropenyl Dicarbox-ylates. — The regioselective synthesis of trisubstituted furans (II) is achieved via phos-phine-catalyzed ring-opening cycloisomerization reactions of the functionalized cyclo-propenyl carboxylates (I) with moderate to very good yields. With alkyl groups as sub-stituents, the reactions proceed smoothly. However, substituents bearing an unprotected hydroxyl group or differently substituted aryl groups influence the reaction course essentially. — (CHEN, J.; NI, S.; MA*, S.; Synlett 2011, 7, 931-934, http://dx.doi.org/10.1055/s-0030-1259904 ; State Key Lab. Organomet. Chem., Shanghai Inst. Org. Chem., Chin. Acad. Sci., Shanghai 200032, Peop. Rep. China; Eng.) — H. Hoennerscheid

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