1999 halogen compounds

halogen compounds (benzene compounds)Q 0090

38 - 095Coupling of 2-Substituted 1-Fluorovinylstannanes with OrganicHalides Catalyzed by Palladium(0)/Copper(I) Iodide. A Mild andStereospecific Method to Monofluoroolefins. — (E)- and (Z)-vinylstannanes give, with a variety of aryl and vinyl iodides, under palladiumcatalysis and CuI as cocatalyst, monofluoroolefins with the same double bondgeometry present in the coupling partner. Many functional groups are toleratedon the substrates. Monofluorovinyl ketones are also obtained under mildconditions by coupling with acid chlorides. — (CHEN, CHEN; WILCOXEN,KEITH; ZHU, YUN-FEI; KIM, KYUNG-IL; MCCARTHY, JAMES R.; J. Org.Chem. 64 (1999) 10, 3476-3482; Dep. Med. Chem., Neurocrine Biosci., Inc.,San Diego, CA 92121, USA; EN)

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